• Home
• Tools
  • Tools Overview
  • Query Tools

    
    • QuickSearch
    • QueryBuilder
    • TermLink
    • CytoSearch
    • RNA-Seq Search
    • Interactions Browser
    • ImageBrowse
    • Find A Person
    • Google™ FlyBase
  • Genomic/Map Tools

    
    • BLAST
    • GBrowse
    • GBrowse 2 Beta
    • CytoSearch
    • Feature Mapper
    • Aberrations Maps
    • Chromosome Maps
    • Coordinates Converter
  • Retrieve/Convert

    
    • Batch Download
    • Coordinates Converter
    • ID Converter
  • Data Submission

    
    • Fast-Track Your Paper
    • Submit Personal Comm
    • Add A New Person
    • Update Person Info
  • People

    
    • Find A Person
    • Add A New Person
    • Update Person Info
• Files
  • Files Overview
  • Current release
  • Archived releases
  • Map Conversion
  • FTP site:
  • Releases (FTP)
  • Genomes (FTP)
• Species
  • Phylogeny
  • Sequenced Species
  • Synteny Table
  • Color Illustrations
  • Abbreviations
• Documents
  • About FlyBase
  • Reference Manual:
  • Sections
  • Contents
  • Nomenclature
  • Release Notes
• Resources
  • All Resources
  • Model Organisms
  • Stock Collections
  • Vectors & Constructs
  • Other links:
  • BDGP
  • DGRC
  • DIS by issue
  • FlyExpress
  • Interactive Fly
  • modENCODE
  • Textpresso for Fly
• News
  • News
  • FlyBase Forum
  • FlyBase Positions
  • Meetings
  • Courses
  • Fly Board
  • White papers
  • Funding
  • bionet.dros
• Help
  • Google™ FlyBase
  • Site Map
  • FAQs
  • FlyBase Guides
  • Video Tutorials
  • Report help
  • New to Flies
  • Pers. comm.
  • Author guidelines
  • Contact FlyBase
• Archives
  • Prior Release
  • Other Archives
  • Coordinate Converter

Gene Dmel\GstO1

General Information
Symbol	Dmel\GstO1	Species	D. melanogaster
Name	Glutathione S transferase O1	Annotation symbol	CG6662
Feature type	protein_coding_gene	FlyBase ID	FBgn0035907
Gene Model Status	Current	Stock availability	3 publicly available
Genomic Location
Chromosome (arm)	3L	Recombination map
Cytogenetic map	66D5-66D5	Sequence location	3L:8,516,842..8,517,966 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene Glutathione S transferase O1 is referred to in FlyBase by the symbol Dmel\GstO1 (CG6662, FBgn0035907). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: glutathione dehydrogenase (ascorbate) activity; transferase activity, transferring sulfur-containing groups; glutathione transferase activity. There is experimental evidence that it is involved in the biological process: glutathione metabolic process. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Glutathione S-transferase, C-terminal; Glutathione S-transferase, C-terminal-like; Glutathione S-transferase, N-terminal; Glutathione S-transferase, omega-class; Glutathione S-transferase/chloride channel, C-terminal; Thioredoxin-like fold. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression. Peak expression observed within 00-06 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in stages of adults of both sexes. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult eye, adult hindgut, adult heart, adult fat body, adult ovary, adult testis, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1633106_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG6662. Gene sequence location is 3L:8516842..8517966.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 66D5-66D5   Limits computationally determined from genome sequence between P{PZ}Gug03928&P{EP}CG6745EP595b and P{lacW}foij8E8
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\GstO1 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.44
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) GstO1-RA FBtr0076652  NM_139980   954   254
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein GstO1-PA   FBpp0076376   30.0   254   7.53     NP_648237   AAF50402
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Glutathione S-transferase, N-terminal (IPR004045) Glutathione S-transferase, omega-class (IPR005442) Glutathione S-transferase, C-terminal-like (IPR010987) Thioredoxin-like fold (IPR012336) Glutathione S-transferase/chloride channel, C-terminal (IPR017933) Glutathione S-transferase, C-terminal (IPR004046)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE014296 AAF50402   AI062151   AI135874   AI259654   AI402136   AY071499 AAL49121   BI171834   BI369586   CO265415   CO331210   EC244635   EC250178   GH753538   GH773098   GH780290   GH783720   GH789299   GH789405   GH795440   GH807351   GH808433   GH827720   GH830740   GH831328   GH835695   GH839150   GH839370   GH845704   GH848433   GH848672   GH858054   GH858486   GH866204   GH866345   GH873042   GH875443   GH875567   GH877581   GH880246   GH881790   GH889521   GH894658   GH895427   GH904934   GH905212   GH906527   GH908539   GH915989   GH917863   GH926815   GH929943   GH930344   GH931096   GH937991   GH940661
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9VSL6
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
in situ Stage Tissue/Position (including subcellular localization) Reference embryonic stage 1 -- 3   organism   (Fisher et al., 2012) Comment:maternally deposited embryonic stage 4 -- 6   organism   (Fisher et al., 2012)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult eye, adult hindgut, adult heart, adult fat body, adult ovary, adult testis, larval/adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    60.6 Larval Midgut    21.1 Larval Hindgut    47.5 Larval Malpighian Tubules    21.2 Larval Fat Body    92.1 Larval Salivary Gland    8.8 Larval Trachea    75.65 Larval Carcass    289.45 Adult Head    97.9 Adult Eye    150.5 Adult Brain    35.2 Adult Thoracic-Abdominal Ganglion    87.3 Adult Crop    83.4 Adult Midgut    52.1 Adult Hindgut    132.3 Adult Malpighian Tubules    43.7 Adult Fat Body    123.1 Adult Salivary Gland    42.9 Adult Heart    117.45 Adult VirginFemale Spermatheca    65.8 Adult InseminatedFemale Spermatheca    82.9 Adult Ovary    333.4 Adult Testis    463.8 Adult Male Accessory Gland    95.7 Adult Carcass    107.3 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    60.6 Larval Midgut    21.1 Larval Hindgut    47.5 Larval Malpighian Tubules    21.2 Larval Fat Body    92.1 Larval Salivary Gland    8.8 Larval Trachea    75.65 Larval Carcass    289.45 Adult Head    97.9 Adult Eye    150.5 Adult Brain    35.2 Adult Thoracic-Abdominal Ganglion    87.3 Adult Crop    83.4 Adult Midgut    52.1 Adult Hindgut    132.3 Adult Malpighian Tubules    43.7 Adult Fat Body    123.1 Adult Salivary Gland    42.9 Adult Heart    117.45 Adult VirginFemale Spermatheca    65.8 Adult InseminatedFemale Spermatheca    82.9 Adult Ovary    333.4 Adult Testis    463.8 Adult Male Accessory Gland    95.7 Adult Carcass    107.3 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    60.6 Larval Midgut    21.1 Larval Hindgut    47.5 Larval Malpighian Tubules    21.2 Larval Fat Body    92.1 Larval Salivary Gland    8.8 Larval Trachea    75.65 Larval Carcass    289.45 Adult Head    97.9 Adult Eye    150.5 Adult Brain    35.2 Adult Thoracic-Abdominal Ganglion    87.3 Adult Crop    83.4 Adult Midgut    52.1 Adult Hindgut    132.3 Adult Malpighian Tubules    43.7 Adult Fat Body    123.1 Adult Salivary Gland    42.9 Adult Heart    117.45 Adult VirginFemale Spermatheca    65.8 Adult InseminatedFemale Spermatheca    82.9 Adult Ovary    333.4 Adult Testis    463.8 Adult Male Accessory Gland    95.7 Adult Carcass    107.3 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    60.6 Larval Midgut    21.1 Larval Hindgut    47.5 Larval Malpighian Tubules    21.2 Larval Fat Body    92.1 Larval Salivary Gland    8.8 Larval Trachea    75.65 Larval Carcass    289.45 Adult Head    97.9 Adult Eye    150.5 Adult Brain    35.2 Adult Thoracic-Abdominal Ganglion    87.3 Adult Crop    83.4 Adult Midgut    52.1 Adult Hindgut    132.3 Adult Malpighian Tubules    43.7 Adult Fat Body    123.1 Adult Salivary Gland    42.9 Adult Heart    117.45 Adult VirginFemale Spermatheca    65.8 Adult InseminatedFemale Spermatheca    82.9 Adult Ovary    333.4 Adult Testis    463.8 Adult Male Accessory Gland    95.7 Adult Carcass    107.3 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    60.6 Larval Midgut    21.1 Larval Hindgut    47.5 Larval Malpighian Tubules    21.2 Larval Fat Body    92.1 Larval Salivary Gland    8.8 Larval Trachea    75.65 Larval Carcass    289.45 Adult Head    97.9 Adult Eye    150.5 Adult Brain    35.2 Adult Thoracic-Abdominal Ganglion    87.3 Adult Crop    83.4 Adult Midgut    52.1 Adult Hindgut    132.3 Adult Malpighian Tubules    43.7 Adult Fat Body    123.1 Adult Salivary Gland    42.9 Adult Heart    117.45 Adult VirginFemale Spermatheca    65.8 Adult InseminatedFemale Spermatheca    82.9 Adult Ovary    333.4 Adult Testis    463.8 Adult Male Accessory Gland    95.7 Adult Carcass    107.3 Expression Level Scale  None   Low   Moderate   High  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    60.6 Larval Midgut    21.1 Larval Hindgut    47.5 Larval Malpighian Tubules    21.2 Larval Fat Body    92.1 Larval Salivary Gland    8.8 Larval Trachea    75.65 Larval Carcass    289.45 Adult Head    97.9 Adult Eye    150.5 Adult Brain    35.2 Adult Thoracic-Abdominal Ganglion    87.3 Adult Crop    83.4 Adult Midgut    52.1 Adult Hindgut    132.3 Adult Malpighian Tubules    43.7 Adult Fat Body    123.1 Adult Salivary Gland    42.9 Adult Heart    117.45 Adult VirginFemale Spermatheca    65.8 Adult InseminatedFemale Spermatheca    82.9 Adult Ovary    333.4 Adult Testis    463.8 Adult Male Accessory Gland    95.7 Adult Carcass    107.3 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    60.6 Larval Midgut    21.1 Larval Hindgut    47.5 Larval Malpighian Tubules    21.2 Larval Fat Body    92.1 Larval Salivary Gland    8.8 Larval Trachea    75.65 Larval Carcass    289.45 Adult Head    97.9 Adult Eye    150.5 Adult Brain    35.2 Adult Thoracic-Abdominal Ganglion    87.3 Adult Crop    83.4 Adult Midgut    52.1 Adult Hindgut    132.3 Adult Malpighian Tubules    43.7 Adult Fat Body    123.1 Adult Salivary Gland    42.9 Adult Heart    117.45 Adult VirginFemale Spermatheca    65.8 Adult InseminatedFemale Spermatheca    82.9 Adult Ovary    333.4 Adult Testis    463.8 Adult Male Accessory Gland    95.7 Adult Carcass    107.3 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    60.6 Larval Midgut    21.1 Larval Hindgut    47.5 Larval Malpighian Tubules    21.2 Larval Fat Body    92.1 Larval Salivary Gland    8.8 Larval Trachea    75.65 Larval Carcass    289.45 Adult Head    97.9 Adult Eye    150.5 Adult Brain    35.2 Adult Thoracic-Abdominal Ganglion    87.3 Adult Crop    83.4 Adult Midgut    52.1 Adult Hindgut    132.3 Adult Malpighian Tubules    43.7 Adult Fat Body    123.1 Adult Salivary Gland    42.9 Adult Heart    117.45 Adult VirginFemale Spermatheca    65.8 Adult InseminatedFemale Spermatheca    82.9 Adult Ovary    333.4 Adult Testis    463.8 Adult Male Accessory Gland    95.7 Adult Carcass    107.3 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    97.9   NA  Eye    150.5   NA  Brain    35.2   60.6  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    87.3   NA  Crop    83.4   21.1  Midgut    52.1   47.5  Hindgut    132.3   21.2  Malpighian Tubules    43.7   92.1  Fat Body    123.1   8.8  Salivary Gland    42.9   NA  Heart    117.45   75.65  Trachea    NA   NA  VirginFemale Spermatheca    65.8   NA  InseminatedFemale Spermatheca    82.9   NA  Ovary    333.4   NA  Testis    463.8   NA  Male Accessory Gland    95.7   289.45  Carcass    107.3 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    36 central nervous system, larvae L3    1 central nervous system, pupae P8    1 head, virgin 1-day female    1 head, virgin 4-day female    0 head, virgin 20-day female    2 head, mated 1-day female    1 head, mated 4-day female    1 head, mated 20-day female    1 head, mated 1-day male    1 head, mated 4-day male    0 head, mated 20-day male    3 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    1 digestive system, larvae L3 wandering    1 digestive system, 1-day adult    0 digestive system, 4-day adult    1 digestive system, 20-day adult    1 fat body, larvae L3 wandering    0 fat body, white prepupae    7 fat body, pupae P8    1 carcass, larvae L3 wandering    12 carcass, 1-day adult    1 carcass, 4-day adult    2 carcass, 20-day adult    2 ovary, virgin 4-day female    29 ovary, mated 4-day female    18 testis, mated 4-day male    62 accessory gland, mated 4-day male    4 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (36) central nervous system, larvae L3    1 central nervous system, pupae P8    1 head, virgin 1-day female    1 head, virgin 4-day female    0 head, virgin 20-day female    2 head, mated 1-day female    1 head, mated 4-day female    1 head, mated 20-day female    1 head, mated 1-day male    1 head, mated 4-day male    0 head, mated 20-day male    3 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    1 digestive system, larvae L3 wandering    1 digestive system, 1-day adult    0 digestive system, 4-day adult    1 digestive system, 20-day adult    1 fat body, larvae L3 wandering    0 fat body, white prepupae    7 fat body, pupae P8    1 carcass, larvae L3 wandering    12 carcass, 1-day adult    1 carcass, 4-day adult    2 carcass, 20-day adult    2 ovary, virgin 4-day female  (29) ovary, mated 4-day female    18 testis, mated 4-day male  (62) accessory gland, mated 4-day male    4 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    36 central nervous system, larvae L3    1 central nervous system, pupae P8    1 head, virgin 1-day female    1 head, virgin 4-day female    0 head, virgin 20-day female    2 head, mated 1-day female    1 head, mated 4-day female    1 head, mated 20-day female    1 head, mated 1-day male    1 head, mated 4-day male    0 head, mated 20-day male    3 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    1 digestive system, larvae L3 wandering    1 digestive system, 1-day adult    0 digestive system, 4-day adult    1 digestive system, 20-day adult    1 fat body, larvae L3 wandering    0 fat body, white prepupae    7 fat body, pupae P8    1 carcass, larvae L3 wandering    12 carcass, 1-day adult    1 carcass, 4-day adult    2 carcass, 20-day adult    2 ovary, virgin 4-day female    29 ovary, mated 4-day female    18 testis, mated 4-day male    62 accessory gland, mated 4-day male    4 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    36 central nervous system, larvae L3    1 central nervous system, pupae P8    1 head, virgin 1-day female    1 head, virgin 4-day female    0 head, virgin 20-day female    2 head, mated 1-day female    1 head, mated 4-day female    1 head, mated 20-day female    1 head, mated 1-day male    1 head, mated 4-day male    0 head, mated 20-day male    3 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    1 digestive system, larvae L3 wandering    1 digestive system, 1-day adult    0 digestive system, 4-day adult    1 digestive system, 20-day adult    1 fat body, larvae L3 wandering    0 fat body, white prepupae    7 fat body, pupae P8    1 carcass, larvae L3 wandering    12 carcass, 1-day adult    1 carcass, 4-day adult    2 carcass, 20-day adult    2 ovary, virgin 4-day female    29 ovary, mated 4-day female    18 testis, mated 4-day male    62 accessory gland, mated 4-day male    4 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    36 central nervous system, larvae L3    1 central nervous system, pupae P8    1 head, virgin 1-day female    1 head, virgin 4-day female    0 head, virgin 20-day female    2 head, mated 1-day female    1 head, mated 4-day female    1 head, mated 20-day female    1 head, mated 1-day male    1 head, mated 4-day male    0 head, mated 20-day male    3 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    1 digestive system, larvae L3 wandering    1 digestive system, 1-day adult    0 digestive system, 4-day adult    1 digestive system, 20-day adult    1 fat body, larvae L3 wandering    0 fat body, white prepupae    7 fat body, pupae P8    1 carcass, larvae L3 wandering    12 carcass, 1-day adult    1 carcass, 4-day adult    2 carcass, 20-day adult    2 ovary, virgin 4-day female    29 ovary, mated 4-day female    18 testis, mated 4-day male    62 accessory gland, mated 4-day male    4 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (36) central nervous system, larvae L3    1 central nervous system, pupae P8    1 head, virgin 1-day female    1 head, virgin 4-day female    0 head, virgin 20-day female    2 head, mated 1-day female    1 head, mated 4-day female    1 head, mated 20-day female    1 head, mated 1-day male    1 head, mated 4-day male    0 head, mated 20-day male    3 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    1 digestive system, larvae L3 wandering    1 digestive system, 1-day adult    0 digestive system, 4-day adult    1 digestive system, 20-day adult    1 fat body, larvae L3 wandering    0 fat body, white prepupae    7 fat body, pupae P8    1 carcass, larvae L3 wandering    12 carcass, 1-day adult    1 carcass, 4-day adult    2 carcass, 20-day adult    2 ovary, virgin 4-day female  29 ovary, mated 4-day female    18 testis, mated 4-day male  (62) accessory gland, mated 4-day male    4 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    36 central nervous system, larvae L3    1 central nervous system, pupae P8    1 head, virgin 1-day female    1 head, virgin 4-day female    0 head, virgin 20-day female    2 head, mated 1-day female    1 head, mated 4-day female    1 head, mated 20-day female    1 head, mated 1-day male    1 head, mated 4-day male    0 head, mated 20-day male    3 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    1 digestive system, larvae L3 wandering    1 digestive system, 1-day adult    0 digestive system, 4-day adult    1 digestive system, 20-day adult    1 fat body, larvae L3 wandering    0 fat body, white prepupae    7 fat body, pupae P8    1 carcass, larvae L3 wandering    12 carcass, 1-day adult    1 carcass, 4-day adult    2 carcass, 20-day adult    2 ovary, virgin 4-day female    29 ovary, mated 4-day female    18 testis, mated 4-day male    62 accessory gland, mated 4-day male    4 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    36 central nervous system, larvae L3    1 central nervous system, pupae P8    1 head, virgin 1-day female    1 head, virgin 4-day female    0 head, virgin 20-day female    2 head, mated 1-day female    1 head, mated 4-day female    1 head, mated 20-day female    1 head, mated 1-day male    1 head, mated 4-day male    0 head, mated 20-day male    3 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    1 digestive system, larvae L3 wandering    1 digestive system, 1-day adult    0 digestive system, 4-day adult    1 digestive system, 20-day adult    1 fat body, larvae L3 wandering    0 fat body, white prepupae    7 fat body, pupae P8    1 carcass, larvae L3 wandering    12 carcass, 1-day adult    1 carcass, 4-day adult    2 carcass, 20-day adult    2 ovary, virgin 4-day female    29 ovary, mated 4-day female    18 testis, mated 4-day male    62 accessory gland, mated 4-day male    4 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression. Peak expression observed within 00-06 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in stages of adults of both sexes. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    49 embryo 02-04hr    13 embryo 04-06hr    4 embryo 06-08hr    2 embryo 08-10hr    3 embryo 10-12hr    2 embryo 12-14hr    1 embryo 14-16hr    1 embryo 16-18hr    1 embryo 18-20hr    0 embryo 20-22hr    1 embryo 22-24hr    1 larva L1    1 larva L2    1 larva L3 12hr old    3 larva L3 puffstage 1-2    15 larva L3 puffstage 3-6    20 larva L3 puffstage 7-9    25 white prepupae new    18 white prepupae 12hr    27 white prepupae 24hr    25 pupae 2d postWPP    33 pupae 3d postWPP    18 pupae 4d postWPP    11 adult male 01day    18 adult male 05day    29 adult male 30day    22 adult female 01day    16 adult female 05day    40 adult female 30day    42 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (49) embryo 02-04hr    13 embryo 04-06hr    4 embryo 06-08hr    2 embryo 08-10hr    3 embryo 10-12hr    2 embryo 12-14hr    1 embryo 14-16hr    1 embryo 16-18hr    1 embryo 18-20hr    0 embryo 20-22hr    1 embryo 22-24hr    1 larva L1    1 larva L2    1 larva L3 12hr old    3 larva L3 puffstage 1-2    15 larva L3 puffstage 3-6    20 larva L3 puffstage 7-9    25 white prepupae new    18 white prepupae 12hr  (27) white prepupae 24hr    25 pupae 2d postWPP  (33) pupae 3d postWPP    18 pupae 4d postWPP    11 adult male 01day    18 adult male 05day  (29) adult male 30day    22 adult female 01day    16 adult female 05day  (40) adult female 30day  (42) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    49 embryo 02-04hr    13 embryo 04-06hr    4 embryo 06-08hr    2 embryo 08-10hr    3 embryo 10-12hr    2 embryo 12-14hr    1 embryo 14-16hr    1 embryo 16-18hr    1 embryo 18-20hr    0 embryo 20-22hr    1 embryo 22-24hr    1 larva L1    1 larva L2    1 larva L3 12hr old    3 larva L3 puffstage 1-2    15 larva L3 puffstage 3-6    20 larva L3 puffstage 7-9    25 white prepupae new    18 white prepupae 12hr    27 white prepupae 24hr    25 pupae 2d postWPP    33 pupae 3d postWPP    18 pupae 4d postWPP    11 adult male 01day    18 adult male 05day    29 adult male 30day    22 adult female 01day    16 adult female 05day    40 adult female 30day    42 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    49 embryo 02-04hr    13 embryo 04-06hr    4 embryo 06-08hr    2 embryo 08-10hr    3 embryo 10-12hr    2 embryo 12-14hr    1 embryo 14-16hr    1 embryo 16-18hr    1 embryo 18-20hr    0 embryo 20-22hr    1 embryo 22-24hr    1 larva L1    1 larva L2    1 larva L3 12hr old    3 larva L3 puffstage 1-2    15 larva L3 puffstage 3-6    20 larva L3 puffstage 7-9    25 white prepupae new    18 white prepupae 12hr    27 white prepupae 24hr    25 pupae 2d postWPP    33 pupae 3d postWPP    18 pupae 4d postWPP    11 adult male 01day    18 adult male 05day    29 adult male 30day    22 adult female 01day    16 adult female 05day    40 adult female 30day    42 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    49 embryo 02-04hr    13 embryo 04-06hr    4 embryo 06-08hr    2 embryo 08-10hr    3 embryo 10-12hr    2 embryo 12-14hr    1 embryo 14-16hr    1 embryo 16-18hr    1 embryo 18-20hr    0 embryo 20-22hr    1 embryo 22-24hr    1 larva L1    1 larva L2    1 larva L3 12hr old    3 larva L3 puffstage 1-2    15 larva L3 puffstage 3-6    20 larva L3 puffstage 7-9    25 white prepupae new    18 white prepupae 12hr    27 white prepupae 24hr    25 pupae 2d postWPP    33 pupae 3d postWPP    18 pupae 4d postWPP    11 adult male 01day    18 adult male 05day    29 adult male 30day    22 adult female 01day    16 adult female 05day    40 adult female 30day    42 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (49) embryo 02-04hr    13 embryo 04-06hr    4 embryo 06-08hr    2 embryo 08-10hr    3 embryo 10-12hr    2 embryo 12-14hr    1 embryo 14-16hr    1 embryo 16-18hr    1 embryo 18-20hr    0 embryo 20-22hr    1 embryo 22-24hr    1 larva L1    1 larva L2    1 larva L3 12hr old    3 larva L3 puffstage 1-2    15 larva L3 puffstage 3-6    20 larva L3 puffstage 7-9    25 white prepupae new    18 white prepupae 12hr  27 white prepupae 24hr    25 pupae 2d postWPP  (33) pupae 3d postWPP    18 pupae 4d postWPP    11 adult male 01day    18 adult male 05day  29 adult male 30day    22 adult female 01day    16 adult female 05day  (40) adult female 30day  (42) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    49 embryo 02-04hr    13 embryo 04-06hr    4 embryo 06-08hr    2 embryo 08-10hr    3 embryo 10-12hr    2 embryo 12-14hr    1 embryo 14-16hr    1 embryo 16-18hr    1 embryo 18-20hr    0 embryo 20-22hr    1 embryo 22-24hr    1 larva L1    1 larva L2    1 larva L3 12hr old    3 larva L3 puffstage 1-2    15 larva L3 puffstage 3-6    20 larva L3 puffstage 7-9    25 white prepupae new    18 white prepupae 12hr    27 white prepupae 24hr    25 pupae 2d postWPP    33 pupae 3d postWPP    18 pupae 4d postWPP    11 adult male 01day    18 adult male 05day    29 adult male 30day    22 adult female 01day    16 adult female 05day    40 adult female 30day    42 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    49 embryo 02-04hr    13 embryo 04-06hr    4 embryo 06-08hr    2 embryo 08-10hr    3 embryo 10-12hr    2 embryo 12-14hr    1 embryo 14-16hr    1 embryo 16-18hr    1 embryo 18-20hr    0 embryo 20-22hr    1 embryo 22-24hr    1 larva L1    1 larva L2    1 larva L3 12hr old    3 larva L3 puffstage 1-2    15 larva L3 puffstage 3-6    20 larva L3 puffstage 7-9    25 white prepupae new    18 white prepupae 12hr    27 white prepupae 24hr    25 pupae 2d postWPP    33 pupae 3d postWPP    18 pupae 4d postWPP    11 adult male 01day    18 adult male 05day    29 adult male 30day    22 adult female 01day    16 adult female 05day    40 adult female 30day    42 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    22 Schneider line 2 Sg4    4 embryonic 1182-4H    4 embryonic GM2    6 embryonic Kc167    13 embryonic S1    4 embryonic S3    15 leg disc CME L1    2 wing disc CME-W2    8 wing disc ML-DmD8    13 wing disc ML-DmD9    6 wing disc ML-DmD16-c3    5 wing disc ML-DmD21    7 wing disc ML-DmD32    5 haltere disc ML-DmD17-c3    12 eye-antennal disc ML-DmD11    11 antennal disc ML-DmD20-c5    16 mixed discs ML-DmD4-c1    4 CNS ML-DmBG1-c1    10 CNS ML-DmBG2-c2    11 tumorous blood cells mbn2    10 ovary fGS/OSS    3 ovary OSC    5 ovary OSS    1 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    22 Schneider line 2 Sg4    4 embryonic 1182-4H    4 embryonic GM2    6 embryonic Kc167    13 embryonic S1    4 embryonic S3    15 leg disc CME L1    2 wing disc CME-W2    8 wing disc ML-DmD8    13 wing disc ML-DmD9    6 wing disc ML-DmD16-c3    5 wing disc ML-DmD21    7 wing disc ML-DmD32    5 haltere disc ML-DmD17-c3    12 eye-antennal disc ML-DmD11    11 antennal disc ML-DmD20-c5    16 mixed discs ML-DmD4-c1    4 CNS ML-DmBG1-c1    10 CNS ML-DmBG2-c2    11 tumorous blood cells mbn2    10 ovary fGS/OSS    3 ovary OSC    5 ovary OSS    1 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    22 Schneider line 2 Sg4    4 embryonic 1182-4H    4 embryonic GM2    6 embryonic Kc167    13 embryonic S1    4 embryonic S3    15 leg disc CME L1    2 wing disc CME-W2    8 wing disc ML-DmD8    13 wing disc ML-DmD9    6 wing disc ML-DmD16-c3    5 wing disc ML-DmD21    7 wing disc ML-DmD32    5 haltere disc ML-DmD17-c3    12 eye-antennal disc ML-DmD11    11 antennal disc ML-DmD20-c5    16 mixed discs ML-DmD4-c1    4 CNS ML-DmBG1-c1    10 CNS ML-DmBG2-c2    11 tumorous blood cells mbn2    10 ovary fGS/OSS    3 ovary OSC    5 ovary OSS    1 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    22 Schneider line 2 Sg4    4 embryonic 1182-4H    4 embryonic GM2    6 embryonic Kc167    13 embryonic S1    4 embryonic S3    15 leg disc CME L1    2 wing disc CME-W2    8 wing disc ML-DmD8    13 wing disc ML-DmD9    6 wing disc ML-DmD16-c3    5 wing disc ML-DmD21    7 wing disc ML-DmD32    5 haltere disc ML-DmD17-c3    12 eye-antennal disc ML-DmD11    11 antennal disc ML-DmD20-c5    16 mixed discs ML-DmD4-c1    4 CNS ML-DmBG1-c1    10 CNS ML-DmBG2-c2    11 tumorous blood cells mbn2    10 ovary fGS/OSS    3 ovary OSC    5 ovary OSS    1 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    22 Schneider line 2 Sg4    4 embryonic 1182-4H    4 embryonic GM2    6 embryonic Kc167    13 embryonic S1    4 embryonic S3    15 leg disc CME L1    2 wing disc CME-W2    8 wing disc ML-DmD8    13 wing disc ML-DmD9    6 wing disc ML-DmD16-c3    5 wing disc ML-DmD21    7 wing disc ML-DmD32    5 haltere disc ML-DmD17-c3    12 eye-antennal disc ML-DmD11    11 antennal disc ML-DmD20-c5    16 mixed discs ML-DmD4-c1    4 CNS ML-DmBG1-c1    10 CNS ML-DmBG2-c2    11 tumorous blood cells mbn2    10 ovary fGS/OSS    3 ovary OSC    5 ovary OSS    1 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    22 Schneider line 2 Sg4    4 embryonic 1182-4H    4 embryonic GM2    6 embryonic Kc167    13 embryonic S1    4 embryonic S3    15 leg disc CME L1    2 wing disc CME-W2    8 wing disc ML-DmD8    13 wing disc ML-DmD9    6 wing disc ML-DmD16-c3    5 wing disc ML-DmD21    7 wing disc ML-DmD32    5 haltere disc ML-DmD17-c3    12 eye-antennal disc ML-DmD11    11 antennal disc ML-DmD20-c5    16 mixed discs ML-DmD4-c1    4 CNS ML-DmBG1-c1    10 CNS ML-DmBG2-c2    11 tumorous blood cells mbn2    10 ovary fGS/OSS    3 ovary OSC    5 ovary OSS    1 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    22 Schneider line 2 Sg4    4 embryonic 1182-4H    4 embryonic GM2    6 embryonic Kc167    13 embryonic S1    4 embryonic S3    15 leg disc CME L1    2 wing disc CME-W2    8 wing disc ML-DmD8    13 wing disc ML-DmD9    6 wing disc ML-DmD16-c3    5 wing disc ML-DmD21    7 wing disc ML-DmD32    5 haltere disc ML-DmD17-c3    12 eye-antennal disc ML-DmD11    11 antennal disc ML-DmD20-c5    16 mixed discs ML-DmD4-c1    4 CNS ML-DmBG1-c1    10 CNS ML-DmBG2-c2    11 tumorous blood cells mbn2    10 ovary fGS/OSS    3 ovary OSC    5 ovary OSS    1 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    22 Schneider line 2 Sg4    4 embryonic 1182-4H    4 embryonic GM2    6 embryonic Kc167    13 embryonic S1    4 embryonic S3    15 leg disc CME L1    2 wing disc CME-W2    8 wing disc ML-DmD8    13 wing disc ML-DmD9    6 wing disc ML-DmD16-c3    5 wing disc ML-DmD21    7 wing disc ML-DmD32    5 haltere disc ML-DmD17-c3    12 eye-antennal disc ML-DmD11    11 antennal disc ML-DmD20-c5    16 mixed discs ML-DmD4-c1    4 CNS ML-DmBG1-c1    10 CNS ML-DmBG2-c2    11 tumorous blood cells mbn2    10 ovary fGS/OSS    3 ovary OSC    5 ovary OSS    1 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    2 cold shock, 4-day adult    2 heat shock, 4-day adult    7 Cadmium 50 mM 6 hrs, larvae L3    5 Cadmium 50 mM 12 hrs, larvae L3    15 Cadmium 50 mM 48 hrs, 4-day adult    9 Cadmium 100 mM 48 hrs, 4-day adult    13 Copper 0.5 mM 12 hrs, larvae L3    0 Copper 15 mM 48 hrs, 4-day adult    8 Zinc 5 mM 12 hrs, larvae L3    2 Zinc 4.5 mM 48 hrs, 4-day adult    4 Ethanol 2.5% 3 hrs, larvae L3    17 Ethanol 5% 3 hrs, larvae L3    5 Ethanol 10% 3 hrs, larvae L3    5 Caffeine 1.5 mg/ml 4 hrs, larvae L3    5 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    18 Caffeine 25 mg/ml 48 hrs, 4-day adult    4 Paraquat 5 mM 48 hrs, 4-day adult    17 Paraquat 10 mM 48 hrs, 4-day adult    10 Rotenone 2 μg 12 hrs, larvae L3    6 Rotenone 8 μg 12 hrs, larvae L3    2 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    2 cold shock, 4-day adult    2 heat shock, 4-day adult    7 Cadmium 50 mM 6 hrs, larvae L3    5 Cadmium 50 mM 12 hrs, larvae L3    15 Cadmium 50 mM 48 hrs, 4-day adult    9 Cadmium 100 mM 48 hrs, 4-day adult    13 Copper 0.5 mM 12 hrs, larvae L3    0 Copper 15 mM 48 hrs, 4-day adult    8 Zinc 5 mM 12 hrs, larvae L3    2 Zinc 4.5 mM 48 hrs, 4-day adult    4 Ethanol 2.5% 3 hrs, larvae L3    17 Ethanol 5% 3 hrs, larvae L3    5 Ethanol 10% 3 hrs, larvae L3    5 Caffeine 1.5 mg/ml 4 hrs, larvae L3    5 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    18 Caffeine 25 mg/ml 48 hrs, 4-day adult    4 Paraquat 5 mM 48 hrs, 4-day adult    17 Paraquat 10 mM 48 hrs, 4-day adult    10 Rotenone 2 μg 12 hrs, larvae L3    6 Rotenone 8 μg 12 hrs, larvae L3    2 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    2 cold shock, 4-day adult    2 heat shock, 4-day adult    7 Cadmium 50 mM 6 hrs, larvae L3    5 Cadmium 50 mM 12 hrs, larvae L3    15 Cadmium 50 mM 48 hrs, 4-day adult    9 Cadmium 100 mM 48 hrs, 4-day adult    13 Copper 0.5 mM 12 hrs, larvae L3    0 Copper 15 mM 48 hrs, 4-day adult    8 Zinc 5 mM 12 hrs, larvae L3    2 Zinc 4.5 mM 48 hrs, 4-day adult    4 Ethanol 2.5% 3 hrs, larvae L3    17 Ethanol 5% 3 hrs, larvae L3    5 Ethanol 10% 3 hrs, larvae L3    5 Caffeine 1.5 mg/ml 4 hrs, larvae L3    5 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    18 Caffeine 25 mg/ml 48 hrs, 4-day adult    4 Paraquat 5 mM 48 hrs, 4-day adult    17 Paraquat 10 mM 48 hrs, 4-day adult    10 Rotenone 2 μg 12 hrs, larvae L3    6 Rotenone 8 μg 12 hrs, larvae L3    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    2 cold shock, 4-day adult    2 heat shock, 4-day adult    7 Cadmium 50 mM 6 hrs, larvae L3    5 Cadmium 50 mM 12 hrs, larvae L3    15 Cadmium 50 mM 48 hrs, 4-day adult    9 Cadmium 100 mM 48 hrs, 4-day adult    13 Copper 0.5 mM 12 hrs, larvae L3    0 Copper 15 mM 48 hrs, 4-day adult    8 Zinc 5 mM 12 hrs, larvae L3    2 Zinc 4.5 mM 48 hrs, 4-day adult    4 Ethanol 2.5% 3 hrs, larvae L3    17 Ethanol 5% 3 hrs, larvae L3    5 Ethanol 10% 3 hrs, larvae L3    5 Caffeine 1.5 mg/ml 4 hrs, larvae L3    5 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    18 Caffeine 25 mg/ml 48 hrs, 4-day adult    4 Paraquat 5 mM 48 hrs, 4-day adult    17 Paraquat 10 mM 48 hrs, 4-day adult    10 Rotenone 2 μg 12 hrs, larvae L3    6 Rotenone 8 μg 12 hrs, larvae L3    2 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    2 cold shock, 4-day adult    2 heat shock, 4-day adult    7 Cadmium 50 mM 6 hrs, larvae L3    5 Cadmium 50 mM 12 hrs, larvae L3    15 Cadmium 50 mM 48 hrs, 4-day adult    9 Cadmium 100 mM 48 hrs, 4-day adult    13 Copper 0.5 mM 12 hrs, larvae L3    0 Copper 15 mM 48 hrs, 4-day adult    8 Zinc 5 mM 12 hrs, larvae L3    2 Zinc 4.5 mM 48 hrs, 4-day adult    4 Ethanol 2.5% 3 hrs, larvae L3    17 Ethanol 5% 3 hrs, larvae L3    5 Ethanol 10% 3 hrs, larvae L3    5 Caffeine 1.5 mg/ml 4 hrs, larvae L3    5 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    18 Caffeine 25 mg/ml 48 hrs, 4-day adult    4 Paraquat 5 mM 48 hrs, 4-day adult    17 Paraquat 10 mM 48 hrs, 4-day adult    10 Rotenone 2 μg 12 hrs, larvae L3    6 Rotenone 8 μg 12 hrs, larvae L3    2 Expression Level Scale  Very low   Low   Moderate  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    2 cold shock, 4-day adult    2 heat shock, 4-day adult    7 Cadmium 50 mM 6 hrs, larvae L3    5 Cadmium 50 mM 12 hrs, larvae L3    15 Cadmium 50 mM 48 hrs, 4-day adult    9 Cadmium 100 mM 48 hrs, 4-day adult    13 Copper 0.5 mM 12 hrs, larvae L3    0 Copper 15 mM 48 hrs, 4-day adult    8 Zinc 5 mM 12 hrs, larvae L3    2 Zinc 4.5 mM 48 hrs, 4-day adult    4 Ethanol 2.5% 3 hrs, larvae L3    17 Ethanol 5% 3 hrs, larvae L3    5 Ethanol 10% 3 hrs, larvae L3    5 Caffeine 1.5 mg/ml 4 hrs, larvae L3    5 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    18 Caffeine 25 mg/ml 48 hrs, 4-day adult    4 Paraquat 5 mM 48 hrs, 4-day adult    17 Paraquat 10 mM 48 hrs, 4-day adult    10 Rotenone 2 μg 12 hrs, larvae L3    6 Rotenone 8 μg 12 hrs, larvae L3    2 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    2 cold shock, 4-day adult    2 heat shock, 4-day adult    7 Cadmium 50 mM 6 hrs, larvae L3    5 Cadmium 50 mM 12 hrs, larvae L3    15 Cadmium 50 mM 48 hrs, 4-day adult    9 Cadmium 100 mM 48 hrs, 4-day adult    13 Copper 0.5 mM 12 hrs, larvae L3    0 Copper 15 mM 48 hrs, 4-day adult    8 Zinc 5 mM 12 hrs, larvae L3    2 Zinc 4.5 mM 48 hrs, 4-day adult    4 Ethanol 2.5% 3 hrs, larvae L3    17 Ethanol 5% 3 hrs, larvae L3    5 Ethanol 10% 3 hrs, larvae L3    5 Caffeine 1.5 mg/ml 4 hrs, larvae L3    5 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    18 Caffeine 25 mg/ml 48 hrs, 4-day adult    4 Paraquat 5 mM 48 hrs, 4-day adult    17 Paraquat 10 mM 48 hrs, 4-day adult    10 Rotenone 2 μg 12 hrs, larvae L3    6 Rotenone 8 μg 12 hrs, larvae L3    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    2 cold shock, 4-day adult    2 heat shock, 4-day adult    7 Cadmium 50 mM 6 hrs, larvae L3    5 Cadmium 50 mM 12 hrs, larvae L3    15 Cadmium 50 mM 48 hrs, 4-day adult    9 Cadmium 100 mM 48 hrs, 4-day adult    13 Copper 0.5 mM 12 hrs, larvae L3    0 Copper 15 mM 48 hrs, 4-day adult    8 Zinc 5 mM 12 hrs, larvae L3    2 Zinc 4.5 mM 48 hrs, 4-day adult    4 Ethanol 2.5% 3 hrs, larvae L3    17 Ethanol 5% 3 hrs, larvae L3    5 Ethanol 10% 3 hrs, larvae L3    5 Caffeine 1.5 mg/ml 4 hrs, larvae L3    5 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    18 Caffeine 25 mg/ml 48 hrs, 4-day adult    4 Paraquat 5 mM 48 hrs, 4-day adult    17 Paraquat 10 mM 48 hrs, 4-day adult    10 Rotenone 2 μg 12 hrs, larvae L3    6 Rotenone 8 μg 12 hrs, larvae L3    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_02
External Data & Images
Linkouts	BDGP expression data • RE55814 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0035907 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG6662-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable, with Scer\GAL4pnr-MD237 GstO1GD11995 Phenotype manifest in Allele
Classical Alleles ( 0 )
For All Classical Alleles Show
Allele of GstO1 Class Mutagen Stocks Known lesion
Alleles Carried on Transgenic Constructs ( 3 )
For All Alleles Carried on Transgenic Constructs Show
Allele of GstO1 Class Mutagen Stocks Known lesion GstO1GD11995 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes GstO1HMS01206 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes GstO1Scer\UAS.cKa in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{UAS-CG6673.A.C31A} NA P{UAS-CG6673.A} NA P{UAS-CG6673.B} NA
Insertions
	Type of insertions Name Expression data
Gene Ontology: Function, Process & Cellular Component ( 6 unique terms )
Terms Based on Experimental Evidence ( 5 terms )
Molecular Function
CV term Evidence References
glutathione dehydrogenase (ascorbate) activity inferred from direct assay (Kim et al., 2006) glutathione transferase activity inferred from direct assay (Saisawang et al., 2012) NOT pyrimidodiazepine synthase activity inferred from direct assay (Kim et al., 2006) transferase activity, transferring sulfur-containing groups inferred from direct assay (Kim et al., 2006)
Biological Process
CV term Evidence References
glutathione metabolic process inferred from direct assay (Saisawang et al., 2012)
Cellular Component ( 0 terms)
Terms Based on Predictions or Assertions ( 3 terms )
Molecular Function
CV term Evidence References
glutathione dehydrogenase (ascorbate) activity non-traceable author statement (Kim et al., 2007) glutathione transferase activity inferred from sequence or structural similarity with NCBI_gi:4758484 (FlyBase, 1992-) non-traceable author statement (Kim et al., 2007)
Biological Process ( 0 terms)
Cellular Component
CV term Evidence References
cytoplasm inferred from sequence or structural similarity with rat Gsto1 (Curators, 2008--)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
protein-protein
Interacting group Assay References
GstO1 - Atx2 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) GstO1 - B52 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) GstO1 - CG10077 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) GstO1 - CG11107 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) GstO1 - CG15735 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) GstO1 - CG17768 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) GstO1 - CG34159 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) GstO1 - CG3689 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) GstO1 - CG3817 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) GstO1 - CG4611 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) GstO1 - CG4612 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) GstO1 - CG5792 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) GstO1 - CG6701 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) GstO1 - CG7194 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) GstO1 - CG9281 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) GstO1 - CG9775 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) GstO1 - CkIIα anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) GstO1 - GstO2 experimental knowledge based, anti tag coimmunoprecipitation, peptide massfingerprinting (Guruharsha et al., 2011, Mintseris et al., 2009.11.23) GstO1 - GstO3 anti tag coimmunoprecipitation, peptide massfingerprinting, experimental knowledge based (Mintseris et al., 2009.11.23, Guruharsha et al., 2011) GstO1 - Jra anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) GstO1 - Jupiter anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) GstO1 - NHP2 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) GstO1 - Rab5 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) GstO1 - Rbp1-like anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) GstO1 - Rsf1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) GstO1 - Saf-B anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) GstO1 - SmD3 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) GstO1 - SmG anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) GstO1 - Syp anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) GstO1 - U2af38 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) GstO1 - Zn72D anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) GstO1 - mRpL3 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) GstO1 - mRpL42 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) GstO1 - mRpL43 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) GstO1 - mor anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) GstO1 - skpA anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) GstO1 - snf anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23)
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions GstO1 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 64385 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0035907 DroID - A comprehensive database of gene and protein interactions. • FBgn0035907 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 38975
Orthologs
OrthoDB Orthologs (50) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6GB7SC Dipteran inclusive ortholog search No orthologs identified Insect inclusive ortholog search EOG6M90NN Arthropod inclusive ortholog search EOG60GB72 Metazoa inclusive ortholog search EOG66DZXH
Orthologs in Drosophila Species (EOG6GB7SC)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\GstO1     Drosophila simulans   Dsim\GD12978 Y   Drosophila sechellia   Dsec\GM24930 Y   Drosophila erecta   Dere\GG15073 Y   Drosophila yakuba   Dyak\GE21296 Y   Drosophila ananassae   Dana\GF10159 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA19760 Y   Drosophila persimilis   Dper\GL15565 Y   Drosophila willistoni   Dwil\GK20538 Y
Orthologs in non-Drosophila Dipterans (None identified)
No non-Drosophilid orthologies identified
Orthologs in non-Dipteran Insects (EOG6M90NN)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\GstO1 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG004685 Y Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH17308 Y Atta cephalotes Leafcutter ant  Acep\ACEP13018 Y Camponotus floridanus Florida carpenter ant  Cflo\CFLO19744 Y Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL18781 Y Linepithema humile Argentine ant  Lhum\LH22186 Y Pogonomyrmex barbatus Red harvester ant  Pbar\PB15656 Y Solenopsis invicta Red fire ant  Sinv\SINV16115 Y Acyrthosiphon pisum Pea aphid  Apim\ACYPI008340 Y Bombyx mori Silkmoth  Bmor\Bmo.10572 Y Bombyx mori Silkmoth  Bmor\BGIBMGA011819 Y Bombyx mori Silkmoth  Bmor\gsto Y Pediculus humanus Human body louse  Phum\PHUM530530 Y Tribolium castaneum Red flour beetle  Tcas\TC003873 Y
Orthologs in non-Insect Arthropods (EOG60GB72)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\JGI_V11_318250 Y Ixodes scapularis Deer tick  Isca\ISCW006477 Y Ixodes scapularis Deer tick  Isca\ISCW003939 Y Ixodes scapularis Deer tick  Isca\ISCW006479 Y Ixodes scapularis Deer tick  Isca\ISCW003426 Y
Orthologs in non-Arthropod Metazoa (EOG66DZXH)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Caenorhabditis elegans Nematode  Cele\gsto-3 Y Caenorhabditis elegans Nematode  Cele\gsto-2 Y Caenorhabditis elegans Nematode  Cele\C02D5.4 Y Caenorhabditis elegans Nematode  Cele\gsto-1 Y Caenorhabditis elegans Nematode  Cele\gst-44 Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_015497gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_019216gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_003458gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_028633gn Y Danio rerio Zebrafish  Drer\ENSDARG00000022183 Y Danio rerio Zebrafish  Drer\ENSDARG00000033285 Y Xenopus tropicalis Western clawed frog  Xtro\ENSXETG00000016907 Y Xenopus tropicalis Western clawed frog  Xtro\gsto1 Y Xenopus tropicalis Western clawed frog  Xtro\gsto2 Y Gallus gallus Domestic chicken  Ggal\GSTO1 Y Mus musculus House mouse  Mmus\Gsto1 Y Mus musculus House mouse  Mmus\Gsto2 Y Rattus norvegicus Norway rat  Rnor\Gsto1 Y Rattus norvegicus Norway rat  Rnor\Gsto2 Y Homo sapiens Human  Hsap\GSTO2 Y Homo sapiens Human  Hsap\GSTO1 Y
Human Orthologs (2)
Gene OMIM HGNC Hsap\GSTO2     Hsap\GSTO1
AAA Orthologs (8) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD12978 Drosophila sechellia Dsec\GM24930 Drosophila erecta Dere\GG15073 Drosophila yakuba Dyak\GE21296 Drosophila ananassae Dana\GF10159 Drosophila pseudoobscura pseudoobscura Dpse\GA19760 Drosophila persimilis Dper\GL15565 Drosophila willistoni Dwil\GK20538
Stocks & Reagents
Stocks Listed in FlyBase ( 3 )
Bloomington	34727 y1 sc* v1; P{TRiP.HMS01206}attP2
VDRC	v26711 w1118; P{GD11995}v26711 v26713 w1118; P{GD11995}v26713/CyO
Genomic Clones ( 2 )
	BACR06F06 BACR13D12 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 54 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	RE55814
Other clones	DPiM_RE55814
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	GH01247 GH13777 LP03121 RE13703
Other clones	31949 172886 EK142611 EK298828 GH08484 RP003044712 RP003085104 RP003090103 RP003096426 RP003106276 RP003112117 RP003120954 RP003138156 RP003138196 RP003169313 RP003200326 RP003219373 RP003246626 RP003261986 RP003274302 RP003300987 RP003323291 RP003331498 RP003333608 RP003352987 RP003358616 RP003371092 RP003382255 RP003396173 RP003403754 RP003440165 RP003443742 RP003454722 RP003458375 RP003462367 RP003468884 RP003474523 RP003498769 RP003506478 RP003561417 RP003563679 RP003579912 RP003607295 RP003627186 RP003642488 RP003655132 RP003656329 RP003680671
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0035907 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 38975
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of	Source for identity of: GstO1 CG6662 (Saisawang et al., 2012)
Source for database merge of
Additional comments	FlyBase Curator comment: Note that (at least) three genes have been referred to as 'GstO1' (or a slight variant thereof) in the literature: CG6662 (in FBrf0217315), CG6673 (in FBrf0217543) and CG6781/se (in FBrf0191145). FlyBase has used 'GstO1' as the official symbol for CG6662 based on FBrf0217315 as this was the first peer-reviewed research paper to name the gene, and it presents a unified and systematic nomenclature for all Gst genes. (FlyBase, 1992-)
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_139980 RefSeq (Proteins) • NP_648237 DDBJ / EMBL / GenBank • AAF50402 AAL49121 AY071499 BI369586 Entrez Gene - A searchable database of RefSeq genes. • 38975 UniProtKB/TrEMBL • Q9VSL6
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Glutathione S-transferase, N-terminal (IPR004045) Glutathione S-transferase, omega-class (IPR005442) Glutathione S-transferase, C-terminal-like (IPR010987) Thioredoxin-like fold (IPR012336) Glutathione S-transferase/chloride channel, C-terminal (IPR017933) Glutathione S-transferase, C-terminal (IPR004046) BDGP expression data - Patterns of gene expression in Drosophila embryogenesis • RE55814
Linkouts
	BioGRID - A database of protein and genetic interactions • 64385 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0035907 DroID - A comprehensive database of gene and protein interactions. • FBgn0035907 DRSC - Results from RNAi screens. • FBgn0035907 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0035907 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG6662-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0035907 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 38975 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 38975 modMine - Data generated by the modENCODE project. • FBgn0035907
Synonyms & Secondary IDs ( 4 )
Reported As
Symbol Synonym	CG6662 (Saisawang et al., 2012, Kim et al., 2007, Kim et al., 2006, Walters et al., 2009, Li et al., 2008, Kim et al., 2012, Marco et al., 2004, Ni et al., 2010.12.1) GstO1   GSTO1 (Saisawang et al., 2012)
Name Synonym	Glutathione S transferase O1
Secondary FlyBase IDs
References ( 21 )
Generate a list of	All references relating to this gene ( 21 )
List References by type	Research paper  ( 8 ) Supplementary material  ( 4 ) Personal communication to FlyBase  ( 5 ) Abstract  ( 1 ) FlyBase analysis  ( 2 ) Website  ( 1 )
Recent research papers ( 2 )
	Kim et al., 2012, J. Biol. Chem. 287(9): 6628--6641 Glutathione s-transferase omega 1 activity is sufficient to suppress neurodegeneration in a Drosophila model of Parkinson disease. [FBrf0217543] Saisawang et al., 2012, Biochem. J. 442(1): 181--190 A preliminary characterization of the cytosolic glutathione transferase proteome from Drosophila melanogaster. [FBrf0217315] Show all research papers ...