endopeptidase required for sister chromatid separation during mitosis - required for homolog and sister disjunction during male meiosis - together with Three rows it forms a complex which cleaves a subunit of the cohesin complex during meiosis
Gene model reviewed during 5.44
Gene model reviewed during 5.45
There is only one protein coding transcript and one polypeptide associated with this gene
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Sse using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\Sse in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
dsRNA directed against this gene has been used in a screen for genes required for constitutive protein secretion.
S2 cells treated with dsRNA generated against this gene show reduced phagocytosis of Candida albicans compared to untreated cells.
Candidate gene for tibia length quantitative trait locus.