gene_with_dicistronic_mRNA ; SO:0000722
Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 5.46
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\MEP-1 using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\MEP-1 in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for identity of: MEP-1 CG1244
One or more of the processed transcripts for these genes contain two non-overlapping open reading frames (ORFs). The non-overlapping ORFs are represented by CG42245 (FBgn0250911), CG1244 (FBgn0035357).
Source for merge of CG1244 anon- EST:Liang-1.37 was sequence comparison ( date:030722 ).
Source for merge of CG1244 anon-WO0118547.584 was sequence comparison ( date:051113 ).
DNA-protein interactions: genome-wide binding profile assayed for MEP-1 protein in S2 cells; GEO accession number GSE32404.
dsRNA has been made from templates generated with primers directed against this gene. RNAi of CG1244 disrupts the dendritic routing patterns of the ddaD and ddaE neurons, resulting in aberrantly oriented primary dendrites. The overall arborization of these neurons is reduced. Additionally, RNAi causes defects in dendrite morphogenesis.