Gene Dmel\CG2199

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General Information

Symbol

Dmel\CG2199

Species

D. melanogaster

Name

Annotation symbol

CG2199

Feature type

protein_coding_gene

FlyBase ID

FBgn0035213

Gene Model Status

Current

Stock availability

3 publicly available

Genomic Location

Chromosome (arm)

Recombination map

Cytogenetic map

61F7-61F7

Sequence location

3L:1,339,457..1,342,403 [-]

Genomic Maps

Select View:

modENCODE GBrowse

Summary Information

Automatically generated summary

See sections below for more information

This gene is referred to in FlyBase by the symbol Dmel\CG2199 (FBgn0035213). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function: zinc ion binding; nucleic acid binding. The biological processes in which it is involved are not known. 3 alleles are reported. The phenotype of these alleles is annotated with: trichogen cell. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Zinc finger, C2H2; Zinc finger, C2H2-like; Zinc finger, C2H2-type/integrase, DNA-binding. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression. Peak expression observed within 06-12 hour embryonic stages. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: larval central nervous system, adult ovary, adult male accessory gland. Comments on Affy2 ProbeSet: ProbeSet 1633717_a_at completely aligns to an exonic region common to each of the 2 FlyBase-annotated transcript isoforms of CG2199. Gene sequence location is 3L:1339457..1342403.

Recent Updates

Description

What does this section display?

This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms).

What does this section not display?

This section does not currently display links that were removed or gene model changes.

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FB2011_10

Controlled Vocabulary Terms

day 6 of adulthood

day 5 of adulthood

male

day 7 of adulthood

spermatozoon

FB2012_01

Sequence features

BKN24362

HFA08558

All updates

Click here to see a list of all updates to this record from FB2010_08 and on.

Detailed Mapping Data

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

61F7-61F7

Limits computationally determined from genome sequence between P{PZ}l(3)02640⁰²⁶⁴⁰ and P{EP}rho^EP3704&P{PZ}l(3)06226⁰⁶²²⁶

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

Left of (cM)

Right of (cM)

Notes

Gene Model & Products

Please see the GBrowse view of Dmel\CG2199 for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Comments on Gene Model

DGC clone appears problematic (LD32068): incomplete CDS.

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Associated CDS (aa)

CG2199-RA

FBtr0072722

NM_138260

2847

724

CG2199-RB

FBtr0072721

NM_167873

2579

733

Additional Transcript Data & Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

RefSeq ID

GenBank protein

CG2199-PA

FBpp0072606

80.9

724

8.82

NP_612104

AAF47485

CG2199-PB

FBpp0072605

82.0

733

8.77

NP_728599

AAN11474

Additional Polypeptide Data & Comments

Reported size (kDa)

Comments

External Data

Linkouts

Crossreferences

InterPro domains - A database of protein families, domains, and functional sites

•

Zinc finger, C2H2 (IPR007087)

Zinc finger, C2H2-like (IPR015880)

Zinc finger, C2H2-type/integrase, DNA-binding (IPR013087)

Sequences Consistent with the Gene Model

DDBJ /
EMBL /
GenBank

DNA sequence

Protein sequence

Name

Q8IRH5

Mapped Features

Mapped Features have been reorganized, please see this article for details.

Additional mapped features and mutations can be found on GBrowse or related reports.

Type

Symbol & Location

Additional Notes

References

External Data

Linkouts

Crossreferences

Expression Data

Transcript Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Notes

Polypeptide Expression

mass spectroscopy

Stage

Tissue/Position (including subcellular localization)

Reference

day 5 of adulthood & male -- day 7 of adulthood & male

spermatozoon

(Wasbrough et al., 2010)

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Notes

High-Throughput Expression Data

Untitled Document detailed view

See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.

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modENCODE Temporal Expression Data (Graveley et al., 2011)
FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)

Expression Clusters

A cluster of genes with similar mRNA expression dynamics across development.

(The modENCODE Consortium, 2010)

mE2_34_mRNA_expression_cluster_08

External Data & Images

Linkouts

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

•

FBgn0035213

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

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CG2199-RB

FlyExpress - Embryonic expression images (BDGP data)

•

Show all FlyExpress processed images for CG2199

Alleles & Phenotypes

Summary of Allele Phenotypes

Lethality

Allele

viable, with Scer\GAL4^pnr-MD237

CG2199^GD9748

Other Phenotypes

Allele

visible, with Scer\GAL4^pnr-MD237

CG2199^GD9748

Phenotype manifest in

Allele

trichogen cell, with Scer\GAL4^pnr-MD237

CG2199^GD9748

Classical Alleles ( 1 )

For All Classical Alleles Show

Allele of CG2199	Class	Mutagen	Stocks	Known lesion
CG2199^c02129		piggyBac transposase	1	--

Alleles Carried on Transgenic Constructs ( 2 )

For All Alleles Carried on Transgenic Constructs Show

Allele of CG2199	Class	Mutagen	Stocks	Known lesion
CG2199^GD9748		in vitro construct - RNAi in vitro construct - regulatory fusion	1	Yes
CG2199^JF02428		in vitro construct - RNAi in vitro construct - regulatory fusion	1	Yes

Aneuploid Aberrations

Transgenic Constructs & Insertions

Transgenic Constructs

Type of construct

Name

Expression data

UAS construct

P{GD9748}

P{TRiP.JF02428}

Insertions

Type of insertions

Name

Expression data

miscellaneous insertions

PBac{PB}CG2199^c02129

insertion of mobile activating element

P{EPg}HP31858

Gene Ontology: Function, Process & Cellular Component ( 3 unique terms )

Terms Based on Experimental Evidence ( 0 terms )

Terms Based on Predictions or Assertions ( 3 terms )

Molecular Function

CV term

Evidence

References

nucleic acid binding

inferred from electronic annotation with InterPro:IPR013087

(FlyBase Curators et al., 2004-)

zinc ion binding

inferred from electronic annotation with InterPro:IPR007087, InterPro:IPR015880

(FlyBase Curators et al., 2004-)

Biological Process ( 0 terms)

Cellular Component

CV term

Evidence

References

intracellular

inferred from electronic annotation with InterPro:IPR007087, InterPro:IPR015880

(FlyBase Curators et al., 2004-)

Sequence Ontology: Class of Gene

nuclear_gene

protein_coding_gene

Interactions & Pathways

Summary of Physical Interactions

Protein-protein

Interacting group

Assay

References

Summary of Genetic Interactions

Interacts with

Please look at the allele data for full details of the genetic interactions

CG2199 allele

Gene

References

External Data

Linkouts

BioGRID - A database of protein and genetic interactions

•

63701

DroID - A comprehensive database of gene and protein interactions.

•

FBgn0035213

InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets.

•

38159

Orthologs

Genome-wide drosophilid orthologs

Dana\GF10061

Dere\GG14604

Dgri\GH16227

Dmoj\GI13373

Dper\GL16070

Dpse\GA15296

Dsec\GM14218

Dsim\GD13481

Dvir\GJ13203

Dwil\GK12499

Dyak\GE20965

Curated drosophilid orthologs

Dpse\GA15296

Linkouts

OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs.

•

Stocks & Reagents

Stocks Listed in FlyBase ( 3 )

Bloomington

27082

y¹ v¹; P{TRiP.JF02428}attP2

Harvard

PBac{PB}CG2199^c02129

VDRC

v20839

w¹¹¹⁸; P{GD9748}v20839

Genomic Clones ( 1 )

BACR17K17

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones ( 64 )

Please Note

This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA Clones, Fully Sequenced

BDGP DGC clones

Other clones

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi & Array Information

Linkouts

DRSC - Results from RNAi screens.

•

FBgn0035213

GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents

•

38159

Antibody Information

Other Information

Discoverer

Etymology

Identification

Relationship to Other Genes

Source for database identity of

Source for database merge of

Additional comments

FlyBase curator comment: the insertion in the "f06926" Exelixis line (PBac{WH}Ptp61F^f06926) was originally assigned to the CG2199 gene in FBrf0179797, resulting in the "CG2199^f06926" (FBal0161936) allele. However, FBrf0184340 shows that the insertion is actually within Ptp61F.

(Bloomington Drosophila Stock Center, 2004.11.6)

Other Comments

External Crossreferences & Linkouts

Sequence Crossreferences

RefSeq (Transcripts)

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RefSeq (Proteins)

•

DDBJ / EMBL / GenBank

•

Entrez Gene - A searchable database of RefSeq genes.

•