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Gene Dmel\Ir64a

General Information
Symbol	Dmel\Ir64a	Species	D. melanogaster
Name	Ionotropic receptor 64a	Annotation symbol	CG10633
Feature type	protein_coding_gene	FlyBase ID	FBgn0035604
Gene Model Status	Current	Stock availability	3 publicly available
Genomic Location
Chromosome (arm)	3L	Recombination map
Cytogenetic map	64C15-64C15	Sequence location	3L:5,371,886..5,375,921 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene Ionotropic receptor 64a is referred to in FlyBase by the symbol Dmel\Ir64a (CG10633, FBgn0035604). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: extracellular-glutamate-gated ion channel activity; ligand-gated ion channel activity. There is experimental evidence that it is involved in the biological process: detection of chemical stimulus involved in sensory perception; cellular response to acid. 6 alleles are reported. The phenotype of these alleles is annotated with: antennal lobe glomerulus DP1m. It has one annotated transcript and one annotated polypeptide. Protein features are: Ionotropic glutamate receptor. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very low expression to a trough of no expression detected. Peak expression observed in adult male stages. Summary of FlyAtlas Anatomical Expression Data: Little or no expression detected in any larval or adult organs/tissues. Comments on Affy2 ProbeSet: ProbeSet 1633636_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of Ir64a. Gene sequence location is 3L:5371886..5375921.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 64C15-64C15   Limits computationally determined from genome sequence between P{PZ}l(3)rG166rG166 and P{PZ}sinu06524
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\Ir64a for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.46
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) Ir64a-RA FBtr0077153  NM_139705   2580   859
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein Ir64a-PA   FBpp0076857   98.0   859   6.97     NP_647962   AAF50781
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Ionotropic glutamate receptor (IPR001320)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE014296 AAF50781
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9VRL4
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
in situ Stage Tissue/Position (including subcellular localization) Reference adult stage   sacculus | restricted   (Benton et al., 2009) Comment:neurons surrounding the third chamber of the sacculus neuron of sensillum coeloconicum of antennal segment 3   (Benton et al., 2009)
Additional Descriptive Data
	Ir64a transcript is observed in the neurons of the sensillum coeloconicum of antennal segment 3 that surround chamber III of the sacculus. (Benton et al., 2009)
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
sensory dendrite inferred from direct assay (Ai et al., 2010, Abuin et al., 2011)
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Little or no expression detected in any larval or adult organs/tissues. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    12.8 Larval Midgut    18.1 Larval Hindgut    9.2 Larval Malpighian Tubules    9.2 Larval Fat Body    6.1 Larval Salivary Gland    10.3 Larval Trachea    5.1 Larval Carcass    6.7 Adult Head    15.8 Adult Eye    5.1 Adult Brain    5 Adult Thoracic-Abdominal Ganglion    8.2 Adult Crop    9.8 Adult Midgut    21.7 Adult Hindgut    7.4 Adult Malpighian Tubules    14.3 Adult Fat Body    18.4 Adult Salivary Gland    27.5 Adult Heart    2.725 Adult VirginFemale Spermatheca    24 Adult InseminatedFemale Spermatheca    31.9 Adult Ovary    5.6 Adult Testis    6.2 Adult Male Accessory Gland    12.1 Adult Carcass    20 Expression Level Scale  None   Low  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    12.8 Larval Midgut    18.1 Larval Hindgut    9.2 Larval Malpighian Tubules    9.2 Larval Fat Body    6.1 Larval Salivary Gland    10.3 Larval Trachea    5.1 Larval Carcass    6.7 Adult Head    15.8 Adult Eye    5.1 Adult Brain    5 Adult Thoracic-Abdominal Ganglion    8.2 Adult Crop    9.8 Adult Midgut    21.7 Adult Hindgut    7.4 Adult Malpighian Tubules    14.3 Adult Fat Body    18.4 Adult Salivary Gland    27.5 Adult Heart    2.725 Adult VirginFemale Spermatheca    24 Adult InseminatedFemale Spermatheca    31.9 Adult Ovary    5.6 Adult Testis    6.2 Adult Male Accessory Gland    12.1 Adult Carcass    20 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    12.8 Larval Midgut    18.1 Larval Hindgut    9.2 Larval Malpighian Tubules    9.2 Larval Fat Body    6.1 Larval Salivary Gland    10.3 Larval Trachea    5.1 Larval Carcass    6.7 Adult Head    15.8 Adult Eye    5.1 Adult Brain    5 Adult Thoracic-Abdominal Ganglion    8.2 Adult Crop    9.8 Adult Midgut    21.7 Adult Hindgut    7.4 Adult Malpighian Tubules    14.3 Adult Fat Body    18.4 Adult Salivary Gland    27.5 Adult Heart    2.725 Adult VirginFemale Spermatheca    24 Adult InseminatedFemale Spermatheca    31.9 Adult Ovary    5.6 Adult Testis    6.2 Adult Male Accessory Gland    12.1 Adult Carcass    20 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    12.8 Larval Midgut    18.1 Larval Hindgut    9.2 Larval Malpighian Tubules    9.2 Larval Fat Body    6.1 Larval Salivary Gland    10.3 Larval Trachea    5.1 Larval Carcass    6.7 Adult Head    15.8 Adult Eye    5.1 Adult Brain    5 Adult Thoracic-Abdominal Ganglion    8.2 Adult Crop    9.8 Adult Midgut    21.7 Adult Hindgut    7.4 Adult Malpighian Tubules    14.3 Adult Fat Body    18.4 Adult Salivary Gland    27.5 Adult Heart    2.725 Adult VirginFemale Spermatheca    24 Adult InseminatedFemale Spermatheca    31.9 Adult Ovary    5.6 Adult Testis    6.2 Adult Male Accessory Gland    12.1 Adult Carcass    20 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    12.8 Larval Midgut    18.1 Larval Hindgut    9.2 Larval Malpighian Tubules    9.2 Larval Fat Body    6.1 Larval Salivary Gland    10.3 Larval Trachea    5.1 Larval Carcass    6.7 Adult Head    15.8 Adult Eye    5.1 Adult Brain    5 Adult Thoracic-Abdominal Ganglion    8.2 Adult Crop    9.8 Adult Midgut    21.7 Adult Hindgut    7.4 Adult Malpighian Tubules    14.3 Adult Fat Body    18.4 Adult Salivary Gland    27.5 Adult Heart    2.725 Adult VirginFemale Spermatheca    24 Adult InseminatedFemale Spermatheca    31.9 Adult Ovary    5.6 Adult Testis    6.2 Adult Male Accessory Gland    12.1 Adult Carcass    20 Expression Level Scale  None   Low  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    12.8 Larval Midgut    18.1 Larval Hindgut    9.2 Larval Malpighian Tubules    9.2 Larval Fat Body    6.1 Larval Salivary Gland    10.3 Larval Trachea    5.1 Larval Carcass    6.7 Adult Head    15.8 Adult Eye    5.1 Adult Brain    5 Adult Thoracic-Abdominal Ganglion    8.2 Adult Crop    9.8 Adult Midgut    21.7 Adult Hindgut    7.4 Adult Malpighian Tubules    14.3 Adult Fat Body    18.4 Adult Salivary Gland    27.5 Adult Heart    2.725 Adult VirginFemale Spermatheca    24 Adult InseminatedFemale Spermatheca    31.9 Adult Ovary    5.6 Adult Testis    6.2 Adult Male Accessory Gland    12.1 Adult Carcass    20 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    12.8 Larval Midgut    18.1 Larval Hindgut    9.2 Larval Malpighian Tubules    9.2 Larval Fat Body    6.1 Larval Salivary Gland    10.3 Larval Trachea    5.1 Larval Carcass    6.7 Adult Head    15.8 Adult Eye    5.1 Adult Brain    5 Adult Thoracic-Abdominal Ganglion    8.2 Adult Crop    9.8 Adult Midgut    21.7 Adult Hindgut    7.4 Adult Malpighian Tubules    14.3 Adult Fat Body    18.4 Adult Salivary Gland    27.5 Adult Heart    2.725 Adult VirginFemale Spermatheca    24 Adult InseminatedFemale Spermatheca    31.9 Adult Ovary    5.6 Adult Testis    6.2 Adult Male Accessory Gland    12.1 Adult Carcass    20 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    12.8 Larval Midgut    18.1 Larval Hindgut    9.2 Larval Malpighian Tubules    9.2 Larval Fat Body    6.1 Larval Salivary Gland    10.3 Larval Trachea    5.1 Larval Carcass    6.7 Adult Head    15.8 Adult Eye    5.1 Adult Brain    5 Adult Thoracic-Abdominal Ganglion    8.2 Adult Crop    9.8 Adult Midgut    21.7 Adult Hindgut    7.4 Adult Malpighian Tubules    14.3 Adult Fat Body    18.4 Adult Salivary Gland    27.5 Adult Heart    2.725 Adult VirginFemale Spermatheca    24 Adult InseminatedFemale Spermatheca    31.9 Adult Ovary    5.6 Adult Testis    6.2 Adult Male Accessory Gland    12.1 Adult Carcass    20 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    15.8   NA  Eye    5.1   NA  Brain    5   12.8  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    8.2   NA  Crop    9.8   no informative data  Midgut    no informative data   9.2  Hindgut    7.4   9.2  Malpighian Tubules    no informative data   6.1  Fat Body    18.4   no informative data  Salivary Gland    no informative data   NA  Heart    2.725   5.1  Trachea    NA   NA  VirginFemale Spermatheca    24   NA  InseminatedFemale Spermatheca    31.9   NA  Ovary    5.6   NA  Testis    6.2   NA  Male Accessory Gland    no informative data   6.7  Carcass    no informative data FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Treatments RNA-Seq
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (Graveley et al., 2011) mE1_20_mRNA_expression_cluster_08
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0035604 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG10633-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable, with Dcr-2Scer\UAS.cDa, Scer\GAL4e22c, Scer\GAL4sqh.PW Ir64aGD2314 viable, with Scer\GAL4pnr-MD237 Ir64aGD2314 Other Phenotypes Allele auditory perception defective | adult stage Ir64aMB05283 neurophysiology defective | recessive Ir64aMB05283 smell perception defective | recessive Ir64aMB05283 Phenotype manifest in Allele antennal lobe glomerulus DP1m Ir64aMB05283
Classical Alleles ( 2 )
For All Classical Alleles Show
Allele of Ir64a Class Mutagen Stocks Known lesion Ir64aMB05283 loss of function allele 1 -- Ir64arev1 mariner transposase 0 Yes
Alleles Carried on Transgenic Constructs ( 4 )
For All Alleles Carried on Transgenic Constructs Show
Allele of Ir64a Class Mutagen Stocks Known lesion Ir64aGD2314 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes Ir64aScer\UAS.cAa in vitro construct - regulatory fusion 1 Yes Ir64aScer\UAS.T:Hsap\CALR,T:Avic\GFP-EGFP in vitro construct - regulatory fusion in vitro construct - coding region fusion 0 Yes Ir64aT:Ivir\HA1 in vitro construct - coding region fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(3L)Exel6105 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{UAS-Ir64a.A} NA P{UAS-Ir64a.attB} NA GAL4 construct P{Ir64a-GAL4.A} No characterization construct P{Ir64a.HA} NA P{Ir64a-GAL80.A} NA
Insertions
	Type of insertions Name Expression data insertion of enhancer trap binary system Mi{ET1}Ir64aMB05283 No
Gene Ontology: Function, Process & Cellular Component ( 8 unique terms )
Terms Based on Experimental Evidence ( 3 terms )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
cellular response to acid inferred from mutant phenotype (Ai et al., 2010) detection of chemical stimulus involved in sensory perception inferred from expression pattern (Benton et al., 2009)
Cellular Component
CV term Evidence References
sensory dendrite inferred from direct assay (Ai et al., 2010, Abuin et al., 2011)
Terms Based on Predictions or Assertions ( 5 terms )
Molecular Function
CV term Evidence References
extracellular-glutamate-gated ion channel activity inferred from electronic annotation with InterPro:IPR001320 (FlyBase Curators et al., 2004-) inferred from sequence or structural similarity (Littleton and Ganetzky, 2000) ionotropic glutamate receptor activity inferred from electronic annotation with InterPro:IPR001320 (FlyBase Curators et al., 2004-) ligand-gated ion channel activity inferred from sequence model (Benton et al., 2009)
Biological Process ( 0 terms)
Cellular Component
CV term Evidence References
integral to membrane inferred from sequence model (Benton et al., 2009) membrane inferred from electronic annotation with InterPro:IPR001320 (FlyBase Curators et al., 2004-)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions Ir64a allele Gene References
External Data
Linkouts	DroID - A comprehensive database of gene and protein interactions. • FBgn0035604
Orthologs
OrthoDB Orthologs (20) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6XKVSB Dipteran inclusive ortholog search EOG6TF0T9 Insect inclusive ortholog search EOG6KSNG3 Arthropod inclusive ortholog search No orthologs identified Metazoa inclusive ortholog search No orthologs identified
Orthologs in Drosophila Species (EOG6XKVSB)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\Ir64a     Drosophila simulans   Dsim\GD13200 Y   Drosophila sechellia   Dsec\GM13920 Y   Drosophila erecta   Dere\GG14133 Y   Drosophila yakuba   Dyak\GE20562 Y   Drosophila ananassae   Dana\GF10464 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA10455 Y   Drosophila persimilis   Dper\GL12225 Y   Drosophila willistoni   Dwil\GK17317 Y   Drosophila virilis   Dvir\GJ13401 Y   Drosophila mojavensis   Dmoj\GI12129 Y   Drosophila grimshawi   Dgri\GH15192 Y
Orthologs in non-Drosophila Dipterans (EOG6TF0T9)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL010880   Anopheles gambiae Malaria mosquito  Agam\AGAP004923   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ009887
Orthologs in non-Dipteran Insects (EOG6KSNG3)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG013074   Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG013076   Acyrthosiphon pisum Pea aphid  Apim\ACYPI45178   Bombyx mori Silkmoth  Bmor\BGIBMGA010367   Tribolium castaneum Red flour beetle  Tcas\TC009986
Orthologs in non-Insect Arthropods (None identified)
No non-Insect Arthropod orthologies identified
Orthologs in non-Arthropod Metazoa (None identified)
No non-Arthropod Metazoa orthologies identified
Human Orthologs (0)
Gene OMIM HGNC
AAA Orthologs (11) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD13200 Drosophila sechellia Dsec\GM13920 Drosophila erecta Dere\GG14133 Drosophila yakuba Dyak\GE20562 Drosophila ananassae Dana\GF10464 Drosophila pseudoobscura pseudoobscura Dpse\GA10455 Drosophila persimilis Dper\GL12225 Drosophila willistoni Dwil\GK17317 Drosophila virilis Dvir\GJ13401 Drosophila mojavensis Dmoj\GI12129 Drosophila grimshawi Dgri\GH15192
Stocks & Reagents
Stocks Listed in FlyBase ( 3 )
Bloomington	24610 w1118; Mi{ET1}Ir64aMB05283 41746 w*; P{UAS-Ir64a.A}BT21.1; TM2/TM6B, Tb1
VDRC	v9011 w1118; P{GD2314}v9011
Genomic Clones ( 2 )
	BACR12P14 BACR47H05 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 0 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones
Other clones
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0035604 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 38616
Antibody Information
	polyclonal (Ai et al., 2010)
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of	Source for identity of: Ir64a CG10633 (Benton et al., 2009)
Source for database merge of
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_139705 RefSeq (Proteins) • NP_647962 DDBJ / EMBL / GenBank • AAF50781 Entrez Gene - A searchable database of RefSeq genes. • 38616 UniProtKB/TrEMBL • Q9VRL4
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Ionotropic glutamate receptor (IPR001320)
Linkouts
	DroID - A comprehensive database of gene and protein interactions. • FBgn0035604 DRSC - Results from RNAi screens. • FBgn0035604 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0035604 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG10633-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0035604 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 38616 modMine - Data generated by the modENCODE project. • FBgn0035604
Synonyms & Secondary IDs ( 7 )
Reported As
Symbol Synonym	CG10633 (Lee et al., 2009, Croset et al., 2010, Benton et al., 2009, Tsubouchi et al., 2012) CT29782 (Littleton and Ganetzky, 2000) DmelIR64a (Croset et al., 2010) IR64a (Silbering et al., 2011, Benton et al., 2009, Croset et al., 2010, Abuin et al., 2011, Ai et al., 2010, Ramdya et al., 2012) Ir64a (Tsubouchi et al., 2012, Senthilan et al., 2012)
Name Synonym	CG10633   ionotropic receptor 64a (Benton et al., 2009) Ionotropic receptor 64a (Tsubouchi et al., 2012)
Secondary FlyBase IDs
References ( 20 )
Research paper	Ramdya et al., 2012, PLoS ONE 7(11): e48381 Fluorescence Behavioral Imaging (FBI) Tracks Identity in Heterogeneous Groups of Drosophila. [FBrf0219924] Senthilan et al., 2012, Cell 150(5): 1042--1054 Drosophila auditory organ genes and genetic hearing defects. [FBrf0219321] Abuin et al., 2011, Neuron 69(1): 44--60 Functional architecture of olfactory ionotropic glutamate receptors. [FBrf0212725] Silbering et al., 2011, J. Neurosci. 31(38): 13357--13375 Complementary Function and Integrated Wiring of the Evolutionarily Distinct Drosophila Olfactory Subsystems. [FBrf0215822] Ai et al., 2010, Nature 468(7324): 691--695 Acid sensing by the Drosophila olfactory system. [FBrf0212455] Croset et al., 2010, PLoS Genet. 6(8): e1001064 Ancient protostome origin of chemosensory ionotropic glutamate receptors and the evolution of insect taste and olfaction. [FBrf0211681] Benton et al., 2009, Cell 136(1): 149--162 Variant ionotropic glutamate receptors as chemosensory receptors in Drosophila. [FBrf0206496] Lee et al., 2009, Comp. Biochem. Physiol. C. Toxicol. Pharmacol. 150(4): 546--557 Furthering pharmacological and physiological assessment of the glutamatergic receptors at the Drosophila neuromuscular junction. [FBrf0209026] Littleton and Ganetzky, 2000, Neuron 26(1): 35--43 Ion channels and synaptic organization: analysis of the Drosophila genome. [FBrf0127201]
Supplementary material	Tsubouchi et al., 2012, Curr. Biol. 22(22): Tables S1 and S2. RNAi Lines Tested for Screening and Candidate Channel Genes, Related to Figure 5. [FBrf0220657] Graveley et al., 2011, Nature 471(7339): Supplementary Table 33. Fuzzy Cluster Members. [FBrf0213980] Croset et al., 2010, PLoS Genet. 6(8): Supporting Information: Table S3. [FBrf0219605] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518]
Personal communication to FlyBase	Bellen, 2007.10.9, batch761.xml batch761.xml [FBrf0200260] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] FlyBase Curators et al., 2004-, Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. [FBrf0174215] Ryder, 2004.4.26, Exelixis CG deletion data. Exelixis CG deletion data. [FBrf0184335]
Curated genome annotation	FamiliarityBreedsContempt, 1999.11, [Automatic annotations performed at the Celera Jamboreee.] [Automatic annotations performed at the Celera Jamboreee.] [FBrf0126705] Ketchum, 1999.11, [Annotations performed at the Celera Jamboreee.] [Annotations performed at the Celera Jamboreee.] [FBrf0126677]
DNA/RNA sequence record	Thornton, 2005.12.20, GenBank/EMBL/DDBJ: DQ334058 Drosophila miranda CG10633 gene, partial cds. [FBrf0197667]