FlyBase Gene Report: Dmel\GstO1

General Information

Symbol

Dmel\GstO1

Species

D. melanogaster

Name

Glutathione S transferase O1

Annotation Symbol

CG6662

Feature Type

protein_coding_gene

FlyBase ID

FBgn0035907

Gene Model Status

Current

Stock Availability

5 publicly available

Gene Snapshot

Glutathione S transferase O1 (GstO1) encodes a transferase involved in glutathione metabolism. [Date last reviewed: 2019-09-19]

Other Summaries

Alliance
Auto summary
Gene Group
Interactive Fly

Key Links

Genomic Location

Cytogenetic map

66D5-66D5

Sequence location

3L:8,523,742..8,524,866 [-]

Recombination map

3-26

RefSeq locus

NT_037436 REGION:8523742..8524866

Sequence

Get Decorated FASTA

Genomic Maps

JBrowse GBrowse

Help me choose

Other Genome Views

The following external sites may use different assemblies or annotations than FlyBase.

Function

GO Summary Ribbons

Gene Ontology (GO) Annotations (7 terms)

Molecular Function (4 terms)

Terms Based on Experimental Evidence (4 terms)

CV Term

Evidence

References

glutathione dehydrogenase (ascorbate) activity

inferred from direct assay

(Kim et al., 2006)

glutathione transferase activity

inferred from direct assay

(Saisawang et al., 2012)

NOT pyrimidodiazepine synthase activity

inferred from direct assay

(Kim et al., 2006)

transferase activity, transferring sulfur-containing groups

inferred from direct assay

(Kim et al., 2006)

Terms Based on Predictions or Assertions (1 term)

CV Term

Evidence

References

glutathione dehydrogenase (ascorbate) activity

inferred from biological aspect of ancestor with PANTHER:PTN000883725

(assigned by GO_Central )

(Gaudet et al., 2011)

Biological Process (2 terms)

Terms Based on Experimental Evidence (1 term)

CV Term

Evidence

References

glutathione metabolic process

inferred from direct assay

(Saisawang et al., 2012)

Terms Based on Predictions or Assertions (1 term)

CV Term

Evidence

References

oxidation-reduction process

inferred from biological aspect of ancestor with PANTHER:PTN000883725

(assigned by GO_Central )

(Gaudet et al., 2011)

Cellular Component (1 term)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (1 term)

CV Term

Evidence

References

cytoplasm

inferred from sequence or structural similarity with RGD:70952

(FlyBase Curators, 2008--)

Gene Group (FlyBase)

CYTOSOLIC GLUTATHIONE S-TRANSFERASES

DISULFIDE OXIDOREDUCTASES

OTHER SULFUR-CONTAINING GROUP TRANSFERASES

Protein Family (UniProt)

Protein Signatures (InterPro)

Summaries

Gene Group (FlyBase)

CYTOSOLIC GLUTATHIONE S-TRANSFERASES -: Glutathione transferases (glutathione S-transferases, GST) catalyze nucleophilic attack by reduced glutathione on nonpolar compounds that contain an electrophilic carbon, nitrogen, or sulfur atom. At least 14 classes of cytosolic GSTs have been identified in prokaryotes and eukaryotes: Theta, Omega, Sigma and Zeta exist in all eukaryotes. D. melanogaster has two additional classes, Delta and Epsilon. In D. mel, the class is indicated by the letter after the Gst prefix. (Adapted from FBrf0217315 and PMID:15822171).
DISULFIDE OXIDOREDUCTASES -: Disulfide oxidoreductases include dehydrogenases that catalyze the oxidation of substrate with reduced sulfide groups into substrate with oxidized disulfide bonds.
OTHER SULFUR-CONTAINING GROUP TRANSFERASES -: The Other sulfur-containing group transferases is a collection of transferases that do not fit into any of the other major transferases transferring sulfur-containing groups.

Gene Model and Products

Number of Transcripts

Number of Unique Polypeptides

Please see the JBrowse view of Dmel\GstO1 for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)

Isoform displayed:

Pfam protein domains

InterPro name

classification

start

end

Protein Domains (via SMART)

Isoform displayed:

SMART protein domains

InterPro name

classification

start

end

Comments on Gene Model

Gene model reviewed during 5.44

Low-frequency RNA-Seq exon junction(s) not annotated.

Sequence Ontology: Class of Gene

nuclear_gene

protein_coding_gene

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Assoc. CDS (aa)

GstO1-RA

FBtr0076652

NM_139980

954

254

Additional Transcript Data and Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

RefSeq ID

GenBank

GstO1-PA

FBpp0076376

30.0

254

7.53

NP_648237

AAF50402

Polypeptides with Identical Sequences

There is only one protein coding transcript and one polypeptide associated with this gene

Additional Polypeptide Data and Comments

Reported size (kDa)

Comments

External Data

Crossreferences

InterPro - A database of protein families, domains and functional sites

Linkouts

Sequences Consistent with the Gene Model

Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\GstO1 using the Feature Mapper tool.

External Data

Crossreferences

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

GstO1_1

Linkouts

Expression Data

Expression Summary Ribbons

Colored tiles in ribbon indicate that expression data has been curated by FlyBase for that anatomical location. Colorless tiles indicate that there is no curated data for that location.

For complete stage-specific expression data, view the modENCODE Development RNA-Seq section under High-Throughput Expression below.

Transcript Expression

in situ

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 1 -- 3

organism

Comment: maternally deposited

(Fisher et al., 2012)

embryonic stage 4 -- 6

organism

(Fisher et al., 2012)

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Evidence

References

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

GBrowse - Visual display of RNA-Seq signals

View Dmel\GstO1 in GBrowse 2

RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region

View exonic expression by developmental stage for Dmel\GstO1

View exonic expression by tissue for Dmel\GstO1

Bulk Downloads

RNA-Seq RPKM values for all genes

Reference

See Gelbart and Emmert, 2013 for analysis details and data files for all genes.

Developmental Proteome: Life Cycle

Developmental Proteome: Embryogenesis

External Data and Images

Linkouts

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0035907

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

FBgn0035907

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

CG6662-RA

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG6662

Flygut - An atlas of the Drosophila adult midgut

FBgn0035907

Images

FlyBase Wiki

Image Based Resources

Alleles, Insertions, and Transgenic Constructs

Classical and Insertion Alleles ( 1 )

For All Classical and Insertion Alleles Show

Other relevant insertions

Transgenic Constructs ( 5 )

For All Alleles Carried on Transgenic Constructs Show

Transgenic constructs containing/affecting coding region of GstO1

Transgenic constructs containing regulatory region of GstO1

Deletions and Duplications ( 0 )

Phenotypes

For more details about a specific phenotype click on the relevant allele symbol.

Lethality

Allele

viable

GstO1^LL04542

viable, with Dcr-2^UAS.cDa, Scer\GAL4^elav.PLu

GstO1^GD11995

viable, with Scer\GAL4^Mef2.PR

GstO1^GD11995

viable, with Scer\GAL4^pnr-MD237

GstO1^GD11995

viable, with Scer\GAL4^tin.CΔ4

GstO1^GD11995

Sterility

Allele

fertile

GstO1^LL04542

Other Phenotypes

Allele

chemical resistant, with Scer\GAL4^da.PU

GstO1^UAS.cKa

chemical sensitive

GstO1^LL04542

chemical sensitive, with Scer\GAL4^da.PU

GstO1^GD11995

chemical sensitive, with Scer\GAL4^Ddc.PU

GstO1^GD11995

chemical sensitive, with Scer\GAL4^elav.PU

GstO1^GD11995

chemical sensitive, with Scer\GAL4^ple.PU

GstO1^GD11995

Phenotype manifest in

Allele

Orthologs

Downloads

Download All DIOPT Orthologs

Download All OrthoDB Orthologs

Human Orthologs (via DIOPT v8.0)

Homo sapiens (Human) (5)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Hsap\GSTO1

13 of 15

Yes

11 of 15

1 of 15

1 of 15

1 of 15

Model Organism Orthologs (via DIOPT v8.0)

Mus musculus (laboratory mouse) (6)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Mmus\Gsto1

13 of 15

Yes

Mmus\Gsto2

10 of 15

Yes

1 of 15

1 of 15

1 of 15

1 of 15

Rattus norvegicus (Norway rat) (9)

Rnor\Gsto1

11 of 13

Yes

8 of 13

5 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Xenopus tropicalis (Western clawed frog) (4)

Xtro\gsto1

11 of 12

Yes

Xtro\gsto2

8 of 12

Yes

Xtro\LOC100498493

5 of 12

Yes

Xtro\LOC100498331

2 of 12

Yes

Danio rerio (Zebrafish) (2)

Drer\gsto1

9 of 15

Yes

Drer\gsto2

9 of 15

Yes

Caenorhabditis elegans (Nematode, roundworm) (5)

Cele\gsto-3

13 of 15

Yes

12 of 15

12 of 15

9 of 15

9 of 15

Arabidopsis thaliana (thale-cress) (36)

Atha\ERD9

5 of 9

Yes

Atha\GSTU15

5 of 9

Yes

Atha\GSTU16

5 of 9

Yes

Atha\GSTU18

5 of 9

Yes

Atha\GSTU19

5 of 9

Yes

Atha\GSTU22

5 of 9

Yes

Atha\GSTU23

5 of 9

Yes

Atha\GSTU24

5 of 9

Yes

Atha\GSTU25

5 of 9

Yes

Atha\GSTU26

5 of 9

Yes

Atha\GSTU27

5 of 9

Yes

Atha\GSTU1

4 of 9

Atha\GSTU3

4 of 9

Yes

Atha\GSTU4

4 of 9

Yes

Atha\GSTU5

4 of 9

Atha\GSTU6

4 of 9

Atha\GSTU7

4 of 9

Yes

Atha\GSTU8

4 of 9

Yes

Atha\GSTU9

4 of 9

Yes

Atha\GSTU10

4 of 9

Yes

Atha\GSTU11

4 of 9

Yes

Atha\GSTU12

4 of 9

Yes

Atha\GSTU13

4 of 9

Yes

Atha\GSTU20

4 of 9

Yes

Atha\GSTU21

4 of 9

Yes

Atha\GSTU28

4 of 9

Yes

Atha\GSTL2

3 of 9

Atha\GSTU2

3 of 9

Atha\GSTU14

3 of 9

Yes

2 of 9

2 of 9

1 of 9

1 of 9

Yes

Atha\DHAR1

1 of 9

Atha\DHAR2

1 of 9

Atha\DHAR3

1 of 9

Saccharomyces cerevisiae (Brewer's yeast) (3)

Scer\CAM1

1 of 15

Yes

Scer\TEF4

1 of 15

Yes

Scer\YGR201C

1 of 15

Yes

Schizosaccharomyces pombe (Fission yeast) (0)

No records found.

Ortholog(s) in Drosophila Species (via OrthoDB v9.1) ( EOG09190ELW )

Organism

Common Name

Gene

AAA Syntenic Ortholog

Multiple Dmel Genes in this Orthologous Group

Drosophila simulans

Drosophila sechellia

Drosophila erecta

Drosophila yakuba

Drosophila ananassae

Drosophila pseudoobscura pseudoobscura

Dpse\GA19760

Drosophila persimilis

Dper\GL15565

Drosophila willistoni

Dwil\GK20538

Orthologs in non-Drosophila Dipterans (via OrthoDB v9.1) ( EOG0915094O )

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Musca domestica

House fly

Mdoa\17021142

Glossina morsitans

Tsetse fly

Gmor\GMOY004675

Aedes aegypti

Yellow fever mosquito

Aaeg\GSTO1

Anopheles darlingi

American malaria mosquito

Adar\ADAC007726

Culex quinquefasciatus

Southern house mosquito

Cqui\CPIJ000031

Orthologs in non-Dipteran Insects (via OrthoDB v9.1) ( EOG090W0CH2 )

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Bombyx mori

Silkmoth

Bmor\BGIBMGA011819

Bombyx mori

Silkmoth

Bmor\Bmo.10572

Bombyx mori

Silkmoth

Bmor\gsto

Danaus plexippus

Monarch butterfly

Dple\DPOGS213590-PA

Danaus plexippus

Monarch butterfly

Dple\DPOGS213591-PA

Heliconius melpomene

Postman butterfly

Hmel\HMEL002742

Heliconius melpomene

Postman butterfly

Hmel\HMEL005474

Apis florea

Little honeybee

Aflo\2541839508

Apis mellifera

Western honey bee

Amel\GstO1

Bombus impatiens

Common eastern bumble bee

Bimp\BIMP23163

Bombus terrestris

Buff-tailed bumblebee

Bter\15209417

Linepithema humile

Argentine ant

Lhum\LH22186

Megachile rotundata

Alfalfa leafcutting bee

Mrot\MROTU:000dea

Nasonia vitripennis

Parasitic wasp

Nvit\Nasvi2EG004685

Dendroctonus ponderosae

Mountain pine beetle

Dpod\YQE_10416

Tribolium castaneum

Red flour beetle

Tcas\TC000055

Tribolium castaneum

Red flour beetle

Tcas\TC003873

Tribolium castaneum

Red flour beetle

Tcas\TC000054

Pediculus humanus

Human body louse

Phum\PHUM530530

Rhodnius prolixus

Kissing bug

Rpro\RPRC007741

Cimex lectularius

Bed bug

Clec\CLEC008904

Acyrthosiphon pisum

Pea aphid

Apim\ACYPI008340

Acyrthosiphon pisum

Pea aphid

Apim\ACYPI42456

Zootermopsis nevadensis

Nevada dampwood termite

Znev\Znev_00818

Zootermopsis nevadensis

Nevada dampwood termite

Znev\Znev_15795

Zootermopsis nevadensis

Nevada dampwood termite

Znev\Znev_00817

Orthologs in non-Insect Arthropods (via OrthoDB v9.1) ( EOG090X0CF0 )

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Strigamia maritima

European centipede

Smar\SMAR004928

Ixodes scapularis

Black-legged tick

Isca\ISCW003426

Ixodes scapularis

Black-legged tick

Isca\ISCW006479

Ixodes scapularis

Black-legged tick

Isca\ISCW006477

Ixodes scapularis

Black-legged tick

Isca\ISCW003939

Tetranychus urticae

Two-spotted spider mite

Turt\tetur01g02320

Tetranychus urticae

Two-spotted spider mite

Turt\tetur12g03900

Daphnia pulex

Water flea

Dpux\DAPPUDRAFT_318250

Orthologs in non-Arthropod Metazoa (via OrthoDB v9.1) ( EOG091G0IEA )

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Strongylocentrotus purpuratus

Purple sea urchin

Spur\Sp-Gsto1_2

Strongylocentrotus purpuratus

Purple sea urchin

Spur\Sp-Gsto1_1

Strongylocentrotus purpuratus

Purple sea urchin

Spur\Sp-Gsto1

Strongylocentrotus purpuratus

Purple sea urchin

Spur\SPU_003458gn

Ciona intestinalis

Vase tunicate

Cint\ENSCING00000011241

Ciona intestinalis

Vase tunicate

Cint\ENSCING00000005510

Ciona intestinalis

Vase tunicate

Cint\ENSCING00000017495

Ciona intestinalis

Vase tunicate

Cint\ENSCING00000005508

Ciona intestinalis

Vase tunicate

Cint\ENSCING00000008645

Gallus gallus

Domestic chicken

Ggal\GSTO1

Paralogs

Downloads

Download All DIOPT Paralogs

Paralogs (via DIOPT v8.0)

Drosophila melanogaster (Fruit fly) (34)

Gene Symbol

Score

Source

Alignment

9 of 10

7 of 10

2 of 10

2 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

Human Disease Associations

FlyBase Human Disease Model Reports

alcohol, response to, GSTO-related

Disease Model Summary Ribbon

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Allele

Disease

Evidence

References

Potential Models Based on Orthology ( 0 )

Human Ortholog

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 1 )

Allele

Disease

Interaction

References

GstO1^UAS.cKa

ameliorates Parkinson's disease

modeled by park¹

(Kim et al., 2012)

Disease Associations of Human Orthologs (via DIOPT v8.0 and OMIM)

Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.

Homo sapiens (Human)

Gene name

Score

OMIM

OMIM Phenotype

DO term

Complementation?

Transgene?

GSTO1; glutathione S-transferase omega 1

13 of 15

605482

GSTO2; glutathione S-transferase omega 2

11 of 15

612314

Functional Complementation Data

Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.

Interactions

Summary of Physical Interactions

esyN Network Diagram

Interactions Browser

View in Interactions Browser

Please see the Physical Interaction reports below for full details

protein-protein

Physical Interaction

Assay

References

GstO1 - GstO2

experimental knowledge based

(Guruharsha et al., 2011)

GstO1 - GstO3

experimental knowledge based

(Guruharsha et al., 2011)

Summary of Genetic Interactions

esyN Network Diagram

esyN Network Key:

Suppression

Enhancement

View in Interactions Browser

Please look at the allele data for full details of the genetic interactions

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

gfzf

suppressible

GstO1

(Smith et al., 2019)

External Data

Linkouts

BioGRID - A database of protein and genetic interactions.

64385

DroID - A comprehensive database of gene and protein interactions.

FBgn0035907

InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.

38975

MIST (protein-protein) - An integrated Molecular Interaction Database

GstO1

Pathways

Signaling Pathways (FlyBase)

Metabolic Pathways

FlyCyc Pathways - Pathways from a BioCyc PGDB for Dmel

glutathione-mediated detoxification I

KEGG Pathways - Wiring diagrams of molecular interactions, reactions and relations.

Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.

External Data

Linkouts

Genomic Location and Detailed Mapping Data

Chromosome (arm)

Recombination map

3-26

Cytogenetic map

66D5-66D5

Sequence location

3L:8,523,742..8,524,866 [-]

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

66D5-66D5

Limits computationally determined from genome sequence between P{PZ}Gug⁰³⁹²⁸&P{EP}CG6745^EP595b and P{lacW}foi^j8E8

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

3-26

(FlyBase, 2016)

3-20.1

(Comeron et al., 2012)

Left of (cM)

Right of (cM)

Notes

Stocks and Reagents

Stocks (5)

Bloomington

83804

y¹ sc^* v¹ sev²¹; P{TKO.GS04338}attP40

34727

y¹ sc^* v¹ sev²¹; P{TRiP.HMS01206}attP2

Kyoto

141285

y^* w^*; PBac{SAstopDsRed}LL04542 P{FRT(w^hs)}2A P{neoFRT}82B P{Car20y}96E/TM6B, Tb¹

VDRC

v26711

w¹¹¹⁸; P{GD11995}v26711

v26713

w¹¹¹⁸; P{GD11995}v26713/CyO

Genomic Clones (13)

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones (47)

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequenced

BDGP DGC clones

RE55814

Other clones

DPiM_RE55814

Drosophila Genomics Resource Center cDNA clones

For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

FBgn0035907

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

RNAi and Array Information

Linkouts

DRSC - Results frm RNAi screens

FBgn0035907

GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents

38975

Antibody Information

Laboratory Generated Antibodies

polyclonal

(Lee et al., 2015)

Commercially Available Antibodies

Other Information

Relationship to Other Genes

Source for database identify of

Source for identity of: GstO1 CG6662

(Saisawang et al., 2012)

Source for database merge of

Additional comments

FlyBase Curator comment: Note that (at least) three genes have been referred to as 'GstO1' (or a slight variant thereof) in the literature: CG6662 (in FBrf0217315), CG6673 (in FBrf0217543) and CG6781/se (in FBrf0191145). FlyBase has used 'GstO1' as the official symbol for CG6662 based on FBrf0217315 as this was the first peer-reviewed research paper to name the gene, and it presents a unified and systematic nomenclature for all Gst genes.

(FlyBase, 1992-)

Other Comments

Origin and Etymology

Discoverer

Etymology

Identification

External Crossreferences and Linkouts ( 42 )

Sequence Crossreferences

NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.

38975

GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.

GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.

RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.

UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information

Q9VSL6

Other crossreferences

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0035907

Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones

FBgn0035907

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

GstO1_1

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG6662

Flygut - An atlas of the Drosophila adult midgut

FBgn0035907

GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents

38975

iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)

InterPro - A database of protein families, domains and functional sites

KEGG Genes - Molecular building blocks of life in the genomic space.

Dmel_CG6662

modMine - A data warehouse for the modENCODE project

FBgn0035907

Linkouts

BioGRID - A database of protein and genetic interactions.

64385

DPiM - Drosophila Protein interaction map

FBgn0035907

DroID - A comprehensive database of gene and protein interactions.

FBgn0035907

DRSC - Results frm RNAi screens

FBgn0035907

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

FBgn0035907

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

CG6662-RA

FlyCyc Genes - Genes from a BioCyc PGDB for Dmel

FBGN0035907

FlyCyc Pathways - Pathways from a BioCyc PGDB for Dmel

glutathione-mediated detoxification I

FlyMine - An integrated database for Drosophila genomics

FBgn0035907

InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.

38975

KEGG Pathways - Wiring diagrams of molecular interactions, reactions and relations.

MIST (protein-protein) - An integrated Molecular Interaction Database

GstO1

Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.

Synonyms and Secondary IDs (6)

Reported As

Symbol Synonym

CG6662

(Hosono et al., 2015, Enya et al., 2014, Kim et al., 2012, Saisawang et al., 2012, Ni et al., 2010.12.1, Zhang et al., 2010, Walters et al., 2009, Li et al., 2008, Kim et al., 2007, Kim et al., 2006, Marco et al., 2004)

DmGSTO1

(Wongtrakul et al., 2014)

GSTO1

(Saisawang and Ketterman, 2014, Wongtrakul et al., 2014, Saisawang et al., 2012)

GstO1

(Choi et al., 2019, Nash et al., 2019, Williams-Simon et al., 2019, Hill et al., 2018, Transgenic RNAi Project members, 2017-, Bischof and FlyORF project members, 2014.6.20)

dGstO1

(Smith et al., 2019)

Name Synonyms

Glutathione S transferase O1

Secondary FlyBase IDs

Datasets (0)

Study focus (0)

Experimental Role

Project

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Title

References (42)

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