• Home
• Tools
  • Tools Overview
  • Query Tools

    
    • QuickSearch
    • QueryBuilder
    • TermLink
    • CytoSearch
    • Interactions Browser
    • ImageBrowse
    • Find A Person
    • Google™ FlyBase
  • Genomic/Map Tools

    
    • BLAST
    • GBrowse
    • CytoSearch
    • Aberrations Maps
    • Chromosome Maps
    • Coordinates Converter
  • Retrieve/Convert

    
    • Batch Download
    • Coordinates Converter
    • ID Converter
  • Data Submission

    
    • Fast-Track Your Paper
    • Submit Personal Comm
    • Add A New Person
    • Update Person Info
  • People

    
    • Find A Person
    • Add A New Person
    • Update Person Info
• Files
  • Files Overview
  • Downloads:
  • Precomputed files
  • Archived data
  • Releases (FTP)
  • Genomes (FTP)
  • AAA data (FTP)
  • Lists:
  • Transposons (Dmel)
  • Transposons (other)
  • Vectors & Constructs
  • Anatomical Terms
  • Map Conversion
• Species
  • Phylogeny
  • Sequenced Species
  • Synteny Table
  • Color Illustrations
  • Abbreviations
• Documents
  • About FlyBase
  • Reference Manual:
  • Sections
  • Contents
  • Nomenclature
  • Release Notes
• Resources
  • All Resources
  • Model Organisms
  • Stock Collections
  • Other links:
  • BDGP
  • DGRC
  • FlyExpress
  • Interactive Fly
  • modENCODE
  • Textpresso for Fly
• News
  • News
  • FlyBase Forum
  • FlyBase Positions
  • Meetings
  • Courses
  • Fly Board
  • White papers
  • Funding
  • bionet.dros
• Help
  • Google™ FlyBase
  • Site Map
  • FAQs
  • FlyBase Guides
  • Video Tutorials
  • Report help
  • New to Flies
  • Pers. comm.
  • Author guidelines
  • Contact FlyBase
• Archives
  • Prior Release
  • Other Archives
  • Coordinate Converter

Gene Dmel\CG11526

General Information
Symbol	Dmel\CG11526	Species	D. melanogaster
Name		Annotation symbol	CG11526
Feature type	protein_coding_gene	FlyBase ID	FBgn0035437
Gene Model Status	Current	Stock availability	8 publicly available
Genomic Location
Chromosome (arm)	3L	Recombination map
Cytogenetic map	63D1-63D1	Sequence location	3L:3,322,484..3,328,871 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG11526 (FBgn0035437). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 7 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: N1221-like; Protein of unknown function DUF3402. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed at stages throughout embryogenesis, during late larval stages, at stages throughout the pupal period, in stages of adults of both sexes. Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult testis. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male accessory gland, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1632794_a_at partially aligns to an exonic region common to each of the 2 FlyBase-annotated transcript isoforms of CG11526: 12 out of 14 probes fall into this exonic region. Gene sequence location is 3L:3322484..3328871.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2011_10
FB2012_01	Sequence features HFA08194 BKN22135
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 63D1-63D1   Limits computationally determined from genome sequence between P{PZ}l(3)0680306803 and P{PZ}kst01318
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG11526 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG11526-RA FBtr0073083  NM_168023   3596   882 CG11526-RB FBtr0073084  NM_139549   3161   927
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG11526-PA   FBpp0072945   99.7   882   5.09     NP_728867   AAF47760 CG11526-PB   FBpp0072946   104.7   927   5.61     NP_647806   AAN11560
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • N1221-like (IPR012486) Protein of unknown function DUF3402 (IPR021819)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA201554   AE014296 AAF47760   AE014296 AAN11560   AI530935   AI533904   AW944441   BE975156   BF486331   BF487041   BF487158   BF489275   BF491079   BF491824   BF492090   BF492259   BF494361   BF496384   BF497314   BF497636   BF498664   BF500609   BF501125   BF502638   BF502928   BF504422   BF505580   BG634459   BI169805   BI170381   BI171219   BI238494   BI241760   BI355955   BI358389   BI366189   BI366434   BI369939   BI372473   BI483261   BI483701   BI483750   BI483897   BI484972   BI568092   BI568345   BI573745   BI575816   BI576671   BI576845   BI576954   BI578057   BI580832   BI585738   BI585850   BI611533   BI612704   BI613647   BI634199   BI634412   BT003798   BT024459   CA804388   CA807430   CK605388   CK605389   CK660577   CK660702   CO187432   CO190605   CO268419   CO275747   CO277010   CO286701   CO288869   CO293820   CO303065   CO311987   CO319360   CO328732   CO333739   CO342743   CO343003   CO345528   CZ482245   EC065596   EC066752   EC069101   EC072541   EC076417   EC090089   EC090789   EC206971   EC206972   EC208839   EC212651   EC217738   EC227272   EC232217   EC245780   EC256120   EC259491   EC259774   ES695765
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q8IRD5 Q9VZQ9
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0035437    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0035437 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed at stages throughout embryogenesis, during late larval stages, at stages throughout the pupal period, in stages of adults of both sexes. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0035437 expression level Developmental Stage   Expression Level embryo 00-02hr    3850 embryo 02-04hr    2943 embryo 04-06hr    2761 embryo 06-08hr    2653 embryo 08-10hr    2373 embryo 10-12hr    2138 embryo 12-14hr    1755 embryo 14-16hr    2032 embryo 16-18hr    1536 embryo 18-20hr    1416 embryo 20-22hr    1221 embryo 22-24hr    1250 larva L1    1252 larva L2    916 larva L3 12hr old    801 larva L3 puffstage 1-2    1105 larva L3 puffstage 3-6    1982 larva L3 puffstage 7-9    2299 white prepupae new    2599 white prepupae 12hr    3119 white prepupae 24hr    3706 pupae 2d postWPP    3112 pupae 3d postWPP    2095 pupae 4d postWPP    2212 adult male 01day    2972 adult male 05day    3937 adult male 30day    3884 adult female 01day    1773 adult female 05day    2218 adult female 30day    2250 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (3850) embryo 02-04hr  (2943) embryo 04-06hr  (2761) embryo 06-08hr  (2653) embryo 08-10hr  (2373) embryo 10-12hr  (2138) embryo 12-14hr  (1755) embryo 14-16hr  (2032) embryo 16-18hr  (1536) embryo 18-20hr  (1416) embryo 20-22hr  (1221) embryo 22-24hr  (1250) larva L1  (1252) larva L2  (916) larva L3 12hr old  (801) larva L3 puffstage 1-2  (1105) larva L3 puffstage 3-6  (1982) larva L3 puffstage 7-9  (2299) white prepupae new  (2599) white prepupae 12hr  (3119) white prepupae 24hr  (3706) pupae 2d postWPP  (3112) pupae 3d postWPP  (2095) pupae 4d postWPP  (2212) adult male 01day  (2972) adult male 05day  (3937) adult male 30day  (3884) adult female 01day  (1773) adult female 05day  (2218) adult female 30day  (2250) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (3850) embryo 02-04hr  (2943) embryo 04-06hr  (2761) embryo 06-08hr  (2653) embryo 08-10hr  (2373) embryo 10-12hr  (2138) embryo 12-14hr  (1755) embryo 14-16hr  (2032) embryo 16-18hr  (1536) embryo 18-20hr  1416 embryo 20-22hr    1221 embryo 22-24hr    1250 larva L1    1252 larva L2    916 larva L3 12hr old    801 larva L3 puffstage 1-2    1105 larva L3 puffstage 3-6  (1982) larva L3 puffstage 7-9  (2299) white prepupae new  (2599) white prepupae 12hr  (3119) white prepupae 24hr  (3706) pupae 2d postWPP  (3112) pupae 3d postWPP  (2095) pupae 4d postWPP  (2212) adult male 01day  (2972) adult male 05day  (3937) adult male 30day  (3884) adult female 01day  (1773) adult female 05day  (2218) adult female 30day  (2250) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    3850 embryo 02-04hr    2943 embryo 04-06hr    2761 embryo 06-08hr    2653 embryo 08-10hr    2373 embryo 10-12hr    2138 embryo 12-14hr    1755 embryo 14-16hr    2032 embryo 16-18hr    1536 embryo 18-20hr    1416 embryo 20-22hr    1221 embryo 22-24hr    1250 larva L1    1252 larva L2    916 larva L3 12hr old    801 larva L3 puffstage 1-2    1105 larva L3 puffstage 3-6    1982 larva L3 puffstage 7-9    2299 white prepupae new    2599 white prepupae 12hr    3119 white prepupae 24hr    3706 pupae 2d postWPP    3112 pupae 3d postWPP    2095 pupae 4d postWPP    2212 adult male 01day    2972 adult male 05day    3937 adult male 30day    3884 adult female 01day    1773 adult female 05day    2218 adult female 30day    2250 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    3850 embryo 02-04hr    2943 embryo 04-06hr    2761 embryo 06-08hr    2653 embryo 08-10hr    2373 embryo 10-12hr    2138 embryo 12-14hr    1755 embryo 14-16hr    2032 embryo 16-18hr    1536 embryo 18-20hr    1416 embryo 20-22hr    1221 embryo 22-24hr    1250 larva L1    1252 larva L2    916 larva L3 12hr old    801 larva L3 puffstage 1-2    1105 larva L3 puffstage 3-6    1982 larva L3 puffstage 7-9    2299 white prepupae new    2599 white prepupae 12hr    3119 white prepupae 24hr    3706 pupae 2d postWPP    3112 pupae 3d postWPP    2095 pupae 4d postWPP    2212 adult male 01day    2972 adult male 05day    3937 adult male 30day    3884 adult female 01day    1773 adult female 05day    2218 adult female 30day    2250 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0035437 expression level Developmental Stage   Expression Level embryo 00-02hr    3850 embryo 02-04hr    2943 embryo 04-06hr    2761 embryo 06-08hr    2653 embryo 08-10hr    2373 embryo 10-12hr    2138 embryo 12-14hr    1755 embryo 14-16hr    2032 embryo 16-18hr    1536 embryo 18-20hr    1416 embryo 20-22hr    1221 embryo 22-24hr    1250 larva L1    1252 larva L2    916 larva L3 12hr old    801 larva L3 puffstage 1-2    1105 larva L3 puffstage 3-6    1982 larva L3 puffstage 7-9    2299 white prepupae new    2599 white prepupae 12hr    3119 white prepupae 24hr    3706 pupae 2d postWPP    3112 pupae 3d postWPP    2095 pupae 4d postWPP    2212 adult male 01day    2972 adult male 05day    3937 adult male 30day    3884 adult female 01day    1773 adult female 05day    2218 adult female 30day    2250 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (3850) embryo 02-04hr  (2943) embryo 04-06hr  (2761) embryo 06-08hr  (2653) embryo 08-10hr  (2373) embryo 10-12hr  (2138) embryo 12-14hr  (1755) embryo 14-16hr  (2032) embryo 16-18hr  (1536) embryo 18-20hr  (1416) embryo 20-22hr  (1221) embryo 22-24hr  (1250) larva L1  (1252) larva L2  (916) larva L3 12hr old  (801) larva L3 puffstage 1-2  (1105) larva L3 puffstage 3-6  (1982) larva L3 puffstage 7-9  (2299) white prepupae new  (2599) white prepupae 12hr  (3119) white prepupae 24hr  (3706) pupae 2d postWPP  (3112) pupae 3d postWPP  (2095) pupae 4d postWPP  (2212) adult male 01day  (2972) adult male 05day  (3937) adult male 30day  (3884) adult female 01day  (1773) adult female 05day  (2218) adult female 30day  (2250) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (3850) embryo 02-04hr  (2943) embryo 04-06hr  (2761) embryo 06-08hr  (2653) embryo 08-10hr  2373 embryo 10-12hr  2138 embryo 12-14hr  1755 embryo 14-16hr  2032 embryo 16-18hr  1536 embryo 18-20hr  1416 embryo 20-22hr    1221 embryo 22-24hr    1250 larva L1    1252 larva L2    916 larva L3 12hr old    801 larva L3 puffstage 1-2    1105 larva L3 puffstage 3-6  1982 larva L3 puffstage 7-9  2299 white prepupae new  (2599) white prepupae 12hr  (3119) white prepupae 24hr  (3706) pupae 2d postWPP  (3112) pupae 3d postWPP  2095 pupae 4d postWPP  2212 adult male 01day  (2972) adult male 05day  (3937) adult male 30day  (3884) adult female 01day  1773 adult female 05day  2218 adult female 30day  2250 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    3850 embryo 02-04hr    2943 embryo 04-06hr    2761 embryo 06-08hr    2653 embryo 08-10hr    2373 embryo 10-12hr    2138 embryo 12-14hr    1755 embryo 14-16hr    2032 embryo 16-18hr    1536 embryo 18-20hr    1416 embryo 20-22hr    1221 embryo 22-24hr    1250 larva L1    1252 larva L2    916 larva L3 12hr old    801 larva L3 puffstage 1-2    1105 larva L3 puffstage 3-6    1982 larva L3 puffstage 7-9    2299 white prepupae new    2599 white prepupae 12hr    3119 white prepupae 24hr    3706 pupae 2d postWPP    3112 pupae 3d postWPP    2095 pupae 4d postWPP    2212 adult male 01day    2972 adult male 05day    3937 adult male 30day    3884 adult female 01day    1773 adult female 05day    2218 adult female 30day    2250 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    3850 embryo 02-04hr    2943 embryo 04-06hr    2761 embryo 06-08hr    2653 embryo 08-10hr    2373 embryo 10-12hr    2138 embryo 12-14hr    1755 embryo 14-16hr    2032 embryo 16-18hr    1536 embryo 18-20hr    1416 embryo 20-22hr    1221 embryo 22-24hr    1250 larva L1    1252 larva L2    916 larva L3 12hr old    801 larva L3 puffstage 1-2    1105 larva L3 puffstage 3-6    1982 larva L3 puffstage 7-9    2299 white prepupae new    2599 white prepupae 12hr    3119 white prepupae 24hr    3706 pupae 2d postWPP    3112 pupae 3d postWPP    2095 pupae 4d postWPP    2212 adult male 01day    2972 adult male 05day    3937 adult male 30day    3884 adult female 01day    1773 adult female 05day    2218 adult female 30day    2250 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0035437    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0035437 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult testis. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male accessory gland, larval/adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0035437 expression level Tissue   Expression Level Larval Central Nervous System    326.05 Larval Midgut    190.9 Larval Hindgut    236.1 Larval Malpighian Tubules    217.5 Larval Fat Body    232.7 Larval Salivary Gland    266.3 Larval Trachea    202.775 Larval Carcass    278.575 Adult Head    187.3 Adult Eye    181.2 Adult Brain    276.4 Adult Thoracic-Abdominal Ganglion    229.5 Adult Crop    269.4 Adult Midgut    168.9 Adult Hindgut    227.1 Adult Malpighian Tubules    203.3 Adult Fat Body    164.6 Adult Salivary Gland    315.2 Adult Heart    175.725 Adult VirginFemale Spermatheca    185 Adult InseminatedFemale Spermatheca    193.1 Adult Ovary    285.7 Adult Testis    871.4 Adult Male Accessory Gland    240.4 Adult Carcass    169.4 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    326.05 Larval Midgut    190.9 Larval Hindgut    236.1 Larval Malpighian Tubules    217.5 Larval Fat Body    232.7 Larval Salivary Gland    266.3 Larval Trachea    202.775 Larval Carcass    278.575 Adult Head    187.3 Adult Eye    181.2 Adult Brain    276.4 Adult Thoracic-Abdominal Ganglion    229.5 Adult Crop    269.4 Adult Midgut    168.9 Adult Hindgut    227.1 Adult Malpighian Tubules    203.3 Adult Fat Body    164.6 Adult Salivary Gland    315.2 Adult Heart    175.725 Adult VirginFemale Spermatheca    185 Adult InseminatedFemale Spermatheca    193.1 Adult Ovary    285.7 Adult Testis  (871.4) Adult Male Accessory Gland    240.4 Adult Carcass    169.4 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    326.05 Larval Midgut    190.9 Larval Hindgut    236.1 Larval Malpighian Tubules    217.5 Larval Fat Body    232.7 Larval Salivary Gland    266.3 Larval Trachea    202.775 Larval Carcass    278.575 Adult Head    187.3 Adult Eye    181.2 Adult Brain    276.4 Adult Thoracic-Abdominal Ganglion    229.5 Adult Crop    269.4 Adult Midgut    168.9 Adult Hindgut    227.1 Adult Malpighian Tubules    203.3 Adult Fat Body    164.6 Adult Salivary Gland    315.2 Adult Heart    175.725 Adult VirginFemale Spermatheca    185 Adult InseminatedFemale Spermatheca    193.1 Adult Ovary    285.7 Adult Testis    871.4 Adult Male Accessory Gland    240.4 Adult Carcass    169.4 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    326.05 Larval Midgut    190.9 Larval Hindgut    236.1 Larval Malpighian Tubules    217.5 Larval Fat Body    232.7 Larval Salivary Gland    266.3 Larval Trachea    202.775 Larval Carcass    278.575 Adult Head    187.3 Adult Eye    181.2 Adult Brain    276.4 Adult Thoracic-Abdominal Ganglion    229.5 Adult Crop    269.4 Adult Midgut    168.9 Adult Hindgut    227.1 Adult Malpighian Tubules    203.3 Adult Fat Body    164.6 Adult Salivary Gland    315.2 Adult Heart    175.725 Adult VirginFemale Spermatheca    185 Adult InseminatedFemale Spermatheca    193.1 Adult Ovary    285.7 Adult Testis    871.4 Adult Male Accessory Gland    240.4 Adult Carcass    169.4 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0035437 expression level Tissue   Expression Level Larval Central Nervous System    326.05 Larval Midgut    190.9 Larval Hindgut    236.1 Larval Malpighian Tubules    217.5 Larval Fat Body    232.7 Larval Salivary Gland    266.3 Larval Trachea    202.775 Larval Carcass    278.575 Adult Head    187.3 Adult Eye    181.2 Adult Brain    276.4 Adult Thoracic-Abdominal Ganglion    229.5 Adult Crop    269.4 Adult Midgut    168.9 Adult Hindgut    227.1 Adult Malpighian Tubules    203.3 Adult Fat Body    164.6 Adult Salivary Gland    315.2 Adult Heart    175.725 Adult VirginFemale Spermatheca    185 Adult InseminatedFemale Spermatheca    193.1 Adult Ovary    285.7 Adult Testis    871.4 Adult Male Accessory Gland    240.4 Adult Carcass    169.4 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    326.05 Larval Midgut    190.9 Larval Hindgut    236.1 Larval Malpighian Tubules    217.5 Larval Fat Body    232.7 Larval Salivary Gland    266.3 Larval Trachea    202.775 Larval Carcass    278.575 Adult Head    187.3 Adult Eye    181.2 Adult Brain    276.4 Adult Thoracic-Abdominal Ganglion    229.5 Adult Crop    269.4 Adult Midgut    168.9 Adult Hindgut    227.1 Adult Malpighian Tubules    203.3 Adult Fat Body    164.6 Adult Salivary Gland    315.2 Adult Heart    175.725 Adult VirginFemale Spermatheca    185 Adult InseminatedFemale Spermatheca    193.1 Adult Ovary    285.7 Adult Testis  (871.4) Adult Male Accessory Gland    240.4 Adult Carcass    169.4 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    326.05 Larval Midgut    190.9 Larval Hindgut    236.1 Larval Malpighian Tubules    217.5 Larval Fat Body    232.7 Larval Salivary Gland    266.3 Larval Trachea    202.775 Larval Carcass    278.575 Adult Head    187.3 Adult Eye    181.2 Adult Brain    276.4 Adult Thoracic-Abdominal Ganglion    229.5 Adult Crop    269.4 Adult Midgut    168.9 Adult Hindgut    227.1 Adult Malpighian Tubules    203.3 Adult Fat Body    164.6 Adult Salivary Gland    315.2 Adult Heart    175.725 Adult VirginFemale Spermatheca    185 Adult InseminatedFemale Spermatheca    193.1 Adult Ovary    285.7 Adult Testis    871.4 Adult Male Accessory Gland    240.4 Adult Carcass    169.4 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    326.05 Larval Midgut    190.9 Larval Hindgut    236.1 Larval Malpighian Tubules    217.5 Larval Fat Body    232.7 Larval Salivary Gland    266.3 Larval Trachea    202.775 Larval Carcass    278.575 Adult Head    187.3 Adult Eye    181.2 Adult Brain    276.4 Adult Thoracic-Abdominal Ganglion    229.5 Adult Crop    269.4 Adult Midgut    168.9 Adult Hindgut    227.1 Adult Malpighian Tubules    203.3 Adult Fat Body    164.6 Adult Salivary Gland    315.2 Adult Heart    175.725 Adult VirginFemale Spermatheca    185 Adult InseminatedFemale Spermatheca    193.1 Adult Ovary    285.7 Adult Testis    871.4 Adult Male Accessory Gland    240.4 Adult Carcass    169.4 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    187.3   NA  Eye    181.2   NA  Brain    276.4   326.05  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    229.5   NA  Crop    269.4   190.9  Midgut    168.9   236.1  Hindgut    227.1   217.5  Malpighian Tubules    203.3   232.7  Fat Body    164.6   266.3  Salivary Gland    315.2   NA  Heart    175.725   202.775  Trachea    NA   NA  VirginFemale Spermatheca    185   NA  InseminatedFemale Spermatheca    193.1   NA  Ovary    285.7   NA  Testis    871.4   NA  Male Accessory Gland    240.4   278.575  Carcass    169.4 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_21
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0035437 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG11526-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal | pupal stage, with Scer\GAL4pnr-MD237 CG11526GD7322 viable CG11526CB02228 CG11526e04482 CG11526f01271 Sterility Allele fertile CG11526e04482 CG11526f01271 Phenotype manifest in Allele
Classical Alleles ( 4 )
For All Classical Alleles Show
Allele of CG11526 Class Mutagen Stocks Known lesion CG11526e04482 piggyBac transposase 2 -- CG11526f01271 piggyBac transposase 1 -- CG11526G7172 P-element activity 1 -- CG11526CB02228 P-element activity 0 Yes
Alleles Carried on Transgenic Constructs ( 3 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG11526 Class Mutagen Stocks Known lesion CG11526GD7322 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes CG11526HMS01134 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG11526KK102069 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes
Aneuploid Aberrations
Disrupted in	Df(3L)Exel6093 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD7322} NA P{KK102069} NA P{TRiP.HMS01134} NA
Insertions
	Type of insertions Name Expression data miscellaneous insertions P{PTT-GB}CG11526CB02228 NA PBac{RB}CG11526e04482 NA PBac{WH}CG11526f01271 NA insertion of mobile activating element P{EP}PHGPxG7172 NA
Gene Ontology: Function, Process & Cellular Component ( 0 unique terms )
	There is no information supporting a biological process, cellular component or molecular function term for this gene. (Based on a review of available data on: 2010-03-25)
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 0 terms )
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG11526 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 63908 DroID - A comprehensive database of gene and protein interactions. • FBgn0035437 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 38412
Orthologs
Genome-wide drosophilid orthologs	Dana\GF23912 Dere\GG14265 Dgri\GH15524 Dmoj\GI16801 Dper\GL16094 Dpse\GA11051 Dsec\GM14058 Dsim\GD13333 Dvir\GJ12546 Dwil\GK20380 Dyak\GE20691
Curated drosophilid orthologs	Dpse\GA11051
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL007865-PA Aedes aegypti (mosquito) AGAP007902-PA Anopheles gambiae (mosquito) XP_395792.3 Apis mellifera (honey bee) XP_001945255.1 Acyrthosiphon pisum (pea aphid) 27749 Batrachochytrium dendrobatidis (chytrid fungus) 57852 Branchiostoma floridae (lancelet) XP_001895341.1 Brugia malayi (roundworm nematode) BGIBMGA014340-PA Bombyx mori (silk worm) ENSBTAP00000027922 Bos taurus (bovine) CAL0000489 Candida albicans (a form of yeast) CN27266 Caenorhabditis brenneri (small nematode) CBP17719 Caenorhabditis briggsae (nematode) CE04363 Caenorhabditis elegans (worm) ENSCAFP00000029301 Canis familiaris (dog) CAGL0L04158g Candida glabrata (haploid yeast) ENSCINP00000011668 Ciona intestinalis (sea squirt) JA04584 Caenorhabditis japonica (nematode) cn01004 Cryptococcus neoformans (yeast-like fungus) CPIJ001494 Culex pipens (mosquito) ENSCPOP00000011495 Cavia porcellus (guinea pig) RP43003 Caenorhabditis remanei (nematode) ENSCSAVP00000005395 Ciona savignyi (sedentary tunicate) 164543 Capitella spl (polychaete worm) DDB0266831 Dictyostelium discoideum (amoeba) DEHA2B06160g Debaryomyces Hansenii (yeast) 302834 Daphnia pulex (daphnia) ENSDARP00000075986 Danio rerio (zebra fish) ENSDARP00000096834 Danio rerio (zebra fish) ENSECAP00000022501 Equus caballus (horse) ENSGACP00000001338 Gymnopilus aculeatus (mushroom) ENSGALP00000012925 Gallus gallus (chicken) ENSP00000358810 Homo sapiens (human) ISCW006739-PA Ixodes scapularis (deer tick) KLLA0F24244g Kluyveromyces lactis (yeast) 221410 Lottia gigantea (owl limpet) ENSMODP00000002197 Monodelphis domestica (gray opossum) ENSMMUP00000007172 Macaca mulatta (rhesus monkey) ENSMUSP00000068587 Mus musculus (house mouse) XP_001603859.1 Nasonia vitripennis (wasp) ENSOANP00000009368 Ornithorynchus anatinus (platypus) ENSORLP00000000490 Oryzias latipes (japanese killifish) PHUM001452-PA Pediculus humanus (human body louse) PP19105 Pristionchus pacificus (nematode) ENSPPYP00000001226 Pongo pygmaeus (orangutan) 74441 Phytophthora ramorum (sudden oak death pathogen) 140058 Phytophthora sojae (root rot pathogen) ENSPTRP00000001850 Pan troglodytes (chimpanzee) ENSRNOP00000025036 Rattus norvegicus (norway rat) Smp_169400 Schistosoma mansoni (trematode parasite) SPBC27B12.04c Schizosaccharomyces pombe (fission yeast) XP_785913.2 Strongylocentrotus purpuratus (purple sea urchin) 23499 Trichoplax adhaerens (metazoa) XP_001815164.1 Tribolium castaneum (red flour beetle) ENSTNIP00000017668 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000020474 Takifugu rubripes (pufferfish Takifugu) YALI0C09779g Yarrowia lipolytica (nonconventional yeast) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB17338 NV14392 LH16466 ISCW006739 FBgn0237996 FBgn0222377 FBgn0199786 FBgn0185049 FBgn0168987 JGI_V11_302834 FBgn0071106 FBgn0153698 FBgn0139548 FBgn0122996 FBgn0106526 FBgn0100906 CPIJ001494 BGIBMGA014340 ACYPI006104 GB15232 AGAP007902 AAEL007865 PHUM229220 GLEAN_10759
Stocks & Reagents
Stocks Listed in FlyBase ( 8 )
Bloomington	18264 w1118; PBac{RB}CG11526e04482 34657 y1 sc* v1; P{TRiP.HMS01134}attP2 28479 y1 w*; P{EP}PHGPxG7172 CG11526G7172
Harvard	- PBac{RB}CG11526e04482 - PBac{WH}CG11526f01271
VDRC	v106184 P{KK102069}VIE-260B v16211 w1118; P{GD7322}v16211 v16212 w1118; P{GD7322}v16212
Genomic Clones ( 2 )
	BACR17M19 BACR19M09 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 95 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	AT20596 AT25231
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT02825 AT05776 AT07835 AT10168 AT11460 AT11848 AT13115 AT15595 AT16358 AT18433 AT18786 AT21713 AT21863 AT27738 AT28742 AT28964 AT29166 AT30671 LD04377 LP19263 LP19515 RE11083 RE11793 RE12937 RE34974 RE37023 RE38932 RE45146 RE51670 RE51968 RE56281 RE59442 RE66132 RE66624 RE66681 RE66859 RE68173 RE71855 RE75069 RH09274 RH17858 RH25379 RH25524 RH32135 RH33275 RH33486 RH33651 RH37624 RH38462 RH39453 RH39771 RH41648 RH42852 SD01723
Other clones	1355 16532 53480 74717 104145 120191 166019 173531 181137 214213.15 214257.22 214541.15 282364 bs39c03 CK01.25C.E6 CK01.34B.G10 CK01.60C.E5 CK01.142A.D3 EK029244 EK048819 EK063619 EK069552 EK091305 EK118514 EK122627 EK204925 EK227560 EK239833 EK277745 EK291259 EK307843 EP15433 EP15916 EP22224 ESG017d.E21_G03 ESG0113b.B21.1_F11 RC0-DP0006-150700-011-F02 SD05886 UT01892
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0035437 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 38412
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_139549 NM_168023 RefSeq (Proteins) • NP_647806 NP_728867 DDBJ / EMBL / GenBank • AAF47760 AAN11560 AI533904 AW944441 BF486331 BF489275 CZ482245 Entrez Gene - A searchable database of RefSeq genes. • 38412 UniProtKB/TrEMBL • Q8IRD5 Q9VZQ9
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • N1221-like (IPR012486) Protein of unknown function DUF3402 (IPR021819)
Linkouts
	BioGRID - A database of protein and genetic interactions • 63908 DroID - A comprehensive database of gene and protein interactions. • FBgn0035437 DRSC - Results from RNAi screens. • FBgn0035437 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0035437 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG11526-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0035437 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 38412 InParanoid A subset of ortholog calls from InParanoid. • AAEL007865-PA Aedes aegypti (mosquito) AGAP007902-PA Anopheles gambiae (mosquito) XP_395792.3 Apis mellifera (honey bee) XP_001945255.1 Acyrthosiphon pisum (pea aphid) 27749 Batrachochytrium dendrobatidis (chytrid fungus) 57852 Branchiostoma floridae (lancelet) XP_001895341.1 Brugia malayi (roundworm nematode) BGIBMGA014340-PA Bombyx mori (silk worm) ENSBTAP00000027922 Bos taurus (bovine) CAL0000489 Candida albicans (a form of yeast) CN27266 Caenorhabditis brenneri (small nematode) CBP17719 Caenorhabditis briggsae (nematode) CE04363 Caenorhabditis elegans (worm) ENSCAFP00000029301 Canis familiaris (dog) CAGL0L04158g Candida glabrata (haploid yeast) ENSCINP00000011668 Ciona intestinalis (sea squirt) JA04584 Caenorhabditis japonica (nematode) cn01004 Cryptococcus neoformans (yeast-like fungus) CPIJ001494 Culex pipens (mosquito) ENSCPOP00000011495 Cavia porcellus (guinea pig) RP43003 Caenorhabditis remanei (nematode) ENSCSAVP00000005395 Ciona savignyi (sedentary tunicate) 164543 Capitella spl (polychaete worm) DDB0266831 Dictyostelium discoideum (amoeba) DEHA2B06160g Debaryomyces Hansenii (yeast) 302834 Daphnia pulex (daphnia) ENSDARP00000075986 Danio rerio (zebra fish) ENSDARP00000096834 Danio rerio (zebra fish) ENSECAP00000022501 Equus caballus (horse) ENSGACP00000001338 Gymnopilus aculeatus (mushroom) ENSGALP00000012925 Gallus gallus (chicken) ENSP00000358810 Homo sapiens (human) ISCW006739-PA Ixodes scapularis (deer tick) KLLA0F24244g Kluyveromyces lactis (yeast) 221410 Lottia gigantea (owl limpet) ENSMODP00000002197 Monodelphis domestica (gray opossum) ENSMMUP00000007172 Macaca mulatta (rhesus monkey) ENSMUSP00000068587 Mus musculus (house mouse) XP_001603859.1 Nasonia vitripennis (wasp) ENSOANP00000009368 Ornithorynchus anatinus (platypus) ENSORLP00000000490 Oryzias latipes (japanese killifish) PHUM001452-PA Pediculus humanus (human body louse) PP19105 Pristionchus pacificus (nematode) ENSPPYP00000001226 Pongo pygmaeus (orangutan) 74441 Phytophthora ramorum (sudden oak death pathogen) 140058 Phytophthora sojae (root rot pathogen) ENSPTRP00000001850 Pan troglodytes (chimpanzee) ENSRNOP00000025036 Rattus norvegicus (norway rat) Smp_169400 Schistosoma mansoni (trematode parasite) SPBC27B12.04c Schizosaccharomyces pombe (fission yeast) XP_785913.2 Strongylocentrotus purpuratus (purple sea urchin) 23499 Trichoplax adhaerens (metazoa) XP_001815164.1 Tribolium castaneum (red flour beetle) ENSTNIP00000017668 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000020474 Takifugu rubripes (pufferfish Takifugu) YALI0C09779g Yarrowia lipolytica (nonconventional yeast) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 38412 modMine - Data generated by the modENCODE project. • FBgn0035437 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB17338 NV14392 LH16466 ISCW006739 FBgn0237996 FBgn0222377 FBgn0199786 FBgn0185049 FBgn0168987 JGI_V11_302834 FBgn0071106 FBgn0153698 FBgn0139548 FBgn0122996 FBgn0106526 FBgn0100906 CPIJ001494 BGIBMGA014340 ACYPI006104 GB15232 AGAP007902 AAEL007865 PHUM229220 GLEAN_10759
Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	CG11526 (Buszczak et al., 2007, Keleman et al., 2009.8.5, Ribeiro et al., 2010, Ni et al., 2010.12.1)
Name Synonym
Secondary FlyBase IDs
References ( 17 )
Research paper	Ribeiro et al., 2010, Mol. Cell 39(4): 521--534 Combined Functional Genomic and Proteomic Approaches Identify a PP2A Complex as a Negative Regulator of Hippo Signaling. [FBrf0211636] Buszczak et al., 2007, Genetics 175(3): 1505--1531 The Carnegie protein trap library: A versatile tool for Drosophila developmental studies. [FBrf0200345]
Supplementary material	The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518] Giot et al., 2003, Science 302(5651): Tables S1 to S7. [FBrf0166452]
Personal communication to FlyBase	Ni et al., 2010.12.1, A genome-scale shRNA resource for transgenic RNAi in Drosophila. A genome-scale shRNA resource for transgenic RNAi in Drosophila. [FBrf0212437] Bellen, 2009.8.20, BDGP_2009_0825.GenExel.xml BDGP_2009_0825.GenExel.xml [FBrf0208536] Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] Bloomington Drosophila Stock Center, 2004.11.6, Exelixis insertion alleles that are not in FlyBase. Exelixis insertion alleles that are not in FlyBase. [FBrf0179797] Ryder, 2004.4.26, Exelixis CG deletion data. Exelixis CG deletion data. [FBrf0184335]
FlyBase analysis	FlyBase Curators, 2002-, Use of the ND evidence code for Gene Ontology (GO) terms in FlyBase. Use of the ND evidence code for Gene Ontology (GO) terms in FlyBase. [FBrf0159398] FlyBase, 1992-, FlyBase curation FlyBase curation. [FBrf0105495]
Computer file	Gene Disruption Project members and Exelixis, 2005, Genomic mapping of Exelixis insertion collection. Genomic mapping of Exelixis insertion collection. [FBrf0184340] Gene Disruption Project members, 2001-, [title not yet available] [title not yet available] [FBrf0132177] BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. Berkeley Drosophila Genome Project. [FBrf0125078]