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Gene Dmel\CG5280

General Information
Symbol	Dmel\CG5280	Species	D. melanogaster
Name		Annotation symbol	CG5280
Feature type	protein_coding_gene	FlyBase ID	FBgn0035952
Gene Model Status	Current	Stock availability	3 publicly available
Genomic Location
Chromosome (arm)	3L	Recombination map
Cytogenetic map	66F1-66F1	Sequence location	3L:8,982,168..8,983,328 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG5280 (FBgn0035952). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Uncharacterised protein family UPF0193. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of extremely low expression. Peak expression observed in adult male stages. Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: adult testis. Comments on Affy2 ProbeSet: ProbeSet 1638851_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG5280. Gene sequence location is 3L:8982168..8983328.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2012_01	Sequence features BKN29124 HFA10498
FB2011_10
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 66F1-66F1   Limits computationally determined from genome sequence between P{PZ}l(3)0162901629&P{PZ}mRpL1210534 and P{EP}Hsp26EP3336&P{EP}Hsp26EP3315
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG5280 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG5280-RA FBtr0076552  NM_140021   987   250
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG5280-PA   FBpp0076279   28.6   250   10.23     NP_648278   AAF50335
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Uncharacterised protein family UPF0193 (IPR007914)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE014296 AAF50335   AI257987   AI946121   AY113308 AAM29313   BE978120   BE978341   BF486018   BF487348   BF490773   BF491873   BF501321   BF501537   CK657550   CO281865   CO283189   CO326037   EC062321   EC245677   EC251794   EC258435
UniProtKB/Swiss-Prot	Q9VSS7
UniProtKB/TrEMBL	Q8MZ83
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0035952    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0035952 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of extremely low expression. Peak expression observed in adult male stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0035952 expression level Developmental Stage   Expression Level embryo 00-02hr    7 embryo 02-04hr    13 embryo 04-06hr    37 embryo 06-08hr    33 embryo 08-10hr    45 embryo 10-12hr    67 embryo 12-14hr    78 embryo 14-16hr    73 embryo 16-18hr    97 embryo 18-20hr    72 embryo 20-22hr    38 embryo 22-24hr    46 larva L1    31 larva L2    26 larva L3 12hr old    21 larva L3 puffstage 1-2    356 larva L3 puffstage 3-6    856 larva L3 puffstage 7-9    928 white prepupae new    928 white prepupae 12hr    1645 white prepupae 24hr    2369 pupae 2d postWPP    2720 pupae 3d postWPP    2498 pupae 4d postWPP    2241 adult male 01day    3738 adult male 05day    5246 adult male 30day    4996 adult female 01day    33 adult female 05day    39 adult female 30day    22 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr    7 embryo 02-04hr    13 embryo 04-06hr    37 embryo 06-08hr    33 embryo 08-10hr    45 embryo 10-12hr    67 embryo 12-14hr    78 embryo 14-16hr    73 embryo 16-18hr    97 embryo 18-20hr    72 embryo 20-22hr    38 embryo 22-24hr    46 larva L1    31 larva L2    26 larva L3 12hr old    21 larva L3 puffstage 1-2  (356) larva L3 puffstage 3-6  (856) larva L3 puffstage 7-9  (928) white prepupae new  (928) white prepupae 12hr  (1645) white prepupae 24hr  (2369) pupae 2d postWPP  (2720) pupae 3d postWPP  (2498) pupae 4d postWPP  (2241) adult male 01day  (3738) adult male 05day  (5246) adult male 30day  (4996) adult female 01day    33 adult female 05day    39 adult female 30day    22 Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    7 embryo 02-04hr    13 embryo 04-06hr    37 embryo 06-08hr    33 embryo 08-10hr    45 embryo 10-12hr    67 embryo 12-14hr    78 embryo 14-16hr    73 embryo 16-18hr    97 embryo 18-20hr    72 embryo 20-22hr    38 embryo 22-24hr    46 larva L1    31 larva L2    26 larva L3 12hr old    21 larva L3 puffstage 1-2    356 larva L3 puffstage 3-6    856 larva L3 puffstage 7-9    928 white prepupae new    928 white prepupae 12hr  (1645) white prepupae 24hr  (2369) pupae 2d postWPP  (2720) pupae 3d postWPP  (2498) pupae 4d postWPP  (2241) adult male 01day  (3738) adult male 05day  (5246) adult male 30day  (4996) adult female 01day    33 adult female 05day    39 adult female 30day    22 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    7 embryo 02-04hr    13 embryo 04-06hr    37 embryo 06-08hr    33 embryo 08-10hr    45 embryo 10-12hr    67 embryo 12-14hr    78 embryo 14-16hr    73 embryo 16-18hr    97 embryo 18-20hr    72 embryo 20-22hr    38 embryo 22-24hr    46 larva L1    31 larva L2    26 larva L3 12hr old    21 larva L3 puffstage 1-2    356 larva L3 puffstage 3-6    856 larva L3 puffstage 7-9    928 white prepupae new    928 white prepupae 12hr    1645 white prepupae 24hr    2369 pupae 2d postWPP    2720 pupae 3d postWPP    2498 pupae 4d postWPP    2241 adult male 01day    3738 adult male 05day    5246 adult male 30day    4996 adult female 01day    33 adult female 05day    39 adult female 30day    22 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    7 embryo 02-04hr    13 embryo 04-06hr    37 embryo 06-08hr    33 embryo 08-10hr    45 embryo 10-12hr    67 embryo 12-14hr    78 embryo 14-16hr    73 embryo 16-18hr    97 embryo 18-20hr    72 embryo 20-22hr    38 embryo 22-24hr    46 larva L1    31 larva L2    26 larva L3 12hr old    21 larva L3 puffstage 1-2    356 larva L3 puffstage 3-6    856 larva L3 puffstage 7-9    928 white prepupae new    928 white prepupae 12hr    1645 white prepupae 24hr    2369 pupae 2d postWPP    2720 pupae 3d postWPP    2498 pupae 4d postWPP    2241 adult male 01day    3738 adult male 05day    5246 adult male 30day    4996 adult female 01day    33 adult female 05day    39 adult female 30day    22 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0035952 expression level Developmental Stage   Expression Level embryo 00-02hr    7 embryo 02-04hr    13 embryo 04-06hr    37 embryo 06-08hr    33 embryo 08-10hr    45 embryo 10-12hr    67 embryo 12-14hr    78 embryo 14-16hr    73 embryo 16-18hr    97 embryo 18-20hr    72 embryo 20-22hr    38 embryo 22-24hr    46 larva L1    31 larva L2    26 larva L3 12hr old    21 larva L3 puffstage 1-2    356 larva L3 puffstage 3-6    856 larva L3 puffstage 7-9    928 white prepupae new    928 white prepupae 12hr    1645 white prepupae 24hr    2369 pupae 2d postWPP    2720 pupae 3d postWPP    2498 pupae 4d postWPP    2241 adult male 01day    3738 adult male 05day    5246 adult male 30day    4996 adult female 01day    33 adult female 05day    39 adult female 30day    22 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr    7 embryo 02-04hr    13 embryo 04-06hr    37 embryo 06-08hr    33 embryo 08-10hr    45 embryo 10-12hr    67 embryo 12-14hr    78 embryo 14-16hr    73 embryo 16-18hr    97 embryo 18-20hr    72 embryo 20-22hr    38 embryo 22-24hr    46 larva L1    31 larva L2    26 larva L3 12hr old    21 larva L3 puffstage 1-2  (356) larva L3 puffstage 3-6  (856) larva L3 puffstage 7-9  (928) white prepupae new  (928) white prepupae 12hr  (1645) white prepupae 24hr  (2369) pupae 2d postWPP  (2720) pupae 3d postWPP  (2498) pupae 4d postWPP  (2241) adult male 01day  (3738) adult male 05day  (5246) adult male 30day  (4996) adult female 01day    33 adult female 05day    39 adult female 30day    22 Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    7 embryo 02-04hr    13 embryo 04-06hr    37 embryo 06-08hr    33 embryo 08-10hr    45 embryo 10-12hr    67 embryo 12-14hr    78 embryo 14-16hr    73 embryo 16-18hr    97 embryo 18-20hr    72 embryo 20-22hr    38 embryo 22-24hr    46 larva L1    31 larva L2    26 larva L3 12hr old    21 larva L3 puffstage 1-2    356 larva L3 puffstage 3-6    856 larva L3 puffstage 7-9    928 white prepupae new    928 white prepupae 12hr  1645 white prepupae 24hr  2369 pupae 2d postWPP  (2720) pupae 3d postWPP  (2498) pupae 4d postWPP  2241 adult male 01day  (3738) adult male 05day  (5246) adult male 30day  (4996) adult female 01day    33 adult female 05day    39 adult female 30day    22 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    7 embryo 02-04hr    13 embryo 04-06hr    37 embryo 06-08hr    33 embryo 08-10hr    45 embryo 10-12hr    67 embryo 12-14hr    78 embryo 14-16hr    73 embryo 16-18hr    97 embryo 18-20hr    72 embryo 20-22hr    38 embryo 22-24hr    46 larva L1    31 larva L2    26 larva L3 12hr old    21 larva L3 puffstage 1-2    356 larva L3 puffstage 3-6    856 larva L3 puffstage 7-9    928 white prepupae new    928 white prepupae 12hr    1645 white prepupae 24hr    2369 pupae 2d postWPP    2720 pupae 3d postWPP    2498 pupae 4d postWPP    2241 adult male 01day    3738 adult male 05day    5246 adult male 30day    4996 adult female 01day    33 adult female 05day    39 adult female 30day    22 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    7 embryo 02-04hr    13 embryo 04-06hr    37 embryo 06-08hr    33 embryo 08-10hr    45 embryo 10-12hr    67 embryo 12-14hr    78 embryo 14-16hr    73 embryo 16-18hr    97 embryo 18-20hr    72 embryo 20-22hr    38 embryo 22-24hr    46 larva L1    31 larva L2    26 larva L3 12hr old    21 larva L3 puffstage 1-2    356 larva L3 puffstage 3-6    856 larva L3 puffstage 7-9    928 white prepupae new    928 white prepupae 12hr    1645 white prepupae 24hr    2369 pupae 2d postWPP    2720 pupae 3d postWPP    2498 pupae 4d postWPP    2241 adult male 01day    3738 adult male 05day    5246 adult male 30day    4996 adult female 01day    33 adult female 05day    39 adult female 30day    22 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0035952    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0035952 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: adult testis. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0035952 expression level Tissue   Expression Level Larval Central Nervous System    2.3 Larval Midgut    6.2 Larval Hindgut    7.1 Larval Malpighian Tubules    4.2 Larval Fat Body no informative data Larval Salivary Gland    2.3 Larval Trachea    6.6 Larval Carcass    3.8 Adult Head no informative data Adult Eye    2.45 Adult Brain    1.6 Adult Thoracic-Abdominal Ganglion    5 Adult Crop    6.7 Adult Midgut    7.6 Adult Hindgut    5.9 Adult Malpighian Tubules    2.9 Adult Fat Body    3.5 Adult Salivary Gland no informative data Adult Heart    3.05 Adult VirginFemale Spermatheca    8.3 Adult InseminatedFemale Spermatheca    6.9 Adult Ovary    1.5 Adult Testis    649.6 Adult Male Accessory Gland    5.3 Adult Carcass    7.1 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    2.3 Larval Midgut    6.2 Larval Hindgut    7.1 Larval Malpighian Tubules    4.2 Larval Fat Body no informative data Larval Salivary Gland    2.3 Larval Trachea    6.6 Larval Carcass    3.8 Adult Head no informative data Adult Eye    2.45 Adult Brain    1.6 Adult Thoracic-Abdominal Ganglion    5 Adult Crop    6.7 Adult Midgut    7.6 Adult Hindgut    5.9 Adult Malpighian Tubules    2.9 Adult Fat Body    3.5 Adult Salivary Gland no informative data Adult Heart    3.05 Adult VirginFemale Spermatheca    8.3 Adult InseminatedFemale Spermatheca    6.9 Adult Ovary    1.5 Adult Testis  (649.6) Adult Male Accessory Gland    5.3 Adult Carcass    7.1 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    2.3 Larval Midgut    6.2 Larval Hindgut    7.1 Larval Malpighian Tubules    4.2 Larval Fat Body no informative data Larval Salivary Gland    2.3 Larval Trachea    6.6 Larval Carcass    3.8 Adult Head no informative data Adult Eye    2.45 Adult Brain    1.6 Adult Thoracic-Abdominal Ganglion    5 Adult Crop    6.7 Adult Midgut    7.6 Adult Hindgut    5.9 Adult Malpighian Tubules    2.9 Adult Fat Body    3.5 Adult Salivary Gland no informative data Adult Heart    3.05 Adult VirginFemale Spermatheca    8.3 Adult InseminatedFemale Spermatheca    6.9 Adult Ovary    1.5 Adult Testis    649.6 Adult Male Accessory Gland    5.3 Adult Carcass    7.1 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    2.3 Larval Midgut    6.2 Larval Hindgut    7.1 Larval Malpighian Tubules    4.2 Larval Fat Body no informative data Larval Salivary Gland    2.3 Larval Trachea    6.6 Larval Carcass    3.8 Adult Head no informative data Adult Eye    2.45 Adult Brain    1.6 Adult Thoracic-Abdominal Ganglion    5 Adult Crop    6.7 Adult Midgut    7.6 Adult Hindgut    5.9 Adult Malpighian Tubules    2.9 Adult Fat Body    3.5 Adult Salivary Gland no informative data Adult Heart    3.05 Adult VirginFemale Spermatheca    8.3 Adult InseminatedFemale Spermatheca    6.9 Adult Ovary    1.5 Adult Testis    649.6 Adult Male Accessory Gland    5.3 Adult Carcass    7.1 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0035952 expression level Tissue   Expression Level Larval Central Nervous System    2.3 Larval Midgut    6.2 Larval Hindgut    7.1 Larval Malpighian Tubules    4.2 Larval Fat Body no informative data Larval Salivary Gland    2.3 Larval Trachea    6.6 Larval Carcass    3.8 Adult Head no informative data Adult Eye    2.45 Adult Brain    1.6 Adult Thoracic-Abdominal Ganglion    5 Adult Crop    6.7 Adult Midgut    7.6 Adult Hindgut    5.9 Adult Malpighian Tubules    2.9 Adult Fat Body    3.5 Adult Salivary Gland no informative data Adult Heart    3.05 Adult VirginFemale Spermatheca    8.3 Adult InseminatedFemale Spermatheca    6.9 Adult Ovary    1.5 Adult Testis    649.6 Adult Male Accessory Gland    5.3 Adult Carcass    7.1 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    2.3 Larval Midgut    6.2 Larval Hindgut    7.1 Larval Malpighian Tubules    4.2 Larval Fat Body no informative data Larval Salivary Gland    2.3 Larval Trachea    6.6 Larval Carcass    3.8 Adult Head no informative data Adult Eye    2.45 Adult Brain    1.6 Adult Thoracic-Abdominal Ganglion    5 Adult Crop    6.7 Adult Midgut    7.6 Adult Hindgut    5.9 Adult Malpighian Tubules    2.9 Adult Fat Body    3.5 Adult Salivary Gland no informative data Adult Heart    3.05 Adult VirginFemale Spermatheca    8.3 Adult InseminatedFemale Spermatheca    6.9 Adult Ovary    1.5 Adult Testis  649.6 Adult Male Accessory Gland    5.3 Adult Carcass    7.1 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    2.3 Larval Midgut    6.2 Larval Hindgut    7.1 Larval Malpighian Tubules    4.2 Larval Fat Body no informative data Larval Salivary Gland    2.3 Larval Trachea    6.6 Larval Carcass    3.8 Adult Head no informative data Adult Eye    2.45 Adult Brain    1.6 Adult Thoracic-Abdominal Ganglion    5 Adult Crop    6.7 Adult Midgut    7.6 Adult Hindgut    5.9 Adult Malpighian Tubules    2.9 Adult Fat Body    3.5 Adult Salivary Gland no informative data Adult Heart    3.05 Adult VirginFemale Spermatheca    8.3 Adult InseminatedFemale Spermatheca    6.9 Adult Ovary    1.5 Adult Testis    649.6 Adult Male Accessory Gland    5.3 Adult Carcass    7.1 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    2.3 Larval Midgut    6.2 Larval Hindgut    7.1 Larval Malpighian Tubules    4.2 Larval Fat Body no informative data Larval Salivary Gland    2.3 Larval Trachea    6.6 Larval Carcass    3.8 Adult Head no informative data Adult Eye    2.45 Adult Brain    1.6 Adult Thoracic-Abdominal Ganglion    5 Adult Crop    6.7 Adult Midgut    7.6 Adult Hindgut    5.9 Adult Malpighian Tubules    2.9 Adult Fat Body    3.5 Adult Salivary Gland no informative data Adult Heart    3.05 Adult VirginFemale Spermatheca    8.3 Adult InseminatedFemale Spermatheca    6.9 Adult Ovary    1.5 Adult Testis    649.6 Adult Male Accessory Gland    5.3 Adult Carcass    7.1 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body no informative data Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head no informative data Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland no informative data Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    no informative data   NA  Eye    2.45   NA  Brain    1.6   2.3  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    5   NA  Crop    6.7   6.2  Midgut    7.6   7.1  Hindgut    5.9   4.2  Malpighian Tubules    2.9   no informative data  Fat Body    3.5   2.3  Salivary Gland    no informative data   NA  Heart    3.05   6.6  Trachea    NA   NA  VirginFemale Spermatheca    8.3   NA  InseminatedFemale Spermatheca    6.9   NA  Ovary    1.5   NA  Testis    649.6   NA  Male Accessory Gland    5.3   3.8  Carcass    7.1 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_28
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0035952 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG5280-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable, with Scer\GAL4pnr-MD237 CG5280GD11599 Phenotype manifest in Allele
Classical Alleles ( 0 )
For All Classical Alleles Show
Allele of CG5280 Class Mutagen Stocks Known lesion
Alleles Carried on Transgenic Constructs ( 2 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG5280 Class Mutagen Stocks Known lesion CG5280GD11599 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes CG5280KK109124 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes
Aneuploid Aberrations
Disrupted in	Df(3L)Exel6113 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD11599} NA P{KK109124} NA
Insertions
	Type of insertions Name Expression data
Gene Ontology: Function, Process & Cellular Component ( 0 unique terms )
	There is no information supporting a biological process, cellular component or molecular function term for this gene. (Based on a review of available data before: 2006)
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 0 terms )
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG5280 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 64437 DroID - A comprehensive database of gene and protein interactions. • FBgn0035952 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 39033
Orthologs
Genome-wide drosophilid orthologs	Dana\GF10134 Dere\GG15044 Dgri\GH14959 Dmoj\GI11485 Dper\GL15083 Dpse\GA18782 Dsec\GM24898 Dsim\GD12948 Dvir\GJ13680 Dwil\GK12283 Dyak\GE21268
Curated drosophilid orthologs	Dpse\GA18782
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL001156-PA Aedes aegypti (mosquito) AGAP008338-PA Anopheles gambiae (mosquito) XP_001120946.1 Apis mellifera (honey bee) 88566 Batrachochytrium dendrobatidis (chytrid fungus) 124884 Branchiostoma floridae (lancelet) ENSBTAP00000026065 Bos taurus (bovine) ENSCAFP00000002071 Canis familiaris (dog) ENSCINP00000022551 Ciona intestinalis (sea squirt) CPIJ010404 Culex pipens (mosquito) ENSCPOP00000001018 Cavia porcellus (guinea pig) 165907 Capitella spl (polychaete worm) ENSDARP00000068770 Danio rerio (zebra fish) ENSECAP00000020154 Equus caballus (horse) ENSGACP00000025313 Gymnopilus aculeatus (mushroom) ENSGALP00000020059 Gallus gallus (chicken) 174523 Hypsipyla robusta (cedar shoot borer) ENSP00000384667 Homo sapiens (human) 230313 Lottia gigantea (owl limpet) ENSMODP00000023798 Monodelphis domestica (gray opossum) ENSMMUP00000028392 Macaca mulatta (rhesus monkey) ENSMUSP00000047178 Mus musculus (house mouse) 237264 Nematostella vectensis (starlet anemone) ENSOANP00000023140 Ornithorynchus anatinus (platypus) ENSPPYP00000013172 Pongo pygmaeus (orangutan) ENSPTRP00000024725 Pan troglodytes (chimpanzee) ENSRNOP00000014878 Rattus norvegicus (norway rat) Smp_069890 Schistosoma mansoni (trematode parasite) XP_793966.2 Strongylocentrotus purpuratus (purple sea urchin) 53654 Trichoplax adhaerens (metazoa) XP_968243.1 Tribolium castaneum (red flour beetle) ENSTNIP00000003510 Tetraodon nigroviridis (green spotted pufferfish) ENSXETP00000013893 Xenopus tropicalis (frog) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • LH20465 FBgn0238536 FBgn0214293 FBgn0200901 FBgn0184672 FBgn0179760 FBgn0078782 FBgn0152687 FBgn0134245 FBgn0122434 FBgn0107298 FBgn0087175 CPIJ010404 BGIBMGA005551 ACYPI35305 GB19947 AGAP008338 AAEL001156 PB23430 GLEAN_15994
Stocks & Reagents
Stocks Listed in FlyBase ( 3 )
VDRC	v101425 P{KK109124}VIE-260B v22050 w1118; P{GD11599}v22050 v22051 w1118; P{GD11599}v22051/CyO
Genomic Clones ( 2 )
	BACR03E24 BACR10P09 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 17 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	AT27353
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT16610 AT16903 AT20143 AT22121 AT28636 LP06514 LP23941
Other clones	51500 214339.71 214413.68 bs21b06 bs74b06 bs77c08 EK158949 EK162450 EP03127
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0035952 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 39033
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments	FlyBase curator comment: the insertion in the "e04096" Exelixis line (PBac{RB}smge04096) was originally assigned to the CG5280 gene in FBrf0179797, resulting in the "CG5280e04096" (FBal0161296) allele. However, FBrf0184340 shows that the insertion is actually within smg. (Bloomington Drosophila Stock Center, 2004.11.6)
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_140021 RefSeq (Proteins) • NP_648278 DDBJ / EMBL / GenBank • AAF50335 AAM29313 AI257987 AI946121 AY113308 BF490773 Entrez Gene - A searchable database of RefSeq genes. • 39033 UniProtKB/Swiss-Prot • Q9VSS7 UniProtKB/TrEMBL • Q8MZ83
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Uncharacterised protein family UPF0193 (IPR007914)
Linkouts
	BioGRID - A database of protein and genetic interactions • 64437 DroID - A comprehensive database of gene and protein interactions. • FBgn0035952 DRSC - Results from RNAi screens. • FBgn0035952 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0035952 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG5280-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0035952 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 39033 InParanoid A subset of ortholog calls from InParanoid. • AAEL001156-PA Aedes aegypti (mosquito) AGAP008338-PA Anopheles gambiae (mosquito) XP_001120946.1 Apis mellifera (honey bee) 88566 Batrachochytrium dendrobatidis (chytrid fungus) 124884 Branchiostoma floridae (lancelet) ENSBTAP00000026065 Bos taurus (bovine) ENSCAFP00000002071 Canis familiaris (dog) ENSCINP00000022551 Ciona intestinalis (sea squirt) CPIJ010404 Culex pipens (mosquito) ENSCPOP00000001018 Cavia porcellus (guinea pig) 165907 Capitella spl (polychaete worm) ENSDARP00000068770 Danio rerio (zebra fish) ENSECAP00000020154 Equus caballus (horse) ENSGACP00000025313 Gymnopilus aculeatus (mushroom) ENSGALP00000020059 Gallus gallus (chicken) 174523 Hypsipyla robusta (cedar shoot borer) ENSP00000384667 Homo sapiens (human) 230313 Lottia gigantea (owl limpet) ENSMODP00000023798 Monodelphis domestica (gray opossum) ENSMMUP00000028392 Macaca mulatta (rhesus monkey) ENSMUSP00000047178 Mus musculus (house mouse) 237264 Nematostella vectensis (starlet anemone) ENSOANP00000023140 Ornithorynchus anatinus (platypus) ENSPPYP00000013172 Pongo pygmaeus (orangutan) ENSPTRP00000024725 Pan troglodytes (chimpanzee) ENSRNOP00000014878 Rattus norvegicus (norway rat) Smp_069890 Schistosoma mansoni (trematode parasite) XP_793966.2 Strongylocentrotus purpuratus (purple sea urchin) 53654 Trichoplax adhaerens (metazoa) XP_968243.1 Tribolium castaneum (red flour beetle) ENSTNIP00000003510 Tetraodon nigroviridis (green spotted pufferfish) ENSXETP00000013893 Xenopus tropicalis (frog) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 39033 modMine - Data generated by the modENCODE project. • FBgn0035952 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • LH20465 FBgn0238536 FBgn0214293 FBgn0200901 FBgn0184672 FBgn0179760 FBgn0078782 FBgn0152687 FBgn0134245 FBgn0122434 FBgn0107298 FBgn0087175 CPIJ010404 BGIBMGA005551 ACYPI35305 GB19947 AGAP008338 AAEL001156 PB23430 GLEAN_15994
Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	CG5280 (Keleman et al., 2009.8.5)
Name Synonym
Secondary FlyBase IDs
References ( 12 )
Supplementary material	The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518] Giot et al., 2003, Science 302(5651): Tables S1 to S7. [FBrf0166452]
Personal communication to FlyBase	Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] Bloomington Drosophila Stock Center, 2004.11.6, Exelixis insertion alleles that are not in FlyBase. Exelixis insertion alleles that are not in FlyBase. [FBrf0179797] Ryder, 2004.4.26, Exelixis CG deletion data. Exelixis CG deletion data. [FBrf0184335] Oliver, 2001.8.16, File from B. Oliver containing information on ESTs expressed in the Drosophila testis, described in Andrews et al., 2000, Genome Res. 10(12): 2030-2043 (FBrf0132348). File from B. Oliver containing information on ESTs expressed in the Drosophila testis, described in Andrews et al., 2000, Genome Res. 10(12): 2030-2043 (FBrf0132348). [FBrf0137492]
FlyBase analysis	FlyBase Curators, 2002-, Use of the ND evidence code for Gene Ontology (GO) terms in FlyBase. Use of the ND evidence code for Gene Ontology (GO) terms in FlyBase. [FBrf0159398]
Computer file	BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. Berkeley Drosophila Genome Project. [FBrf0125078]
Protein sequence record	Swiss-Prot Project Members, 2002.3.1, UniProtKB: Q9VSS7 Hypothetical protein EVG1 homolog. [FBrf0151107]