A Database of Drosophila Genes & Genomes

FB2012_01, released January 20th, 2012
 

Gene Dmel\CG13900

General Information
SymbolDmel\CG13900SpeciesD. melanogaster
NameAnnotation symbolCG13900
Feature typeprotein_coding_geneFlyBase IDFBgn0035162
Gene Model StatusCurrent Stock availability 4 publicly available
Genomic Location
Chromosome (arm)3LRecombination map
Cytogenetic map61D2-61D2Sequence location3L:826,710..833,402 [-]

Genomic Maps

GBrowse View Help
modENCODE GBrowse
detailed view
hide Summary Information
Automatically generated summary

See sections below for more information
This gene is referred to in FlyBase by the symbol Dmel\CG13900 (FBgn0035162). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: damaged DNA binding. There is experimental evidence that it is involved in the biological process: mitotic spindle organization; neurogenesis. 4 alleles are reported. The phenotype of these alleles is annotated with: mesothoracic tergum. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Cleavage/polyadenylation specificity factor, A subunit, C-terminal; WD40/YVTN repeat-like-containing domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression. Peak expression observed at stages throughout embryogenesis, during early larval stages. Summary of FlyAtlas Anatomical Expression Data: Many larval and adult organs/tissues expressed at moderate levels. Expression at high levels in the following post-embryonic organs or tissues: larval central nervous system, larval salivary gland, larval trachea, adult ovary. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, adult Malpighian tubules, adult heart, larval/adult fat body, adult salivary gland, adult spermathecae, adult male accessory gland, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1633394_a_at completely aligns to an exonic region common to each of the 2 FlyBase-annotated transcript isoforms of CG13900. Gene sequence location is 3L:826710..833402.

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Description
What does this section display?
This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms).
What does this section not display?
This section does not currently display links that were removed or gene model changes.
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FB2012_01
Sequence features
FB2011_10
References
All updates Click here to see a list of all updates to this record from FB2010_08 and on.
hide Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map
Evidence for location
61D2-61D2  
Limits computationally determined from genome sequence between P{PZ}l(3)0596705967 and P{PZ}l(3)0264002640  
Experimentally Determined Cytological Location
Cytogenetic map
Notes
References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
hide Gene Model & Products
Please see the GBrowse view of Dmel\CG13900 for information on other features
To submit a correction to a gene model please use the Contact FlyBase form
detailed view FBtr0114338 FBtr0114339 FBtr0114340 FBtr0114341 FBtr0072598 FBtr0114342 FBtr0114343 FBtr0113600 FBtr0113601 FBtr0113602 FBtr0072597 FBtr0301252 FBpp0072495 FBpp0072494 FBpp0290467 FBti0050088 FBti0105728 FBti0005413 FBti0125460_1 FBti0125460_2 FBti0125461 FBti0035266
Comments on Gene Model
Atypical structure of 3' UTR supported by multiple ESTs.
DGC clone GM01240 appears problematic: incomplete CDS
hide Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Associated CDS (aa)
FBtr0072597
  4249
  1227
FBtr0072598
  2487
  688
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
hide Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kDa)
Length (aa)
Theoretical pI
RefSeq ID
GenBank protein
FBpp0072494  
136.6  
1227  
5.13  
FBpp0072495  
77.0  
688  
5.53  
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences
InterPro domains - A database of protein families, domains, and functional sites
hide Sequences Consistent with the Gene Model
DDBJ /
EMBL /
GenBank
DNA sequence
Protein sequence
Name
 
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL
hide Mapped Features
Mapped Features have been reorganized, please see this article for details.
Additional mapped features and mutations can be found on GBrowse or related reports.
Type
Symbol & Location
Additional Notes
References
hide External Data
Linkouts
Crossreferences
hide Expression Data
hideTranscript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
hidePolypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
hide High-Throughput Expression Data
or
Untitled Document detailed view snoRNA:Me28S-C788b-RA snoRNA:Me28S-C788a-RA snoRNA:Me28S-G3113b-RA snoRNA:Me28S-G3113a-RA CG13900-RB snoRNA:Me5.8S-G74-RA snoRNA:Me28S-A771-RA snoRNA:Psi18S-110-RA snoRNA:Psi28S-3308-RA snoRNA:Psi18S-1086-RA CG13900-RA CG42553-RA
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.

modENCODE Temporal Expression Data for FBgn0035162


   Styles
Linear
Logarithmic
Heatmap
   Scales
max expr for FBgn0035162
Very low expression bin max
Moderate expression bin max
High expression bin max
Extremely high expression bin max

Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression. Peak expression observed at stages throughout embryogenesis, during early larval stages.
[download data (TSV)]

Guide to modENCODE expression level colors
 
No expression (0 - 0)
 
Extremely low expression (1 - 10)
 
Very low expression (11 - 100)
 
Low expression (101 - 400)
 
Moderate expression (401 - 1400)
 
Moderately high expression (1401 - 4000)
 
High expression (4001 - 10000)
 
Very high expression (10001 - 100000)
 
Extremely high expression (100001 - 2000000)

Linear, scaled to maximum FBgn0035162 expression level
Developmental Stage   Expression Level
embryo 00-02hr
 
 8583
embryo 02-04hr
 
 18213
embryo 04-06hr
 
 23004
embryo 06-08hr
 
 17103
embryo 08-10hr
 
 16605
embryo 10-12hr
 
 13997
embryo 12-14hr
 
 12081
embryo 14-16hr
 
 10404
embryo 16-18hr
 
 6621
embryo 18-20hr
 
 4418
embryo 20-22hr
 
 10071
embryo 22-24hr
 
 8763
larva L1
 
 14307
larva L2
 
 7497
larva L3 12hr old
 
 5404
larva L3 puffstage 1-2
 
 2684
larva L3 puffstage 3-6
 
 3712
larva L3 puffstage 7-9
 
 4468
white prepupae new
 
 4650
white prepupae 12hr
 
 4330
white prepupae 24hr
 
 5110
pupae 2d postWPP
 
 3176
pupae 3d postWPP
 
 1567
pupae 4d postWPP
 
 2154
adult male 01day
 
 1420
adult male 05day
 
 1454
adult male 30day
 
 1835
adult female 01day
 
 7846
adult female 05day
 
 8559
adult female 30day
 
 7928
Expression Level Scale
 None 
 Extremely low 
 Very low 
 Low 
 Moderate 
 Moderately high 
 High 
 Very high 
Linear, scaled to Very low expression
Developmental Stage   Expression Level
embryo 00-02hr
 (8583)
embryo 02-04hr
 (18213)
embryo 04-06hr
 (23004)
embryo 06-08hr
 (17103)
embryo 08-10hr
 (16605)
embryo 10-12hr
 (13997)
embryo 12-14hr
 (12081)
embryo 14-16hr
 (10404)
embryo 16-18hr
 (6621)
embryo 18-20hr
 (4418)
embryo 20-22hr
 (10071)
embryo 22-24hr
 (8763)
larva L1
 (14307)
larva L2
 (7497)
larva L3 12hr old
 (5404)
larva L3 puffstage 1-2
 (2684)
larva L3 puffstage 3-6
 (3712)
larva L3 puffstage 7-9
 (4468)
white prepupae new
 (4650)
white prepupae 12hr
 (4330)
white prepupae 24hr
 (5110)
pupae 2d postWPP
 (3176)
pupae 3d postWPP
 (1567)
pupae 4d postWPP
 (2154)
adult male 01day
 (1420)
adult male 05day
 (1454)
adult male 30day
 (1835)
adult female 01day
 (7846)
adult female 05day
 (8559)
adult female 30day
 (7928)
Expression Level Scale
 None 
 Extremely low 
 Very low 
 Low 
Linear, scaled to Moderate expression
Developmental Stage   Expression Level
embryo 00-02hr
 (8583)
embryo 02-04hr
 (18213)
embryo 04-06hr
 (23004)
embryo 06-08hr
 (17103)
embryo 08-10hr
 (16605)
embryo 10-12hr
 (13997)
embryo 12-14hr
 (12081)
embryo 14-16hr
 (10404)
embryo 16-18hr
 (6621)
embryo 18-20hr
 (4418)
embryo 20-22hr
 (10071)
embryo 22-24hr
 (8763)
larva L1
 (14307)
larva L2
 (7497)
larva L3 12hr old
 (5404)
larva L3 puffstage 1-2
 (2684)
larva L3 puffstage 3-6
 (3712)
larva L3 puffstage 7-9
 (4468)
white prepupae new
 (4650)
white prepupae 12hr
 (4330)
white prepupae 24hr
 (5110)
pupae 2d postWPP
 (3176)
pupae 3d postWPP
 (1567)
pupae 4d postWPP
 (2154)
adult male 01day
 1420
adult male 05day
 1454
adult male 30day
 (1835)
adult female 01day
 (7846)
adult female 05day
 (8559)
adult female 30day
 (7928)
Expression Level Scale
 None 
 Extremely low 
 Very low 
 Low 
 Moderate 
 Moderately high 
Linear, scaled to High expression
Developmental Stage   Expression Level
embryo 00-02hr
 
 8583
embryo 02-04hr
 (18213)
embryo 04-06hr
 (23004)
embryo 06-08hr
 (17103)
embryo 08-10hr
 (16605)
embryo 10-12hr
 (13997)
embryo 12-14hr
 (12081)
embryo 14-16hr
 10404
embryo 16-18hr
 
 6621
embryo 18-20hr
 
 4418
embryo 20-22hr
 10071
embryo 22-24hr
 
 8763
larva L1
 (14307)
larva L2
 
 7497
larva L3 12hr old
 
 5404
larva L3 puffstage 1-2
 
 2684
larva L3 puffstage 3-6
 
 3712
larva L3 puffstage 7-9
 
 4468
white prepupae new
 
 4650
white prepupae 12hr
 
 4330
white prepupae 24hr
 
 5110
pupae 2d postWPP
 
 3176
pupae 3d postWPP
 
 1567
pupae 4d postWPP
 
 2154
adult male 01day
 
 1420
adult male 05day
 
 1454
adult male 30day
 
 1835
adult female 01day
 
 7846
adult female 05day
 
 8559
adult female 30day
 
 7928
Expression Level Scale
 None 
 Extremely low 
 Very low 
 Low 
 Moderate 
 Moderately high 
 High 
 Very high 
Linear, scaled to Extremely high expression
Developmental Stage   Expression Level
embryo 00-02hr
 
 8583
embryo 02-04hr
 
 18213
embryo 04-06hr
 
 23004
embryo 06-08hr
 
 17103
embryo 08-10hr
 
 16605
embryo 10-12hr
 
 13997
embryo 12-14hr
 
 12081
embryo 14-16hr
 
 10404
embryo 16-18hr
 
 6621
embryo 18-20hr
 
 4418
embryo 20-22hr
 
 10071
embryo 22-24hr
 
 8763
larva L1
 
 14307
larva L2
 
 7497
larva L3 12hr old
 
 5404
larva L3 puffstage 1-2
 
 2684
larva L3 puffstage 3-6
 
 3712
larva L3 puffstage 7-9
 
 4468
white prepupae new
 
 4650
white prepupae 12hr
 
 4330
white prepupae 24hr
 
 5110
pupae 2d postWPP
 
 3176
pupae 3d postWPP
 
 1567
pupae 4d postWPP
 
 2154
adult male 01day
 
 1420
adult male 05day
 
 1454
adult male 30day
 
 1835
adult female 01day
 
 7846
adult female 05day
 
 8559
adult female 30day
 
 7928
Expression Level Scale
 None 
 Extremely low 
 Very low 
 Low 
 Moderate 
 Moderately high 
 High 
 Very high 
 Extremely high 
log, scaled to maximum FBgn0035162 expression level
Developmental Stage   Expression Level
embryo 00-02hr
 
 8583
embryo 02-04hr
 
 18213
embryo 04-06hr
 
 23004
embryo 06-08hr
 
 17103
embryo 08-10hr
 
 16605
embryo 10-12hr
 
 13997
embryo 12-14hr
 
 12081
embryo 14-16hr
 
 10404
embryo 16-18hr
 
 6621
embryo 18-20hr
 
 4418
embryo 20-22hr
 
 10071
embryo 22-24hr
 
 8763
larva L1
 
 14307
larva L2
 
 7497
larva L3 12hr old
 
 5404
larva L3 puffstage 1-2
 
 2684
larva L3 puffstage 3-6
 
 3712
larva L3 puffstage 7-9
 
 4468
white prepupae new
 
 4650
white prepupae 12hr
 
 4330
white prepupae 24hr
 
 5110
pupae 2d postWPP
 
 3176
pupae 3d postWPP
 
 1567
pupae 4d postWPP
 
 2154
adult male 01day
 
 1420
adult male 05day
 
 1454
adult male 30day
 
 1835
adult female 01day
 
 7846
adult female 05day
 
 8559
adult female 30day
 
 7928
Expression Level Scale
 None 
 Extremely low 
 Very low 
 Low 
 Moderate 
 Moderately high 
 High 
 Very high 
log, scaled to Very low expression
Developmental Stage   Expression Level
embryo 00-02hr
 (8583)
embryo 02-04hr
 (18213)
embryo 04-06hr
 (23004)
embryo 06-08hr
 (17103)
embryo 08-10hr
 (16605)
embryo 10-12hr
 (13997)
embryo 12-14hr
 (12081)
embryo 14-16hr
 (10404)
embryo 16-18hr
 (6621)
embryo 18-20hr
 (4418)
embryo 20-22hr
 (10071)
embryo 22-24hr
 (8763)
larva L1
 (14307)
larva L2
 (7497)
larva L3 12hr old
 (5404)
larva L3 puffstage 1-2
 (2684)
larva L3 puffstage 3-6
 (3712)
larva L3 puffstage 7-9
 (4468)
white prepupae new
 (4650)
white prepupae 12hr
 (4330)
white prepupae 24hr
 (5110)
pupae 2d postWPP
 (3176)
pupae 3d postWPP
 (1567)
pupae 4d postWPP
 (2154)
adult male 01day
 (1420)
adult male 05day
 (1454)
adult male 30day
 (1835)
adult female 01day
 (7846)
adult female 05day
 (8559)
adult female 30day
 (7928)
Expression Level Scale
 None 
 Extremely low 
 Very low 
 Low 
log, scaled to Moderate expression
Developmental Stage   Expression Level
embryo 00-02hr
 (8583)
embryo 02-04hr
 (18213)
embryo 04-06hr
 (23004)
embryo 06-08hr
 (17103)
embryo 08-10hr
 (16605)
embryo 10-12hr
 (13997)
embryo 12-14hr
 (12081)
embryo 14-16hr
 (10404)
embryo 16-18hr
 (6621)
embryo 18-20hr
 (4418)
embryo 20-22hr
 (10071)
embryo 22-24hr
 (8763)
larva L1
 (14307)
larva L2
 (7497)
larva L3 12hr old
 (5404)
larva L3 puffstage 1-2
 (2684)
larva L3 puffstage 3-6
 (3712)
larva L3 puffstage 7-9
 (4468)
white prepupae new
 (4650)
white prepupae 12hr
 (4330)
white prepupae 24hr
 (5110)
pupae 2d postWPP
 (3176)
pupae 3d postWPP
 1567
pupae 4d postWPP
 2154
adult male 01day
 1420
adult male 05day
 1454
adult male 30day
 1835
adult female 01day
 (7846)
adult female 05day
 (8559)
adult female 30day
 (7928)
Expression Level Scale
 None 
 Extremely low 
 Very low 
 Low 
 Moderate 
 Moderately high 
log, scaled to High expression
Developmental Stage   Expression Level
embryo 00-02hr
 
 8583
embryo 02-04hr
 18213
embryo 04-06hr
 (23004)
embryo 06-08hr
 17103
embryo 08-10hr
 16605
embryo 10-12hr
 13997
embryo 12-14hr
 12081
embryo 14-16hr
 10404
embryo 16-18hr
 
 6621
embryo 18-20hr
 
 4418
embryo 20-22hr
 10071
embryo 22-24hr
 
 8763
larva L1
 14307
larva L2
 
 7497
larva L3 12hr old
 
 5404
larva L3 puffstage 1-2
 
 2684
larva L3 puffstage 3-6
 
 3712
larva L3 puffstage 7-9
 
 4468
white prepupae new
 
 4650
white prepupae 12hr
 
 4330
white prepupae 24hr
 
 5110
pupae 2d postWPP
 
 3176
pupae 3d postWPP
 
 1567
pupae 4d postWPP
 
 2154
adult male 01day
 
 1420
adult male 05day
 
 1454
adult male 30day
 
 1835
adult female 01day
 
 7846
adult female 05day
 
 8559
adult female 30day
 
 7928
Expression Level Scale
 None 
 Extremely low 
 Very low 
 Low 
 Moderate 
 Moderately high 
 High 
 Very high 
log, scaled to Extremely high expression
Developmental Stage   Expression Level
embryo 00-02hr
 
 8583
embryo 02-04hr
 
 18213
embryo 04-06hr
 
 23004
embryo 06-08hr
 
 17103
embryo 08-10hr
 
 16605
embryo 10-12hr
 
 13997
embryo 12-14hr
 
 12081
embryo 14-16hr
 
 10404
embryo 16-18hr
 
 6621
embryo 18-20hr
 
 4418
embryo 20-22hr
 
 10071
embryo 22-24hr
 
 8763
larva L1
 
 14307
larva L2
 
 7497
larva L3 12hr old
 
 5404
larva L3 puffstage 1-2
 
 2684
larva L3 puffstage 3-6
 
 3712
larva L3 puffstage 7-9
 
 4468
white prepupae new
 
 4650
white prepupae 12hr
 
 4330
white prepupae 24hr
 
 5110
pupae 2d postWPP
 
 3176
pupae 3d postWPP
 
 1567
pupae 4d postWPP
 
 2154
adult male 01day
 
 1420
adult male 05day
 
 1454
adult male 30day
 
 1835
adult female 01day
 
 7846
adult female 05day
 
 8559
adult female 30day
 
 7928
Expression Level Scale
 None 
 Extremely low 
 Very low 
 Low 
 Moderate 
 Moderately high 
 High 
 Very high 
 Extremely high 
Heatmap
Developmental Stage   Expression Level
embryo 00-02hr
 
 
embryo 02-04hr
 
 
embryo 04-06hr
 
 
embryo 06-08hr
 
 
embryo 08-10hr
 
 
embryo 10-12hr
 
 
embryo 12-14hr
 
 
embryo 14-16hr
 
 
embryo 16-18hr
 
 
embryo 18-20hr
 
 
embryo 20-22hr
 
 
embryo 22-24hr
 
 
larva L1
 
 
larva L2
 
 
larva L3 12hr old
 
 
larva L3 puffstage 1-2
 
 
larva L3 puffstage 3-6
 
 
larva L3 puffstage 7-9
 
 
white prepupae new
 
 
white prepupae 12hr
 
 
white prepupae 24hr
 
 
pupae 2d postWPP
 
 
pupae 3d postWPP
 
 
pupae 4d postWPP
 
 
adult male 01day
 
 
adult male 05day
 
 
adult male 30day
 
 
adult female 01day
 
 
adult female 05day
 
 
adult female 30day
 
 

FlyAtlas Anatomical Expression Data for FBgn0035162


   Styles
Linear
Logarithmic
Heatmap
Back-to-back
   Scales
max expr for FBgn0035162
Moderate expression bin max
High level expression bin max
Very high expression bin max

Summary of FlyAtlas Anatomical Expression Data: Many larval and adult organs/tissues expressed at moderate levels. Expression at high levels in the following post-embryonic organs or tissues: larval central nervous system, larval salivary gland, larval trachea, adult ovary. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, adult Malpighian tubules, adult heart, larval/adult fat body, adult salivary gland, adult spermathecae, adult male accessory gland, larval/adult carcass.
[download data (TSV)]

Guide to FlyAtlas expression level colors
 
No expression (0 - 9.999)
 
Low expression (10 - 99.999)
 
Moderate expression (100 - 499.999)
 
High level expression (500 - 999.999)
 
Very high expression (1000 - 25000)

Linear, scaled to maximum FBgn0035162 expression level
Tissue   Expression Level
Larval Central Nervous System
 
 719.425
Larval Midgut
 
 203.9
Larval Hindgut
 
 352.1
Larval Malpighian Tubules
 
 96.2
Larval Fat Body
 
 101.3
Larval Salivary Gland
 
 559.9
Larval Trachea
 
 540.725
Larval Carcass
 
 426.75
Adult Head
 
 137.7
Adult Eye
 
 83.875
Adult Brain
 
 157.7
Adult Thoracic-Abdominal Ganglion
 
 119.4
Adult Crop
 
 199.1
Adult Midgut
 
 204.2
Adult Hindgut
 
 143.4
Adult Malpighian Tubules
 
 219.7
Adult Fat Body
 
 188.6
Adult Salivary Gland
 
 272
Adult Heart
 
 118.9
Adult VirginFemale Spermatheca
 
 225.4
Adult InseminatedFemale Spermatheca
 
 353.2
Adult Ovary
 
 601.4
Adult Testis
 
 57.5
Adult Male Accessory Gland
 
 272.3
Adult Carcass
 
 133.7
Expression Level Scale
 None 
 Low 
 Moderate 
 High 
Linear, scaled to Moderate expression
Tissue   Expression Level
Larval Central Nervous System
 (719.425)
Larval Midgut
 
 203.9
Larval Hindgut
 
 352.1
Larval Malpighian Tubules
 
 96.2
Larval Fat Body
 
 101.3
Larval Salivary Gland
 (559.9)
Larval Trachea
 (540.725)
Larval Carcass
 
 426.75
Adult Head
 
 137.7
Adult Eye
 
 83.875
Adult Brain
 
 157.7
Adult Thoracic-Abdominal Ganglion
 
 119.4
Adult Crop
 
 199.1
Adult Midgut
 
 204.2
Adult Hindgut
 
 143.4
Adult Malpighian Tubules
 
 219.7
Adult Fat Body
 
 188.6
Adult Salivary Gland
 
 272
Adult Heart
 
 118.9
Adult VirginFemale Spermatheca
 
 225.4
Adult InseminatedFemale Spermatheca
 
 353.2
Adult Ovary
 (601.4)
Adult Testis
 
 57.5
Adult Male Accessory Gland
 
 272.3
Adult Carcass
 
 133.7
Expression Level Scale
 None 
 Low 
 Moderate 
 High 
Linear, scaled to High level expression
Tissue   Expression Level
Larval Central Nervous System
 
 719.425
Larval Midgut
 
 203.9
Larval Hindgut
 
 352.1
Larval Malpighian Tubules
 
 96.2
Larval Fat Body
 
 101.3
Larval Salivary Gland
 
 559.9
Larval Trachea
 
 540.725
Larval Carcass
 
 426.75
Adult Head
 
 137.7
Adult Eye
 
 83.875
Adult Brain
 
 157.7
Adult Thoracic-Abdominal Ganglion
 
 119.4
Adult Crop
 
 199.1
Adult Midgut
 
 204.2
Adult Hindgut
 
 143.4
Adult Malpighian Tubules
 
 219.7
Adult Fat Body
 
 188.6
Adult Salivary Gland
 
 272
Adult Heart
 
 118.9
Adult VirginFemale Spermatheca
 
 225.4
Adult InseminatedFemale Spermatheca
 
 353.2
Adult Ovary
 
 601.4
Adult Testis
 
 57.5
Adult Male Accessory Gland
 
 272.3
Adult Carcass
 
 133.7
Expression Level Scale
 None 
 Low 
 Moderate 
 High 
 Very high 
Linear, scaled to Very high expression
Tissue   Expression Level
Larval Central Nervous System
 
 719.425
Larval Midgut
 
 203.9
Larval Hindgut
 
 352.1
Larval Malpighian Tubules
 
 96.2
Larval Fat Body
 
 101.3
Larval Salivary Gland
 
 559.9
Larval Trachea
 
 540.725
Larval Carcass
 
 426.75
Adult Head
 
 137.7
Adult Eye
 
 83.875
Adult Brain
 
 157.7
Adult Thoracic-Abdominal Ganglion
 
 119.4
Adult Crop
 
 199.1
Adult Midgut
 
 204.2
Adult Hindgut
 
 143.4
Adult Malpighian Tubules
 
 219.7
Adult Fat Body
 
 188.6
Adult Salivary Gland
 
 272
Adult Heart
 
 118.9
Adult VirginFemale Spermatheca
 
 225.4
Adult InseminatedFemale Spermatheca
 
 353.2
Adult Ovary
 
 601.4
Adult Testis
 
 57.5
Adult Male Accessory Gland
 
 272.3
Adult Carcass
 
 133.7
Expression Level Scale
 None 
 Low 
 Moderate 
 High 
 Very high 
log, scaled to maximum FBgn0035162 expression level
Tissue   Expression Level
Larval Central Nervous System
 
 719.425
Larval Midgut
 
 203.9
Larval Hindgut
 
 352.1
Larval Malpighian Tubules
 
 96.2
Larval Fat Body
 
 101.3
Larval Salivary Gland
 
 559.9
Larval Trachea
 
 540.725
Larval Carcass
 
 426.75
Adult Head
 
 137.7
Adult Eye
 
 83.875
Adult Brain
 
 157.7
Adult Thoracic-Abdominal Ganglion
 
 119.4
Adult Crop
 
 199.1
Adult Midgut
 
 204.2
Adult Hindgut
 
 143.4
Adult Malpighian Tubules
 
 219.7
Adult Fat Body
 
 188.6
Adult Salivary Gland
 
 272
Adult Heart
 
 118.9
Adult VirginFemale Spermatheca
 
 225.4
Adult InseminatedFemale Spermatheca
 
 353.2
Adult Ovary
 
 601.4
Adult Testis
 
 57.5
Adult Male Accessory Gland
 
 272.3
Adult Carcass
 
 133.7
Expression Level Scale
 None 
 Low 
 Moderate 
 High 
 Very high 
log, scaled to Moderate expression
Tissue   Expression Level
Larval Central Nervous System
 719.425
Larval Midgut
 
 203.9
Larval Hindgut
 
 352.1
Larval Malpighian Tubules
 
 96.2
Larval Fat Body
 
 101.3
Larval Salivary Gland
 559.9
Larval Trachea
 540.725
Larval Carcass
 
 426.75
Adult Head
 
 137.7
Adult Eye
 
 83.875
Adult Brain
 
 157.7
Adult Thoracic-Abdominal Ganglion
 
 119.4
Adult Crop
 
 199.1
Adult Midgut
 
 204.2
Adult Hindgut
 
 143.4
Adult Malpighian Tubules
 
 219.7
Adult Fat Body
 
 188.6
Adult Salivary Gland
 
 272
Adult Heart
 
 118.9
Adult VirginFemale Spermatheca
 
 225.4
Adult InseminatedFemale Spermatheca
 
 353.2
Adult Ovary
 601.4
Adult Testis
 
 57.5
Adult Male Accessory Gland
 
 272.3
Adult Carcass
 
 133.7
Expression Level Scale
 None 
 Low 
 Moderate 
 High 
log, scaled to High level expression
Tissue   Expression Level
Larval Central Nervous System
 
 719.425
Larval Midgut
 
 203.9
Larval Hindgut
 
 352.1
Larval Malpighian Tubules
 
 96.2
Larval Fat Body
 
 101.3
Larval Salivary Gland
 
 559.9
Larval Trachea
 
 540.725
Larval Carcass
 
 426.75
Adult Head
 
 137.7
Adult Eye
 
 83.875
Adult Brain
 
 157.7
Adult Thoracic-Abdominal Ganglion
 
 119.4
Adult Crop
 
 199.1
Adult Midgut
 
 204.2
Adult Hindgut
 
 143.4
Adult Malpighian Tubules
 
 219.7
Adult Fat Body
 
 188.6
Adult Salivary Gland
 
 272
Adult Heart
 
 118.9
Adult VirginFemale Spermatheca
 
 225.4
Adult InseminatedFemale Spermatheca
 
 353.2
Adult Ovary
 
 601.4
Adult Testis
 
 57.5
Adult Male Accessory Gland
 
 272.3
Adult Carcass
 
 133.7
Expression Level Scale
 None 
 Low 
 Moderate 
 High 
 Very high 
log, scaled to Very high expression
Tissue   Expression Level
Larval Central Nervous System
 
 719.425
Larval Midgut
 
 203.9
Larval Hindgut
 
 352.1
Larval Malpighian Tubules
 
 96.2
Larval Fat Body
 
 101.3
Larval Salivary Gland
 
 559.9
Larval Trachea
 
 540.725
Larval Carcass
 
 426.75
Adult Head
 
 137.7
Adult Eye
 
 83.875
Adult Brain
 
 157.7
Adult Thoracic-Abdominal Ganglion
 
 119.4
Adult Crop
 
 199.1
Adult Midgut
 
 204.2
Adult Hindgut
 
 143.4
Adult Malpighian Tubules
 
 219.7
Adult Fat Body
 
 188.6
Adult Salivary Gland
 
 272
Adult Heart
 
 118.9
Adult VirginFemale Spermatheca
 
 225.4
Adult InseminatedFemale Spermatheca
 
 353.2
Adult Ovary
 
 601.4
Adult Testis
 
 57.5
Adult Male Accessory Gland
 
 272.3
Adult Carcass
 
 133.7
Expression Level Scale
 None 
 Low 
 Moderate 
 High 
 Very high 
Heatmap
Tissue   Expression Level
Larval Central Nervous System
 
 
Larval Midgut
 
 
Larval Hindgut
 
 
Larval Malpighian Tubules
 
 
Larval Fat Body
 
 
Larval Salivary Gland
 
 
Larval Trachea
 
 
Larval Carcass
 
 
Adult Head
 
 
Adult Eye
 
 
Adult Brain
 
 
Adult Thoracic-Abdominal Ganglion
 
 
Adult Crop
 
 
Adult Midgut
 
 
Adult Hindgut
 
 
Adult Malpighian Tubules
 
 
Adult Fat Body
 
 
Adult Salivary Gland
 
 
Adult Heart
 
 
Adult VirginFemale Spermatheca
 
 
Adult InseminatedFemale Spermatheca
 
 
Adult Ovary
 
 
Adult Testis
 
 
Adult Male Accessory Gland
 
 
Adult Carcass
 
 

FlyAtlas Organ/Tissue Expression, larval vs. adult
Larval Expression Level Tissue Adult Expression Level
 
NA 
Head
 
 137.7
 
NA 
Eye
 
 83.875
 
NA 
Brain
 
 157.7
 
719.425 
Central Nervous System
 
 NA
 
NA 
Thoracic-Abdominal Ganglion
 
 119.4
 
NA 
Crop
 
 199.1
 
203.9 
Midgut
 
 204.2
 
352.1 
Hindgut
 
 143.4
 
96.2 
Malpighian Tubules
 
 219.7
 
101.3 
Fat Body
 
 188.6
 
559.9 
Salivary Gland
 
 272
 
NA 
Heart
 
 118.9
 
540.725 
Trachea
 
 NA
 
NA 
VirginFemale Spermatheca
 
 225.4
 
NA 
InseminatedFemale Spermatheca
 
 353.2
 
NA 
Ovary
 
 601.4
 
NA 
Testis
 
 57.5
 
NA 
Male Accessory Gland
 
 272.3
 
426.75 
Carcass
 
 133.7

modENCODE Temporal Expression Data (Graveley et al., 2011)
FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
hide Expression Clusters
A cluster of genes with similar mRNA expression dynamics across development.
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Linkouts
FLIGHT - Cell culture data for RNAi and other high-throughput technologies
FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
FlyExpress - Embryonic expression images (BDGP data)
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hide Summary of Allele Phenotypes
Lethality
Allele
Other Phenotypes
Allele
Phenotype manifest in
Allele
hide Classical Alleles ( 1 )
For All Classical Alleles Show

Allele of CG13900ClassMutagenStocksKnown lesion
CG13900f016091 --
hide Alleles Carried on Transgenic Constructs ( 3 )
For All Alleles Carried on Transgenic Constructs Show

Allele of CG13900ClassMutagenStocksKnown lesion
CG13900GD49191 Yes
CG13900HMS006141 Yes
CG13900KK1075131 Yes
hide Aneuploid Aberrations
Disrupted in
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Transgenic Constructs
Type of construct
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Type of insertions
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miscellaneous insertions
hide Gene Ontology: Function, Process & Cellular Component ( 8 unique terms )
hide Terms Based on Experimental Evidence ( 4 terms )
Molecular Function ( 0 terms)
Biological Process
CV term
References
inferred from mutant phenotype
inferred from mutant phenotype
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CV term
References
hide Terms Based on Predictions or Assertions ( 4 terms )
Molecular Function
CV term
References
inferred from sequence or structural similarity with EMBL:AF159853
Biological Process
CV term
References
inferred by curator from GO:0071011|GO:0071013
inferred from sequence or structural similarity with Saccharomyces RSE1 AND inferred from sequence or structural similarity with NCBI:CAB56791
Cellular Component
CV term
References
inferred from sequence or structural similarity with Saccharomyces RSE1 AND inferred from sequence or structural similarity with NCBI:CAB56791
inferred from sequence or structural similarity with Saccharomyces RSE1 AND inferred from sequence or structural similarity with NCBI:CAB56791
hide Sequence Ontology: Class of Gene
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Protein-protein
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Interacts with
Please look at the allele data for full details of the genetic interactions
CG13900 allele
Gene
References
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Linkouts
BioGRID - A database of protein and genetic interactions
DPiM - DPiM, Drosophila Protein interaction Map
DroID - A comprehensive database of gene and protein interactions.
InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets.
hide Orthologs
Genome-wide drosophilid orthologs
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InParanoid A subset of ortholog calls from InParanoid.
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hide Stocks Listed in FlyBase ( 4 )
Bloomington
Harvard
VDRC
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Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
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Please Note
This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones
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Linkouts
DRSC - Results from RNAi screens.
GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents
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Source for database identity of
Source for database merge of
Additional comments
The "l(3)0083500835" allele fails to complement alleles of the "l(3)61Db-S" and "l(3)61Dc" loci to varying extents. This suggests that the "l(3)61Db-S" and "l(3)61Dc" loci may be physically close to each other so that the single P-element insertion that causes "l(3)0083500835" (P{PZ}l(3)0083500835) may impair the function of both genes. From the position of the P{PZ}l(3)0083500835 insertion, it is likely that "l(3)61Db-S" and "l(3)61Dc" correspond to "CG13900" and "CG13886", although a one-to-one assignment cannot be established.
hide Other Comments
Nonsense-mediated mRNA decay (NMD) down-regulates a distinct splice isoform(s) of this gene.
RNAi screen using dsRNA made from templates generated with primers directed against this gene results in a long metaphase spindle with misaligned chromosomes when assayed in S2 cells. This phenotype can be observed when the screen is performed with or without Cdc27 dsRNA.
Area matching Drosophila EST AA567184.
hide External Crossreferences & Linkouts
Sequence Crossreferences
RefSeq (Transcripts)
RefSeq (Proteins)
Entrez Gene - A searchable database of RefSeq genes.
Other Crossreferences
InterPro domains - A database of protein families, domains, and functional sites
Linkouts
BioGRID - A database of protein and genetic interactions
DPiM - DPiM, Drosophila Protein interaction Map
DroID - A comprehensive database of gene and protein interactions.
DRSC - Results from RNAi screens.
FLIGHT - Cell culture data for RNAi and other high-throughput technologies
FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans
GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents
InParanoid A subset of ortholog calls from InParanoid.
InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets.
modMine - Data generated by the modENCODE project.
OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs.
hide Synonyms & Secondary IDs ( 4 )
Reported As
Symbol Synonym
Name Synonym
putative damaged DNA-binding activity
splicing factor 3b subunit 3
Secondary FlyBase IDs
hide References ( 34 )
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hide Recent research papers ( 4 )
Neumüller et al., 2011, Cell Stem Cell 8(5): 580--593
Genome-Wide Analysis of Self-Renewal in Drosophila Neural Stem Cells by Transgenic RNAi. [FBrf0213621]
Blanco et al., 2010, BMC Dev. Biol. 10: 94
Gene expression following induction of regeneration in Drosophila wing imaginal discs. Expression profile of regenerating wing discs. [FBrf0211812]
Fernández-Ayala et al., 2010, PLoS ONE 5(1): e8549
Gene expression in a Drosophila model of mitochondrial disease. [FBrf0209705]
Saulière et al., 2010, Nat. Struct. Mol. Biol. 17(10): 1269--1271
The exon junction complex differentially marks spliced junctions. [FBrf0212018]