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Gene Dmel\CG7852

General Information
Symbol	Dmel\CG7852	Species	D. melanogaster
Name		Annotation symbol	CG7852
Feature type	protein_coding_gene	FlyBase ID	FBgn0035229
Gene Model Status	Current	Stock availability	4 publicly available
Genomic Location
Chromosome (arm)	3L	Recombination map
Cytogenetic map	62A3-62A3	Sequence location	3L:1,537,149..1,544,826 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG7852 (FBgn0035229). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 5 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. Protein features are: DENN; Lipase/lipooxygenase, PLAT/LH2; Lipoxygenase, LH2; RUN; dDENN; uDENN. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed within 00-18 hour embryonic stages, at stages throughout the pupal period, in stages of adults of both sexes. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult testis, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1623043_s_at completely aligns to an exonic region common to each of the 3 FlyBase-annotated transcript isoforms of CG7852. Gene sequence location is 3L:1537149..1544826.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2011_10
FB2012_01	Sequence features HFA08598 BKN21530
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 62A3-62A3   Limits computationally determined from genome sequence between P{EP}rhoEP3704&P{PZ}l(3)0622606226 and P{PZ}dlt04276
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG7852 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG7852-RA FBtr0072735  NM_139363   5381   1449 CG7852-RB FBtr0072736  NM_167890   5385   1449 CG7852-RC FBtr0072737  NM_206232   5600   817
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG7852-PA   FBpp0072618   163.4   1449   8.28     NP_647620   AAF47507 CG7852-PB   FBpp0072619   163.4   1449   8.28     NP_728624   AAN11487 CG7852-PC   FBpp0072620   91.2   817   7.25     NP_995954   AAS64930
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Lipoxygenase, LH2 (IPR001024) DENN (IPR001194) RUN (IPR004012) dDENN (IPR005112) uDENN (IPR005113) Lipase/lipooxygenase, PLAT/LH2 (IPR008976)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE014296 AAF47507   AE014296 AAN11487   AE014296 AAS64930   AY128463 AAM75056   BF492890   BF492891   BF494979   BF496317   BF499345   BF504090   BF506085   BG635295   BI213386   BI368527   BI484422   CK658116   CK661458   CO279372   CO293745   CO328284   CO338923   CZ469307   EC061278   EC075023   EC086775   EC210455   EC250469   EC254079   EC257635   ES690509   EV577991   GH950310   GH954517   GH955218   GH963482   GH970010   GH975905   GH983464
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q8MQP7 Q9W0E1
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0035229    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0035229 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed within 00-18 hour embryonic stages, at stages throughout the pupal period, in stages of adults of both sexes. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0035229 expression level Developmental Stage   Expression Level embryo 00-02hr    2973 embryo 02-04hr    1329 embryo 04-06hr    1710 embryo 06-08hr    1550 embryo 08-10hr    1342 embryo 10-12hr    1383 embryo 12-14hr    1208 embryo 14-16hr    1418 embryo 16-18hr    1260 embryo 18-20hr    1287 embryo 20-22hr    918 embryo 22-24hr    975 larva L1    724 larva L2    640 larva L3 12hr old    420 larva L3 puffstage 1-2    484 larva L3 puffstage 3-6    878 larva L3 puffstage 7-9    1000 white prepupae new    1147 white prepupae 12hr    1425 white prepupae 24hr    1564 pupae 2d postWPP    1699 pupae 3d postWPP    1388 pupae 4d postWPP    1433 adult male 01day    1629 adult male 05day    1789 adult male 30day    1565 adult female 01day    1616 adult female 05day    2396 adult female 30day    2399 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (2973) embryo 02-04hr  (1329) embryo 04-06hr  (1710) embryo 06-08hr  (1550) embryo 08-10hr  (1342) embryo 10-12hr  (1383) embryo 12-14hr  (1208) embryo 14-16hr  (1418) embryo 16-18hr  (1260) embryo 18-20hr  (1287) embryo 20-22hr  (918) embryo 22-24hr  (975) larva L1  (724) larva L2  (640) larva L3 12hr old  (420) larva L3 puffstage 1-2  (484) larva L3 puffstage 3-6  (878) larva L3 puffstage 7-9  (1000) white prepupae new  (1147) white prepupae 12hr  (1425) white prepupae 24hr  (1564) pupae 2d postWPP  (1699) pupae 3d postWPP  (1388) pupae 4d postWPP  (1433) adult male 01day  (1629) adult male 05day  (1789) adult male 30day  (1565) adult female 01day  (1616) adult female 05day  (2396) adult female 30day  (2399) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (2973) embryo 02-04hr    1329 embryo 04-06hr  (1710) embryo 06-08hr  (1550) embryo 08-10hr    1342 embryo 10-12hr    1383 embryo 12-14hr    1208 embryo 14-16hr  1418 embryo 16-18hr    1260 embryo 18-20hr    1287 embryo 20-22hr    918 embryo 22-24hr    975 larva L1    724 larva L2    640 larva L3 12hr old    420 larva L3 puffstage 1-2    484 larva L3 puffstage 3-6    878 larva L3 puffstage 7-9    1000 white prepupae new    1147 white prepupae 12hr  1425 white prepupae 24hr  (1564) pupae 2d postWPP  (1699) pupae 3d postWPP    1388 pupae 4d postWPP  1433 adult male 01day  (1629) adult male 05day  (1789) adult male 30day  (1565) adult female 01day  (1616) adult female 05day  (2396) adult female 30day  (2399) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    2973 embryo 02-04hr    1329 embryo 04-06hr    1710 embryo 06-08hr    1550 embryo 08-10hr    1342 embryo 10-12hr    1383 embryo 12-14hr    1208 embryo 14-16hr    1418 embryo 16-18hr    1260 embryo 18-20hr    1287 embryo 20-22hr    918 embryo 22-24hr    975 larva L1    724 larva L2    640 larva L3 12hr old    420 larva L3 puffstage 1-2    484 larva L3 puffstage 3-6    878 larva L3 puffstage 7-9    1000 white prepupae new    1147 white prepupae 12hr    1425 white prepupae 24hr    1564 pupae 2d postWPP    1699 pupae 3d postWPP    1388 pupae 4d postWPP    1433 adult male 01day    1629 adult male 05day    1789 adult male 30day    1565 adult female 01day    1616 adult female 05day    2396 adult female 30day    2399 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    2973 embryo 02-04hr    1329 embryo 04-06hr    1710 embryo 06-08hr    1550 embryo 08-10hr    1342 embryo 10-12hr    1383 embryo 12-14hr    1208 embryo 14-16hr    1418 embryo 16-18hr    1260 embryo 18-20hr    1287 embryo 20-22hr    918 embryo 22-24hr    975 larva L1    724 larva L2    640 larva L3 12hr old    420 larva L3 puffstage 1-2    484 larva L3 puffstage 3-6    878 larva L3 puffstage 7-9    1000 white prepupae new    1147 white prepupae 12hr    1425 white prepupae 24hr    1564 pupae 2d postWPP    1699 pupae 3d postWPP    1388 pupae 4d postWPP    1433 adult male 01day    1629 adult male 05day    1789 adult male 30day    1565 adult female 01day    1616 adult female 05day    2396 adult female 30day    2399 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0035229 expression level Developmental Stage   Expression Level embryo 00-02hr    2973 embryo 02-04hr    1329 embryo 04-06hr    1710 embryo 06-08hr    1550 embryo 08-10hr    1342 embryo 10-12hr    1383 embryo 12-14hr    1208 embryo 14-16hr    1418 embryo 16-18hr    1260 embryo 18-20hr    1287 embryo 20-22hr    918 embryo 22-24hr    975 larva L1    724 larva L2    640 larva L3 12hr old    420 larva L3 puffstage 1-2    484 larva L3 puffstage 3-6    878 larva L3 puffstage 7-9    1000 white prepupae new    1147 white prepupae 12hr    1425 white prepupae 24hr    1564 pupae 2d postWPP    1699 pupae 3d postWPP    1388 pupae 4d postWPP    1433 adult male 01day    1629 adult male 05day    1789 adult male 30day    1565 adult female 01day    1616 adult female 05day    2396 adult female 30day    2399 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (2973) embryo 02-04hr  (1329) embryo 04-06hr  (1710) embryo 06-08hr  (1550) embryo 08-10hr  (1342) embryo 10-12hr  (1383) embryo 12-14hr  (1208) embryo 14-16hr  (1418) embryo 16-18hr  (1260) embryo 18-20hr  (1287) embryo 20-22hr  (918) embryo 22-24hr  (975) larva L1  (724) larva L2  (640) larva L3 12hr old  (420) larva L3 puffstage 1-2  (484) larva L3 puffstage 3-6  (878) larva L3 puffstage 7-9  (1000) white prepupae new  (1147) white prepupae 12hr  (1425) white prepupae 24hr  (1564) pupae 2d postWPP  (1699) pupae 3d postWPP  (1388) pupae 4d postWPP  (1433) adult male 01day  (1629) adult male 05day  (1789) adult male 30day  (1565) adult female 01day  (1616) adult female 05day  (2396) adult female 30day  (2399) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (2973) embryo 02-04hr    1329 embryo 04-06hr  1710 embryo 06-08hr  1550 embryo 08-10hr    1342 embryo 10-12hr    1383 embryo 12-14hr    1208 embryo 14-16hr  1418 embryo 16-18hr    1260 embryo 18-20hr    1287 embryo 20-22hr    918 embryo 22-24hr    975 larva L1    724 larva L2    640 larva L3 12hr old    420 larva L3 puffstage 1-2    484 larva L3 puffstage 3-6    878 larva L3 puffstage 7-9    1000 white prepupae new    1147 white prepupae 12hr  1425 white prepupae 24hr  1564 pupae 2d postWPP  1699 pupae 3d postWPP    1388 pupae 4d postWPP  1433 adult male 01day  1629 adult male 05day  1789 adult male 30day  1565 adult female 01day  1616 adult female 05day  2396 adult female 30day  2399 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    2973 embryo 02-04hr    1329 embryo 04-06hr    1710 embryo 06-08hr    1550 embryo 08-10hr    1342 embryo 10-12hr    1383 embryo 12-14hr    1208 embryo 14-16hr    1418 embryo 16-18hr    1260 embryo 18-20hr    1287 embryo 20-22hr    918 embryo 22-24hr    975 larva L1    724 larva L2    640 larva L3 12hr old    420 larva L3 puffstage 1-2    484 larva L3 puffstage 3-6    878 larva L3 puffstage 7-9    1000 white prepupae new    1147 white prepupae 12hr    1425 white prepupae 24hr    1564 pupae 2d postWPP    1699 pupae 3d postWPP    1388 pupae 4d postWPP    1433 adult male 01day    1629 adult male 05day    1789 adult male 30day    1565 adult female 01day    1616 adult female 05day    2396 adult female 30day    2399 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    2973 embryo 02-04hr    1329 embryo 04-06hr    1710 embryo 06-08hr    1550 embryo 08-10hr    1342 embryo 10-12hr    1383 embryo 12-14hr    1208 embryo 14-16hr    1418 embryo 16-18hr    1260 embryo 18-20hr    1287 embryo 20-22hr    918 embryo 22-24hr    975 larva L1    724 larva L2    640 larva L3 12hr old    420 larva L3 puffstage 1-2    484 larva L3 puffstage 3-6    878 larva L3 puffstage 7-9    1000 white prepupae new    1147 white prepupae 12hr    1425 white prepupae 24hr    1564 pupae 2d postWPP    1699 pupae 3d postWPP    1388 pupae 4d postWPP    1433 adult male 01day    1629 adult male 05day    1789 adult male 30day    1565 adult female 01day    1616 adult female 05day    2396 adult female 30day    2399 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0035229    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0035229 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult testis, larval/adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0035229 expression level Tissue   Expression Level Larval Central Nervous System    373.35 Larval Midgut    55 Larval Hindgut    69.4 Larval Malpighian Tubules    97.9 Larval Fat Body    116.9 Larval Salivary Gland    194.4 Larval Trachea    120.025 Larval Carcass    132.075 Adult Head    219.4 Adult Eye    189.275 Adult Brain    476 Adult Thoracic-Abdominal Ganglion    464.6 Adult Crop    105.9 Adult Midgut    51.5 Adult Hindgut    81.3 Adult Malpighian Tubules    67.6 Adult Fat Body    194.3 Adult Salivary Gland    182.5 Adult Heart    113.05 Adult VirginFemale Spermatheca    171.3 Adult InseminatedFemale Spermatheca    174.5 Adult Ovary    441.9 Adult Testis    104.6 Adult Male Accessory Gland    69.1 Adult Carcass    171 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    373.35 Larval Midgut    55 Larval Hindgut    69.4 Larval Malpighian Tubules    97.9 Larval Fat Body    116.9 Larval Salivary Gland    194.4 Larval Trachea    120.025 Larval Carcass    132.075 Adult Head    219.4 Adult Eye    189.275 Adult Brain    476 Adult Thoracic-Abdominal Ganglion    464.6 Adult Crop    105.9 Adult Midgut    51.5 Adult Hindgut    81.3 Adult Malpighian Tubules    67.6 Adult Fat Body    194.3 Adult Salivary Gland    182.5 Adult Heart    113.05 Adult VirginFemale Spermatheca    171.3 Adult InseminatedFemale Spermatheca    174.5 Adult Ovary    441.9 Adult Testis    104.6 Adult Male Accessory Gland    69.1 Adult Carcass    171 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    373.35 Larval Midgut    55 Larval Hindgut    69.4 Larval Malpighian Tubules    97.9 Larval Fat Body    116.9 Larval Salivary Gland    194.4 Larval Trachea    120.025 Larval Carcass    132.075 Adult Head    219.4 Adult Eye    189.275 Adult Brain    476 Adult Thoracic-Abdominal Ganglion    464.6 Adult Crop    105.9 Adult Midgut    51.5 Adult Hindgut    81.3 Adult Malpighian Tubules    67.6 Adult Fat Body    194.3 Adult Salivary Gland    182.5 Adult Heart    113.05 Adult VirginFemale Spermatheca    171.3 Adult InseminatedFemale Spermatheca    174.5 Adult Ovary    441.9 Adult Testis    104.6 Adult Male Accessory Gland    69.1 Adult Carcass    171 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    373.35 Larval Midgut    55 Larval Hindgut    69.4 Larval Malpighian Tubules    97.9 Larval Fat Body    116.9 Larval Salivary Gland    194.4 Larval Trachea    120.025 Larval Carcass    132.075 Adult Head    219.4 Adult Eye    189.275 Adult Brain    476 Adult Thoracic-Abdominal Ganglion    464.6 Adult Crop    105.9 Adult Midgut    51.5 Adult Hindgut    81.3 Adult Malpighian Tubules    67.6 Adult Fat Body    194.3 Adult Salivary Gland    182.5 Adult Heart    113.05 Adult VirginFemale Spermatheca    171.3 Adult InseminatedFemale Spermatheca    174.5 Adult Ovary    441.9 Adult Testis    104.6 Adult Male Accessory Gland    69.1 Adult Carcass    171 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0035229 expression level Tissue   Expression Level Larval Central Nervous System    373.35 Larval Midgut    55 Larval Hindgut    69.4 Larval Malpighian Tubules    97.9 Larval Fat Body    116.9 Larval Salivary Gland    194.4 Larval Trachea    120.025 Larval Carcass    132.075 Adult Head    219.4 Adult Eye    189.275 Adult Brain    476 Adult Thoracic-Abdominal Ganglion    464.6 Adult Crop    105.9 Adult Midgut    51.5 Adult Hindgut    81.3 Adult Malpighian Tubules    67.6 Adult Fat Body    194.3 Adult Salivary Gland    182.5 Adult Heart    113.05 Adult VirginFemale Spermatheca    171.3 Adult InseminatedFemale Spermatheca    174.5 Adult Ovary    441.9 Adult Testis    104.6 Adult Male Accessory Gland    69.1 Adult Carcass    171 Expression Level Scale  None   Low   Moderate   High  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    373.35 Larval Midgut    55 Larval Hindgut    69.4 Larval Malpighian Tubules    97.9 Larval Fat Body    116.9 Larval Salivary Gland    194.4 Larval Trachea    120.025 Larval Carcass    132.075 Adult Head    219.4 Adult Eye    189.275 Adult Brain    476 Adult Thoracic-Abdominal Ganglion    464.6 Adult Crop    105.9 Adult Midgut    51.5 Adult Hindgut    81.3 Adult Malpighian Tubules    67.6 Adult Fat Body    194.3 Adult Salivary Gland    182.5 Adult Heart    113.05 Adult VirginFemale Spermatheca    171.3 Adult InseminatedFemale Spermatheca    174.5 Adult Ovary    441.9 Adult Testis    104.6 Adult Male Accessory Gland    69.1 Adult Carcass    171 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    373.35 Larval Midgut    55 Larval Hindgut    69.4 Larval Malpighian Tubules    97.9 Larval Fat Body    116.9 Larval Salivary Gland    194.4 Larval Trachea    120.025 Larval Carcass    132.075 Adult Head    219.4 Adult Eye    189.275 Adult Brain    476 Adult Thoracic-Abdominal Ganglion    464.6 Adult Crop    105.9 Adult Midgut    51.5 Adult Hindgut    81.3 Adult Malpighian Tubules    67.6 Adult Fat Body    194.3 Adult Salivary Gland    182.5 Adult Heart    113.05 Adult VirginFemale Spermatheca    171.3 Adult InseminatedFemale Spermatheca    174.5 Adult Ovary    441.9 Adult Testis    104.6 Adult Male Accessory Gland    69.1 Adult Carcass    171 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    373.35 Larval Midgut    55 Larval Hindgut    69.4 Larval Malpighian Tubules    97.9 Larval Fat Body    116.9 Larval Salivary Gland    194.4 Larval Trachea    120.025 Larval Carcass    132.075 Adult Head    219.4 Adult Eye    189.275 Adult Brain    476 Adult Thoracic-Abdominal Ganglion    464.6 Adult Crop    105.9 Adult Midgut    51.5 Adult Hindgut    81.3 Adult Malpighian Tubules    67.6 Adult Fat Body    194.3 Adult Salivary Gland    182.5 Adult Heart    113.05 Adult VirginFemale Spermatheca    171.3 Adult InseminatedFemale Spermatheca    174.5 Adult Ovary    441.9 Adult Testis    104.6 Adult Male Accessory Gland    69.1 Adult Carcass    171 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    219.4   NA  Eye    189.275   NA  Brain    476   373.35  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    464.6   NA  Crop    105.9   55  Midgut    51.5   69.4  Hindgut    81.3   97.9  Malpighian Tubules    67.6   116.9  Fat Body    194.3   194.4  Salivary Gland    182.5   NA  Heart    113.05   120.025  Trachea    NA   NA  VirginFemale Spermatheca    171.3   NA  InseminatedFemale Spermatheca    174.5   NA  Ovary    441.9   NA  Testis    104.6   NA  Male Accessory Gland    69.1   132.075  Carcass    171 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_27
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0035229 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG7852-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable CG7852124 viable, with Scer\GAL4pnr-MD237 CG7852GD1579 Phenotype manifest in Allele
Classical Alleles ( 3 )
For All Classical Alleles Show
Allele of CG7852 Class Mutagen Stocks Known lesion CG7852c04511 piggyBac transposase 1 -- CG7852EY05553 1 -- CG7852124 Delta2-3 0 Yes
Alleles Carried on Transgenic Constructs ( 2 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG7852 Class Mutagen Stocks Known lesion CG7852GD1579 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG7852KK101479 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes
Aneuploid Aberrations
Disrupted in	Df(3L)Exel6087 (Ryder, 2004.4.26)
Not disrupted in	Df(3L)Cct1124 (Gupta and Schupbach, 2003)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD1579} NA P{KK101479} NA
Insertions
	Type of insertions Name Expression data insertion of mobile activating element P{EPgy2}CG7852EY05553 NA miscellaneous insertions PBac{PB}CG7852c04511 NA
Gene Ontology: Function, Process & Cellular Component ( 0 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 0 terms )
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG7852 allele Gene References
External Data
Linkouts	DroID - A comprehensive database of gene and protein interactions. • FBgn0035229 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 38178
Orthologs
Genome-wide drosophilid orthologs	Dana\GF24770 Dere\GG14796 Dgri\GH14502 Dmoj\GI13278 Dper\GL22606 Dpse\GA20634 Dsec\GM14418 Dsim\GD13622 Dvir\GJ12046 Dwil\GK12563 Dyak\GE21158
Curated drosophilid orthologs	Dpse\GA20634
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL009495-PA Aedes aegypti (mosquito) AGAP011351-PA Anopheles gambiae (mosquito) XP_395592.3 Apis mellifera (honey bee) 97169 Branchiostoma floridae (lancelet) XP_001896273.1 Brugia malayi (roundworm nematode) BGIBMGA000975-PA Bombyx mori (silk worm) ENSBTAP00000027075 Bos taurus (bovine) CBP32907 Caenorhabditis briggsae (nematode) CE31684 Caenorhabditis elegans (worm) ENSCAFP00000015705 Canis familiaris (dog) CPIJ006771 Culex pipens (mosquito) ENSCPOP00000004970 Cavia porcellus (guinea pig) RP10155 Caenorhabditis remanei (nematode) 228570 Capitella spl (polychaete worm) 219947 Daphnia pulex (daphnia) ENSDARP00000060544 Danio rerio (zebra fish) ENSECAP00000010861 Equus caballus (horse) ENSGACP00000020681 Gymnopilus aculeatus (mushroom) ENSGALP00000021082 Gallus gallus (chicken) 108840 Hypsipyla robusta (cedar shoot borer) ENSP00000328524 Homo sapiens (human) 232739 Lottia gigantea (owl limpet) 22491 Monocosta brevicollis (choanoflagellate) ENSMODP00000038134 Monodelphis domestica (gray opossum) ENSMMUP00000027837 Macaca mulatta (rhesus monkey) ENSMUSP00000107182 Mus musculus (house mouse) ENSOANP00000004945 Ornithorynchus anatinus (platypus) ENSORLP00000008836 Oryzias latipes (japanese killifish) PHUM003894-PA Pediculus humanus (human body louse) ENSPPYP00000005020 Pongo pygmaeus (orangutan) ENSPTRP00000005844 Pan troglodytes (chimpanzee) ENSRNOP00000017485 Rattus norvegicus (norway rat) Smp_139090.1 Schistosoma mansoni (trematode parasite) XP_781573.2 Strongylocentrotus purpuratus (purple sea urchin) 61833 Trichoplax adhaerens (metazoa) ENSTNIP00000001279 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000044611 Takifugu rubripes (pufferfish Takifugu) ENSXETP00000009648 Xenopus tropicalis (frog) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB15119 NV50744 LH24269 FBgn0238434 FBgn0214573 FBgn0199298 FBgn0185332 FBgn0169342 JGI_V11_219947 FBgn0080628 FBgn0160197 FBgn0136035 FBgn0121978 FBgn0107052 FBgn0101763 CPIJ006771 BGIBMGA000975 GB16813 AGAP011351 AAEL009495 PHUM085450 GLEAN_07707
Stocks & Reagents
Stocks Listed in FlyBase ( 4 )
Bloomington	15455 y1 w67c23; P{EPgy2}CG7852EY05553
Harvard	- PBac{PB}CG7852c04511
VDRC	v103582 P{KK101479}VIE-260B v7178 w1118; P{GD1579}v7178
Genomic Clones ( 1 )
	BACR27O01 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 31 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	RE18773
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT03773 AT05376 AT08467 AT10082 AT13885 AT31824 LP14696 LP20981 RE54512 RE67522
Other clones	20133 36592 70908 74736 177026 214277.25 214403.23 AT01262 Dmel_dig_017426_0653_2522 EK134160 EK204442 EP00320 EP08913 RP004100602 RP004112945 RP004170387 RP004209609 RP004332061 RP004433436 RP004513974
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0035229 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 38178
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_139363 NM_167890 NM_206232 RefSeq (Proteins) • NP_647620 NP_728624 NP_995954 DDBJ / EMBL / GenBank • AAF47507 AAM75056 AAN11487 AAS64930 AY128463 BI213386 CZ469307 Entrez Gene - A searchable database of RefSeq genes. • 38178 UniProtKB/TrEMBL • Q8MQP7 Q9W0E1
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Lipoxygenase, LH2 (IPR001024) DENN (IPR001194) RUN (IPR004012) dDENN (IPR005112) uDENN (IPR005113) Lipase/lipooxygenase, PLAT/LH2 (IPR008976)
Linkouts
	DroID - A comprehensive database of gene and protein interactions. • FBgn0035229 DRSC - Results from RNAi screens. • FBgn0035229 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0035229 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG7852-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0035229 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 38178 InParanoid A subset of ortholog calls from InParanoid. • AAEL009495-PA Aedes aegypti (mosquito) AGAP011351-PA Anopheles gambiae (mosquito) XP_395592.3 Apis mellifera (honey bee) 97169 Branchiostoma floridae (lancelet) XP_001896273.1 Brugia malayi (roundworm nematode) BGIBMGA000975-PA Bombyx mori (silk worm) ENSBTAP00000027075 Bos taurus (bovine) CBP32907 Caenorhabditis briggsae (nematode) CE31684 Caenorhabditis elegans (worm) ENSCAFP00000015705 Canis familiaris (dog) CPIJ006771 Culex pipens (mosquito) ENSCPOP00000004970 Cavia porcellus (guinea pig) RP10155 Caenorhabditis remanei (nematode) 228570 Capitella spl (polychaete worm) 219947 Daphnia pulex (daphnia) ENSDARP00000060544 Danio rerio (zebra fish) ENSECAP00000010861 Equus caballus (horse) ENSGACP00000020681 Gymnopilus aculeatus (mushroom) ENSGALP00000021082 Gallus gallus (chicken) 108840 Hypsipyla robusta (cedar shoot borer) ENSP00000328524 Homo sapiens (human) 232739 Lottia gigantea (owl limpet) 22491 Monocosta brevicollis (choanoflagellate) ENSMODP00000038134 Monodelphis domestica (gray opossum) ENSMMUP00000027837 Macaca mulatta (rhesus monkey) ENSMUSP00000107182 Mus musculus (house mouse) ENSOANP00000004945 Ornithorynchus anatinus (platypus) ENSORLP00000008836 Oryzias latipes (japanese killifish) PHUM003894-PA Pediculus humanus (human body louse) ENSPPYP00000005020 Pongo pygmaeus (orangutan) ENSPTRP00000005844 Pan troglodytes (chimpanzee) ENSRNOP00000017485 Rattus norvegicus (norway rat) Smp_139090.1 Schistosoma mansoni (trematode parasite) XP_781573.2 Strongylocentrotus purpuratus (purple sea urchin) 61833 Trichoplax adhaerens (metazoa) ENSTNIP00000001279 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000044611 Takifugu rubripes (pufferfish Takifugu) ENSXETP00000009648 Xenopus tropicalis (frog) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 38178 modMine - Data generated by the modENCODE project. • FBgn0035229 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB15119 NV50744 LH24269 FBgn0238434 FBgn0214573 FBgn0199298 FBgn0185332 FBgn0169342 JGI_V11_219947 FBgn0080628 FBgn0160197 FBgn0136035 FBgn0121978 FBgn0107052 FBgn0101763 CPIJ006771 BGIBMGA000975 GB16813 AGAP011351 AAEL009495 PHUM085450 GLEAN_07707
Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	CG7852 (Keleman et al., 2009.8.5)
Name Synonym
Secondary FlyBase IDs
References ( 17 )
Research paper	Gupta and Schupbach, 2003, Development 130(24): 6075--6087 Cct1, a phosphatidylcholine biosynthesis enzyme, is required for Drosophila oogenesis and ovarian morphogenesis. [FBrf0167510] Levivier et al., 2001, Biochem. biophys. Res. Commun. 287(3): 688--695 uDENN, DENN, and dDENN: indissociable domains in Rab and MAP kinases signaling pathways. [FBrf0155567]
Supplementary material	The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518]
Review	Callebaut et al., 2001, Trends Biochem. Sci. 26(2): 79--83 RUN domains: a new family of domains involved in Ras-like GTPase signaling. [FBrf0182627]
Personal communication to FlyBase	Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] FlyBase Curators et al., 2004-, Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. [FBrf0174215] Ryder, 2004.4.26, Exelixis CG deletion data. Exelixis CG deletion data. [FBrf0184335]
FlyBase analysis	FlyBase Curators, 2008, Insertion identifiers and alleles based on genomic location of insertions with respect to gene annotations. Insertion identifiers and alleles based on genomic location of insertions with respect to gene annotations. [FBrf0202955] FlyBase, 1992-, FlyBase curation FlyBase curation. [FBrf0105495]
Computer file	Gene Disruption Project members and Exelixis, 2005, Genomic mapping of Exelixis insertion collection. Genomic mapping of Exelixis insertion collection. [FBrf0184340] Gene Disruption Project members, 2001-, [title not yet available] [title not yet available] [FBrf0132177] BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. Berkeley Drosophila Genome Project. [FBrf0125078]
Automatic genome annotation	FamiliarityBreedsContempt, 1999.11, [Annotations performed at the Celera Jamboreee.] [Annotations performed at the Celera Jamboreee.] [FBrf0126705]
Curated genome annotation	Milshina, 1999.11, [Annotations performed at the Celera Jamboreee.] [Annotations performed at the Celera Jamboreee.] [FBrf0126686]