FlyBase Gene Report: Dmel\phol

General Information

Symbol

Dmel\phol

Species

D. melanogaster

Name

pleiohomeotic like

Annotation Symbol

CG3445

Feature Type

protein_coding_gene

FlyBase ID

FBgn0035997

Gene Model Status

Current

Stock Availability

10 publicly available

Gene Summary

pleiohomeotic like (phol) encodes a zinc-finger protein that is 80% identical in the zinc-finger region to the product of pho. The product of phol plays a role in Polycomb group protein recruitment to Polycomb response elements, but it has additional roles, most likely as a transcriptional activator. [Date last reviewed: 2019-03-14] (FlyBase Gene Snapshot)

All Summaries

Gene Snapshot
Alliance
Auto summary
Gene Group
Interactive Fly

Also Known As

Pho-like

Key Links

Genomic Location

Cytogenetic map

67B7-67B8

Sequence location

3L:9,452,803..9,456,281 [-]

Recombination map

3-29

RefSeq locus

NT_037436 REGION:9452803..9456281

Sequence

Get Decorated FASTA

Genomic Maps

JBrowse GBrowse

Help me choose

Other Genome Views

The following external sites may use different assemblies or annotations than FlyBase.

Function

GO Summary Ribbons

Gene Ontology (GO) Annotations (9 terms)

Molecular Function (4 terms)

Terms Based on Experimental Evidence (1 term)

CV Term

Evidence

References

enables sequence-specific DNA binding

inferred from direct assay

(Brown et al., 2003)

Terms Based on Predictions or Assertions (3 terms)

CV Term

Evidence

References

enables DNA binding

traceable author statement

(Levine et al., 2004)

enables DNA-binding transcription factor activity, RNA polymerase II-specific

inferred from biological aspect of ancestor with PANTHER:PTN000360827

(assigned by GO_Central )

(Gaudet et al., 2011)

enables RNA polymerase II cis-regulatory region sequence-specific DNA binding

inferred from biological aspect of ancestor with PANTHER:PTN000360827

(assigned by GO_Central )

(Gaudet et al., 2011)

Biological Process (2 terms)

Terms Based on Experimental Evidence (1 term)

CV Term

Evidence

References

involved_in gene silencing

inferred from genetic interaction with FLYBASE:pho; FB:FBgn0002521

(Brown et al., 2003)

Terms Based on Predictions or Assertions (1 term)

CV Term

Evidence

References

involved_in regulation of transcription by RNA polymerase II

inferred from biological aspect of ancestor with PANTHER:PTN000360827

(assigned by GO_Central )

(Gaudet et al., 2011)

Cellular Component (3 terms)

Terms Based on Experimental Evidence (1 term)

CV Term

Evidence

References

located_in nucleus

inferred from direct assay

(Klymenko et al., 2006)

Terms Based on Predictions or Assertions (2 terms)

CV Term

Evidence

References

part_of PcG protein complex

inferred from biological aspect of ancestor with PANTHER:PTN000360827

(assigned by GO_Central )

(Gaudet et al., 2011)

part_of transcription regulator complex

inferred from biological aspect of ancestor with PANTHER:PTN000360827

(assigned by GO_Central )

(Gaudet et al., 2011)

Gene Group (FlyBase)

POLYCOMB GROUP RECRUITERS/DNA-BINDING PROTEINS

PHO REPRESSIVE COMPLEX

C2H2 ZINC FINGER TRANSCRIPTION FACTORS

Protein Family (UniProt)

Protein Signatures (InterPro)

Summaries

Gene Snapshot

Gene Group (FlyBase)

POLYCOMB GROUP RECRUITERS/DNA-BINDING PROTEINS -: The Polycomb group (PcG) proteins are epigenetic regulators, best characterized for the repression of Hox gene expression. In Drosophila, PcG proteins repress their target genes by binding to specific DNA elements called Polycomb Response Elements (PREs). PcG DNA binding proteins contribute to the recruitment of Polycomb complexes to PREs. (Adapted from FBrf0228921).
PHO REPRESSIVE COMPLEX -: In Drosophila, the Pho repressive complex (PhoRC) can bind Polycomb Response Elements (PREs) and recruit Polycomb repressive complexes. (Adapted from FBrf0190547 and FBrf0220020).
C2H2 ZINC FINGER TRANSCRIPTION FACTORS -: Zinc finger C2H2 transcription factors are sequence-specific DNA binding proteins that regulate transcription. They possess DNA-binding domains that are formed from repeated Cys₂His₂ zinc finger motifs. (Adapted from PMID:1835093, FBrf0220103 and FBrf0155739).

Gene Model and Products

Number of Transcripts

Number of Unique Polypeptides

Please see the JBrowse view of Dmel\phol for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)

Isoform displayed:

Pfam protein domains

InterPro name

classification

start

end

Protein Domains (via SMART)

Isoform displayed:

SMART protein domains

InterPro name

classification

start

end

Comments on Gene Model

Gene model reviewed during 5.45

Gene model reviewed during 5.56

Sequence Ontology: Class of Gene

gene_with_edited_transcript

(Graveley et al., 2011)

nuclear_gene

protein_coding_gene

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Assoc. CDS (aa)

phol-RA

FBtr0076475

NM_140060

3139

669

phol-RB

FBtr0345600

NM_001300076

3384

669

Additional Transcript Data and Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

RefSeq ID

GenBank

phol-PA

FBpp0076203

73.2

669

4.64

NP_648317

AAF50265

phol-PB

FBpp0311669

73.2

669

4.64

NP_001287005

AHN58030

Polypeptides with Identical Sequences

The group(s) of polypeptides indicated below share identical sequence to each other.

669 aa isoforms: phol-PA, phol-PB

Additional Polypeptide Data and Comments

Reported size (kDa)

Comments

External Data

Crossreferences

InterPro - A database of protein families, domains and functional sites

Linkouts

Sequences Consistent with the Gene Model

Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\phol using the Feature Mapper tool.

External Data

Crossreferences

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

phol_1

Linkouts

Expression Data

Expression Summary Ribbons

Colored tiles in ribbon indicate that expression data has been curated by FlyBase for that anatomical location. Colorless tiles indicate that there is no curated data for that location.

For complete stage-specific expression data, view the modENCODE Development RNA-Seq section under High-Throughput Expression below.

Transcript Expression

in situ

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 1 -- 3

organism

Comment: maternally deposited

(Fisher et al., 2012)

embryonic stage 4 -- 6

organism | ubiquitous

(Fisher et al., 2012)

embryonic stage 7 -- 8

organism | ubiquitous

(Fisher et al., 2012)

embryonic stage 9 -- 10

organism | ubiquitous

(Fisher et al., 2012)

embryonic stage 11 -- 12

organism | ubiquitous

(Fisher et al., 2012)

embryonic stage 13 -- 16

organism | ubiquitous

(Fisher et al., 2012)

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Evidence

References

located_in nucleus

inferred from direct assay

(Klymenko et al., 2006)

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

GBrowse - Visual display of RNA-Seq signals

View Dmel\phol in GBrowse 2

RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region

View exonic expression by developmental stage for Dmel\phol

View exonic expression by tissue for Dmel\phol

Bulk Downloads

RNA-Seq RPKM values for all genes

Reference

See Gelbart and Emmert, 2013 for analysis details and data files for all genes.

Developmental Proteome: Life Cycle

Developmental Proteome: Embryogenesis

External Data and Images

Linkouts

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0035997

DRscDB

39095/tissue=All

EMBL-EBI Single Cell Expression Atlas

FBgn0035997

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

CG3445-RA

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG3445

Flygut - An atlas of the Drosophila adult midgut

FBgn0035997

Images

FlyBase Wiki

Image Based Resources

Alleles, Insertions, Transgenic Constructs, and Aberrations

Classical and Insertion Alleles ( 5 )

For All Classical and Insertion Alleles Show

Other relevant insertions

Transgenic Constructs ( 6 )

For All Alleles Carried on Transgenic Constructs Show

Transgenic constructs containing/affecting coding region of phol

Transgenic constructs containing regulatory region of phol

Aberrations (Deficiencies and Duplications) ( 0 )

Inferred from experimentation ( 0 )

Inferred from location ( 0 )

Alleles Representing Disease-Implicated Variants

Phenotypes

For more details about a specific phenotype click on the relevant allele symbol.

Lethality

Allele

lethal | embryonic stage | germline clone | maternal effect | recessive

lethal | embryonic stage | maternal effect | recessive

lethal | male limited, with Scer\GAL4^Bx-MS1096

phol^{UAS.ORF.GW.Tag:HA}

lethal | male limited | cold sensitive, with Scer\GAL4^Bx-MS1096

phol^{UAS.ORF.GW.Tag:HA}

partially lethal, with Scer\GAL4^Mef2.PR

phol^GD10970

viable

viable, with Scer\GAL4^- :

phol^EP559

viable, with Dcr-2^UAS.cDa, Scer\GAL4^elav.PLu

phol^GD10970

viable, with Scer\GAL4^pnr-MD237

phol^GD10970

viable, with Scer\GAL4^tin.CΔ4

phol^GD10970

Sterility

Allele

female sterile | recessive

fertile, with Scer\GAL4^- :

phol^EP559

male fertile

Other Phenotypes

Allele

visible | female limited, with Scer\GAL4^Bx-MS1096

phol^{UAS.ORF.GW.Tag:HA}

visible | female limited | cold sensitive, with Scer\GAL4^Bx-MS1096

phol^{UAS.ORF.GW.Tag:HA}

visible | male limited, with Scer\GAL4^Bx-MS1096

phol^GD10970

Phenotype manifest in

Allele

wing | female limited, with Scer\GAL4^Bx-MS1096

phol^{UAS.ORF.GW.Tag:HA}

wing | female limited | cold sensitive, with Scer\GAL4^Bx-MS1096

phol^{UAS.ORF.GW.Tag:HA}

wing | male limited, with Scer\GAL4^Bx-MS1096

phol^GD10970

Orthologs

Downloads

Download All DIOPT Orthologs

Download All OrthoDB Orthologs

Human Orthologs (via DIOPT v8.0)

Homo sapiens (Human) (3)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Hsap\YY1

7 of 15

Yes

Hsap\YY2

7 of 15

Yes

Hsap\ZFP42

4 of 15

Model Organism Orthologs (via DIOPT v8.0)

Mus musculus (laboratory mouse) (5)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Mmus\Yy1

7 of 15

Yes

Mmus\Yy2

4 of 15

Mmus\Zfp42

4 of 15

Yes

Mmus\Gm12845

1 of 15

Yes

Mmus\Zfp143

1 of 15

Yes

Rattus norvegicus (Norway rat) (4)

Rnor\Yy1

6 of 13

Yes

Rnor\Yy2

3 of 13

Rnor\Zfp42l

2 of 13

Yes

Rnor\Zfp42

1 of 13

Yes

Xenopus tropicalis (Western clawed frog) (1)

Xtro\yy1

4 of 12

Yes

Danio rerio (Zebrafish) (2)

Drer\yy1a

7 of 15

Yes

Drer\yy1b

7 of 15

Yes

Caenorhabditis elegans (Nematode, roundworm) (1)

Cele\ztf-17

2 of 15

Yes

Arabidopsis thaliana (thale-cress) (1)

Atha\YY1

3 of 9

Yes

Saccharomyces cerevisiae (Brewer's yeast) (2)

Scer\NRG1

1 of 15

Yes

Scer\NRG2

1 of 15

Yes

Schizosaccharomyces pombe (Fission yeast) (0)

No records found.

Ortholog(s) in Drosophila Species (via OrthoDB v9.1) ( EOG091908FC )

Organism

Common Name

Gene

AAA Syntenic Ortholog

Multiple Dmel Genes in this Orthologous Group

Drosophila suzukii

Spotted wing Drosophila

Drosophila simulans

Drosophila sechellia

Drosophila erecta

Drosophila yakuba

Drosophila ananassae

Drosophila pseudoobscura pseudoobscura

Dpse\GA17456

Drosophila persimilis

Dper\GL17968

Drosophila willistoni

Dwil\GK20506

Drosophila virilis

Dvir\GJ13188

Drosophila mojavensis

Dmoj\GI13359

Drosophila grimshawi

Dgri\GH16213

Orthologs in non-Drosophila Dipterans (via OrthoDB v9.1) ( EOG091504VN )

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Musca domestica

House fly

Mdoa\17018872

Glossina morsitans

Tsetse fly

Gmor\GMOY011086

Lucilia cuprina

Australian sheep blowfly

Lcup\FF38_07101

Orthologs in non-Dipteran Insects (via OrthoDB v9.1) ( EOG090W02BX )

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Bombyx mori

Silkmoth

Bmor\BGIBMGA011179

Danaus plexippus

Monarch butterfly

Dple\DPOGS200468-PA

Heliconius melpomene

Postman butterfly

Hmel\HMEL010415

Apis florea

Little honeybee

Aflo\2355231940

Apis mellifera

Western honey bee

Amel\GB49343

Bombus impatiens

Common eastern bumble bee

Bimp\BIMP22139

Bombus terrestris

Buff-tailed bumblebee

Bter\15213295

Linepithema humile

Argentine ant

Lhum\LH14355

Megachile rotundata

Alfalfa leafcutting bee

Mrot\MROTU:001aef

Nasonia vitripennis

Parasitic wasp

Nvit\Nasvi2EG000131

Dendroctonus ponderosae

Mountain pine beetle

Dpod\YQE_09404

Tribolium castaneum

Red flour beetle

Tcas\pho

Pediculus humanus

Human body louse

Phum\PHUM284920

Rhodnius prolixus

Kissing bug

Rpro\RPRC009167

Cimex lectularius

Bed bug

Clec\CLEC004566

Cimex lectularius

Bed bug

Clec\CLEC004565

Acyrthosiphon pisum

Pea aphid

Apim\ACYPI007734

Zootermopsis nevadensis

Nevada dampwood termite

Znev\Znev_08817

Orthologs in non-Insect Arthropods (via OrthoDB v9.1) ( EOG090X029J )

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Strigamia maritima

European centipede

Smar\SMAR005684

Ixodes scapularis

Black-legged tick

Isca\ISCW010258

Stegodyphus mimosarum

African social velvet spider

Smim\KFM82896.1

Stegodyphus mimosarum

African social velvet spider

Smim\KFM73407.1

Stegodyphus mimosarum

African social velvet spider

Smim\KFM73406.1

Tetranychus urticae

Two-spotted spider mite

Turt\tetur09g00130

Tetranychus urticae

Two-spotted spider mite

Turt\tetur09g00290

Daphnia pulex

Water flea

Dpux\DAPPUDRAFT_59123

Orthologs in non-Arthropod Metazoa (via OrthoDB v9.1) ( EOG091G03FM )

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Strongylocentrotus purpuratus

Purple sea urchin

Spur\Sp-Yyi

Ciona intestinalis

Vase tunicate

Cint\ENSCING00000018982

Gallus gallus

Domestic chicken

Ggal\YY1

Paralogs

Downloads

Download All DIOPT Paralogs

Paralogs (via DIOPT v8.0)

Drosophila melanogaster (Fruit fly) (1)

Gene Symbol

Score

Source

Alignment

pho

6 of 10

Human Disease Associations

FlyBase Human Disease Model Reports

Disease Model Summary Ribbon

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Allele

Disease

Evidence

References

Potential Models Based on Orthology ( 0 )

Human Ortholog

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Allele

Disease

Interaction

References

Disease Associations of Human Orthologs (via DIOPT v8.0 and OMIM)

Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.

Homo sapiens (Human)

Gene name

Score

OMIM

OMIM Phenotype

DO term

Complementation?

Transgene?

YY1; YY1 transcription factor

7 of 15

600013

GABRIELE-DE VRIES SYNDROME; GADEVS

YY2; YY2 transcription factor

7 of 15

300570

ZFP42; ZFP42 zinc finger protein

4 of 15

614572

Functional Complementation Data

Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.

Interactions

Summary of Physical Interactions

esyN Network Diagram

Interactions Browser

View in Interactions Browser

Please see the Physical Interaction reports below for full details

protein-protein

Physical Interaction

Assay

References

phol - Ank2

two hybrid

(Hu et al., 2017.6.13)

phol - CG11906

two hybrid array

(Shokri et al., 2019)

phol - CG14407

two hybrid

(Hu et al., 2017.6.13)

phol - CG2712

two hybrid array

(Shokri et al., 2019)

phol - CG31955

two hybrid array

(Shokri et al., 2019)

phol - CG3726

two hybrid array

(Shokri et al., 2019)

phol - CG4730

two hybrid array

(Shokri et al., 2019)

phol - CG9650

two hybrid array

(Shokri et al., 2019)

phol - Cenp-C

two hybrid array

(Shokri et al., 2019)

phol - Fkbp12

anti tag coimmunoprecipitation, peptide massfingerprinting, experimental knowledge based

(Rhee et al., 2014)

phol - MBD-R2

two hybrid array

(Shokri et al., 2019)

phol - Sfmbt

anti tag coimmunoprecipitation, molecular weight estimation by staining, anti bait coimmunoprecipitation, western blot

(Klymenko et al., 2006)

phol - Sgf11

anti tag coimmunoprecipitation, peptide massfingerprinting, experimental knowledge based

(Rhee et al., 2014)

phol - esc

pull down, autoradiography

(Wang et al., 2004)

phol - gcm

two hybrid

(Jacques et al., 2009)

phol - h

two hybrid array

(Shokri et al., 2019)

phol - kn

two hybrid array

(Shokri et al., 2019)

phol - sens-2

two hybrid array

(Shokri et al., 2019)

phol - sr

two hybrid array

(Shokri et al., 2019)

phol - sv

two hybrid array

(Shokri et al., 2019)

phol - unpg

two hybrid array

(Shokri et al., 2019)

Summary of Genetic Interactions

esyN Network Diagram

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

External Data

Linkouts

BioGRID - A database of protein and genetic interactions.

64488

DroID - A comprehensive database of gene and protein interactions.

FBgn0035997

InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.

39095

MIST (protein-protein) - An integrated Molecular Interaction Database

phol

Pathways

Signaling Pathways (FlyBase)

Metabolic Pathways

External Data

Linkouts

Genomic Location and Detailed Mapping Data

Chromosome (arm)

Recombination map

3-29

Cytogenetic map

67B7-67B8

Sequence location

3L:9,452,803..9,456,281 [-]

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

67B7-67B8

Limits computationally determined from genome sequence between P{EP}Hsp26^EP3336&P{EP}Hsp26^EP3315 and P{PZ}fry⁰²²⁴⁰

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

3-29

(FlyBase, 2016)

3-23.0

(Comeron et al., 2012)

Left of (cM)

Right of (cM)

Notes

Stocks and Reagents

Stocks (10)

Bloomington

43365

w^*; P{GSV1}phol^C403

17180

w¹¹¹⁸; P{EP}phol^EP559

66456

y¹ w^*; P{phol-GFP.FPTB}attP40

24164

y¹ w^*; phol^81A/TM3, Ser¹ y⁺

64945

y¹ sc^* v¹ sev²¹; P{TRiP.HMC05819}attP40

15275

y¹; P{SUPor-P}phol^KG10524 ry⁵⁰⁶/TM3, Sb¹ Ser¹

FlyORF

F000268

M{UAS-phol.ORF.3xHA.GW}ZH-86Fb

Kyoto

111700

y^d2 w¹¹¹⁸ P{ey-FLP.N}2 P{5xglBS-lacZ.38-1}TPN1; P{SUPor-P}phol^KG10524 P{neoFRT}80B/TM6B, P{Car20y}TPN1, Tb¹

VDRC

v26196

w¹¹¹⁸; P{GD10970}v26196

v341724

P{hsFLP}1, y¹ w¹¹¹⁸; P{HD_CFD00835}attP40/CyO-GFP

Genomic Clones (12)

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones (33)

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequenced

BDGP DGC clones

LD31045

Other clones

Drosophila Genomics Resource Center cDNA clones

For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

FBgn0035997

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi and Array Information

Linkouts

DRSC - Results frm RNAi screens

FBgn0035997

GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents

39095

Antibody Information

Laboratory Generated Antibodies

Commercially Available Antibodies

Other Information

Relationship to Other Genes

Source for database identify of

Source for identity of: phol CG3445

(Kassis, 2003.2.10)

Source for database merge of

Additional comments

Other Comments

DNA-protein interactions: genome-wide binding profile assayed for phol protein in Kc167 cells; see Chromatin_types_NKI collection report. Individual protein-binding experiments listed under "Samples" at GEO_GSE22069 (http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE22069).

(Filion et al., 2010)

pho and phol act redundantly to repress homeotic genes.

(Brown et al., 2003)

Origin and Etymology

Discoverer

Etymology

Identification

External Crossreferences and Linkouts ( 37 )

Sequence Crossreferences

NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.

39095

GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.

GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.

RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.

UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information

Q9VSZ3

Other crossreferences

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0035997

Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones

FBgn0035997

DRscDB

39095/tissue=All

EMBL-EBI Single Cell Expression Atlas

FBgn0035997

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

phol_1

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG3445

Flygut - An atlas of the Drosophila adult midgut

FBgn0035997

GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents

39095

InterPro - A database of protein families, domains and functional sites

KEGG Genes - Molecular building blocks of life in the genomic space.

Dmel_CG3445

MARRVEL_MODEL

39095

modMine - A data warehouse for the modENCODE project

FBgn0035997

SignaLink - A signaling pathway resource with multi-layered regulatory networks.

Q9VSZ3

Linkouts

BioGRID - A database of protein and genetic interactions.

64488

DroID - A comprehensive database of gene and protein interactions.

FBgn0035997

DRSC - Results frm RNAi screens

FBgn0035997

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

CG3445-RA

FlyCyc Genes - Genes from a BioCyc PGDB for Dmel

FBGN0035997

FlyMine - An integrated database for Drosophila genomics

FBgn0035997

InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.

39095

MIST (protein-protein) - An integrated Molecular Interaction Database

phol

Synonyms and Secondary IDs (12)

Reported As

Symbol Synonym

CG3445

(Neuert et al., 2017, Perkins et al., 2009, Molnar et al., 2006)

PHOL

(Bajusz et al., 2015, Grossniklaus and Paro, 2014, Kahn et al., 2014, Mason-Suares et al., 2013, Filion et al., 2010, Schuettengruber et al., 2009, Savla et al., 2008, Schwartz and Pirrotta, 2007)

Phol

(Chetverina et al., 2020, McElroy et al., 2014, Huen and Russell, 2010, Klymenko et al., 2006, Brown et al., 2005)

Name Synonyms

PHO-LIKE

(Savla et al., 2008)

PHO-like

(Mason-Suares et al., 2013)

Pho-like

(McElroy et al., 2014, Ringrose and Paro, 2007, Klymenko et al., 2006, Muller and Kassis, 2006)

Pleiohomeotic like

(Brown et al., 2005)

Pleiohomeotic-like

(Huen and Russell, 2010, Jacques et al., 2009, Schuettengruber et al., 2009)

pho-like

(McElroy et al., 2014, Lehmann, 2004, Lund and van Lohuizen, 2004)

pleiohomeotic like

(Suganuma and Workman, 2010, Kassis et al., 2003)

pleiohomeotic-like

(Kim et al., 2008)

Secondary FlyBase IDs

Datasets (1)

Study focus (1)

Experimental Role

Project

Project Type

Title

transgene_used

FBGSE22069

genome binding

Protein profiling reveals five principal chromatin types in Drosophila cells.

References (83)

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