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Gene Dmel\Cpr64Ab

General Information
Symbol	Dmel\Cpr64Ab	Species	D. melanogaster
Name	Cuticular protein 64Ab	Annotation symbol	CG15007
Feature type	protein_coding_gene	FlyBase ID	FBgn0035511
Gene Model Status	Current	Stock availability	2 publicly available
Genomic Location
Chromosome (arm)	3L	Recombination map
Cytogenetic map	64A10-64A10	Sequence location	3L:4,210,880..4,211,540 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene Cuticular protein 64Ab is referred to in FlyBase by the symbol Dmel\Cpr64Ab (CG15007, FBgn0035511). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: structural constituent of chitin-based cuticle; structural constituent of chitin-based larval cuticle. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Insect cuticle protein. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of extremely low expression. Peak expression observed within 12-24 hour embryonic stages, during early larval stages, during late pupal stages. Summary of FlyAtlas Anatomical Expression Data: Little or no expression detected in any larval or adult organs/tissues. Comments on Affy2 ProbeSet: ProbeSet 1629394_at partially aligns to an exonic region of the only FlyBase-annotated transcript isoform of Cpr64Ab: 12 out of 13 probes fall into this exonic region. Gene sequence location is 3L:4210880..4211540.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 64A10-64A10   Limits computationally determined from genome sequence between P{PZ}l(3)rG166rG166 and P{PZ}sinu06524
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\Cpr64Ab for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.46
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) Cpr64Ab-RA FBtr0073253  NM_139616   552   120
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein Cpr64Ab-PA   FBpp0073109   12.5   120   4.41     NP_647873   AAF47862
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Insect cuticle protein (IPR000618)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE014296 AAF47862   BT022916   CO187298   CO288537   EC087252   EC206489   EC207385   EC207552
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9VZG1
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
mass spectroscopy Stage Tissue/Position (including subcellular localization) Reference day 7 of adulthood -- day 49 of adulthood   adult heart   (Cammarato et al., 2011)
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Little or no expression detected in any larval or adult organs/tissues. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    15.925 Larval Midgut    21.8 Larval Hindgut    44.7 Larval Malpighian Tubules    17.8 Larval Fat Body    8.9 Larval Salivary Gland    9 Larval Trachea    16.65 Larval Carcass    39.875 Adult Head    16.3 Adult Eye    8.9 Adult Brain    11.1 Adult Thoracic-Abdominal Ganglion    10.4 Adult Crop    24.7 Adult Midgut    28.2 Adult Hindgut    17.4 Adult Malpighian Tubules    18.2 Adult Fat Body    24.4 Adult Salivary Gland    28.4 Adult Heart    9.525 Adult VirginFemale Spermatheca    8.2 Adult InseminatedFemale Spermatheca    17.1 Adult Ovary    13.4 Adult Testis    6.4 Adult Male Accessory Gland    9.6 Adult Carcass    22.5 Expression Level Scale  None   Low  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    15.925 Larval Midgut    21.8 Larval Hindgut    44.7 Larval Malpighian Tubules    17.8 Larval Fat Body    8.9 Larval Salivary Gland    9 Larval Trachea    16.65 Larval Carcass    39.875 Adult Head    16.3 Adult Eye    8.9 Adult Brain    11.1 Adult Thoracic-Abdominal Ganglion    10.4 Adult Crop    24.7 Adult Midgut    28.2 Adult Hindgut    17.4 Adult Malpighian Tubules    18.2 Adult Fat Body    24.4 Adult Salivary Gland    28.4 Adult Heart    9.525 Adult VirginFemale Spermatheca    8.2 Adult InseminatedFemale Spermatheca    17.1 Adult Ovary    13.4 Adult Testis    6.4 Adult Male Accessory Gland    9.6 Adult Carcass    22.5 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    15.925 Larval Midgut    21.8 Larval Hindgut    44.7 Larval Malpighian Tubules    17.8 Larval Fat Body    8.9 Larval Salivary Gland    9 Larval Trachea    16.65 Larval Carcass    39.875 Adult Head    16.3 Adult Eye    8.9 Adult Brain    11.1 Adult Thoracic-Abdominal Ganglion    10.4 Adult Crop    24.7 Adult Midgut    28.2 Adult Hindgut    17.4 Adult Malpighian Tubules    18.2 Adult Fat Body    24.4 Adult Salivary Gland    28.4 Adult Heart    9.525 Adult VirginFemale Spermatheca    8.2 Adult InseminatedFemale Spermatheca    17.1 Adult Ovary    13.4 Adult Testis    6.4 Adult Male Accessory Gland    9.6 Adult Carcass    22.5 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    15.925 Larval Midgut    21.8 Larval Hindgut    44.7 Larval Malpighian Tubules    17.8 Larval Fat Body    8.9 Larval Salivary Gland    9 Larval Trachea    16.65 Larval Carcass    39.875 Adult Head    16.3 Adult Eye    8.9 Adult Brain    11.1 Adult Thoracic-Abdominal Ganglion    10.4 Adult Crop    24.7 Adult Midgut    28.2 Adult Hindgut    17.4 Adult Malpighian Tubules    18.2 Adult Fat Body    24.4 Adult Salivary Gland    28.4 Adult Heart    9.525 Adult VirginFemale Spermatheca    8.2 Adult InseminatedFemale Spermatheca    17.1 Adult Ovary    13.4 Adult Testis    6.4 Adult Male Accessory Gland    9.6 Adult Carcass    22.5 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    15.925 Larval Midgut    21.8 Larval Hindgut    44.7 Larval Malpighian Tubules    17.8 Larval Fat Body    8.9 Larval Salivary Gland    9 Larval Trachea    16.65 Larval Carcass    39.875 Adult Head    16.3 Adult Eye    8.9 Adult Brain    11.1 Adult Thoracic-Abdominal Ganglion    10.4 Adult Crop    24.7 Adult Midgut    28.2 Adult Hindgut    17.4 Adult Malpighian Tubules    18.2 Adult Fat Body    24.4 Adult Salivary Gland    28.4 Adult Heart    9.525 Adult VirginFemale Spermatheca    8.2 Adult InseminatedFemale Spermatheca    17.1 Adult Ovary    13.4 Adult Testis    6.4 Adult Male Accessory Gland    9.6 Adult Carcass    22.5 Expression Level Scale  None   Low  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    15.925 Larval Midgut    21.8 Larval Hindgut    44.7 Larval Malpighian Tubules    17.8 Larval Fat Body    8.9 Larval Salivary Gland    9 Larval Trachea    16.65 Larval Carcass    39.875 Adult Head    16.3 Adult Eye    8.9 Adult Brain    11.1 Adult Thoracic-Abdominal Ganglion    10.4 Adult Crop    24.7 Adult Midgut    28.2 Adult Hindgut    17.4 Adult Malpighian Tubules    18.2 Adult Fat Body    24.4 Adult Salivary Gland    28.4 Adult Heart    9.525 Adult VirginFemale Spermatheca    8.2 Adult InseminatedFemale Spermatheca    17.1 Adult Ovary    13.4 Adult Testis    6.4 Adult Male Accessory Gland    9.6 Adult Carcass    22.5 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    15.925 Larval Midgut    21.8 Larval Hindgut    44.7 Larval Malpighian Tubules    17.8 Larval Fat Body    8.9 Larval Salivary Gland    9 Larval Trachea    16.65 Larval Carcass    39.875 Adult Head    16.3 Adult Eye    8.9 Adult Brain    11.1 Adult Thoracic-Abdominal Ganglion    10.4 Adult Crop    24.7 Adult Midgut    28.2 Adult Hindgut    17.4 Adult Malpighian Tubules    18.2 Adult Fat Body    24.4 Adult Salivary Gland    28.4 Adult Heart    9.525 Adult VirginFemale Spermatheca    8.2 Adult InseminatedFemale Spermatheca    17.1 Adult Ovary    13.4 Adult Testis    6.4 Adult Male Accessory Gland    9.6 Adult Carcass    22.5 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    15.925 Larval Midgut    21.8 Larval Hindgut    44.7 Larval Malpighian Tubules    17.8 Larval Fat Body    8.9 Larval Salivary Gland    9 Larval Trachea    16.65 Larval Carcass    39.875 Adult Head    16.3 Adult Eye    8.9 Adult Brain    11.1 Adult Thoracic-Abdominal Ganglion    10.4 Adult Crop    24.7 Adult Midgut    28.2 Adult Hindgut    17.4 Adult Malpighian Tubules    18.2 Adult Fat Body    24.4 Adult Salivary Gland    28.4 Adult Heart    9.525 Adult VirginFemale Spermatheca    8.2 Adult InseminatedFemale Spermatheca    17.1 Adult Ovary    13.4 Adult Testis    6.4 Adult Male Accessory Gland    9.6 Adult Carcass    22.5 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    no informative data   NA  Eye    8.9   NA  Brain    no informative data   no informative data  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    no informative data   NA  Crop    no informative data   no informative data  Midgut    no informative data   44.7  Hindgut    no informative data   no informative data  Malpighian Tubules    no informative data   8.9  Fat Body    no informative data   9  Salivary Gland    no informative data   NA  Heart    9.525   no informative data  Trachea    NA   NA  VirginFemale Spermatheca    8.2   NA  InseminatedFemale Spermatheca    no informative data   NA  Ovary    no informative data   NA  Testis    6.4   NA  Male Accessory Gland    9.6   39.875  Carcass    no informative data FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of extremely low expression. Peak expression observed within 12-24 hour embryonic stages, during early larval stages, during late pupal stages. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    1 embryo 02-04hr    0 embryo 04-06hr    1 embryo 06-08hr    1 embryo 08-10hr    3 embryo 10-12hr    2 embryo 12-14hr    2 embryo 14-16hr    76 embryo 16-18hr    735 embryo 18-20hr    342 embryo 20-22hr    5 embryo 22-24hr    6 larva L1    6 larva L2    168 larva L3 12hr old    133 larva L3 puffstage 1-2    0 larva L3 puffstage 3-6    0 larva L3 puffstage 7-9    0 white prepupae new    0 white prepupae 12hr    4 white prepupae 24hr    3 pupae 2d postWPP    9 pupae 3d postWPP    222 pupae 4d postWPP    22 adult male 01day    0 adult male 05day    0 adult male 30day    0 adult female 01day    0 adult female 05day    0 adult female 30day    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    1 embryo 02-04hr    0 embryo 04-06hr    1 embryo 06-08hr    1 embryo 08-10hr    3 embryo 10-12hr    2 embryo 12-14hr    2 embryo 14-16hr  (76) embryo 16-18hr  (735) embryo 18-20hr  (342) embryo 20-22hr    5 embryo 22-24hr    6 larva L1    6 larva L2  (168) larva L3 12hr old  (133) larva L3 puffstage 1-2    0 larva L3 puffstage 3-6    0 larva L3 puffstage 7-9    0 white prepupae new    0 white prepupae 12hr    4 white prepupae 24hr    3 pupae 2d postWPP    9 pupae 3d postWPP  (222) pupae 4d postWPP    22 adult male 01day    0 adult male 05day    0 adult male 30day    0 adult female 01day    0 adult female 05day    0 adult female 30day    0 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    1 embryo 02-04hr    0 embryo 04-06hr    1 embryo 06-08hr    1 embryo 08-10hr    3 embryo 10-12hr    2 embryo 12-14hr    2 embryo 14-16hr    76 embryo 16-18hr  (735) embryo 18-20hr  (342) embryo 20-22hr    5 embryo 22-24hr    6 larva L1    6 larva L2  (168) larva L3 12hr old  (133) larva L3 puffstage 1-2    0 larva L3 puffstage 3-6    0 larva L3 puffstage 7-9    0 white prepupae new    0 white prepupae 12hr    4 white prepupae 24hr    3 pupae 2d postWPP    9 pupae 3d postWPP  (222) pupae 4d postWPP    22 adult male 01day    0 adult male 05day    0 adult male 30day    0 adult female 01day    0 adult female 05day    0 adult female 30day    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    1 embryo 02-04hr    0 embryo 04-06hr    1 embryo 06-08hr    1 embryo 08-10hr    3 embryo 10-12hr    2 embryo 12-14hr    2 embryo 14-16hr    76 embryo 16-18hr    735 embryo 18-20hr    342 embryo 20-22hr    5 embryo 22-24hr    6 larva L1    6 larva L2    168 larva L3 12hr old    133 larva L3 puffstage 1-2    0 larva L3 puffstage 3-6    0 larva L3 puffstage 7-9    0 white prepupae new    0 white prepupae 12hr    4 white prepupae 24hr    3 pupae 2d postWPP    9 pupae 3d postWPP    222 pupae 4d postWPP    22 adult male 01day    0 adult male 05day    0 adult male 30day    0 adult female 01day    0 adult female 05day    0 adult female 30day    0 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    1 embryo 02-04hr    0 embryo 04-06hr    1 embryo 06-08hr    1 embryo 08-10hr    3 embryo 10-12hr    2 embryo 12-14hr    2 embryo 14-16hr    76 embryo 16-18hr    735 embryo 18-20hr    342 embryo 20-22hr    5 embryo 22-24hr    6 larva L1    6 larva L2    168 larva L3 12hr old    133 larva L3 puffstage 1-2    0 larva L3 puffstage 3-6    0 larva L3 puffstage 7-9    0 white prepupae new    0 white prepupae 12hr    4 white prepupae 24hr    3 pupae 2d postWPP    9 pupae 3d postWPP    222 pupae 4d postWPP    22 adult male 01day    0 adult male 05day    0 adult male 30day    0 adult female 01day    0 adult female 05day    0 adult female 30day    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    1 embryo 02-04hr    0 embryo 04-06hr    1 embryo 06-08hr    1 embryo 08-10hr    3 embryo 10-12hr    2 embryo 12-14hr    2 embryo 14-16hr  (76) embryo 16-18hr  (735) embryo 18-20hr  (342) embryo 20-22hr    5 embryo 22-24hr    6 larva L1    6 larva L2  (168) larva L3 12hr old  (133) larva L3 puffstage 1-2    0 larva L3 puffstage 3-6    0 larva L3 puffstage 7-9    0 white prepupae new    0 white prepupae 12hr    4 white prepupae 24hr    3 pupae 2d postWPP    9 pupae 3d postWPP  (222) pupae 4d postWPP    22 adult male 01day    0 adult male 05day    0 adult male 30day    0 adult female 01day    0 adult female 05day    0 adult female 30day    0 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    1 embryo 02-04hr    0 embryo 04-06hr    1 embryo 06-08hr    1 embryo 08-10hr    3 embryo 10-12hr    2 embryo 12-14hr    2 embryo 14-16hr    76 embryo 16-18hr  (735) embryo 18-20hr  (342) embryo 20-22hr    5 embryo 22-24hr    6 larva L1    6 larva L2  (168) larva L3 12hr old  133 larva L3 puffstage 1-2    0 larva L3 puffstage 3-6    0 larva L3 puffstage 7-9    0 white prepupae new    0 white prepupae 12hr    4 white prepupae 24hr    3 pupae 2d postWPP    9 pupae 3d postWPP  (222) pupae 4d postWPP    22 adult male 01day    0 adult male 05day    0 adult male 30day    0 adult female 01day    0 adult female 05day    0 adult female 30day    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    1 embryo 02-04hr    0 embryo 04-06hr    1 embryo 06-08hr    1 embryo 08-10hr    3 embryo 10-12hr    2 embryo 12-14hr    2 embryo 14-16hr    76 embryo 16-18hr    735 embryo 18-20hr    342 embryo 20-22hr    5 embryo 22-24hr    6 larva L1    6 larva L2    168 larva L3 12hr old    133 larva L3 puffstage 1-2    0 larva L3 puffstage 3-6    0 larva L3 puffstage 7-9    0 white prepupae new    0 white prepupae 12hr    4 white prepupae 24hr    3 pupae 2d postWPP    9 pupae 3d postWPP    222 pupae 4d postWPP    22 adult male 01day    0 adult male 05day    0 adult male 30day    0 adult female 01day    0 adult female 05day    0 adult female 30day    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    0 cold shock, 4-day adult    0 heat shock, 4-day adult    0 Cadmium 50 mM 6 hrs, larvae L3    0 Cadmium 50 mM 12 hrs, larvae L3    0 Cadmium 50 mM 48 hrs, 4-day adult    0 Cadmium 100 mM 48 hrs, 4-day adult    0 Copper 0.5 mM 12 hrs, larvae L3    0 Copper 15 mM 48 hrs, 4-day adult    0 Zinc 5 mM 12 hrs, larvae L3    0 Zinc 4.5 mM 48 hrs, 4-day adult    0 Ethanol 2.5% 3 hrs, larvae L3    0 Ethanol 5% 3 hrs, larvae L3    0 Ethanol 10% 3 hrs, larvae L3    0 Caffeine 1.5 mg/ml 4 hrs, larvae L3    0 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    1 Caffeine 25 mg/ml 48 hrs, 4-day adult    0 Paraquat 5 mM 48 hrs, 4-day adult    1 Paraquat 10 mM 48 hrs, 4-day adult    2 Rotenone 2 μg 12 hrs, larvae L3    0 Rotenone 8 μg 12 hrs, larvae L3    0 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    0 cold shock, 4-day adult    0 heat shock, 4-day adult    0 Cadmium 50 mM 6 hrs, larvae L3    0 Cadmium 50 mM 12 hrs, larvae L3    0 Cadmium 50 mM 48 hrs, 4-day adult    0 Cadmium 100 mM 48 hrs, 4-day adult    0 Copper 0.5 mM 12 hrs, larvae L3    0 Copper 15 mM 48 hrs, 4-day adult    0 Zinc 5 mM 12 hrs, larvae L3    0 Zinc 4.5 mM 48 hrs, 4-day adult    0 Ethanol 2.5% 3 hrs, larvae L3    0 Ethanol 5% 3 hrs, larvae L3    0 Ethanol 10% 3 hrs, larvae L3    0 Caffeine 1.5 mg/ml 4 hrs, larvae L3    0 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    1 Caffeine 25 mg/ml 48 hrs, 4-day adult    0 Paraquat 5 mM 48 hrs, 4-day adult    1 Paraquat 10 mM 48 hrs, 4-day adult    2 Rotenone 2 μg 12 hrs, larvae L3    0 Rotenone 8 μg 12 hrs, larvae L3    0 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    0 cold shock, 4-day adult    0 heat shock, 4-day adult    0 Cadmium 50 mM 6 hrs, larvae L3    0 Cadmium 50 mM 12 hrs, larvae L3    0 Cadmium 50 mM 48 hrs, 4-day adult    0 Cadmium 100 mM 48 hrs, 4-day adult    0 Copper 0.5 mM 12 hrs, larvae L3    0 Copper 15 mM 48 hrs, 4-day adult    0 Zinc 5 mM 12 hrs, larvae L3    0 Zinc 4.5 mM 48 hrs, 4-day adult    0 Ethanol 2.5% 3 hrs, larvae L3    0 Ethanol 5% 3 hrs, larvae L3    0 Ethanol 10% 3 hrs, larvae L3    0 Caffeine 1.5 mg/ml 4 hrs, larvae L3    0 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    1 Caffeine 25 mg/ml 48 hrs, 4-day adult    0 Paraquat 5 mM 48 hrs, 4-day adult    1 Paraquat 10 mM 48 hrs, 4-day adult    2 Rotenone 2 μg 12 hrs, larvae L3    0 Rotenone 8 μg 12 hrs, larvae L3    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    0 cold shock, 4-day adult    0 heat shock, 4-day adult    0 Cadmium 50 mM 6 hrs, larvae L3    0 Cadmium 50 mM 12 hrs, larvae L3    0 Cadmium 50 mM 48 hrs, 4-day adult    0 Cadmium 100 mM 48 hrs, 4-day adult    0 Copper 0.5 mM 12 hrs, larvae L3    0 Copper 15 mM 48 hrs, 4-day adult    0 Zinc 5 mM 12 hrs, larvae L3    0 Zinc 4.5 mM 48 hrs, 4-day adult    0 Ethanol 2.5% 3 hrs, larvae L3    0 Ethanol 5% 3 hrs, larvae L3    0 Ethanol 10% 3 hrs, larvae L3    0 Caffeine 1.5 mg/ml 4 hrs, larvae L3    0 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    1 Caffeine 25 mg/ml 48 hrs, 4-day adult    0 Paraquat 5 mM 48 hrs, 4-day adult    1 Paraquat 10 mM 48 hrs, 4-day adult    2 Rotenone 2 μg 12 hrs, larvae L3    0 Rotenone 8 μg 12 hrs, larvae L3    0 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    0 cold shock, 4-day adult    0 heat shock, 4-day adult    0 Cadmium 50 mM 6 hrs, larvae L3    0 Cadmium 50 mM 12 hrs, larvae L3    0 Cadmium 50 mM 48 hrs, 4-day adult    0 Cadmium 100 mM 48 hrs, 4-day adult    0 Copper 0.5 mM 12 hrs, larvae L3    0 Copper 15 mM 48 hrs, 4-day adult    0 Zinc 5 mM 12 hrs, larvae L3    0 Zinc 4.5 mM 48 hrs, 4-day adult    0 Ethanol 2.5% 3 hrs, larvae L3    0 Ethanol 5% 3 hrs, larvae L3    0 Ethanol 10% 3 hrs, larvae L3    0 Caffeine 1.5 mg/ml 4 hrs, larvae L3    0 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    1 Caffeine 25 mg/ml 48 hrs, 4-day adult    0 Paraquat 5 mM 48 hrs, 4-day adult    1 Paraquat 10 mM 48 hrs, 4-day adult    2 Rotenone 2 μg 12 hrs, larvae L3    0 Rotenone 8 μg 12 hrs, larvae L3    0 Expression Level Scale  Very low   Low   Moderate  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    0 cold shock, 4-day adult    0 heat shock, 4-day adult    0 Cadmium 50 mM 6 hrs, larvae L3    0 Cadmium 50 mM 12 hrs, larvae L3    0 Cadmium 50 mM 48 hrs, 4-day adult    0 Cadmium 100 mM 48 hrs, 4-day adult    0 Copper 0.5 mM 12 hrs, larvae L3    0 Copper 15 mM 48 hrs, 4-day adult    0 Zinc 5 mM 12 hrs, larvae L3    0 Zinc 4.5 mM 48 hrs, 4-day adult    0 Ethanol 2.5% 3 hrs, larvae L3    0 Ethanol 5% 3 hrs, larvae L3    0 Ethanol 10% 3 hrs, larvae L3    0 Caffeine 1.5 mg/ml 4 hrs, larvae L3    0 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    1 Caffeine 25 mg/ml 48 hrs, 4-day adult    0 Paraquat 5 mM 48 hrs, 4-day adult    1 Paraquat 10 mM 48 hrs, 4-day adult    2 Rotenone 2 μg 12 hrs, larvae L3    0 Rotenone 8 μg 12 hrs, larvae L3    0 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    0 cold shock, 4-day adult    0 heat shock, 4-day adult    0 Cadmium 50 mM 6 hrs, larvae L3    0 Cadmium 50 mM 12 hrs, larvae L3    0 Cadmium 50 mM 48 hrs, 4-day adult    0 Cadmium 100 mM 48 hrs, 4-day adult    0 Copper 0.5 mM 12 hrs, larvae L3    0 Copper 15 mM 48 hrs, 4-day adult    0 Zinc 5 mM 12 hrs, larvae L3    0 Zinc 4.5 mM 48 hrs, 4-day adult    0 Ethanol 2.5% 3 hrs, larvae L3    0 Ethanol 5% 3 hrs, larvae L3    0 Ethanol 10% 3 hrs, larvae L3    0 Caffeine 1.5 mg/ml 4 hrs, larvae L3    0 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    1 Caffeine 25 mg/ml 48 hrs, 4-day adult    0 Paraquat 5 mM 48 hrs, 4-day adult    1 Paraquat 10 mM 48 hrs, 4-day adult    2 Rotenone 2 μg 12 hrs, larvae L3    0 Rotenone 8 μg 12 hrs, larvae L3    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    0 cold shock, 4-day adult    0 heat shock, 4-day adult    0 Cadmium 50 mM 6 hrs, larvae L3    0 Cadmium 50 mM 12 hrs, larvae L3    0 Cadmium 50 mM 48 hrs, 4-day adult    0 Cadmium 100 mM 48 hrs, 4-day adult    0 Copper 0.5 mM 12 hrs, larvae L3    0 Copper 15 mM 48 hrs, 4-day adult    0 Zinc 5 mM 12 hrs, larvae L3    0 Zinc 4.5 mM 48 hrs, 4-day adult    0 Ethanol 2.5% 3 hrs, larvae L3    0 Ethanol 5% 3 hrs, larvae L3    0 Ethanol 10% 3 hrs, larvae L3    0 Caffeine 1.5 mg/ml 4 hrs, larvae L3    0 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    1 Caffeine 25 mg/ml 48 hrs, 4-day adult    0 Paraquat 5 mM 48 hrs, 4-day adult    1 Paraquat 10 mM 48 hrs, 4-day adult    2 Rotenone 2 μg 12 hrs, larvae L3    0 Rotenone 8 μg 12 hrs, larvae L3    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_12 mE1_20_mRNA_expression_cluster_12
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0035511 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG15007-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele partially lethal - majority die | pupal stage, with Scer\GAL4pnr-MD237 Cpr64AbGD2295 Phenotype manifest in Allele
Classical Alleles ( 0 )
For All Classical Alleles Show
Allele of Cpr64Ab Class Mutagen Stocks Known lesion
Alleles Carried on Transgenic Constructs ( 2 )
For All Alleles Carried on Transgenic Constructs Show
Allele of Cpr64Ab Class Mutagen Stocks Known lesion Cpr64AbGD2295 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes Cpr64AbKK113267 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes
Aneuploid Aberrations
Disrupted in	Df(3L)Exel6100 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD2295} NA P{KK113267} NA
Insertions
	Type of insertions Name Expression data
Gene Ontology: Function, Process & Cellular Component ( 2 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 2 terms )
Molecular Function
CV term Evidence References
structural constituent of chitin-based cuticle inferred from sequence or structural similarity with InterPro:IPR000618 (Willis, 2007.1.3) inferred from sequence or structural similarity with Pfam:PF00379 (Willis, 2007.1.3) structural constituent of chitin-based larval cuticle inferred from sequence or structural similarity with UniProtKB:P81225 (FlyBase, 1992-)
Biological Process ( 0 terms)
Cellular Component ( 0 terms)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions Cpr64Ab allele Gene References
External Data
Linkouts	DroID - A comprehensive database of gene and protein interactions. • FBgn0035511
Orthologs
OrthoDB Orthologs (108) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6C5D54 Dipteran inclusive ortholog search EOG6PG69F Insect inclusive ortholog search EOG65HQVM Arthropod inclusive ortholog search EOG6C2FTR Metazoa inclusive ortholog search No orthologs identified
Orthologs in Drosophila Species (EOG6C5D54)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\Cpr64Ab     Drosophila simulans   Dsim\GD13279 Y   Drosophila sechellia   Dsec\GM13998 Y   Drosophila erecta   Dere\GG14206 Y   Drosophila yakuba   Dyak\GE20635 Y   Drosophila ananassae   Dana\GF23876 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA28204 Y   Drosophila willistoni   Dwil\GK10237 Y   Drosophila mojavensis   Dmoj\GI14579 Y   Drosophila mojavensis   Dmoj\GI16820     Drosophila grimshawi   Dgri\GH15545 Y
Orthologs in non-Drosophila Dipterans (EOG6PG69F)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL002110   Anopheles gambiae Malaria mosquito  Agam\CPR116   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ004289
Orthologs in non-Dipteran Insects (EOG65HQVM)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\GB48831 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG030700 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG007842 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG007836 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG007843 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG007838 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG007837 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG006814 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG007839 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG007840 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG017386 Y Atta cephalotes Leafcutter ant  Acep\ACEP13680 Y Camponotus floridanus Florida carpenter ant  Cflo\CFLO19315 Y Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL15296 Y Linepithema humile Argentine ant  Lhum\LH17528 Y Linepithema humile Argentine ant  Lhum\LH24656 Y Linepithema humile Argentine ant  Lhum\LH24658 Y Pogonomyrmex barbatus Red harvester ant  Pbar\PB19009 Y Solenopsis invicta Red fire ant  Sinv\SINV12605 Y Acyrthosiphon pisum Pea aphid  Apim\ACYPI000889 Y Acyrthosiphon pisum Pea aphid  Apim\ACYPI000291 Y Acyrthosiphon pisum Pea aphid  Apim\ACYPI000961 Y Acyrthosiphon pisum Pea aphid  Apim\ACYPI087743 Y Acyrthosiphon pisum Pea aphid  Apim\ACYPI56614 Y Acyrthosiphon pisum Pea aphid  Apim\ACYPI008524 Y Bombyx mori Silkmoth  Bmor\BmorCPR92 Y Bombyx mori Silkmoth  Bmor\BmorCPR73 Y Bombyx mori Silkmoth  Bmor\BGIBMGA000282 Y Bombyx mori Silkmoth  Bmor\BGIBMGA010145 Y Bombyx mori Silkmoth  Bmor\BmorCPR77 Y Bombyx mori Silkmoth  Bmor\BGIBMGA014295 Y Pediculus humanus Human body louse  Phum\PHUM492230 Y Pediculus humanus Human body louse  Phum\PHUM492240 Y Tribolium castaneum Red flour beetle  Tcas\TC003109 Y Tribolium castaneum Red flour beetle  Tcas\GLEAN_07724 Y Tribolium castaneum Red flour beetle  Tcas\TC010057 Y Tribolium castaneum Red flour beetle  Tcas\TC000720 Y Tribolium castaneum Red flour beetle  Tcas\TC000721 Y Tribolium castaneum Red flour beetle  Tcas\TC000722 Y Tribolium castaneum Red flour beetle  Tcas\TC011149 Y
Orthologs in non-Insect Arthropods (EOG6C2FTR)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\rbcL Y Daphnia pulex Water flea  Dpux\rbcL Y Daphnia pulex Water flea  Dpux\cytb Y Daphnia pulex Water flea  Dpux\COI Y Daphnia pulex Water flea  Dpux\JGI_V11_223022 Y Daphnia pulex Water flea  Dpux\COI Y Daphnia pulex Water flea  Dpux\JGI_V11_44737 Y Daphnia pulex Water flea  Dpux\JGI_V11_65439 Y Daphnia pulex Water flea  Dpux\JGI_V11_241286 Y Daphnia pulex Water flea  Dpux\JGI_V11_239782 Y Ixodes scapularis Deer tick  Isca\ISCW017292 Y Ixodes scapularis Deer tick  Isca\ISCW009307 Y Ixodes scapularis Deer tick  Isca\ISCW016297 Y Ixodes scapularis Deer tick  Isca\ISCW016301 Y Ixodes scapularis Deer tick  Isca\ISCW016305 Y Ixodes scapularis Deer tick  Isca\ISCW020946 Y Ixodes scapularis Deer tick  Isca\ISCW010523 Y Ixodes scapularis Deer tick  Isca\ISCW012784 Y Ixodes scapularis Deer tick  Isca\ISCW019772 Y Ixodes scapularis Deer tick  Isca\ISCW020941 Y Ixodes scapularis Deer tick  Isca\ISCW008453 Y Ixodes scapularis Deer tick  Isca\ISCW016957 Y Ixodes scapularis Deer tick  Isca\ISCW020433 Y Ixodes scapularis Deer tick  Isca\ISCW001420 Y Ixodes scapularis Deer tick  Isca\ISCW017291 Y Ixodes scapularis Deer tick  Isca\ISCW009312 Y Ixodes scapularis Deer tick  Isca\ISCW022373 Y Ixodes scapularis Deer tick  Isca\ISCW010521 Y Ixodes scapularis Deer tick  Isca\ISCW009803 Y Ixodes scapularis Deer tick  Isca\ISCW007105 Y Ixodes scapularis Deer tick  Isca\ISCW016308 Y Ixodes scapularis Deer tick  Isca\ISCW024011 Y Ixodes scapularis Deer tick  Isca\ISCW019773 Y Ixodes scapularis Deer tick  Isca\ISCW010074 Y Ixodes scapularis Deer tick  Isca\ISCW020947 Y Ixodes scapularis Deer tick  Isca\ISCW017289 Y Ixodes scapularis Deer tick  Isca\ISCW017294 Y Ixodes scapularis Deer tick  Isca\ISCW007407 Y Ixodes scapularis Deer tick  Isca\ISCW020948 Y Ixodes scapularis Deer tick  Isca\ISCW016304 Y Ixodes scapularis Deer tick  Isca\ISCW019781 Y Ixodes scapularis Deer tick  Isca\ISCW017817 Y Ixodes scapularis Deer tick  Isca\ISCW011576 Y Ixodes scapularis Deer tick  Isca\ISCW024407 Y Ixodes scapularis Deer tick  Isca\ISCW001782 Y Ixodes scapularis Deer tick  Isca\ISCW009309 Y Ixodes scapularis Deer tick  Isca\ISCW002826 Y Ixodes scapularis Deer tick  Isca\ISCW002955 Y Ixodes scapularis Deer tick  Isca\ISCW016309 Y Ixodes scapularis Deer tick  Isca\ISCW013218 Y Ixodes scapularis Deer tick  Isca\ISCW016307 Y Ixodes scapularis Deer tick  Isca\ISCW016296 Y Ixodes scapularis Deer tick  Isca\ISCW003783 Y Ixodes scapularis Deer tick  Isca\ISCW010522 Y
Orthologs in non-Arthropod Metazoa (None identified)
No non-Arthropod Metazoa orthologies identified
Human Orthologs (0)
Gene OMIM HGNC
AAA Orthologs (9) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD13279 Drosophila sechellia Dsec\GM13998 Drosophila erecta Dere\GG14206 Drosophila yakuba Dyak\GE20635 Drosophila ananassae Dana\GF23876 Drosophila pseudoobscura pseudoobscura Dpse\GA28204 Drosophila willistoni Dwil\GK10237 Drosophila mojavensis Dmoj\GI14579 Drosophila grimshawi Dgri\GH15545
Stocks & Reagents
Stocks Listed in FlyBase ( 2 )
VDRC	v105517 P{KK113267}VIE-260B v7486 w1118; P{GD2295}v7486
Genomic Clones ( 2 )
	BACR39O11 BACR48M07 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 7 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	IP04416
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones
Other clones	81763 CK01.32C.C12 CK01.77D.D10 CK01.84B.H7 EK027844 EK068832
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0035511 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 38509
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of	Source for identity of: Cpr64Ab CG15007 (Willis, 2007.1.3)
Source for database merge of
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_139616 RefSeq (Proteins) • NP_647873 DDBJ / EMBL / GenBank • AAF47862 Entrez Gene - A searchable database of RefSeq genes. • 38509 UniProtKB/TrEMBL • Q9VZG1
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Insect cuticle protein (IPR000618)
Linkouts
	DroID - A comprehensive database of gene and protein interactions. • FBgn0035511 DRSC - Results from RNAi screens. • FBgn0035511 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0035511 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG15007-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0035511 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 38509 modMine - Data generated by the modENCODE project. • FBgn0035511
Synonyms & Secondary IDs ( 4 )
Reported As
Symbol Synonym	CG15007 (Willis, 2007.1.3, Karouzou et al., 2007, Karouzou et al., 2007, Keleman et al., 2009.8.5, Haussmann et al., 2008, Cammarato et al., 2011) Cpr64Ab (Willis, 2007.1.3, Karouzou et al., 2007, Karouzou et al., 2007, Cornman and Willis, 2008, Cherbas et al., 2011) DmelCpr64Ab (Karouzou et al., 2007)
Name Synonym	CG15007   Cuticular protein 64Ab (Cammarato et al., 2011)
Secondary FlyBase IDs
References ( 17 )
Research paper	Cherbas et al., 2011, Genome Res. 21(2): 301--314 The transcriptional diversity of 25 Drosophila cell lines. [FBrf0213077] Cornman and Willis, 2008, Insect Biochem. Mol. Biol. 38(6): 661--676 Extensive gene amplification and concerted evolution within the CPR family of cuticular proteins in mosquitoes. [FBrf0206399] Haussmann et al., 2008, Genome Biol. 9(4): R73 Erect wing regulates synaptic growth in Drosophila by integration of multiple signaling pathways. [FBrf0209726]
Supplementary material	Cammarato et al., 2011, PLoS ONE 6(4): Table S1. Proteins & Peptides. [FBrf0214682] Graveley et al., 2011, Nature 471(7339): Supplementary Table 33. Fuzzy Cluster Members. [FBrf0213980] The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518] Karouzou et al., 2007, Insect Biochem. Mol. Biol. 37(8): Table S1. [FBrf0200185] Karouzou et al., 2007, Insect Biochem. Mol. Biol. 37(8): Tables S2-S5. [FBrf0200186]
Review	Karouzou et al., 2007, Insect Biochem. Mol. Biol. 37(8): 754--760 Drosophila cuticular proteins with the R&R Consensus: annotation and classification with a new tool for discriminating RR-1 and RR-2 sequences. [FBrf0200175]
Personal communication to FlyBase	Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] Willis, 2007.1.3, Drosophila genes that have the R&R consensus. Drosophila genes that have the R&R consensus. [FBrf0199281] Ryder, 2004.4.26, Exelixis CG deletion data. Exelixis CG deletion data. [FBrf0184335]
FlyBase analysis	FlyBase, 1992-, FlyBase curation. FlyBase curation. [FBrf0105495]
Curated genome annotation	Ashburner, 1999.11, [Annotations performed at the Celera Jamboreee.] [Annotations performed at the Celera Jamboreee.] [FBrf0126651] FamiliarityBreedsContempt, 1999.11, [Automatic annotations performed at the Celera Jamboreee.] [Automatic annotations performed at the Celera Jamboreee.] [FBrf0126705]