General Information Symbol Dmel\ CG1275Species D. melanogaster Name Annotation symbol CG1275 Feature type protein_coding_gene FlyBase ID FBgn0035321 Gene Model Status Current Stock availability 10 publicly
available Genomic Location Chromosome (arm) 3L Recombination map Cytogenetic map 62D4-62D4 Sequence location 3L:2,252,744..2,257,423 [-]
Genomic Maps
Summary Information Automatically generated summary
See sections below for more information This gene is referred to in FlyBase by the symbol
Dmel\CG1275 (FBgn0035321). It is a protein_coding_gene from
Drosophila melanogaster . Based on sequence similarity, it is predicted to have
molecular function : electron carrier activity. The
biological processes in which it is involved are not known.
15 alleles are reported . The
phenotype of these alleles is annotated with: mesothoracic tergum. It has
4 annotated transcripts and
4 annotated polypeptides .
Protein features are: Cytochrome b561, eukaryote; Cytochrome b561/ferric reductase transmembrane. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderate expression. Peak expression observed during late pupal stages. Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult central nervous system, adult crop, larval/adult Malpighian tubules, larval fat body, larval salivary gland, larval trachea, adult male reproductive system. Expression at moderate levels in the following post-embryonic organs or tissues: adult eye, larval central nervous system, larval/adult midgut, larval/adult hindgut, adult heart, adult fat body, adult salivary gland, adult female reproductive system, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1635256_s_at completely aligns to an exonic region common to each of the 4 FlyBase-annotated transcript isoforms of CG1275. Gene sequence location is
3L:2252744..2257423 .
User Contributed Data
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It currently only tracks new links between this FlyBase report and other
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FB2013_03
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Detailed Mapping Data
FlyBase Computed Cytological Location
Experimentally Determined Cytological Location
Experimentally Determined Recombination Data
Location Left of (cM) Right of (cM) Notes Gene Model & Products Comments on Gene
Model Gene model reviewed during 5.45
Low-frequency RNA-seq exon junction(s) not annotated.
Annotated transcripts do not represent all supported alternative splices within 5' UTR.
Transcript Data Annotated Transcripts Additional Transcript Data
& Comments Reported size (kB) Comments External Data Crossreferences
Polypeptide Data Annotated
Polypeptides Additional Polypeptide
Data & Comments Reported size (kDa) Comments External Data Linkouts Crossreferences
domains - A database of protein families, domains, and functional sites
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank UniProtKB/Swiss-Prot UniProtKB/TrEMBL Mapped Features Mapped Features have been reorganized, please
see this article for details. Additional mapped features and mutations can
be found on GBrowse or related reports. External Data Linkouts Crossreferences Expression Data Transcript ExpressionComment: maternally deposited
Additional Descriptive Data
CG1275 transcript is expressed at a moderate level in the CNS of late stage embryos.
CG1275 transcript is also expressed in
dimm -positive neurons in adults.
Marker for Subcellular Localization CV Term Polypeptide Expression
Additional Descriptive Data
Marker for Subcellular Localization (GO Cellular Component) Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference
FlyAtlas Anatomy Microarray
Linear, scaled to maximum expression level
Tissue
Expression Level
Larval Central Nervous System
305.925
Larval Midgut
446.5
Larval Hindgut
479.7
Larval Malpighian Tubules
1639.4
Larval Fat Body
936.7
Larval Salivary Gland
702
Larval Trachea
2176.25
Larval Carcass
453.2
Adult Head
647.5
Adult Eye
181.85
Adult Brain
1236.8
Adult Thoracic-Abdominal Ganglion
1143.8
Adult Crop
1835.9
Adult Midgut
365.9
Adult Hindgut
331.7
Adult Malpighian Tubules
1379.8
Adult Fat Body
119
Adult Salivary Gland
346.5
Adult Heart
272.275
Adult VirginFemale Spermatheca
223.1
Adult InseminatedFemale Spermatheca
266.2
Adult Ovary
476.6
Adult Testis
560.3
Adult Male Accessory Gland
1058.7
Adult Carcass
305.8
Expression Level Scale
None
Low
Moderate
High
Very high
Linear, scaled to Moderate expression
Tissue
Expression Level
Larval Central Nervous System
305.925
Larval Midgut
446.5
Larval Hindgut
479.7
Larval Malpighian Tubules
(1639.4)
Larval Fat Body
(936.7)
Larval Salivary Gland
(702)
Larval Trachea
(2176.25)
Larval Carcass
453.2
Adult Head
(647.5)
Adult Eye
181.85
Adult Brain
(1236.8)
Adult Thoracic-Abdominal Ganglion
(1143.8)
Adult Crop
(1835.9)
Adult Midgut
365.9
Adult Hindgut
331.7
Adult Malpighian Tubules
(1379.8)
Adult Fat Body
119
Adult Salivary Gland
346.5
Adult Heart
272.275
Adult VirginFemale Spermatheca
223.1
Adult InseminatedFemale Spermatheca
266.2
Adult Ovary
476.6
Adult Testis
(560.3)
Adult Male Accessory Gland
(1058.7)
Adult Carcass
305.8
Expression Level Scale
None
Low
Moderate
High
Linear, scaled to High level expression
Tissue
Expression Level
Larval Central Nervous System
305.925
Larval Midgut
446.5
Larval Hindgut
479.7
Larval Malpighian Tubules
(1639.4)
Larval Fat Body
936.7
Larval Salivary Gland
702
Larval Trachea
(2176.25)
Larval Carcass
453.2
Adult Head
647.5
Adult Eye
181.85
Adult Brain
(1236.8)
Adult Thoracic-Abdominal Ganglion
(1143.8)
Adult Crop
(1835.9)
Adult Midgut
365.9
Adult Hindgut
331.7
Adult Malpighian Tubules
(1379.8)
Adult Fat Body
119
Adult Salivary Gland
346.5
Adult Heart
272.275
Adult VirginFemale Spermatheca
223.1
Adult InseminatedFemale Spermatheca
266.2
Adult Ovary
476.6
Adult Testis
560.3
Adult Male Accessory Gland
1058.7
Adult Carcass
305.8
Expression Level Scale
None
Low
Moderate
High
Very high
Linear, scaled to Very high expression
Tissue
Expression Level
Larval Central Nervous System
305.925
Larval Midgut
446.5
Larval Hindgut
479.7
Larval Malpighian Tubules
1639.4
Larval Fat Body
936.7
Larval Salivary Gland
702
Larval Trachea
2176.25
Larval Carcass
453.2
Adult Head
647.5
Adult Eye
181.85
Adult Brain
1236.8
Adult Thoracic-Abdominal Ganglion
1143.8
Adult Crop
1835.9
Adult Midgut
365.9
Adult Hindgut
331.7
Adult Malpighian Tubules
1379.8
Adult Fat Body
119
Adult Salivary Gland
346.5
Adult Heart
272.275
Adult VirginFemale Spermatheca
223.1
Adult InseminatedFemale Spermatheca
266.2
Adult Ovary
476.6
Adult Testis
560.3
Adult Male Accessory Gland
1058.7
Adult Carcass
305.8
Expression Level Scale
Very high
log, scaled to maximum expression level
Tissue
Expression Level
Larval Central Nervous System
305.925
Larval Midgut
446.5
Larval Hindgut
479.7
Larval Malpighian Tubules
1639.4
Larval Fat Body
936.7
Larval Salivary Gland
702
Larval Trachea
2176.25
Larval Carcass
453.2
Adult Head
647.5
Adult Eye
181.85
Adult Brain
1236.8
Adult Thoracic-Abdominal Ganglion
1143.8
Adult Crop
1835.9
Adult Midgut
365.9
Adult Hindgut
331.7
Adult Malpighian Tubules
1379.8
Adult Fat Body
119
Adult Salivary Gland
346.5
Adult Heart
272.275
Adult VirginFemale Spermatheca
223.1
Adult InseminatedFemale Spermatheca
266.2
Adult Ovary
476.6
Adult Testis
560.3
Adult Male Accessory Gland
1058.7
Adult Carcass
305.8
Expression Level Scale
None
Low
Moderate
High
Very high
log, scaled to Moderate expression
Tissue
Expression Level
Larval Central Nervous System
305.925
Larval Midgut
446.5
Larval Hindgut
479.7
Larval Malpighian Tubules
(1639.4)
Larval Fat Body
(936.7)
Larval Salivary Gland
702
Larval Trachea
(2176.25)
Larval Carcass
453.2
Adult Head
647.5
Adult Eye
181.85
Adult Brain
(1236.8)
Adult Thoracic-Abdominal Ganglion
(1143.8)
Adult Crop
(1835.9)
Adult Midgut
365.9
Adult Hindgut
331.7
Adult Malpighian Tubules
(1379.8)
Adult Fat Body
119
Adult Salivary Gland
346.5
Adult Heart
272.275
Adult VirginFemale Spermatheca
223.1
Adult InseminatedFemale Spermatheca
266.2
Adult Ovary
476.6
Adult Testis
560.3
Adult Male Accessory Gland
(1058.7)
Adult Carcass
305.8
Expression Level Scale
None
Low
Moderate
High
log, scaled to High level expression
Tissue
Expression Level
Larval Central Nervous System
305.925
Larval Midgut
446.5
Larval Hindgut
479.7
Larval Malpighian Tubules
1639.4
Larval Fat Body
936.7
Larval Salivary Gland
702
Larval Trachea
(2176.25)
Larval Carcass
453.2
Adult Head
647.5
Adult Eye
181.85
Adult Brain
1236.8
Adult Thoracic-Abdominal Ganglion
1143.8
Adult Crop
(1835.9)
Adult Midgut
365.9
Adult Hindgut
331.7
Adult Malpighian Tubules
1379.8
Adult Fat Body
119
Adult Salivary Gland
346.5
Adult Heart
272.275
Adult VirginFemale Spermatheca
223.1
Adult InseminatedFemale Spermatheca
266.2
Adult Ovary
476.6
Adult Testis
560.3
Adult Male Accessory Gland
1058.7
Adult Carcass
305.8
Expression Level Scale
None
Low
Moderate
High
Very high
log, scaled to Very high expression
Tissue
Expression Level
Larval Central Nervous System
305.925
Larval Midgut
446.5
Larval Hindgut
479.7
Larval Malpighian Tubules
1639.4
Larval Fat Body
936.7
Larval Salivary Gland
702
Larval Trachea
2176.25
Larval Carcass
453.2
Adult Head
647.5
Adult Eye
181.85
Adult Brain
1236.8
Adult Thoracic-Abdominal Ganglion
1143.8
Adult Crop
1835.9
Adult Midgut
365.9
Adult Hindgut
331.7
Adult Malpighian Tubules
1379.8
Adult Fat Body
119
Adult Salivary Gland
346.5
Adult Heart
272.275
Adult VirginFemale Spermatheca
223.1
Adult InseminatedFemale Spermatheca
266.2
Adult Ovary
476.6
Adult Testis
560.3
Adult Male Accessory Gland
1058.7
Adult Carcass
305.8
Expression Level Scale
None
Low
Moderate
High
Very high
Heatmap
Tissue
Expression Level
Larval Central Nervous System
Larval Midgut
Larval Hindgut
Larval Malpighian Tubules
Larval Fat Body
Larval Salivary Gland
Larval Trachea
Larval Carcass
Adult Head
Adult Eye
Adult Brain
Adult Thoracic-Abdominal Ganglion
Adult Crop
Adult Midgut
Adult Hindgut
Adult Malpighian Tubules
Adult Fat Body
Adult Salivary Gland
Adult Heart
Adult VirginFemale Spermatheca
Adult InseminatedFemale Spermatheca
Adult Ovary
Adult Testis
Adult Male Accessory Gland
Adult Carcass
FlyAtlas Organ/Tissue Expression, larval vs. adult
Larval Expression Level
Tissue
Adult Expression Level
NA
Head
647.5
NA
Eye
181.85
NA
Brain
1236.8
305.925
Central Nervous System
NA
NA
Thoracic-Abdominal Ganglion
1143.8
NA
Crop
1835.9
446.5
Midgut
365.9
479.7
Hindgut
331.7
1639.4
Malpighian Tubules
1379.8
936.7
Fat Body
119
702
Salivary Gland
346.5
NA
Heart
272.275
2176.25
Trachea
NA
NA
VirginFemale Spermatheca
223.1
NA
InseminatedFemale Spermatheca
266.2
NA
Ovary
476.6
NA
Testis
560.3
NA
Male Accessory Gland
1058.7
453.2
Carcass
305.8
modENCODE Anatomy RNA-Seq
Linear, scaled to maximum expression level
Tissue
Expression Level
imaginal disc, larvae L3 wandering
23
central nervous system, larvae L3
13
central nervous system, pupae P8
28
head, virgin 1-day female
57
head, virgin 4-day female
46
head, virgin 20-day female
52
head, mated 1-day female
34
head, mated 4-day female
33
head, mated 20-day female
33
head, mated 1-day male
69
head, mated 4-day male
62
head, mated 20-day male
71
salivary gland, larvae L3 wandering
40
salivary gland, white prepupae
49
digestive system, larvae L3 wandering
41
digestive system, 1-day adult
30
digestive system, 4-day adult
22
digestive system, 20-day adult
25
fat body, larvae L3 wandering
12
fat body, white prepupae
31
fat body, pupae P8
70
carcass, larvae L3 wandering
23
carcass, 1-day adult
22
carcass, 4-day adult
19
carcass, 20-day adult
17
ovary, virgin 4-day female
47
ovary, mated 4-day female
32
testis, mated 4-day male
113
accessory gland, mated 4-day male
87
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Moderate expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
23
central nervous system, larvae L3
13
central nervous system, pupae P8
(28)
head, virgin 1-day female
(57)
head, virgin 4-day female
(46)
head, virgin 20-day female
(52)
head, mated 1-day female
(34)
head, mated 4-day female
(33)
head, mated 20-day female
(33)
head, mated 1-day male
(69)
head, mated 4-day male
(62)
head, mated 20-day male
(71)
salivary gland, larvae L3 wandering
(40)
salivary gland, white prepupae
(49)
digestive system, larvae L3 wandering
(41)
digestive system, 1-day adult
(30)
digestive system, 4-day adult
22
digestive system, 20-day adult
25
fat body, larvae L3 wandering
12
fat body, white prepupae
(31)
fat body, pupae P8
(70)
carcass, larvae L3 wandering
23
carcass, 1-day adult
22
carcass, 4-day adult
19
carcass, 20-day adult
17
ovary, virgin 4-day female
(47)
ovary, mated 4-day female
(32)
testis, mated 4-day male
(113)
accessory gland, mated 4-day male
(87)
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
23
central nervous system, larvae L3
13
central nervous system, pupae P8
28
head, virgin 1-day female
57
head, virgin 4-day female
46
head, virgin 20-day female
52
head, mated 1-day female
34
head, mated 4-day female
33
head, mated 20-day female
33
head, mated 1-day male
69
head, mated 4-day male
62
head, mated 20-day male
71
salivary gland, larvae L3 wandering
40
salivary gland, white prepupae
49
digestive system, larvae L3 wandering
41
digestive system, 1-day adult
30
digestive system, 4-day adult
22
digestive system, 20-day adult
25
fat body, larvae L3 wandering
12
fat body, white prepupae
31
fat body, pupae P8
70
carcass, larvae L3 wandering
23
carcass, 1-day adult
22
carcass, 4-day adult
19
carcass, 20-day adult
17
ovary, virgin 4-day female
47
ovary, mated 4-day female
32
testis, mated 4-day male
(113)
accessory gland, mated 4-day male
87
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
23
central nervous system, larvae L3
13
central nervous system, pupae P8
28
head, virgin 1-day female
57
head, virgin 4-day female
46
head, virgin 20-day female
52
head, mated 1-day female
34
head, mated 4-day female
33
head, mated 20-day female
33
head, mated 1-day male
69
head, mated 4-day male
62
head, mated 20-day male
71
salivary gland, larvae L3 wandering
40
salivary gland, white prepupae
49
digestive system, larvae L3 wandering
41
digestive system, 1-day adult
30
digestive system, 4-day adult
22
digestive system, 20-day adult
25
fat body, larvae L3 wandering
12
fat body, white prepupae
31
fat body, pupae P8
70
carcass, larvae L3 wandering
23
carcass, 1-day adult
22
carcass, 4-day adult
19
carcass, 20-day adult
17
ovary, virgin 4-day female
47
ovary, mated 4-day female
32
testis, mated 4-day male
113
accessory gland, mated 4-day male
87
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Tissue
Expression Level
imaginal disc, larvae L3 wandering
23
central nervous system, larvae L3
13
central nervous system, pupae P8
28
head, virgin 1-day female
57
head, virgin 4-day female
46
head, virgin 20-day female
52
head, mated 1-day female
34
head, mated 4-day female
33
head, mated 20-day female
33
head, mated 1-day male
69
head, mated 4-day male
62
head, mated 20-day male
71
salivary gland, larvae L3 wandering
40
salivary gland, white prepupae
49
digestive system, larvae L3 wandering
41
digestive system, 1-day adult
30
digestive system, 4-day adult
22
digestive system, 20-day adult
25
fat body, larvae L3 wandering
12
fat body, white prepupae
31
fat body, pupae P8
70
carcass, larvae L3 wandering
23
carcass, 1-day adult
22
carcass, 4-day adult
19
carcass, 20-day adult
17
ovary, virgin 4-day female
47
ovary, mated 4-day female
32
testis, mated 4-day male
113
accessory gland, mated 4-day male
87
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Moderate expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
23
central nervous system, larvae L3
13
central nervous system, pupae P8
28
head, virgin 1-day female
(57)
head, virgin 4-day female
(46)
head, virgin 20-day female
(52)
head, mated 1-day female
(34)
head, mated 4-day female
(33)
head, mated 20-day female
(33)
head, mated 1-day male
(69)
head, mated 4-day male
(62)
head, mated 20-day male
(71)
salivary gland, larvae L3 wandering
(40)
salivary gland, white prepupae
(49)
digestive system, larvae L3 wandering
(41)
digestive system, 1-day adult
30
digestive system, 4-day adult
22
digestive system, 20-day adult
25
fat body, larvae L3 wandering
12
fat body, white prepupae
31
fat body, pupae P8
(70)
carcass, larvae L3 wandering
23
carcass, 1-day adult
22
carcass, 4-day adult
19
carcass, 20-day adult
17
ovary, virgin 4-day female
(47)
ovary, mated 4-day female
32
testis, mated 4-day male
(113)
accessory gland, mated 4-day male
(87)
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
23
central nervous system, larvae L3
13
central nervous system, pupae P8
28
head, virgin 1-day female
57
head, virgin 4-day female
46
head, virgin 20-day female
52
head, mated 1-day female
34
head, mated 4-day female
33
head, mated 20-day female
33
head, mated 1-day male
69
head, mated 4-day male
62
head, mated 20-day male
71
salivary gland, larvae L3 wandering
40
salivary gland, white prepupae
49
digestive system, larvae L3 wandering
41
digestive system, 1-day adult
30
digestive system, 4-day adult
22
digestive system, 20-day adult
25
fat body, larvae L3 wandering
12
fat body, white prepupae
31
fat body, pupae P8
70
carcass, larvae L3 wandering
23
carcass, 1-day adult
22
carcass, 4-day adult
19
carcass, 20-day adult
17
ovary, virgin 4-day female
47
ovary, mated 4-day female
32
testis, mated 4-day male
113
accessory gland, mated 4-day male
87
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
23
central nervous system, larvae L3
13
central nervous system, pupae P8
28
head, virgin 1-day female
57
head, virgin 4-day female
46
head, virgin 20-day female
52
head, mated 1-day female
34
head, mated 4-day female
33
head, mated 20-day female
33
head, mated 1-day male
69
head, mated 4-day male
62
head, mated 20-day male
71
salivary gland, larvae L3 wandering
40
salivary gland, white prepupae
49
digestive system, larvae L3 wandering
41
digestive system, 1-day adult
30
digestive system, 4-day adult
22
digestive system, 20-day adult
25
fat body, larvae L3 wandering
12
fat body, white prepupae
31
fat body, pupae P8
70
carcass, larvae L3 wandering
23
carcass, 1-day adult
22
carcass, 4-day adult
19
carcass, 20-day adult
17
ovary, virgin 4-day female
47
ovary, mated 4-day female
32
testis, mated 4-day male
113
accessory gland, mated 4-day male
87
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Tissue
Expression Level
imaginal disc, larvae L3 wandering
central nervous system, larvae L3
central nervous system, pupae P8
head, virgin 1-day female
head, virgin 4-day female
head, virgin 20-day female
head, mated 1-day female
head, mated 4-day female
head, mated 20-day female
head, mated 1-day male
head, mated 4-day male
head, mated 20-day male
salivary gland, larvae L3 wandering
salivary gland, white prepupae
digestive system, larvae L3 wandering
digestive system, 1-day adult
digestive system, 4-day adult
digestive system, 20-day adult
fat body, larvae L3 wandering
fat body, white prepupae
fat body, pupae P8
carcass, larvae L3 wandering
carcass, 1-day adult
carcass, 4-day adult
carcass, 20-day adult
ovary, virgin 4-day female
ovary, mated 4-day female
testis, mated 4-day male
accessory gland, mated 4-day male
modENCODE Development RNA-Seq
Linear, scaled to maximum expression level
Developmental Stage
Expression Level
embryo 00-02hr
45
embryo 02-04hr
50
embryo 04-06hr
18
embryo 06-08hr
6
embryo 08-10hr
11
embryo 10-12hr
13
embryo 12-14hr
13
embryo 14-16hr
22
embryo 16-18hr
24
embryo 18-20hr
36
embryo 20-22hr
55
embryo 22-24hr
60
larva L1
31
larva L2
30
larva L3 12hr old
32
larva L3 puffstage 1-2
29
larva L3 puffstage 3-6
30
larva L3 puffstage 7-9
35
white prepupae new
31
white prepupae 12hr
50
white prepupae 24hr
43
pupae 2d postWPP
203
pupae 3d postWPP
71
pupae 4d postWPP
61
adult male 01day
52
adult male 05day
48
adult male 30day
46
adult female 01day
42
adult female 05day
30
adult female 30day
31
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Moderate expression
Developmental Stage
Expression Level
embryo 00-02hr
(45)
embryo 02-04hr
(50)
embryo 04-06hr
18
embryo 06-08hr
6
embryo 08-10hr
11
embryo 10-12hr
13
embryo 12-14hr
13
embryo 14-16hr
22
embryo 16-18hr
24
embryo 18-20hr
(36)
embryo 20-22hr
(55)
embryo 22-24hr
(60)
larva L1
(31)
larva L2
(30)
larva L3 12hr old
(32)
larva L3 puffstage 1-2
(29)
larva L3 puffstage 3-6
(30)
larva L3 puffstage 7-9
(35)
white prepupae new
(31)
white prepupae 12hr
(50)
white prepupae 24hr
(43)
pupae 2d postWPP
(203)
pupae 3d postWPP
(71)
pupae 4d postWPP
(61)
adult male 01day
(52)
adult male 05day
(48)
adult male 30day
(46)
adult female 01day
(42)
adult female 05day
(30)
adult female 30day
(31)
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Developmental Stage
Expression Level
embryo 00-02hr
45
embryo 02-04hr
50
embryo 04-06hr
18
embryo 06-08hr
6
embryo 08-10hr
11
embryo 10-12hr
13
embryo 12-14hr
13
embryo 14-16hr
22
embryo 16-18hr
24
embryo 18-20hr
36
embryo 20-22hr
55
embryo 22-24hr
60
larva L1
31
larva L2
30
larva L3 12hr old
32
larva L3 puffstage 1-2
29
larva L3 puffstage 3-6
30
larva L3 puffstage 7-9
35
white prepupae new
31
white prepupae 12hr
50
white prepupae 24hr
43
pupae 2d postWPP
(203)
pupae 3d postWPP
71
pupae 4d postWPP
61
adult male 01day
52
adult male 05day
48
adult male 30day
46
adult female 01day
42
adult female 05day
30
adult female 30day
31
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Developmental Stage
Expression Level
embryo 00-02hr
45
embryo 02-04hr
50
embryo 04-06hr
18
embryo 06-08hr
6
embryo 08-10hr
11
embryo 10-12hr
13
embryo 12-14hr
13
embryo 14-16hr
22
embryo 16-18hr
24
embryo 18-20hr
36
embryo 20-22hr
55
embryo 22-24hr
60
larva L1
31
larva L2
30
larva L3 12hr old
32
larva L3 puffstage 1-2
29
larva L3 puffstage 3-6
30
larva L3 puffstage 7-9
35
white prepupae new
31
white prepupae 12hr
50
white prepupae 24hr
43
pupae 2d postWPP
203
pupae 3d postWPP
71
pupae 4d postWPP
61
adult male 01day
52
adult male 05day
48
adult male 30day
46
adult female 01day
42
adult female 05day
30
adult female 30day
31
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Developmental Stage
Expression Level
embryo 00-02hr
45
embryo 02-04hr
50
embryo 04-06hr
18
embryo 06-08hr
6
embryo 08-10hr
11
embryo 10-12hr
13
embryo 12-14hr
13
embryo 14-16hr
22
embryo 16-18hr
24
embryo 18-20hr
36
embryo 20-22hr
55
embryo 22-24hr
60
larva L1
31
larva L2
30
larva L3 12hr old
32
larva L3 puffstage 1-2
29
larva L3 puffstage 3-6
30
larva L3 puffstage 7-9
35
white prepupae new
31
white prepupae 12hr
50
white prepupae 24hr
43
pupae 2d postWPP
203
pupae 3d postWPP
71
pupae 4d postWPP
61
adult male 01day
52
adult male 05day
48
adult male 30day
46
adult female 01day
42
adult female 05day
30
adult female 30day
31
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Moderate expression
Developmental Stage
Expression Level
embryo 00-02hr
(45)
embryo 02-04hr
(50)
embryo 04-06hr
18
embryo 06-08hr
6
embryo 08-10hr
11
embryo 10-12hr
13
embryo 12-14hr
13
embryo 14-16hr
22
embryo 16-18hr
24
embryo 18-20hr
(36)
embryo 20-22hr
(55)
embryo 22-24hr
(60)
larva L1
31
larva L2
30
larva L3 12hr old
32
larva L3 puffstage 1-2
29
larva L3 puffstage 3-6
30
larva L3 puffstage 7-9
(35)
white prepupae new
31
white prepupae 12hr
(50)
white prepupae 24hr
(43)
pupae 2d postWPP
(203)
pupae 3d postWPP
(71)
pupae 4d postWPP
(61)
adult male 01day
(52)
adult male 05day
(48)
adult male 30day
(46)
adult female 01day
(42)
adult female 05day
30
adult female 30day
31
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Developmental Stage
Expression Level
embryo 00-02hr
45
embryo 02-04hr
50
embryo 04-06hr
18
embryo 06-08hr
6
embryo 08-10hr
11
embryo 10-12hr
13
embryo 12-14hr
13
embryo 14-16hr
22
embryo 16-18hr
24
embryo 18-20hr
36
embryo 20-22hr
55
embryo 22-24hr
60
larva L1
31
larva L2
30
larva L3 12hr old
32
larva L3 puffstage 1-2
29
larva L3 puffstage 3-6
30
larva L3 puffstage 7-9
35
white prepupae new
31
white prepupae 12hr
50
white prepupae 24hr
43
pupae 2d postWPP
(203)
pupae 3d postWPP
71
pupae 4d postWPP
61
adult male 01day
52
adult male 05day
48
adult male 30day
46
adult female 01day
42
adult female 05day
30
adult female 30day
31
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Developmental Stage
Expression Level
embryo 00-02hr
45
embryo 02-04hr
50
embryo 04-06hr
18
embryo 06-08hr
6
embryo 08-10hr
11
embryo 10-12hr
13
embryo 12-14hr
13
embryo 14-16hr
22
embryo 16-18hr
24
embryo 18-20hr
36
embryo 20-22hr
55
embryo 22-24hr
60
larva L1
31
larva L2
30
larva L3 12hr old
32
larva L3 puffstage 1-2
29
larva L3 puffstage 3-6
30
larva L3 puffstage 7-9
35
white prepupae new
31
white prepupae 12hr
50
white prepupae 24hr
43
pupae 2d postWPP
203
pupae 3d postWPP
71
pupae 4d postWPP
61
adult male 01day
52
adult male 05day
48
adult male 30day
46
adult female 01day
42
adult female 05day
30
adult female 30day
31
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Developmental Stage
Expression Level
embryo 00-02hr
embryo 02-04hr
embryo 04-06hr
embryo 06-08hr
embryo 08-10hr
embryo 10-12hr
embryo 12-14hr
embryo 14-16hr
embryo 16-18hr
embryo 18-20hr
embryo 20-22hr
embryo 22-24hr
larva L1
larva L2
larva L3 12hr old
larva L3 puffstage 1-2
larva L3 puffstage 3-6
larva L3 puffstage 7-9
white prepupae new
white prepupae 12hr
white prepupae 24hr
pupae 2d postWPP
pupae 3d postWPP
pupae 4d postWPP
adult male 01day
adult male 05day
adult male 30day
adult female 01day
adult female 05day
adult female 30day
modENCODE Cell Lines RNA-Seq
Linear, scaled to maximum expression level
Cell Line
Expression Level
Schneider line 2 S2R+
206
Schneider line 2 Sg4
94
embryonic 1182-4H
67
embryonic GM2
110
embryonic Kc167
3
embryonic S1
85
embryonic S3
43
leg disc CME L1
65
wing disc CME-W2
91
wing disc ML-DmD8
37
wing disc ML-DmD9
62
wing disc ML-DmD16-c3
37
wing disc ML-DmD21
58
wing disc ML-DmD32
46
haltere disc ML-DmD17-c3
89
eye-antennal disc ML-DmD11
35
antennal disc ML-DmD20-c5
47
mixed discs ML-DmD4-c1
85
CNS ML-DmBG1-c1
26
CNS ML-DmBG2-c2
131
tumorous blood cells mbn2
127
ovary fGS/OSS
6
ovary OSC
22
ovary OSS
4
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Moderate expression
Cell Line
Expression Level
Schneider line 2 S2R+
(206)
Schneider line 2 Sg4
(94)
embryonic 1182-4H
(67)
embryonic GM2
(110)
embryonic Kc167
3
embryonic S1
(85)
embryonic S3
(43)
leg disc CME L1
(65)
wing disc CME-W2
(91)
wing disc ML-DmD8
(37)
wing disc ML-DmD9
(62)
wing disc ML-DmD16-c3
(37)
wing disc ML-DmD21
(58)
wing disc ML-DmD32
(46)
haltere disc ML-DmD17-c3
(89)
eye-antennal disc ML-DmD11
(35)
antennal disc ML-DmD20-c5
(47)
mixed discs ML-DmD4-c1
(85)
CNS ML-DmBG1-c1
26
CNS ML-DmBG2-c2
(131)
tumorous blood cells mbn2
(127)
ovary fGS/OSS
6
ovary OSC
22
ovary OSS
4
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Cell Line
Expression Level
Schneider line 2 S2R+
(206)
Schneider line 2 Sg4
94
embryonic 1182-4H
67
embryonic GM2
(110)
embryonic Kc167
3
embryonic S1
85
embryonic S3
43
leg disc CME L1
65
wing disc CME-W2
91
wing disc ML-DmD8
37
wing disc ML-DmD9
62
wing disc ML-DmD16-c3
37
wing disc ML-DmD21
58
wing disc ML-DmD32
46
haltere disc ML-DmD17-c3
89
eye-antennal disc ML-DmD11
35
antennal disc ML-DmD20-c5
47
mixed discs ML-DmD4-c1
85
CNS ML-DmBG1-c1
26
CNS ML-DmBG2-c2
(131)
tumorous blood cells mbn2
(127)
ovary fGS/OSS
6
ovary OSC
22
ovary OSS
4
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Cell Line
Expression Level
Schneider line 2 S2R+
206
Schneider line 2 Sg4
94
embryonic 1182-4H
67
embryonic GM2
110
embryonic Kc167
3
embryonic S1
85
embryonic S3
43
leg disc CME L1
65
wing disc CME-W2
91
wing disc ML-DmD8
37
wing disc ML-DmD9
62
wing disc ML-DmD16-c3
37
wing disc ML-DmD21
58
wing disc ML-DmD32
46
haltere disc ML-DmD17-c3
89
eye-antennal disc ML-DmD11
35
antennal disc ML-DmD20-c5
47
mixed discs ML-DmD4-c1
85
CNS ML-DmBG1-c1
26
CNS ML-DmBG2-c2
131
tumorous blood cells mbn2
127
ovary fGS/OSS
6
ovary OSC
22
ovary OSS
4
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Cell Line
Expression Level
Schneider line 2 S2R+
206
Schneider line 2 Sg4
94
embryonic 1182-4H
67
embryonic GM2
110
embryonic Kc167
3
embryonic S1
85
embryonic S3
43
leg disc CME L1
65
wing disc CME-W2
91
wing disc ML-DmD8
37
wing disc ML-DmD9
62
wing disc ML-DmD16-c3
37
wing disc ML-DmD21
58
wing disc ML-DmD32
46
haltere disc ML-DmD17-c3
89
eye-antennal disc ML-DmD11
35
antennal disc ML-DmD20-c5
47
mixed discs ML-DmD4-c1
85
CNS ML-DmBG1-c1
26
CNS ML-DmBG2-c2
131
tumorous blood cells mbn2
127
ovary fGS/OSS
6
ovary OSC
22
ovary OSS
4
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Moderate expression
Cell Line
Expression Level
Schneider line 2 S2R+
(206)
Schneider line 2 Sg4
(94)
embryonic 1182-4H
(67)
embryonic GM2
(110)
embryonic Kc167
3
embryonic S1
(85)
embryonic S3
(43)
leg disc CME L1
(65)
wing disc CME-W2
(91)
wing disc ML-DmD8
(37)
wing disc ML-DmD9
(62)
wing disc ML-DmD16-c3
(37)
wing disc ML-DmD21
(58)
wing disc ML-DmD32
(46)
haltere disc ML-DmD17-c3
(89)
eye-antennal disc ML-DmD11
(35)
antennal disc ML-DmD20-c5
(47)
mixed discs ML-DmD4-c1
(85)
CNS ML-DmBG1-c1
26
CNS ML-DmBG2-c2
(131)
tumorous blood cells mbn2
(127)
ovary fGS/OSS
6
ovary OSC
22
ovary OSS
4
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Cell Line
Expression Level
Schneider line 2 S2R+
(206)
Schneider line 2 Sg4
94
embryonic 1182-4H
67
embryonic GM2
110
embryonic Kc167
3
embryonic S1
85
embryonic S3
43
leg disc CME L1
65
wing disc CME-W2
91
wing disc ML-DmD8
37
wing disc ML-DmD9
62
wing disc ML-DmD16-c3
37
wing disc ML-DmD21
58
wing disc ML-DmD32
46
haltere disc ML-DmD17-c3
89
eye-antennal disc ML-DmD11
35
antennal disc ML-DmD20-c5
47
mixed discs ML-DmD4-c1
85
CNS ML-DmBG1-c1
26
CNS ML-DmBG2-c2
131
tumorous blood cells mbn2
127
ovary fGS/OSS
6
ovary OSC
22
ovary OSS
4
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Cell Line
Expression Level
Schneider line 2 S2R+
206
Schneider line 2 Sg4
94
embryonic 1182-4H
67
embryonic GM2
110
embryonic Kc167
3
embryonic S1
85
embryonic S3
43
leg disc CME L1
65
wing disc CME-W2
91
wing disc ML-DmD8
37
wing disc ML-DmD9
62
wing disc ML-DmD16-c3
37
wing disc ML-DmD21
58
wing disc ML-DmD32
46
haltere disc ML-DmD17-c3
89
eye-antennal disc ML-DmD11
35
antennal disc ML-DmD20-c5
47
mixed discs ML-DmD4-c1
85
CNS ML-DmBG1-c1
26
CNS ML-DmBG2-c2
131
tumorous blood cells mbn2
127
ovary fGS/OSS
6
ovary OSC
22
ovary OSS
4
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Cell Line
Expression Level
Schneider line 2 S2R+
Schneider line 2 Sg4
embryonic 1182-4H
embryonic GM2
embryonic Kc167
embryonic S1
embryonic S3
leg disc CME L1
wing disc CME-W2
wing disc ML-DmD8
wing disc ML-DmD9
wing disc ML-DmD16-c3
wing disc ML-DmD21
wing disc ML-DmD32
haltere disc ML-DmD17-c3
eye-antennal disc ML-DmD11
antennal disc ML-DmD20-c5
mixed discs ML-DmD4-c1
CNS ML-DmBG1-c1
CNS ML-DmBG2-c2
tumorous blood cells mbn2
ovary fGS/OSS
ovary OSC
ovary OSS
modENCODE Treatments RNA-Seq
Linear, scaled to maximum expression level
Treatment
Expression Level
extended cold, 4-day adult
13
cold shock, 4-day adult
11
heat shock, 4-day adult
28
Cadmium 50 mM 6 hrs, larvae L3
45
Cadmium 50 mM 12 hrs, larvae L3
44
Cadmium 50 mM 48 hrs, 4-day adult
28
Cadmium 100 mM 48 hrs, 4-day adult
29
Copper 0.5 mM 12 hrs, larvae L3
17
Copper 15 mM 48 hrs, 4-day adult
19
Zinc 5 mM 12 hrs, larvae L3
15
Zinc 4.5 mM 48 hrs, 4-day adult
16
Ethanol 2.5% 3 hrs, larvae L3
34
Ethanol 5% 3 hrs, larvae L3
45
Ethanol 10% 3 hrs, larvae L3
30
Caffeine 1.5 mg/ml 4 hrs, larvae L3
41
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
32
Caffeine 25 mg/ml 48 hrs, 4-day adult
12
Paraquat 5 mM 48 hrs, 4-day adult
43
Paraquat 10 mM 48 hrs, 4-day adult
40
Rotenone 2 μg 12 hrs, larvae L3
41
Rotenone 8 μg 12 hrs, larvae L3
34
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to Moderate expression
Treatment
Expression Level
extended cold, 4-day adult
13
cold shock, 4-day adult
11
heat shock, 4-day adult
(28)
Cadmium 50 mM 6 hrs, larvae L3
(45)
Cadmium 50 mM 12 hrs, larvae L3
(44)
Cadmium 50 mM 48 hrs, 4-day adult
(28)
Cadmium 100 mM 48 hrs, 4-day adult
(29)
Copper 0.5 mM 12 hrs, larvae L3
17
Copper 15 mM 48 hrs, 4-day adult
19
Zinc 5 mM 12 hrs, larvae L3
15
Zinc 4.5 mM 48 hrs, 4-day adult
16
Ethanol 2.5% 3 hrs, larvae L3
(34)
Ethanol 5% 3 hrs, larvae L3
(45)
Ethanol 10% 3 hrs, larvae L3
(30)
Caffeine 1.5 mg/ml 4 hrs, larvae L3
(41)
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
(32)
Caffeine 25 mg/ml 48 hrs, 4-day adult
12
Paraquat 5 mM 48 hrs, 4-day adult
(43)
Paraquat 10 mM 48 hrs, 4-day adult
(40)
Rotenone 2 μg 12 hrs, larvae L3
(41)
Rotenone 8 μg 12 hrs, larvae L3
(34)
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Treatment
Expression Level
extended cold, 4-day adult
13
cold shock, 4-day adult
11
heat shock, 4-day adult
28
Cadmium 50 mM 6 hrs, larvae L3
45
Cadmium 50 mM 12 hrs, larvae L3
44
Cadmium 50 mM 48 hrs, 4-day adult
28
Cadmium 100 mM 48 hrs, 4-day adult
29
Copper 0.5 mM 12 hrs, larvae L3
17
Copper 15 mM 48 hrs, 4-day adult
19
Zinc 5 mM 12 hrs, larvae L3
15
Zinc 4.5 mM 48 hrs, 4-day adult
16
Ethanol 2.5% 3 hrs, larvae L3
34
Ethanol 5% 3 hrs, larvae L3
45
Ethanol 10% 3 hrs, larvae L3
30
Caffeine 1.5 mg/ml 4 hrs, larvae L3
41
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
32
Caffeine 25 mg/ml 48 hrs, 4-day adult
12
Paraquat 5 mM 48 hrs, 4-day adult
43
Paraquat 10 mM 48 hrs, 4-day adult
40
Rotenone 2 μg 12 hrs, larvae L3
41
Rotenone 8 μg 12 hrs, larvae L3
34
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Treatment
Expression Level
extended cold, 4-day adult
13
cold shock, 4-day adult
11
heat shock, 4-day adult
28
Cadmium 50 mM 6 hrs, larvae L3
45
Cadmium 50 mM 12 hrs, larvae L3
44
Cadmium 50 mM 48 hrs, 4-day adult
28
Cadmium 100 mM 48 hrs, 4-day adult
29
Copper 0.5 mM 12 hrs, larvae L3
17
Copper 15 mM 48 hrs, 4-day adult
19
Zinc 5 mM 12 hrs, larvae L3
15
Zinc 4.5 mM 48 hrs, 4-day adult
16
Ethanol 2.5% 3 hrs, larvae L3
34
Ethanol 5% 3 hrs, larvae L3
45
Ethanol 10% 3 hrs, larvae L3
30
Caffeine 1.5 mg/ml 4 hrs, larvae L3
41
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
32
Caffeine 25 mg/ml 48 hrs, 4-day adult
12
Paraquat 5 mM 48 hrs, 4-day adult
43
Paraquat 10 mM 48 hrs, 4-day adult
40
Rotenone 2 μg 12 hrs, larvae L3
41
Rotenone 8 μg 12 hrs, larvae L3
34
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Treatment
Expression Level
extended cold, 4-day adult
13
cold shock, 4-day adult
11
heat shock, 4-day adult
28
Cadmium 50 mM 6 hrs, larvae L3
45
Cadmium 50 mM 12 hrs, larvae L3
44
Cadmium 50 mM 48 hrs, 4-day adult
28
Cadmium 100 mM 48 hrs, 4-day adult
29
Copper 0.5 mM 12 hrs, larvae L3
17
Copper 15 mM 48 hrs, 4-day adult
19
Zinc 5 mM 12 hrs, larvae L3
15
Zinc 4.5 mM 48 hrs, 4-day adult
16
Ethanol 2.5% 3 hrs, larvae L3
34
Ethanol 5% 3 hrs, larvae L3
45
Ethanol 10% 3 hrs, larvae L3
30
Caffeine 1.5 mg/ml 4 hrs, larvae L3
41
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
32
Caffeine 25 mg/ml 48 hrs, 4-day adult
12
Paraquat 5 mM 48 hrs, 4-day adult
43
Paraquat 10 mM 48 hrs, 4-day adult
40
Rotenone 2 μg 12 hrs, larvae L3
41
Rotenone 8 μg 12 hrs, larvae L3
34
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
log, scaled to Moderate expression
Treatment
Expression Level
extended cold, 4-day adult
13
cold shock, 4-day adult
11
heat shock, 4-day adult
28
Cadmium 50 mM 6 hrs, larvae L3
(45)
Cadmium 50 mM 12 hrs, larvae L3
(44)
Cadmium 50 mM 48 hrs, 4-day adult
28
Cadmium 100 mM 48 hrs, 4-day adult
29
Copper 0.5 mM 12 hrs, larvae L3
17
Copper 15 mM 48 hrs, 4-day adult
19
Zinc 5 mM 12 hrs, larvae L3
15
Zinc 4.5 mM 48 hrs, 4-day adult
16
Ethanol 2.5% 3 hrs, larvae L3
(34)
Ethanol 5% 3 hrs, larvae L3
(45)
Ethanol 10% 3 hrs, larvae L3
30
Caffeine 1.5 mg/ml 4 hrs, larvae L3
(41)
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
32
Caffeine 25 mg/ml 48 hrs, 4-day adult
12
Paraquat 5 mM 48 hrs, 4-day adult
(43)
Paraquat 10 mM 48 hrs, 4-day adult
(40)
Rotenone 2 μg 12 hrs, larvae L3
(41)
Rotenone 8 μg 12 hrs, larvae L3
(34)
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Treatment
Expression Level
extended cold, 4-day adult
13
cold shock, 4-day adult
11
heat shock, 4-day adult
28
Cadmium 50 mM 6 hrs, larvae L3
45
Cadmium 50 mM 12 hrs, larvae L3
44
Cadmium 50 mM 48 hrs, 4-day adult
28
Cadmium 100 mM 48 hrs, 4-day adult
29
Copper 0.5 mM 12 hrs, larvae L3
17
Copper 15 mM 48 hrs, 4-day adult
19
Zinc 5 mM 12 hrs, larvae L3
15
Zinc 4.5 mM 48 hrs, 4-day adult
16
Ethanol 2.5% 3 hrs, larvae L3
34
Ethanol 5% 3 hrs, larvae L3
45
Ethanol 10% 3 hrs, larvae L3
30
Caffeine 1.5 mg/ml 4 hrs, larvae L3
41
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
32
Caffeine 25 mg/ml 48 hrs, 4-day adult
12
Paraquat 5 mM 48 hrs, 4-day adult
43
Paraquat 10 mM 48 hrs, 4-day adult
40
Rotenone 2 μg 12 hrs, larvae L3
41
Rotenone 8 μg 12 hrs, larvae L3
34
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Treatment
Expression Level
extended cold, 4-day adult
13
cold shock, 4-day adult
11
heat shock, 4-day adult
28
Cadmium 50 mM 6 hrs, larvae L3
45
Cadmium 50 mM 12 hrs, larvae L3
44
Cadmium 50 mM 48 hrs, 4-day adult
28
Cadmium 100 mM 48 hrs, 4-day adult
29
Copper 0.5 mM 12 hrs, larvae L3
17
Copper 15 mM 48 hrs, 4-day adult
19
Zinc 5 mM 12 hrs, larvae L3
15
Zinc 4.5 mM 48 hrs, 4-day adult
16
Ethanol 2.5% 3 hrs, larvae L3
34
Ethanol 5% 3 hrs, larvae L3
45
Ethanol 10% 3 hrs, larvae L3
30
Caffeine 1.5 mg/ml 4 hrs, larvae L3
41
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
32
Caffeine 25 mg/ml 48 hrs, 4-day adult
12
Paraquat 5 mM 48 hrs, 4-day adult
43
Paraquat 10 mM 48 hrs, 4-day adult
40
Rotenone 2 μg 12 hrs, larvae L3
41
Rotenone 8 μg 12 hrs, larvae L3
34
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Treatment
Expression Level
extended cold, 4-day adult
cold shock, 4-day adult
heat shock, 4-day adult
Cadmium 50 mM 6 hrs, larvae L3
Cadmium 50 mM 12 hrs, larvae L3
Cadmium 50 mM 48 hrs, 4-day adult
Cadmium 100 mM 48 hrs, 4-day adult
Copper 0.5 mM 12 hrs, larvae L3
Copper 15 mM 48 hrs, 4-day adult
Zinc 5 mM 12 hrs, larvae L3
Zinc 4.5 mM 48 hrs, 4-day adult
Ethanol 2.5% 3 hrs, larvae L3
Ethanol 5% 3 hrs, larvae L3
Ethanol 10% 3 hrs, larvae L3
Caffeine 1.5 mg/ml 4 hrs, larvae L3
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
Caffeine 25 mg/ml 48 hrs, 4-day adult
Paraquat 5 mM 48 hrs, 4-day adult
Paraquat 10 mM 48 hrs, 4-day adult
Rotenone 2 μg 12 hrs, larvae L3
Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
A cluster of genes with similar mRNA expression dynamics across development.
External Data & Images
Linkouts
- Cell culture data for RNAi and other high-throughput technologies
- Adult expression by tissue, using Affymetrix Dros2 array
Alleles & Phenotypes Summary of Allele Phenotypes Classical Alleles ( 13 ) For All Classical Alleles Show Alleles Carried on Transgenic Constructs
( 2 ) For All Alleles Carried on Transgenic
Constructs Show Aneuploid Aberrations Transgenic Constructs & Insertions
Transgenic Constructs Insertions insertion of mobile activating element
Gene Ontology: Function, Process
& Cellular Component ( 3 unique terms ) Terms Based on
Experimental Evidence ( 0 terms ) Terms Based on Predictions or
Assertions ( 3 terms ) Molecular Function Biological Process ( 0 terms) Cellular Component Sequence Ontology: Class of Gene Interactions & Pathways
Summary of Physical Interactions
Summary of Genetic Interactions Interacts with Please look at the allele data
for full details of the genetic interactions
External Data Linkouts
- A database of protein and genetic interactions
- A comprehensive database of gene and protein interactions.
Protein-protein interactions (PPI) from both known and predicted PPI data sets.
Orthologs
OrthoDB Orthologs (57)
- based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
OrthoDB orthology group searches
Drosophila inclusive ortholog search
Dipteran inclusive ortholog search
Insect inclusive ortholog search
Arthropod inclusive ortholog search
Metazoa inclusive ortholog search
Orthologs in Drosophila Species
(EOG6N3185 )
Drosophila melanogaster
fruit fly
Drosophila pseudoobscura pseudoobscura
Y
Orthologs in non-Drosophila Dipterans
(EOG68KRM6 )
Aedes aegypti
Yellow fever mosquito
Anopheles gambiae
Malaria mosquito
Culex quinquefasciatus
Southern house mosquito
Culex quinquefasciatus
Southern house mosquito
Orthologs in non-Dipteran Insects
(EOG60RZBV )
Apis mellifera
Western honey bee
Amel\GB47538
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG006755
Acromyrmex echinatior
Panamanian leafcutter ant
Aech\AECH10376
Atta cephalotes
Leafcutter ant
Acep\ACEP10487
Camponotus floridanus
Florida carpenter ant
Cflo\CFLO16836
Harpegnathos saltator
Jerdons jumping ant
Hsal\HSAL12963
Linepithema humile
Argentine ant
Lhum\LH22207
Pogonomyrmex barbatus
Red harvester ant
Pbar\PB11131
Solenopsis invicta
Red fire ant
Sinv\SINV19423
Acyrthosiphon pisum
Pea aphid
Acyrthosiphon pisum
Pea aphid
Acyrthosiphon pisum
Pea aphid
Acyrthosiphon pisum
Pea aphid
Acyrthosiphon pisum
Pea aphid
Pediculus humanus
Human body louse
Tribolium castaneum
Red flour beetle
Orthologs in non-Insect Arthropods
(EOG60P2PX )
Ixodes scapularis
Deer tick
Orthologs in non-Arthropod Metazoa
(EOG6F28XP )
Caenorhabditis elegans
Nematode
Y
Caenorhabditis elegans
Nematode
Y
Caenorhabditis elegans
Nematode
Y
Strongylocentrotus purpuratus
Purple sea urchin
Y
Strongylocentrotus purpuratus
Purple sea urchin
Y
Strongylocentrotus purpuratus
Purple sea urchin
Y
Xenopus tropicalis
Western clawed frog
Y
Xenopus tropicalis
Western clawed frog
Y
Gallus gallus
Domestic chicken
Y
Gallus gallus
Domestic chicken
Y
Gallus gallus
Domestic chicken
Y
Mus musculus
House mouse
Y
Mus musculus
House mouse
Y
Mus musculus
House mouse
Y
Rattus norvegicus
Norway rat
Y
Rattus norvegicus
Norway rat
Y
Rattus norvegicus
Norway rat
Y
Human Orthologs (2)AAA Orthologs (11)
based on analysis using Dmel annotation version 4.3
Drosophila pseudoobscura pseudoobscura
Stocks & Reagents Stocks Listed in FlyBase ( 10 )Bloomington Harvard VDRC Genomic Clones ( 1 )Please Note FlyBase no
longer curates genomic clone accessions so this list
may not be complete
cDNA Clones ( 112 )Please Note This section lists
cDNAs and ESTs that fall within the genomic extent
of the gene model, which may include cDNAs and ESTs
of genes within introns, or of overlapping genes.
Please see
GBrowse for alignment of the cDNAs and ESTs
to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones Other clones cDNA Clones, End Sequenced
(ESTs) BDGP DGC clones Other clones RNAi & Array Information Linkouts
- Results from RNAi screens.
- GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents
Antibody Information
Other Information Discoverer Etymology Identification Relationship to Other Genes Source for database identity of Source for database merge of Source for merge of: CG1275 anon-WO0118547.260
Additional comments Source for merge of CG1275 anon-WO0118547.260 was sequence comparison (date:041213).
Other Comments Area matching Drosophila EST AA392916 (inverted).
External Crossreferences & Linkouts
Sequence Crossreferences
- A searchable database of RefSeq genes.
Other Crossreferences
domains - A database of protein families, domains, and functional sites
- Patterns of gene expression in Drosophila embryogenesis
Linkouts
- A database of protein and genetic interactions
- A comprehensive database of gene and protein interactions.
- Results from RNAi screens.
- Cell culture data for RNAi and other high-throughput technologies
- Adult expression by tissue, using Affymetrix Dros2 array
- Integrated genomics database for Drosophila, Anopheles, and C.elegans
- GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents
Protein-protein interactions (PPI) from both known and predicted PPI data sets.
- Data generated by the modENCODE project.
Synonyms & Secondary IDs
( 4 )Reported As Symbol Synonym Name Synonym Secondary FlyBase
IDs References ( 25 )Generate a list of List References by type
Recent research papers ( 2 )
Malone et al., 2012, Genome Biol. 13(4): r28Mediation of Drosophila autosomal dosage effects and compensation by network interactions. [FBrf0219684] Park et al., 2011, Curr. Biol. 21(18): 1515--1524Molecular organization of Drosophila neuroendocrine cells by dimmed. [FBrf0216231]