Gene model reviewed during 5.45
There is only one protein coding transcript and one polypeptide associated with this gene
Belongs to the multiprotein complex Integrator, at least composed of IntS1, IntS2, IntS3, IntS4, omd/IntS5, IntS6, defl/IntS7, IntS8, IntS9, IntS10, IntS11, IntS12, asun/IntS13 and IntS14.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\defl using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\defl in GBrowse 2
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for identity of: defl CG18176
Homozygotes show lethality which varies between alleles and includes both larvae and pupae. Mutant larvae become sluggish and appear developmentally retarded. Pupal lethality is associated with severe defects in abdominal formation.