Gene Dmel\CG3335

Help

Close All Open All

General Information

Symbol

Dmel\CG3335

Species

D. melanogaster

Name

Annotation symbol

CG3335

Feature type

protein_coding_gene

FlyBase ID

FBgn0036018

Gene Model Status

Current

Stock availability

2 publicly available

Genomic Location

Chromosome (arm)

Recombination map

Cytogenetic map

67C2-67C2

Sequence location

3L:9,617,383..9,620,425 [+]

Genomic Maps

Select View:

modENCODE GBrowse

Summary Information

Automatically generated summary

See sections below for more information

This gene is referred to in FlyBase by the symbol Dmel\CG3335 (FBgn0036018). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: mRNA binding; helicase activity. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Nucleotide-binding, alpha-beta plait; RNA recognition motif domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 00-12 and 18-24 hour embryonic stages, in adult female stages. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: larval central nervous system, adult female reproductive system, adult male accessory gland. Comments on Affy2 ProbeSet: ProbeSet 1631433_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG3335. Gene sequence location is 3L:9617383..9620425.

Recent Updates

Description

What does this section display?

This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms).

What does this section not display?

This section does not currently display links that were removed or gene model changes.

Update Feed

Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.

FB2012_01

Sequence features

BKN21359

HFA10358

FB2011_10

Controlled Vocabulary Terms

day 6 of adulthood

day 5 of adulthood

male

day 7 of adulthood

spermatozoon

All updates

Click here to see a list of all updates to this record from FB2010_08 and on.

Detailed Mapping Data

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

67C2-67C2

Limits computationally determined from genome sequence between P{EP}Hsp26^EP3336&P{EP}Hsp26^EP3315 and P{PZ}fry⁰²²⁴⁰

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

Left of (cM)

Right of (cM)

Notes

Gene Model & Products

Please see the GBrowse view of Dmel\CG3335 for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Comments on Gene Model

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Associated CDS (aa)

CG3335-RA

FBtr0076383

NM_140080

2884

918

Additional Transcript Data & Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

RefSeq ID

GenBank protein

CG3335-PA

FBpp0076112

103.9

918

7.30

NP_648337

AAF50237

Additional Polypeptide Data & Comments

Reported size (kDa)

Comments

External Data

Linkouts

Crossreferences

InterPro domains - A database of protein families, domains, and functional sites

•

RNA recognition motif domain (IPR000504)

Nucleotide-binding, alpha-beta plait (IPR012677)

Sequences Consistent with the Gene Model

DDBJ /
EMBL /
GenBank

DNA sequence

Protein sequence

Name

Mapped Features

Mapped Features have been reorganized, please see this article for details.

Additional mapped features and mutations can be found on GBrowse or related reports.

Type

Symbol & Location

Additional Notes

References

External Data

Linkouts

Crossreferences

Expression Data

Transcript Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Notes

Polypeptide Expression

mass spectroscopy

Stage

Tissue/Position (including subcellular localization)

Reference

day 5 of adulthood & male -- day 7 of adulthood & male

spermatozoon

(Wasbrough et al., 2010)

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Notes

High-Throughput Expression Data

Untitled Document detailed view

See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.

modENCODE Temporal Expression Data for FBgn0036018

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	max expr for FBgn0036018
	Very low expression bin max
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 00-12 and 18-24 hour embryonic stages, in adult female stages.
[download data (TSV)]

Guide to modENCODE expression level colors
	No expression (0 - 0)
	Extremely low expression (1 - 10)
	Very low expression (11 - 100)
	Low expression (101 - 400)
	Moderate expression (401 - 1400)
	Moderately high expression (1401 - 4000)
	High expression (4001 - 10000)
	Very high expression (10001 - 100000)
	Extremely high expression (100001 - 2000000)

Linear, scaled to maximum FBgn0036018 expression level
Developmental Stage		Expression Level
embryo 00-02hr		1729
embryo 02-04hr		2455
embryo 04-06hr		2232
embryo 06-08hr		2301
embryo 08-10hr		2218
embryo 10-12hr		1378
embryo 12-14hr		1314
embryo 14-16hr		787
embryo 16-18hr		856
embryo 18-20hr		731
embryo 20-22hr		2044
embryo 22-24hr		1848
larva L1		1093
larva L2		656
larva L3 12hr old		446
larva L3 puffstage 1-2		309
larva L3 puffstage 3-6		361
larva L3 puffstage 7-9		396
white prepupae new		309
white prepupae 12hr		320
white prepupae 24hr		335
pupae 2d postWPP		324
pupae 3d postWPP		199
pupae 4d postWPP		198
adult male 01day		245
adult male 05day		292
adult male 30day		227
adult female 01day		744
adult female 05day		1728
adult female 30day		1682
Expression Level Scale		None Extremely low Very low Low Moderate Moderately high

Linear, scaled to Very low expression
Developmental Stage		Expression Level
embryo 00-02hr		(1729)
embryo 02-04hr		(2455)
embryo 04-06hr		(2232)
embryo 06-08hr		(2301)
embryo 08-10hr		(2218)
embryo 10-12hr		(1378)
embryo 12-14hr		(1314)
embryo 14-16hr		(787)
embryo 16-18hr		(856)
embryo 18-20hr		(731)
embryo 20-22hr		(2044)
embryo 22-24hr		(1848)
larva L1		(1093)
larva L2		(656)
larva L3 12hr old		(446)
larva L3 puffstage 1-2		(309)
larva L3 puffstage 3-6		(361)
larva L3 puffstage 7-9		(396)
white prepupae new		(309)
white prepupae 12hr		(320)
white prepupae 24hr		(335)
pupae 2d postWPP		(324)
pupae 3d postWPP		(199)
pupae 4d postWPP		(198)
adult male 01day		(245)
adult male 05day		(292)
adult male 30day		(227)
adult female 01day		(744)
adult female 05day		(1728)
adult female 30day		(1682)
Expression Level Scale		None Extremely low Very low Low

Linear, scaled to Moderate expression
Developmental Stage		Expression Level
embryo 00-02hr		(1729)
embryo 02-04hr		(2455)
embryo 04-06hr		(2232)
embryo 06-08hr		(2301)
embryo 08-10hr		(2218)
embryo 10-12hr		1378
embryo 12-14hr		1314
embryo 14-16hr		787
embryo 16-18hr		856
embryo 18-20hr		731
embryo 20-22hr		(2044)
embryo 22-24hr		(1848)
larva L1		1093
larva L2		656
larva L3 12hr old		446
larva L3 puffstage 1-2		309
larva L3 puffstage 3-6		361
larva L3 puffstage 7-9		396
white prepupae new		309
white prepupae 12hr		320
white prepupae 24hr		335
pupae 2d postWPP		324
pupae 3d postWPP		199
pupae 4d postWPP		198
adult male 01day		245
adult male 05day		292
adult male 30day		227
adult female 01day		744
adult female 05day		(1728)
adult female 30day		(1682)
Expression Level Scale		None Extremely low Very low Low Moderate Moderately high

Linear, scaled to High expression
Developmental Stage		Expression Level
embryo 00-02hr		1729
embryo 02-04hr		2455
embryo 04-06hr		2232
embryo 06-08hr		2301
embryo 08-10hr		2218
embryo 10-12hr		1378
embryo 12-14hr		1314
embryo 14-16hr		787
embryo 16-18hr		856
embryo 18-20hr		731
embryo 20-22hr		2044
embryo 22-24hr		1848
larva L1		1093
larva L2		656
larva L3 12hr old		446
larva L3 puffstage 1-2		309
larva L3 puffstage 3-6		361
larva L3 puffstage 7-9		396
white prepupae new		309
white prepupae 12hr		320
white prepupae 24hr		335
pupae 2d postWPP		324
pupae 3d postWPP		199
pupae 4d postWPP		198
adult male 01day		245
adult male 05day		292
adult male 30day		227
adult female 01day		744
adult female 05day		1728
adult female 30day		1682
Expression Level Scale		None Extremely low Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Developmental Stage		Expression Level
embryo 00-02hr		1729
embryo 02-04hr		2455
embryo 04-06hr		2232
embryo 06-08hr		2301
embryo 08-10hr		2218
embryo 10-12hr		1378
embryo 12-14hr		1314
embryo 14-16hr		787
embryo 16-18hr		856
embryo 18-20hr		731
embryo 20-22hr		2044
embryo 22-24hr		1848
larva L1		1093
larva L2		656
larva L3 12hr old		446
larva L3 puffstage 1-2		309
larva L3 puffstage 3-6		361
larva L3 puffstage 7-9		396
white prepupae new		309
white prepupae 12hr		320
white prepupae 24hr		335
pupae 2d postWPP		324
pupae 3d postWPP		199
pupae 4d postWPP		198
adult male 01day		245
adult male 05day		292
adult male 30day		227
adult female 01day		744
adult female 05day		1728
adult female 30day		1682
Expression Level Scale		None Extremely low Very low Low Moderate Moderately high High Very high Extremely high

log, scaled to maximum FBgn0036018 expression level
Developmental Stage		Expression Level
embryo 00-02hr		1729
embryo 02-04hr		2455
embryo 04-06hr		2232
embryo 06-08hr		2301
embryo 08-10hr		2218
embryo 10-12hr		1378
embryo 12-14hr		1314
embryo 14-16hr		787
embryo 16-18hr		856
embryo 18-20hr		731
embryo 20-22hr		2044
embryo 22-24hr		1848
larva L1		1093
larva L2		656
larva L3 12hr old		446
larva L3 puffstage 1-2		309
larva L3 puffstage 3-6		361
larva L3 puffstage 7-9		396
white prepupae new		309
white prepupae 12hr		320
white prepupae 24hr		335
pupae 2d postWPP		324
pupae 3d postWPP		199
pupae 4d postWPP		198
adult male 01day		245
adult male 05day		292
adult male 30day		227
adult female 01day		744
adult female 05day		1728
adult female 30day		1682
Expression Level Scale		None Extremely low Very low Low Moderate Moderately high High

log, scaled to Very low expression
Developmental Stage		Expression Level
embryo 00-02hr		(1729)
embryo 02-04hr		(2455)
embryo 04-06hr		(2232)
embryo 06-08hr		(2301)
embryo 08-10hr		(2218)
embryo 10-12hr		(1378)
embryo 12-14hr		(1314)
embryo 14-16hr		(787)
embryo 16-18hr		(856)
embryo 18-20hr		(731)
embryo 20-22hr		(2044)
embryo 22-24hr		(1848)
larva L1		(1093)
larva L2		(656)
larva L3 12hr old		(446)
larva L3 puffstage 1-2		(309)
larva L3 puffstage 3-6		(361)
larva L3 puffstage 7-9		(396)
white prepupae new		(309)
white prepupae 12hr		(320)
white prepupae 24hr		(335)
pupae 2d postWPP		(324)
pupae 3d postWPP		(199)
pupae 4d postWPP		(198)
adult male 01day		(245)
adult male 05day		(292)
adult male 30day		(227)
adult female 01day		(744)
adult female 05day		(1728)
adult female 30day		(1682)
Expression Level Scale		None Extremely low Very low Low

log, scaled to Moderate expression
Developmental Stage		Expression Level
embryo 00-02hr		1729
embryo 02-04hr		2455
embryo 04-06hr		2232
embryo 06-08hr		2301
embryo 08-10hr		2218
embryo 10-12hr		1378
embryo 12-14hr		1314
embryo 14-16hr		787
embryo 16-18hr		856
embryo 18-20hr		731
embryo 20-22hr		2044
embryo 22-24hr		1848
larva L1		1093
larva L2		656
larva L3 12hr old		446
larva L3 puffstage 1-2		309
larva L3 puffstage 3-6		361
larva L3 puffstage 7-9		396
white prepupae new		309
white prepupae 12hr		320
white prepupae 24hr		335
pupae 2d postWPP		324
pupae 3d postWPP		199
pupae 4d postWPP		198
adult male 01day		245
adult male 05day		292
adult male 30day		227
adult female 01day		744
adult female 05day		1728
adult female 30day		1682
Expression Level Scale		None Extremely low Very low Low Moderate Moderately high

log, scaled to High expression
Developmental Stage		Expression Level
embryo 00-02hr		1729
embryo 02-04hr		2455
embryo 04-06hr		2232
embryo 06-08hr		2301
embryo 08-10hr		2218
embryo 10-12hr		1378
embryo 12-14hr		1314
embryo 14-16hr		787
embryo 16-18hr		856
embryo 18-20hr		731
embryo 20-22hr		2044
embryo 22-24hr		1848
larva L1		1093
larva L2		656
larva L3 12hr old		446
larva L3 puffstage 1-2		309
larva L3 puffstage 3-6		361
larva L3 puffstage 7-9		396
white prepupae new		309
white prepupae 12hr		320
white prepupae 24hr		335
pupae 2d postWPP		324
pupae 3d postWPP		199
pupae 4d postWPP		198
adult male 01day		245
adult male 05day		292
adult male 30day		227
adult female 01day		744
adult female 05day		1728
adult female 30day		1682
Expression Level Scale		None Extremely low Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Developmental Stage		Expression Level
embryo 00-02hr		1729
embryo 02-04hr		2455
embryo 04-06hr		2232
embryo 06-08hr		2301
embryo 08-10hr		2218
embryo 10-12hr		1378
embryo 12-14hr		1314
embryo 14-16hr		787
embryo 16-18hr		856
embryo 18-20hr		731
embryo 20-22hr		2044
embryo 22-24hr		1848
larva L1		1093
larva L2		656
larva L3 12hr old		446
larva L3 puffstage 1-2		309
larva L3 puffstage 3-6		361
larva L3 puffstage 7-9		396
white prepupae new		309
white prepupae 12hr		320
white prepupae 24hr		335
pupae 2d postWPP		324
pupae 3d postWPP		199
pupae 4d postWPP		198
adult male 01day		245
adult male 05day		292
adult male 30day		227
adult female 01day		744
adult female 05day		1728
adult female 30day		1682
Expression Level Scale		None Extremely low Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Developmental Stage		Expression Level
embryo 00-02hr
embryo 02-04hr
embryo 04-06hr
embryo 06-08hr
embryo 08-10hr
embryo 10-12hr
embryo 12-14hr
embryo 14-16hr
embryo 16-18hr
embryo 18-20hr
embryo 20-22hr
embryo 22-24hr
larva L1
larva L2
larva L3 12hr old
larva L3 puffstage 1-2
larva L3 puffstage 3-6
larva L3 puffstage 7-9
white prepupae new
white prepupae 12hr
white prepupae 24hr
pupae 2d postWPP
pupae 3d postWPP
pupae 4d postWPP
adult male 01day
adult male 05day
adult male 30day
adult female 01day
adult female 05day
adult female 30day

FlyAtlas Anatomical Expression Data for FBgn0036018

	Styles
	Linear
	Logarithmic
	Heatmap
	Back-to-back
	Scales
	max expr for FBgn0036018
	Moderate expression bin max
	High level expression bin max
	Very high expression bin max

Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: larval central nervous system, adult female reproductive system, adult male accessory gland.
[download data (TSV)]

Guide to FlyAtlas expression level colors
	No expression (0 - 9.999)
	Low expression (10 - 99.999)
	Moderate expression (100 - 499.999)
	High level expression (500 - 999.999)
	Very high expression (1000 - 25000)

Linear, scaled to maximum FBgn0036018 expression level
Tissue		Expression Level
Larval Central Nervous System		114.625
Larval Midgut		43.5
Larval Hindgut		62.3
Larval Malpighian Tubules		38.9
Larval Fat Body		30.8
Larval Salivary Gland		80.5
Larval Trachea		82.725
Larval Carcass		73.85
Adult Head		41.5
Adult Eye		38.425
Adult Brain		42.2
Adult Thoracic-Abdominal Ganglion		55.4
Adult Crop		75.2
Adult Midgut		44.6
Adult Hindgut		40.4
Adult Malpighian Tubules		51.5
Adult Fat Body		68.5
Adult Salivary Gland		99
Adult Heart		39.75
Adult VirginFemale Spermatheca		68
Adult InseminatedFemale Spermatheca		100.2
Adult Ovary		177.6
Adult Testis		40.3
Adult Male Accessory Gland		118.7
Adult Carcass		60.6
Expression Level Scale		None Low Moderate

Linear, scaled to Moderate expression
Tissue		Expression Level
Larval Central Nervous System		114.625
Larval Midgut		43.5
Larval Hindgut		62.3
Larval Malpighian Tubules		38.9
Larval Fat Body		30.8
Larval Salivary Gland		80.5
Larval Trachea		82.725
Larval Carcass		73.85
Adult Head		41.5
Adult Eye		38.425
Adult Brain		42.2
Adult Thoracic-Abdominal Ganglion		55.4
Adult Crop		75.2
Adult Midgut		44.6
Adult Hindgut		40.4
Adult Malpighian Tubules		51.5
Adult Fat Body		68.5
Adult Salivary Gland		99
Adult Heart		39.75
Adult VirginFemale Spermatheca		68
Adult InseminatedFemale Spermatheca		100.2
Adult Ovary		177.6
Adult Testis		40.3
Adult Male Accessory Gland		118.7
Adult Carcass		60.6
Expression Level Scale		None Low Moderate High

Linear, scaled to High level expression
Tissue		Expression Level
Larval Central Nervous System		114.625
Larval Midgut		43.5
Larval Hindgut		62.3
Larval Malpighian Tubules		38.9
Larval Fat Body		30.8
Larval Salivary Gland		80.5
Larval Trachea		82.725
Larval Carcass		73.85
Adult Head		41.5
Adult Eye		38.425
Adult Brain		42.2
Adult Thoracic-Abdominal Ganglion		55.4
Adult Crop		75.2
Adult Midgut		44.6
Adult Hindgut		40.4
Adult Malpighian Tubules		51.5
Adult Fat Body		68.5
Adult Salivary Gland		99
Adult Heart		39.75
Adult VirginFemale Spermatheca		68
Adult InseminatedFemale Spermatheca		100.2
Adult Ovary		177.6
Adult Testis		40.3
Adult Male Accessory Gland		118.7
Adult Carcass		60.6
Expression Level Scale		None Low Moderate High Very high

Linear, scaled to Very high expression
Tissue		Expression Level
Larval Central Nervous System		114.625
Larval Midgut		43.5
Larval Hindgut		62.3
Larval Malpighian Tubules		38.9
Larval Fat Body		30.8
Larval Salivary Gland		80.5
Larval Trachea		82.725
Larval Carcass		73.85
Adult Head		41.5
Adult Eye		38.425
Adult Brain		42.2
Adult Thoracic-Abdominal Ganglion		55.4
Adult Crop		75.2
Adult Midgut		44.6
Adult Hindgut		40.4
Adult Malpighian Tubules		51.5
Adult Fat Body		68.5
Adult Salivary Gland		99
Adult Heart		39.75
Adult VirginFemale Spermatheca		68
Adult InseminatedFemale Spermatheca		100.2
Adult Ovary		177.6
Adult Testis		40.3
Adult Male Accessory Gland		118.7
Adult Carcass		60.6
Expression Level Scale		None Low Moderate High Very high

log, scaled to maximum FBgn0036018 expression level
Tissue		Expression Level
Larval Central Nervous System		114.625
Larval Midgut		43.5
Larval Hindgut		62.3
Larval Malpighian Tubules		38.9
Larval Fat Body		30.8
Larval Salivary Gland		80.5
Larval Trachea		82.725
Larval Carcass		73.85
Adult Head		41.5
Adult Eye		38.425
Adult Brain		42.2
Adult Thoracic-Abdominal Ganglion		55.4
Adult Crop		75.2
Adult Midgut		44.6
Adult Hindgut		40.4
Adult Malpighian Tubules		51.5
Adult Fat Body		68.5
Adult Salivary Gland		99
Adult Heart		39.75
Adult VirginFemale Spermatheca		68
Adult InseminatedFemale Spermatheca		100.2
Adult Ovary		177.6
Adult Testis		40.3
Adult Male Accessory Gland		118.7
Adult Carcass		60.6
Expression Level Scale		None Low Moderate

log, scaled to Moderate expression
Tissue		Expression Level
Larval Central Nervous System		114.625
Larval Midgut		43.5
Larval Hindgut		62.3
Larval Malpighian Tubules		38.9
Larval Fat Body		30.8
Larval Salivary Gland		80.5
Larval Trachea		82.725
Larval Carcass		73.85
Adult Head		41.5
Adult Eye		38.425
Adult Brain		42.2
Adult Thoracic-Abdominal Ganglion		55.4
Adult Crop		75.2
Adult Midgut		44.6
Adult Hindgut		40.4
Adult Malpighian Tubules		51.5
Adult Fat Body		68.5
Adult Salivary Gland		99
Adult Heart		39.75
Adult VirginFemale Spermatheca		68
Adult InseminatedFemale Spermatheca		100.2
Adult Ovary		177.6
Adult Testis		40.3
Adult Male Accessory Gland		118.7
Adult Carcass		60.6
Expression Level Scale		None Low Moderate High

log, scaled to High level expression
Tissue		Expression Level
Larval Central Nervous System		114.625
Larval Midgut		43.5
Larval Hindgut		62.3
Larval Malpighian Tubules		38.9
Larval Fat Body		30.8
Larval Salivary Gland		80.5
Larval Trachea		82.725
Larval Carcass		73.85
Adult Head		41.5
Adult Eye		38.425
Adult Brain		42.2
Adult Thoracic-Abdominal Ganglion		55.4
Adult Crop		75.2
Adult Midgut		44.6
Adult Hindgut		40.4
Adult Malpighian Tubules		51.5
Adult Fat Body		68.5
Adult Salivary Gland		99
Adult Heart		39.75
Adult VirginFemale Spermatheca		68
Adult InseminatedFemale Spermatheca		100.2
Adult Ovary		177.6
Adult Testis		40.3
Adult Male Accessory Gland		118.7
Adult Carcass		60.6
Expression Level Scale		None Low Moderate High Very high

log, scaled to Very high expression
Tissue		Expression Level
Larval Central Nervous System		114.625
Larval Midgut		43.5
Larval Hindgut		62.3
Larval Malpighian Tubules		38.9
Larval Fat Body		30.8
Larval Salivary Gland		80.5
Larval Trachea		82.725
Larval Carcass		73.85
Adult Head		41.5
Adult Eye		38.425
Adult Brain		42.2
Adult Thoracic-Abdominal Ganglion		55.4
Adult Crop		75.2
Adult Midgut		44.6
Adult Hindgut		40.4
Adult Malpighian Tubules		51.5
Adult Fat Body		68.5
Adult Salivary Gland		99
Adult Heart		39.75
Adult VirginFemale Spermatheca		68
Adult InseminatedFemale Spermatheca		100.2
Adult Ovary		177.6
Adult Testis		40.3
Adult Male Accessory Gland		118.7
Adult Carcass		60.6
Expression Level Scale		None Low Moderate High Very high

Heatmap
Tissue		Expression Level
Larval Central Nervous System
Larval Midgut
Larval Hindgut
Larval Malpighian Tubules
Larval Fat Body
Larval Salivary Gland
Larval Trachea
Larval Carcass
Adult Head
Adult Eye
Adult Brain
Adult Thoracic-Abdominal Ganglion
Adult Crop
Adult Midgut
Adult Hindgut
Adult Malpighian Tubules
Adult Fat Body
Adult Salivary Gland
Adult Heart
Adult VirginFemale Spermatheca
Adult InseminatedFemale Spermatheca
Adult Ovary
Adult Testis
Adult Male Accessory Gland
Adult Carcass

FlyAtlas Organ/Tissue Expression, larval vs. adult
Larval Expression Level	Tissue	Adult Expression Level
NA	Head	41.5
NA	Eye	38.425
NA	Brain	42.2
114.625	Central Nervous System	NA
NA	Thoracic-Abdominal Ganglion	55.4
NA	Crop	75.2
43.5	Midgut	44.6
62.3	Hindgut	40.4
38.9	Malpighian Tubules	51.5
30.8	Fat Body	68.5
80.5	Salivary Gland	99
NA	Heart	39.75
82.725	Trachea	NA
NA	VirginFemale Spermatheca	68
NA	InseminatedFemale Spermatheca	100.2
NA	Ovary	177.6
NA	Testis	40.3
NA	Male Accessory Gland	118.7
73.85	Carcass	60.6

modENCODE Temporal Expression Data (Graveley et al., 2011)
FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)

Expression Clusters

A cluster of genes with similar mRNA expression dynamics across development.

(The modENCODE Consortium, 2010)

mE2_34_mRNA_expression_cluster_08

External Data & Images

Linkouts

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

•

FBgn0036018

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

•

CG3335-RA

Alleles & Phenotypes

Summary of Allele Phenotypes

Phenotype manifest in

Allele

Classical Alleles ( 1 )

For All Classical Alleles Show

Allele of CG3335	Class	Mutagen	Stocks	Known lesion
CG3335^c05958		piggyBac transposase	2	--

Alleles Carried on Transgenic Constructs ( 1 )

For All Alleles Carried on Transgenic Constructs Show

Allele of CG3335	Class	Mutagen	Stocks	Known lesion
CG3335^GD10624		in vitro construct - RNAi in vitro construct - regulatory fusion	0	Yes

Aneuploid Aberrations

Disrupted in

Df(3L)Exel6114

(Ryder, 2004.4.26)

Transgenic Constructs & Insertions

Transgenic Constructs

Type of construct

Name

Expression data

UAS construct

P{GD10624}

Insertions

Type of insertions

Name

Expression data

miscellaneous insertions

PBac{PB}CG3335^c05958

Gene Ontology: Function, Process & Cellular Component ( 4 unique terms )

Terms Based on Experimental Evidence ( 0 terms )

Terms Based on Predictions or Assertions ( 4 terms )

Molecular Function

CV term

Evidence

References

helicase activity

inferred from sequence or structural similarity

(Lasko, 2000)

mRNA binding

inferred from sequence or structural similarity

(Lasko, 2000)

nucleic acid binding

inferred from electronic annotation with InterPro:IPR000504

(FlyBase Curators et al., 2004-)

nucleotide binding

inferred from electronic annotation with InterPro:IPR012677

(FlyBase Curators et al., 2004-)

Biological Process ( 0 terms)

Cellular Component ( 0 terms)

Sequence Ontology: Class of Gene

nuclear_gene

protein_coding_gene

Interactions & Pathways

Summary of Physical Interactions

Protein-protein

Interacting group

Assay

References

Summary of Genetic Interactions

Interacts with

Please look at the allele data for full details of the genetic interactions

CG3335 allele

Gene

References

External Data

Linkouts

BioGRID - A database of protein and genetic interactions

•

64510

DroID - A comprehensive database of gene and protein interactions.

•

FBgn0036018

InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets.

•

39119

Orthologs

Genome-wide drosophilid orthologs

Dana\GF22183

Dere\GG15393

Dgri\GH12037

Dmoj\GI16192

Dper\GL16640

Dpse\GA22839

Dsec\GM25167

Dsim\GD14198

Dvir\GJ16680

Dwil\GK16446

Dyak\GE20857

Curated drosophilid orthologs

Linkouts

InParanoid A subset of ortholog calls from InParanoid.

•

AAEL004075-PA
Aedes aegypti (mosquito)
AGAP005249-PA
Anopheles gambiae (mosquito)
XP_624611.2
Apis mellifera (honey bee)
XP_001949363.1
Acyrthosiphon pisum (pea aphid)
At4g19610.1
Arabidopsis thaliana (wall cress)
8977
Batrachochytrium dendrobatidis (chytrid fungus)
86976
Branchiostoma floridae (lancelet)
XP_001902435.1
Brugia malayi (roundworm nematode)
CAL0000019
Candida albicans (a form of yeast)
CN00502
Caenorhabditis brenneri (small nematode)
CBP00919
Caenorhabditis briggsae (nematode)
CE18963
Caenorhabditis elegans (worm)
ENSCAFP00000013469
Canis familiaris (dog)
CAGL0B04169g
Candida glabrata (haploid yeast)
Chro.60541
Cryptosporidium hominis (obligate parasite)
CMO246C
Cyanidioschyzon merolae (red alga)
cn03112
Cryptococcus neoformans (yeast-like fungus)
cgd6_4710
Cryptosporidium parvum (protozoan parasite)
CPIJ009685
Culex pipens (mosquito)
ENSCPOP00000015079
Cavia porcellus (guinea pig)
RP34027
Caenorhabditis remanei (nematode)
RP45829
Caenorhabditis remanei (nematode)
225018
Capitella spl (polychaete worm)
DDB0233347
Dictyostelium discoideum (amoeba)
DEHA2D17358g
Debaryomyces Hansenii (yeast)
306569
Daphnia pulex (daphnia)
ENSDARP00000062458
Danio rerio (zebra fish)
ENSECAP00000021297
Equus caballus (horse)
XP_655058
Entamoeba histolytica (anaerobic protozoan)
ENSGACP00000012505
Gymnopilus aculeatus (mushroom)
ENSGALP00000037196
Gallus gallus (chicken)
GL50803_3993
Giardia lamblia (flagellated protozoan)
99246
Hypsipyla robusta (cedar shoot borer)
ENSP00000261741
Homo sapiens (human)
KLLA0D14949g
Kluyveromyces lactis (yeast)
190610
Lottia gigantea (owl limpet)
LmjF10.0700
Leishmania major (virus)
22903
Monocosta brevicollis (choanoflagellate)
ENSMODP00000004397
Monodelphis domestica (gray opossum)
ENSMMUP00000013760
Macaca mulatta (rhesus monkey)
ENSMUSP00000031590
Mus musculus (house mouse)
86616
Nematostella vectensis (starlet anemone)
XP_001605134.1
Nasonia vitripennis (wasp)
ENSORLP00000010136
Oryzias latipes (japanese killifish)
LOC_Os04g52200.1
Oryza sativa (asian rice)
16909
Ostreococcus tauri (green alga)
PFL0830w
Plasmodium falciparum (protozoal parasite)
PHUM000973-PA
Pediculus humanus (human body louse)
207810
Physcomitrella patens (moss)
ENSPPYP00000005695
Pongo pygmaeus (orangutan)
74707
Phytophthora ramorum (sudden oak death pathogen)
129427
Phytophthora sojae (root rot pathogen)
413036
Populus trichocarpa (black cottonwood)
ENSPTRP00000009322
Pan troglodytes (chimpanzee)
PVX_123535
Plasmodium vivax (protozoal parasite)
ENSRNOP00000001891
Rattus norvegicus (norway rat)
5006906
Sorghum bicolor (sorghum)
YPR112C
Saccharomyces cerevisiae (budding yeast)
Smp_141240
Schistosoma mansoni (trematode parasite)
SPBP22H7.02c
Schizosaccharomyces pombe (fission yeast)
TA08240
Theileria annulata (apicomplexan parasite)
XP_001807432.1
Tribolium castaneum (red flour beetle)
Tc00.1047053503897.90
Trypanosoma cruzi (parasitic trypanosome)
Tc00.1047053509561.110
Trypanosoma cruzi (parasitic trypanosome)
ENSTNIP00000015150
Tetraodon nigroviridis (green spotted pufferfish)
TP04_0400
Theileria parva (parasitic protozoan)
268689
Thalassiosira pseudonana (marine diatom)
ENSTRUP00000041001
Takifugu rubripes (pufferfish Takifugu)
3714.m00005
Tetrahymena thermophila (ciliate protozoa)
ENSXETP00000038351
Xenopus tropicalis (frog)
YALI0B12276g
Yarrowia lipolytica (nonconventional yeast)

OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs.

Stocks & Reagents

Stocks Listed in FlyBase ( 2 )

Bloomington

17737

w¹¹¹⁸; PBac{PB}CG3335^c05958/TM6B, Tb¹

Harvard

PBac{PB}CG3335^c05958

Genomic Clones ( 2 )

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones ( 7 )

Please Note

This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA Clones, Fully Sequenced

BDGP DGC clones

SD14970

Other clones

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi & Array Information

Linkouts

DRSC - Results from RNAi screens.

•

FBgn0036018

GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents

•

39119

Antibody Information

Other Information

Discoverer

Etymology

Identification

Relationship to Other Genes

Source for database identity of

Source for database merge of

Additional comments

Other Comments

External Crossreferences & Linkouts

Sequence Crossreferences

RefSeq (Transcripts)

•

NM_140080

RefSeq (Proteins)

•

NP_648337

DDBJ / EMBL / GenBank

•

Entrez Gene - A searchable database of RefSeq genes.

•

39119

UniProtKB/TrEMBL

•

Other Crossreferences

InterPro domains - A database of protein families, domains, and functional sites

•

RNA recognition motif domain (IPR000504)

Nucleotide-binding, alpha-beta plait (IPR012677)

Linkouts

BioGRID - A database of protein and genetic interactions

•

64510

DroID - A comprehensive database of gene and protein interactions.

•

FBgn0036018

DRSC - Results from RNAi screens.

•

FBgn0036018

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

•

FBgn0036018

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

•

CG3335-RA

FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans

•

FBgn0036018

GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents

•

39119

InParanoid A subset of ortholog calls from InParanoid.

•

AAEL004075-PA
Aedes aegypti (mosquito)
AGAP005249-PA
Anopheles gambiae (mosquito)
XP_624611.2
Apis mellifera (honey bee)
XP_001949363.1
Acyrthosiphon pisum (pea aphid)
At4g19610.1
Arabidopsis thaliana (wall cress)
8977
Batrachochytrium dendrobatidis (chytrid fungus)
86976
Branchiostoma floridae (lancelet)
XP_001902435.1
Brugia malayi (roundworm nematode)
CAL0000019
Candida albicans (a form of yeast)
CN00502
Caenorhabditis brenneri (small nematode)
CBP00919
Caenorhabditis briggsae (nematode)
CE18963
Caenorhabditis elegans (worm)
ENSCAFP00000013469
Canis familiaris (dog)
CAGL0B04169g
Candida glabrata (haploid yeast)
Chro.60541
Cryptosporidium hominis (obligate parasite)
CMO246C
Cyanidioschyzon merolae (red alga)
cn03112
Cryptococcus neoformans (yeast-like fungus)
cgd6_4710
Cryptosporidium parvum (protozoan parasite)
CPIJ009685
Culex pipens (mosquito)
ENSCPOP00000015079
Cavia porcellus (guinea pig)
RP34027
Caenorhabditis remanei (nematode)
RP45829
Caenorhabditis remanei (nematode)
225018
Capitella spl (polychaete worm)
DDB0233347
Dictyostelium discoideum (amoeba)
DEHA2D17358g
Debaryomyces Hansenii (yeast)
306569
Daphnia pulex (daphnia)
ENSDARP00000062458
Danio rerio (zebra fish)
ENSECAP00000021297
Equus caballus (horse)
XP_655058
Entamoeba histolytica (anaerobic protozoan)
ENSGACP00000012505
Gymnopilus aculeatus (mushroom)
ENSGALP00000037196
Gallus gallus (chicken)
GL50803_3993
Giardia lamblia (flagellated protozoan)
99246
Hypsipyla robusta (cedar shoot borer)
ENSP00000261741
Homo sapiens (human)
KLLA0D14949g
Kluyveromyces lactis (yeast)
190610
Lottia gigantea (owl limpet)
LmjF10.0700
Leishmania major (virus)
22903
Monocosta brevicollis (choanoflagellate)
ENSMODP00000004397
Monodelphis domestica (gray opossum)
ENSMMUP00000013760
Macaca mulatta (rhesus monkey)
ENSMUSP00000031590
Mus musculus (house mouse)
86616
Nematostella vectensis (starlet anemone)
XP_001605134.1
Nasonia vitripennis (wasp)
ENSORLP00000010136
Oryzias latipes (japanese killifish)
LOC_Os04g52200.1
Oryza sativa (asian rice)
16909
Ostreococcus tauri (green alga)
PFL0830w
Plasmodium falciparum (protozoal parasite)
PHUM000973-PA
Pediculus humanus (human body louse)
207810
Physcomitrella patens (moss)
ENSPPYP00000005695
Pongo pygmaeus (orangutan)
74707
Phytophthora ramorum (sudden oak death pathogen)
129427
Phytophthora sojae (root rot pathogen)
413036
Populus trichocarpa (black cottonwood)
ENSPTRP00000009322
Pan troglodytes (chimpanzee)
PVX_123535
Plasmodium vivax (protozoal parasite)
ENSRNOP00000001891
Rattus norvegicus (norway rat)
5006906
Sorghum bicolor (sorghum)
YPR112C
Saccharomyces cerevisiae (budding yeast)
Smp_141240
Schistosoma mansoni (trematode parasite)
SPBP22H7.02c
Schizosaccharomyces pombe (fission yeast)
TA08240
Theileria annulata (apicomplexan parasite)
XP_001807432.1
Tribolium castaneum (red flour beetle)
Tc00.1047053503897.90
Trypanosoma cruzi (parasitic trypanosome)
Tc00.1047053509561.110
Trypanosoma cruzi (parasitic trypanosome)
ENSTNIP00000015150
Tetraodon nigroviridis (green spotted pufferfish)
TP04_0400
Theileria parva (parasitic protozoan)
268689
Thalassiosira pseudonana (marine diatom)
ENSTRUP00000041001
Takifugu rubripes (pufferfish Takifugu)
3714.m00005
Tetrahymena thermophila (ciliate protozoa)
ENSXETP00000038351
Xenopus tropicalis (frog)
YALI0B12276g
Yarrowia lipolytica (nonconventional yeast)

InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets.

•

39119

modMine - Data generated by the modENCODE project.

•

FBgn0036018

OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs.

Synonyms & Secondary IDs ( 4 )

Reported As

Symbol Synonym

cg3335

(Lasko, 2000)

CG3335

(Ayroles et al., 2009, Stone and Ayroles, 2009, Wasbrough et al., 2010)

Dm-RBD-1

(Bjork et al., 2002)

Q9VT19

(Bjork et al., 2002)

Name Synonym

Secondary FlyBase IDs

References ( 16 )

Research paper

Ayroles et al., 2009, Nature Genetics 41(3): 299--307: Systems genetics of complex traits in Drosophila melanogaster. [FBrf0206705]
Stone and Ayroles, 2009, PLoS Genet. 5(5): e1000479: Modulated modularity clustering as an exploratory tool for functional genomic inference. [FBrf0207986]
Bjork et al., 2002, Molec. Biol. Cell 13(10): 3683--3695: A novel conserved RNA-binding domain protein, RBD-1, is essential for ribosome biogenesis. [FBrf0159864]
Lasko, 2000, J. Cell Biol. 150(2): F51--F56: The Drosophila melanogaster genome: translation factors and RNA binding proteins. [FBrf0129923]

Supplementary material

The modENCODE Consortium, 2010, Science 330(6012):: DataS14: Gene co-expression clusters. [FBrf0213979]
Wasbrough et al., 2010, J. Proteomics 73(11):: Supplemental Table 1. Mass spectrometry data. [FBrf0213252]
Dietzl et al., 2007, Nature 448(7150):: Supplementary Table 1. [FBrf0202579]
Giot et al., 2003, Science 302(5651):: Tables S1 to S7. [FBrf0166452]

Personal communication to FlyBase

Bloomington Drosophila Stock Center, 2004.11.6, Exelixis insertion alleles that are not in FlyBase.: Exelixis insertion alleles that are not in FlyBase. [FBrf0179797]
FlyBase Curators et al., 2004-, Gene Ontology annotation in FlyBase through association of InterPro records with GO terms.: Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. [FBrf0174215]
Ryder, 2004.4.26, Exelixis CG deletion data.: Exelixis CG deletion data. [FBrf0184335]

FlyBase analysis

FlyBase, 1992-, FlyBase curation: FlyBase curation. [FBrf0105495]

Computer file

BDGP Project Members, 2000-, Berkeley Drosophila Genome Project.: Berkeley Drosophila Genome Project. [FBrf0125078]

Automatic genome annotation

FamiliarityBreedsContempt, 1999.11, [Annotations performed at the Celera Jamboreee.]: [Annotations performed at the Celera Jamboreee.] [FBrf0126705]

Curated genome annotation

Lasko, 1999.11, [Annotations performed at the Celera Jamboreee.]: [Annotations performed at the Celera Jamboreee.] [FBrf0126679]