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Gene Dmel\Ubc12

General Information
Symbol	Dmel\Ubc12	Species	D. melanogaster
Name	Ubiquitin conjugating enzyme 12	Annotation symbol	CG7375
Feature type	protein_coding_gene	FlyBase ID	FBgn0035853
Gene Model Status	Current	Stock availability	8 publicly available
Genomic Location
Chromosome (arm)	3L	Recombination map
Cytogenetic map	66B12-66B12	Sequence location	3L:8,188,947..8,191,087 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene Ubiquitin conjugating enzyme 12 is referred to in FlyBase by the symbol Dmel\Ubc12 (CG7375, FBgn0035853). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: NEDD8 ligase activity. There is experimental evidence that it is involved in the biological process: protein neddylation; negative regulation of smoothened signaling pathway. 8 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. Protein features are: Ubiquitin-conjugating enzyme, E2; Ubiquitin-conjugating enzyme, active site; Ubiquitin-conjugating enzyme/RWD-like. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression. Peak expression observed within 00-06 hour embryonic stages. Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: larval central nervous system, adult midgut, larval Malpighian tubules, larval fat body, larval salivary gland, larval trachea, adult ovary, adult testis. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, adult central nervous system, adult crop, larval midgut, larval/adult hindgut, adult Malpighian tubules, adult heart, adult fat body, adult salivary gland, adult spermathecae, adult male accessory gland, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1630816_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG7375. Gene sequence location is 3L:8188947..8191087.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 66B12-66B12   Limits computationally determined from genome sequence between P{lacW}Nmtj1C7 and P{lacW}l(3)L0139L0139
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\Ubc12 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.45
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) Ubc12-RA FBtr0076722  NM_139930   913   181 Ubc12-RB FBtr0332138  NM_001274638   916   181 Ubc12-RC FBtr0332139  NM_001274639   1729   181
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein Ubc12-PA   FBpp0076445   20.7   181   7.21     NP_648187   AAF50468 Ubc12-PB   FBpp0304448   20.7   181   7.21     NP_001261567   AGB94262 Ubc12-PC   FBpp0304449   20.7   181   7.21     NP_001261568   AGB94263
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Ubiquitin-conjugating enzyme, E2 (IPR000608) Ubiquitin-conjugating enzyme/RWD-like (IPR016135) Ubiquitin-conjugating enzyme, active site (IPR023313)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA951181   AA951660   AA952265   AA990765   AE014296 AAF50468   AE014296 AGB94262   AE014296 AGB94263   AI259832   AI404692   AI519570   AI946646   AW942962   AX094185   AY118545 AAM49914   AY231667   BE977908   BI170560   BI362471   BI362946   BI366843   BI373918   BI578212   BI622682   BP551910   BP557331   BP558728   BP559990   CK658672   CO177465   CO264478   CO277144   CO295286   CO301913   CO316425   CO318055   CO332319   CO336556   CZ480615   EC051769   EC052815   EC055171   EC079244   EC195700   EC201643   EC204005   EC220582   EC238767   EC244296   EC264203   GH747892   GH748690   GH754807   GH755087   GH757784   GH772411   GH776753   GH780165   GH780182   GH782305   GH782816   GH783114   GH790631   GH791437   GH792535   GH794517   GH795027   GH795373   GH804797   GH818456   GH819304   GH823141   GH823460   GH825687   GH826573   GH826735   GH827916   GH827995   GH834337   GH836989   GH837994   GH838413   GH842007   GH848057   GH850225   GH851028   GH854242   GH857173   GH861853   GH866797   GH871403   GH871940   GH875017   GH875107   GH875693   GH876522   GH883128   GH883422   GH885015   GH885264   GH886473   GH887445   GH889551   GH895298   GH897230   GH900136   GH904469   GH908291   GH908461   GH908900   GH911141   GH911838   GH913600   GH916337   GH918660   GH919038   GH919675   GH920834   GH921347   GH922052   GH923610   GH923710   GH924262   GH924977   GH926673   GH928812   GH929386   GH934775   GH935575   GH938073   GH939019   GH940699   GH942345
UniProtKB/Swiss-Prot	Q9VSF3
UniProtKB/TrEMBL
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
in situ Stage Tissue/Position (including subcellular localization) Reference embryonic stage 1 -- 3   organism   (Fisher et al., 2012) Comment:maternally deposited embryonic stage 4 -- 6   organism | ubiquitous   (Fisher et al., 2012) embryonic stage 7 -- 8   organism | ubiquitous   (Fisher et al., 2012) embryonic stage 9 -- 10   organism | ubiquitous   (Fisher et al., 2012) embryonic stage 11 -- 12   organism | ubiquitous   (Fisher et al., 2012) embryonic stage 13 -- 16   organism | ubiquitous   (Fisher et al., 2012)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: larval central nervous system, adult midgut, larval Malpighian tubules, larval fat body, larval salivary gland, larval trachea, adult ovary, adult testis. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, adult central nervous system, adult crop, larval midgut, larval/adult hindgut, adult Malpighian tubules, adult heart, adult fat body, adult salivary gland, adult spermathecae, adult male accessory gland, larval/adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    576.9 Larval Midgut    491.2 Larval Hindgut    440 Larval Malpighian Tubules    804.9 Larval Fat Body    703.8 Larval Salivary Gland    664 Larval Trachea    506.325 Larval Carcass    465.05 Adult Head    286.4 Adult Eye    329.025 Adult Brain    224.1 Adult Thoracic-Abdominal Ganglion    200.3 Adult Crop    391.1 Adult Midgut    563.4 Adult Hindgut    383 Adult Malpighian Tubules    369.4 Adult Fat Body    321.7 Adult Salivary Gland    499.2 Adult Heart    380.625 Adult VirginFemale Spermatheca    238.8 Adult InseminatedFemale Spermatheca    236.6 Adult Ovary    643.1 Adult Testis    603.9 Adult Male Accessory Gland    438.4 Adult Carcass    270.8 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System  (576.9) Larval Midgut    491.2 Larval Hindgut    440 Larval Malpighian Tubules  (804.9) Larval Fat Body  (703.8) Larval Salivary Gland  (664) Larval Trachea  506.325 Larval Carcass    465.05 Adult Head    286.4 Adult Eye    329.025 Adult Brain    224.1 Adult Thoracic-Abdominal Ganglion    200.3 Adult Crop    391.1 Adult Midgut  (563.4) Adult Hindgut    383 Adult Malpighian Tubules    369.4 Adult Fat Body    321.7 Adult Salivary Gland    499.2 Adult Heart    380.625 Adult VirginFemale Spermatheca    238.8 Adult InseminatedFemale Spermatheca    236.6 Adult Ovary  (643.1) Adult Testis  (603.9) Adult Male Accessory Gland    438.4 Adult Carcass    270.8 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    576.9 Larval Midgut    491.2 Larval Hindgut    440 Larval Malpighian Tubules    804.9 Larval Fat Body    703.8 Larval Salivary Gland    664 Larval Trachea    506.325 Larval Carcass    465.05 Adult Head    286.4 Adult Eye    329.025 Adult Brain    224.1 Adult Thoracic-Abdominal Ganglion    200.3 Adult Crop    391.1 Adult Midgut    563.4 Adult Hindgut    383 Adult Malpighian Tubules    369.4 Adult Fat Body    321.7 Adult Salivary Gland    499.2 Adult Heart    380.625 Adult VirginFemale Spermatheca    238.8 Adult InseminatedFemale Spermatheca    236.6 Adult Ovary    643.1 Adult Testis    603.9 Adult Male Accessory Gland    438.4 Adult Carcass    270.8 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    576.9 Larval Midgut    491.2 Larval Hindgut    440 Larval Malpighian Tubules    804.9 Larval Fat Body    703.8 Larval Salivary Gland    664 Larval Trachea    506.325 Larval Carcass    465.05 Adult Head    286.4 Adult Eye    329.025 Adult Brain    224.1 Adult Thoracic-Abdominal Ganglion    200.3 Adult Crop    391.1 Adult Midgut    563.4 Adult Hindgut    383 Adult Malpighian Tubules    369.4 Adult Fat Body    321.7 Adult Salivary Gland    499.2 Adult Heart    380.625 Adult VirginFemale Spermatheca    238.8 Adult InseminatedFemale Spermatheca    236.6 Adult Ovary    643.1 Adult Testis    603.9 Adult Male Accessory Gland    438.4 Adult Carcass    270.8 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    576.9 Larval Midgut    491.2 Larval Hindgut    440 Larval Malpighian Tubules    804.9 Larval Fat Body    703.8 Larval Salivary Gland    664 Larval Trachea    506.325 Larval Carcass    465.05 Adult Head    286.4 Adult Eye    329.025 Adult Brain    224.1 Adult Thoracic-Abdominal Ganglion    200.3 Adult Crop    391.1 Adult Midgut    563.4 Adult Hindgut    383 Adult Malpighian Tubules    369.4 Adult Fat Body    321.7 Adult Salivary Gland    499.2 Adult Heart    380.625 Adult VirginFemale Spermatheca    238.8 Adult InseminatedFemale Spermatheca    236.6 Adult Ovary    643.1 Adult Testis    603.9 Adult Male Accessory Gland    438.4 Adult Carcass    270.8 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System  576.9 Larval Midgut    491.2 Larval Hindgut    440 Larval Malpighian Tubules  804.9 Larval Fat Body  703.8 Larval Salivary Gland  664 Larval Trachea  506.325 Larval Carcass    465.05 Adult Head    286.4 Adult Eye    329.025 Adult Brain    224.1 Adult Thoracic-Abdominal Ganglion    200.3 Adult Crop    391.1 Adult Midgut  563.4 Adult Hindgut    383 Adult Malpighian Tubules    369.4 Adult Fat Body    321.7 Adult Salivary Gland    499.2 Adult Heart    380.625 Adult VirginFemale Spermatheca    238.8 Adult InseminatedFemale Spermatheca    236.6 Adult Ovary  643.1 Adult Testis  603.9 Adult Male Accessory Gland    438.4 Adult Carcass    270.8 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    576.9 Larval Midgut    491.2 Larval Hindgut    440 Larval Malpighian Tubules    804.9 Larval Fat Body    703.8 Larval Salivary Gland    664 Larval Trachea    506.325 Larval Carcass    465.05 Adult Head    286.4 Adult Eye    329.025 Adult Brain    224.1 Adult Thoracic-Abdominal Ganglion    200.3 Adult Crop    391.1 Adult Midgut    563.4 Adult Hindgut    383 Adult Malpighian Tubules    369.4 Adult Fat Body    321.7 Adult Salivary Gland    499.2 Adult Heart    380.625 Adult VirginFemale Spermatheca    238.8 Adult InseminatedFemale Spermatheca    236.6 Adult Ovary    643.1 Adult Testis    603.9 Adult Male Accessory Gland    438.4 Adult Carcass    270.8 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    576.9 Larval Midgut    491.2 Larval Hindgut    440 Larval Malpighian Tubules    804.9 Larval Fat Body    703.8 Larval Salivary Gland    664 Larval Trachea    506.325 Larval Carcass    465.05 Adult Head    286.4 Adult Eye    329.025 Adult Brain    224.1 Adult Thoracic-Abdominal Ganglion    200.3 Adult Crop    391.1 Adult Midgut    563.4 Adult Hindgut    383 Adult Malpighian Tubules    369.4 Adult Fat Body    321.7 Adult Salivary Gland    499.2 Adult Heart    380.625 Adult VirginFemale Spermatheca    238.8 Adult InseminatedFemale Spermatheca    236.6 Adult Ovary    643.1 Adult Testis    603.9 Adult Male Accessory Gland    438.4 Adult Carcass    270.8 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    286.4   NA  Eye    329.025   NA  Brain    224.1   576.9  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    200.3   NA  Crop    391.1   491.2  Midgut    563.4   440  Hindgut    383   804.9  Malpighian Tubules    369.4   703.8  Fat Body    321.7   664  Salivary Gland    499.2   NA  Heart    380.625   506.325  Trachea    NA   NA  VirginFemale Spermatheca    238.8   NA  InseminatedFemale Spermatheca    236.6   NA  Ovary    643.1   NA  Testis    603.9   NA  Male Accessory Gland    438.4   465.05  Carcass    270.8 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    73 central nervous system, larvae L3    64 central nervous system, pupae P8    34 head, virgin 1-day female    22 head, virgin 4-day female    19 head, virgin 20-day female    17 head, mated 1-day female    20 head, mated 4-day female    16 head, mated 20-day female    18 head, mated 1-day male    25 head, mated 4-day male    25 head, mated 20-day male    26 salivary gland, larvae L3 wandering    72 salivary gland, white prepupae    450 digestive system, larvae L3 wandering    63 digestive system, 1-day adult    32 digestive system, 4-day adult    26 digestive system, 20-day adult    24 fat body, larvae L3 wandering    16 fat body, white prepupae    49 fat body, pupae P8    44 carcass, larvae L3 wandering    45 carcass, 1-day adult    18 carcass, 4-day adult    18 carcass, 20-day adult    19 ovary, virgin 4-day female    59 ovary, mated 4-day female    51 testis, mated 4-day male    75 accessory gland, mated 4-day male    25 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (73) central nervous system, larvae L3  (64) central nervous system, pupae P8  (34) head, virgin 1-day female    22 head, virgin 4-day female    19 head, virgin 20-day female    17 head, mated 1-day female    20 head, mated 4-day female    16 head, mated 20-day female    18 head, mated 1-day male    25 head, mated 4-day male    25 head, mated 20-day male  26 salivary gland, larvae L3 wandering  (72) salivary gland, white prepupae  (450) digestive system, larvae L3 wandering  (63) digestive system, 1-day adult  (32) digestive system, 4-day adult  26 digestive system, 20-day adult    24 fat body, larvae L3 wandering    16 fat body, white prepupae  (49) fat body, pupae P8  (44) carcass, larvae L3 wandering  (45) carcass, 1-day adult    18 carcass, 4-day adult    18 carcass, 20-day adult    19 ovary, virgin 4-day female  (59) ovary, mated 4-day female  (51) testis, mated 4-day male  (75) accessory gland, mated 4-day male    25 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    73 central nervous system, larvae L3    64 central nervous system, pupae P8    34 head, virgin 1-day female    22 head, virgin 4-day female    19 head, virgin 20-day female    17 head, mated 1-day female    20 head, mated 4-day female    16 head, mated 20-day female    18 head, mated 1-day male    25 head, mated 4-day male    25 head, mated 20-day male    26 salivary gland, larvae L3 wandering    72 salivary gland, white prepupae  (450) digestive system, larvae L3 wandering    63 digestive system, 1-day adult    32 digestive system, 4-day adult    26 digestive system, 20-day adult    24 fat body, larvae L3 wandering    16 fat body, white prepupae    49 fat body, pupae P8    44 carcass, larvae L3 wandering    45 carcass, 1-day adult    18 carcass, 4-day adult    18 carcass, 20-day adult    19 ovary, virgin 4-day female    59 ovary, mated 4-day female    51 testis, mated 4-day male    75 accessory gland, mated 4-day male    25 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    73 central nervous system, larvae L3    64 central nervous system, pupae P8    34 head, virgin 1-day female    22 head, virgin 4-day female    19 head, virgin 20-day female    17 head, mated 1-day female    20 head, mated 4-day female    16 head, mated 20-day female    18 head, mated 1-day male    25 head, mated 4-day male    25 head, mated 20-day male    26 salivary gland, larvae L3 wandering    72 salivary gland, white prepupae    450 digestive system, larvae L3 wandering    63 digestive system, 1-day adult    32 digestive system, 4-day adult    26 digestive system, 20-day adult    24 fat body, larvae L3 wandering    16 fat body, white prepupae    49 fat body, pupae P8    44 carcass, larvae L3 wandering    45 carcass, 1-day adult    18 carcass, 4-day adult    18 carcass, 20-day adult    19 ovary, virgin 4-day female    59 ovary, mated 4-day female    51 testis, mated 4-day male    75 accessory gland, mated 4-day male    25 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    73 central nervous system, larvae L3    64 central nervous system, pupae P8    34 head, virgin 1-day female    22 head, virgin 4-day female    19 head, virgin 20-day female    17 head, mated 1-day female    20 head, mated 4-day female    16 head, mated 20-day female    18 head, mated 1-day male    25 head, mated 4-day male    25 head, mated 20-day male    26 salivary gland, larvae L3 wandering    72 salivary gland, white prepupae    450 digestive system, larvae L3 wandering    63 digestive system, 1-day adult    32 digestive system, 4-day adult    26 digestive system, 20-day adult    24 fat body, larvae L3 wandering    16 fat body, white prepupae    49 fat body, pupae P8    44 carcass, larvae L3 wandering    45 carcass, 1-day adult    18 carcass, 4-day adult    18 carcass, 20-day adult    19 ovary, virgin 4-day female    59 ovary, mated 4-day female    51 testis, mated 4-day male    75 accessory gland, mated 4-day male    25 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (73) central nervous system, larvae L3  (64) central nervous system, pupae P8  (34) head, virgin 1-day female    22 head, virgin 4-day female    19 head, virgin 20-day female    17 head, mated 1-day female    20 head, mated 4-day female    16 head, mated 20-day female    18 head, mated 1-day male    25 head, mated 4-day male    25 head, mated 20-day male  26 salivary gland, larvae L3 wandering  (72) salivary gland, white prepupae  (450) digestive system, larvae L3 wandering  (63) digestive system, 1-day adult  32 digestive system, 4-day adult  26 digestive system, 20-day adult    24 fat body, larvae L3 wandering    16 fat body, white prepupae  (49) fat body, pupae P8  (44) carcass, larvae L3 wandering  (45) carcass, 1-day adult    18 carcass, 4-day adult    18 carcass, 20-day adult    19 ovary, virgin 4-day female  (59) ovary, mated 4-day female  (51) testis, mated 4-day male  (75) accessory gland, mated 4-day male    25 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    73 central nervous system, larvae L3    64 central nervous system, pupae P8    34 head, virgin 1-day female    22 head, virgin 4-day female    19 head, virgin 20-day female    17 head, mated 1-day female    20 head, mated 4-day female    16 head, mated 20-day female    18 head, mated 1-day male    25 head, mated 4-day male    25 head, mated 20-day male    26 salivary gland, larvae L3 wandering    72 salivary gland, white prepupae  (450) digestive system, larvae L3 wandering    63 digestive system, 1-day adult    32 digestive system, 4-day adult    26 digestive system, 20-day adult    24 fat body, larvae L3 wandering    16 fat body, white prepupae    49 fat body, pupae P8    44 carcass, larvae L3 wandering    45 carcass, 1-day adult    18 carcass, 4-day adult    18 carcass, 20-day adult    19 ovary, virgin 4-day female    59 ovary, mated 4-day female    51 testis, mated 4-day male    75 accessory gland, mated 4-day male    25 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    73 central nervous system, larvae L3    64 central nervous system, pupae P8    34 head, virgin 1-day female    22 head, virgin 4-day female    19 head, virgin 20-day female    17 head, mated 1-day female    20 head, mated 4-day female    16 head, mated 20-day female    18 head, mated 1-day male    25 head, mated 4-day male    25 head, mated 20-day male    26 salivary gland, larvae L3 wandering    72 salivary gland, white prepupae    450 digestive system, larvae L3 wandering    63 digestive system, 1-day adult    32 digestive system, 4-day adult    26 digestive system, 20-day adult    24 fat body, larvae L3 wandering    16 fat body, white prepupae    49 fat body, pupae P8    44 carcass, larvae L3 wandering    45 carcass, 1-day adult    18 carcass, 4-day adult    18 carcass, 20-day adult    19 ovary, virgin 4-day female    59 ovary, mated 4-day female    51 testis, mated 4-day male    75 accessory gland, mated 4-day male    25 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression. Peak expression observed within 00-06 hour embryonic stages. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    86 embryo 02-04hr    140 embryo 04-06hr    139 embryo 06-08hr    98 embryo 08-10hr    83 embryo 10-12hr    71 embryo 12-14hr    55 embryo 14-16hr    38 embryo 16-18hr    40 embryo 18-20hr    34 embryo 20-22hr    31 embryo 22-24hr    34 larva L1    30 larva L2    37 larva L3 12hr old    33 larva L3 puffstage 1-2    43 larva L3 puffstage 3-6    53 larva L3 puffstage 7-9    85 white prepupae new    104 white prepupae 12hr    88 white prepupae 24hr    75 pupae 2d postWPP    68 pupae 3d postWPP    42 pupae 4d postWPP    42 adult male 01day    40 adult male 05day    46 adult male 30day    36 adult female 01day    36 adult female 05day    59 adult female 30day    60 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (86) embryo 02-04hr  (140) embryo 04-06hr  (139) embryo 06-08hr  (98) embryo 08-10hr  (83) embryo 10-12hr  (71) embryo 12-14hr  (55) embryo 14-16hr  (38) embryo 16-18hr  (40) embryo 18-20hr  (34) embryo 20-22hr  (31) embryo 22-24hr  (34) larva L1  (30) larva L2  (37) larva L3 12hr old  (33) larva L3 puffstage 1-2  (43) larva L3 puffstage 3-6  (53) larva L3 puffstage 7-9  (85) white prepupae new  (104) white prepupae 12hr  (88) white prepupae 24hr  (75) pupae 2d postWPP  (68) pupae 3d postWPP  (42) pupae 4d postWPP  (42) adult male 01day  (40) adult male 05day  (46) adult male 30day  (36) adult female 01day  (36) adult female 05day  (59) adult female 30day  (60) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    86 embryo 02-04hr  (140) embryo 04-06hr  (139) embryo 06-08hr    98 embryo 08-10hr    83 embryo 10-12hr    71 embryo 12-14hr    55 embryo 14-16hr    38 embryo 16-18hr    40 embryo 18-20hr    34 embryo 20-22hr    31 embryo 22-24hr    34 larva L1    30 larva L2    37 larva L3 12hr old    33 larva L3 puffstage 1-2    43 larva L3 puffstage 3-6    53 larva L3 puffstage 7-9    85 white prepupae new  104 white prepupae 12hr    88 white prepupae 24hr    75 pupae 2d postWPP    68 pupae 3d postWPP    42 pupae 4d postWPP    42 adult male 01day    40 adult male 05day    46 adult male 30day    36 adult female 01day    36 adult female 05day    59 adult female 30day    60 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    86 embryo 02-04hr    140 embryo 04-06hr    139 embryo 06-08hr    98 embryo 08-10hr    83 embryo 10-12hr    71 embryo 12-14hr    55 embryo 14-16hr    38 embryo 16-18hr    40 embryo 18-20hr    34 embryo 20-22hr    31 embryo 22-24hr    34 larva L1    30 larva L2    37 larva L3 12hr old    33 larva L3 puffstage 1-2    43 larva L3 puffstage 3-6    53 larva L3 puffstage 7-9    85 white prepupae new    104 white prepupae 12hr    88 white prepupae 24hr    75 pupae 2d postWPP    68 pupae 3d postWPP    42 pupae 4d postWPP    42 adult male 01day    40 adult male 05day    46 adult male 30day    36 adult female 01day    36 adult female 05day    59 adult female 30day    60 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    86 embryo 02-04hr    140 embryo 04-06hr    139 embryo 06-08hr    98 embryo 08-10hr    83 embryo 10-12hr    71 embryo 12-14hr    55 embryo 14-16hr    38 embryo 16-18hr    40 embryo 18-20hr    34 embryo 20-22hr    31 embryo 22-24hr    34 larva L1    30 larva L2    37 larva L3 12hr old    33 larva L3 puffstage 1-2    43 larva L3 puffstage 3-6    53 larva L3 puffstage 7-9    85 white prepupae new    104 white prepupae 12hr    88 white prepupae 24hr    75 pupae 2d postWPP    68 pupae 3d postWPP    42 pupae 4d postWPP    42 adult male 01day    40 adult male 05day    46 adult male 30day    36 adult female 01day    36 adult female 05day    59 adult female 30day    60 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (86) embryo 02-04hr  (140) embryo 04-06hr  (139) embryo 06-08hr  (98) embryo 08-10hr  (83) embryo 10-12hr  (71) embryo 12-14hr  (55) embryo 14-16hr  (38) embryo 16-18hr  (40) embryo 18-20hr  (34) embryo 20-22hr  31 embryo 22-24hr  (34) larva L1  30 larva L2  (37) larva L3 12hr old  (33) larva L3 puffstage 1-2  (43) larva L3 puffstage 3-6  (53) larva L3 puffstage 7-9  (85) white prepupae new  (104) white prepupae 12hr  (88) white prepupae 24hr  (75) pupae 2d postWPP  (68) pupae 3d postWPP  (42) pupae 4d postWPP  (42) adult male 01day  (40) adult male 05day  (46) adult male 30day  (36) adult female 01day  (36) adult female 05day  (59) adult female 30day  (60) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    86 embryo 02-04hr  140 embryo 04-06hr  139 embryo 06-08hr    98 embryo 08-10hr    83 embryo 10-12hr    71 embryo 12-14hr    55 embryo 14-16hr    38 embryo 16-18hr    40 embryo 18-20hr    34 embryo 20-22hr    31 embryo 22-24hr    34 larva L1    30 larva L2    37 larva L3 12hr old    33 larva L3 puffstage 1-2    43 larva L3 puffstage 3-6    53 larva L3 puffstage 7-9    85 white prepupae new  104 white prepupae 12hr    88 white prepupae 24hr    75 pupae 2d postWPP    68 pupae 3d postWPP    42 pupae 4d postWPP    42 adult male 01day    40 adult male 05day    46 adult male 30day    36 adult female 01day    36 adult female 05day    59 adult female 30day    60 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    86 embryo 02-04hr    140 embryo 04-06hr    139 embryo 06-08hr    98 embryo 08-10hr    83 embryo 10-12hr    71 embryo 12-14hr    55 embryo 14-16hr    38 embryo 16-18hr    40 embryo 18-20hr    34 embryo 20-22hr    31 embryo 22-24hr    34 larva L1    30 larva L2    37 larva L3 12hr old    33 larva L3 puffstage 1-2    43 larva L3 puffstage 3-6    53 larva L3 puffstage 7-9    85 white prepupae new    104 white prepupae 12hr    88 white prepupae 24hr    75 pupae 2d postWPP    68 pupae 3d postWPP    42 pupae 4d postWPP    42 adult male 01day    40 adult male 05day    46 adult male 30day    36 adult female 01day    36 adult female 05day    59 adult female 30day    60 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    62 Schneider line 2 Sg4    48 embryonic 1182-4H    55 embryonic GM2    47 embryonic Kc167    46 embryonic S1    109 embryonic S3    50 leg disc CME L1    63 wing disc CME-W2    83 wing disc ML-DmD8    52 wing disc ML-DmD9    102 wing disc ML-DmD16-c3    57 wing disc ML-DmD21    73 wing disc ML-DmD32    57 haltere disc ML-DmD17-c3    63 eye-antennal disc ML-DmD11    75 antennal disc ML-DmD20-c5    77 mixed discs ML-DmD4-c1    64 CNS ML-DmBG1-c1    66 CNS ML-DmBG2-c2    57 tumorous blood cells mbn2    48 ovary fGS/OSS    62 ovary OSC    73 ovary OSS    32 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (62) Schneider line 2 Sg4  (48) embryonic 1182-4H  (55) embryonic GM2  (47) embryonic Kc167  (46) embryonic S1  (109) embryonic S3  (50) leg disc CME L1  (63) wing disc CME-W2  (83) wing disc ML-DmD8  (52) wing disc ML-DmD9  (102) wing disc ML-DmD16-c3  (57) wing disc ML-DmD21  (73) wing disc ML-DmD32  (57) haltere disc ML-DmD17-c3  (63) eye-antennal disc ML-DmD11  (75) antennal disc ML-DmD20-c5  (77) mixed discs ML-DmD4-c1  (64) CNS ML-DmBG1-c1  (66) CNS ML-DmBG2-c2  (57) tumorous blood cells mbn2  (48) ovary fGS/OSS  (62) ovary OSC  (73) ovary OSS  (32) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    62 Schneider line 2 Sg4    48 embryonic 1182-4H    55 embryonic GM2    47 embryonic Kc167    46 embryonic S1  (109) embryonic S3    50 leg disc CME L1    63 wing disc CME-W2    83 wing disc ML-DmD8    52 wing disc ML-DmD9  102 wing disc ML-DmD16-c3    57 wing disc ML-DmD21    73 wing disc ML-DmD32    57 haltere disc ML-DmD17-c3    63 eye-antennal disc ML-DmD11    75 antennal disc ML-DmD20-c5    77 mixed discs ML-DmD4-c1    64 CNS ML-DmBG1-c1    66 CNS ML-DmBG2-c2    57 tumorous blood cells mbn2    48 ovary fGS/OSS    62 ovary OSC    73 ovary OSS    32 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    62 Schneider line 2 Sg4    48 embryonic 1182-4H    55 embryonic GM2    47 embryonic Kc167    46 embryonic S1    109 embryonic S3    50 leg disc CME L1    63 wing disc CME-W2    83 wing disc ML-DmD8    52 wing disc ML-DmD9    102 wing disc ML-DmD16-c3    57 wing disc ML-DmD21    73 wing disc ML-DmD32    57 haltere disc ML-DmD17-c3    63 eye-antennal disc ML-DmD11    75 antennal disc ML-DmD20-c5    77 mixed discs ML-DmD4-c1    64 CNS ML-DmBG1-c1    66 CNS ML-DmBG2-c2    57 tumorous blood cells mbn2    48 ovary fGS/OSS    62 ovary OSC    73 ovary OSS    32 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    62 Schneider line 2 Sg4    48 embryonic 1182-4H    55 embryonic GM2    47 embryonic Kc167    46 embryonic S1    109 embryonic S3    50 leg disc CME L1    63 wing disc CME-W2    83 wing disc ML-DmD8    52 wing disc ML-DmD9    102 wing disc ML-DmD16-c3    57 wing disc ML-DmD21    73 wing disc ML-DmD32    57 haltere disc ML-DmD17-c3    63 eye-antennal disc ML-DmD11    75 antennal disc ML-DmD20-c5    77 mixed discs ML-DmD4-c1    64 CNS ML-DmBG1-c1    66 CNS ML-DmBG2-c2    57 tumorous blood cells mbn2    48 ovary fGS/OSS    62 ovary OSC    73 ovary OSS    32 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (62) Schneider line 2 Sg4  (48) embryonic 1182-4H  (55) embryonic GM2  (47) embryonic Kc167  (46) embryonic S1  (109) embryonic S3  (50) leg disc CME L1  (63) wing disc CME-W2  (83) wing disc ML-DmD8  (52) wing disc ML-DmD9  (102) wing disc ML-DmD16-c3  (57) wing disc ML-DmD21  (73) wing disc ML-DmD32  (57) haltere disc ML-DmD17-c3  (63) eye-antennal disc ML-DmD11  (75) antennal disc ML-DmD20-c5  (77) mixed discs ML-DmD4-c1  (64) CNS ML-DmBG1-c1  (66) CNS ML-DmBG2-c2  (57) tumorous blood cells mbn2  (48) ovary fGS/OSS  (62) ovary OSC  (73) ovary OSS  32 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    62 Schneider line 2 Sg4    48 embryonic 1182-4H    55 embryonic GM2    47 embryonic Kc167    46 embryonic S1  109 embryonic S3    50 leg disc CME L1    63 wing disc CME-W2    83 wing disc ML-DmD8    52 wing disc ML-DmD9  102 wing disc ML-DmD16-c3    57 wing disc ML-DmD21    73 wing disc ML-DmD32    57 haltere disc ML-DmD17-c3    63 eye-antennal disc ML-DmD11    75 antennal disc ML-DmD20-c5    77 mixed discs ML-DmD4-c1    64 CNS ML-DmBG1-c1    66 CNS ML-DmBG2-c2    57 tumorous blood cells mbn2    48 ovary fGS/OSS    62 ovary OSC    73 ovary OSS    32 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    62 Schneider line 2 Sg4    48 embryonic 1182-4H    55 embryonic GM2    47 embryonic Kc167    46 embryonic S1    109 embryonic S3    50 leg disc CME L1    63 wing disc CME-W2    83 wing disc ML-DmD8    52 wing disc ML-DmD9    102 wing disc ML-DmD16-c3    57 wing disc ML-DmD21    73 wing disc ML-DmD32    57 haltere disc ML-DmD17-c3    63 eye-antennal disc ML-DmD11    75 antennal disc ML-DmD20-c5    77 mixed discs ML-DmD4-c1    64 CNS ML-DmBG1-c1    66 CNS ML-DmBG2-c2    57 tumorous blood cells mbn2    48 ovary fGS/OSS    62 ovary OSC    73 ovary OSS    32 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    35 cold shock, 4-day adult    29 heat shock, 4-day adult    32 Cadmium 50 mM 6 hrs, larvae L3    29 Cadmium 50 mM 12 hrs, larvae L3    50 Cadmium 50 mM 48 hrs, 4-day adult    33 Cadmium 100 mM 48 hrs, 4-day adult    48 Copper 0.5 mM 12 hrs, larvae L3    21 Copper 15 mM 48 hrs, 4-day adult    32 Zinc 5 mM 12 hrs, larvae L3    18 Zinc 4.5 mM 48 hrs, 4-day adult    30 Ethanol 2.5% 3 hrs, larvae L3    40 Ethanol 5% 3 hrs, larvae L3    32 Ethanol 10% 3 hrs, larvae L3    27 Caffeine 1.5 mg/ml 4 hrs, larvae L3    27 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    47 Caffeine 25 mg/ml 48 hrs, 4-day adult    24 Paraquat 5 mM 48 hrs, 4-day adult    36 Paraquat 10 mM 48 hrs, 4-day adult    36 Rotenone 2 μg 12 hrs, larvae L3    37 Rotenone 8 μg 12 hrs, larvae L3    32 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult  (35) cold shock, 4-day adult  (29) heat shock, 4-day adult  (32) Cadmium 50 mM 6 hrs, larvae L3  (29) Cadmium 50 mM 12 hrs, larvae L3  (50) Cadmium 50 mM 48 hrs, 4-day adult  (33) Cadmium 100 mM 48 hrs, 4-day adult  (48) Copper 0.5 mM 12 hrs, larvae L3    21 Copper 15 mM 48 hrs, 4-day adult  (32) Zinc 5 mM 12 hrs, larvae L3    18 Zinc 4.5 mM 48 hrs, 4-day adult  (30) Ethanol 2.5% 3 hrs, larvae L3  (40) Ethanol 5% 3 hrs, larvae L3  (32) Ethanol 10% 3 hrs, larvae L3  (27) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (27) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (47) Caffeine 25 mg/ml 48 hrs, 4-day adult    24 Paraquat 5 mM 48 hrs, 4-day adult  (36) Paraquat 10 mM 48 hrs, 4-day adult  (36) Rotenone 2 μg 12 hrs, larvae L3  (37) Rotenone 8 μg 12 hrs, larvae L3  (32) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    35 cold shock, 4-day adult    29 heat shock, 4-day adult    32 Cadmium 50 mM 6 hrs, larvae L3    29 Cadmium 50 mM 12 hrs, larvae L3    50 Cadmium 50 mM 48 hrs, 4-day adult    33 Cadmium 100 mM 48 hrs, 4-day adult    48 Copper 0.5 mM 12 hrs, larvae L3    21 Copper 15 mM 48 hrs, 4-day adult    32 Zinc 5 mM 12 hrs, larvae L3    18 Zinc 4.5 mM 48 hrs, 4-day adult    30 Ethanol 2.5% 3 hrs, larvae L3    40 Ethanol 5% 3 hrs, larvae L3    32 Ethanol 10% 3 hrs, larvae L3    27 Caffeine 1.5 mg/ml 4 hrs, larvae L3    27 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    47 Caffeine 25 mg/ml 48 hrs, 4-day adult    24 Paraquat 5 mM 48 hrs, 4-day adult    36 Paraquat 10 mM 48 hrs, 4-day adult    36 Rotenone 2 μg 12 hrs, larvae L3    37 Rotenone 8 μg 12 hrs, larvae L3    32 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    35 cold shock, 4-day adult    29 heat shock, 4-day adult    32 Cadmium 50 mM 6 hrs, larvae L3    29 Cadmium 50 mM 12 hrs, larvae L3    50 Cadmium 50 mM 48 hrs, 4-day adult    33 Cadmium 100 mM 48 hrs, 4-day adult    48 Copper 0.5 mM 12 hrs, larvae L3    21 Copper 15 mM 48 hrs, 4-day adult    32 Zinc 5 mM 12 hrs, larvae L3    18 Zinc 4.5 mM 48 hrs, 4-day adult    30 Ethanol 2.5% 3 hrs, larvae L3    40 Ethanol 5% 3 hrs, larvae L3    32 Ethanol 10% 3 hrs, larvae L3    27 Caffeine 1.5 mg/ml 4 hrs, larvae L3    27 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    47 Caffeine 25 mg/ml 48 hrs, 4-day adult    24 Paraquat 5 mM 48 hrs, 4-day adult    36 Paraquat 10 mM 48 hrs, 4-day adult    36 Rotenone 2 μg 12 hrs, larvae L3    37 Rotenone 8 μg 12 hrs, larvae L3    32 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    35 cold shock, 4-day adult    29 heat shock, 4-day adult    32 Cadmium 50 mM 6 hrs, larvae L3    29 Cadmium 50 mM 12 hrs, larvae L3    50 Cadmium 50 mM 48 hrs, 4-day adult    33 Cadmium 100 mM 48 hrs, 4-day adult    48 Copper 0.5 mM 12 hrs, larvae L3    21 Copper 15 mM 48 hrs, 4-day adult    32 Zinc 5 mM 12 hrs, larvae L3    18 Zinc 4.5 mM 48 hrs, 4-day adult    30 Ethanol 2.5% 3 hrs, larvae L3    40 Ethanol 5% 3 hrs, larvae L3    32 Ethanol 10% 3 hrs, larvae L3    27 Caffeine 1.5 mg/ml 4 hrs, larvae L3    27 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    47 Caffeine 25 mg/ml 48 hrs, 4-day adult    24 Paraquat 5 mM 48 hrs, 4-day adult    36 Paraquat 10 mM 48 hrs, 4-day adult    36 Rotenone 2 μg 12 hrs, larvae L3    37 Rotenone 8 μg 12 hrs, larvae L3    32 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult  (35) cold shock, 4-day adult  29 heat shock, 4-day adult  32 Cadmium 50 mM 6 hrs, larvae L3  29 Cadmium 50 mM 12 hrs, larvae L3  (50) Cadmium 50 mM 48 hrs, 4-day adult  (33) Cadmium 100 mM 48 hrs, 4-day adult  (48) Copper 0.5 mM 12 hrs, larvae L3    21 Copper 15 mM 48 hrs, 4-day adult  32 Zinc 5 mM 12 hrs, larvae L3    18 Zinc 4.5 mM 48 hrs, 4-day adult  30 Ethanol 2.5% 3 hrs, larvae L3  (40) Ethanol 5% 3 hrs, larvae L3  32 Ethanol 10% 3 hrs, larvae L3  27 Caffeine 1.5 mg/ml 4 hrs, larvae L3  27 Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (47) Caffeine 25 mg/ml 48 hrs, 4-day adult    24 Paraquat 5 mM 48 hrs, 4-day adult  (36) Paraquat 10 mM 48 hrs, 4-day adult  (36) Rotenone 2 μg 12 hrs, larvae L3  (37) Rotenone 8 μg 12 hrs, larvae L3  32 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    35 cold shock, 4-day adult    29 heat shock, 4-day adult    32 Cadmium 50 mM 6 hrs, larvae L3    29 Cadmium 50 mM 12 hrs, larvae L3    50 Cadmium 50 mM 48 hrs, 4-day adult    33 Cadmium 100 mM 48 hrs, 4-day adult    48 Copper 0.5 mM 12 hrs, larvae L3    21 Copper 15 mM 48 hrs, 4-day adult    32 Zinc 5 mM 12 hrs, larvae L3    18 Zinc 4.5 mM 48 hrs, 4-day adult    30 Ethanol 2.5% 3 hrs, larvae L3    40 Ethanol 5% 3 hrs, larvae L3    32 Ethanol 10% 3 hrs, larvae L3    27 Caffeine 1.5 mg/ml 4 hrs, larvae L3    27 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    47 Caffeine 25 mg/ml 48 hrs, 4-day adult    24 Paraquat 5 mM 48 hrs, 4-day adult    36 Paraquat 10 mM 48 hrs, 4-day adult    36 Rotenone 2 μg 12 hrs, larvae L3    37 Rotenone 8 μg 12 hrs, larvae L3    32 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    35 cold shock, 4-day adult    29 heat shock, 4-day adult    32 Cadmium 50 mM 6 hrs, larvae L3    29 Cadmium 50 mM 12 hrs, larvae L3    50 Cadmium 50 mM 48 hrs, 4-day adult    33 Cadmium 100 mM 48 hrs, 4-day adult    48 Copper 0.5 mM 12 hrs, larvae L3    21 Copper 15 mM 48 hrs, 4-day adult    32 Zinc 5 mM 12 hrs, larvae L3    18 Zinc 4.5 mM 48 hrs, 4-day adult    30 Ethanol 2.5% 3 hrs, larvae L3    40 Ethanol 5% 3 hrs, larvae L3    32 Ethanol 10% 3 hrs, larvae L3    27 Caffeine 1.5 mg/ml 4 hrs, larvae L3    27 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    47 Caffeine 25 mg/ml 48 hrs, 4-day adult    24 Paraquat 5 mM 48 hrs, 4-day adult    36 Paraquat 10 mM 48 hrs, 4-day adult    36 Rotenone 2 μg 12 hrs, larvae L3    37 Rotenone 8 μg 12 hrs, larvae L3    32 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_23 mE1_20_mRNA_expression_cluster_02
External Data & Images
Linkouts	BDGP expression data • LD29377 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0035853 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG7375-RA FlyExpress - Embryonic expression images (BDGP data) • Show all FlyExpress processed images for Ubc12 Stages(s) 1-3 Stages(s) 4-6 Stages(s) 7-8 Stages(s) 9-10 Stages(s) 11-12 Stages(s) 13-16
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal | pupal stage, with Scer\GAL4pnr-MD237 Ubc12GD12219 Phenotype manifest in Allele
Classical Alleles ( 5 )
For All Classical Alleles Show
Allele of Ubc12 Class Mutagen Stocks Known lesion Ubc12LL04684 amorphic allele - molecular evidence 1 Yes Ubc12B238 1 -- Ubc12e02842 piggyBac transposase 1 -- Ubc12EY22840 P-element activity 1 -- Ubc12MI00049 1 --
Alleles Carried on Transgenic Constructs ( 3 )
For All Alleles Carried on Transgenic Constructs Show
Allele of Ubc12 Class Mutagen Stocks Known lesion Ubc12GD12219 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes Ubc12KK108493 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes Ubc12NIG.7375R in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(3L)Exel6112 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{NIG.7375R} NA
Insertions
	Type of insertions Name Expression data miscellaneous insertions Mi{MIC}Ubc12MI00049 NA PBac{5HPw+}Ubc12B238 NA PBac{RB}Ubc12e02842 NA PBac{SAstopDsRed}Ubc12LL04684 NA insertion of mobile activating element P{EPgy2}Ubc12EY22840 NA
Gene Ontology: Function, Process & Cellular Component ( 4 unique terms )
	There is no information supporting a cellular component term for this gene. (Based on a review of available data on: 2006-10-26)
Terms Based on Experimental Evidence ( 3 terms )
Molecular Function
CV term Evidence References
NEDD8 ligase activity inferred from direct assay (Du et al., 2011)
Biological Process
CV term Evidence References
negative regulation of smoothened signaling pathway inferred from mutant phenotype (Du et al., 2011) protein neddylation inferred from direct assay (Du et al., 2011)
Cellular Component ( 0 terms)
Terms Based on Predictions or Assertions ( 1 term )
Molecular Function
CV term Evidence References
ubiquitin-protein ligase activity inferred from sequence or structural similarity with Saccharomyces UBC12 (FlyBase, 1992-)
Biological Process ( 0 terms)
Cellular Component ( 0 terms)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
protein-protein
Interacting group Assay References
Ubc12 - AnxB10 anti tag coimmunoprecipitation, peptide massfingerprinting, experimental knowledge based (Mintseris et al., 2009.11.23, Guruharsha et al., 2011) Ubc12 - Aos1 experimental knowledge based, anti tag coimmunoprecipitation, peptide massfingerprinting (Guruharsha et al., 2011, Mintseris et al., 2009.11.23) Ubc12 - Arf79F anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Ubc12 - CG15717 experimental knowledge based (Guruharsha et al., 2011) Ubc12 - CG7675 experimental knowledge based (Guruharsha et al., 2011) Ubc12 - Df31 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Ubc12 - FK506-bp2 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Ubc12 - Uba2 experimental knowledge based (Guruharsha et al., 2011) Ubc12 - regucalcin anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23)
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions Ubc12 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 64336 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0035853 DroID - A comprehensive database of gene and protein interactions. • FBgn0035853 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 38916 SignaLink - A protein-protein and protein-miRNA interaction database with multi-layered structure and multiple confidence scores. • Q9VSF3
Orthologs
OrthoDB Orthologs (35) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6MGSTT Dipteran inclusive ortholog search EOG6DZ24F Insect inclusive ortholog search EOG6M64DV Arthropod inclusive ortholog search EOG6H9W2R Metazoa inclusive ortholog search EOG6H1PQD
Orthologs in Drosophila Species (EOG6MGSTT)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\Ubc12     Drosophila simulans   Dsim\GD13010 Y   Drosophila sechellia   Dsec\GM24960 Y   Drosophila erecta   Dere\GG15103 Y   Drosophila yakuba   Dyak\GE21328 Y   Drosophila ananassae   Dana\GF24700 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA20305 Y   Drosophila persimilis   Dper\GL22563 Y   Drosophila willistoni   Dwil\GK10814 Y   Drosophila virilis   Dvir\GJ12887 Y   Drosophila mojavensis   Dmoj\GI16632 Y   Drosophila grimshawi   Dgri\GH15981 Y
Orthologs in non-Drosophila Dipterans (EOG6DZ24F)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL009026   Anopheles gambiae Malaria mosquito  Agam\AGAP005916   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ007408
Orthologs in non-Dipteran Insects (EOG6M64DV)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\LOC409225   Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG016437   Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH14189   Atta cephalotes Leafcutter ant  Acep\ACEP10021   Camponotus floridanus Florida carpenter ant  Cflo\CFLO22861   Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL23255   Linepithema humile Argentine ant  Lhum\LH10585   Pogonomyrmex barbatus Red harvester ant  Pbar\PB18742   Solenopsis invicta Red fire ant  Sinv\SINV21272   Acyrthosiphon pisum Pea aphid  Apim\ACYPI002132   Bombyx mori Silkmoth  Bmor\BGIBMGA007862   Pediculus humanus Human body louse  Phum\PHUM581720   Tribolium castaneum Red flour beetle  Tcas\TC003234
Orthologs in non-Insect Arthropods (EOG6H9W2R)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\ZZEF1   Ixodes scapularis Deer tick  Isca\ISCW011884
Orthologs in non-Arthropod Metazoa (EOG6H1PQD)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_004487gn   Xenopus tropicalis Western clawed frog  Xtro\ube2m   Mus musculus House mouse  Mmus\Ube2m   Rattus norvegicus Norway rat  Rnor\Ube2m   Homo sapiens Human  Hsap\UBE2M
Human Orthologs (1)
Gene OMIM HGNC Hsap\UBE2M
AAA Orthologs (11) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD13010 Drosophila sechellia Dsec\GM24960 Drosophila erecta Dere\GG15103 Drosophila yakuba Dyak\GE21328 Drosophila ananassae Dana\GF24700 Drosophila pseudoobscura pseudoobscura Dpse\GA20305 Drosophila persimilis Dper\GL22563 Drosophila willistoni Dwil\GK10814 Drosophila virilis Dvir\GJ12887 Drosophila mojavensis Dmoj\GI16632 Drosophila grimshawi Dgri\GH15981
Stocks & Reagents
Stocks Listed in FlyBase ( 8 )
Bloomington	30602 y1 w*; Mi{MIC}Ubc12MI00049/TM6B, Tb1 22589 y1 w67c23; P{EPgy2}Ubc12EY22840/TM3, Sb1 Ser1 16178 y1 w1118; PBac{5HPw+}Ubc12B238/TM3, Sb1 Ser1
Harvard	- PBac{RB}Ubc12e02842
Kyoto	141316 y* w*; PBac{SAstopDsRed}Ubc12LL04684 P{FRT(whs)}2A P{neoFRT}82B P{Car20y}96E/TM6B, Tb1
VDRC	v100761 P{KK108493}VIE-260B v35219 w1118; P{GD12219}v35219 v35220 w1118; P{GD12219}v35220
Genomic Clones ( 2 )
	BACR06E04 BACR09I19 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 126 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	LD29377
Other clones	DPiM_LD29377 yak-em_CG7375
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	GH24490 LD31519 LD32307 LD34629 LD39205 LP03337 LP15801 RE12066 RE47032 RE47642 RE52464 RE61375 RE72052 RH54590
Other clones	1751 30494 79566 161205 166079 275281 557984 bs29b06 bs70g05 CK01.65D.D9 EC051769 EC052815 EC055171 EK053613 EK123151 EK139348 EK182707 EK209331 EK264930 EK270209 EK303138 EN12750 FGM215E10 FGM308F12 FGM316G04 FGM324A07 RP003009065 RP003033038 RP003035657 RP003050394 RP003075106 RP003086716 RP003099133 RP003140226 RP003141570 RP003142070 RP003146244 RP003157639 RP003176297 RP003186529 RP003195611 RP003198965 RP003204622 RP003207211 RP003211532 RP003214232 RP003219041 RP003248453 RP003256440 RP003264092 RP003265163 RP003270042 RP003271470 RP003276038 RP003278112 RP003279216 RP003280028 RP003287151 RP003287887 RP003293117 RP003303972 RP003304974 RP003307419 RP003309237 RP003314681 RP003315283 RP003318019 RP003321092 RP003324215 RP003330588 RP003331710 RP003333980 RP003335200 RP003342797 RP003343969 RP003345370 RP003346345 RP003350633 RP003357362 RP003397250 RP003436135 RP003436920 RP003438125 RP003454063 RP003456732 RP003471209 RP003486967 RP003492057 RP003493192 RP003493412 RP003501293 RP003513073 RP003519964 RP003525694 RP003525866 RP003527886 RP003544360 RP003547037 RP003551048 RP003553428 RP003559440 RP003573735 RP003581870 RP003596326 RP003641739 RP003644327 RP003647494 RP003668701 RP003680363
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0035853 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 38916
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of	Source for identity of: Ubc12 CG7375 (Du et al., 2011)
Source for database merge of	Source for merge of: CG7375 anon-WO0118547.309 (FlyBase, 1996-)
Additional comments	Source for merge of CG7375 anon-WO0118547.309 was sequence comparison (date:051113). (FlyBase, 1996-)
Other Comments
	Area matching Drosophila EST AI259832. This EST overlaps ESTS AA990765 and has sequence similarity to Human ubiquitin conjugating enzyme 12 gene. Probable intron in gene represented by EST AI259832. (Davies, 2001.3.15)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_139930 NM_001274638 NM_001274639 RefSeq (Proteins) • NP_648187 NP_001261567 NP_001261568 DDBJ / EMBL / GenBank • AA952265 AAF50468 AAM49914 AGB94262 AGB94263 AI259832 AI946646 AW942962 AX094185 AY118545 CZ480615 Entrez Gene - A searchable database of RefSeq genes. • 38916 UniProtKB/Swiss-Prot • Q9VSF3
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Ubiquitin-conjugating enzyme, E2 (IPR000608) Ubiquitin-conjugating enzyme/RWD-like (IPR016135) Ubiquitin-conjugating enzyme, active site (IPR023313) BDGP expression data - Patterns of gene expression in Drosophila embryogenesis • LD29377
Linkouts
	BioGRID - A database of protein and genetic interactions • 64336 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0035853 DroID - A comprehensive database of gene and protein interactions. • FBgn0035853 DRSC - Results from RNAi screens. • FBgn0035853 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0035853 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG7375-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0035853 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 38916 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 38916 modMine - Data generated by the modENCODE project. • FBgn0035853 SignaLink - A protein-protein and protein-miRNA interaction database with multi-layered structure and multiple confidence scores. • Q9VSF3
Synonyms & Secondary IDs ( 6 )
Reported As
Symbol Synonym	anon-WO0118547.309   CG7375 (Du et al., 2011, Broemer et al., 2010, Keleman et al., 2009.8.5, Michelle et al., 2009, Yi et al., 2007, Tomancak et al., 2007, Japanese National Institute of Genetics, 2012.5.21, Gurudatta et al., 2012) dUbc12 (Du et al., 2011) Ubc12   UbcD12 (Broemer et al., 2010)
Name Synonym	Ubiquitin conjugating enzyme 12
Secondary FlyBase IDs
	FBgn0062104
References ( 32 )
Generate a list of	All references relating to this gene ( 32 )
List References by type	Research paper  ( 6 ) Supplementary material  ( 5 ) Personal communication to FlyBase  ( 12 ) FlyBase analysis  ( 4 ) Stock list  ( 1 ) Patent  ( 1 ) DNA/RNA sequence record  ( 1 ) Website  ( 1 ) Curated genome annotation  ( 1 )
Recent research papers ( 2 )
	Gurudatta et al., 2012, Dev. Biol. 369(1): 124--132 The BEAF insulator regulates genes involved in cell polarity and neoplastic growth. [FBrf0219796] Du et al., 2011, PLoS ONE 6(9): e24168 In Vivo RNAi Screen Reveals Neddylation Genes as Novel Regulators of Hedgehog Signaling. [FBrf0215574] Show all research papers ...