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Gene Dmel\CG15020

General Information
Symbol	Dmel\CG15020	Species	D. melanogaster
Name		Annotation symbol	CG15020
Feature type	protein_coding_gene	FlyBase ID	FBgn0035543
Gene Model Status	Current	Stock availability	2 publicly available
Genomic Location
Chromosome (arm)	3L	Recombination map
Cytogenetic map	64B5-64B6	Sequence location	3L:4,421,662..4,426,621 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG15020 (FBgn0035543). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: structural constituent of chitin-based cuticle. Based on sequence similarity, it is predicted to be involved in the biological process: cell morphogenesis. 4 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Zona pellucida domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of no expression detected. Peak expression observed within 12-24 hour embryonic stages, during late pupal stages. Summary of FlyAtlas Anatomical Expression Data: Little or no expression detected in any larval or adult organs/tissues. Comments on Affy2 ProbeSet: ProbeSet 1640853_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG15020. Gene sequence location is 3L:4421662..4426621.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 64B5-64B6   Limits computationally determined from genome sequence between P{PZ}l(3)rG166rG166 and P{PZ}sinu06524
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG15020 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.46
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG15020-RA FBtr0073298  NM_139644   2744   604
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG15020-PA   FBpp0073154   67.3   604   7.36     NP_647901   AAF47899
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Zona pellucida domain (IPR001507)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE014296 AAF47899   BT100191   CO266686   CO338936   CZ466815   EC244948   EC259967   EW713148   EW713202   FL502426
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9VZC5
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Little or no expression detected in any larval or adult organs/tissues. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    1.6 Larval Midgut    3.6 Larval Hindgut    1.7 Larval Malpighian Tubules    4.6 Larval Fat Body    4.3 Larval Salivary Gland    2.5 Larval Trachea    1.325 Larval Carcass    2.2 Adult Head    1.7 Adult Eye    22.425 Adult Brain    2.1 Adult Thoracic-Abdominal Ganglion    2.7 Adult Crop    2.9 Adult Midgut    2.4 Adult Hindgut    2.7 Adult Malpighian Tubules    2.7 Adult Fat Body    5.8 Adult Salivary Gland    9.4 Adult Heart    3.6 Adult VirginFemale Spermatheca    1.6 Adult InseminatedFemale Spermatheca    2.8 Adult Ovary    2.1 Adult Testis    3.7 Adult Male Accessory Gland    3.3 Adult Carcass    8.2 Expression Level Scale  None   Low  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    1.6 Larval Midgut    3.6 Larval Hindgut    1.7 Larval Malpighian Tubules    4.6 Larval Fat Body    4.3 Larval Salivary Gland    2.5 Larval Trachea    1.325 Larval Carcass    2.2 Adult Head    1.7 Adult Eye    22.425 Adult Brain    2.1 Adult Thoracic-Abdominal Ganglion    2.7 Adult Crop    2.9 Adult Midgut    2.4 Adult Hindgut    2.7 Adult Malpighian Tubules    2.7 Adult Fat Body    5.8 Adult Salivary Gland    9.4 Adult Heart    3.6 Adult VirginFemale Spermatheca    1.6 Adult InseminatedFemale Spermatheca    2.8 Adult Ovary    2.1 Adult Testis    3.7 Adult Male Accessory Gland    3.3 Adult Carcass    8.2 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    1.6 Larval Midgut    3.6 Larval Hindgut    1.7 Larval Malpighian Tubules    4.6 Larval Fat Body    4.3 Larval Salivary Gland    2.5 Larval Trachea    1.325 Larval Carcass    2.2 Adult Head    1.7 Adult Eye    22.425 Adult Brain    2.1 Adult Thoracic-Abdominal Ganglion    2.7 Adult Crop    2.9 Adult Midgut    2.4 Adult Hindgut    2.7 Adult Malpighian Tubules    2.7 Adult Fat Body    5.8 Adult Salivary Gland    9.4 Adult Heart    3.6 Adult VirginFemale Spermatheca    1.6 Adult InseminatedFemale Spermatheca    2.8 Adult Ovary    2.1 Adult Testis    3.7 Adult Male Accessory Gland    3.3 Adult Carcass    8.2 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    1.6 Larval Midgut    3.6 Larval Hindgut    1.7 Larval Malpighian Tubules    4.6 Larval Fat Body    4.3 Larval Salivary Gland    2.5 Larval Trachea    1.325 Larval Carcass    2.2 Adult Head    1.7 Adult Eye    22.425 Adult Brain    2.1 Adult Thoracic-Abdominal Ganglion    2.7 Adult Crop    2.9 Adult Midgut    2.4 Adult Hindgut    2.7 Adult Malpighian Tubules    2.7 Adult Fat Body    5.8 Adult Salivary Gland    9.4 Adult Heart    3.6 Adult VirginFemale Spermatheca    1.6 Adult InseminatedFemale Spermatheca    2.8 Adult Ovary    2.1 Adult Testis    3.7 Adult Male Accessory Gland    3.3 Adult Carcass    8.2 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    1.6 Larval Midgut    3.6 Larval Hindgut    1.7 Larval Malpighian Tubules    4.6 Larval Fat Body    4.3 Larval Salivary Gland    2.5 Larval Trachea    1.325 Larval Carcass    2.2 Adult Head    1.7 Adult Eye    22.425 Adult Brain    2.1 Adult Thoracic-Abdominal Ganglion    2.7 Adult Crop    2.9 Adult Midgut    2.4 Adult Hindgut    2.7 Adult Malpighian Tubules    2.7 Adult Fat Body    5.8 Adult Salivary Gland    9.4 Adult Heart    3.6 Adult VirginFemale Spermatheca    1.6 Adult InseminatedFemale Spermatheca    2.8 Adult Ovary    2.1 Adult Testis    3.7 Adult Male Accessory Gland    3.3 Adult Carcass    8.2 Expression Level Scale  None   Low  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    1.6 Larval Midgut    3.6 Larval Hindgut    1.7 Larval Malpighian Tubules    4.6 Larval Fat Body    4.3 Larval Salivary Gland    2.5 Larval Trachea    1.325 Larval Carcass    2.2 Adult Head    1.7 Adult Eye    22.425 Adult Brain    2.1 Adult Thoracic-Abdominal Ganglion    2.7 Adult Crop    2.9 Adult Midgut    2.4 Adult Hindgut    2.7 Adult Malpighian Tubules    2.7 Adult Fat Body    5.8 Adult Salivary Gland    9.4 Adult Heart    3.6 Adult VirginFemale Spermatheca    1.6 Adult InseminatedFemale Spermatheca    2.8 Adult Ovary    2.1 Adult Testis    3.7 Adult Male Accessory Gland    3.3 Adult Carcass    8.2 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    1.6 Larval Midgut    3.6 Larval Hindgut    1.7 Larval Malpighian Tubules    4.6 Larval Fat Body    4.3 Larval Salivary Gland    2.5 Larval Trachea    1.325 Larval Carcass    2.2 Adult Head    1.7 Adult Eye    22.425 Adult Brain    2.1 Adult Thoracic-Abdominal Ganglion    2.7 Adult Crop    2.9 Adult Midgut    2.4 Adult Hindgut    2.7 Adult Malpighian Tubules    2.7 Adult Fat Body    5.8 Adult Salivary Gland    9.4 Adult Heart    3.6 Adult VirginFemale Spermatheca    1.6 Adult InseminatedFemale Spermatheca    2.8 Adult Ovary    2.1 Adult Testis    3.7 Adult Male Accessory Gland    3.3 Adult Carcass    8.2 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    1.6 Larval Midgut    3.6 Larval Hindgut    1.7 Larval Malpighian Tubules    4.6 Larval Fat Body    4.3 Larval Salivary Gland    2.5 Larval Trachea    1.325 Larval Carcass    2.2 Adult Head    1.7 Adult Eye    22.425 Adult Brain    2.1 Adult Thoracic-Abdominal Ganglion    2.7 Adult Crop    2.9 Adult Midgut    2.4 Adult Hindgut    2.7 Adult Malpighian Tubules    2.7 Adult Fat Body    5.8 Adult Salivary Gland    9.4 Adult Heart    3.6 Adult VirginFemale Spermatheca    1.6 Adult InseminatedFemale Spermatheca    2.8 Adult Ovary    2.1 Adult Testis    3.7 Adult Male Accessory Gland    3.3 Adult Carcass    8.2 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    1.7   NA  Eye    22.425   NA  Brain    2.1   1.6  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    2.7   NA  Crop    2.9   3.6  Midgut    2.4   1.7  Hindgut    2.7   4.6  Malpighian Tubules    2.7   4.3  Fat Body    5.8   2.5  Salivary Gland    9.4   NA  Heart    3.6   1.325  Trachea    NA   NA  VirginFemale Spermatheca    1.6   NA  InseminatedFemale Spermatheca    2.8   NA  Ovary    2.1   NA  Testis    3.7   NA  Male Accessory Gland    3.3   2.2  Carcass    8.2 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of no expression detected. Peak expression observed within 12-24 hour embryonic stages, during late pupal stages. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    0 embryo 12-14hr    0 embryo 14-16hr    1 embryo 16-18hr    7 embryo 18-20hr    9 embryo 20-22hr    2 embryo 22-24hr    3 larva L1    0 larva L2    1 larva L3 12hr old    0 larva L3 puffstage 1-2    0 larva L3 puffstage 3-6    0 larva L3 puffstage 7-9    0 white prepupae new    0 white prepupae 12hr    0 white prepupae 24hr    0 pupae 2d postWPP    0 pupae 3d postWPP    6 pupae 4d postWPP    1 adult male 01day    0 adult male 05day    0 adult male 30day    0 adult female 01day    0 adult female 05day    0 adult female 30day    0 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    0 embryo 12-14hr    0 embryo 14-16hr    1 embryo 16-18hr    7 embryo 18-20hr    9 embryo 20-22hr    2 embryo 22-24hr    3 larva L1    0 larva L2    1 larva L3 12hr old    0 larva L3 puffstage 1-2    0 larva L3 puffstage 3-6    0 larva L3 puffstage 7-9    0 white prepupae new    0 white prepupae 12hr    0 white prepupae 24hr    0 pupae 2d postWPP    0 pupae 3d postWPP    6 pupae 4d postWPP    1 adult male 01day    0 adult male 05day    0 adult male 30day    0 adult female 01day    0 adult female 05day    0 adult female 30day    0 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    0 embryo 12-14hr    0 embryo 14-16hr    1 embryo 16-18hr    7 embryo 18-20hr    9 embryo 20-22hr    2 embryo 22-24hr    3 larva L1    0 larva L2    1 larva L3 12hr old    0 larva L3 puffstage 1-2    0 larva L3 puffstage 3-6    0 larva L3 puffstage 7-9    0 white prepupae new    0 white prepupae 12hr    0 white prepupae 24hr    0 pupae 2d postWPP    0 pupae 3d postWPP    6 pupae 4d postWPP    1 adult male 01day    0 adult male 05day    0 adult male 30day    0 adult female 01day    0 adult female 05day    0 adult female 30day    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    0 embryo 12-14hr    0 embryo 14-16hr    1 embryo 16-18hr    7 embryo 18-20hr    9 embryo 20-22hr    2 embryo 22-24hr    3 larva L1    0 larva L2    1 larva L3 12hr old    0 larva L3 puffstage 1-2    0 larva L3 puffstage 3-6    0 larva L3 puffstage 7-9    0 white prepupae new    0 white prepupae 12hr    0 white prepupae 24hr    0 pupae 2d postWPP    0 pupae 3d postWPP    6 pupae 4d postWPP    1 adult male 01day    0 adult male 05day    0 adult male 30day    0 adult female 01day    0 adult female 05day    0 adult female 30day    0 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    0 embryo 12-14hr    0 embryo 14-16hr    1 embryo 16-18hr    7 embryo 18-20hr    9 embryo 20-22hr    2 embryo 22-24hr    3 larva L1    0 larva L2    1 larva L3 12hr old    0 larva L3 puffstage 1-2    0 larva L3 puffstage 3-6    0 larva L3 puffstage 7-9    0 white prepupae new    0 white prepupae 12hr    0 white prepupae 24hr    0 pupae 2d postWPP    0 pupae 3d postWPP    6 pupae 4d postWPP    1 adult male 01day    0 adult male 05day    0 adult male 30day    0 adult female 01day    0 adult female 05day    0 adult female 30day    0 Expression Level Scale  Very low   Low   Moderate  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    0 embryo 12-14hr    0 embryo 14-16hr    1 embryo 16-18hr    7 embryo 18-20hr    9 embryo 20-22hr    2 embryo 22-24hr    3 larva L1    0 larva L2    1 larva L3 12hr old    0 larva L3 puffstage 1-2    0 larva L3 puffstage 3-6    0 larva L3 puffstage 7-9    0 white prepupae new    0 white prepupae 12hr    0 white prepupae 24hr    0 pupae 2d postWPP    0 pupae 3d postWPP    6 pupae 4d postWPP    1 adult male 01day    0 adult male 05day    0 adult male 30day    0 adult female 01day    0 adult female 05day    0 adult female 30day    0 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    0 embryo 12-14hr    0 embryo 14-16hr    1 embryo 16-18hr    7 embryo 18-20hr    9 embryo 20-22hr    2 embryo 22-24hr    3 larva L1    0 larva L2    1 larva L3 12hr old    0 larva L3 puffstage 1-2    0 larva L3 puffstage 3-6    0 larva L3 puffstage 7-9    0 white prepupae new    0 white prepupae 12hr    0 white prepupae 24hr    0 pupae 2d postWPP    0 pupae 3d postWPP    6 pupae 4d postWPP    1 adult male 01day    0 adult male 05day    0 adult male 30day    0 adult female 01day    0 adult female 05day    0 adult female 30day    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    0 embryo 12-14hr    0 embryo 14-16hr    1 embryo 16-18hr    7 embryo 18-20hr    9 embryo 20-22hr    2 embryo 22-24hr    3 larva L1    0 larva L2    1 larva L3 12hr old    0 larva L3 puffstage 1-2    0 larva L3 puffstage 3-6    0 larva L3 puffstage 7-9    0 white prepupae new    0 white prepupae 12hr    0 white prepupae 24hr    0 pupae 2d postWPP    0 pupae 3d postWPP    6 pupae 4d postWPP    1 adult male 01day    0 adult male 05day    0 adult male 30day    0 adult female 01day    0 adult female 05day    0 adult female 30day    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Treatments RNA-Seq
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_12 mE1_20_mRNA_expression_cluster_13
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0035543 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG15020-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable CG15020c01022 viable, with Scer\GAL4pnr-MD237 CG15020GD2304 Sterility Allele fertile CG15020c01022 Phenotype manifest in Allele
Classical Alleles ( 2 )
For All Classical Alleles Show
Allele of CG15020 Class Mutagen Stocks Known lesion CG15020MI07102 1 -- CG15020c01022 piggyBac transposase 0 --
Alleles Carried on Transgenic Constructs ( 2 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG15020 Class Mutagen Stocks Known lesion CG15020KK106861 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG15020GD2304 in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(3L)Exel6101 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD2304} NA P{KK106861} NA
Insertions
	Type of insertions Name Expression data miscellaneous insertions Mi{MIC}CG15020MI07102 NA PBac{PB}CG15020c01022 NA
Gene Ontology: Function, Process & Cellular Component ( 3 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 3 terms )
Molecular Function
CV term Evidence References
structural constituent of chitin-based cuticle inferred from sequence or structural similarity with dy (DiBartolomeis et al., 2002)
Biological Process
CV term Evidence References
cell morphogenesis inferred from sequence or structural similarity with dyl (Fernandes et al., 2010)
Cellular Component
CV term Evidence References
integral to membrane inferred from sequence model (Fernandes et al., 2010)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG15020 allele Gene References
External Data
Linkouts	DroID - A comprehensive database of gene and protein interactions. • FBgn0035543
Orthologs
OrthoDB Orthologs (47) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6256C9 Dipteran inclusive ortholog search EOG6FN4S9 Insect inclusive ortholog search EOG6CNPM9 Arthropod inclusive ortholog search EOG61VHJ4 Metazoa inclusive ortholog search EOG65F8GX
Orthologs in Drosophila Species (EOG6256C9)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\CG15020     Drosophila simulans   Dsim\GD13844 Y   Drosophila sechellia   Dsec\GM14659 Y   Drosophila erecta   Dere\GG15228 Y   Drosophila yakuba   Dyak\GE21447 Y   Drosophila ananassae   Dana\GF25071 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA13439 Y   Drosophila persimilis   Dper\GL17896 Y   Drosophila willistoni   Dwil\GK16582 Y   Drosophila virilis   Dvir\GJ12714 Y   Drosophila mojavensis   Dmoj\GI12727 Y   Drosophila grimshawi   Dgri\GH15681 Y
Orthologs in non-Drosophila Dipterans (EOG6FN4S9)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL013149   Aedes aegypti Yellow fever mosquito  Aaeg\AAEL003724   Anopheles gambiae Malaria mosquito  Agam\AGAP006705   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ005428
Orthologs in non-Dipteran Insects (EOG6CNPM9)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\GB55331   Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG006650   Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH18950   Atta cephalotes Leafcutter ant  Acep\ACEP27480   Atta cephalotes Leafcutter ant  Acep\ACEP27483   Camponotus floridanus Florida carpenter ant  Cflo\CFLO23291   Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL21481   Linepithema humile Argentine ant  Lhum\LH20843   Pogonomyrmex barbatus Red harvester ant  Pbar\PB15319   Solenopsis invicta Red fire ant  Sinv\SINV20614   Acyrthosiphon pisum Pea aphid  Apim\ACYPI003838   Pediculus humanus Human body louse  Phum\PHUM207310   Tribolium castaneum Red flour beetle  Tcas\TC010198
Orthologs in non-Insect Arthropods (EOG61VHJ4)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\Pbx1   Ixodes scapularis Deer tick  Isca\ISCW019811
Orthologs in non-Arthropod Metazoa (EOG65F8GX)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Caenorhabditis elegans Nematode  Cele\Y38C1AA.5 Y Caenorhabditis elegans Nematode  Cele\cutl-5 Y Caenorhabditis elegans Nematode  Cele\cutl-9 Y Caenorhabditis elegans Nematode  Cele\cutl-1 Y Caenorhabditis elegans Nematode  Cele\cut-3 Y Caenorhabditis elegans Nematode  Cele\cutl-3 Y Caenorhabditis elegans Nematode  Cele\cutl-7 Y Caenorhabditis elegans Nematode  Cele\cutl-2 Y Caenorhabditis elegans Nematode  Cele\cutl-20 Y Caenorhabditis elegans Nematode  Cele\cutl-14 Y Caenorhabditis elegans Nematode  Cele\cutl-4 Y Caenorhabditis elegans Nematode  Cele\cut-5 Y Caenorhabditis elegans Nematode  Cele\cut-4 Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_001968gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_012445gn Y Danio rerio Zebrafish  Drer\ENSDARG00000070224 Y
Human Orthologs (0)
Gene OMIM HGNC
AAA Orthologs (11) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD13844 Drosophila sechellia Dsec\GM14659 Drosophila erecta Dere\GG15228 Drosophila yakuba Dyak\GE21447 Drosophila ananassae Dana\GF25071 Drosophila pseudoobscura pseudoobscura Dpse\GA13439 Drosophila persimilis Dper\GL17896 Drosophila willistoni Dwil\GK16582 Drosophila virilis Dvir\GJ12714 Drosophila mojavensis Dmoj\GI12727 Drosophila grimshawi Dgri\GH15681
Stocks & Reagents
Stocks Listed in FlyBase ( 2 )
Bloomington	42205 y1 w*; Mi{MIC}CG15020MI07102
VDRC	v101086 P{KK106861}VIE-260B
Genomic Clones ( 2 )
	BACR05M07 BACR43N11 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 6 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones
Other clones	MIP13657
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones
Other clones	36502 214251.18 DMG4-chr3L.8.013.pred.a EK147230 EP00363
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0035543 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 38544
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_139644 RefSeq (Proteins) • NP_647901 DDBJ / EMBL / GenBank • AAF47899 CZ466815 Entrez Gene - A searchable database of RefSeq genes. • 38544 UniProtKB/TrEMBL • Q9VZC5
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Zona pellucida domain (IPR001507)
Linkouts
	DroID - A comprehensive database of gene and protein interactions. • FBgn0035543 DRSC - Results from RNAi screens. • FBgn0035543 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0035543 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG15020-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0035543 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 38544 modMine - Data generated by the modENCODE project. • FBgn0035543
Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	CG15020 (Lebo et al., 2009, Keleman et al., 2009.8.5, Fernandes et al., 2010)
Name Synonym
Secondary FlyBase IDs
References ( 17 )
Research paper	Fernandes et al., 2010, Dev. Cell 18(1): 64--76 Zona pellucida domain proteins remodel the apical compartment for localized cell shape changes. [FBrf0211093] Lebo et al., 2009, BMC Genomics 10: 80 Somatic, germline and sex hierarchy regulated gene expression during Drosophila metamorphosis. [FBrf0207472] Jazwinska and Affolter, 2004, Gene Expr. Patterns 4(4): 413--421 A family of genes encoding zona pellucida (ZP) domain proteins is expressed in various epithelial tissues during Drosophila embryogenesis. [FBrf0179263] DiBartolomeis et al., 2002, Mol. Genet. Genomics 267(5): 564--576 Molecular analysis of the Drosophila miniature-dusky ( m-dy) gene complex: m-dy mRNAs encode transmembrane proteins with similarity to C. elegans cuticulin. [FBrf0151697]
Supplementary material	Graveley et al., 2011, Nature 471(7339): Supplementary Table 33. Fuzzy Cluster Members. [FBrf0213980] The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518] Dietzl et al., 2007, Nature 448(7150): Supplementary Table 1. [FBrf0202579]
Personal communication to FlyBase	Bellen, 2012.10.23, set1006_v2.xml set1006_v2.xml [FBrf0219849] Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510] Gene Disruption Project members and Exelixis, 2005, Genomic mapping of Exelixis insertion collection. (Computer file) Genomic mapping of Exelixis insertion collection. (Computer file) [FBrf0184340] Bloomington Drosophila Stock Center, 2004.11.6, Exelixis insertion alleles that are not in FlyBase. Exelixis insertion alleles that are not in FlyBase. [FBrf0179797] Ryder, 2004.4.26, Exelixis CG deletion data. Exelixis CG deletion data. [FBrf0184335] Gene Disruption Project members, 2001-, (Computer file) (Computer file) [FBrf0132177]
FlyBase analysis	FlyBase, 1992-, FlyBase curation. FlyBase curation. [FBrf0105495]
Curated genome annotation	FamiliarityBreedsContempt, 1999.11, [Automatic annotations performed at the Celera Jamboreee.] [Automatic annotations performed at the Celera Jamboreee.] [FBrf0126705]