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Gene Dmel\CG10467

General Information
Symbol	Dmel\CG10467	Species	D. melanogaster
Name		Annotation symbol	CG10467
Feature type	protein_coding_gene	FlyBase ID	FBgn0035679
Gene Model Status	Current	Stock availability	5 publicly available
Genomic Location
Chromosome (arm)	3L	Recombination map
Cytogenetic map	65A6-65A6	Sequence location	3L:6,086,304..6,087,836 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG10467 (FBgn0035679). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: aldose 1-epimerase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: hexose metabolic process. 6 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Aldose 1-epimerase; Aldose 1-epimerase, conserved site; Aldose 1-epimerase, subgroup; Glycoside hydrolase-type carbohydrate-binding; Glycoside hydrolase-type carbohydrate-binding, subgroup. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression. Peak expression observed during late larval stages, during early pupal stages. Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult organs/tissues expressed at moderate or high levels. Expression at high levels in the following post-embryonic organs or tissues: larval/adult midgut, adult hindgut, larval/adult Malpighian tubules, larval fat body, larval/adult salivary gland. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, adult crop, larval hindgut, adult heart, adult fat body, larval trachea, adult female reproductive system, adult male accessory gland, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1638020_at aligns to a genomic region shared by exons of 2 FlyBase-annotated genes; hence it is impossible to interpret the expression pattern and levels of CG10469 expression signal. See the GBrowse view of CG10469 to determine the overlapping gene(s). Gene sequence location is 3L:6086304..6087836.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2011_10	Controlled Vocabulary Terms day 42 of adulthood day 41 of adulthood day 30 of adulthood day 49 of adulthood day 17 of adulthood day 45 of adulthood day 8 of adulthood day 26 of adulthood day 21 of adulthood day 13 of adulthood day 25 of adulthood day 20 of adulthood day 22 of adulthood day 39 of adulthood day 7 of adulthood day 36 of adulthood day 11 of adulthood day 37 of adulthood day 27 of adulthood day 18 of adulthood day 19 of adulthood day 28 of adulthood day 9 of adulthood day 29 of adulthood adult heart day 40 of adulthood day 16 of adulthood day 24 of adulthood day 15 of adulthood day 33 of adulthood day 43 of adulthood day 47 of adulthood day 38 of adulthood day 32 of adulthood day 48 of adulthood day 23 of adulthood day 35 of adulthood day 12 of adulthood day 10 of adulthood day 31 of adulthood day 34 of adulthood day 44 of adulthood day 14 of adulthood day 46 of adulthood
FB2012_01	Sequence features HFA09728 BKN22810
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 65A6-65A6   Limits computationally determined from genome sequence between P{PZ}vn10567 and P{PZ}loj04026
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG10467 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG10467-RA FBtr0077063  NM_139769   1533   364
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG10467-PA   FBpp0076771   39.6   364   6.57     NP_648026   AAF50699
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Aldose 1-epimerase (IPR008183) Glycoside hydrolase-type carbohydrate-binding (IPR011013) Aldose 1-epimerase, conserved site (IPR018052) Glycoside hydrolase-type carbohydrate-binding, subgroup (IPR014718) Aldose 1-epimerase, subgroup (IPR015443)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE014296 AAF50699   AI297230   AY118414 AAM48443   BE978560   BI236290   BI238805   BI484766   BI580104   BI635863   BT057986   BT088877   CO193503   CO273928   CO277732   CO336162   CZ482814   CZ487173   EC051743   EC053257   EC083439   EC083980   EC261407   EL879202   EL879431   EL879556   ES688750   ES688758   ES688760   ES688773   ES688793   ES688795   ES688810   ES688822   ES688825   ES688859   ES688871   ES688877   ES688888   ES688903   ES688916   ES688953   ES688956   ES688963   ES688997   ES689000   ES689015   ES689018   ES689036   ES689039   ES689041   ES689049   ES689065   ES689080   ES689082   ES689085   ES689091   ES689093   ES689096   ES689104   ES689118   ES689123   ES689124   ES689125   ES689128   ES689135   ES689142   ES689162   ES689185   ES689186   ES689193   ES689568   ES689579   ES689580   ES689582   ES689592   ES689593   ES689595   ES689623   ES689627   ES689644   ES689647   ES689660   ES689661   ES689663   ES689674   ES689676   ES689678   ES689690   ES689693   ES689694   ES689696   ES689699   ES689700   ES689709   ES689713   ES689718   ES689722   ES689726   ES689731   ES689736   ES689737   ES689740   ES689745   ES689754   ES689757   ES689759   ES689772   ES689784   ES689785   ES689786   ES689787   ES689792   ES689804   ES689807   ES689810   ES689813   ES689814   ES689820   ES689824   ES689834   ES689841   ES689842   ES690804   ES690821   ES692564   ES692567   ES692574   ES692589   ES692593   ES692594   ES693590   ES693598   ES694136   ES694154   ES694167   ES694170   ES694234   ES694236   ES694240   EV596494   GH823425   GH855557   GH857559   GH863923   GH905807   GH924558
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q8MT28 Q9VRU1
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
mass spectroscopy Stage Tissue/Position (including subcellular localization) Reference day 7 of adulthood -- day 49 of adulthood   adult heart   (Cammarato et al., 2011)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0035679    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0035679 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression. Peak expression observed during late larval stages, during early pupal stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0035679 expression level Developmental Stage   Expression Level embryo 00-02hr    1020 embryo 02-04hr    930 embryo 04-06hr    902 embryo 06-08hr    650 embryo 08-10hr    524 embryo 10-12hr    353 embryo 12-14hr    278 embryo 14-16hr    304 embryo 16-18hr    301 embryo 18-20hr    260 embryo 20-22hr    148 embryo 22-24hr    190 larva L1    426 larva L2    778 larva L3 12hr old    1553 larva L3 puffstage 1-2    5063 larva L3 puffstage 3-6    3449 larva L3 puffstage 7-9    2949 white prepupae new    5107 white prepupae 12hr    2816 white prepupae 24hr    1329 pupae 2d postWPP    814 pupae 3d postWPP    546 pupae 4d postWPP    2614 adult male 01day    2477 adult male 05day    2027 adult male 30day    1729 adult female 01day    2490 adult female 05day    1558 adult female 30day    1411 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (1020) embryo 02-04hr  (930) embryo 04-06hr  (902) embryo 06-08hr  (650) embryo 08-10hr  (524) embryo 10-12hr  (353) embryo 12-14hr  (278) embryo 14-16hr  (304) embryo 16-18hr  (301) embryo 18-20hr  (260) embryo 20-22hr  (148) embryo 22-24hr  (190) larva L1  (426) larva L2  (778) larva L3 12hr old  (1553) larva L3 puffstage 1-2  (5063) larva L3 puffstage 3-6  (3449) larva L3 puffstage 7-9  (2949) white prepupae new  (5107) white prepupae 12hr  (2816) white prepupae 24hr  (1329) pupae 2d postWPP  (814) pupae 3d postWPP  (546) pupae 4d postWPP  (2614) adult male 01day  (2477) adult male 05day  (2027) adult male 30day  (1729) adult female 01day  (2490) adult female 05day  (1558) adult female 30day  (1411) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    1020 embryo 02-04hr    930 embryo 04-06hr    902 embryo 06-08hr    650 embryo 08-10hr    524 embryo 10-12hr    353 embryo 12-14hr    278 embryo 14-16hr    304 embryo 16-18hr    301 embryo 18-20hr    260 embryo 20-22hr    148 embryo 22-24hr    190 larva L1    426 larva L2    778 larva L3 12hr old  (1553) larva L3 puffstage 1-2  (5063) larva L3 puffstage 3-6  (3449) larva L3 puffstage 7-9  (2949) white prepupae new  (5107) white prepupae 12hr  (2816) white prepupae 24hr    1329 pupae 2d postWPP    814 pupae 3d postWPP    546 pupae 4d postWPP  (2614) adult male 01day  (2477) adult male 05day  (2027) adult male 30day  (1729) adult female 01day  (2490) adult female 05day  (1558) adult female 30day  1411 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    1020 embryo 02-04hr    930 embryo 04-06hr    902 embryo 06-08hr    650 embryo 08-10hr    524 embryo 10-12hr    353 embryo 12-14hr    278 embryo 14-16hr    304 embryo 16-18hr    301 embryo 18-20hr    260 embryo 20-22hr    148 embryo 22-24hr    190 larva L1    426 larva L2    778 larva L3 12hr old    1553 larva L3 puffstage 1-2    5063 larva L3 puffstage 3-6    3449 larva L3 puffstage 7-9    2949 white prepupae new    5107 white prepupae 12hr    2816 white prepupae 24hr    1329 pupae 2d postWPP    814 pupae 3d postWPP    546 pupae 4d postWPP    2614 adult male 01day    2477 adult male 05day    2027 adult male 30day    1729 adult female 01day    2490 adult female 05day    1558 adult female 30day    1411 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    1020 embryo 02-04hr    930 embryo 04-06hr    902 embryo 06-08hr    650 embryo 08-10hr    524 embryo 10-12hr    353 embryo 12-14hr    278 embryo 14-16hr    304 embryo 16-18hr    301 embryo 18-20hr    260 embryo 20-22hr    148 embryo 22-24hr    190 larva L1    426 larva L2    778 larva L3 12hr old    1553 larva L3 puffstage 1-2    5063 larva L3 puffstage 3-6    3449 larva L3 puffstage 7-9    2949 white prepupae new    5107 white prepupae 12hr    2816 white prepupae 24hr    1329 pupae 2d postWPP    814 pupae 3d postWPP    546 pupae 4d postWPP    2614 adult male 01day    2477 adult male 05day    2027 adult male 30day    1729 adult female 01day    2490 adult female 05day    1558 adult female 30day    1411 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0035679 expression level Developmental Stage   Expression Level embryo 00-02hr    1020 embryo 02-04hr    930 embryo 04-06hr    902 embryo 06-08hr    650 embryo 08-10hr    524 embryo 10-12hr    353 embryo 12-14hr    278 embryo 14-16hr    304 embryo 16-18hr    301 embryo 18-20hr    260 embryo 20-22hr    148 embryo 22-24hr    190 larva L1    426 larva L2    778 larva L3 12hr old    1553 larva L3 puffstage 1-2    5063 larva L3 puffstage 3-6    3449 larva L3 puffstage 7-9    2949 white prepupae new    5107 white prepupae 12hr    2816 white prepupae 24hr    1329 pupae 2d postWPP    814 pupae 3d postWPP    546 pupae 4d postWPP    2614 adult male 01day    2477 adult male 05day    2027 adult male 30day    1729 adult female 01day    2490 adult female 05day    1558 adult female 30day    1411 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (1020) embryo 02-04hr  (930) embryo 04-06hr  (902) embryo 06-08hr  (650) embryo 08-10hr  (524) embryo 10-12hr  (353) embryo 12-14hr  (278) embryo 14-16hr  (304) embryo 16-18hr  (301) embryo 18-20hr  (260) embryo 20-22hr  (148) embryo 22-24hr  (190) larva L1  (426) larva L2  (778) larva L3 12hr old  (1553) larva L3 puffstage 1-2  (5063) larva L3 puffstage 3-6  (3449) larva L3 puffstage 7-9  (2949) white prepupae new  (5107) white prepupae 12hr  (2816) white prepupae 24hr  (1329) pupae 2d postWPP  (814) pupae 3d postWPP  (546) pupae 4d postWPP  (2614) adult male 01day  (2477) adult male 05day  (2027) adult male 30day  (1729) adult female 01day  (2490) adult female 05day  (1558) adult female 30day  (1411) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    1020 embryo 02-04hr    930 embryo 04-06hr    902 embryo 06-08hr    650 embryo 08-10hr    524 embryo 10-12hr    353 embryo 12-14hr    278 embryo 14-16hr    304 embryo 16-18hr    301 embryo 18-20hr    260 embryo 20-22hr    148 embryo 22-24hr    190 larva L1    426 larva L2    778 larva L3 12hr old  1553 larva L3 puffstage 1-2  (5063) larva L3 puffstage 3-6  (3449) larva L3 puffstage 7-9  (2949) white prepupae new  (5107) white prepupae 12hr  (2816) white prepupae 24hr    1329 pupae 2d postWPP    814 pupae 3d postWPP    546 pupae 4d postWPP  (2614) adult male 01day  (2477) adult male 05day  2027 adult male 30day  1729 adult female 01day  (2490) adult female 05day  1558 adult female 30day  1411 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    1020 embryo 02-04hr    930 embryo 04-06hr    902 embryo 06-08hr    650 embryo 08-10hr    524 embryo 10-12hr    353 embryo 12-14hr    278 embryo 14-16hr    304 embryo 16-18hr    301 embryo 18-20hr    260 embryo 20-22hr    148 embryo 22-24hr    190 larva L1    426 larva L2    778 larva L3 12hr old    1553 larva L3 puffstage 1-2    5063 larva L3 puffstage 3-6    3449 larva L3 puffstage 7-9    2949 white prepupae new    5107 white prepupae 12hr    2816 white prepupae 24hr    1329 pupae 2d postWPP    814 pupae 3d postWPP    546 pupae 4d postWPP    2614 adult male 01day    2477 adult male 05day    2027 adult male 30day    1729 adult female 01day    2490 adult female 05day    1558 adult female 30day    1411 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    1020 embryo 02-04hr    930 embryo 04-06hr    902 embryo 06-08hr    650 embryo 08-10hr    524 embryo 10-12hr    353 embryo 12-14hr    278 embryo 14-16hr    304 embryo 16-18hr    301 embryo 18-20hr    260 embryo 20-22hr    148 embryo 22-24hr    190 larva L1    426 larva L2    778 larva L3 12hr old    1553 larva L3 puffstage 1-2    5063 larva L3 puffstage 3-6    3449 larva L3 puffstage 7-9    2949 white prepupae new    5107 white prepupae 12hr    2816 white prepupae 24hr    1329 pupae 2d postWPP    814 pupae 3d postWPP    546 pupae 4d postWPP    2614 adult male 01day    2477 adult male 05day    2027 adult male 30day    1729 adult female 01day    2490 adult female 05day    1558 adult female 30day    1411 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0035679    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0035679 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult organs/tissues expressed at moderate or high levels. Expression at high levels in the following post-embryonic organs or tissues: larval/adult midgut, adult hindgut, larval/adult Malpighian tubules, larval fat body, larval/adult salivary gland. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, adult crop, larval hindgut, adult heart, adult fat body, larval trachea, adult female reproductive system, adult male accessory gland, larval/adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0035679 expression level Tissue   Expression Level Larval Central Nervous System    68.325 Larval Midgut    519.2 Larval Hindgut    240.7 Larval Malpighian Tubules    4357 Larval Fat Body    894.7 Larval Salivary Gland    1038.2 Larval Trachea    195.15 Larval Carcass    307.6 Adult Head    147.9 Adult Eye    102.675 Adult Brain    63.5 Adult Thoracic-Abdominal Ganglion    66.4 Adult Crop    368.7 Adult Midgut    1659.6 Adult Hindgut    1171.6 Adult Malpighian Tubules    4059.4 Adult Fat Body    219.9 Adult Salivary Gland    694.1 Adult Heart    395.975 Adult VirginFemale Spermatheca    365 Adult InseminatedFemale Spermatheca    262.6 Adult Ovary    131.9 Adult Testis    24.7 Adult Male Accessory Gland    224.7 Adult Carcass    199.8 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    68.325 Larval Midgut  519.2 Larval Hindgut    240.7 Larval Malpighian Tubules  (4357) Larval Fat Body  (894.7) Larval Salivary Gland  (1038.2) Larval Trachea    195.15 Larval Carcass    307.6 Adult Head    147.9 Adult Eye    102.675 Adult Brain    63.5 Adult Thoracic-Abdominal Ganglion    66.4 Adult Crop    368.7 Adult Midgut  (1659.6) Adult Hindgut  (1171.6) Adult Malpighian Tubules  (4059.4) Adult Fat Body    219.9 Adult Salivary Gland  (694.1) Adult Heart    395.975 Adult VirginFemale Spermatheca    365 Adult InseminatedFemale Spermatheca    262.6 Adult Ovary    131.9 Adult Testis    24.7 Adult Male Accessory Gland    224.7 Adult Carcass    199.8 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    68.325 Larval Midgut    519.2 Larval Hindgut    240.7 Larval Malpighian Tubules  (4357) Larval Fat Body    894.7 Larval Salivary Gland  1038.2 Larval Trachea    195.15 Larval Carcass    307.6 Adult Head    147.9 Adult Eye    102.675 Adult Brain    63.5 Adult Thoracic-Abdominal Ganglion    66.4 Adult Crop    368.7 Adult Midgut  (1659.6) Adult Hindgut  (1171.6) Adult Malpighian Tubules  (4059.4) Adult Fat Body    219.9 Adult Salivary Gland    694.1 Adult Heart    395.975 Adult VirginFemale Spermatheca    365 Adult InseminatedFemale Spermatheca    262.6 Adult Ovary    131.9 Adult Testis    24.7 Adult Male Accessory Gland    224.7 Adult Carcass    199.8 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    68.325 Larval Midgut    519.2 Larval Hindgut    240.7 Larval Malpighian Tubules    4357 Larval Fat Body    894.7 Larval Salivary Gland    1038.2 Larval Trachea    195.15 Larval Carcass    307.6 Adult Head    147.9 Adult Eye    102.675 Adult Brain    63.5 Adult Thoracic-Abdominal Ganglion    66.4 Adult Crop    368.7 Adult Midgut    1659.6 Adult Hindgut    1171.6 Adult Malpighian Tubules    4059.4 Adult Fat Body    219.9 Adult Salivary Gland    694.1 Adult Heart    395.975 Adult VirginFemale Spermatheca    365 Adult InseminatedFemale Spermatheca    262.6 Adult Ovary    131.9 Adult Testis    24.7 Adult Male Accessory Gland    224.7 Adult Carcass    199.8 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0035679 expression level Tissue   Expression Level Larval Central Nervous System    68.325 Larval Midgut    519.2 Larval Hindgut    240.7 Larval Malpighian Tubules    4357 Larval Fat Body    894.7 Larval Salivary Gland    1038.2 Larval Trachea    195.15 Larval Carcass    307.6 Adult Head    147.9 Adult Eye    102.675 Adult Brain    63.5 Adult Thoracic-Abdominal Ganglion    66.4 Adult Crop    368.7 Adult Midgut    1659.6 Adult Hindgut    1171.6 Adult Malpighian Tubules    4059.4 Adult Fat Body    219.9 Adult Salivary Gland    694.1 Adult Heart    395.975 Adult VirginFemale Spermatheca    365 Adult InseminatedFemale Spermatheca    262.6 Adult Ovary    131.9 Adult Testis    24.7 Adult Male Accessory Gland    224.7 Adult Carcass    199.8 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    68.325 Larval Midgut  519.2 Larval Hindgut    240.7 Larval Malpighian Tubules  (4357) Larval Fat Body  (894.7) Larval Salivary Gland  (1038.2) Larval Trachea    195.15 Larval Carcass    307.6 Adult Head    147.9 Adult Eye    102.675 Adult Brain    63.5 Adult Thoracic-Abdominal Ganglion    66.4 Adult Crop    368.7 Adult Midgut  (1659.6) Adult Hindgut  (1171.6) Adult Malpighian Tubules  (4059.4) Adult Fat Body    219.9 Adult Salivary Gland  694.1 Adult Heart    395.975 Adult VirginFemale Spermatheca    365 Adult InseminatedFemale Spermatheca    262.6 Adult Ovary    131.9 Adult Testis    24.7 Adult Male Accessory Gland    224.7 Adult Carcass    199.8 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    68.325 Larval Midgut    519.2 Larval Hindgut    240.7 Larval Malpighian Tubules  (4357) Larval Fat Body    894.7 Larval Salivary Gland  1038.2 Larval Trachea    195.15 Larval Carcass    307.6 Adult Head    147.9 Adult Eye    102.675 Adult Brain    63.5 Adult Thoracic-Abdominal Ganglion    66.4 Adult Crop    368.7 Adult Midgut  1659.6 Adult Hindgut  1171.6 Adult Malpighian Tubules  (4059.4) Adult Fat Body    219.9 Adult Salivary Gland    694.1 Adult Heart    395.975 Adult VirginFemale Spermatheca    365 Adult InseminatedFemale Spermatheca    262.6 Adult Ovary    131.9 Adult Testis    24.7 Adult Male Accessory Gland    224.7 Adult Carcass    199.8 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    68.325 Larval Midgut    519.2 Larval Hindgut    240.7 Larval Malpighian Tubules    4357 Larval Fat Body    894.7 Larval Salivary Gland    1038.2 Larval Trachea    195.15 Larval Carcass    307.6 Adult Head    147.9 Adult Eye    102.675 Adult Brain    63.5 Adult Thoracic-Abdominal Ganglion    66.4 Adult Crop    368.7 Adult Midgut    1659.6 Adult Hindgut    1171.6 Adult Malpighian Tubules    4059.4 Adult Fat Body    219.9 Adult Salivary Gland    694.1 Adult Heart    395.975 Adult VirginFemale Spermatheca    365 Adult InseminatedFemale Spermatheca    262.6 Adult Ovary    131.9 Adult Testis    24.7 Adult Male Accessory Gland    224.7 Adult Carcass    199.8 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    147.9   NA  Eye    102.675   NA  Brain    63.5   68.325  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    66.4   NA  Crop    368.7   519.2  Midgut    1659.6   240.7  Hindgut    1171.6   4357  Malpighian Tubules    4059.4   894.7  Fat Body    219.9   1038.2  Salivary Gland    694.1   NA  Heart    395.975   195.15  Trachea    NA   NA  VirginFemale Spermatheca    365   NA  InseminatedFemale Spermatheca    262.6   NA  Ovary    131.9   NA  Testis    24.7   NA  Male Accessory Gland    224.7   307.6  Carcass    199.8 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_04
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0035679 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG10467-RA FlyExpress - Embryonic expression images (BDGP data) • Show all FlyExpress processed images for CG10467 Stages(s) 1-3 Stages(s) 4-6 Stages(s) 7-8 Stages(s) 9-10 Stages(s) 11-12 Stages(s) 13-16
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable, with Scer\GAL4pnr-MD237 CG10467GD6984 Phenotype manifest in Allele
Classical Alleles ( 4 )
For All Classical Alleles Show
Allele of CG10467 Class Mutagen Stocks Known lesion CG10467c02638 1 -- CG10467c06858a 1 -- CG10467f00348 piggyBac transposase 0 -- CG10467f04632 piggyBac transposase 0 --
Alleles Carried on Transgenic Constructs ( 2 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG10467 Class Mutagen Stocks Known lesion CG10467GD6984 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes CG10467KK102714 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes
Aneuploid Aberrations
Disrupted in	Df(3L)Exel8101 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD6984} NA P{KK102714} NA
Insertions
	Type of insertions Name Expression data miscellaneous insertions PBac{PB}CG10467c02638 NA PBac{PB}CG10467c06858a NA PBac{WH}CG10467f00348 NA PBac{WH}CG10467f04632 NA
Gene Ontology: Function, Process & Cellular Component ( 3 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 3 terms )
Molecular Function
CV term Evidence References
aldose 1-epimerase activity inferred from sequence or structural similarity with EMBL:AL049746 (FlyBase, 1992-) carbohydrate binding inferred from electronic annotation with InterPro:IPR011013, InterPro:IPR014718 (FlyBase Curators et al., 2004-)
Biological Process
CV term Evidence References
hexose metabolic process inferred from electronic annotation with InterPro:IPR015443 (FlyBase Curators et al., 2004-)
Cellular Component ( 0 terms)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG10467 allele Gene References
External Data
Linkouts	DroID - A comprehensive database of gene and protein interactions. • FBgn0035679 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 38697
Orthologs
Genome-wide drosophilid orthologs	Dana\GF10927 Dere\GG14088 Dgri\GH15657 Dmoj\GI12703 Dper\GL15523 Dpse\GA10332 Dsec\GM13871 Dsim\GD13155 Dvir\GJ12686 Dwil\GK16927 Dyak\GE20511
Curated drosophilid orthologs	Dpse\GA10332
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL010590-PA Aedes aegypti (mosquito) AGAP004376-PA Anopheles gambiae (mosquito) XP_624467.1 Apis mellifera (honey bee) At5g15140.1 Arabidopsis thaliana (wall cress) 132007 Branchiostoma floridae (lancelet) 284587 Branchiostoma floridae (lancelet) BGIBMGA009232-PA Bombyx mori (silk worm) ENSBTAP00000028111 Bos taurus (bovine) ENSCAFP00000009394 Canis familiaris (dog) CPIJ001655 Culex pipens (mosquito) ENSCPOP00000005886 Cavia porcellus (guinea pig) 187168 Chlamidomonas reinhardtii (green alga) ENSCSAVP00000014869 Ciona savignyi (sedentary tunicate) 221220 Capitella spl (polychaete worm) DEHA2D00902g Debaryomyces Hansenii (yeast) 99401 Daphnia pulex (daphnia) ENSDARP00000074789 Danio rerio (zebra fish) ENSECAP00000012291 Equus caballus (horse) XP_649046 Entamoeba histolytica (anaerobic protozoan) ENSGACP00000003256 Gymnopilus aculeatus (mushroom) ENSGALP00000022402 Gallus gallus (chicken) ENSP00000272252 Homo sapiens (human) KLLA0F08415g Kluyveromyces lactis (yeast) 236572 Lottia gigantea (owl limpet) LmjF23.0430 Leishmania major (virus) 8499 Monocosta brevicollis (choanoflagellate) ENSMODP00000010743 Monodelphis domestica (gray opossum) ENSMMUP00000014431 Macaca mulatta (rhesus monkey) ENSMUSP00000040580 Mus musculus (house mouse) 229971 Nematostella vectensis (starlet anemone) XP_001601223.1 Nasonia vitripennis (wasp) ENSORLP00000023979 Oryzias latipes (japanese killifish) LOC_Os10g06720.1 Oryza sativa (asian rice) 3943 Ostreococcus tauri (green alga) PHUM008940-PA Pediculus humanus (human body louse) PP20274 Pristionchus pacificus (nematode) 217391 Physcomitrella patens (moss) ENSPPYP00000013940 Pongo pygmaeus (orangutan) 71309 Phytophthora ramorum (sudden oak death pathogen) 756069 Populus trichocarpa (black cottonwood) ENSPTRP00000020344 Pan troglodytes (chimpanzee) ENSRNOP00000009221 Rattus norvegicus (norway rat) 143338 Sorghum bicolor (sorghum) 4742359 Sorghum bicolor (sorghum) XP_794587.2 Strongylocentrotus purpuratus (purple sea urchin) 28936 Trichoplax adhaerens (metazoa) XP_970690.2 Tribolium castaneum (red flour beetle) Tc00.1047053504425.90 Trypanosoma cruzi (parasitic trypanosome) Tc00.1047053509331.180 Trypanosoma cruzi (parasitic trypanosome) 15858 Thalassiosira pseudonana (marine diatom) 3721.m00084 Tetrahymena thermophila (ciliate protozoa) ENSXETP00000019772 Xenopus tropicalis (frog) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB16391 NV17196 LH20209 FBgn0237825 FBgn0218926 FBgn0199923 FBgn0184877 FBgn0168802 JGI_V11_99401 JGI_V11_60468 FBgn0070390 FBgn0153127 FBgn0135460 FBgn0123128 FBgn0106350 FBgn0087967 CPIJ001655 BGIBMGA012238 BGIBMGA009232 ACYPI43619 ACYPI007499 ACYPI003648 GB12384 AGAP004376 AAEL010590 PHUM366120 GLEAN_10337 GLEAN_01766
Stocks & Reagents
Stocks Listed in FlyBase ( 5 )
Harvard	- PBac{PB}CG10467c02638 - PBac{PB}CG10467c06858a, PBac{PB}c06858b, PBac{PB}c06858c
VDRC	v103787 P{KK102714}VIE-260B v27262 w1118; P{GD6984}v27262 v27263 w1118; P{GD6984}v27263/TM3
Genomic Clones ( 1 )
	BACR09G21 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 28 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	RE67917
Other clones	FI04403 MIP04215
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	LP11489 RE32330 RE41882 RE74241 SD17384
Other clones	11623 16046 557065 bs79c08 Dmel_neb_013535_0940_2642 EC36261 EC051743 EC053257 EK112649 EK126148 EN11953 IP09209 IP09409 IP09509 RP003075389 RP003095833 RP003105141 RP003188234 RP003269947 RP003355182
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0035679 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 38697
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_139769 RefSeq (Proteins) • NP_648026 DDBJ / EMBL / GenBank • AAF50699 AAM48443 AY118414 BI484766 CZ482814 CZ487173 Entrez Gene - A searchable database of RefSeq genes. • 38697 UniProtKB/TrEMBL • Q8MT28 Q9VRU1
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Aldose 1-epimerase (IPR008183) Glycoside hydrolase-type carbohydrate-binding (IPR011013) Aldose 1-epimerase, conserved site (IPR018052) Glycoside hydrolase-type carbohydrate-binding, subgroup (IPR014718) Aldose 1-epimerase, subgroup (IPR015443)
Linkouts
	DroID - A comprehensive database of gene and protein interactions. • FBgn0035679 DRSC - Results from RNAi screens. • FBgn0035679 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0035679 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG10467-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0035679 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 38697 InParanoid A subset of ortholog calls from InParanoid. • AAEL010590-PA Aedes aegypti (mosquito) AGAP004376-PA Anopheles gambiae (mosquito) XP_624467.1 Apis mellifera (honey bee) At5g15140.1 Arabidopsis thaliana (wall cress) 132007 Branchiostoma floridae (lancelet) 284587 Branchiostoma floridae (lancelet) BGIBMGA009232-PA Bombyx mori (silk worm) ENSBTAP00000028111 Bos taurus (bovine) ENSCAFP00000009394 Canis familiaris (dog) CPIJ001655 Culex pipens (mosquito) ENSCPOP00000005886 Cavia porcellus (guinea pig) 187168 Chlamidomonas reinhardtii (green alga) ENSCSAVP00000014869 Ciona savignyi (sedentary tunicate) 221220 Capitella spl (polychaete worm) DEHA2D00902g Debaryomyces Hansenii (yeast) 99401 Daphnia pulex (daphnia) ENSDARP00000074789 Danio rerio (zebra fish) ENSECAP00000012291 Equus caballus (horse) XP_649046 Entamoeba histolytica (anaerobic protozoan) ENSGACP00000003256 Gymnopilus aculeatus (mushroom) ENSGALP00000022402 Gallus gallus (chicken) ENSP00000272252 Homo sapiens (human) KLLA0F08415g Kluyveromyces lactis (yeast) 236572 Lottia gigantea (owl limpet) LmjF23.0430 Leishmania major (virus) 8499 Monocosta brevicollis (choanoflagellate) ENSMODP00000010743 Monodelphis domestica (gray opossum) ENSMMUP00000014431 Macaca mulatta (rhesus monkey) ENSMUSP00000040580 Mus musculus (house mouse) 229971 Nematostella vectensis (starlet anemone) XP_001601223.1 Nasonia vitripennis (wasp) ENSORLP00000023979 Oryzias latipes (japanese killifish) LOC_Os10g06720.1 Oryza sativa (asian rice) 3943 Ostreococcus tauri (green alga) PHUM008940-PA Pediculus humanus (human body louse) PP20274 Pristionchus pacificus (nematode) 217391 Physcomitrella patens (moss) ENSPPYP00000013940 Pongo pygmaeus (orangutan) 71309 Phytophthora ramorum (sudden oak death pathogen) 756069 Populus trichocarpa (black cottonwood) ENSPTRP00000020344 Pan troglodytes (chimpanzee) ENSRNOP00000009221 Rattus norvegicus (norway rat) 143338 Sorghum bicolor (sorghum) 4742359 Sorghum bicolor (sorghum) XP_794587.2 Strongylocentrotus purpuratus (purple sea urchin) 28936 Trichoplax adhaerens (metazoa) XP_970690.2 Tribolium castaneum (red flour beetle) Tc00.1047053504425.90 Trypanosoma cruzi (parasitic trypanosome) Tc00.1047053509331.180 Trypanosoma cruzi (parasitic trypanosome) 15858 Thalassiosira pseudonana (marine diatom) 3721.m00084 Tetrahymena thermophila (ciliate protozoa) ENSXETP00000019772 Xenopus tropicalis (frog) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 38697 modMine - Data generated by the modENCODE project. • FBgn0035679 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB16391 NV17196 LH20209 FBgn0237825 FBgn0218926 FBgn0199923 FBgn0184877 FBgn0168802 JGI_V11_99401 JGI_V11_60468 FBgn0070390 FBgn0153127 FBgn0135460 FBgn0123128 FBgn0106350 FBgn0087967 CPIJ001655 BGIBMGA012238 BGIBMGA009232 ACYPI43619 ACYPI007499 ACYPI003648 GB12384 AGAP004376 AAEL010590 PHUM366120 GLEAN_10337 GLEAN_01766
Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	CG10467 (Keleman et al., 2009.8.5, Cammarato et al., 2011)
Name Synonym
Secondary FlyBase IDs
References ( 19 )
Research paper	Karlsson et al., 2004, J. Biol. Chem. 279(50): 52033--52041 Proteomic analysis of the Drosophila larval hemolymph clot. [FBrf0180365] Pedra et al., 2004, Proc. Natl. Acad. Sci. USA 101(18): 7034--7039 Genome-wide transcription profile of field- and laboratory-selected dichlorodiphenyltrichloroethane (DDT)-resistant Drosophila. [FBrf0175100] Vierstraete et al., 2003, Biochem. biophys. Res. Commun. 304(4): 831--838 Proteomics in Drosophila melanogaster: first 2D database of larval hemolymph proteins. [FBrf0158736] Anholt and Mackay, 2001, Behav. Genet. 31(1): 17--27 The genetic architecture of odor-guided behavior in Drosophila melanogaster. [FBrf0138231]
Supplementary material	Cammarato et al., 2011, PLoS ONE 6(4): Table S1. Proteins & Peptides. [FBrf0214682] The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518]
Personal communication to FlyBase	Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] FlyBase Curators et al., 2004-, Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. [FBrf0174215] Ryder, 2004.4.26, Exelixis CG deletion data. Exelixis CG deletion data. [FBrf0184335]
FlyBase analysis	FlyBase Curators, 2008, Insertion identifiers and alleles based on genomic location of insertions with respect to gene annotations. Insertion identifiers and alleles based on genomic location of insertions with respect to gene annotations. [FBrf0202955] FlyBase, 1992-, FlyBase curation FlyBase curation. [FBrf0105495]
Computer file	Gene Disruption Project members and Exelixis, 2005, Genomic mapping of Exelixis insertion collection. Genomic mapping of Exelixis insertion collection. [FBrf0184340] Gene Disruption Project members, 2001-, [title not yet available] [title not yet available] [FBrf0132177] BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. Berkeley Drosophila Genome Project. [FBrf0125078]
Automatic genome annotation	FamiliarityBreedsContempt, 1999.11, [Annotations performed at the Celera Jamboreee.] [Annotations performed at the Celera Jamboreee.] [FBrf0126705]
Curated genome annotation	Lei, 1999.11, [Annotations performed at the Celera Jamboreee.] [Annotations performed at the Celera Jamboreee.] [FBrf0126680]