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Gene Dmel\CG7185

General Information
Symbol	Dmel\CG7185	Species	D. melanogaster
Name		Annotation symbol	CG7185
Feature type	protein_coding_gene	FlyBase ID	FBgn0035872
Gene Model Status	Current	Stock availability	5 publicly available
Genomic Location
Chromosome (arm)	3L	Recombination map
Cytogenetic map	66C5-66C6	Sequence location	3L:8,303,593..8,308,602 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG7185 (FBgn0035872). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: mRNA binding. There is experimental evidence that it is involved in the biological process: regulation of alternative mRNA splicing, via spliceosome. 8 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Nucleotide-binding, alpha-beta plait; RNA recognition motif domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderate expression. Peak expression observed within 00-12 hour embryonic stages. Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: larval central nervous system, adult ovary. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult spermathecae, adult male reproductive system, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1635863_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG7185. Gene sequence location is 3L:8303593..8308602.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 66C5-66C6   Limits computationally determined from genome sequence between P{lacW}l(3)L0139L0139 and P{PZ}Gug03928&P{EP}CG6745EP595b
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG7185 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.45 Low-frequency RNA-seq exon junction(s) not annotated.
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG7185-RA FBtr0076710  NM_139949   2862   652 CG7185-RB FBtr0304628  NM_001259736   2721   605
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG7185-PA   FBpp0076433   71.1   652   10.13     NP_648206   AAF50445 CG7185-PB   FBpp0293170   66.1   605   9.86     NP_001246665   AFH04336
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • RNA recognition motif domain (IPR000504) Nucleotide-binding, alpha-beta plait (IPR012677)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA263810   AA391259   AA438580   AA438644   AA438668   AA539899   AA817206   AA817406   AA820676   AA941212   AA941220   AA941735   AA941835   AA942347   AA942592   AA950086   AA950673   AA950841   AA952292   AA979450   AE014296 AAF50445   AE014296 AFH04336   AI258043   AI258163   AI455598   AI515425   AI519046   AI531650   AI535018   AI543676   AW942723   AY058563 AAL13792   BF495441   BG638441   BG641392   BI164195   BI169106   BI170421   BI171866   BI212273   BI216584   BI216871   BI230328   BI230869   BI233040   BI233046   BI233171   BI233254   BI236240   BI239671   BI357608   BI361577   BI363571   BI363737   BI365888   BI366036   BI367596   BI368859   BI371539   BI372919   BI373134   BI486438   BI486541   BI486734   BI578620   BI578890   BI579315   BI579492   BI581409   BI581433   BI588046   BI589396   BI611058   BI635019   BI635039   BI640687   CK131732   CK658118   CK659382   CK662335   CO153369   CO191057   CO272155   CO276768   CO279857   CO280111   CO283986   CO291569   CO328210   CO328708   CO328902   CO329216   CO330461   CZ482226   CZ482227   EC069574   EC072535   EC073247   EC073616   EC090340   EC209208   EC212363   EC220519   EC242019   EC242267   EC259820   EC265455   EV595195   GH748451   GH749397   GH751075   GH752618   GH753280   GH754738   GH755099   GH755146   GH758215   GH758586   GH759501   GH759503   GH759806   GH760825   GH770149   GH770418   GH771950   GH775931   GH779051   GH781183   GH785636   GH786271   GH787237   GH791042   GH793092   GH800461   GH800686   GH800987   GH802150   GH802677   GH803988   GH805477   GH807841   GH808615   GH811604   GH812614   GH814135   GH816074   GH817155   GH819693   GH821643   GH824091   GH827442   GH830607   GH831232   GH833006   GH833973   GH836010   GH838092   GH838593   GH838954   GH840290   GH840419   GH840903   GH842244   GH842434   GH844575   GH848406   GH850156   GH850251   GH852586   GH853474   GH857379   GH857888   GH858063   GH859066   GH861596   GH861956   GH862707   GH864131   GH865504   GH865646   GH867829   GH869729   GH869791   GH873202   GH874464   GH881059   GH882608   GH887213   GH887644   GH888992   GH889756   GH891594   GH897597   GH900592   GH901580   GH902062   GH903974   GH906426   GH906884   GH908140   GH911381   GH912275   GH912506   GH914741   GH916187   GH918038   GH918735   GH919419   GH921911   GH923698   GH923785   GH924581   GH929494   GH932777   GH934271   GH935882   GH937533   GH938677
UniProtKB/Swiss-Prot	Q9VSH4
UniProtKB/TrEMBL
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
in situ Stage Tissue/Position (including subcellular localization) Reference embryonic stage 1 -- 3   organism   (Fisher et al., 2012) Comment:maternally deposited embryonic stage 4 -- 6   organism | ubiquitous   (Fisher et al., 2012) embryonic stage 7 -- 8   organism | faint & ubiquitous   (Fisher et al., 2012) organism | ubiquitous   (Fisher et al., 2012) embryonic stage 9 -- 10   organism | faint & ubiquitous   (Fisher et al., 2012) organism | ubiquitous   (Fisher et al., 2012) embryonic stage 11 -- 12   anterior midgut primordium   (Fisher et al., 2012) central brain primordium   (Fisher et al., 2012) organism | faint & ubiquitous   (Fisher et al., 2012) organism | ubiquitous   (Fisher et al., 2012) posterior midgut primordium   (Fisher et al., 2012) ventral nerve cord primordium   (Fisher et al., 2012) embryonic stage 13 -- 16   embryonic brain   (Fisher et al., 2012) embryonic/larval nervous system   (Fisher et al., 2012) gonad   (Fisher et al., 2012) ventral nerve cord   (Fisher et al., 2012)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: larval central nervous system, adult ovary. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult spermathecae, adult male reproductive system, larval/adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    919.7 Larval Midgut    128.4 Larval Hindgut    285.6 Larval Malpighian Tubules    269.8 Larval Fat Body    231.1 Larval Salivary Gland    416.9 Larval Trachea    374.675 Larval Carcass    326.025 Adult Head    220.9 Adult Eye    226.975 Adult Brain    349.1 Adult Thoracic-Abdominal Ganglion    337.3 Adult Crop    224.1 Adult Midgut    146.8 Adult Hindgut    221.5 Adult Malpighian Tubules    167.1 Adult Fat Body    190.5 Adult Salivary Gland    226.5 Adult Heart    182.85 Adult VirginFemale Spermatheca    239.7 Adult InseminatedFemale Spermatheca    254.9 Adult Ovary    936.5 Adult Testis    125.7 Adult Male Accessory Gland    236.4 Adult Carcass    157.2 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System  (919.7) Larval Midgut    128.4 Larval Hindgut    285.6 Larval Malpighian Tubules    269.8 Larval Fat Body    231.1 Larval Salivary Gland    416.9 Larval Trachea    374.675 Larval Carcass    326.025 Adult Head    220.9 Adult Eye    226.975 Adult Brain    349.1 Adult Thoracic-Abdominal Ganglion    337.3 Adult Crop    224.1 Adult Midgut    146.8 Adult Hindgut    221.5 Adult Malpighian Tubules    167.1 Adult Fat Body    190.5 Adult Salivary Gland    226.5 Adult Heart    182.85 Adult VirginFemale Spermatheca    239.7 Adult InseminatedFemale Spermatheca    254.9 Adult Ovary  (936.5) Adult Testis    125.7 Adult Male Accessory Gland    236.4 Adult Carcass    157.2 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    919.7 Larval Midgut    128.4 Larval Hindgut    285.6 Larval Malpighian Tubules    269.8 Larval Fat Body    231.1 Larval Salivary Gland    416.9 Larval Trachea    374.675 Larval Carcass    326.025 Adult Head    220.9 Adult Eye    226.975 Adult Brain    349.1 Adult Thoracic-Abdominal Ganglion    337.3 Adult Crop    224.1 Adult Midgut    146.8 Adult Hindgut    221.5 Adult Malpighian Tubules    167.1 Adult Fat Body    190.5 Adult Salivary Gland    226.5 Adult Heart    182.85 Adult VirginFemale Spermatheca    239.7 Adult InseminatedFemale Spermatheca    254.9 Adult Ovary    936.5 Adult Testis    125.7 Adult Male Accessory Gland    236.4 Adult Carcass    157.2 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    919.7 Larval Midgut    128.4 Larval Hindgut    285.6 Larval Malpighian Tubules    269.8 Larval Fat Body    231.1 Larval Salivary Gland    416.9 Larval Trachea    374.675 Larval Carcass    326.025 Adult Head    220.9 Adult Eye    226.975 Adult Brain    349.1 Adult Thoracic-Abdominal Ganglion    337.3 Adult Crop    224.1 Adult Midgut    146.8 Adult Hindgut    221.5 Adult Malpighian Tubules    167.1 Adult Fat Body    190.5 Adult Salivary Gland    226.5 Adult Heart    182.85 Adult VirginFemale Spermatheca    239.7 Adult InseminatedFemale Spermatheca    254.9 Adult Ovary    936.5 Adult Testis    125.7 Adult Male Accessory Gland    236.4 Adult Carcass    157.2 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    919.7 Larval Midgut    128.4 Larval Hindgut    285.6 Larval Malpighian Tubules    269.8 Larval Fat Body    231.1 Larval Salivary Gland    416.9 Larval Trachea    374.675 Larval Carcass    326.025 Adult Head    220.9 Adult Eye    226.975 Adult Brain    349.1 Adult Thoracic-Abdominal Ganglion    337.3 Adult Crop    224.1 Adult Midgut    146.8 Adult Hindgut    221.5 Adult Malpighian Tubules    167.1 Adult Fat Body    190.5 Adult Salivary Gland    226.5 Adult Heart    182.85 Adult VirginFemale Spermatheca    239.7 Adult InseminatedFemale Spermatheca    254.9 Adult Ovary    936.5 Adult Testis    125.7 Adult Male Accessory Gland    236.4 Adult Carcass    157.2 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System  (919.7) Larval Midgut    128.4 Larval Hindgut    285.6 Larval Malpighian Tubules    269.8 Larval Fat Body    231.1 Larval Salivary Gland    416.9 Larval Trachea    374.675 Larval Carcass    326.025 Adult Head    220.9 Adult Eye    226.975 Adult Brain    349.1 Adult Thoracic-Abdominal Ganglion    337.3 Adult Crop    224.1 Adult Midgut    146.8 Adult Hindgut    221.5 Adult Malpighian Tubules    167.1 Adult Fat Body    190.5 Adult Salivary Gland    226.5 Adult Heart    182.85 Adult VirginFemale Spermatheca    239.7 Adult InseminatedFemale Spermatheca    254.9 Adult Ovary  (936.5) Adult Testis    125.7 Adult Male Accessory Gland    236.4 Adult Carcass    157.2 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    919.7 Larval Midgut    128.4 Larval Hindgut    285.6 Larval Malpighian Tubules    269.8 Larval Fat Body    231.1 Larval Salivary Gland    416.9 Larval Trachea    374.675 Larval Carcass    326.025 Adult Head    220.9 Adult Eye    226.975 Adult Brain    349.1 Adult Thoracic-Abdominal Ganglion    337.3 Adult Crop    224.1 Adult Midgut    146.8 Adult Hindgut    221.5 Adult Malpighian Tubules    167.1 Adult Fat Body    190.5 Adult Salivary Gland    226.5 Adult Heart    182.85 Adult VirginFemale Spermatheca    239.7 Adult InseminatedFemale Spermatheca    254.9 Adult Ovary    936.5 Adult Testis    125.7 Adult Male Accessory Gland    236.4 Adult Carcass    157.2 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    919.7 Larval Midgut    128.4 Larval Hindgut    285.6 Larval Malpighian Tubules    269.8 Larval Fat Body    231.1 Larval Salivary Gland    416.9 Larval Trachea    374.675 Larval Carcass    326.025 Adult Head    220.9 Adult Eye    226.975 Adult Brain    349.1 Adult Thoracic-Abdominal Ganglion    337.3 Adult Crop    224.1 Adult Midgut    146.8 Adult Hindgut    221.5 Adult Malpighian Tubules    167.1 Adult Fat Body    190.5 Adult Salivary Gland    226.5 Adult Heart    182.85 Adult VirginFemale Spermatheca    239.7 Adult InseminatedFemale Spermatheca    254.9 Adult Ovary    936.5 Adult Testis    125.7 Adult Male Accessory Gland    236.4 Adult Carcass    157.2 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    220.9   NA  Eye    226.975   NA  Brain    349.1   919.7  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    337.3   NA  Crop    224.1   128.4  Midgut    146.8   285.6  Hindgut    221.5   269.8  Malpighian Tubules    167.1   231.1  Fat Body    190.5   416.9  Salivary Gland    226.5   NA  Heart    182.85   374.675  Trachea    NA   NA  VirginFemale Spermatheca    239.7   NA  InseminatedFemale Spermatheca    254.9   NA  Ovary    936.5   NA  Testis    125.7   NA  Male Accessory Gland    236.4   326.025  Carcass    157.2 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    65 central nervous system, larvae L3    90 central nervous system, pupae P8    43 head, virgin 1-day female    19 head, virgin 4-day female    17 head, virgin 20-day female    15 head, mated 1-day female    17 head, mated 4-day female    13 head, mated 20-day female    12 head, mated 1-day male    24 head, mated 4-day male    20 head, mated 20-day male    24 salivary gland, larvae L3 wandering    3 salivary gland, white prepupae    7 digestive system, larvae L3 wandering    12 digestive system, 1-day adult    14 digestive system, 4-day adult    17 digestive system, 20-day adult    16 fat body, larvae L3 wandering    8 fat body, white prepupae    18 fat body, pupae P8    32 carcass, larvae L3 wandering    49 carcass, 1-day adult    11 carcass, 4-day adult    16 carcass, 20-day adult    14 ovary, virgin 4-day female    120 ovary, mated 4-day female    124 testis, mated 4-day male    24 accessory gland, mated 4-day male    12 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (65) central nervous system, larvae L3  (90) central nervous system, pupae P8  (43) head, virgin 1-day female    19 head, virgin 4-day female    17 head, virgin 20-day female    15 head, mated 1-day female    17 head, mated 4-day female    13 head, mated 20-day female    12 head, mated 1-day male    24 head, mated 4-day male    20 head, mated 20-day male    24 salivary gland, larvae L3 wandering    3 salivary gland, white prepupae    7 digestive system, larvae L3 wandering    12 digestive system, 1-day adult    14 digestive system, 4-day adult    17 digestive system, 20-day adult    16 fat body, larvae L3 wandering    8 fat body, white prepupae    18 fat body, pupae P8  (32) carcass, larvae L3 wandering  (49) carcass, 1-day adult    11 carcass, 4-day adult    16 carcass, 20-day adult    14 ovary, virgin 4-day female  (120) ovary, mated 4-day female  (124) testis, mated 4-day male    24 accessory gland, mated 4-day male    12 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    65 central nervous system, larvae L3    90 central nervous system, pupae P8    43 head, virgin 1-day female    19 head, virgin 4-day female    17 head, virgin 20-day female    15 head, mated 1-day female    17 head, mated 4-day female    13 head, mated 20-day female    12 head, mated 1-day male    24 head, mated 4-day male    20 head, mated 20-day male    24 salivary gland, larvae L3 wandering    3 salivary gland, white prepupae    7 digestive system, larvae L3 wandering    12 digestive system, 1-day adult    14 digestive system, 4-day adult    17 digestive system, 20-day adult    16 fat body, larvae L3 wandering    8 fat body, white prepupae    18 fat body, pupae P8    32 carcass, larvae L3 wandering    49 carcass, 1-day adult    11 carcass, 4-day adult    16 carcass, 20-day adult    14 ovary, virgin 4-day female  (120) ovary, mated 4-day female  (124) testis, mated 4-day male    24 accessory gland, mated 4-day male    12 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    65 central nervous system, larvae L3    90 central nervous system, pupae P8    43 head, virgin 1-day female    19 head, virgin 4-day female    17 head, virgin 20-day female    15 head, mated 1-day female    17 head, mated 4-day female    13 head, mated 20-day female    12 head, mated 1-day male    24 head, mated 4-day male    20 head, mated 20-day male    24 salivary gland, larvae L3 wandering    3 salivary gland, white prepupae    7 digestive system, larvae L3 wandering    12 digestive system, 1-day adult    14 digestive system, 4-day adult    17 digestive system, 20-day adult    16 fat body, larvae L3 wandering    8 fat body, white prepupae    18 fat body, pupae P8    32 carcass, larvae L3 wandering    49 carcass, 1-day adult    11 carcass, 4-day adult    16 carcass, 20-day adult    14 ovary, virgin 4-day female    120 ovary, mated 4-day female    124 testis, mated 4-day male    24 accessory gland, mated 4-day male    12 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    65 central nervous system, larvae L3    90 central nervous system, pupae P8    43 head, virgin 1-day female    19 head, virgin 4-day female    17 head, virgin 20-day female    15 head, mated 1-day female    17 head, mated 4-day female    13 head, mated 20-day female    12 head, mated 1-day male    24 head, mated 4-day male    20 head, mated 20-day male    24 salivary gland, larvae L3 wandering    3 salivary gland, white prepupae    7 digestive system, larvae L3 wandering    12 digestive system, 1-day adult    14 digestive system, 4-day adult    17 digestive system, 20-day adult    16 fat body, larvae L3 wandering    8 fat body, white prepupae    18 fat body, pupae P8    32 carcass, larvae L3 wandering    49 carcass, 1-day adult    11 carcass, 4-day adult    16 carcass, 20-day adult    14 ovary, virgin 4-day female    120 ovary, mated 4-day female    124 testis, mated 4-day male    24 accessory gland, mated 4-day male    12 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (65) central nervous system, larvae L3  (90) central nervous system, pupae P8  (43) head, virgin 1-day female    19 head, virgin 4-day female    17 head, virgin 20-day female    15 head, mated 1-day female    17 head, mated 4-day female    13 head, mated 20-day female    12 head, mated 1-day male    24 head, mated 4-day male    20 head, mated 20-day male    24 salivary gland, larvae L3 wandering    3 salivary gland, white prepupae    7 digestive system, larvae L3 wandering    12 digestive system, 1-day adult    14 digestive system, 4-day adult    17 digestive system, 20-day adult    16 fat body, larvae L3 wandering    8 fat body, white prepupae    18 fat body, pupae P8  32 carcass, larvae L3 wandering  (49) carcass, 1-day adult    11 carcass, 4-day adult    16 carcass, 20-day adult    14 ovary, virgin 4-day female  (120) ovary, mated 4-day female  (124) testis, mated 4-day male    24 accessory gland, mated 4-day male    12 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    65 central nervous system, larvae L3    90 central nervous system, pupae P8    43 head, virgin 1-day female    19 head, virgin 4-day female    17 head, virgin 20-day female    15 head, mated 1-day female    17 head, mated 4-day female    13 head, mated 20-day female    12 head, mated 1-day male    24 head, mated 4-day male    20 head, mated 20-day male    24 salivary gland, larvae L3 wandering    3 salivary gland, white prepupae    7 digestive system, larvae L3 wandering    12 digestive system, 1-day adult    14 digestive system, 4-day adult    17 digestive system, 20-day adult    16 fat body, larvae L3 wandering    8 fat body, white prepupae    18 fat body, pupae P8    32 carcass, larvae L3 wandering    49 carcass, 1-day adult    11 carcass, 4-day adult    16 carcass, 20-day adult    14 ovary, virgin 4-day female  120 ovary, mated 4-day female  124 testis, mated 4-day male    24 accessory gland, mated 4-day male    12 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    65 central nervous system, larvae L3    90 central nervous system, pupae P8    43 head, virgin 1-day female    19 head, virgin 4-day female    17 head, virgin 20-day female    15 head, mated 1-day female    17 head, mated 4-day female    13 head, mated 20-day female    12 head, mated 1-day male    24 head, mated 4-day male    20 head, mated 20-day male    24 salivary gland, larvae L3 wandering    3 salivary gland, white prepupae    7 digestive system, larvae L3 wandering    12 digestive system, 1-day adult    14 digestive system, 4-day adult    17 digestive system, 20-day adult    16 fat body, larvae L3 wandering    8 fat body, white prepupae    18 fat body, pupae P8    32 carcass, larvae L3 wandering    49 carcass, 1-day adult    11 carcass, 4-day adult    16 carcass, 20-day adult    14 ovary, virgin 4-day female    120 ovary, mated 4-day female    124 testis, mated 4-day male    24 accessory gland, mated 4-day male    12 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderate expression. Peak expression observed within 00-12 hour embryonic stages. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    174 embryo 02-04hr    171 embryo 04-06hr    164 embryo 06-08hr    148 embryo 08-10hr    115 embryo 10-12hr    94 embryo 12-14hr    60 embryo 14-16hr    61 embryo 16-18hr    39 embryo 18-20hr    26 embryo 20-22hr    21 embryo 22-24hr    19 larva L1    36 larva L2    36 larva L3 12hr old    28 larva L3 puffstage 1-2    25 larva L3 puffstage 3-6    37 larva L3 puffstage 7-9    39 white prepupae new    42 white prepupae 12hr    45 white prepupae 24hr    58 pupae 2d postWPP    33 pupae 3d postWPP    16 pupae 4d postWPP    15 adult male 01day    17 adult male 05day    21 adult male 30day    20 adult female 01day    56 adult female 05day    89 adult female 30day    93 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (174) embryo 02-04hr  (171) embryo 04-06hr  (164) embryo 06-08hr  (148) embryo 08-10hr  (115) embryo 10-12hr  (94) embryo 12-14hr  (60) embryo 14-16hr  (61) embryo 16-18hr  (39) embryo 18-20hr  26 embryo 20-22hr    21 embryo 22-24hr    19 larva L1  (36) larva L2  (36) larva L3 12hr old  (28) larva L3 puffstage 1-2    25 larva L3 puffstage 3-6  (37) larva L3 puffstage 7-9  (39) white prepupae new  (42) white prepupae 12hr  (45) white prepupae 24hr  (58) pupae 2d postWPP  (33) pupae 3d postWPP    16 pupae 4d postWPP    15 adult male 01day    17 adult male 05day    21 adult male 30day    20 adult female 01day  (56) adult female 05day  (89) adult female 30day  (93) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr  (174) embryo 02-04hr  (171) embryo 04-06hr  (164) embryo 06-08hr  (148) embryo 08-10hr  (115) embryo 10-12hr    94 embryo 12-14hr    60 embryo 14-16hr    61 embryo 16-18hr    39 embryo 18-20hr    26 embryo 20-22hr    21 embryo 22-24hr    19 larva L1    36 larva L2    36 larva L3 12hr old    28 larva L3 puffstage 1-2    25 larva L3 puffstage 3-6    37 larva L3 puffstage 7-9    39 white prepupae new    42 white prepupae 12hr    45 white prepupae 24hr    58 pupae 2d postWPP    33 pupae 3d postWPP    16 pupae 4d postWPP    15 adult male 01day    17 adult male 05day    21 adult male 30day    20 adult female 01day    56 adult female 05day    89 adult female 30day    93 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    174 embryo 02-04hr    171 embryo 04-06hr    164 embryo 06-08hr    148 embryo 08-10hr    115 embryo 10-12hr    94 embryo 12-14hr    60 embryo 14-16hr    61 embryo 16-18hr    39 embryo 18-20hr    26 embryo 20-22hr    21 embryo 22-24hr    19 larva L1    36 larva L2    36 larva L3 12hr old    28 larva L3 puffstage 1-2    25 larva L3 puffstage 3-6    37 larva L3 puffstage 7-9    39 white prepupae new    42 white prepupae 12hr    45 white prepupae 24hr    58 pupae 2d postWPP    33 pupae 3d postWPP    16 pupae 4d postWPP    15 adult male 01day    17 adult male 05day    21 adult male 30day    20 adult female 01day    56 adult female 05day    89 adult female 30day    93 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    174 embryo 02-04hr    171 embryo 04-06hr    164 embryo 06-08hr    148 embryo 08-10hr    115 embryo 10-12hr    94 embryo 12-14hr    60 embryo 14-16hr    61 embryo 16-18hr    39 embryo 18-20hr    26 embryo 20-22hr    21 embryo 22-24hr    19 larva L1    36 larva L2    36 larva L3 12hr old    28 larva L3 puffstage 1-2    25 larva L3 puffstage 3-6    37 larva L3 puffstage 7-9    39 white prepupae new    42 white prepupae 12hr    45 white prepupae 24hr    58 pupae 2d postWPP    33 pupae 3d postWPP    16 pupae 4d postWPP    15 adult male 01day    17 adult male 05day    21 adult male 30day    20 adult female 01day    56 adult female 05day    89 adult female 30day    93 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (174) embryo 02-04hr  (171) embryo 04-06hr  (164) embryo 06-08hr  (148) embryo 08-10hr  (115) embryo 10-12hr  (94) embryo 12-14hr  (60) embryo 14-16hr  (61) embryo 16-18hr  (39) embryo 18-20hr  26 embryo 20-22hr    21 embryo 22-24hr    19 larva L1  (36) larva L2  (36) larva L3 12hr old  28 larva L3 puffstage 1-2    25 larva L3 puffstage 3-6  (37) larva L3 puffstage 7-9  (39) white prepupae new  (42) white prepupae 12hr  (45) white prepupae 24hr  (58) pupae 2d postWPP  (33) pupae 3d postWPP    16 pupae 4d postWPP    15 adult male 01day    17 adult male 05day    21 adult male 30day    20 adult female 01day  (56) adult female 05day  (89) adult female 30day  (93) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr  (174) embryo 02-04hr  (171) embryo 04-06hr  (164) embryo 06-08hr  (148) embryo 08-10hr  115 embryo 10-12hr    94 embryo 12-14hr    60 embryo 14-16hr    61 embryo 16-18hr    39 embryo 18-20hr    26 embryo 20-22hr    21 embryo 22-24hr    19 larva L1    36 larva L2    36 larva L3 12hr old    28 larva L3 puffstage 1-2    25 larva L3 puffstage 3-6    37 larva L3 puffstage 7-9    39 white prepupae new    42 white prepupae 12hr    45 white prepupae 24hr    58 pupae 2d postWPP    33 pupae 3d postWPP    16 pupae 4d postWPP    15 adult male 01day    17 adult male 05day    21 adult male 30day    20 adult female 01day    56 adult female 05day    89 adult female 30day    93 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    174 embryo 02-04hr    171 embryo 04-06hr    164 embryo 06-08hr    148 embryo 08-10hr    115 embryo 10-12hr    94 embryo 12-14hr    60 embryo 14-16hr    61 embryo 16-18hr    39 embryo 18-20hr    26 embryo 20-22hr    21 embryo 22-24hr    19 larva L1    36 larva L2    36 larva L3 12hr old    28 larva L3 puffstage 1-2    25 larva L3 puffstage 3-6    37 larva L3 puffstage 7-9    39 white prepupae new    42 white prepupae 12hr    45 white prepupae 24hr    58 pupae 2d postWPP    33 pupae 3d postWPP    16 pupae 4d postWPP    15 adult male 01day    17 adult male 05day    21 adult male 30day    20 adult female 01day    56 adult female 05day    89 adult female 30day    93 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    92 Schneider line 2 Sg4    101 embryonic 1182-4H    77 embryonic GM2    51 embryonic Kc167    70 embryonic S1    82 embryonic S3    96 leg disc CME L1    85 wing disc CME-W2    66 wing disc ML-DmD8    69 wing disc ML-DmD9    82 wing disc ML-DmD16-c3    80 wing disc ML-DmD21    93 wing disc ML-DmD32    65 haltere disc ML-DmD17-c3    98 eye-antennal disc ML-DmD11    74 antennal disc ML-DmD20-c5    83 mixed discs ML-DmD4-c1    103 CNS ML-DmBG1-c1    76 CNS ML-DmBG2-c2    68 tumorous blood cells mbn2    78 ovary fGS/OSS    59 ovary OSC    50 ovary OSS    50 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (92) Schneider line 2 Sg4  (101) embryonic 1182-4H  (77) embryonic GM2  (51) embryonic Kc167  (70) embryonic S1  (82) embryonic S3  (96) leg disc CME L1  (85) wing disc CME-W2  (66) wing disc ML-DmD8  (69) wing disc ML-DmD9  (82) wing disc ML-DmD16-c3  (80) wing disc ML-DmD21  (93) wing disc ML-DmD32  (65) haltere disc ML-DmD17-c3  (98) eye-antennal disc ML-DmD11  (74) antennal disc ML-DmD20-c5  (83) mixed discs ML-DmD4-c1  (103) CNS ML-DmBG1-c1  (76) CNS ML-DmBG2-c2  (68) tumorous blood cells mbn2  (78) ovary fGS/OSS  (59) ovary OSC  (50) ovary OSS  (50) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    92 Schneider line 2 Sg4  101 embryonic 1182-4H    77 embryonic GM2    51 embryonic Kc167    70 embryonic S1    82 embryonic S3    96 leg disc CME L1    85 wing disc CME-W2    66 wing disc ML-DmD8    69 wing disc ML-DmD9    82 wing disc ML-DmD16-c3    80 wing disc ML-DmD21    93 wing disc ML-DmD32    65 haltere disc ML-DmD17-c3    98 eye-antennal disc ML-DmD11    74 antennal disc ML-DmD20-c5    83 mixed discs ML-DmD4-c1  103 CNS ML-DmBG1-c1    76 CNS ML-DmBG2-c2    68 tumorous blood cells mbn2    78 ovary fGS/OSS    59 ovary OSC    50 ovary OSS    50 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    92 Schneider line 2 Sg4    101 embryonic 1182-4H    77 embryonic GM2    51 embryonic Kc167    70 embryonic S1    82 embryonic S3    96 leg disc CME L1    85 wing disc CME-W2    66 wing disc ML-DmD8    69 wing disc ML-DmD9    82 wing disc ML-DmD16-c3    80 wing disc ML-DmD21    93 wing disc ML-DmD32    65 haltere disc ML-DmD17-c3    98 eye-antennal disc ML-DmD11    74 antennal disc ML-DmD20-c5    83 mixed discs ML-DmD4-c1    103 CNS ML-DmBG1-c1    76 CNS ML-DmBG2-c2    68 tumorous blood cells mbn2    78 ovary fGS/OSS    59 ovary OSC    50 ovary OSS    50 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    92 Schneider line 2 Sg4    101 embryonic 1182-4H    77 embryonic GM2    51 embryonic Kc167    70 embryonic S1    82 embryonic S3    96 leg disc CME L1    85 wing disc CME-W2    66 wing disc ML-DmD8    69 wing disc ML-DmD9    82 wing disc ML-DmD16-c3    80 wing disc ML-DmD21    93 wing disc ML-DmD32    65 haltere disc ML-DmD17-c3    98 eye-antennal disc ML-DmD11    74 antennal disc ML-DmD20-c5    83 mixed discs ML-DmD4-c1    103 CNS ML-DmBG1-c1    76 CNS ML-DmBG2-c2    68 tumorous blood cells mbn2    78 ovary fGS/OSS    59 ovary OSC    50 ovary OSS    50 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (92) Schneider line 2 Sg4  (101) embryonic 1182-4H  (77) embryonic GM2  (51) embryonic Kc167  (70) embryonic S1  (82) embryonic S3  (96) leg disc CME L1  (85) wing disc CME-W2  (66) wing disc ML-DmD8  (69) wing disc ML-DmD9  (82) wing disc ML-DmD16-c3  (80) wing disc ML-DmD21  (93) wing disc ML-DmD32  (65) haltere disc ML-DmD17-c3  (98) eye-antennal disc ML-DmD11  (74) antennal disc ML-DmD20-c5  (83) mixed discs ML-DmD4-c1  (103) CNS ML-DmBG1-c1  (76) CNS ML-DmBG2-c2  (68) tumorous blood cells mbn2  (78) ovary fGS/OSS  (59) ovary OSC  (50) ovary OSS  (50) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    92 Schneider line 2 Sg4  101 embryonic 1182-4H    77 embryonic GM2    51 embryonic Kc167    70 embryonic S1    82 embryonic S3    96 leg disc CME L1    85 wing disc CME-W2    66 wing disc ML-DmD8    69 wing disc ML-DmD9    82 wing disc ML-DmD16-c3    80 wing disc ML-DmD21    93 wing disc ML-DmD32    65 haltere disc ML-DmD17-c3    98 eye-antennal disc ML-DmD11    74 antennal disc ML-DmD20-c5    83 mixed discs ML-DmD4-c1  103 CNS ML-DmBG1-c1    76 CNS ML-DmBG2-c2    68 tumorous blood cells mbn2    78 ovary fGS/OSS    59 ovary OSC    50 ovary OSS    50 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    92 Schneider line 2 Sg4    101 embryonic 1182-4H    77 embryonic GM2    51 embryonic Kc167    70 embryonic S1    82 embryonic S3    96 leg disc CME L1    85 wing disc CME-W2    66 wing disc ML-DmD8    69 wing disc ML-DmD9    82 wing disc ML-DmD16-c3    80 wing disc ML-DmD21    93 wing disc ML-DmD32    65 haltere disc ML-DmD17-c3    98 eye-antennal disc ML-DmD11    74 antennal disc ML-DmD20-c5    83 mixed discs ML-DmD4-c1    103 CNS ML-DmBG1-c1    76 CNS ML-DmBG2-c2    68 tumorous blood cells mbn2    78 ovary fGS/OSS    59 ovary OSC    50 ovary OSS    50 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    44 cold shock, 4-day adult    33 heat shock, 4-day adult    44 Cadmium 50 mM 6 hrs, larvae L3    23 Cadmium 50 mM 12 hrs, larvae L3    18 Cadmium 50 mM 48 hrs, 4-day adult    47 Cadmium 100 mM 48 hrs, 4-day adult    94 Copper 0.5 mM 12 hrs, larvae L3    34 Copper 15 mM 48 hrs, 4-day adult    47 Zinc 5 mM 12 hrs, larvae L3    23 Zinc 4.5 mM 48 hrs, 4-day adult    27 Ethanol 2.5% 3 hrs, larvae L3    86 Ethanol 5% 3 hrs, larvae L3    17 Ethanol 10% 3 hrs, larvae L3    24 Caffeine 1.5 mg/ml 4 hrs, larvae L3    13 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    83 Caffeine 25 mg/ml 48 hrs, 4-day adult    45 Paraquat 5 mM 48 hrs, 4-day adult    74 Paraquat 10 mM 48 hrs, 4-day adult    59 Rotenone 2 μg 12 hrs, larvae L3    21 Rotenone 8 μg 12 hrs, larvae L3    21 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult  (44) cold shock, 4-day adult  (33) heat shock, 4-day adult  (44) Cadmium 50 mM 6 hrs, larvae L3    23 Cadmium 50 mM 12 hrs, larvae L3    18 Cadmium 50 mM 48 hrs, 4-day adult  (47) Cadmium 100 mM 48 hrs, 4-day adult  (94) Copper 0.5 mM 12 hrs, larvae L3  (34) Copper 15 mM 48 hrs, 4-day adult  (47) Zinc 5 mM 12 hrs, larvae L3    23 Zinc 4.5 mM 48 hrs, 4-day adult  (27) Ethanol 2.5% 3 hrs, larvae L3  (86) Ethanol 5% 3 hrs, larvae L3    17 Ethanol 10% 3 hrs, larvae L3    24 Caffeine 1.5 mg/ml 4 hrs, larvae L3    13 Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (83) Caffeine 25 mg/ml 48 hrs, 4-day adult  (45) Paraquat 5 mM 48 hrs, 4-day adult  (74) Paraquat 10 mM 48 hrs, 4-day adult  (59) Rotenone 2 μg 12 hrs, larvae L3    21 Rotenone 8 μg 12 hrs, larvae L3    21 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    44 cold shock, 4-day adult    33 heat shock, 4-day adult    44 Cadmium 50 mM 6 hrs, larvae L3    23 Cadmium 50 mM 12 hrs, larvae L3    18 Cadmium 50 mM 48 hrs, 4-day adult    47 Cadmium 100 mM 48 hrs, 4-day adult    94 Copper 0.5 mM 12 hrs, larvae L3    34 Copper 15 mM 48 hrs, 4-day adult    47 Zinc 5 mM 12 hrs, larvae L3    23 Zinc 4.5 mM 48 hrs, 4-day adult    27 Ethanol 2.5% 3 hrs, larvae L3    86 Ethanol 5% 3 hrs, larvae L3    17 Ethanol 10% 3 hrs, larvae L3    24 Caffeine 1.5 mg/ml 4 hrs, larvae L3    13 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    83 Caffeine 25 mg/ml 48 hrs, 4-day adult    45 Paraquat 5 mM 48 hrs, 4-day adult    74 Paraquat 10 mM 48 hrs, 4-day adult    59 Rotenone 2 μg 12 hrs, larvae L3    21 Rotenone 8 μg 12 hrs, larvae L3    21 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    44 cold shock, 4-day adult    33 heat shock, 4-day adult    44 Cadmium 50 mM 6 hrs, larvae L3    23 Cadmium 50 mM 12 hrs, larvae L3    18 Cadmium 50 mM 48 hrs, 4-day adult    47 Cadmium 100 mM 48 hrs, 4-day adult    94 Copper 0.5 mM 12 hrs, larvae L3    34 Copper 15 mM 48 hrs, 4-day adult    47 Zinc 5 mM 12 hrs, larvae L3    23 Zinc 4.5 mM 48 hrs, 4-day adult    27 Ethanol 2.5% 3 hrs, larvae L3    86 Ethanol 5% 3 hrs, larvae L3    17 Ethanol 10% 3 hrs, larvae L3    24 Caffeine 1.5 mg/ml 4 hrs, larvae L3    13 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    83 Caffeine 25 mg/ml 48 hrs, 4-day adult    45 Paraquat 5 mM 48 hrs, 4-day adult    74 Paraquat 10 mM 48 hrs, 4-day adult    59 Rotenone 2 μg 12 hrs, larvae L3    21 Rotenone 8 μg 12 hrs, larvae L3    21 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    44 cold shock, 4-day adult    33 heat shock, 4-day adult    44 Cadmium 50 mM 6 hrs, larvae L3    23 Cadmium 50 mM 12 hrs, larvae L3    18 Cadmium 50 mM 48 hrs, 4-day adult    47 Cadmium 100 mM 48 hrs, 4-day adult    94 Copper 0.5 mM 12 hrs, larvae L3    34 Copper 15 mM 48 hrs, 4-day adult    47 Zinc 5 mM 12 hrs, larvae L3    23 Zinc 4.5 mM 48 hrs, 4-day adult    27 Ethanol 2.5% 3 hrs, larvae L3    86 Ethanol 5% 3 hrs, larvae L3    17 Ethanol 10% 3 hrs, larvae L3    24 Caffeine 1.5 mg/ml 4 hrs, larvae L3    13 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    83 Caffeine 25 mg/ml 48 hrs, 4-day adult    45 Paraquat 5 mM 48 hrs, 4-day adult    74 Paraquat 10 mM 48 hrs, 4-day adult    59 Rotenone 2 μg 12 hrs, larvae L3    21 Rotenone 8 μg 12 hrs, larvae L3    21 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult  (44) cold shock, 4-day adult  (33) heat shock, 4-day adult  (44) Cadmium 50 mM 6 hrs, larvae L3    23 Cadmium 50 mM 12 hrs, larvae L3    18 Cadmium 50 mM 48 hrs, 4-day adult  (47) Cadmium 100 mM 48 hrs, 4-day adult  (94) Copper 0.5 mM 12 hrs, larvae L3  (34) Copper 15 mM 48 hrs, 4-day adult  (47) Zinc 5 mM 12 hrs, larvae L3    23 Zinc 4.5 mM 48 hrs, 4-day adult  27 Ethanol 2.5% 3 hrs, larvae L3  (86) Ethanol 5% 3 hrs, larvae L3    17 Ethanol 10% 3 hrs, larvae L3    24 Caffeine 1.5 mg/ml 4 hrs, larvae L3    13 Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (83) Caffeine 25 mg/ml 48 hrs, 4-day adult  (45) Paraquat 5 mM 48 hrs, 4-day adult  (74) Paraquat 10 mM 48 hrs, 4-day adult  (59) Rotenone 2 μg 12 hrs, larvae L3    21 Rotenone 8 μg 12 hrs, larvae L3    21 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    44 cold shock, 4-day adult    33 heat shock, 4-day adult    44 Cadmium 50 mM 6 hrs, larvae L3    23 Cadmium 50 mM 12 hrs, larvae L3    18 Cadmium 50 mM 48 hrs, 4-day adult    47 Cadmium 100 mM 48 hrs, 4-day adult    94 Copper 0.5 mM 12 hrs, larvae L3    34 Copper 15 mM 48 hrs, 4-day adult    47 Zinc 5 mM 12 hrs, larvae L3    23 Zinc 4.5 mM 48 hrs, 4-day adult    27 Ethanol 2.5% 3 hrs, larvae L3    86 Ethanol 5% 3 hrs, larvae L3    17 Ethanol 10% 3 hrs, larvae L3    24 Caffeine 1.5 mg/ml 4 hrs, larvae L3    13 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    83 Caffeine 25 mg/ml 48 hrs, 4-day adult    45 Paraquat 5 mM 48 hrs, 4-day adult    74 Paraquat 10 mM 48 hrs, 4-day adult    59 Rotenone 2 μg 12 hrs, larvae L3    21 Rotenone 8 μg 12 hrs, larvae L3    21 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    44 cold shock, 4-day adult    33 heat shock, 4-day adult    44 Cadmium 50 mM 6 hrs, larvae L3    23 Cadmium 50 mM 12 hrs, larvae L3    18 Cadmium 50 mM 48 hrs, 4-day adult    47 Cadmium 100 mM 48 hrs, 4-day adult    94 Copper 0.5 mM 12 hrs, larvae L3    34 Copper 15 mM 48 hrs, 4-day adult    47 Zinc 5 mM 12 hrs, larvae L3    23 Zinc 4.5 mM 48 hrs, 4-day adult    27 Ethanol 2.5% 3 hrs, larvae L3    86 Ethanol 5% 3 hrs, larvae L3    17 Ethanol 10% 3 hrs, larvae L3    24 Caffeine 1.5 mg/ml 4 hrs, larvae L3    13 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    83 Caffeine 25 mg/ml 48 hrs, 4-day adult    45 Paraquat 5 mM 48 hrs, 4-day adult    74 Paraquat 10 mM 48 hrs, 4-day adult    59 Rotenone 2 μg 12 hrs, larvae L3    21 Rotenone 8 μg 12 hrs, larvae L3    21 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_17 mE1_20_mRNA_expression_cluster_02
External Data & Images
Linkouts	BDGP expression data • LD25239 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0035872 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG7185-RA FlyExpress - Embryonic expression images (BDGP data) • Show all FlyExpress processed images for CG7185 Stages(s) 1-3 Stages(s) 4-6 Stages(s) 9-10 Stages(s) 11-12 Stages(s) 13-16
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable CG7185CC00645 Phenotype manifest in Allele
Classical Alleles ( 4 )
For All Classical Alleles Show
Allele of CG7185 Class Mutagen Stocks Known lesion CG7185CB-6365-3 1 -- CG7185DG14101 P-element activity 1 -- CG7185e04468 piggyBac transposase 1 -- CG7185CC00645 P-element activity 0 Yes
Alleles Carried on Transgenic Constructs ( 4 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG7185 Class Mutagen Stocks Known lesion CG7185HMS00113 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG7185KK108487 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG7185GD14821 in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes CG7185NIG.7185R in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(3L)Exel6112 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD14821} NA P{KK108487} NA P{NIG.7185R} NA P{TRiP.HMS00113} NA
Insertions
	Type of insertions Name Expression data miscellaneous insertions P{PTT-GC}CG7185CC00645 NA P{RS3}CG7185CB-6365-3 NA P{wHy}CG7185DG14101 NA PBac{RB}CG7185e04468 NA
Gene Ontology: Function, Process & Cellular Component ( 7 unique terms )
Terms Based on Experimental Evidence ( 1 term )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
regulation of alternative mRNA splicing, via spliceosome inferred from mutant phenotype (Park et al., 2004)
Cellular Component ( 0 terms)
Terms Based on Predictions or Assertions ( 6 terms )
Molecular Function
CV term Evidence References
mRNA binding inferred from sequence or structural similarity (Lasko, 2000) nucleic acid binding inferred from electronic annotation with InterPro:IPR000504 (FlyBase Curators et al., 2004-) nucleotide binding inferred from electronic annotation with InterPro:IPR012677 (FlyBase Curators et al., 2004-)
Biological Process
CV term Evidence References
mRNA cleavage inferred from sequence or structural similarity with NCBI:NP_008938 (Mount and Salz, 2000)
Cellular Component
CV term Evidence References
mRNA cleavage factor complex inferred from sequence or structural similarity with NCBI:NP_008938 (Mount and Salz, 2000) nucleus inferred by curator from GO:0000381 (Park et al., 2004)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
protein-protein
Interacting group Assay References
CG7185 - AGO1 experimental knowledge based (Guruharsha et al., 2011) CG7185 - Bap60 experimental knowledge based (Guruharsha et al., 2011) CG7185 - CG10077 experimental knowledge based (Guruharsha et al., 2011) CG7185 - CG11060 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG7185 - CG11505 experimental knowledge based (Guruharsha et al., 2011) CG7185 - CG12493 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG7185 - CG13539 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG7185 - CG13567 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG7185 - CG14480 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG7185 - CG15625 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG7185 - CG17002 experimental knowledge based (Guruharsha et al., 2011) CG7185 - CG1889 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG7185 - CG2017 experimental knowledge based (Guruharsha et al., 2011) CG7185 - CG2199 experimental knowledge based (Guruharsha et al., 2011) CG7185 - CG3008 experimental knowledge based (Guruharsha et al., 2011) CG7185 - CG30491 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG7185 - CG32479 experimental knowledge based (Guruharsha et al., 2011) CG7185 - CG34159 experimental knowledge based (Guruharsha et al., 2011) CG7185 - CG3570 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG7185 - CG3689 experimental knowledge based (Guruharsha et al., 2011) CG7185 - CG5255 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG7185 - CG5623 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG7185 - CG7542 anti tag coimmunoprecipitation, peptide massfingerprinting, experimental knowledge based (Mintseris et al., 2009.11.23, Guruharsha et al., 2011) CG7185 - Cdk8 experimental knowledge based (Guruharsha et al., 2011) CG7185 - Der-2 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG7185 - MED10 experimental knowledge based (Guruharsha et al., 2011) CG7185 - MED11 experimental knowledge based (Guruharsha et al., 2011) CG7185 - MED14 experimental knowledge based (Guruharsha et al., 2011) CG7185 - MED15 experimental knowledge based (Guruharsha et al., 2011) CG7185 - MED16 experimental knowledge based (Guruharsha et al., 2011) CG7185 - MED17 experimental knowledge based (Guruharsha et al., 2011) CG7185 - MED18 experimental knowledge based (Guruharsha et al., 2011) CG7185 - MED20 experimental knowledge based (Guruharsha et al., 2011) CG7185 - MED23 experimental knowledge based (Guruharsha et al., 2011) CG7185 - MED24 experimental knowledge based (Guruharsha et al., 2011) CG7185 - MED25 experimental knowledge based (Guruharsha et al., 2011) CG7185 - MED27 experimental knowledge based (Guruharsha et al., 2011) CG7185 - MED30 experimental knowledge based (Guruharsha et al., 2011) CG7185 - MED4 experimental knowledge based (Guruharsha et al., 2011) CG7185 - MED6 experimental knowledge based (Guruharsha et al., 2011) CG7185 - MED7 experimental knowledge based (Guruharsha et al., 2011) CG7185 - MED8 experimental knowledge based (Guruharsha et al., 2011) CG7185 - Pa1 experimental knowledge based (Guruharsha et al., 2011) CG7185 - Psi experimental knowledge based (Guruharsha et al., 2011) CG7185 - Rrp45 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG7185 - Sec23 experimental knowledge based (Guruharsha et al., 2011) CG7185 - Snr1 experimental knowledge based (Guruharsha et al., 2011) CG7185 - ZAP3 experimental knowledge based (Guruharsha et al., 2011) CG7185 - alrm anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG7185 - boca experimental knowledge based (Guruharsha et al., 2011) CG7185 - brm experimental knowledge based (Guruharsha et al., 2011) CG7185 - bys anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG7185 - crn anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG7185 - dsh experimental knowledge based (Guruharsha et al., 2011) CG7185 - ebi experimental knowledge based (Guruharsha et al., 2011) CG7185 - enc experimental knowledge based (Guruharsha et al., 2011) CG7185 - fan anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG7185 - fh anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG7185 - ix experimental knowledge based (Guruharsha et al., 2011) CG7185 - mor experimental knowledge based (Guruharsha et al., 2011) CG7185 - osa experimental knowledge based (Guruharsha et al., 2011) CG7185 - ptip experimental knowledge based (Guruharsha et al., 2011) CG7185 - sec24 experimental knowledge based (Guruharsha et al., 2011) CG7185 - shrb anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG7185 - skd experimental knowledge based (Guruharsha et al., 2011)
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG7185 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 64355 DroID - A comprehensive database of gene and protein interactions. • FBgn0035872 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 38937
Orthologs
OrthoDB Orthologs (45) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6GJ08G Dipteran inclusive ortholog search EOG6N8RDR Insect inclusive ortholog search EOG6JHBBT Arthropod inclusive ortholog search EOG644J2C Metazoa inclusive ortholog search EOG66QKMX
Orthologs in Drosophila Species (EOG6GJ08G)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\CG7185     Drosophila simulans   Dsim\GD13000 Y   Drosophila sechellia   Dsec\GM24949 Y   Drosophila erecta   Dere\GG15090 Y   Drosophila yakuba   Dyak\GE21315 Y   Drosophila ananassae   Dana\GF23561 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA20165 Y   Drosophila persimilis   Dper\GL22549 Y   Drosophila willistoni   Dwil\GK16997 Y   Drosophila virilis   Dvir\GJ13124 Y   Drosophila mojavensis   Dmoj\GI12981 Y   Drosophila grimshawi   Dgri\GH15377 Y
Orthologs in non-Drosophila Dipterans (EOG6N8RDR)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL017164   Anopheles gambiae Malaria mosquito  Agam\AGAP005062   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ004892
Orthologs in non-Dipteran Insects (EOG6JHBBT)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\GB46014   Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG012132   Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH14718   Atta cephalotes Leafcutter ant  Acep\ACEP24143   Camponotus floridanus Florida carpenter ant  Cflo\CFLO13930   Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL18834   Linepithema humile Argentine ant  Lhum\LH18807   Pogonomyrmex barbatus Red harvester ant  Pbar\PB12605   Solenopsis invicta Red fire ant  Sinv\SINV17379   Acyrthosiphon pisum Pea aphid  Apim\ACYPI007967   Bombyx mori Silkmoth  Bmor\BGIBMGA009409   Pediculus humanus Human body louse  Phum\PHUM544500   Tribolium castaneum Red flour beetle  Tcas\GLEAN_08014
Orthologs in non-Insect Arthropods (EOG644J2C)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\JGI_V11_224649   Ixodes scapularis Deer tick  Isca\ISCW006578
Orthologs in non-Arthropod Metazoa (EOG66QKMX)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Caenorhabditis elegans Nematode  Cele\cfim-2   Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_015736gn   Danio rerio Zebrafish  Drer\cpsf6   Xenopus tropicalis Western clawed frog  Xtro\cpsf7   Xenopus tropicalis Western clawed frog  Xtro\cpsf6   Gallus gallus Domestic chicken  Ggal\CPSF6   Gallus gallus Domestic chicken  Ggal\ENSGALG00000013298   Mus musculus House mouse  Mmus\Cpsf6   Mus musculus House mouse  Mmus\Cpsf7   Rattus norvegicus Norway rat  Rnor\Lce1l   Rattus norvegicus Norway rat  Rnor\Cpsf7   Rattus norvegicus Norway rat  Rnor\Lce1f   Rattus norvegicus Norway rat  Rnor\Cpsf6   Homo sapiens Human  Hsap\CPSF6   Homo sapiens Human  Hsap\ENSG00000149532
Human Orthologs (2)
Gene OMIM HGNC Hsap\CPSF6     Hsap\ENSG00000149532
AAA Orthologs (11) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD13000 Drosophila sechellia Dsec\GM24949 Drosophila erecta Dere\GG15090 Drosophila yakuba Dyak\GE21315 Drosophila ananassae Dana\GF23561 Drosophila pseudoobscura pseudoobscura Dpse\GA20165 Drosophila persimilis Dper\GL22549 Drosophila willistoni Dwil\GK16997 Drosophila virilis Dvir\GJ13124 Drosophila mojavensis Dmoj\GI12981 Drosophila grimshawi Dgri\GH15377
Stocks & Reagents
Stocks Listed in FlyBase ( 5 )
Bloomington	20399 y1 w67c23; P{wHy}CG7185DG14101 34804 y1 sc* v1; P{TRiP.HMS00113}attP2
Harvard	- PBac{RB}CG7185e04468
Kyoto	124072 w1118; P{RS3}CG7185CB-6365-3
VDRC	v107147 P{KK108487}VIE-260B
Genomic Clones ( 1 )
	BACR13E21 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 211 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	LD25239
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT04369 LD06978 LD10473 LD12387 LD12962 LD12989 LD19192 LD22382 LD22675 LD24517 LD25908 LD26502 LD26907 LD27139 LD29415 LD30057 LD30619 LD30986 LD34023 LD35119 LD38164 LD47251 LP01129 LP01290 LP12726 LP14704 LP17109 LP22456 RE03820 RE10084 RE10120 RE11862 RE13746 RE16129 RE17332 RE23775 RE24153 RE29312 RE29324 RE29460 RE29553 RE32272 RE36232 RE44138 RE45855 RE48428 RE48669 RE51284 RE51469 RE53391 RE54913 RE58453 RE60118 RE60353 RE69864 RE69984 RE70193 RE72511 RE72833 RE73331 RE73536 RH17155 RH18801 RH18863 RH29053 RH33830 SD01375 SD01518 SD01904 SD02848 SD10548 SD12722 SD23657
Other clones	583 7995 16450 39429 46241 70546 192556 214287.72 522333 CK01.62D.G12 CK01.85D.E1 CK01.95A.C12 Dmel_neb_014901_0581_1231 EK050560 EK106027 EK122019 EK136208 EK152628 EK164952 EK197647 EK291234 EK291627 EK292302 EK295328 EN01836 EP08746 LD25230 RP003010308 RP003030785 RP003033501 RP003035180 RP003040364 RP003041223 RP003044923 RP003053673 RP003061081 RP003069038 RP003072745 RP003100159 RP003104451 RP003109716 RP003110110 RP003111551 RP003111576 RP003118374 RP003118829 RP003124407 RP003141234 RP003143383 RP003148260 RP003149571 RP003157498 RP003158368 RP003166956 RP003171188 RP003173242 RP003178441 RP003184339 RP003185421 RP003197875 RP003200726 RP003200955 RP003202346 RP003211265 RP003215175 RP003218299 RP003222488 RP003227036 RP003228039 RP003240315 RP003243698 RP003253472 RP003255814 RP003257012 RP003257294 RP003262537 RP003272538 RP003273679 RP003275207 RP003286779 RP003293542 RP003297625 RP003302109 RP003311243 RP003315885 RP003322642 RP003325162 RP003325198 RP003327334 RP003328562 RP003341321 RP003343814 RP003351324 RP003352214 RP003365346 RP003371519 RP003375411 RP003410870 RP003417737 RP003424659 RP003432347 RP003433291 RP003443274 RP003456873 RP003459105 RP003481373 RP003489084 RP003492813 RP003494782 RP003495640 RP003514947 RP003520373 RP003520457 RP003522936 RP003524512 RP003529522 RP003530283 RP003549388 RP003552620 RP003554044 RP003556765 RP003561091 RP003561882 RP003574338 RP003591534 RP003596185 RP003615743 RP003629053 RP003633845 RP003640712 RP003647676 RP003655708 RP003660438 RP003671324 RP003678070 RP003679646 RP003681314
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0035872 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 38937
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_139949 NM_001259736 RefSeq (Proteins) • NP_648206 NP_001246665 DDBJ / EMBL / GenBank • AA941220 AAF50445 AAL13792 AFH04336 AW942723 AY058563 CZ482226 CZ482227 Entrez Gene - A searchable database of RefSeq genes. • 38937 UniProtKB/Swiss-Prot • Q9VSH4
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • RNA recognition motif domain (IPR000504) Nucleotide-binding, alpha-beta plait (IPR012677) BDGP expression data - Patterns of gene expression in Drosophila embryogenesis • LD25239
Linkouts
	BioGRID - A database of protein and genetic interactions • 64355 DroID - A comprehensive database of gene and protein interactions. • FBgn0035872 DRSC - Results from RNAi screens. • FBgn0035872 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0035872 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG7185-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0035872 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 38937 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 38937 modMine - Data generated by the modENCODE project. • FBgn0035872
Synonyms & Secondary IDs ( 3 )
Reported As
Symbol Synonym	CFlm-68k (Park et al., 2004) cg7185 (Lasko, 2000) CG7185 (Stuart et al., 2007, Buszczak et al., 2007, Zhou et al., 2008, Keleman et al., 2009.8.5, Gandhi et al., 2007, Philipps et al., 2004, Kim et al., 2005, McIntyre et al., 2006, Ni et al., 2011.7.19, Japanese National Institute of Genetics, 2012.5.21)
Name Synonym
Secondary FlyBase IDs
References ( 34 )
Generate a list of	All references relating to this gene ( 34 )
List References by type	Research paper  ( 11 ) Supplementary material  ( 6 ) Personal communication to FlyBase  ( 10 ) FlyBase analysis  ( 2 ) Stock list  ( 1 ) Website  ( 1 ) Curated genome annotation  ( 2 )
Recent research papers ( 1 )
	Fisher et al., 2012, BMC Genomics 13: 506 Advances in genome-wide RNAi cellular screens: a case study using the Drosophila JAK/STAT pathway. [FBrf0220361] Show all research papers ...