FB2025_01 , released February 20, 2025
Gene: Dmel\CG10163
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General Information
Symbol
Dmel\CG10163
Species
D. melanogaster
Name
Annotation Symbol
CG10163
Feature Type
protein_coding_gene
FlyBase ID
FBgn0035697
Gene Model Status
Current
Stock Availability
5 publicly available
Enzyme Name (EC)
triacylglycerol lipase (3.1.1.3)
Gene Summary
Predicted to enable triacylglycerol lipase activity. Predicted to be involved in lipid catabolic process. Predicted to be active in extracellular space. Human ortholog(s) of this gene implicated in several diseases, including cardiovascular system disease (multiple); familial hyperlipidemia (multiple); hypotrichosis 7; obesity; and type 2 diabetes mellitus. Orthologous to several human genes including LIPC (lipase C, hepatic type); LIPG (lipase G, endothelial type); and LIPH (lipase H). (Alliance, FBgn0035697 )
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Key Links
Genomic Location
Cytogenetic map
65A10-65A11
Sequence location
Recombination map
3-16
RefSeq locus
NT_037436 REGION:6257423..6258760
Sequence
Get Decorated FASTA
Genomic Maps
Other Genome Views
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UCSC
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Function

GO Summary Ribbons

enzyme
regulator
receptor
receptor binding
transporter
structural molecule
cytoskeletal binding
DNA binding
RNA binding
transcription factor
small molecule binding
metal ion binding
lipid binding
carbohydrate binding
other molecular_function
molecular function
cell cycle/proliferation
cell organization/biogenesis
transport/localization
development
reproduction
immune system
nervous system process
behavior
response to stimulus
signaling
gene expression
protein metabolism
DNA metabolism
small molecule metabolism
other biological_process
biological process
extracellular region
cytosol
cytoskeleton
mitochondrion
nucleus
chromosome
membrane
cell periphery
cell junction
cell projection
endomembrane system
synapse
macromolecular complex
other cellular_component
cellular component
Gene Ontology (GO) Annotations (4 terms)
Molecular Function (2 terms)
Biological Process (1 term)
Cellular Component (1 term)
Gene Group (FlyBase)
Protein Family (UniProt)
-
Protein Signatures (InterPro)
Catalytic Activity (EC/Rhea)
triacylglycerol lipase activity
a triacylglycerol + H2O = a diacylglycerol + a fatty acid + H(+) (3.1.1.3)
RHEA 12044:
Summaries
Gene Model and Products
Expression Data

Gene ToolKit

Alleles, Insertions, Transgenic Constructs, and Aberrations
Variants
Phenotypes
Orthologs
Paralogs
Human Disease Associations
Functional Complementation Data
Interactions
Pathways
Class of Gene
Genomic Location and Detailed Mapping Data
Stocks and Reagents
Other Comments
Relationship to Other Genes
Nomenclature History
Synonyms and Secondary IDs (1)
Datasets (0)
External Crossreferences and Linkouts ( 33 )
References (31)