Gene model reviewed during 5.39
Gene model reviewed during 5.46
Gene model reviewed during 5.48
Gene model includes transcripts encoding non-overlapping portions of the full CDS.
Gene model includes transcripts encoding non-overlapping portions of the full CDS
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\PGRP-LA using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\PGRP-LA in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for identity of: PGRP-LA CG4384
Annotations CG18614, CG4361, CG4384 merged as CG32042 in release 3 of the genome annotation.
Source for merge of PGRP-LA CG18614 was a shared cDNA ( date:010720 ).
Source for identity of PGRP-LA CG4384 was sequence comparison ( date:001020 ).
Source for merge of CG18614 CG4361 was sequence comparison ( date:001104 ).
PGRP-LA is not required for the systemic production of antimicrobial peptides in the adult. It may have a role in positively regulating the antibacterial response in infected barrier epithelia: antimicrobial peptide gene expression is reduced in the tracheae of larvae and in the adult gut in PGRP-LA-deficient animals upon oral bacterial infection.