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Gene Dmel\CG8336

General Information
Symbol	Dmel\CG8336	Species	D. melanogaster
Name		Annotation symbol	CG8336
Feature type	protein_coding_gene	FlyBase ID	FBgn0036020
Gene Model Status	Current	Stock availability	3 publicly available
Genomic Location
Chromosome (arm)	3L	Recombination map
Cytogenetic map	67C2-67C3	Sequence location	3L:9,621,776..9,624,895 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG8336 (FBgn0036020). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function: peptidyl-prolyl cis-trans isomerase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: protein folding. 4 alleles are reported. No phenotypic data is available. It has 4 annotated transcripts and 4 annotated polypeptides. Protein features are: Cyclophilin-like peptidyl-prolyl cis-trans isomerase domain; Tetratricopeptide TPR2; Tetratricopeptide repeat; Tetratricopeptide repeat-containing domain; Tetratricopeptide-like helical. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed within 00-12 and 18-24 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in stages of adults of both sexes. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: larval/adult central nervous system, adult crop, larval/adult hindgut, larval/adult Malpighian tubules, larval fat body, larval/adult salivary gland, larval trachea, adult ovary, adult testis. Comments on Affy2 ProbeSet: ProbeSet 1635293_s_at completely aligns to an exonic region common to each of the 3 FlyBase-annotated transcript isoforms of CG8336. Gene sequence location is 3L:9621776..9624895.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 67C2-67C3   Limits computationally determined from genome sequence between P{EP}Hsp26EP3336&P{EP}Hsp26EP3315 and P{PZ}fry02240
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG8336 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.46
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG8336-RA FBtr0076385  NM_140081   1500   383 CG8336-RB FBtr0076384  NM_168354   1555   383 CG8336-RC FBtr0076386  NM_168355   1445   383 CG8336-RD FBtr0333855  NM_001274707   1395   383
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG8336-PA   FBpp0076114   43.1   383   7.77     NP_648338   AAN11947 CG8336-PB   FBpp0076113   43.1   383   7.77     NP_729517   AAN11948 CG8336-PC   FBpp0076115   43.1   383   7.77     NP_729518   AAF50235 CG8336-PD   FBpp0305988   43.1   383   7.77     NP_001261636   AGB94331
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Tetratricopeptide TPR2 (IPR013105) Cyclophilin-like peptidyl-prolyl cis-trans isomerase domain (IPR002130) Tetratricopeptide-like helical (IPR011990) Tetratricopeptide repeat-containing domain (IPR013026) Tetratricopeptide repeat (IPR019734)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA201683   AA392417   AE014296 AAF50235   AE014296 AAN11947   AE014296 AAN11948   AE014296 AGB94331   AI107102   AI135221   AI389222   AI402046   AI946971   AY058303 AAL13532   BF495102   BF498690   BF501027   BF503525   BF505007   BF506739   BI366355   BI481815   BI482624   CO270331   CO328193   CO334054   EC068426   EC197315   EC223988   EC254191   GH955376   GH958635   GH962188   GH963641   GH968740   GH974415   GH977013   GH979844   GH983279   GH983474   GH983947
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9VT21
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
in situ Stage Tissue/Position (including subcellular localization) Reference embryonic stage 1 -- 3   organism   (Fisher et al., 2012) Comment:maternally deposited embryonic stage 4 -- 6   organism | faint & ubiquitous   (Fisher et al., 2012) embryonic stage 7 -- 8   organism | faint & ubiquitous   (Fisher et al., 2012) embryonic stage 9 -- 10   organism | faint & ubiquitous   (Fisher et al., 2012)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: larval/adult central nervous system, adult crop, larval/adult hindgut, larval/adult Malpighian tubules, larval fat body, larval/adult salivary gland, larval trachea, adult ovary, adult testis. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    128.225 Larval Midgut    58.7 Larval Hindgut    110.9 Larval Malpighian Tubules    168.8 Larval Fat Body    103.1 Larval Salivary Gland    142.6 Larval Trachea    101.125 Larval Carcass    75.625 Adult Head    58.9 Adult Eye    93.4 Adult Brain    103 Adult Thoracic-Abdominal Ganglion    93.7 Adult Crop    179.9 Adult Midgut    77.6 Adult Hindgut    117.9 Adult Malpighian Tubules    173.9 Adult Fat Body    85.3 Adult Salivary Gland    146.1 Adult Heart    74.275 Adult VirginFemale Spermatheca    50.1 Adult InseminatedFemale Spermatheca    39.9 Adult Ovary    171 Adult Testis    387.6 Adult Male Accessory Gland    96.5 Adult Carcass    77.3 Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    128.225 Larval Midgut    58.7 Larval Hindgut    110.9 Larval Malpighian Tubules    168.8 Larval Fat Body    103.1 Larval Salivary Gland    142.6 Larval Trachea    101.125 Larval Carcass    75.625 Adult Head    58.9 Adult Eye    93.4 Adult Brain    103 Adult Thoracic-Abdominal Ganglion    93.7 Adult Crop    179.9 Adult Midgut    77.6 Adult Hindgut    117.9 Adult Malpighian Tubules    173.9 Adult Fat Body    85.3 Adult Salivary Gland    146.1 Adult Heart    74.275 Adult VirginFemale Spermatheca    50.1 Adult InseminatedFemale Spermatheca    39.9 Adult Ovary    171 Adult Testis    387.6 Adult Male Accessory Gland    96.5 Adult Carcass    77.3 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    128.225 Larval Midgut    58.7 Larval Hindgut    110.9 Larval Malpighian Tubules    168.8 Larval Fat Body    103.1 Larval Salivary Gland    142.6 Larval Trachea    101.125 Larval Carcass    75.625 Adult Head    58.9 Adult Eye    93.4 Adult Brain    103 Adult Thoracic-Abdominal Ganglion    93.7 Adult Crop    179.9 Adult Midgut    77.6 Adult Hindgut    117.9 Adult Malpighian Tubules    173.9 Adult Fat Body    85.3 Adult Salivary Gland    146.1 Adult Heart    74.275 Adult VirginFemale Spermatheca    50.1 Adult InseminatedFemale Spermatheca    39.9 Adult Ovary    171 Adult Testis    387.6 Adult Male Accessory Gland    96.5 Adult Carcass    77.3 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    128.225 Larval Midgut    58.7 Larval Hindgut    110.9 Larval Malpighian Tubules    168.8 Larval Fat Body    103.1 Larval Salivary Gland    142.6 Larval Trachea    101.125 Larval Carcass    75.625 Adult Head    58.9 Adult Eye    93.4 Adult Brain    103 Adult Thoracic-Abdominal Ganglion    93.7 Adult Crop    179.9 Adult Midgut    77.6 Adult Hindgut    117.9 Adult Malpighian Tubules    173.9 Adult Fat Body    85.3 Adult Salivary Gland    146.1 Adult Heart    74.275 Adult VirginFemale Spermatheca    50.1 Adult InseminatedFemale Spermatheca    39.9 Adult Ovary    171 Adult Testis    387.6 Adult Male Accessory Gland    96.5 Adult Carcass    77.3 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    128.225 Larval Midgut    58.7 Larval Hindgut    110.9 Larval Malpighian Tubules    168.8 Larval Fat Body    103.1 Larval Salivary Gland    142.6 Larval Trachea    101.125 Larval Carcass    75.625 Adult Head    58.9 Adult Eye    93.4 Adult Brain    103 Adult Thoracic-Abdominal Ganglion    93.7 Adult Crop    179.9 Adult Midgut    77.6 Adult Hindgut    117.9 Adult Malpighian Tubules    173.9 Adult Fat Body    85.3 Adult Salivary Gland    146.1 Adult Heart    74.275 Adult VirginFemale Spermatheca    50.1 Adult InseminatedFemale Spermatheca    39.9 Adult Ovary    171 Adult Testis    387.6 Adult Male Accessory Gland    96.5 Adult Carcass    77.3 Expression Level Scale  None   Low   Moderate   High  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    128.225 Larval Midgut    58.7 Larval Hindgut    110.9 Larval Malpighian Tubules    168.8 Larval Fat Body    103.1 Larval Salivary Gland    142.6 Larval Trachea    101.125 Larval Carcass    75.625 Adult Head    58.9 Adult Eye    93.4 Adult Brain    103 Adult Thoracic-Abdominal Ganglion    93.7 Adult Crop    179.9 Adult Midgut    77.6 Adult Hindgut    117.9 Adult Malpighian Tubules    173.9 Adult Fat Body    85.3 Adult Salivary Gland    146.1 Adult Heart    74.275 Adult VirginFemale Spermatheca    50.1 Adult InseminatedFemale Spermatheca    39.9 Adult Ovary    171 Adult Testis    387.6 Adult Male Accessory Gland    96.5 Adult Carcass    77.3 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    128.225 Larval Midgut    58.7 Larval Hindgut    110.9 Larval Malpighian Tubules    168.8 Larval Fat Body    103.1 Larval Salivary Gland    142.6 Larval Trachea    101.125 Larval Carcass    75.625 Adult Head    58.9 Adult Eye    93.4 Adult Brain    103 Adult Thoracic-Abdominal Ganglion    93.7 Adult Crop    179.9 Adult Midgut    77.6 Adult Hindgut    117.9 Adult Malpighian Tubules    173.9 Adult Fat Body    85.3 Adult Salivary Gland    146.1 Adult Heart    74.275 Adult VirginFemale Spermatheca    50.1 Adult InseminatedFemale Spermatheca    39.9 Adult Ovary    171 Adult Testis    387.6 Adult Male Accessory Gland    96.5 Adult Carcass    77.3 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    128.225 Larval Midgut    58.7 Larval Hindgut    110.9 Larval Malpighian Tubules    168.8 Larval Fat Body    103.1 Larval Salivary Gland    142.6 Larval Trachea    101.125 Larval Carcass    75.625 Adult Head    58.9 Adult Eye    93.4 Adult Brain    103 Adult Thoracic-Abdominal Ganglion    93.7 Adult Crop    179.9 Adult Midgut    77.6 Adult Hindgut    117.9 Adult Malpighian Tubules    173.9 Adult Fat Body    85.3 Adult Salivary Gland    146.1 Adult Heart    74.275 Adult VirginFemale Spermatheca    50.1 Adult InseminatedFemale Spermatheca    39.9 Adult Ovary    171 Adult Testis    387.6 Adult Male Accessory Gland    96.5 Adult Carcass    77.3 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    58.9   NA  Eye    93.4   NA  Brain    103   128.225  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    93.7   NA  Crop    179.9   58.7  Midgut    77.6   110.9  Hindgut    117.9   168.8  Malpighian Tubules    173.9   103.1  Fat Body    85.3   142.6  Salivary Gland    146.1   NA  Heart    74.275   101.125  Trachea    NA   NA  VirginFemale Spermatheca    50.1   NA  InseminatedFemale Spermatheca    39.9   NA  Ovary    171   NA  Testis    387.6   NA  Male Accessory Gland    96.5   75.625  Carcass    77.3 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    82 central nervous system, larvae L3    25 central nervous system, pupae P8    18 head, virgin 1-day female    9 head, virgin 4-day female    17 head, virgin 20-day female    10 head, mated 1-day female    13 head, mated 4-day female    11 head, mated 20-day female    11 head, mated 1-day male    18 head, mated 4-day male    18 head, mated 20-day male    23 salivary gland, larvae L3 wandering    11 salivary gland, white prepupae    21 digestive system, larvae L3 wandering    33 digestive system, 1-day adult    16 digestive system, 4-day adult    17 digestive system, 20-day adult    16 fat body, larvae L3 wandering    9 fat body, white prepupae    25 fat body, pupae P8    76 carcass, larvae L3 wandering    21 carcass, 1-day adult    12 carcass, 4-day adult    14 carcass, 20-day adult    17 ovary, virgin 4-day female    44 ovary, mated 4-day female    44 testis, mated 4-day male    121 accessory gland, mated 4-day male    23 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (82) central nervous system, larvae L3    25 central nervous system, pupae P8    18 head, virgin 1-day female    9 head, virgin 4-day female    17 head, virgin 20-day female    10 head, mated 1-day female    13 head, mated 4-day female    11 head, mated 20-day female    11 head, mated 1-day male    18 head, mated 4-day male    18 head, mated 20-day male    23 salivary gland, larvae L3 wandering    11 salivary gland, white prepupae    21 digestive system, larvae L3 wandering  (33) digestive system, 1-day adult    16 digestive system, 4-day adult    17 digestive system, 20-day adult    16 fat body, larvae L3 wandering    9 fat body, white prepupae    25 fat body, pupae P8  (76) carcass, larvae L3 wandering    21 carcass, 1-day adult    12 carcass, 4-day adult    14 carcass, 20-day adult    17 ovary, virgin 4-day female  (44) ovary, mated 4-day female  (44) testis, mated 4-day male  (121) accessory gland, mated 4-day male    23 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    82 central nervous system, larvae L3    25 central nervous system, pupae P8    18 head, virgin 1-day female    9 head, virgin 4-day female    17 head, virgin 20-day female    10 head, mated 1-day female    13 head, mated 4-day female    11 head, mated 20-day female    11 head, mated 1-day male    18 head, mated 4-day male    18 head, mated 20-day male    23 salivary gland, larvae L3 wandering    11 salivary gland, white prepupae    21 digestive system, larvae L3 wandering    33 digestive system, 1-day adult    16 digestive system, 4-day adult    17 digestive system, 20-day adult    16 fat body, larvae L3 wandering    9 fat body, white prepupae    25 fat body, pupae P8    76 carcass, larvae L3 wandering    21 carcass, 1-day adult    12 carcass, 4-day adult    14 carcass, 20-day adult    17 ovary, virgin 4-day female    44 ovary, mated 4-day female    44 testis, mated 4-day male  (121) accessory gland, mated 4-day male    23 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    82 central nervous system, larvae L3    25 central nervous system, pupae P8    18 head, virgin 1-day female    9 head, virgin 4-day female    17 head, virgin 20-day female    10 head, mated 1-day female    13 head, mated 4-day female    11 head, mated 20-day female    11 head, mated 1-day male    18 head, mated 4-day male    18 head, mated 20-day male    23 salivary gland, larvae L3 wandering    11 salivary gland, white prepupae    21 digestive system, larvae L3 wandering    33 digestive system, 1-day adult    16 digestive system, 4-day adult    17 digestive system, 20-day adult    16 fat body, larvae L3 wandering    9 fat body, white prepupae    25 fat body, pupae P8    76 carcass, larvae L3 wandering    21 carcass, 1-day adult    12 carcass, 4-day adult    14 carcass, 20-day adult    17 ovary, virgin 4-day female    44 ovary, mated 4-day female    44 testis, mated 4-day male    121 accessory gland, mated 4-day male    23 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    82 central nervous system, larvae L3    25 central nervous system, pupae P8    18 head, virgin 1-day female    9 head, virgin 4-day female    17 head, virgin 20-day female    10 head, mated 1-day female    13 head, mated 4-day female    11 head, mated 20-day female    11 head, mated 1-day male    18 head, mated 4-day male    18 head, mated 20-day male    23 salivary gland, larvae L3 wandering    11 salivary gland, white prepupae    21 digestive system, larvae L3 wandering    33 digestive system, 1-day adult    16 digestive system, 4-day adult    17 digestive system, 20-day adult    16 fat body, larvae L3 wandering    9 fat body, white prepupae    25 fat body, pupae P8    76 carcass, larvae L3 wandering    21 carcass, 1-day adult    12 carcass, 4-day adult    14 carcass, 20-day adult    17 ovary, virgin 4-day female    44 ovary, mated 4-day female    44 testis, mated 4-day male    121 accessory gland, mated 4-day male    23 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (82) central nervous system, larvae L3    25 central nervous system, pupae P8    18 head, virgin 1-day female    9 head, virgin 4-day female    17 head, virgin 20-day female    10 head, mated 1-day female    13 head, mated 4-day female    11 head, mated 20-day female    11 head, mated 1-day male    18 head, mated 4-day male    18 head, mated 20-day male    23 salivary gland, larvae L3 wandering    11 salivary gland, white prepupae    21 digestive system, larvae L3 wandering  (33) digestive system, 1-day adult    16 digestive system, 4-day adult    17 digestive system, 20-day adult    16 fat body, larvae L3 wandering    9 fat body, white prepupae    25 fat body, pupae P8  (76) carcass, larvae L3 wandering    21 carcass, 1-day adult    12 carcass, 4-day adult    14 carcass, 20-day adult    17 ovary, virgin 4-day female  (44) ovary, mated 4-day female  (44) testis, mated 4-day male  (121) accessory gland, mated 4-day male    23 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    82 central nervous system, larvae L3    25 central nervous system, pupae P8    18 head, virgin 1-day female    9 head, virgin 4-day female    17 head, virgin 20-day female    10 head, mated 1-day female    13 head, mated 4-day female    11 head, mated 20-day female    11 head, mated 1-day male    18 head, mated 4-day male    18 head, mated 20-day male    23 salivary gland, larvae L3 wandering    11 salivary gland, white prepupae    21 digestive system, larvae L3 wandering    33 digestive system, 1-day adult    16 digestive system, 4-day adult    17 digestive system, 20-day adult    16 fat body, larvae L3 wandering    9 fat body, white prepupae    25 fat body, pupae P8    76 carcass, larvae L3 wandering    21 carcass, 1-day adult    12 carcass, 4-day adult    14 carcass, 20-day adult    17 ovary, virgin 4-day female    44 ovary, mated 4-day female    44 testis, mated 4-day male  121 accessory gland, mated 4-day male    23 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    82 central nervous system, larvae L3    25 central nervous system, pupae P8    18 head, virgin 1-day female    9 head, virgin 4-day female    17 head, virgin 20-day female    10 head, mated 1-day female    13 head, mated 4-day female    11 head, mated 20-day female    11 head, mated 1-day male    18 head, mated 4-day male    18 head, mated 20-day male    23 salivary gland, larvae L3 wandering    11 salivary gland, white prepupae    21 digestive system, larvae L3 wandering    33 digestive system, 1-day adult    16 digestive system, 4-day adult    17 digestive system, 20-day adult    16 fat body, larvae L3 wandering    9 fat body, white prepupae    25 fat body, pupae P8    76 carcass, larvae L3 wandering    21 carcass, 1-day adult    12 carcass, 4-day adult    14 carcass, 20-day adult    17 ovary, virgin 4-day female    44 ovary, mated 4-day female    44 testis, mated 4-day male    121 accessory gland, mated 4-day male    23 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed within 00-12 and 18-24 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in stages of adults of both sexes. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    36 embryo 02-04hr    33 embryo 04-06hr    24 embryo 06-08hr    22 embryo 08-10hr    22 embryo 10-12hr    15 embryo 12-14hr    15 embryo 14-16hr    18 embryo 16-18hr    17 embryo 18-20hr    15 embryo 20-22hr    21 embryo 22-24hr    21 larva L1    13 larva L2    12 larva L3 12hr old    12 larva L3 puffstage 1-2    14 larva L3 puffstage 3-6    18 larva L3 puffstage 7-9    21 white prepupae new    21 white prepupae 12hr    45 white prepupae 24hr    41 pupae 2d postWPP    32 pupae 3d postWPP    25 pupae 4d postWPP    19 adult male 01day    22 adult male 05day    30 adult male 30day    30 adult female 01day    18 adult female 05day    24 adult female 30day    24 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (36) embryo 02-04hr  (33) embryo 04-06hr    24 embryo 06-08hr    22 embryo 08-10hr    22 embryo 10-12hr    15 embryo 12-14hr    15 embryo 14-16hr    18 embryo 16-18hr    17 embryo 18-20hr    15 embryo 20-22hr    21 embryo 22-24hr    21 larva L1    13 larva L2    12 larva L3 12hr old    12 larva L3 puffstage 1-2    14 larva L3 puffstage 3-6    18 larva L3 puffstage 7-9    21 white prepupae new    21 white prepupae 12hr  (45) white prepupae 24hr  (41) pupae 2d postWPP  (32) pupae 3d postWPP    25 pupae 4d postWPP    19 adult male 01day    22 adult male 05day  (30) adult male 30day  (30) adult female 01day    18 adult female 05day    24 adult female 30day    24 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    36 embryo 02-04hr    33 embryo 04-06hr    24 embryo 06-08hr    22 embryo 08-10hr    22 embryo 10-12hr    15 embryo 12-14hr    15 embryo 14-16hr    18 embryo 16-18hr    17 embryo 18-20hr    15 embryo 20-22hr    21 embryo 22-24hr    21 larva L1    13 larva L2    12 larva L3 12hr old    12 larva L3 puffstage 1-2    14 larva L3 puffstage 3-6    18 larva L3 puffstage 7-9    21 white prepupae new    21 white prepupae 12hr    45 white prepupae 24hr    41 pupae 2d postWPP    32 pupae 3d postWPP    25 pupae 4d postWPP    19 adult male 01day    22 adult male 05day    30 adult male 30day    30 adult female 01day    18 adult female 05day    24 adult female 30day    24 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    36 embryo 02-04hr    33 embryo 04-06hr    24 embryo 06-08hr    22 embryo 08-10hr    22 embryo 10-12hr    15 embryo 12-14hr    15 embryo 14-16hr    18 embryo 16-18hr    17 embryo 18-20hr    15 embryo 20-22hr    21 embryo 22-24hr    21 larva L1    13 larva L2    12 larva L3 12hr old    12 larva L3 puffstage 1-2    14 larva L3 puffstage 3-6    18 larva L3 puffstage 7-9    21 white prepupae new    21 white prepupae 12hr    45 white prepupae 24hr    41 pupae 2d postWPP    32 pupae 3d postWPP    25 pupae 4d postWPP    19 adult male 01day    22 adult male 05day    30 adult male 30day    30 adult female 01day    18 adult female 05day    24 adult female 30day    24 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    36 embryo 02-04hr    33 embryo 04-06hr    24 embryo 06-08hr    22 embryo 08-10hr    22 embryo 10-12hr    15 embryo 12-14hr    15 embryo 14-16hr    18 embryo 16-18hr    17 embryo 18-20hr    15 embryo 20-22hr    21 embryo 22-24hr    21 larva L1    13 larva L2    12 larva L3 12hr old    12 larva L3 puffstage 1-2    14 larva L3 puffstage 3-6    18 larva L3 puffstage 7-9    21 white prepupae new    21 white prepupae 12hr    45 white prepupae 24hr    41 pupae 2d postWPP    32 pupae 3d postWPP    25 pupae 4d postWPP    19 adult male 01day    22 adult male 05day    30 adult male 30day    30 adult female 01day    18 adult female 05day    24 adult female 30day    24 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (36) embryo 02-04hr  (33) embryo 04-06hr    24 embryo 06-08hr    22 embryo 08-10hr    22 embryo 10-12hr    15 embryo 12-14hr    15 embryo 14-16hr    18 embryo 16-18hr    17 embryo 18-20hr    15 embryo 20-22hr    21 embryo 22-24hr    21 larva L1    13 larva L2    12 larva L3 12hr old    12 larva L3 puffstage 1-2    14 larva L3 puffstage 3-6    18 larva L3 puffstage 7-9    21 white prepupae new    21 white prepupae 12hr  (45) white prepupae 24hr  (41) pupae 2d postWPP  32 pupae 3d postWPP    25 pupae 4d postWPP    19 adult male 01day    22 adult male 05day  30 adult male 30day  30 adult female 01day    18 adult female 05day    24 adult female 30day    24 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    36 embryo 02-04hr    33 embryo 04-06hr    24 embryo 06-08hr    22 embryo 08-10hr    22 embryo 10-12hr    15 embryo 12-14hr    15 embryo 14-16hr    18 embryo 16-18hr    17 embryo 18-20hr    15 embryo 20-22hr    21 embryo 22-24hr    21 larva L1    13 larva L2    12 larva L3 12hr old    12 larva L3 puffstage 1-2    14 larva L3 puffstage 3-6    18 larva L3 puffstage 7-9    21 white prepupae new    21 white prepupae 12hr    45 white prepupae 24hr    41 pupae 2d postWPP    32 pupae 3d postWPP    25 pupae 4d postWPP    19 adult male 01day    22 adult male 05day    30 adult male 30day    30 adult female 01day    18 adult female 05day    24 adult female 30day    24 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    36 embryo 02-04hr    33 embryo 04-06hr    24 embryo 06-08hr    22 embryo 08-10hr    22 embryo 10-12hr    15 embryo 12-14hr    15 embryo 14-16hr    18 embryo 16-18hr    17 embryo 18-20hr    15 embryo 20-22hr    21 embryo 22-24hr    21 larva L1    13 larva L2    12 larva L3 12hr old    12 larva L3 puffstage 1-2    14 larva L3 puffstage 3-6    18 larva L3 puffstage 7-9    21 white prepupae new    21 white prepupae 12hr    45 white prepupae 24hr    41 pupae 2d postWPP    32 pupae 3d postWPP    25 pupae 4d postWPP    19 adult male 01day    22 adult male 05day    30 adult male 30day    30 adult female 01day    18 adult female 05day    24 adult female 30day    24 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    20 Schneider line 2 Sg4    18 embryonic 1182-4H    38 embryonic GM2    16 embryonic Kc167    14 embryonic S1    28 embryonic S3    29 leg disc CME L1    38 wing disc CME-W2    19 wing disc ML-DmD8    24 wing disc ML-DmD9    31 wing disc ML-DmD16-c3    22 wing disc ML-DmD21    23 wing disc ML-DmD32    13 haltere disc ML-DmD17-c3    36 eye-antennal disc ML-DmD11    23 antennal disc ML-DmD20-c5    34 mixed discs ML-DmD4-c1    27 CNS ML-DmBG1-c1    40 CNS ML-DmBG2-c2    17 tumorous blood cells mbn2    12 ovary fGS/OSS    37 ovary OSC    30 ovary OSS    11 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    20 Schneider line 2 Sg4    18 embryonic 1182-4H  (38) embryonic GM2    16 embryonic Kc167    14 embryonic S1  (28) embryonic S3  (29) leg disc CME L1  (38) wing disc CME-W2    19 wing disc ML-DmD8    24 wing disc ML-DmD9  (31) wing disc ML-DmD16-c3    22 wing disc ML-DmD21    23 wing disc ML-DmD32    13 haltere disc ML-DmD17-c3  (36) eye-antennal disc ML-DmD11    23 antennal disc ML-DmD20-c5  (34) mixed discs ML-DmD4-c1  (27) CNS ML-DmBG1-c1  (40) CNS ML-DmBG2-c2    17 tumorous blood cells mbn2    12 ovary fGS/OSS  (37) ovary OSC  (30) ovary OSS    11 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    20 Schneider line 2 Sg4    18 embryonic 1182-4H    38 embryonic GM2    16 embryonic Kc167    14 embryonic S1    28 embryonic S3    29 leg disc CME L1    38 wing disc CME-W2    19 wing disc ML-DmD8    24 wing disc ML-DmD9    31 wing disc ML-DmD16-c3    22 wing disc ML-DmD21    23 wing disc ML-DmD32    13 haltere disc ML-DmD17-c3    36 eye-antennal disc ML-DmD11    23 antennal disc ML-DmD20-c5    34 mixed discs ML-DmD4-c1    27 CNS ML-DmBG1-c1    40 CNS ML-DmBG2-c2    17 tumorous blood cells mbn2    12 ovary fGS/OSS    37 ovary OSC    30 ovary OSS    11 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    20 Schneider line 2 Sg4    18 embryonic 1182-4H    38 embryonic GM2    16 embryonic Kc167    14 embryonic S1    28 embryonic S3    29 leg disc CME L1    38 wing disc CME-W2    19 wing disc ML-DmD8    24 wing disc ML-DmD9    31 wing disc ML-DmD16-c3    22 wing disc ML-DmD21    23 wing disc ML-DmD32    13 haltere disc ML-DmD17-c3    36 eye-antennal disc ML-DmD11    23 antennal disc ML-DmD20-c5    34 mixed discs ML-DmD4-c1    27 CNS ML-DmBG1-c1    40 CNS ML-DmBG2-c2    17 tumorous blood cells mbn2    12 ovary fGS/OSS    37 ovary OSC    30 ovary OSS    11 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    20 Schneider line 2 Sg4    18 embryonic 1182-4H    38 embryonic GM2    16 embryonic Kc167    14 embryonic S1    28 embryonic S3    29 leg disc CME L1    38 wing disc CME-W2    19 wing disc ML-DmD8    24 wing disc ML-DmD9    31 wing disc ML-DmD16-c3    22 wing disc ML-DmD21    23 wing disc ML-DmD32    13 haltere disc ML-DmD17-c3    36 eye-antennal disc ML-DmD11    23 antennal disc ML-DmD20-c5    34 mixed discs ML-DmD4-c1    27 CNS ML-DmBG1-c1    40 CNS ML-DmBG2-c2    17 tumorous blood cells mbn2    12 ovary fGS/OSS    37 ovary OSC    30 ovary OSS    11 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    20 Schneider line 2 Sg4    18 embryonic 1182-4H  (38) embryonic GM2    16 embryonic Kc167    14 embryonic S1  28 embryonic S3  29 leg disc CME L1  (38) wing disc CME-W2    19 wing disc ML-DmD8    24 wing disc ML-DmD9  31 wing disc ML-DmD16-c3    22 wing disc ML-DmD21    23 wing disc ML-DmD32    13 haltere disc ML-DmD17-c3  (36) eye-antennal disc ML-DmD11    23 antennal disc ML-DmD20-c5  (34) mixed discs ML-DmD4-c1  27 CNS ML-DmBG1-c1  (40) CNS ML-DmBG2-c2    17 tumorous blood cells mbn2    12 ovary fGS/OSS  (37) ovary OSC  30 ovary OSS    11 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    20 Schneider line 2 Sg4    18 embryonic 1182-4H    38 embryonic GM2    16 embryonic Kc167    14 embryonic S1    28 embryonic S3    29 leg disc CME L1    38 wing disc CME-W2    19 wing disc ML-DmD8    24 wing disc ML-DmD9    31 wing disc ML-DmD16-c3    22 wing disc ML-DmD21    23 wing disc ML-DmD32    13 haltere disc ML-DmD17-c3    36 eye-antennal disc ML-DmD11    23 antennal disc ML-DmD20-c5    34 mixed discs ML-DmD4-c1    27 CNS ML-DmBG1-c1    40 CNS ML-DmBG2-c2    17 tumorous blood cells mbn2    12 ovary fGS/OSS    37 ovary OSC    30 ovary OSS    11 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    20 Schneider line 2 Sg4    18 embryonic 1182-4H    38 embryonic GM2    16 embryonic Kc167    14 embryonic S1    28 embryonic S3    29 leg disc CME L1    38 wing disc CME-W2    19 wing disc ML-DmD8    24 wing disc ML-DmD9    31 wing disc ML-DmD16-c3    22 wing disc ML-DmD21    23 wing disc ML-DmD32    13 haltere disc ML-DmD17-c3    36 eye-antennal disc ML-DmD11    23 antennal disc ML-DmD20-c5    34 mixed discs ML-DmD4-c1    27 CNS ML-DmBG1-c1    40 CNS ML-DmBG2-c2    17 tumorous blood cells mbn2    12 ovary fGS/OSS    37 ovary OSC    30 ovary OSS    11 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    21 cold shock, 4-day adult    15 heat shock, 4-day adult    24 Cadmium 50 mM 6 hrs, larvae L3    11 Cadmium 50 mM 12 hrs, larvae L3    18 Cadmium 50 mM 48 hrs, 4-day adult    20 Cadmium 100 mM 48 hrs, 4-day adult    41 Copper 0.5 mM 12 hrs, larvae L3    15 Copper 15 mM 48 hrs, 4-day adult    32 Zinc 5 mM 12 hrs, larvae L3    12 Zinc 4.5 mM 48 hrs, 4-day adult    23 Ethanol 2.5% 3 hrs, larvae L3    31 Ethanol 5% 3 hrs, larvae L3    14 Ethanol 10% 3 hrs, larvae L3    15 Caffeine 1.5 mg/ml 4 hrs, larvae L3    18 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    38 Caffeine 25 mg/ml 48 hrs, 4-day adult    20 Paraquat 5 mM 48 hrs, 4-day adult    34 Paraquat 10 mM 48 hrs, 4-day adult    32 Rotenone 2 μg 12 hrs, larvae L3    16 Rotenone 8 μg 12 hrs, larvae L3    16 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    21 cold shock, 4-day adult    15 heat shock, 4-day adult    24 Cadmium 50 mM 6 hrs, larvae L3    11 Cadmium 50 mM 12 hrs, larvae L3    18 Cadmium 50 mM 48 hrs, 4-day adult    20 Cadmium 100 mM 48 hrs, 4-day adult  (41) Copper 0.5 mM 12 hrs, larvae L3    15 Copper 15 mM 48 hrs, 4-day adult  (32) Zinc 5 mM 12 hrs, larvae L3    12 Zinc 4.5 mM 48 hrs, 4-day adult    23 Ethanol 2.5% 3 hrs, larvae L3  (31) Ethanol 5% 3 hrs, larvae L3    14 Ethanol 10% 3 hrs, larvae L3    15 Caffeine 1.5 mg/ml 4 hrs, larvae L3    18 Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (38) Caffeine 25 mg/ml 48 hrs, 4-day adult    20 Paraquat 5 mM 48 hrs, 4-day adult  (34) Paraquat 10 mM 48 hrs, 4-day adult  (32) Rotenone 2 μg 12 hrs, larvae L3    16 Rotenone 8 μg 12 hrs, larvae L3    16 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    21 cold shock, 4-day adult    15 heat shock, 4-day adult    24 Cadmium 50 mM 6 hrs, larvae L3    11 Cadmium 50 mM 12 hrs, larvae L3    18 Cadmium 50 mM 48 hrs, 4-day adult    20 Cadmium 100 mM 48 hrs, 4-day adult    41 Copper 0.5 mM 12 hrs, larvae L3    15 Copper 15 mM 48 hrs, 4-day adult    32 Zinc 5 mM 12 hrs, larvae L3    12 Zinc 4.5 mM 48 hrs, 4-day adult    23 Ethanol 2.5% 3 hrs, larvae L3    31 Ethanol 5% 3 hrs, larvae L3    14 Ethanol 10% 3 hrs, larvae L3    15 Caffeine 1.5 mg/ml 4 hrs, larvae L3    18 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    38 Caffeine 25 mg/ml 48 hrs, 4-day adult    20 Paraquat 5 mM 48 hrs, 4-day adult    34 Paraquat 10 mM 48 hrs, 4-day adult    32 Rotenone 2 μg 12 hrs, larvae L3    16 Rotenone 8 μg 12 hrs, larvae L3    16 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    21 cold shock, 4-day adult    15 heat shock, 4-day adult    24 Cadmium 50 mM 6 hrs, larvae L3    11 Cadmium 50 mM 12 hrs, larvae L3    18 Cadmium 50 mM 48 hrs, 4-day adult    20 Cadmium 100 mM 48 hrs, 4-day adult    41 Copper 0.5 mM 12 hrs, larvae L3    15 Copper 15 mM 48 hrs, 4-day adult    32 Zinc 5 mM 12 hrs, larvae L3    12 Zinc 4.5 mM 48 hrs, 4-day adult    23 Ethanol 2.5% 3 hrs, larvae L3    31 Ethanol 5% 3 hrs, larvae L3    14 Ethanol 10% 3 hrs, larvae L3    15 Caffeine 1.5 mg/ml 4 hrs, larvae L3    18 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    38 Caffeine 25 mg/ml 48 hrs, 4-day adult    20 Paraquat 5 mM 48 hrs, 4-day adult    34 Paraquat 10 mM 48 hrs, 4-day adult    32 Rotenone 2 μg 12 hrs, larvae L3    16 Rotenone 8 μg 12 hrs, larvae L3    16 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    21 cold shock, 4-day adult    15 heat shock, 4-day adult    24 Cadmium 50 mM 6 hrs, larvae L3    11 Cadmium 50 mM 12 hrs, larvae L3    18 Cadmium 50 mM 48 hrs, 4-day adult    20 Cadmium 100 mM 48 hrs, 4-day adult    41 Copper 0.5 mM 12 hrs, larvae L3    15 Copper 15 mM 48 hrs, 4-day adult    32 Zinc 5 mM 12 hrs, larvae L3    12 Zinc 4.5 mM 48 hrs, 4-day adult    23 Ethanol 2.5% 3 hrs, larvae L3    31 Ethanol 5% 3 hrs, larvae L3    14 Ethanol 10% 3 hrs, larvae L3    15 Caffeine 1.5 mg/ml 4 hrs, larvae L3    18 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    38 Caffeine 25 mg/ml 48 hrs, 4-day adult    20 Paraquat 5 mM 48 hrs, 4-day adult    34 Paraquat 10 mM 48 hrs, 4-day adult    32 Rotenone 2 μg 12 hrs, larvae L3    16 Rotenone 8 μg 12 hrs, larvae L3    16 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    21 cold shock, 4-day adult    15 heat shock, 4-day adult    24 Cadmium 50 mM 6 hrs, larvae L3    11 Cadmium 50 mM 12 hrs, larvae L3    18 Cadmium 50 mM 48 hrs, 4-day adult    20 Cadmium 100 mM 48 hrs, 4-day adult  (41) Copper 0.5 mM 12 hrs, larvae L3    15 Copper 15 mM 48 hrs, 4-day adult  32 Zinc 5 mM 12 hrs, larvae L3    12 Zinc 4.5 mM 48 hrs, 4-day adult    23 Ethanol 2.5% 3 hrs, larvae L3  31 Ethanol 5% 3 hrs, larvae L3    14 Ethanol 10% 3 hrs, larvae L3    15 Caffeine 1.5 mg/ml 4 hrs, larvae L3    18 Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (38) Caffeine 25 mg/ml 48 hrs, 4-day adult    20 Paraquat 5 mM 48 hrs, 4-day adult  (34) Paraquat 10 mM 48 hrs, 4-day adult  32 Rotenone 2 μg 12 hrs, larvae L3    16 Rotenone 8 μg 12 hrs, larvae L3    16 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    21 cold shock, 4-day adult    15 heat shock, 4-day adult    24 Cadmium 50 mM 6 hrs, larvae L3    11 Cadmium 50 mM 12 hrs, larvae L3    18 Cadmium 50 mM 48 hrs, 4-day adult    20 Cadmium 100 mM 48 hrs, 4-day adult    41 Copper 0.5 mM 12 hrs, larvae L3    15 Copper 15 mM 48 hrs, 4-day adult    32 Zinc 5 mM 12 hrs, larvae L3    12 Zinc 4.5 mM 48 hrs, 4-day adult    23 Ethanol 2.5% 3 hrs, larvae L3    31 Ethanol 5% 3 hrs, larvae L3    14 Ethanol 10% 3 hrs, larvae L3    15 Caffeine 1.5 mg/ml 4 hrs, larvae L3    18 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    38 Caffeine 25 mg/ml 48 hrs, 4-day adult    20 Paraquat 5 mM 48 hrs, 4-day adult    34 Paraquat 10 mM 48 hrs, 4-day adult    32 Rotenone 2 μg 12 hrs, larvae L3    16 Rotenone 8 μg 12 hrs, larvae L3    16 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    21 cold shock, 4-day adult    15 heat shock, 4-day adult    24 Cadmium 50 mM 6 hrs, larvae L3    11 Cadmium 50 mM 12 hrs, larvae L3    18 Cadmium 50 mM 48 hrs, 4-day adult    20 Cadmium 100 mM 48 hrs, 4-day adult    41 Copper 0.5 mM 12 hrs, larvae L3    15 Copper 15 mM 48 hrs, 4-day adult    32 Zinc 5 mM 12 hrs, larvae L3    12 Zinc 4.5 mM 48 hrs, 4-day adult    23 Ethanol 2.5% 3 hrs, larvae L3    31 Ethanol 5% 3 hrs, larvae L3    14 Ethanol 10% 3 hrs, larvae L3    15 Caffeine 1.5 mg/ml 4 hrs, larvae L3    18 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    38 Caffeine 25 mg/ml 48 hrs, 4-day adult    20 Paraquat 5 mM 48 hrs, 4-day adult    34 Paraquat 10 mM 48 hrs, 4-day adult    32 Rotenone 2 μg 12 hrs, larvae L3    16 Rotenone 8 μg 12 hrs, larvae L3    16 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_27 mE1_20_mRNA_expression_cluster_09
External Data & Images
Linkouts	BDGP expression data • GH06403 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0036020 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG8336-RB FlyExpress - Embryonic expression images (BDGP data) • Show all FlyExpress processed images for CG8336 Stages(s) 1-3 Stages(s) 4-6 Stages(s) 7-8 Stages(s) 9-10 Stages(s) 11-12
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable, with Scer\GAL4pnr-MD237 CG8336GD13759 Phenotype manifest in Allele
Classical Alleles ( 2 )
For All Classical Alleles Show
Allele of CG8336 Class Mutagen Stocks Known lesion CG8336MB04909 1 -- CG8336NP4480 1 --
Alleles Carried on Transgenic Constructs ( 2 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG8336 Class Mutagen Stocks Known lesion CG8336GD13759 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG8336NIG.8336R in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(3L)Exel6114 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD13759} NA P{NIG.8336R} NA
Insertions
	Type of insertions Name Expression data insertion of enhancer trap binary system Mi{ET1}Or67bMB04909 No P{GawB}CG8336NP4480 No
Gene Ontology: Function, Process & Cellular Component ( 2 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 2 terms )
Molecular Function
CV term Evidence References
peptidyl-prolyl cis-trans isomerase activity inferred from electronic annotation with InterPro:IPR002130 (FlyBase Curators et al., 2004-)
Biological Process
CV term Evidence References
protein folding inferred from electronic annotation with InterPro:IPR002130 (FlyBase Curators et al., 2004-)
Cellular Component ( 0 terms)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
protein-protein
Interacting group Assay References
CG8336 - 14-3-3ζ anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG8336 - Atx2 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG8336 - CG10077 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG8336 - CG10418 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG8336 - CG11107 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG8336 - CG11266 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG8336 - CG13472 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG8336 - CG15735 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG8336 - CG17454 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG8336 - CG3689 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG8336 - CG3731 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG8336 - CG4611 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG8336 - CG4612 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG8336 - CG5726 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG8336 - CG5746 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG8336 - CG5792 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG8336 - CG6412 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG8336 - CG7878 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG8336 - CG7903 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG8336 - CG8021 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG8336 - CG8036 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG8336 - CG9775 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG8336 - Cdc5 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG8336 - Fmr1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG8336 - Gale anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG8336 - Grp anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG8336 - Hsc70-1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG8336 - Hsp68 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG8336 - Imp anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG8336 - Rab5 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG8336 - Rbp1-like anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG8336 - RpL35A anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG8336 - RpS19b anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG8336 - Rsf1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG8336 - SC35 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG8336 - SF1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG8336 - Saf-B anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG8336 - Sec23 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG8336 - SmD3 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG8336 - SmG anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG8336 - Syp anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG8336 - Tim8 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG8336 - Tm1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG8336 - Trap1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG8336 - Upf1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG8336 - Zn72D anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG8336 - btz anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG8336 - cathD anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG8336 - eIF4AIII anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG8336 - isoQC anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG8336 - mRpL43 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG8336 - mRpL44 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG8336 - miple2 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG8336 - mod anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG8336 - par-1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG8336 - qkr58E-3 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG8336 - ssx anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23)
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG8336 allele Gene References
External Data
Linkouts	DPiM - DPiM, Drosophila Protein interaction Map • FBgn0036020 DroID - A comprehensive database of gene and protein interactions. • FBgn0036020 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 39121
Orthologs
OrthoDB Orthologs (113) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6DR9ZB Dipteran inclusive ortholog search EOG6FXRH7 Insect inclusive ortholog search EOG6JM6KD Arthropod inclusive ortholog search EOG6SQVCC Metazoa inclusive ortholog search EOG651SJN
Orthologs in Drosophila Species (EOG6DR9ZB)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\CG8336     Drosophila simulans   Dsim\GD14199 Y   Drosophila sechellia   Dsec\GM25168 Y   Drosophila erecta   Dere\GG15394 Y   Drosophila yakuba   Dyak\GE20859 Y   Drosophila ananassae   Dana\GF25145 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA20999 Y   Drosophila persimilis   Dper\GL12709 Y   Drosophila willistoni   Dwil\GK16621 Y   Drosophila virilis   Dvir\GJ12024 Y   Drosophila mojavensis   Dmoj\GI13253 Y   Drosophila grimshawi   Dgri\GH16309 Y
Orthologs in non-Drosophila Dipterans (EOG6FXRH7)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL000013   Anopheles gambiae Malaria mosquito  Agam\AGAP003265   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ016592
Orthologs in non-Dipteran Insects (EOG6JM6KD)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\GB55626   Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG015596   Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH13761   Atta cephalotes Leafcutter ant  Acep\ACEP23167   Camponotus floridanus Florida carpenter ant  Cflo\CFLO19009   Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL19913   Linepithema humile Argentine ant  Lhum\LH14953   Pogonomyrmex barbatus Red harvester ant  Pbar\PB12975   Solenopsis invicta Red fire ant  Sinv\SINV18820   Acyrthosiphon pisum Pea aphid  Apim\ACYPI53623   Acyrthosiphon pisum Pea aphid  Apim\ACYPI53622   Bombyx mori Silkmoth  Bmor\BGIBMGA009341   Pediculus humanus Human body louse  Phum\PHUM474930   Tribolium castaneum Red flour beetle  Tcas\GLEAN_07008
Orthologs in non-Insect Arthropods (EOG6SQVCC)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Ixodes scapularis Deer tick  Isca\ISCW014907
Orthologs in non-Arthropod Metazoa (EOG651SJN)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Caenorhabditis elegans Nematode  Cele\cyn-9 Y Caenorhabditis elegans Nematode  Cele\cyn-11 Y Caenorhabditis elegans Nematode  Cele\cyn-1 Y Caenorhabditis elegans Nematode  Cele\cyn-2 Y Caenorhabditis elegans Nematode  Cele\cyn-13 Y Caenorhabditis elegans Nematode  Cele\cyn-3 Y Caenorhabditis elegans Nematode  Cele\cyn-7 Y Caenorhabditis elegans Nematode  Cele\cyn-8 Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_003109gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_002789gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_028896gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_015311gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_015986gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_000637gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_002790gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_022735gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_008305gn Y Danio rerio Zebrafish  Drer\ppial Y Danio rerio Zebrafish  Drer\ppif Y Danio rerio Zebrafish  Drer\ppil6 Y Danio rerio Zebrafish  Drer\zgc:123307 Y Danio rerio Zebrafish  Drer\ppig Y Danio rerio Zebrafish  Drer\nktr Y Danio rerio Zebrafish  Drer\ppih Y Danio rerio Zebrafish  Drer\ppia Y Danio rerio Zebrafish  Drer\ppie Y Danio rerio Zebrafish  Drer\ENSDARG00000087128 Y Xenopus tropicalis Western clawed frog  Xtro\ppie Y Xenopus tropicalis Western clawed frog  Xtro\ppia Y Xenopus tropicalis Western clawed frog  Xtro\ppil6 Y Xenopus tropicalis Western clawed frog  Xtro\ENSXETG00000025399 Y Xenopus tropicalis Western clawed frog  Xtro\nktr Y Xenopus tropicalis Western clawed frog  Xtro\ppih Y Xenopus tropicalis Western clawed frog  Xtro\ppid Y Gallus gallus Domestic chicken  Ggal\PPIH Y Gallus gallus Domestic chicken  Ggal\PPIL6 Y Gallus gallus Domestic chicken  Ggal\PPIF Y Gallus gallus Domestic chicken  Ggal\PPIE Y Gallus gallus Domestic chicken  Ggal\PPID Y Gallus gallus Domestic chicken  Ggal\NKTR Y Gallus gallus Domestic chicken  Ggal\PPIG Y Mus musculus House mouse  Mmus\Ppil6 Y Mus musculus House mouse  Mmus\Ppif Y Mus musculus House mouse  Mmus\Gm9234 Y Mus musculus House mouse  Mmus\Ppia Y Mus musculus House mouse  Mmus\Nktr Y Mus musculus House mouse  Mmus\Ppig Y Mus musculus House mouse  Mmus\Gm5160 Y Mus musculus House mouse  Mmus\ENSMUSG00000091052 Y Mus musculus House mouse  Mmus\Ppia Y Mus musculus House mouse  Mmus\Ppie Y Mus musculus House mouse  Mmus\Ppid Y Mus musculus House mouse  Mmus\Ppih Y Rattus norvegicus Norway rat  Rnor\Ppia Y Rattus norvegicus Norway rat  Rnor\Ppig Y Rattus norvegicus Norway rat  Rnor\Ppie Y Rattus norvegicus Norway rat  Rnor\Ppia Y Rattus norvegicus Norway rat  Rnor\ENSRNOG00000030050 Y Rattus norvegicus Norway rat  Rnor\ENSRNOG00000036609 Y Rattus norvegicus Norway rat  Rnor\Ppif Y Rattus norvegicus Norway rat  Rnor\ENSRNOG00000023821 Y Rattus norvegicus Norway rat  Rnor\ENSRNOG00000008489 Y Rattus norvegicus Norway rat  Rnor\Ppid Y Rattus norvegicus Norway rat  Rnor\ENSRNOG00000023461 Y Rattus norvegicus Norway rat  Rnor\ENSRNOG00000027085 Y Rattus norvegicus Norway rat  Rnor\ENSRNOG00000024916 Y Rattus norvegicus Norway rat  Rnor\ENSRNOG00000039269 Y Rattus norvegicus Norway rat  Rnor\ENSRNOG00000002712 Y Rattus norvegicus Norway rat  Rnor\Ppil6 Y Rattus norvegicus Norway rat  Rnor\ENSRNOG00000031045 Y Homo sapiens Human  Hsap\PPID Y Homo sapiens Human  Hsap\ENSG00000185250 Y Homo sapiens Human  Hsap\ENSG00000255963 Y Homo sapiens Human  Hsap\ENSG00000255854 Y Homo sapiens Human  Hsap\ENSG00000198161 Y Homo sapiens Human  Hsap\NKTR Y Homo sapiens Human  Hsap\PPIE Y Homo sapiens Human  Hsap\PPIAL4D Y Homo sapiens Human  Hsap\PPIH Y Homo sapiens Human  Hsap\PPIA Y Homo sapiens Human  Hsap\PPIF Y Homo sapiens Human  Hsap\PPIAL4G Y Homo sapiens Human  Hsap\PPIG Y
Human Orthologs (13)
Gene OMIM HGNC Hsap\PPID     Hsap\ENSG00000185250     Hsap\ENSG00000255963     Hsap\ENSG00000255854     Hsap\ENSG00000198161     Hsap\NKTR     Hsap\PPIE     Hsap\PPIAL4D     Hsap\PPIH     Hsap\PPIA     Hsap\PPIF     Hsap\PPIAL4G     Hsap\PPIG
AAA Orthologs (11) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD14199 Drosophila sechellia Dsec\GM25168 Drosophila erecta Dere\GG15394 Drosophila yakuba Dyak\GE20859 Drosophila ananassae Dana\GF25145 Drosophila pseudoobscura pseudoobscura Dpse\GA20999 Drosophila persimilis Dper\GL12709 Drosophila willistoni Dwil\GK16621 Drosophila virilis Dvir\GJ12024 Drosophila mojavensis Dmoj\GI13253 Drosophila grimshawi Dgri\GH16309
Stocks & Reagents
Stocks Listed in FlyBase ( 3 )
Bloomington	24728 w1118; Mi{ET1}Or67bMB04909 CG8336MB04909
Kyoto	104692 y* w*; P{GawB}CG8336NP4480 / TM6, P{UAS-lacZ.UW23-1}UW23-1
VDRC	v23729 w1118; P{GD13759}v23729
Genomic Clones ( 2 )
	BACR02B01 BACR12K04 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 31 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	GH06403
Other clones	DPiM_GH06403
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT03932 AT04719 AT07162 AT09301 AT13143 GH12882 GH20344 LD04787 LD11271 RE51872 RE64420 RE65338
Other clones	AT16219 bs33f02 CK01.16B.E10 EK098534 EK308749 EP08729 RP004027662 RP004098718 RP004204483 RP004209231 RP004211302 RP004247554 RP004304375 RP004363667 RP004450978 RP004513220 RP004528120
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0036020 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 39121
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_140081 NM_168354 NM_168355 NM_001274707 RefSeq (Proteins) • NP_648338 NP_729517 NP_729518 NP_001261636 DDBJ / EMBL / GenBank • AAF50235 AAL13532 AAN11947 AAN11948 AGB94331 AI107102 AI389222 AI402046 AI946971 AY058303 Entrez Gene - A searchable database of RefSeq genes. • 39121 UniProtKB/TrEMBL • Q9VT21
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Tetratricopeptide TPR2 (IPR013105) Cyclophilin-like peptidyl-prolyl cis-trans isomerase domain (IPR002130) Tetratricopeptide-like helical (IPR011990) Tetratricopeptide repeat-containing domain (IPR013026) Tetratricopeptide repeat (IPR019734) BDGP expression data - Patterns of gene expression in Drosophila embryogenesis • GH06403
Linkouts
	DPiM - DPiM, Drosophila Protein interaction Map • FBgn0036020 DroID - A comprehensive database of gene and protein interactions. • FBgn0036020 DRSC - Results from RNAi screens. • FBgn0036020 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0036020 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG8336-RB FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0036020 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 39121 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 39121 modMine - Data generated by the modENCODE project. • FBgn0036020
Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	CG8336 (Varma and Mishra, 2011, Telonis-Scott et al., 2009, Rollmann et al., 2010, Japanese National Institute of Genetics, 2012.5.21)
Name Synonym
Secondary FlyBase IDs
References ( 17 )
Research paper	Varma and Mishra, 2011, J. Biosci., Bangalore 36(3): 439--459 Dynamics of nuclear matrix proteome during embryonic development in Drosophila melanogaster. [FBrf0214552] Rollmann et al., 2010, Genetics 186(2): 687--697 Odorant receptor polymorphisms and natural variation in olfactory behavior in Drosophila melanogaster. [FBrf0212096] Telonis-Scott et al., 2009, J. Insect Physiol. 55(6): 549--555 Selection for cold resistance alters gene transcript levels in Drosophila melanogaster. [FBrf0208060]
Supplementary material	Graveley et al., 2011, Nature 471(7339): Supplementary Table 33. Fuzzy Cluster Members. [FBrf0213980] The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518]
Personal communication to FlyBase	Mintseris et al., 2009.11.23, DPiM: the Drosophila Protein Interaction Mapping project DPiM: the Drosophila Protein Interaction Mapping project [FBrf0209452] Bellen, 2007.10.30, batch763.xml batch763.xml [FBrf0200261] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] FlyBase Curators et al., 2004-, Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. [FBrf0174215] Ryder, 2004.4.26, Exelixis CG deletion data. Exelixis CG deletion data. [FBrf0184335] Oliver, 2001.8.16, Genome Res.: File from B. Oliver containing information on ESTs expressed in the Drosophila testis, described in Andrews et al., 2000, Genome Res. 10(12): 2030-2043 (FBrf0132348). [FBrf0137492] BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. (Computer file) Berkeley Drosophila Genome Project. (Computer file) [FBrf0125078]
FlyBase analysis	FlyBase Curators, 2008, Insertion identifiers and alleles based on genomic location of insertions with respect to gene annotations. Insertion identifiers and alleles based on genomic location of insertions with respect to gene annotations. [FBrf0202955]
Stock list	Japanese National Institute of Genetics, 2012.5.21, RNAi stocks available from NIG-FLY. RNAi stocks available from NIG-FLY. [FBrf0218457]
Website	Fisher et al., 2012, BDGP insitu homepage BDGP insitu homepage [FBrf0219073]