Gene model reviewed during 5.45
Interacts (via N-terminus) with DZIP1.
The C-terminus orients towards the microtubules and the N-terminus orients towards the membrane in a 9-fold symmetric manner.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Cep290 using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\Cep290 in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for identity of: Cep290 CG13889
cep290 localises to the transition zone at the tip of the mother centriole in sensory cilia.