Ubc12
Please see the JBrowse view of Dmel\UbcE2M for information on other features
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AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Gene model reviewed during 5.45
Interacts with Uba3.
Both the N-terminal docking peptide and the catalytic core domain must bind the Uba3-Ula1 complex simultaneously for optimal transfer of Nedd8.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\UbcE2M using the Feature Mapper tool.
Comment: maternally deposited
GBrowse - Visual display of RNA-Seq signals
View Dmel\UbcE2M in GBrowse 23-22
3-19.0
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for identity of: Ubc12 CG7375
Source for identity of: UbcE2M Ubc12
Source for merge of: CG7375 anon-WO0118547.309
Originally named 'Ubc12' in FBrf0215574 after human/vertebrate 'Ubc12' , but renamed to 'UbcE2M' to (i) avoid confusion with an extant Ubc naming system where the number after the 'Ubc' prefix reflects the order the Ubc genes were characterized; and (ii) reflect the current human gene symbol (at the HGNC).
Source for merge of CG7375 anon-WO0118547.309 was sequence comparison ( date:051113 ).
Area matching Drosophila EST AI259832. This EST overlaps ESTS AA990765 and has sequence similarity to Human ubiquitin conjugating enzyme 12 gene. Probable intron in gene represented by EST AI259832.
Named 'Ubc12' based on the symbol of the human/vertebrate ortholog.