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Gene Dmel\CG13895

General Information
Symbol	Dmel\CG13895	Species	D. melanogaster
Name		Annotation symbol	CG13895
Feature type	protein_coding_gene	FlyBase ID	FBgn0035158
Gene Model Status	Current	Stock availability	7 publicly available
Genomic Location
Chromosome (arm)	3L	Recombination map
Cytogenetic map	61C8-61C8	Sequence location	3L:705,945..708,201 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG13895 (FBgn0035158). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function: DNA binding. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: regulation of transcription, DNA-dependent. 14 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Centromere protein Cenp-B, DNA-binding domain 1; Helix-turn-helix, Psq-like; Homeodomain-like; Homeodomain-related; Pogo transposase / Cenp-B / PDC2, DNA-binding HTH domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 00-18 hour embryonic stages. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: larval central nervous system. Comments on Affy2 ProbeSet: ProbeSet 1629940_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG13895. Gene sequence location is 3L:705945..708201.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2011_10
FB2012_01	Sequence features BKN23514 HFA08365
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 61C8-61C8   Limits computationally determined from genome sequence between P{PZ}l(3)0596705967 and P{PZ}l(3)0264002640
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG13895 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG13895-RA FBtr0072605  NM_138211   1923   499
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG13895-PA   FBpp0072501   58.2   499   6.14     NP_612055   AAF47409
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Pogo transposase / Cenp-B / PDC2, DNA-binding HTH domain (IPR006600) Centromere protein Cenp-B, DNA-binding domain 1 (IPR006695) Homeodomain-like (IPR009057) Helix-turn-helix, Psq-like (IPR011526) Homeodomain-related (IPR012287)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE014296 AAF47409   AQ073102   AY071568 AAL49190   BI228551   BI242361   BI375386   BT056233   CO189927   CO265349   CO331227   CZ470046   CZ473606   CZ473607   CZ476659   CZ476660   CZ490094   EC057941   EC084263   EC090537   FD586539   FD586875   GH740409   GH742447   GH745656   GH747551   GH763733   GH764047   GH765672   GH767237   GH767441   GH767530   GH779384   GH779806   GH779830
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q8SYG6 Q9W0N4
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0035158    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0035158 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 00-18 hour embryonic stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0035158 expression level Developmental Stage   Expression Level embryo 00-02hr    572 embryo 02-04hr    698 embryo 04-06hr    2053 embryo 06-08hr    3003 embryo 08-10hr    2801 embryo 10-12hr    2092 embryo 12-14hr    1484 embryo 14-16hr    940 embryo 16-18hr    1118 embryo 18-20hr    953 embryo 20-22hr    748 embryo 22-24hr    955 larva L1    817 larva L2    324 larva L3 12hr old    289 larva L3 puffstage 1-2    407 larva L3 puffstage 3-6    578 larva L3 puffstage 7-9    673 white prepupae new    769 white prepupae 12hr    831 white prepupae 24hr    948 pupae 2d postWPP    825 pupae 3d postWPP    560 pupae 4d postWPP    422 adult male 01day    294 adult male 05day    308 adult male 30day    351 adult female 01day    448 adult female 05day    503 adult female 30day    485 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (572) embryo 02-04hr  (698) embryo 04-06hr  (2053) embryo 06-08hr  (3003) embryo 08-10hr  (2801) embryo 10-12hr  (2092) embryo 12-14hr  (1484) embryo 14-16hr  (940) embryo 16-18hr  (1118) embryo 18-20hr  (953) embryo 20-22hr  (748) embryo 22-24hr  (955) larva L1  (817) larva L2  (324) larva L3 12hr old  (289) larva L3 puffstage 1-2  (407) larva L3 puffstage 3-6  (578) larva L3 puffstage 7-9  (673) white prepupae new  (769) white prepupae 12hr  (831) white prepupae 24hr  (948) pupae 2d postWPP  (825) pupae 3d postWPP  (560) pupae 4d postWPP  (422) adult male 01day  (294) adult male 05day  (308) adult male 30day  (351) adult female 01day  (448) adult female 05day  (503) adult female 30day  (485) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    572 embryo 02-04hr    698 embryo 04-06hr  (2053) embryo 06-08hr  (3003) embryo 08-10hr  (2801) embryo 10-12hr  (2092) embryo 12-14hr  1484 embryo 14-16hr    940 embryo 16-18hr    1118 embryo 18-20hr    953 embryo 20-22hr    748 embryo 22-24hr    955 larva L1    817 larva L2    324 larva L3 12hr old    289 larva L3 puffstage 1-2    407 larva L3 puffstage 3-6    578 larva L3 puffstage 7-9    673 white prepupae new    769 white prepupae 12hr    831 white prepupae 24hr    948 pupae 2d postWPP    825 pupae 3d postWPP    560 pupae 4d postWPP    422 adult male 01day    294 adult male 05day    308 adult male 30day    351 adult female 01day    448 adult female 05day    503 adult female 30day    485 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    572 embryo 02-04hr    698 embryo 04-06hr    2053 embryo 06-08hr    3003 embryo 08-10hr    2801 embryo 10-12hr    2092 embryo 12-14hr    1484 embryo 14-16hr    940 embryo 16-18hr    1118 embryo 18-20hr    953 embryo 20-22hr    748 embryo 22-24hr    955 larva L1    817 larva L2    324 larva L3 12hr old    289 larva L3 puffstage 1-2    407 larva L3 puffstage 3-6    578 larva L3 puffstage 7-9    673 white prepupae new    769 white prepupae 12hr    831 white prepupae 24hr    948 pupae 2d postWPP    825 pupae 3d postWPP    560 pupae 4d postWPP    422 adult male 01day    294 adult male 05day    308 adult male 30day    351 adult female 01day    448 adult female 05day    503 adult female 30day    485 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    572 embryo 02-04hr    698 embryo 04-06hr    2053 embryo 06-08hr    3003 embryo 08-10hr    2801 embryo 10-12hr    2092 embryo 12-14hr    1484 embryo 14-16hr    940 embryo 16-18hr    1118 embryo 18-20hr    953 embryo 20-22hr    748 embryo 22-24hr    955 larva L1    817 larva L2    324 larva L3 12hr old    289 larva L3 puffstage 1-2    407 larva L3 puffstage 3-6    578 larva L3 puffstage 7-9    673 white prepupae new    769 white prepupae 12hr    831 white prepupae 24hr    948 pupae 2d postWPP    825 pupae 3d postWPP    560 pupae 4d postWPP    422 adult male 01day    294 adult male 05day    308 adult male 30day    351 adult female 01day    448 adult female 05day    503 adult female 30day    485 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0035158 expression level Developmental Stage   Expression Level embryo 00-02hr    572 embryo 02-04hr    698 embryo 04-06hr    2053 embryo 06-08hr    3003 embryo 08-10hr    2801 embryo 10-12hr    2092 embryo 12-14hr    1484 embryo 14-16hr    940 embryo 16-18hr    1118 embryo 18-20hr    953 embryo 20-22hr    748 embryo 22-24hr    955 larva L1    817 larva L2    324 larva L3 12hr old    289 larva L3 puffstage 1-2    407 larva L3 puffstage 3-6    578 larva L3 puffstage 7-9    673 white prepupae new    769 white prepupae 12hr    831 white prepupae 24hr    948 pupae 2d postWPP    825 pupae 3d postWPP    560 pupae 4d postWPP    422 adult male 01day    294 adult male 05day    308 adult male 30day    351 adult female 01day    448 adult female 05day    503 adult female 30day    485 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (572) embryo 02-04hr  (698) embryo 04-06hr  (2053) embryo 06-08hr  (3003) embryo 08-10hr  (2801) embryo 10-12hr  (2092) embryo 12-14hr  (1484) embryo 14-16hr  (940) embryo 16-18hr  (1118) embryo 18-20hr  (953) embryo 20-22hr  (748) embryo 22-24hr  (955) larva L1  (817) larva L2  (324) larva L3 12hr old  (289) larva L3 puffstage 1-2  (407) larva L3 puffstage 3-6  (578) larva L3 puffstage 7-9  (673) white prepupae new  (769) white prepupae 12hr  (831) white prepupae 24hr  (948) pupae 2d postWPP  (825) pupae 3d postWPP  (560) pupae 4d postWPP  (422) adult male 01day  (294) adult male 05day  (308) adult male 30day  (351) adult female 01day  (448) adult female 05day  (503) adult female 30day  (485) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    572 embryo 02-04hr    698 embryo 04-06hr  2053 embryo 06-08hr  (3003) embryo 08-10hr  (2801) embryo 10-12hr  2092 embryo 12-14hr  1484 embryo 14-16hr    940 embryo 16-18hr    1118 embryo 18-20hr    953 embryo 20-22hr    748 embryo 22-24hr    955 larva L1    817 larva L2    324 larva L3 12hr old    289 larva L3 puffstage 1-2    407 larva L3 puffstage 3-6    578 larva L3 puffstage 7-9    673 white prepupae new    769 white prepupae 12hr    831 white prepupae 24hr    948 pupae 2d postWPP    825 pupae 3d postWPP    560 pupae 4d postWPP    422 adult male 01day    294 adult male 05day    308 adult male 30day    351 adult female 01day    448 adult female 05day    503 adult female 30day    485 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    572 embryo 02-04hr    698 embryo 04-06hr    2053 embryo 06-08hr    3003 embryo 08-10hr    2801 embryo 10-12hr    2092 embryo 12-14hr    1484 embryo 14-16hr    940 embryo 16-18hr    1118 embryo 18-20hr    953 embryo 20-22hr    748 embryo 22-24hr    955 larva L1    817 larva L2    324 larva L3 12hr old    289 larva L3 puffstage 1-2    407 larva L3 puffstage 3-6    578 larva L3 puffstage 7-9    673 white prepupae new    769 white prepupae 12hr    831 white prepupae 24hr    948 pupae 2d postWPP    825 pupae 3d postWPP    560 pupae 4d postWPP    422 adult male 01day    294 adult male 05day    308 adult male 30day    351 adult female 01day    448 adult female 05day    503 adult female 30day    485 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    572 embryo 02-04hr    698 embryo 04-06hr    2053 embryo 06-08hr    3003 embryo 08-10hr    2801 embryo 10-12hr    2092 embryo 12-14hr    1484 embryo 14-16hr    940 embryo 16-18hr    1118 embryo 18-20hr    953 embryo 20-22hr    748 embryo 22-24hr    955 larva L1    817 larva L2    324 larva L3 12hr old    289 larva L3 puffstage 1-2    407 larva L3 puffstage 3-6    578 larva L3 puffstage 7-9    673 white prepupae new    769 white prepupae 12hr    831 white prepupae 24hr    948 pupae 2d postWPP    825 pupae 3d postWPP    560 pupae 4d postWPP    422 adult male 01day    294 adult male 05day    308 adult male 30day    351 adult female 01day    448 adult female 05day    503 adult female 30day    485 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0035158    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0035158 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: larval central nervous system. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0035158 expression level Tissue   Expression Level Larval Central Nervous System    115.35 Larval Midgut no informative data Larval Hindgut    74.2 Larval Malpighian Tubules    33.6 Larval Fat Body no informative data Larval Salivary Gland no informative data Larval Trachea    94.9 Larval Carcass    55.45 Adult Head    44.3 Adult Eye    56.975 Adult Brain    78.4 Adult Thoracic-Abdominal Ganglion    58.8 Adult Crop    65.4 Adult Midgut no informative data Adult Hindgut    56 Adult Malpighian Tubules    35.7 Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart    37.225 Adult VirginFemale Spermatheca    45.5 Adult InseminatedFemale Spermatheca    45.6 Adult Ovary    46.2 Adult Testis    9.7 Adult Male Accessory Gland no informative data Adult Carcass no informative data Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    115.35 Larval Midgut no informative data Larval Hindgut    74.2 Larval Malpighian Tubules    33.6 Larval Fat Body no informative data Larval Salivary Gland no informative data Larval Trachea    94.9 Larval Carcass    55.45 Adult Head    44.3 Adult Eye    56.975 Adult Brain    78.4 Adult Thoracic-Abdominal Ganglion    58.8 Adult Crop    65.4 Adult Midgut no informative data Adult Hindgut    56 Adult Malpighian Tubules    35.7 Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart    37.225 Adult VirginFemale Spermatheca    45.5 Adult InseminatedFemale Spermatheca    45.6 Adult Ovary    46.2 Adult Testis    9.7 Adult Male Accessory Gland no informative data Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    115.35 Larval Midgut no informative data Larval Hindgut    74.2 Larval Malpighian Tubules    33.6 Larval Fat Body no informative data Larval Salivary Gland no informative data Larval Trachea    94.9 Larval Carcass    55.45 Adult Head    44.3 Adult Eye    56.975 Adult Brain    78.4 Adult Thoracic-Abdominal Ganglion    58.8 Adult Crop    65.4 Adult Midgut no informative data Adult Hindgut    56 Adult Malpighian Tubules    35.7 Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart    37.225 Adult VirginFemale Spermatheca    45.5 Adult InseminatedFemale Spermatheca    45.6 Adult Ovary    46.2 Adult Testis    9.7 Adult Male Accessory Gland no informative data Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    115.35 Larval Midgut no informative data Larval Hindgut    74.2 Larval Malpighian Tubules    33.6 Larval Fat Body no informative data Larval Salivary Gland no informative data Larval Trachea    94.9 Larval Carcass    55.45 Adult Head    44.3 Adult Eye    56.975 Adult Brain    78.4 Adult Thoracic-Abdominal Ganglion    58.8 Adult Crop    65.4 Adult Midgut no informative data Adult Hindgut    56 Adult Malpighian Tubules    35.7 Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart    37.225 Adult VirginFemale Spermatheca    45.5 Adult InseminatedFemale Spermatheca    45.6 Adult Ovary    46.2 Adult Testis    9.7 Adult Male Accessory Gland no informative data Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0035158 expression level Tissue   Expression Level Larval Central Nervous System    115.35 Larval Midgut no informative data Larval Hindgut    74.2 Larval Malpighian Tubules    33.6 Larval Fat Body no informative data Larval Salivary Gland no informative data Larval Trachea    94.9 Larval Carcass    55.45 Adult Head    44.3 Adult Eye    56.975 Adult Brain    78.4 Adult Thoracic-Abdominal Ganglion    58.8 Adult Crop    65.4 Adult Midgut no informative data Adult Hindgut    56 Adult Malpighian Tubules    35.7 Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart    37.225 Adult VirginFemale Spermatheca    45.5 Adult InseminatedFemale Spermatheca    45.6 Adult Ovary    46.2 Adult Testis    9.7 Adult Male Accessory Gland no informative data Adult Carcass no informative data Expression Level Scale  None   Low   Moderate  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    115.35 Larval Midgut no informative data Larval Hindgut    74.2 Larval Malpighian Tubules    33.6 Larval Fat Body no informative data Larval Salivary Gland no informative data Larval Trachea    94.9 Larval Carcass    55.45 Adult Head    44.3 Adult Eye    56.975 Adult Brain    78.4 Adult Thoracic-Abdominal Ganglion    58.8 Adult Crop    65.4 Adult Midgut no informative data Adult Hindgut    56 Adult Malpighian Tubules    35.7 Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart    37.225 Adult VirginFemale Spermatheca    45.5 Adult InseminatedFemale Spermatheca    45.6 Adult Ovary    46.2 Adult Testis    9.7 Adult Male Accessory Gland no informative data Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    115.35 Larval Midgut no informative data Larval Hindgut    74.2 Larval Malpighian Tubules    33.6 Larval Fat Body no informative data Larval Salivary Gland no informative data Larval Trachea    94.9 Larval Carcass    55.45 Adult Head    44.3 Adult Eye    56.975 Adult Brain    78.4 Adult Thoracic-Abdominal Ganglion    58.8 Adult Crop    65.4 Adult Midgut no informative data Adult Hindgut    56 Adult Malpighian Tubules    35.7 Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart    37.225 Adult VirginFemale Spermatheca    45.5 Adult InseminatedFemale Spermatheca    45.6 Adult Ovary    46.2 Adult Testis    9.7 Adult Male Accessory Gland no informative data Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    115.35 Larval Midgut no informative data Larval Hindgut    74.2 Larval Malpighian Tubules    33.6 Larval Fat Body no informative data Larval Salivary Gland no informative data Larval Trachea    94.9 Larval Carcass    55.45 Adult Head    44.3 Adult Eye    56.975 Adult Brain    78.4 Adult Thoracic-Abdominal Ganglion    58.8 Adult Crop    65.4 Adult Midgut no informative data Adult Hindgut    56 Adult Malpighian Tubules    35.7 Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart    37.225 Adult VirginFemale Spermatheca    45.5 Adult InseminatedFemale Spermatheca    45.6 Adult Ovary    46.2 Adult Testis    9.7 Adult Male Accessory Gland no informative data Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut no informative data Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body no informative data Larval Salivary Gland no informative data Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut no informative data Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland no informative data Adult Carcass no informative data FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    44.3   NA  Eye    56.975   NA  Brain    78.4   115.35  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    58.8   NA  Crop    65.4   no informative data  Midgut    no informative data   74.2  Hindgut    56   33.6  Malpighian Tubules    35.7   no informative data  Fat Body    no informative data   no informative data  Salivary Gland    no informative data   NA  Heart    37.225   94.9  Trachea    NA   NA  VirginFemale Spermatheca    45.5   NA  InseminatedFemale Spermatheca    45.6   NA  Ovary    46.2   NA  Testis    9.7   NA  Male Accessory Gland    no informative data   55.45  Carcass    no informative data modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_31
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0035158 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG13895-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable CG1389531 viable, with Scer\GAL4pnr-MD237 CG13895GD8159 Phenotype manifest in Allele
Classical Alleles ( 12 )
For All Classical Alleles Show
Allele of CG13895 Class Mutagen Stocks Known lesion CG1389531 1 Yes CG13895CB-6672-3 1 -- CG13895DG19407 1 -- CG13895KG05495 1 -- CG13895NP6605 1 -- CG13895190 P-element activity 0 Yes CG13895c05503 piggyBac transposase 0 -- CG13895d03881 P-element activity 0 -- CG13895d09290 P-element activity 0 -- CG13895EP14C P-element activity 0 -- CG13895EP3666 P-element activity 0 -- CG13895f07278 piggyBac transposase 0 --
Alleles Carried on Transgenic Constructs ( 2 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG13895 Class Mutagen Stocks Known lesion CG13895GD8159 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes CG13895Scer\UAS.cBa in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(3L)Exel6085 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD8159} NA P{UAS-CG13895.B} NA
Insertions
	Type of insertions Name Expression data insertion of mobile activating element P{EP}CG13895EP14C NA P{EP}CG13895EP3666 NA P{EP}EP3465 NA P{XP}CG13895d03881 NA P{XP}CG13895d09290 NA insertion of enhancer trap binary system P{GawB}CG13895NP6605 No miscellaneous insertions P{?SUPor-P}CG13895190 NA P{PTT-GB}CB04175 NA P{RS3}CG13895CB-6672-3 NA P{SUPor-P}CG13895KG05495 NA P{UASp-YFP.Rab2.Q65L}02 NA P{UASp-YFP.Rab11.Q70L}CG1389531 NA P{wHy}CG13895DG19407 NA PBac{PB}CG13895c05503 NA PBac{WH}CG13895f07278 NA
Gene Ontology: Function, Process & Cellular Component ( 3 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 3 terms )
Molecular Function
CV term Evidence References
DNA binding inferred from electronic annotation with InterPro:IPR006695, InterPro:IPR011526, InterPro:IPR012287 (FlyBase Curators et al., 2004-)
Biological Process
CV term Evidence References
regulation of transcription, DNA-dependent inferred from electronic annotation with InterPro:IPR012287 (FlyBase Curators et al., 2004-)
Cellular Component
CV term Evidence References
chromosome, centromeric region inferred from electronic annotation with InterPro:IPR006695 (FlyBase Curators et al., 2004-)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG13895 allele Gene References
External Data
Linkouts	DroID - A comprehensive database of gene and protein interactions. • FBgn0035158
Orthologs
Genome-wide drosophilid orthologs	Dana\GF24070 Dere\GG14642 Dgri\GH16035 Dmoj\GI12299 Dper\GL20834 Dpse\GA12609 Dsec\GM14257 Dsim\GD13514 Dvir\GJ13236 Dwil\GK16679 Dyak\GE21000
Curated drosophilid orthologs	Dpse\GA12609
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • XP_001946863.1 Acyrthosiphon pisum (pea aphid) ENSCAFP00000020065 Canis familiaris (dog) ENSECAP00000004936 Equus caballus (horse) 183752 Hypsipyla robusta (cedar shoot borer) ENSP00000308354 Homo sapiens (human) ENSMUSP00000059302 Mus musculus (house mouse) ENSPPYP00000003550 Pongo pygmaeus (orangutan) ENSPTRP00000006676 Pan troglodytes (chimpanzee) ENSRNOP00000035812 Rattus norvegicus (norway rat) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • FBgn0238283 FBgn0218681 FBgn0200462 FBgn0185225 FBgn0169183 FBgn0072655 FBgn0158429 FBgn0135056 FBgn0123506 FBgn0106898 FBgn0101064
Stocks & Reagents
Stocks Listed in FlyBase ( 7 )
Bloomington	9791 y1 w*; P{UASp-YFP.Rab11.Q70L}CG1389531 14008 y1 w67c23; P{SUPor-P}CG13895KG05495 ry506 21687 y1 w67c23; P{wHy}CG13895DG19407/TM3, Sb1 Ser1
Kyoto	124174 w1118; P{RS3}CG13895CB-6672-3 / TM6C, Sb1 105284 y* w*; P{GawB}CG13895NP6605 / TM6, P{UAS-lacZ.UW23-1}UW23-1
VDRC	v41511 w1118; P{GD8159}v41511 v41512 w1118; P{GD8159}v41512
Genomic Clones ( 2 )
	BACR04C03 BACR26C18 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 25 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	RE63174
Other clones	FI01820
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	RE26122 RE39666
Other clones	32084 273737 CK01.56C.H5 EK045624 EK142427 EK298847 RM02794 RM03094 RP001005088 RP001005853 RP001021553 RP001022677 RP001022768 RP001025337 RP001025778 RP001025826 RP001037619 RP001041617 RP001047648 RP001052182 RP001052292
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0035158 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 38087
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_138211 RefSeq (Proteins) • NP_612055 DDBJ / EMBL / GenBank • AAF47409 AAL49190 AQ073102 AY071568 BI375386 CZ470046 CZ473606 CZ473607 CZ476659 CZ476660 CZ490094 Entrez Gene - A searchable database of RefSeq genes. • 38087 UniProtKB/TrEMBL • Q8SYG6 Q9W0N4
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Pogo transposase / Cenp-B / PDC2, DNA-binding HTH domain (IPR006600) Centromere protein Cenp-B, DNA-binding domain 1 (IPR006695) Homeodomain-like (IPR009057) Helix-turn-helix, Psq-like (IPR011526) Homeodomain-related (IPR012287)
Linkouts
	DroID - A comprehensive database of gene and protein interactions. • FBgn0035158 DRSC - Results from RNAi screens. • FBgn0035158 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0035158 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG13895-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0035158 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 38087 InParanoid A subset of ortholog calls from InParanoid. • XP_001946863.1 Acyrthosiphon pisum (pea aphid) ENSCAFP00000020065 Canis familiaris (dog) ENSECAP00000004936 Equus caballus (horse) 183752 Hypsipyla robusta (cedar shoot borer) ENSP00000308354 Homo sapiens (human) ENSMUSP00000059302 Mus musculus (house mouse) ENSPPYP00000003550 Pongo pygmaeus (orangutan) ENSPTRP00000006676 Pan troglodytes (chimpanzee) ENSRNOP00000035812 Rattus norvegicus (norway rat) modMine - Data generated by the modENCODE project. • FBgn0035158 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • FBgn0238283 FBgn0218681 FBgn0200462 FBgn0185225 FBgn0169183 FBgn0072655 FBgn0158429 FBgn0135056 FBgn0123506 FBgn0106898 FBgn0101064
Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	CG13895 (Weber et al., 2008, Buszczak et al., 2007, Benchabane et al., 2011, Arancio et al., 2010, Zhang et al., 2007, Schneiderman et al., 2010)
Name Synonym
Secondary FlyBase IDs
References ( 21 )
Generate a list of	All references relating to this gene ( 21 )
List References by type	Research paper  ( 6 ) Supplementary material  ( 4 ) Personal communication to FlyBase  ( 4 ) FlyBase analysis  ( 2 ) Computer file  ( 3 ) Automatic genome annotation  ( 1 )
Recent research papers ( 3 )
	Arancio et al., 2010, Genetics 185(1): 129--140 The nucleosome remodeling factor ISWI functionally interacts with an evolutionarily conserved network of cellular factors. [FBrf0213976] Blanco et al., 2010, BMC Dev. Biol. 10: 94 Gene expression following induction of regeneration in Drosophila wing imaginal discs. Expression profile of regenerating wing discs. [FBrf0211812] Schneiderman et al., 2010, PLoS Genet. 6(9): e1001095 Perturbation Analysis of Heterochromatin-Mediated Gene Silencing and Somatic Inheritance. [FBrf0211786] Show all research papers ...