PGRP-LCx, PGRP-LCa, ird7
transmembrane receptor involved in antimicrobial response, recognizes bacterial toxins, tracheal cytotoxin (TCT), expressed in fat body and midgut
Please see the JBrowse view of Dmel\PGRP-LC for information on other features
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Gene model reviewed during 5.39
Low-frequency RNA-Seq exon junction(s) not annotated.
Annotated transcripts do not represent all possible combinations of alternative exons and/or alternative promoters.
Annotated transcripts do not represent all supported alternative splices within 5' UTR.
Gene model reviewed during 5.46
Gene model reviewed during 6.02
Gene model reviewed during 6.14
The group(s) of polypeptides indicated below share identical sequence to each other.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\PGRP-LC using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signals
View Dmel\PGRP-LC in GBrowse 23-29
Maps near to h.
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for identity of: PGRP-LC CG4432
Source for merge of: PGRP-LC ird7
Source for identity of PGRP-LC CG4432 was sequence comparison ( date:001020 ).
PGRP-LC binds strongly to all types of polymeric peptidoglycan and to monomeric TCT.
Identification: as a mutation that fails to induce expression of Ecol\lacZDpt.PR normally in response to infection. 2 alleles have been obtained.