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Gene Dmel\Tudor-SN

General Information
Symbol	Dmel\Tudor-SN	Species	D. melanogaster
Name	Tudor-SN	Annotation symbol	CG7008
Feature type	protein_coding_gene	FlyBase ID	FBgn0035121
Gene Model Status	Current	Stock availability	6 publicly available
Also Known As	TSN
Genomic Location
Chromosome (arm)	3L	Recombination map
Cytogenetic map	61B3-61B3	Sequence location	3L:259,043..264,380 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene Tudor-SN is referred to in FlyBase by the symbol Dmel\Tudor-SN (CG7008, FBgn0035121). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: transcription coactivator activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: gene silencing by RNA. 18 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: RNA-induced silencing complex, nuclease component Tudor-SN; Staphylococcal nuclease (SNase-like); Staphylococcal nuclease (SNase-like), OB-fold; Tudor domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression. Peak expression observed within 00-18 hour embryonic stages, during early larval stages, during early pupal stages, in adult female stages. Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: larval central nervous system, larval/adult midgut, larval hindgut, larval/adult Malpighian tubules, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male accessory gland, larval carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, adult central nervous system, adult crop, adult hindgut, adult heart, virgin spermatheca, adult testis, adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1640241_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of Tudor-SN. Gene sequence location is 3L:259043..264380.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 61B3-61B3   Limits computationally determined from genome sequence between P{PZ}trh10512 and P{EP}EP3104EP3104
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\Tudor-SN for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.45 Low-frequency RNA-seq exon junction(s) not annotated. DGC clone LD06532 appears problematic: incomplete CDS
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) Tudor-SN-RA FBtr0072519  NM_138177   3159   926 Tudor-SN-RB FBtr0332107  NM_001274266   3411   926
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein Tudor-SN-PA   FBpp0072419   103.1   926   8.22     NP_612021   AAF47366 Tudor-SN-PB   FBpp0304417   103.1   926   8.22     NP_001261195   AGB93890
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Tudor domain (IPR002999) Staphylococcal nuclease (SNase-like) (IPR006021) Staphylococcal nuclease (SNase-like), OB-fold (IPR016071) RNA-induced silencing complex, nuclease component Tudor-SN (IPR016685)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA201864   AA202451   AA246394   AA263398   AA263679   AA264661   AA391383   AA391501   AA392769   AA439312   AA536489   AA540071   AA540214   AA540337   AA540339   AA540503   AA695478   AA698834   AA950063   AA979676   AE014296 AAF47366   AE014296 AGB93890   AI061789   AI518608   AI534116   AQ025060   AQ254665   AQ254725   AW941619   AY069361 AAL39506   BF489063   BG636412   BH634797   BH759351   BI171997   BI228311   BI229972   BI232471   BI234847   BI235504   BI239463   BI239682   BI240272   BI240457   BI240543   BI240641   BI241184   BI241971   BI243265   BI243564   BI362334   BI362417   BI363258   BI363531   BI364370   BI365956   BI367097   BI374477   BI484033   BI484058   BI485409   BI487154   BI577294   BI580374   BI580567   BI640705   BP552187   BP560381   BQ103429   BT003270 AAO25027   CK661706   CL525966   CO178003   CO183981   CO184864   CO185612   CO196656   CO264853   CO272236   CO273146   CO273572   CO279565   CO282143   CO298725   CO300776   CO303307   CO306709   CO311044   CO311120   CO313103   CO315952   CO317380   CO318281   CO332117   CO332987   EC051262   EC058281   EC060246   EC065157   EC066438   EC066457   EC068389   EC077579   EC199559   EC200140   EC213515   EC214664   EC215459   EC215605   EC216583   EC220866   EC226031   EC228257   EC234409   EC236927   EC239453   EC243716   EC243804   EC248076   EV576098   EV589949   EV591562
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9W0S7 Q8T0F1
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
in situ Stage Tissue/Position (including subcellular localization) Reference embryonic stage 1 -- 3   organism   (Fisher et al., 2012) Comment:maternally deposited embryonic stage 4 -- 6   organism   (Fisher et al., 2012) embryonic stage 7 -- 8   organism | ubiquitous   (Fisher et al., 2012) embryonic stage 9 -- 10   organism | ubiquitous   (Fisher et al., 2012) embryonic stage 11 -- 12   organism | ubiquitous   (Fisher et al., 2012) embryonic stage 13 -- 16   organism | ubiquitous   (Fisher et al., 2012)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
mass spectroscopy Stage Tissue/Position (including subcellular localization) Reference day 7 of adulthood -- day 49 of adulthood   adult heart   (Cammarato et al., 2011)
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
lipid particle inferred from direct assay (Beller et al., 2006) microtubule associated complex inferred from direct assay (Hughes et al., 2008)
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: larval central nervous system, larval/adult midgut, larval hindgut, larval/adult Malpighian tubules, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male accessory gland, larval carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, adult central nervous system, adult crop, adult hindgut, adult heart, virgin spermatheca, adult testis, adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    834.825 Larval Midgut    710 Larval Hindgut    929 Larval Malpighian Tubules    818.5 Larval Fat Body    1061.2 Larval Salivary Gland    3011.3 Larval Trachea    1258.125 Larval Carcass    1355.3 Adult Head    311.7 Adult Eye    201.65 Adult Brain    238.4 Adult Thoracic-Abdominal Ganglion    206.4 Adult Crop    459.7 Adult Midgut    753.5 Adult Hindgut    365.9 Adult Malpighian Tubules    532.3 Adult Fat Body    747.7 Adult Salivary Gland    1610.7 Adult Heart    405.3 Adult VirginFemale Spermatheca    452.8 Adult InseminatedFemale Spermatheca    689.5 Adult Ovary    1305.7 Adult Testis    272 Adult Male Accessory Gland    1739.2 Adult Carcass    389.2 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System  (834.825) Larval Midgut  (710) Larval Hindgut  (929) Larval Malpighian Tubules  (818.5) Larval Fat Body  (1061.2) Larval Salivary Gland  (3011.3) Larval Trachea  (1258.125) Larval Carcass  (1355.3) Adult Head    311.7 Adult Eye    201.65 Adult Brain    238.4 Adult Thoracic-Abdominal Ganglion    206.4 Adult Crop    459.7 Adult Midgut  (753.5) Adult Hindgut    365.9 Adult Malpighian Tubules  532.3 Adult Fat Body  (747.7) Adult Salivary Gland  (1610.7) Adult Heart    405.3 Adult VirginFemale Spermatheca    452.8 Adult InseminatedFemale Spermatheca  (689.5) Adult Ovary  (1305.7) Adult Testis    272 Adult Male Accessory Gland  (1739.2) Adult Carcass    389.2 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    834.825 Larval Midgut    710 Larval Hindgut    929 Larval Malpighian Tubules    818.5 Larval Fat Body  1061.2 Larval Salivary Gland  (3011.3) Larval Trachea  (1258.125) Larval Carcass  (1355.3) Adult Head    311.7 Adult Eye    201.65 Adult Brain    238.4 Adult Thoracic-Abdominal Ganglion    206.4 Adult Crop    459.7 Adult Midgut    753.5 Adult Hindgut    365.9 Adult Malpighian Tubules    532.3 Adult Fat Body    747.7 Adult Salivary Gland  (1610.7) Adult Heart    405.3 Adult VirginFemale Spermatheca    452.8 Adult InseminatedFemale Spermatheca    689.5 Adult Ovary  (1305.7) Adult Testis    272 Adult Male Accessory Gland  (1739.2) Adult Carcass    389.2 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    834.825 Larval Midgut    710 Larval Hindgut    929 Larval Malpighian Tubules    818.5 Larval Fat Body    1061.2 Larval Salivary Gland    3011.3 Larval Trachea    1258.125 Larval Carcass    1355.3 Adult Head    311.7 Adult Eye    201.65 Adult Brain    238.4 Adult Thoracic-Abdominal Ganglion    206.4 Adult Crop    459.7 Adult Midgut    753.5 Adult Hindgut    365.9 Adult Malpighian Tubules    532.3 Adult Fat Body    747.7 Adult Salivary Gland    1610.7 Adult Heart    405.3 Adult VirginFemale Spermatheca    452.8 Adult InseminatedFemale Spermatheca    689.5 Adult Ovary    1305.7 Adult Testis    272 Adult Male Accessory Gland    1739.2 Adult Carcass    389.2 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    834.825 Larval Midgut    710 Larval Hindgut    929 Larval Malpighian Tubules    818.5 Larval Fat Body    1061.2 Larval Salivary Gland    3011.3 Larval Trachea    1258.125 Larval Carcass    1355.3 Adult Head    311.7 Adult Eye    201.65 Adult Brain    238.4 Adult Thoracic-Abdominal Ganglion    206.4 Adult Crop    459.7 Adult Midgut    753.5 Adult Hindgut    365.9 Adult Malpighian Tubules    532.3 Adult Fat Body    747.7 Adult Salivary Gland    1610.7 Adult Heart    405.3 Adult VirginFemale Spermatheca    452.8 Adult InseminatedFemale Spermatheca    689.5 Adult Ovary    1305.7 Adult Testis    272 Adult Male Accessory Gland    1739.2 Adult Carcass    389.2 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System  (834.825) Larval Midgut  710 Larval Hindgut  (929) Larval Malpighian Tubules  (818.5) Larval Fat Body  (1061.2) Larval Salivary Gland  (3011.3) Larval Trachea  (1258.125) Larval Carcass  (1355.3) Adult Head    311.7 Adult Eye    201.65 Adult Brain    238.4 Adult Thoracic-Abdominal Ganglion    206.4 Adult Crop    459.7 Adult Midgut  753.5 Adult Hindgut    365.9 Adult Malpighian Tubules  532.3 Adult Fat Body  747.7 Adult Salivary Gland  (1610.7) Adult Heart    405.3 Adult VirginFemale Spermatheca    452.8 Adult InseminatedFemale Spermatheca  689.5 Adult Ovary  (1305.7) Adult Testis    272 Adult Male Accessory Gland  (1739.2) Adult Carcass    389.2 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    834.825 Larval Midgut    710 Larval Hindgut    929 Larval Malpighian Tubules    818.5 Larval Fat Body  1061.2 Larval Salivary Gland  (3011.3) Larval Trachea  1258.125 Larval Carcass  1355.3 Adult Head    311.7 Adult Eye    201.65 Adult Brain    238.4 Adult Thoracic-Abdominal Ganglion    206.4 Adult Crop    459.7 Adult Midgut    753.5 Adult Hindgut    365.9 Adult Malpighian Tubules    532.3 Adult Fat Body    747.7 Adult Salivary Gland  1610.7 Adult Heart    405.3 Adult VirginFemale Spermatheca    452.8 Adult InseminatedFemale Spermatheca    689.5 Adult Ovary  1305.7 Adult Testis    272 Adult Male Accessory Gland  (1739.2) Adult Carcass    389.2 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    834.825 Larval Midgut    710 Larval Hindgut    929 Larval Malpighian Tubules    818.5 Larval Fat Body    1061.2 Larval Salivary Gland    3011.3 Larval Trachea    1258.125 Larval Carcass    1355.3 Adult Head    311.7 Adult Eye    201.65 Adult Brain    238.4 Adult Thoracic-Abdominal Ganglion    206.4 Adult Crop    459.7 Adult Midgut    753.5 Adult Hindgut    365.9 Adult Malpighian Tubules    532.3 Adult Fat Body    747.7 Adult Salivary Gland    1610.7 Adult Heart    405.3 Adult VirginFemale Spermatheca    452.8 Adult InseminatedFemale Spermatheca    689.5 Adult Ovary    1305.7 Adult Testis    272 Adult Male Accessory Gland    1739.2 Adult Carcass    389.2 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    311.7   NA  Eye    201.65   NA  Brain    238.4   834.825  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    206.4   NA  Crop    459.7   710  Midgut    753.5   929  Hindgut    365.9   818.5  Malpighian Tubules    532.3   1061.2  Fat Body    747.7   3011.3  Salivary Gland    1610.7   NA  Heart    405.3   1258.125  Trachea    NA   NA  VirginFemale Spermatheca    452.8   NA  InseminatedFemale Spermatheca    689.5   NA  Ovary    1305.7   NA  Testis    272   NA  Male Accessory Gland    1739.2   1355.3  Carcass    389.2 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    132 central nervous system, larvae L3    101 central nervous system, pupae P8    60 head, virgin 1-day female    79 head, virgin 4-day female    44 head, virgin 20-day female    50 head, mated 1-day female    44 head, mated 4-day female    65 head, mated 20-day female    44 head, mated 1-day male    24 head, mated 4-day male    40 head, mated 20-day male    45 salivary gland, larvae L3 wandering    38 salivary gland, white prepupae    127 digestive system, larvae L3 wandering    56 digestive system, 1-day adult    62 digestive system, 4-day adult    84 digestive system, 20-day adult    56 fat body, larvae L3 wandering    67 fat body, white prepupae    67 fat body, pupae P8    46 carcass, larvae L3 wandering    136 carcass, 1-day adult    45 carcass, 4-day adult    82 carcass, 20-day adult    45 ovary, virgin 4-day female    235 ovary, mated 4-day female    191 testis, mated 4-day male    46 accessory gland, mated 4-day male    60 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (132) central nervous system, larvae L3  (101) central nervous system, pupae P8  (60) head, virgin 1-day female  (79) head, virgin 4-day female  (44) head, virgin 20-day female  (50) head, mated 1-day female  (44) head, mated 4-day female  (65) head, mated 20-day female  (44) head, mated 1-day male    24 head, mated 4-day male  (40) head, mated 20-day male  (45) salivary gland, larvae L3 wandering  (38) salivary gland, white prepupae  (127) digestive system, larvae L3 wandering  (56) digestive system, 1-day adult  (62) digestive system, 4-day adult  (84) digestive system, 20-day adult  (56) fat body, larvae L3 wandering  (67) fat body, white prepupae  (67) fat body, pupae P8  (46) carcass, larvae L3 wandering  (136) carcass, 1-day adult  (45) carcass, 4-day adult  (82) carcass, 20-day adult  (45) ovary, virgin 4-day female  (235) ovary, mated 4-day female  (191) testis, mated 4-day male  (46) accessory gland, mated 4-day male  (60) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (132) central nervous system, larvae L3  101 central nervous system, pupae P8    60 head, virgin 1-day female    79 head, virgin 4-day female    44 head, virgin 20-day female    50 head, mated 1-day female    44 head, mated 4-day female    65 head, mated 20-day female    44 head, mated 1-day male    24 head, mated 4-day male    40 head, mated 20-day male    45 salivary gland, larvae L3 wandering    38 salivary gland, white prepupae  (127) digestive system, larvae L3 wandering    56 digestive system, 1-day adult    62 digestive system, 4-day adult    84 digestive system, 20-day adult    56 fat body, larvae L3 wandering    67 fat body, white prepupae    67 fat body, pupae P8    46 carcass, larvae L3 wandering  (136) carcass, 1-day adult    45 carcass, 4-day adult    82 carcass, 20-day adult    45 ovary, virgin 4-day female  (235) ovary, mated 4-day female  (191) testis, mated 4-day male    46 accessory gland, mated 4-day male    60 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    132 central nervous system, larvae L3    101 central nervous system, pupae P8    60 head, virgin 1-day female    79 head, virgin 4-day female    44 head, virgin 20-day female    50 head, mated 1-day female    44 head, mated 4-day female    65 head, mated 20-day female    44 head, mated 1-day male    24 head, mated 4-day male    40 head, mated 20-day male    45 salivary gland, larvae L3 wandering    38 salivary gland, white prepupae    127 digestive system, larvae L3 wandering    56 digestive system, 1-day adult    62 digestive system, 4-day adult    84 digestive system, 20-day adult    56 fat body, larvae L3 wandering    67 fat body, white prepupae    67 fat body, pupae P8    46 carcass, larvae L3 wandering    136 carcass, 1-day adult    45 carcass, 4-day adult    82 carcass, 20-day adult    45 ovary, virgin 4-day female    235 ovary, mated 4-day female    191 testis, mated 4-day male    46 accessory gland, mated 4-day male    60 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    132 central nervous system, larvae L3    101 central nervous system, pupae P8    60 head, virgin 1-day female    79 head, virgin 4-day female    44 head, virgin 20-day female    50 head, mated 1-day female    44 head, mated 4-day female    65 head, mated 20-day female    44 head, mated 1-day male    24 head, mated 4-day male    40 head, mated 20-day male    45 salivary gland, larvae L3 wandering    38 salivary gland, white prepupae    127 digestive system, larvae L3 wandering    56 digestive system, 1-day adult    62 digestive system, 4-day adult    84 digestive system, 20-day adult    56 fat body, larvae L3 wandering    67 fat body, white prepupae    67 fat body, pupae P8    46 carcass, larvae L3 wandering    136 carcass, 1-day adult    45 carcass, 4-day adult    82 carcass, 20-day adult    45 ovary, virgin 4-day female    235 ovary, mated 4-day female    191 testis, mated 4-day male    46 accessory gland, mated 4-day male    60 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (132) central nervous system, larvae L3  (101) central nervous system, pupae P8  (60) head, virgin 1-day female  (79) head, virgin 4-day female  (44) head, virgin 20-day female  (50) head, mated 1-day female  (44) head, mated 4-day female  (65) head, mated 20-day female  (44) head, mated 1-day male    24 head, mated 4-day male  (40) head, mated 20-day male  (45) salivary gland, larvae L3 wandering  (38) salivary gland, white prepupae  (127) digestive system, larvae L3 wandering  (56) digestive system, 1-day adult  (62) digestive system, 4-day adult  (84) digestive system, 20-day adult  (56) fat body, larvae L3 wandering  (67) fat body, white prepupae  (67) fat body, pupae P8  (46) carcass, larvae L3 wandering  (136) carcass, 1-day adult  (45) carcass, 4-day adult  (82) carcass, 20-day adult  (45) ovary, virgin 4-day female  (235) ovary, mated 4-day female  (191) testis, mated 4-day male  (46) accessory gland, mated 4-day male  (60) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering  132 central nervous system, larvae L3  101 central nervous system, pupae P8    60 head, virgin 1-day female    79 head, virgin 4-day female    44 head, virgin 20-day female    50 head, mated 1-day female    44 head, mated 4-day female    65 head, mated 20-day female    44 head, mated 1-day male    24 head, mated 4-day male    40 head, mated 20-day male    45 salivary gland, larvae L3 wandering    38 salivary gland, white prepupae  127 digestive system, larvae L3 wandering    56 digestive system, 1-day adult    62 digestive system, 4-day adult    84 digestive system, 20-day adult    56 fat body, larvae L3 wandering    67 fat body, white prepupae    67 fat body, pupae P8    46 carcass, larvae L3 wandering  136 carcass, 1-day adult    45 carcass, 4-day adult    82 carcass, 20-day adult    45 ovary, virgin 4-day female  (235) ovary, mated 4-day female  (191) testis, mated 4-day male    46 accessory gland, mated 4-day male    60 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    132 central nervous system, larvae L3    101 central nervous system, pupae P8    60 head, virgin 1-day female    79 head, virgin 4-day female    44 head, virgin 20-day female    50 head, mated 1-day female    44 head, mated 4-day female    65 head, mated 20-day female    44 head, mated 1-day male    24 head, mated 4-day male    40 head, mated 20-day male    45 salivary gland, larvae L3 wandering    38 salivary gland, white prepupae    127 digestive system, larvae L3 wandering    56 digestive system, 1-day adult    62 digestive system, 4-day adult    84 digestive system, 20-day adult    56 fat body, larvae L3 wandering    67 fat body, white prepupae    67 fat body, pupae P8    46 carcass, larvae L3 wandering    136 carcass, 1-day adult    45 carcass, 4-day adult    82 carcass, 20-day adult    45 ovary, virgin 4-day female    235 ovary, mated 4-day female    191 testis, mated 4-day male    46 accessory gland, mated 4-day male    60 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression. Peak expression observed within 00-18 hour embryonic stages, during early larval stages, during early pupal stages, in adult female stages. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    219 embryo 02-04hr    260 embryo 04-06hr    209 embryo 06-08hr    199 embryo 08-10hr    230 embryo 10-12hr    219 embryo 12-14hr    215 embryo 14-16hr    198 embryo 16-18hr    136 embryo 18-20hr    74 embryo 20-22hr    83 embryo 22-24hr    95 larva L1    180 larva L2    267 larva L3 12hr old    180 larva L3 puffstage 1-2    91 larva L3 puffstage 3-6    93 larva L3 puffstage 7-9    113 white prepupae new    133 white prepupae 12hr    68 white prepupae 24hr    103 pupae 2d postWPP    121 pupae 3d postWPP    53 pupae 4d postWPP    37 adult male 01day    51 adult male 05day    49 adult male 30day    49 adult female 01day    138 adult female 05day    211 adult female 30day    190 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (219) embryo 02-04hr  (260) embryo 04-06hr  (209) embryo 06-08hr  (199) embryo 08-10hr  (230) embryo 10-12hr  (219) embryo 12-14hr  (215) embryo 14-16hr  (198) embryo 16-18hr  (136) embryo 18-20hr  (74) embryo 20-22hr  (83) embryo 22-24hr  (95) larva L1  (180) larva L2  (267) larva L3 12hr old  (180) larva L3 puffstage 1-2  (91) larva L3 puffstage 3-6  (93) larva L3 puffstage 7-9  (113) white prepupae new  (133) white prepupae 12hr  (68) white prepupae 24hr  (103) pupae 2d postWPP  (121) pupae 3d postWPP  (53) pupae 4d postWPP  (37) adult male 01day  (51) adult male 05day  (49) adult male 30day  (49) adult female 01day  (138) adult female 05day  (211) adult female 30day  (190) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr  (219) embryo 02-04hr  (260) embryo 04-06hr  (209) embryo 06-08hr  (199) embryo 08-10hr  (230) embryo 10-12hr  (219) embryo 12-14hr  (215) embryo 14-16hr  (198) embryo 16-18hr  (136) embryo 18-20hr    74 embryo 20-22hr    83 embryo 22-24hr    95 larva L1  (180) larva L2  (267) larva L3 12hr old  (180) larva L3 puffstage 1-2    91 larva L3 puffstage 3-6    93 larva L3 puffstage 7-9  (113) white prepupae new  (133) white prepupae 12hr    68 white prepupae 24hr  103 pupae 2d postWPP  (121) pupae 3d postWPP    53 pupae 4d postWPP    37 adult male 01day    51 adult male 05day    49 adult male 30day    49 adult female 01day  (138) adult female 05day  (211) adult female 30day  (190) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    219 embryo 02-04hr    260 embryo 04-06hr    209 embryo 06-08hr    199 embryo 08-10hr    230 embryo 10-12hr    219 embryo 12-14hr    215 embryo 14-16hr    198 embryo 16-18hr    136 embryo 18-20hr    74 embryo 20-22hr    83 embryo 22-24hr    95 larva L1    180 larva L2    267 larva L3 12hr old    180 larva L3 puffstage 1-2    91 larva L3 puffstage 3-6    93 larva L3 puffstage 7-9    113 white prepupae new    133 white prepupae 12hr    68 white prepupae 24hr    103 pupae 2d postWPP    121 pupae 3d postWPP    53 pupae 4d postWPP    37 adult male 01day    51 adult male 05day    49 adult male 30day    49 adult female 01day    138 adult female 05day    211 adult female 30day    190 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    219 embryo 02-04hr    260 embryo 04-06hr    209 embryo 06-08hr    199 embryo 08-10hr    230 embryo 10-12hr    219 embryo 12-14hr    215 embryo 14-16hr    198 embryo 16-18hr    136 embryo 18-20hr    74 embryo 20-22hr    83 embryo 22-24hr    95 larva L1    180 larva L2    267 larva L3 12hr old    180 larva L3 puffstage 1-2    91 larva L3 puffstage 3-6    93 larva L3 puffstage 7-9    113 white prepupae new    133 white prepupae 12hr    68 white prepupae 24hr    103 pupae 2d postWPP    121 pupae 3d postWPP    53 pupae 4d postWPP    37 adult male 01day    51 adult male 05day    49 adult male 30day    49 adult female 01day    138 adult female 05day    211 adult female 30day    190 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (219) embryo 02-04hr  (260) embryo 04-06hr  (209) embryo 06-08hr  (199) embryo 08-10hr  (230) embryo 10-12hr  (219) embryo 12-14hr  (215) embryo 14-16hr  (198) embryo 16-18hr  (136) embryo 18-20hr  (74) embryo 20-22hr  (83) embryo 22-24hr  (95) larva L1  (180) larva L2  (267) larva L3 12hr old  (180) larva L3 puffstage 1-2  (91) larva L3 puffstage 3-6  (93) larva L3 puffstage 7-9  (113) white prepupae new  (133) white prepupae 12hr  (68) white prepupae 24hr  (103) pupae 2d postWPP  (121) pupae 3d postWPP  (53) pupae 4d postWPP  (37) adult male 01day  (51) adult male 05day  (49) adult male 30day  (49) adult female 01day  (138) adult female 05day  (211) adult female 30day  (190) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr  (219) embryo 02-04hr  (260) embryo 04-06hr  (209) embryo 06-08hr  (199) embryo 08-10hr  (230) embryo 10-12hr  (219) embryo 12-14hr  (215) embryo 14-16hr  (198) embryo 16-18hr  136 embryo 18-20hr    74 embryo 20-22hr    83 embryo 22-24hr    95 larva L1  (180) larva L2  (267) larva L3 12hr old  (180) larva L3 puffstage 1-2    91 larva L3 puffstage 3-6    93 larva L3 puffstage 7-9  113 white prepupae new  133 white prepupae 12hr    68 white prepupae 24hr  103 pupae 2d postWPP  121 pupae 3d postWPP    53 pupae 4d postWPP    37 adult male 01day    51 adult male 05day    49 adult male 30day    49 adult female 01day  138 adult female 05day  (211) adult female 30day  (190) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    219 embryo 02-04hr    260 embryo 04-06hr    209 embryo 06-08hr    199 embryo 08-10hr    230 embryo 10-12hr    219 embryo 12-14hr    215 embryo 14-16hr    198 embryo 16-18hr    136 embryo 18-20hr    74 embryo 20-22hr    83 embryo 22-24hr    95 larva L1    180 larva L2    267 larva L3 12hr old    180 larva L3 puffstage 1-2    91 larva L3 puffstage 3-6    93 larva L3 puffstage 7-9    113 white prepupae new    133 white prepupae 12hr    68 white prepupae 24hr    103 pupae 2d postWPP    121 pupae 3d postWPP    53 pupae 4d postWPP    37 adult male 01day    51 adult male 05day    49 adult male 30day    49 adult female 01day    138 adult female 05day    211 adult female 30day    190 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    166 Schneider line 2 Sg4    210 embryonic 1182-4H    210 embryonic GM2    142 embryonic Kc167    71 embryonic S1    114 embryonic S3    265 leg disc CME L1    220 wing disc CME-W2    159 wing disc ML-DmD8    197 wing disc ML-DmD9    54 wing disc ML-DmD16-c3    177 wing disc ML-DmD21    77 wing disc ML-DmD32    94 haltere disc ML-DmD17-c3    90 eye-antennal disc ML-DmD11    147 antennal disc ML-DmD20-c5    265 mixed discs ML-DmD4-c1    192 CNS ML-DmBG1-c1    188 CNS ML-DmBG2-c2    71 tumorous blood cells mbn2    91 ovary fGS/OSS    71 ovary OSC    93 ovary OSS    42 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (166) Schneider line 2 Sg4  (210) embryonic 1182-4H  (210) embryonic GM2  (142) embryonic Kc167  (71) embryonic S1  (114) embryonic S3  (265) leg disc CME L1  (220) wing disc CME-W2  (159) wing disc ML-DmD8  (197) wing disc ML-DmD9  (54) wing disc ML-DmD16-c3  (177) wing disc ML-DmD21  (77) wing disc ML-DmD32  (94) haltere disc ML-DmD17-c3  (90) eye-antennal disc ML-DmD11  (147) antennal disc ML-DmD20-c5  (265) mixed discs ML-DmD4-c1  (192) CNS ML-DmBG1-c1  (188) CNS ML-DmBG2-c2  (71) tumorous blood cells mbn2  (91) ovary fGS/OSS  (71) ovary OSC  (93) ovary OSS  (42) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+  (166) Schneider line 2 Sg4  (210) embryonic 1182-4H  (210) embryonic GM2  (142) embryonic Kc167    71 embryonic S1  (114) embryonic S3  (265) leg disc CME L1  (220) wing disc CME-W2  (159) wing disc ML-DmD8  (197) wing disc ML-DmD9    54 wing disc ML-DmD16-c3  (177) wing disc ML-DmD21    77 wing disc ML-DmD32    94 haltere disc ML-DmD17-c3    90 eye-antennal disc ML-DmD11  (147) antennal disc ML-DmD20-c5  (265) mixed discs ML-DmD4-c1  (192) CNS ML-DmBG1-c1  (188) CNS ML-DmBG2-c2    71 tumorous blood cells mbn2    91 ovary fGS/OSS    71 ovary OSC    93 ovary OSS    42 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    166 Schneider line 2 Sg4    210 embryonic 1182-4H    210 embryonic GM2    142 embryonic Kc167    71 embryonic S1    114 embryonic S3    265 leg disc CME L1    220 wing disc CME-W2    159 wing disc ML-DmD8    197 wing disc ML-DmD9    54 wing disc ML-DmD16-c3    177 wing disc ML-DmD21    77 wing disc ML-DmD32    94 haltere disc ML-DmD17-c3    90 eye-antennal disc ML-DmD11    147 antennal disc ML-DmD20-c5    265 mixed discs ML-DmD4-c1    192 CNS ML-DmBG1-c1    188 CNS ML-DmBG2-c2    71 tumorous blood cells mbn2    91 ovary fGS/OSS    71 ovary OSC    93 ovary OSS    42 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    166 Schneider line 2 Sg4    210 embryonic 1182-4H    210 embryonic GM2    142 embryonic Kc167    71 embryonic S1    114 embryonic S3    265 leg disc CME L1    220 wing disc CME-W2    159 wing disc ML-DmD8    197 wing disc ML-DmD9    54 wing disc ML-DmD16-c3    177 wing disc ML-DmD21    77 wing disc ML-DmD32    94 haltere disc ML-DmD17-c3    90 eye-antennal disc ML-DmD11    147 antennal disc ML-DmD20-c5    265 mixed discs ML-DmD4-c1    192 CNS ML-DmBG1-c1    188 CNS ML-DmBG2-c2    71 tumorous blood cells mbn2    91 ovary fGS/OSS    71 ovary OSC    93 ovary OSS    42 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (166) Schneider line 2 Sg4  (210) embryonic 1182-4H  (210) embryonic GM2  (142) embryonic Kc167  (71) embryonic S1  (114) embryonic S3  (265) leg disc CME L1  (220) wing disc CME-W2  (159) wing disc ML-DmD8  (197) wing disc ML-DmD9  (54) wing disc ML-DmD16-c3  (177) wing disc ML-DmD21  (77) wing disc ML-DmD32  (94) haltere disc ML-DmD17-c3  (90) eye-antennal disc ML-DmD11  (147) antennal disc ML-DmD20-c5  (265) mixed discs ML-DmD4-c1  (192) CNS ML-DmBG1-c1  (188) CNS ML-DmBG2-c2  (71) tumorous blood cells mbn2  (91) ovary fGS/OSS  (71) ovary OSC  (93) ovary OSS  (42) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+  (166) Schneider line 2 Sg4  (210) embryonic 1182-4H  (210) embryonic GM2  142 embryonic Kc167    71 embryonic S1  114 embryonic S3  (265) leg disc CME L1  (220) wing disc CME-W2  (159) wing disc ML-DmD8  (197) wing disc ML-DmD9    54 wing disc ML-DmD16-c3  (177) wing disc ML-DmD21    77 wing disc ML-DmD32    94 haltere disc ML-DmD17-c3    90 eye-antennal disc ML-DmD11  (147) antennal disc ML-DmD20-c5  (265) mixed discs ML-DmD4-c1  (192) CNS ML-DmBG1-c1  (188) CNS ML-DmBG2-c2    71 tumorous blood cells mbn2    91 ovary fGS/OSS    71 ovary OSC    93 ovary OSS    42 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    166 Schneider line 2 Sg4    210 embryonic 1182-4H    210 embryonic GM2    142 embryonic Kc167    71 embryonic S1    114 embryonic S3    265 leg disc CME L1    220 wing disc CME-W2    159 wing disc ML-DmD8    197 wing disc ML-DmD9    54 wing disc ML-DmD16-c3    177 wing disc ML-DmD21    77 wing disc ML-DmD32    94 haltere disc ML-DmD17-c3    90 eye-antennal disc ML-DmD11    147 antennal disc ML-DmD20-c5    265 mixed discs ML-DmD4-c1    192 CNS ML-DmBG1-c1    188 CNS ML-DmBG2-c2    71 tumorous blood cells mbn2    91 ovary fGS/OSS    71 ovary OSC    93 ovary OSS    42 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    53 cold shock, 4-day adult    43 heat shock, 4-day adult    129 Cadmium 50 mM 6 hrs, larvae L3    103 Cadmium 50 mM 12 hrs, larvae L3    88 Cadmium 50 mM 48 hrs, 4-day adult    145 Cadmium 100 mM 48 hrs, 4-day adult    137 Copper 0.5 mM 12 hrs, larvae L3    58 Copper 15 mM 48 hrs, 4-day adult    109 Zinc 5 mM 12 hrs, larvae L3    60 Zinc 4.5 mM 48 hrs, 4-day adult    62 Ethanol 2.5% 3 hrs, larvae L3    137 Ethanol 5% 3 hrs, larvae L3    88 Ethanol 10% 3 hrs, larvae L3    110 Caffeine 1.5 mg/ml 4 hrs, larvae L3    56 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    123 Caffeine 25 mg/ml 48 hrs, 4-day adult    52 Paraquat 5 mM 48 hrs, 4-day adult    116 Paraquat 10 mM 48 hrs, 4-day adult    107 Rotenone 2 μg 12 hrs, larvae L3    113 Rotenone 8 μg 12 hrs, larvae L3    95 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult  (53) cold shock, 4-day adult  (43) heat shock, 4-day adult  (129) Cadmium 50 mM 6 hrs, larvae L3  (103) Cadmium 50 mM 12 hrs, larvae L3  (88) Cadmium 50 mM 48 hrs, 4-day adult  (145) Cadmium 100 mM 48 hrs, 4-day adult  (137) Copper 0.5 mM 12 hrs, larvae L3  (58) Copper 15 mM 48 hrs, 4-day adult  (109) Zinc 5 mM 12 hrs, larvae L3  (60) Zinc 4.5 mM 48 hrs, 4-day adult  (62) Ethanol 2.5% 3 hrs, larvae L3  (137) Ethanol 5% 3 hrs, larvae L3  (88) Ethanol 10% 3 hrs, larvae L3  (110) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (56) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (123) Caffeine 25 mg/ml 48 hrs, 4-day adult  (52) Paraquat 5 mM 48 hrs, 4-day adult  (116) Paraquat 10 mM 48 hrs, 4-day adult  (107) Rotenone 2 μg 12 hrs, larvae L3  (113) Rotenone 8 μg 12 hrs, larvae L3  (95) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    53 cold shock, 4-day adult    43 heat shock, 4-day adult  (129) Cadmium 50 mM 6 hrs, larvae L3  103 Cadmium 50 mM 12 hrs, larvae L3    88 Cadmium 50 mM 48 hrs, 4-day adult  (145) Cadmium 100 mM 48 hrs, 4-day adult  (137) Copper 0.5 mM 12 hrs, larvae L3    58 Copper 15 mM 48 hrs, 4-day adult  (109) Zinc 5 mM 12 hrs, larvae L3    60 Zinc 4.5 mM 48 hrs, 4-day adult    62 Ethanol 2.5% 3 hrs, larvae L3  (137) Ethanol 5% 3 hrs, larvae L3    88 Ethanol 10% 3 hrs, larvae L3  (110) Caffeine 1.5 mg/ml 4 hrs, larvae L3    56 Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (123) Caffeine 25 mg/ml 48 hrs, 4-day adult    52 Paraquat 5 mM 48 hrs, 4-day adult  (116) Paraquat 10 mM 48 hrs, 4-day adult  107 Rotenone 2 μg 12 hrs, larvae L3  (113) Rotenone 8 μg 12 hrs, larvae L3    95 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    53 cold shock, 4-day adult    43 heat shock, 4-day adult    129 Cadmium 50 mM 6 hrs, larvae L3    103 Cadmium 50 mM 12 hrs, larvae L3    88 Cadmium 50 mM 48 hrs, 4-day adult    145 Cadmium 100 mM 48 hrs, 4-day adult    137 Copper 0.5 mM 12 hrs, larvae L3    58 Copper 15 mM 48 hrs, 4-day adult    109 Zinc 5 mM 12 hrs, larvae L3    60 Zinc 4.5 mM 48 hrs, 4-day adult    62 Ethanol 2.5% 3 hrs, larvae L3    137 Ethanol 5% 3 hrs, larvae L3    88 Ethanol 10% 3 hrs, larvae L3    110 Caffeine 1.5 mg/ml 4 hrs, larvae L3    56 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    123 Caffeine 25 mg/ml 48 hrs, 4-day adult    52 Paraquat 5 mM 48 hrs, 4-day adult    116 Paraquat 10 mM 48 hrs, 4-day adult    107 Rotenone 2 μg 12 hrs, larvae L3    113 Rotenone 8 μg 12 hrs, larvae L3    95 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    53 cold shock, 4-day adult    43 heat shock, 4-day adult    129 Cadmium 50 mM 6 hrs, larvae L3    103 Cadmium 50 mM 12 hrs, larvae L3    88 Cadmium 50 mM 48 hrs, 4-day adult    145 Cadmium 100 mM 48 hrs, 4-day adult    137 Copper 0.5 mM 12 hrs, larvae L3    58 Copper 15 mM 48 hrs, 4-day adult    109 Zinc 5 mM 12 hrs, larvae L3    60 Zinc 4.5 mM 48 hrs, 4-day adult    62 Ethanol 2.5% 3 hrs, larvae L3    137 Ethanol 5% 3 hrs, larvae L3    88 Ethanol 10% 3 hrs, larvae L3    110 Caffeine 1.5 mg/ml 4 hrs, larvae L3    56 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    123 Caffeine 25 mg/ml 48 hrs, 4-day adult    52 Paraquat 5 mM 48 hrs, 4-day adult    116 Paraquat 10 mM 48 hrs, 4-day adult    107 Rotenone 2 μg 12 hrs, larvae L3    113 Rotenone 8 μg 12 hrs, larvae L3    95 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult  (53) cold shock, 4-day adult  (43) heat shock, 4-day adult  (129) Cadmium 50 mM 6 hrs, larvae L3  (103) Cadmium 50 mM 12 hrs, larvae L3  (88) Cadmium 50 mM 48 hrs, 4-day adult  (145) Cadmium 100 mM 48 hrs, 4-day adult  (137) Copper 0.5 mM 12 hrs, larvae L3  (58) Copper 15 mM 48 hrs, 4-day adult  (109) Zinc 5 mM 12 hrs, larvae L3  (60) Zinc 4.5 mM 48 hrs, 4-day adult  (62) Ethanol 2.5% 3 hrs, larvae L3  (137) Ethanol 5% 3 hrs, larvae L3  (88) Ethanol 10% 3 hrs, larvae L3  (110) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (56) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (123) Caffeine 25 mg/ml 48 hrs, 4-day adult  (52) Paraquat 5 mM 48 hrs, 4-day adult  (116) Paraquat 10 mM 48 hrs, 4-day adult  (107) Rotenone 2 μg 12 hrs, larvae L3  (113) Rotenone 8 μg 12 hrs, larvae L3  (95) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    53 cold shock, 4-day adult    43 heat shock, 4-day adult  129 Cadmium 50 mM 6 hrs, larvae L3  103 Cadmium 50 mM 12 hrs, larvae L3    88 Cadmium 50 mM 48 hrs, 4-day adult  (145) Cadmium 100 mM 48 hrs, 4-day adult  137 Copper 0.5 mM 12 hrs, larvae L3    58 Copper 15 mM 48 hrs, 4-day adult  109 Zinc 5 mM 12 hrs, larvae L3    60 Zinc 4.5 mM 48 hrs, 4-day adult    62 Ethanol 2.5% 3 hrs, larvae L3  137 Ethanol 5% 3 hrs, larvae L3    88 Ethanol 10% 3 hrs, larvae L3  110 Caffeine 1.5 mg/ml 4 hrs, larvae L3    56 Caffeine 2.5 mg/ml 48 hrs, 4-day adult  123 Caffeine 25 mg/ml 48 hrs, 4-day adult    52 Paraquat 5 mM 48 hrs, 4-day adult  116 Paraquat 10 mM 48 hrs, 4-day adult  107 Rotenone 2 μg 12 hrs, larvae L3  113 Rotenone 8 μg 12 hrs, larvae L3    95 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    53 cold shock, 4-day adult    43 heat shock, 4-day adult    129 Cadmium 50 mM 6 hrs, larvae L3    103 Cadmium 50 mM 12 hrs, larvae L3    88 Cadmium 50 mM 48 hrs, 4-day adult    145 Cadmium 100 mM 48 hrs, 4-day adult    137 Copper 0.5 mM 12 hrs, larvae L3    58 Copper 15 mM 48 hrs, 4-day adult    109 Zinc 5 mM 12 hrs, larvae L3    60 Zinc 4.5 mM 48 hrs, 4-day adult    62 Ethanol 2.5% 3 hrs, larvae L3    137 Ethanol 5% 3 hrs, larvae L3    88 Ethanol 10% 3 hrs, larvae L3    110 Caffeine 1.5 mg/ml 4 hrs, larvae L3    56 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    123 Caffeine 25 mg/ml 48 hrs, 4-day adult    52 Paraquat 5 mM 48 hrs, 4-day adult    116 Paraquat 10 mM 48 hrs, 4-day adult    107 Rotenone 2 μg 12 hrs, larvae L3    113 Rotenone 8 μg 12 hrs, larvae L3    95 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_03 mE1_20_mRNA_expression_cluster_10
External Data & Images
Linkouts	BDGP expression data • LD06532 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0035121 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG7008-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable Tudor-SNCC00737 Tudor-SNEY07875 viable, with Scer\GAL4pnr-MD237 Tudor-SNGD4264 Sterility Allele fertile Tudor-SNEY07875 Phenotype manifest in Allele
Classical Alleles ( 13 )
For All Classical Alleles Show
Allele of Tudor-SN Class Mutagen Stocks Known lesion Tudor-SNCB-5147-3 1 -- Tudor-SNCB-5221-3 1 -- Tudor-SNEY07875 P-element activity 1 -- Tudor-SNKG02565 P-element activity 1 -- Tudor-SN5-HA-2126 0 -- Tudor-SNCC00737 P-element activity 0 Yes Tudor-SNCPTI002221 piggyBac transposase 0 Yes Tudor-SNCPTI003391 piggyBac transposase 0 Yes Tudor-SNDG16311 P-element activity 0 -- Tudor-SNEP305 P-element activity 0 -- Tudor-SNEP3509 P-element activity 0 -- Tudor-SNEP889 P-element activity 0 -- Tudor-SNNP4692 0 --
Alleles Carried on Transgenic Constructs ( 5 )
For All Alleles Carried on Transgenic Constructs Show
Allele of Tudor-SN Class Mutagen Stocks Known lesion Tudor-SNGD4264 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes Tudor-SNHMS00184 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes Tudor-SNdsRNA.cDa in vitro construct - RNAi 0 Yes Tudor-SNdsRNA.shRNA.Scer\UAS.P\T in vitro construct - regulatory fusion in vitro construct - RNAi 0 Yes Tudor-SNScer\UAS.cDa in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(3L)Exel6084 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD4264} NA P{TRiP.HMS00184} NA P{UASp-Tudor-SN.shRNA} NA P{UAS-Tudor-SN.D} NA
Insertions
	Type of insertions Name Expression data insertion of mobile activating element P{EP}Tudor-SNEP305 NA P{EP}Tudor-SNEP889 NA P{EP}Tudor-SNEP3509 NA P{EPgy2}Tudor-SNEY07875 NA P{GSV1}C293C293 NA miscellaneous insertions P{PTT-GC}Tudor-SNCC00737 NA P{RS3}Tudor-SNCB-5147-3 NA P{RS3}Tudor-SNCB-5221-3 NA P{RS5}Tudor-SN5-HA-2126 NA P{SUPor-P}Tudor-SNKG02565 NA P{wHy}Tudor-SNDG16311 NA PBac{768.FSVS-0}Tudor-SNCPTI002221 NA PBac{CPTI-un}Tudor-SNCPTI003391 NA insertion of enhancer trap binary system P{GawB}Tudor-SNNP4692 No
Gene Ontology: Function, Process & Cellular Component ( 7 unique terms )
Terms Based on Experimental Evidence ( 2 terms )
Molecular Function ( 0 terms)
Biological Process ( 0 terms)
Cellular Component
CV term Evidence References
lipid particle inferred from direct assay (Beller et al., 2006) microtubule associated complex inferred from direct assay (Hughes et al., 2008)
Terms Based on Predictions or Assertions ( 5 terms )
Molecular Function
CV term Evidence References
hydrolase activity, acting on ester bonds inferred from electronic annotation with InterPro:IPR006021, InterPro:IPR016071 (FlyBase Curators et al., 2004-) nucleic acid binding inferred from electronic annotation with InterPro:IPR006021, InterPro:IPR016071 (FlyBase Curators et al., 2004-) transcription coactivator activity inferred from sequence or structural similarity with EMBL:U22055 (FlyBase, 1992-)
Biological Process
CV term Evidence References
gene silencing by RNA inferred from electronic annotation with InterPro:IPR016685 (FlyBase Curators et al., 2004-)
Cellular Component
CV term Evidence References
RNA-induced silencing complex inferred from electronic annotation with InterPro:IPR016685 (FlyBase Curators et al., 2004-) traceable author statement (Murchison and Hannon, 2004)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
protein-protein
Interacting group Assay References
Tudor-SN - Aats-his anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Tudor-SN - Arp2 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Tudor-SN - Arpc2 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Tudor-SN - Arpc3A anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Tudor-SN - CG13539 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Tudor-SN - CG14762 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Tudor-SN - CG18335 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Tudor-SN - CG2931 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Tudor-SN - CG7049 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Tudor-SN - Der-2 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Tudor-SN - Hop experimental knowledge based (Guruharsha et al., 2011) Tudor-SN - Moe experimental knowledge based (Guruharsha et al., 2011) Tudor-SN - cpb anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Tudor-SN - dgrn anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Tudor-SN - didum anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Tudor-SN - vkg anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23)
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions Tudor-SN allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 63603 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0035121 DroID - A comprehensive database of gene and protein interactions. • FBgn0035121 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 38045
Orthologs
OrthoDB Orthologs (43) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6QNNFK Dipteran inclusive ortholog search EOG6ZPF3B Insect inclusive ortholog search EOG6QJQH3 Arthropod inclusive ortholog search EOG6X3FG7 Metazoa inclusive ortholog search EOG6JMMGH
Orthologs in Drosophila Species (EOG6QNNFK)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\Tudor-SN     Drosophila simulans   Dsim\GD25717 Y   Drosophila sechellia   Dsec\GM14288 Y   Drosophila erecta   Dere\GG14673 Y   Drosophila yakuba   Dyak\GE21033 Y   Drosophila ananassae   Dana\GF24753 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA20026 Y   Drosophila persimilis   Dper\GL16097 Y   Drosophila willistoni   Dwil\GK17654 Y   Drosophila willistoni   Dwil\GK23451     Drosophila virilis   Dvir\GJ16044 Y   Drosophila mojavensis   Dmoj\GI12526 Y   Drosophila grimshawi   Dgri\GH15748 Y
Orthologs in non-Drosophila Dipterans (EOG6ZPF3B)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL000293   Anopheles gambiae Malaria mosquito  Agam\AGAP005672   Anopheles gambiae Malaria mosquito  Agam\AGAP012831   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ006932
Orthologs in non-Dipteran Insects (EOG6QJQH3)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\Tudor-SN   Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG020143   Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH14151   Atta cephalotes Leafcutter ant  Acep\ACEP27196   Camponotus floridanus Florida carpenter ant  Cflo\CFLO22850   Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL14246   Linepithema humile Argentine ant  Lhum\LH15147   Pogonomyrmex barbatus Red harvester ant  Pbar\PB17591   Acyrthosiphon pisum Pea aphid  Apim\ACYPI004439   Acyrthosiphon pisum Pea aphid  Apim\ACYPI009925   Acyrthosiphon pisum Pea aphid  Apim\ACYPI006726   Acyrthosiphon pisum Pea aphid  Apim\ACYPI28903   Bombyx mori Silkmoth  Bmor\BGIBMGA013328   Pediculus humanus Human body louse  Phum\PHUM022440   Tribolium castaneum Red flour beetle  Tcas\TC002936
Orthologs in non-Insect Arthropods (EOG6X3FG7)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\Rnase10   Ixodes scapularis Deer tick  Isca\ISCW014289
Orthologs in non-Arthropod Metazoa (EOG6JMMGH)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Caenorhabditis elegans Nematode  Cele\tsn-1   Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_018440gn   Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_018441gn   Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_027855gn   Danio rerio Zebrafish  Drer\snd1   Xenopus tropicalis Western clawed frog  Xtro\snd1   Mus musculus House mouse  Mmus\Snd1   Rattus norvegicus Norway rat  Rnor\ENSRNOG00000031173   Homo sapiens Human  Hsap\SND1
Human Orthologs (1)
Gene OMIM HGNC Hsap\SND1
AAA Orthologs (11) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD25717 Drosophila sechellia Dsec\GM14288 Drosophila erecta Dere\GG14673 Drosophila yakuba Dyak\GE21033 Drosophila ananassae Dana\GF24753 Drosophila pseudoobscura pseudoobscura Dpse\GA20026 Drosophila persimilis Dper\GL16097 Drosophila willistoni Dwil\GK17654 Drosophila virilis Dvir\GJ16044 Drosophila mojavensis Dmoj\GI12526 Drosophila grimshawi Dgri\GH15748
Stocks & Reagents
Stocks Listed in FlyBase ( 6 )
Bloomington	17412 y1 w67c23; P{EPgy2}Tudor-SNEY07875 34865 y1 sc* v1; P{TRiP.HMS00184}attP2/TM3, Sb1 13757 y1 w67c23; P{SUPor-P}Tudor-SNKG02565 ry506
Kyoto	123485 w1118; P{RS3}Tudor-SNCB-5147-3 123514 w1118; P{RS3}Tudor-SNCB-5221-3
VDRC	v19011 w1118; P{GD4264}v19011/CyO
Genomic Clones ( 2 )
	BACR11J11 BACR13F06 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 112 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	LD06532 LD20211
Other clones	DPiM_LD20211
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT24762 GM02888 HL05771 LD02178 LD03781 LD05529 LD06852 LD08329 LD10180 LD10266 LD11941 LD13845 LD17120 LD19422 LD19626 LD19794 LD19796 LD30025 LD34390 LD34907 LD38220 LP21368 RE13912 RE25819 RE27877 RE28545 RE30614 RE31355 RE35950 RE36245 RE36973 RE37306 RE37401 RE37530 RE38205 RE39178 RE40847 RE41237 RE46869 RE46965 RE48026 RE48361 RE49463 RE51363 RE52774 RE62077 RE67052 RE67087 RE68728 RE70668 RE70956 RE74558 RE74777 SD06631 SD14121 SD23681
Other clones	2000 8033 10184 11546 44357 54203 56582 100670 100826 103891 106068 120764 144858 149694 160001 160473 163568 166609 192341 274777 280465 CK01.2C.A4 CK01.68C.D6 Dmel_dig_019161_0641_1786 Dmel_neb_014429_0444_1168 Dmel_neb_015482_0369_1390 EC26822 EC28706 EC051262 EK007126 EK010508 EK054947 EK106337 EK109823 EK111458 EK135337 EK140502 EK159627 EK173701 EK179364 EK223219 EK223429 EK231358 EK240938 EK252022 EK263210 EK267856 EK271241 EK302538 EK305342 FGM217C11 FGX001G02 UUGC0834
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0035121 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 38045
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments	snoRNA:Tudor-SN-a is encoded in an intron of Tudor-SN. (Graveley et al., 2011)
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_138177 NM_001274266 RefSeq (Proteins) • NP_612021 NP_001261195 DDBJ / EMBL / GenBank • AA263398 AA540503 AAF47366 AAL39506 AAO25027 AGB93890 AQ025060 AQ254665 AQ254725 AW941619 AY069361 BH634797 BH759351 BT003270 CL525966 Entrez Gene - A searchable database of RefSeq genes. • 38045 UniProtKB/TrEMBL • Q8T0F1 Q9W0S7
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Tudor domain (IPR002999) Staphylococcal nuclease (SNase-like) (IPR006021) Staphylococcal nuclease (SNase-like), OB-fold (IPR016071) RNA-induced silencing complex, nuclease component Tudor-SN (IPR016685) BDGP expression data - Patterns of gene expression in Drosophila embryogenesis • LD06532
Linkouts
	BioGRID - A database of protein and genetic interactions • 63603 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0035121 DroID - A comprehensive database of gene and protein interactions. • FBgn0035121 DRSC - Results from RNAi screens. • FBgn0035121 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0035121 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG7008-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0035121 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 38045 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 38045 modMine - Data generated by the modENCODE project. • FBgn0035121
Synonyms & Secondary IDs ( 10 )
Reported As
Symbol Synonym	CG7008 (Giot et al., 2003, Huang et al., 2005, Molnar et al., 2006, O'Keefe et al., 2011, Gim et al., 2001, Hughes et al., 2008, Ni et al., 2011.7.19, Cammarato et al., 2011) dP100 (Gim et al., 2001) p100 (Friberg et al., 2009) SND1 (Friberg et al., 2009) TSN (Tomari, 2005, Pham et al., 2004, Kim et al., 2007) TSN-1 (Murchison and Hannon, 2004) Tudor-SN (Beller et al., 2006, Dorner et al., 2006, Englund et al., 2006, Buszczak et al., 2007, Molnar et al., 2006, Friberg et al., 2009, O'Keefe et al., 2011, Carpenter et al., 2009, Friberg et al., 2010) tudor-SN (Dietzl et al., 2007, Graveley et al., 2011) TUDOR-SN (Kolaczkowski et al., 2011) tudor staphylococcus/micrococcal nuclease (Caudy et al., 2003)
Name Synonym	Tudor-SN (Graveley et al., 2011, Cammarato et al., 2011, Handler et al., 2011)
Secondary FlyBase IDs
References ( 49 )
Generate a list of	All references relating to this gene ( 49 )
List References by type	Research paper  ( 19 ) Supplementary material  ( 8 ) Review  ( 4 ) Personal communication to FlyBase  ( 11 ) FlyBase analysis  ( 2 ) Website  ( 1 ) Curated genome annotation  ( 2 ) DNA/RNA sequence record  ( 1 )
Recent research papers ( 4 )
	Graveley et al., 2011, Nature 471(7339): 473--479 The developmental transcriptome of Drosophila melanogaster. [FBrf0213330] Handler et al., 2011, EMBO J. 30(19): 3977--3993 A systematic analysis of Drosophila TUDOR domain-containing proteins identifies Vreteno and the Tdrd12 family as essential primary piRNA pathway factors. [FBrf0216344] Kolaczkowski et al., 2011, Mol. Biol. Evol. 28(2): 1033--1042 Recurrent adaptation in RNA interference genes across the Drosophila phylogeny. [FBrf0212798] O'Keefe et al., 2011, Hum. Mol. Genet. 20(3): 497--509 Drosophila orthologue of WWOX, the chromosomal fragile site FRA16D tumour suppressor gene, functions in aerobic metabolism and regulates reactive oxygen species. [FBrf0212691] Show all research papers ...
Recent reviews (0)
	All reviews listed in FlyBase were published before 2011 Show reviews ...