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Gene Dmel\CG11586

General Information
Symbol	Dmel\CG11586	Species	D. melanogaster
Name		Annotation symbol	CG11586
Feature type	protein_coding_gene	FlyBase ID	FBgn0035520
Gene Model Status	Current	Stock availability	5 publicly available
Genomic Location
Chromosome (arm)	3L	Recombination map
Cytogenetic map	64A12-64A12	Sequence location	3L:4,261,298..4,262,461 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG11586 (FBgn0035520). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function: zinc ion binding; nucleic acid binding. The biological processes in which it is involved are not known. 4 alleles are reported. The phenotypes of these alleles are annotated with: trichogen cell; mesothoracic tergum. It has one annotated transcript and one annotated polypeptide. Protein features are: Zinc finger, C2H2-like; Zinc finger, U1-type; Zinc finger, double-stranded RNA binding. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-12 hour embryonic stages. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult eye. Comments on Affy2 ProbeSet: ProbeSet 1630952_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG11586. Gene sequence location is 3L:4261298..4262461.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2012_01	Sequence features BKN27848 HFA08203
FB2011_10
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 64A12-64A12   Limits computationally determined from genome sequence between P{PZ}l(3)rG166rG166 and P{PZ}sinu06524
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG11586 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG11586-RA FBtr0073243  NM_139624   1105   194
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG11586-PA   FBpp0073099   22.9   194   9.76     NP_647881   AAF47873
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Zinc finger, C2H2-like (IPR015880) Zinc finger, U1-type (IPR003604) Zinc finger, double-stranded RNA binding (IPR022755)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA949303   AE014296 AAF47873   AI107611   AI512742   AW943737   AY061480 AAL29028   BE975589   BI212814   BT125921   CK662139   CO314539   EC248713   EV579606   GH739850   GH742265   GH744354   GH744386   GH744645   GH744792   GH744931   GH746367   GH746516   GH746688   GH762899   GH763439   GH763480   GH764606   GH766072   GH766722   GH767275   GH769106   GH769184   GH769428
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9VZF0
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0035520    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0035520 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-12 hour embryonic stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0035520 expression level Developmental Stage   Expression Level embryo 00-02hr    3335 embryo 02-04hr    4545 embryo 04-06hr    4155 embryo 06-08hr    4081 embryo 08-10hr    3850 embryo 10-12hr    3538 embryo 12-14hr    2245 embryo 14-16hr    1974 embryo 16-18hr    1548 embryo 18-20hr    1064 embryo 20-22hr    1323 embryo 22-24hr    1223 larva L1    937 larva L2    949 larva L3 12hr old    701 larva L3 puffstage 1-2    1074 larva L3 puffstage 3-6    1420 larva L3 puffstage 7-9    1732 white prepupae new    1753 white prepupae 12hr    1828 white prepupae 24hr    2151 pupae 2d postWPP    1911 pupae 3d postWPP    1436 pupae 4d postWPP    1001 adult male 01day    1376 adult male 05day    1707 adult male 30day    1513 adult female 01day    1347 adult female 05day    2031 adult female 30day    2176 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (3335) embryo 02-04hr  (4545) embryo 04-06hr  (4155) embryo 06-08hr  (4081) embryo 08-10hr  (3850) embryo 10-12hr  (3538) embryo 12-14hr  (2245) embryo 14-16hr  (1974) embryo 16-18hr  (1548) embryo 18-20hr  (1064) embryo 20-22hr  (1323) embryo 22-24hr  (1223) larva L1  (937) larva L2  (949) larva L3 12hr old  (701) larva L3 puffstage 1-2  (1074) larva L3 puffstage 3-6  (1420) larva L3 puffstage 7-9  (1732) white prepupae new  (1753) white prepupae 12hr  (1828) white prepupae 24hr  (2151) pupae 2d postWPP  (1911) pupae 3d postWPP  (1436) pupae 4d postWPP  (1001) adult male 01day  (1376) adult male 05day  (1707) adult male 30day  (1513) adult female 01day  (1347) adult female 05day  (2031) adult female 30day  (2176) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (3335) embryo 02-04hr  (4545) embryo 04-06hr  (4155) embryo 06-08hr  (4081) embryo 08-10hr  (3850) embryo 10-12hr  (3538) embryo 12-14hr  (2245) embryo 14-16hr  (1974) embryo 16-18hr  (1548) embryo 18-20hr    1064 embryo 20-22hr    1323 embryo 22-24hr    1223 larva L1    937 larva L2    949 larva L3 12hr old    701 larva L3 puffstage 1-2    1074 larva L3 puffstage 3-6  1420 larva L3 puffstage 7-9  (1732) white prepupae new  (1753) white prepupae 12hr  (1828) white prepupae 24hr  (2151) pupae 2d postWPP  (1911) pupae 3d postWPP  1436 pupae 4d postWPP    1001 adult male 01day    1376 adult male 05day  (1707) adult male 30day  (1513) adult female 01day    1347 adult female 05day  (2031) adult female 30day  (2176) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    3335 embryo 02-04hr    4545 embryo 04-06hr    4155 embryo 06-08hr    4081 embryo 08-10hr    3850 embryo 10-12hr    3538 embryo 12-14hr    2245 embryo 14-16hr    1974 embryo 16-18hr    1548 embryo 18-20hr    1064 embryo 20-22hr    1323 embryo 22-24hr    1223 larva L1    937 larva L2    949 larva L3 12hr old    701 larva L3 puffstage 1-2    1074 larva L3 puffstage 3-6    1420 larva L3 puffstage 7-9    1732 white prepupae new    1753 white prepupae 12hr    1828 white prepupae 24hr    2151 pupae 2d postWPP    1911 pupae 3d postWPP    1436 pupae 4d postWPP    1001 adult male 01day    1376 adult male 05day    1707 adult male 30day    1513 adult female 01day    1347 adult female 05day    2031 adult female 30day    2176 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    3335 embryo 02-04hr    4545 embryo 04-06hr    4155 embryo 06-08hr    4081 embryo 08-10hr    3850 embryo 10-12hr    3538 embryo 12-14hr    2245 embryo 14-16hr    1974 embryo 16-18hr    1548 embryo 18-20hr    1064 embryo 20-22hr    1323 embryo 22-24hr    1223 larva L1    937 larva L2    949 larva L3 12hr old    701 larva L3 puffstage 1-2    1074 larva L3 puffstage 3-6    1420 larva L3 puffstage 7-9    1732 white prepupae new    1753 white prepupae 12hr    1828 white prepupae 24hr    2151 pupae 2d postWPP    1911 pupae 3d postWPP    1436 pupae 4d postWPP    1001 adult male 01day    1376 adult male 05day    1707 adult male 30day    1513 adult female 01day    1347 adult female 05day    2031 adult female 30day    2176 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0035520 expression level Developmental Stage   Expression Level embryo 00-02hr    3335 embryo 02-04hr    4545 embryo 04-06hr    4155 embryo 06-08hr    4081 embryo 08-10hr    3850 embryo 10-12hr    3538 embryo 12-14hr    2245 embryo 14-16hr    1974 embryo 16-18hr    1548 embryo 18-20hr    1064 embryo 20-22hr    1323 embryo 22-24hr    1223 larva L1    937 larva L2    949 larva L3 12hr old    701 larva L3 puffstage 1-2    1074 larva L3 puffstage 3-6    1420 larva L3 puffstage 7-9    1732 white prepupae new    1753 white prepupae 12hr    1828 white prepupae 24hr    2151 pupae 2d postWPP    1911 pupae 3d postWPP    1436 pupae 4d postWPP    1001 adult male 01day    1376 adult male 05day    1707 adult male 30day    1513 adult female 01day    1347 adult female 05day    2031 adult female 30day    2176 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (3335) embryo 02-04hr  (4545) embryo 04-06hr  (4155) embryo 06-08hr  (4081) embryo 08-10hr  (3850) embryo 10-12hr  (3538) embryo 12-14hr  (2245) embryo 14-16hr  (1974) embryo 16-18hr  (1548) embryo 18-20hr  (1064) embryo 20-22hr  (1323) embryo 22-24hr  (1223) larva L1  (937) larva L2  (949) larva L3 12hr old  (701) larva L3 puffstage 1-2  (1074) larva L3 puffstage 3-6  (1420) larva L3 puffstage 7-9  (1732) white prepupae new  (1753) white prepupae 12hr  (1828) white prepupae 24hr  (2151) pupae 2d postWPP  (1911) pupae 3d postWPP  (1436) pupae 4d postWPP  (1001) adult male 01day  (1376) adult male 05day  (1707) adult male 30day  (1513) adult female 01day  (1347) adult female 05day  (2031) adult female 30day  (2176) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (3335) embryo 02-04hr  (4545) embryo 04-06hr  (4155) embryo 06-08hr  (4081) embryo 08-10hr  (3850) embryo 10-12hr  (3538) embryo 12-14hr  2245 embryo 14-16hr  1974 embryo 16-18hr  1548 embryo 18-20hr    1064 embryo 20-22hr    1323 embryo 22-24hr    1223 larva L1    937 larva L2    949 larva L3 12hr old    701 larva L3 puffstage 1-2    1074 larva L3 puffstage 3-6  1420 larva L3 puffstage 7-9  1732 white prepupae new  1753 white prepupae 12hr  1828 white prepupae 24hr  2151 pupae 2d postWPP  1911 pupae 3d postWPP  1436 pupae 4d postWPP    1001 adult male 01day    1376 adult male 05day  1707 adult male 30day  1513 adult female 01day    1347 adult female 05day  2031 adult female 30day  2176 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    3335 embryo 02-04hr    4545 embryo 04-06hr    4155 embryo 06-08hr    4081 embryo 08-10hr    3850 embryo 10-12hr    3538 embryo 12-14hr    2245 embryo 14-16hr    1974 embryo 16-18hr    1548 embryo 18-20hr    1064 embryo 20-22hr    1323 embryo 22-24hr    1223 larva L1    937 larva L2    949 larva L3 12hr old    701 larva L3 puffstage 1-2    1074 larva L3 puffstage 3-6    1420 larva L3 puffstage 7-9    1732 white prepupae new    1753 white prepupae 12hr    1828 white prepupae 24hr    2151 pupae 2d postWPP    1911 pupae 3d postWPP    1436 pupae 4d postWPP    1001 adult male 01day    1376 adult male 05day    1707 adult male 30day    1513 adult female 01day    1347 adult female 05day    2031 adult female 30day    2176 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    3335 embryo 02-04hr    4545 embryo 04-06hr    4155 embryo 06-08hr    4081 embryo 08-10hr    3850 embryo 10-12hr    3538 embryo 12-14hr    2245 embryo 14-16hr    1974 embryo 16-18hr    1548 embryo 18-20hr    1064 embryo 20-22hr    1323 embryo 22-24hr    1223 larva L1    937 larva L2    949 larva L3 12hr old    701 larva L3 puffstage 1-2    1074 larva L3 puffstage 3-6    1420 larva L3 puffstage 7-9    1732 white prepupae new    1753 white prepupae 12hr    1828 white prepupae 24hr    2151 pupae 2d postWPP    1911 pupae 3d postWPP    1436 pupae 4d postWPP    1001 adult male 01day    1376 adult male 05day    1707 adult male 30day    1513 adult female 01day    1347 adult female 05day    2031 adult female 30day    2176 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0035520    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0035520 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult eye. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0035520 expression level Tissue   Expression Level Larval Central Nervous System    94.1 Larval Midgut no informative data Larval Hindgut    50.6 Larval Malpighian Tubules    42.9 Larval Fat Body    47.7 Larval Salivary Gland    74.2 Larval Trachea    65.275 Larval Carcass    51.325 Adult Head    53.9 Adult Eye    215.8 Adult Brain    65.4 Adult Thoracic-Abdominal Ganglion    57.2 Adult Crop    55.4 Adult Midgut no informative data Adult Hindgut    36.4 Adult Malpighian Tubules    32.1 Adult Fat Body    48.8 Adult Salivary Gland    60.1 Adult Heart    54.875 Adult VirginFemale Spermatheca    54.1 Adult InseminatedFemale Spermatheca    62.3 Adult Ovary    93.3 Adult Testis    69.7 Adult Male Accessory Gland    50.6 Adult Carcass    53.4 Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    94.1 Larval Midgut no informative data Larval Hindgut    50.6 Larval Malpighian Tubules    42.9 Larval Fat Body    47.7 Larval Salivary Gland    74.2 Larval Trachea    65.275 Larval Carcass    51.325 Adult Head    53.9 Adult Eye    215.8 Adult Brain    65.4 Adult Thoracic-Abdominal Ganglion    57.2 Adult Crop    55.4 Adult Midgut no informative data Adult Hindgut    36.4 Adult Malpighian Tubules    32.1 Adult Fat Body    48.8 Adult Salivary Gland    60.1 Adult Heart    54.875 Adult VirginFemale Spermatheca    54.1 Adult InseminatedFemale Spermatheca    62.3 Adult Ovary    93.3 Adult Testis    69.7 Adult Male Accessory Gland    50.6 Adult Carcass    53.4 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    94.1 Larval Midgut no informative data Larval Hindgut    50.6 Larval Malpighian Tubules    42.9 Larval Fat Body    47.7 Larval Salivary Gland    74.2 Larval Trachea    65.275 Larval Carcass    51.325 Adult Head    53.9 Adult Eye    215.8 Adult Brain    65.4 Adult Thoracic-Abdominal Ganglion    57.2 Adult Crop    55.4 Adult Midgut no informative data Adult Hindgut    36.4 Adult Malpighian Tubules    32.1 Adult Fat Body    48.8 Adult Salivary Gland    60.1 Adult Heart    54.875 Adult VirginFemale Spermatheca    54.1 Adult InseminatedFemale Spermatheca    62.3 Adult Ovary    93.3 Adult Testis    69.7 Adult Male Accessory Gland    50.6 Adult Carcass    53.4 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    94.1 Larval Midgut no informative data Larval Hindgut    50.6 Larval Malpighian Tubules    42.9 Larval Fat Body    47.7 Larval Salivary Gland    74.2 Larval Trachea    65.275 Larval Carcass    51.325 Adult Head    53.9 Adult Eye    215.8 Adult Brain    65.4 Adult Thoracic-Abdominal Ganglion    57.2 Adult Crop    55.4 Adult Midgut no informative data Adult Hindgut    36.4 Adult Malpighian Tubules    32.1 Adult Fat Body    48.8 Adult Salivary Gland    60.1 Adult Heart    54.875 Adult VirginFemale Spermatheca    54.1 Adult InseminatedFemale Spermatheca    62.3 Adult Ovary    93.3 Adult Testis    69.7 Adult Male Accessory Gland    50.6 Adult Carcass    53.4 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0035520 expression level Tissue   Expression Level Larval Central Nervous System    94.1 Larval Midgut no informative data Larval Hindgut    50.6 Larval Malpighian Tubules    42.9 Larval Fat Body    47.7 Larval Salivary Gland    74.2 Larval Trachea    65.275 Larval Carcass    51.325 Adult Head    53.9 Adult Eye    215.8 Adult Brain    65.4 Adult Thoracic-Abdominal Ganglion    57.2 Adult Crop    55.4 Adult Midgut no informative data Adult Hindgut    36.4 Adult Malpighian Tubules    32.1 Adult Fat Body    48.8 Adult Salivary Gland    60.1 Adult Heart    54.875 Adult VirginFemale Spermatheca    54.1 Adult InseminatedFemale Spermatheca    62.3 Adult Ovary    93.3 Adult Testis    69.7 Adult Male Accessory Gland    50.6 Adult Carcass    53.4 Expression Level Scale  None   Low   Moderate  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    94.1 Larval Midgut no informative data Larval Hindgut    50.6 Larval Malpighian Tubules    42.9 Larval Fat Body    47.7 Larval Salivary Gland    74.2 Larval Trachea    65.275 Larval Carcass    51.325 Adult Head    53.9 Adult Eye    215.8 Adult Brain    65.4 Adult Thoracic-Abdominal Ganglion    57.2 Adult Crop    55.4 Adult Midgut no informative data Adult Hindgut    36.4 Adult Malpighian Tubules    32.1 Adult Fat Body    48.8 Adult Salivary Gland    60.1 Adult Heart    54.875 Adult VirginFemale Spermatheca    54.1 Adult InseminatedFemale Spermatheca    62.3 Adult Ovary    93.3 Adult Testis    69.7 Adult Male Accessory Gland    50.6 Adult Carcass    53.4 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    94.1 Larval Midgut no informative data Larval Hindgut    50.6 Larval Malpighian Tubules    42.9 Larval Fat Body    47.7 Larval Salivary Gland    74.2 Larval Trachea    65.275 Larval Carcass    51.325 Adult Head    53.9 Adult Eye    215.8 Adult Brain    65.4 Adult Thoracic-Abdominal Ganglion    57.2 Adult Crop    55.4 Adult Midgut no informative data Adult Hindgut    36.4 Adult Malpighian Tubules    32.1 Adult Fat Body    48.8 Adult Salivary Gland    60.1 Adult Heart    54.875 Adult VirginFemale Spermatheca    54.1 Adult InseminatedFemale Spermatheca    62.3 Adult Ovary    93.3 Adult Testis    69.7 Adult Male Accessory Gland    50.6 Adult Carcass    53.4 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    94.1 Larval Midgut no informative data Larval Hindgut    50.6 Larval Malpighian Tubules    42.9 Larval Fat Body    47.7 Larval Salivary Gland    74.2 Larval Trachea    65.275 Larval Carcass    51.325 Adult Head    53.9 Adult Eye    215.8 Adult Brain    65.4 Adult Thoracic-Abdominal Ganglion    57.2 Adult Crop    55.4 Adult Midgut no informative data Adult Hindgut    36.4 Adult Malpighian Tubules    32.1 Adult Fat Body    48.8 Adult Salivary Gland    60.1 Adult Heart    54.875 Adult VirginFemale Spermatheca    54.1 Adult InseminatedFemale Spermatheca    62.3 Adult Ovary    93.3 Adult Testis    69.7 Adult Male Accessory Gland    50.6 Adult Carcass    53.4 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut no informative data Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut no informative data Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    53.9   NA  Eye    215.8   NA  Brain    65.4   94.1  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    57.2   NA  Crop    55.4   no informative data  Midgut    no informative data   50.6  Hindgut    36.4   42.9  Malpighian Tubules    32.1   47.7  Fat Body    48.8   74.2  Salivary Gland    60.1   NA  Heart    54.875   65.275  Trachea    NA   NA  VirginFemale Spermatheca    54.1   NA  InseminatedFemale Spermatheca    62.3   NA  Ovary    93.3   NA  Testis    69.7   NA  Male Accessory Gland    50.6   51.325  Carcass    53.4 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_30
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0035520 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG11586-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele semi-lethal | pupal stage, with Scer\GAL4pnr-MD237 CG11586GD7337 Other Phenotypes Allele visible, with Scer\GAL4pnr-MD237 CG11586GD7337 Phenotype manifest in Allele mesothoracic tergum, with Scer\GAL4pnr-MD237 CG11586GD7337 trichogen cell, with Scer\GAL4pnr-MD237 CG11586GD7337
Classical Alleles ( 2 )
For All Classical Alleles Show
Allele of CG11586 Class Mutagen Stocks Known lesion CG11586G19133 P-element activity 1 -- CG11586MI01616 1 --
Alleles Carried on Transgenic Constructs ( 2 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG11586 Class Mutagen Stocks Known lesion CG11586GD7337 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes CG11586KK107848 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes
Aneuploid Aberrations
Disrupted in	Df(3L)Exel8098 (Ryder, 2004.4.26) Df(3L)Exel9000 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD7337} NA P{KK107848} NA
Insertions
	Type of insertions Name Expression data insertion of mobile activating element P{EP}CG11586G19133 NA miscellaneous insertions Mi{MIC}CG11586MI01616 NA
Gene Ontology: Function, Process & Cellular Component ( 3 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 3 terms )
Molecular Function
CV term Evidence References
nucleic acid binding inferred from electronic annotation with InterPro:IPR003604 (FlyBase Curators et al., 2004-) zinc ion binding inferred from electronic annotation with InterPro:IPR003604, InterPro:IPR015880 (FlyBase Curators et al., 2004-)
Biological Process ( 0 terms)
Cellular Component
CV term Evidence References
intracellular inferred from electronic annotation with InterPro:IPR015880 (FlyBase Curators et al., 2004-)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG11586 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 63998 DroID - A comprehensive database of gene and protein interactions. • FBgn0035520 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 38520
Orthologs
Genome-wide drosophilid orthologs	Dana\GF24743 Dere\GG14201 Dgri\GH15537 Dmoj\GI16814 Dper\GL12725 Dpse\GA11083 Dsec\GM13992 Dsim\GD13271 Dvir\GJ12561 Dwil\GK10568 Dyak\GE20629
Curated drosophilid orthologs	Dpse\GA11083
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL001945-PA Aedes aegypti (mosquito) AGAP006245-PA Anopheles gambiae (mosquito) XP_624220.2 Apis mellifera (honey bee) XP_001943233.1 Acyrthosiphon pisum (pea aphid) At3g05760.1 Arabidopsis thaliana (wall cress) 88943 Batrachochytrium dendrobatidis (chytrid fungus) 128715 Branchiostoma floridae (lancelet) 128722 Branchiostoma floridae (lancelet) XP_001894211.1 Brugia malayi (roundworm nematode) BGIBMGA000360-PA Bombyx mori (silk worm) ENSBTAP00000007159 Bos taurus (bovine) CAL0005511 Candida albicans (a form of yeast) CN25208 Caenorhabditis brenneri (small nematode) CN27911 Caenorhabditis brenneri (small nematode) CBP25045 Caenorhabditis briggsae (nematode) CE40676 Caenorhabditis elegans (worm) ENSCAFP00000008845 Canis familiaris (dog) CAGL0L07260g Candida glabrata (haploid yeast) Chro.30137 Cryptosporidium hominis (obligate parasite) ENSCINP00000002580 Ciona intestinalis (sea squirt) JA09067 Caenorhabditis japonica (nematode) cn12021 Cryptococcus neoformans (yeast-like fungus) cgd3_1060 Cryptosporidium parvum (protozoan parasite) CPIJ009914 Culex pipens (mosquito) ENSCPOP00000008273 Cavia porcellus (guinea pig) 162439 Chlamidomonas reinhardtii (green alga) RP44094 Caenorhabditis remanei (nematode) ENSCSAVP00000014040 Ciona savignyi (sedentary tunicate) 20763 Capitella spl (polychaete worm) DDB0216436 Dictyostelium discoideum (amoeba) DEHA2B07480g Debaryomyces Hansenii (yeast) 301542 Daphnia pulex (daphnia) ENSDARP00000002108 Danio rerio (zebra fish) ENSECAP00000012050 Equus caballus (horse) XP_653187 Entamoeba histolytica (anaerobic protozoan) ENSGACP00000027626 Gymnopilus aculeatus (mushroom) ENSGALP00000001109 Gallus gallus (chicken) 162523 Hypsipyla robusta (cedar shoot borer) ENSP00000274712 Homo sapiens (human) ISCW010148-PA Ixodes scapularis (deer tick) KLLA0E01409g Kluyveromyces lactis (yeast) 228476 Lottia gigantea (owl limpet) 33398 Monocosta brevicollis (choanoflagellate) ENSMODP00000014114 Monodelphis domestica (gray opossum) ENSMMUP00000005976 Macaca mulatta (rhesus monkey) ENSMUSP00000001419 Mus musculus (house mouse) 165407 Nematostella vectensis (starlet anemone) XP_001599252.1 Nasonia vitripennis (wasp) ENSOANP00000011479 Ornithorynchus anatinus (platypus) ENSORLP00000000911 Oryzias latipes (japanese killifish) LOC_Os03g61640.1 Oryza sativa (asian rice) 32329 Ostreococcus tauri (green alga) PFL2075c Plasmodium falciparum (protozoal parasite) PHUM004629-PA Pediculus humanus (human body louse) PP04309 Pristionchus pacificus (nematode) 193667 Physcomitrella patens (moss) ENSPPYP00000017746 Pongo pygmaeus (orangutan) 77701 Phytophthora ramorum (sudden oak death pathogen) 158437 Phytophthora sojae (root rot pathogen) 729449 Populus trichocarpa (black cottonwood) ENSPTRP00000029620 Pan troglodytes (chimpanzee) PVX_101055 Plasmodium vivax (protozoal parasite) ENSRNOP00000021516 Rattus norvegicus (norway rat) 4750874 Sorghum bicolor (sorghum) YDL098C Saccharomyces cerevisiae (budding yeast) Smp_095680 Schistosoma mansoni (trematode parasite) 59979 Trichoplax adhaerens (metazoa) TA08155 Theileria annulata (apicomplexan parasite) XP_967938.1 Tribolium castaneum (red flour beetle) ENSTNIP00000010413 Tetraodon nigroviridis (green spotted pufferfish) TP04_0385 Theileria parva (parasitic protozoan) 11166 Thalassiosira pseudonana (marine diatom) ENSTRUP00000020671 Takifugu rubripes (pufferfish Takifugu) 3707.m00172 Tetrahymena thermophila (ciliate protozoa) ENSXETP00000035148 Xenopus tropicalis (frog) YALI0F09361g Yarrowia lipolytica (nonconventional yeast) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB11627 NV50290 NV16226 LH18811 ISCW010148 FBgn0237934 FBgn0212583 FBgn0199801 FBgn0184991 FBgn0168921 JGI_V11_301542 FBgn0071138 FBgn0150331 FBgn0139561 FBgn0123009 FBgn0106462 FBgn0101736 CPIJ009914 BGIBMGA000360 ACYPI009162 GB16932 AGAP006245 AAEL001945 PHUM117550 GLEAN_16272
Stocks & Reagents
Stocks Listed in FlyBase ( 5 )
Bloomington	29677 y1 w*; P{EP}CG11586G19133 34223 y1 w*; Mi{MIC}CG11586MI01616 CG1309MI01616/TM3, Sb1 Ser1
VDRC	v104359 P{KK107848}VIE-260B v31531 w1118; P{GD7337}v31531/TM3 v31532 w1118; P{GD7337}v31532/CyO
Genomic Clones ( 2 )
	BACR39O11 BACR48M07 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 31 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	LD44732
Other clones	DPiM_LD44732 MIP29039
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	GH05382 LD28145 LP22138 RE18053
Other clones	117675 bs44b01 Dmel_dig_008417_0682_1564 EK236850 RP001006153 RP001007299 RP001009009 RP001012203 RP001013183 RP001013427 RP001015041 RP001018075 RP001018557 RP001021607 RP001021949 RP001026633 RP001031471 RP001032076 RP001039605 RP001044781 RP001047641 RP001051537 RP001052551 RP001055194
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0035520 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 38520
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_139624 RefSeq (Proteins) • NP_647881 DDBJ / EMBL / GenBank • AAF47873 AAL29028 AI512742 AW943737 AY061480 Entrez Gene - A searchable database of RefSeq genes. • 38520 UniProtKB/TrEMBL • Q9VZF0
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Zinc finger, C2H2-like (IPR015880) Zinc finger, U1-type (IPR003604) Zinc finger, double-stranded RNA binding (IPR022755)
Linkouts
	BioGRID - A database of protein and genetic interactions • 63998 DroID - A comprehensive database of gene and protein interactions. • FBgn0035520 DRSC - Results from RNAi screens. • FBgn0035520 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0035520 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG11586-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0035520 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 38520 InParanoid A subset of ortholog calls from InParanoid. • AAEL001945-PA Aedes aegypti (mosquito) AGAP006245-PA Anopheles gambiae (mosquito) XP_624220.2 Apis mellifera (honey bee) XP_001943233.1 Acyrthosiphon pisum (pea aphid) At3g05760.1 Arabidopsis thaliana (wall cress) 88943 Batrachochytrium dendrobatidis (chytrid fungus) 128715 Branchiostoma floridae (lancelet) 128722 Branchiostoma floridae (lancelet) XP_001894211.1 Brugia malayi (roundworm nematode) BGIBMGA000360-PA Bombyx mori (silk worm) ENSBTAP00000007159 Bos taurus (bovine) CAL0005511 Candida albicans (a form of yeast) CN25208 Caenorhabditis brenneri (small nematode) CN27911 Caenorhabditis brenneri (small nematode) CBP25045 Caenorhabditis briggsae (nematode) CE40676 Caenorhabditis elegans (worm) ENSCAFP00000008845 Canis familiaris (dog) CAGL0L07260g Candida glabrata (haploid yeast) Chro.30137 Cryptosporidium hominis (obligate parasite) ENSCINP00000002580 Ciona intestinalis (sea squirt) JA09067 Caenorhabditis japonica (nematode) cn12021 Cryptococcus neoformans (yeast-like fungus) cgd3_1060 Cryptosporidium parvum (protozoan parasite) CPIJ009914 Culex pipens (mosquito) ENSCPOP00000008273 Cavia porcellus (guinea pig) 162439 Chlamidomonas reinhardtii (green alga) RP44094 Caenorhabditis remanei (nematode) ENSCSAVP00000014040 Ciona savignyi (sedentary tunicate) 20763 Capitella spl (polychaete worm) DDB0216436 Dictyostelium discoideum (amoeba) DEHA2B07480g Debaryomyces Hansenii (yeast) 301542 Daphnia pulex (daphnia) ENSDARP00000002108 Danio rerio (zebra fish) ENSECAP00000012050 Equus caballus (horse) XP_653187 Entamoeba histolytica (anaerobic protozoan) ENSGACP00000027626 Gymnopilus aculeatus (mushroom) ENSGALP00000001109 Gallus gallus (chicken) 162523 Hypsipyla robusta (cedar shoot borer) ENSP00000274712 Homo sapiens (human) ISCW010148-PA Ixodes scapularis (deer tick) KLLA0E01409g Kluyveromyces lactis (yeast) 228476 Lottia gigantea (owl limpet) 33398 Monocosta brevicollis (choanoflagellate) ENSMODP00000014114 Monodelphis domestica (gray opossum) ENSMMUP00000005976 Macaca mulatta (rhesus monkey) ENSMUSP00000001419 Mus musculus (house mouse) 165407 Nematostella vectensis (starlet anemone) XP_001599252.1 Nasonia vitripennis (wasp) ENSOANP00000011479 Ornithorynchus anatinus (platypus) ENSORLP00000000911 Oryzias latipes (japanese killifish) LOC_Os03g61640.1 Oryza sativa (asian rice) 32329 Ostreococcus tauri (green alga) PFL2075c Plasmodium falciparum (protozoal parasite) PHUM004629-PA Pediculus humanus (human body louse) PP04309 Pristionchus pacificus (nematode) 193667 Physcomitrella patens (moss) ENSPPYP00000017746 Pongo pygmaeus (orangutan) 77701 Phytophthora ramorum (sudden oak death pathogen) 158437 Phytophthora sojae (root rot pathogen) 729449 Populus trichocarpa (black cottonwood) ENSPTRP00000029620 Pan troglodytes (chimpanzee) PVX_101055 Plasmodium vivax (protozoal parasite) ENSRNOP00000021516 Rattus norvegicus (norway rat) 4750874 Sorghum bicolor (sorghum) YDL098C Saccharomyces cerevisiae (budding yeast) Smp_095680 Schistosoma mansoni (trematode parasite) 59979 Trichoplax adhaerens (metazoa) TA08155 Theileria annulata (apicomplexan parasite) XP_967938.1 Tribolium castaneum (red flour beetle) ENSTNIP00000010413 Tetraodon nigroviridis (green spotted pufferfish) TP04_0385 Theileria parva (parasitic protozoan) 11166 Thalassiosira pseudonana (marine diatom) ENSTRUP00000020671 Takifugu rubripes (pufferfish Takifugu) 3707.m00172 Tetrahymena thermophila (ciliate protozoa) ENSXETP00000035148 Xenopus tropicalis (frog) YALI0F09361g Yarrowia lipolytica (nonconventional yeast) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 38520 modMine - Data generated by the modENCODE project. • FBgn0035520 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB11627 NV50290 NV16226 LH18811 ISCW010148 FBgn0237934 FBgn0212583 FBgn0199801 FBgn0184991 FBgn0168921 JGI_V11_301542 FBgn0071138 FBgn0150331 FBgn0139561 FBgn0123009 FBgn0106462 FBgn0101736 CPIJ009914 BGIBMGA000360 ACYPI009162 GB16932 AGAP006245 AAEL001945 PHUM117550 GLEAN_16272
Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	CG11586 (Keleman et al., 2009.8.5)
Name Synonym
Secondary FlyBase IDs
References ( 13 )
Research paper	Page et al., 2005, EMBO J. 24(24): 4304--4315 Spotted-dick, a zinc-finger protein of Drosophila required for expression of Orc4 and S phase. [FBrf0190363] Brody et al., 2002, Mech. Dev. 113(1): 41--59 Identification of novel Drosophila neural precursor genes using a differential embryonic head cDNA screen. [FBrf0147137]
Supplementary material	The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518] Giot et al., 2003, Science 302(5651): Tables S1 to S7. [FBrf0166452]
Personal communication to FlyBase	Bellen, 2011.1.31, set919.xml set919.xml [FBrf0212923] Bellen, 2009.12.18, BDGP_2009_1221.GenExel.xml BDGP_2009_1221.GenExel.xml [FBrf0209716] Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] FlyBase Curators et al., 2004-, Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. [FBrf0174215] Ryder, 2004.4.26, Exelixis CG deletion data. Exelixis CG deletion data. [FBrf0184335]
Computer file	BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. Berkeley Drosophila Genome Project. [FBrf0125078]