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Gene Dmel\CG12362

General Information
Symbol	Dmel\CG12362	Species	D. melanogaster
Name		Annotation symbol	CG12362
Feature type	protein_coding_gene	FlyBase ID	FBgn0036082
Gene Model Status	Current	Stock availability	3 publicly available
Genomic Location
Chromosome (arm)	3L	Recombination map
Cytogenetic map	67E2-67E3	Sequence location	3L:10,405,916..10,407,877 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG12362 (FBgn0036082). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function: zinc ion binding. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Zinc finger, C6HC-type; Zinc finger, RING-type; Zinc finger, RING/FYVE/PHD-type. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of no expression detected. Peak expression observed in adult male stages. Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: adult testis. Expression at moderate levels in the following post-embryonic organs or tissues: larval fat body. Comments on Affy2 ProbeSet: ProbeSet 1635753_s_at completely aligns to an exonic region common to each of the 2 FlyBase-annotated transcript isoforms of CG12362. Gene sequence location is 3L:10405916..10407877.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2011_10
FB2012_01	Sequence features HFA09884 BKN31335
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 67E2-67E3   Limits computationally determined from genome sequence between P{lacW}l(3)L0539L0539&P{PZ}Dhh1rL562 and P{PZ}simj01814
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG12362 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG12362-RA FBtr0076282  NM_140135   1898   511 CG12362-RB FBtr0076281  NM_168405   1962   511
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG12362-PA   FBpp0076011   59.5   511   5.01     NP_648392   AAF50159 CG12362-PB   FBpp0076010   59.5   511   5.01     NP_729606   AAN11912
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Zinc finger, RING-type (IPR001841) Zinc finger, C6HC-type (IPR002867) Zinc finger, RING/FYVE/PHD-type (IPR013083)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE014296 AAF50159   AE014296 AAN11912   AI944449   BE976242   BE976303   BE976709   BE977019   BE977310   BE978423   BE978650   BE979066   BF489935   BF499786   BF502127   BF506265   BT003638 AAO39642   CO191626
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9VT94
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0036082    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0036082 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of no expression detected. Peak expression observed in adult male stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0036082 expression level Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    2 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    2 embryo 12-14hr    2 embryo 14-16hr    5 embryo 16-18hr    2 embryo 18-20hr    2 embryo 20-22hr    0 embryo 22-24hr    0 larva L1    0 larva L2    0 larva L3 12hr old    28 larva L3 puffstage 1-2    260 larva L3 puffstage 3-6    501 larva L3 puffstage 7-9    713 white prepupae new    603 white prepupae 12hr    1216 white prepupae 24hr    1475 pupae 2d postWPP    2008 pupae 3d postWPP    2220 pupae 4d postWPP    1704 adult male 01day    3782 adult male 05day    4227 adult male 30day    3773 adult female 01day    2 adult female 05day    0 adult female 30day    0 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    2 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    2 embryo 12-14hr    2 embryo 14-16hr    5 embryo 16-18hr    2 embryo 18-20hr    2 embryo 20-22hr    0 embryo 22-24hr    0 larva L1    0 larva L2    0 larva L3 12hr old    28 larva L3 puffstage 1-2  (260) larva L3 puffstage 3-6  (501) larva L3 puffstage 7-9  (713) white prepupae new  (603) white prepupae 12hr  (1216) white prepupae 24hr  (1475) pupae 2d postWPP  (2008) pupae 3d postWPP  (2220) pupae 4d postWPP  (1704) adult male 01day  (3782) adult male 05day  (4227) adult male 30day  (3773) adult female 01day    2 adult female 05day    0 adult female 30day    0 Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    2 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    2 embryo 12-14hr    2 embryo 14-16hr    5 embryo 16-18hr    2 embryo 18-20hr    2 embryo 20-22hr    0 embryo 22-24hr    0 larva L1    0 larva L2    0 larva L3 12hr old    28 larva L3 puffstage 1-2    260 larva L3 puffstage 3-6    501 larva L3 puffstage 7-9    713 white prepupae new    603 white prepupae 12hr    1216 white prepupae 24hr  1475 pupae 2d postWPP  (2008) pupae 3d postWPP  (2220) pupae 4d postWPP  (1704) adult male 01day  (3782) adult male 05day  (4227) adult male 30day  (3773) adult female 01day    2 adult female 05day    0 adult female 30day    0 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    2 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    2 embryo 12-14hr    2 embryo 14-16hr    5 embryo 16-18hr    2 embryo 18-20hr    2 embryo 20-22hr    0 embryo 22-24hr    0 larva L1    0 larva L2    0 larva L3 12hr old    28 larva L3 puffstage 1-2    260 larva L3 puffstage 3-6    501 larva L3 puffstage 7-9    713 white prepupae new    603 white prepupae 12hr    1216 white prepupae 24hr    1475 pupae 2d postWPP    2008 pupae 3d postWPP    2220 pupae 4d postWPP    1704 adult male 01day    3782 adult male 05day    4227 adult male 30day    3773 adult female 01day    2 adult female 05day    0 adult female 30day    0 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    2 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    2 embryo 12-14hr    2 embryo 14-16hr    5 embryo 16-18hr    2 embryo 18-20hr    2 embryo 20-22hr    0 embryo 22-24hr    0 larva L1    0 larva L2    0 larva L3 12hr old    28 larva L3 puffstage 1-2    260 larva L3 puffstage 3-6    501 larva L3 puffstage 7-9    713 white prepupae new    603 white prepupae 12hr    1216 white prepupae 24hr    1475 pupae 2d postWPP    2008 pupae 3d postWPP    2220 pupae 4d postWPP    1704 adult male 01day    3782 adult male 05day    4227 adult male 30day    3773 adult female 01day    2 adult female 05day    0 adult female 30day    0 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0036082 expression level Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    2 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    2 embryo 12-14hr    2 embryo 14-16hr    5 embryo 16-18hr    2 embryo 18-20hr    2 embryo 20-22hr    0 embryo 22-24hr    0 larva L1    0 larva L2    0 larva L3 12hr old    28 larva L3 puffstage 1-2    260 larva L3 puffstage 3-6    501 larva L3 puffstage 7-9    713 white prepupae new    603 white prepupae 12hr    1216 white prepupae 24hr    1475 pupae 2d postWPP    2008 pupae 3d postWPP    2220 pupae 4d postWPP    1704 adult male 01day    3782 adult male 05day    4227 adult male 30day    3773 adult female 01day    2 adult female 05day    0 adult female 30day    0 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    2 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    2 embryo 12-14hr    2 embryo 14-16hr    5 embryo 16-18hr    2 embryo 18-20hr    2 embryo 20-22hr    0 embryo 22-24hr    0 larva L1    0 larva L2    0 larva L3 12hr old    28 larva L3 puffstage 1-2  (260) larva L3 puffstage 3-6  (501) larva L3 puffstage 7-9  (713) white prepupae new  (603) white prepupae 12hr  (1216) white prepupae 24hr  (1475) pupae 2d postWPP  (2008) pupae 3d postWPP  (2220) pupae 4d postWPP  (1704) adult male 01day  (3782) adult male 05day  (4227) adult male 30day  (3773) adult female 01day    2 adult female 05day    0 adult female 30day    0 Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    2 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    2 embryo 12-14hr    2 embryo 14-16hr    5 embryo 16-18hr    2 embryo 18-20hr    2 embryo 20-22hr    0 embryo 22-24hr    0 larva L1    0 larva L2    0 larva L3 12hr old    28 larva L3 puffstage 1-2    260 larva L3 puffstage 3-6    501 larva L3 puffstage 7-9    713 white prepupae new    603 white prepupae 12hr    1216 white prepupae 24hr  1475 pupae 2d postWPP  2008 pupae 3d postWPP  2220 pupae 4d postWPP  1704 adult male 01day  (3782) adult male 05day  (4227) adult male 30day  (3773) adult female 01day    2 adult female 05day    0 adult female 30day    0 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    2 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    2 embryo 12-14hr    2 embryo 14-16hr    5 embryo 16-18hr    2 embryo 18-20hr    2 embryo 20-22hr    0 embryo 22-24hr    0 larva L1    0 larva L2    0 larva L3 12hr old    28 larva L3 puffstage 1-2    260 larva L3 puffstage 3-6    501 larva L3 puffstage 7-9    713 white prepupae new    603 white prepupae 12hr    1216 white prepupae 24hr    1475 pupae 2d postWPP    2008 pupae 3d postWPP    2220 pupae 4d postWPP    1704 adult male 01day    3782 adult male 05day    4227 adult male 30day    3773 adult female 01day    2 adult female 05day    0 adult female 30day    0 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    2 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    2 embryo 12-14hr    2 embryo 14-16hr    5 embryo 16-18hr    2 embryo 18-20hr    2 embryo 20-22hr    0 embryo 22-24hr    0 larva L1    0 larva L2    0 larva L3 12hr old    28 larva L3 puffstage 1-2    260 larva L3 puffstage 3-6    501 larva L3 puffstage 7-9    713 white prepupae new    603 white prepupae 12hr    1216 white prepupae 24hr    1475 pupae 2d postWPP    2008 pupae 3d postWPP    2220 pupae 4d postWPP    1704 adult male 01day    3782 adult male 05day    4227 adult male 30day    3773 adult female 01day    2 adult female 05day    0 adult female 30day    0 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0036082    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0036082 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: adult testis. Expression at moderate levels in the following post-embryonic organs or tissues: larval fat body. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0036082 expression level Tissue   Expression Level Larval Central Nervous System    2.35 Larval Midgut    1.9 Larval Hindgut    2.3 Larval Malpighian Tubules    1.4 Larval Fat Body    103.7 Larval Salivary Gland    5.7 Larval Trachea    6.875 Larval Carcass    1.875 Adult Head    0.9 Adult Eye    2.55 Adult Brain    4.1 Adult Thoracic-Abdominal Ganglion    2.7 Adult Crop    4 Adult Midgut    3.2 Adult Hindgut    1.3 Adult Malpighian Tubules    3.4 Adult Fat Body    6.4 Adult Salivary Gland    8.8 Adult Heart    2.3 Adult VirginFemale Spermatheca    4.8 Adult InseminatedFemale Spermatheca    9 Adult Ovary    1.1 Adult Testis    1189.7 Adult Male Accessory Gland    5.8 Adult Carcass    7.4 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    2.35 Larval Midgut    1.9 Larval Hindgut    2.3 Larval Malpighian Tubules    1.4 Larval Fat Body    103.7 Larval Salivary Gland    5.7 Larval Trachea    6.875 Larval Carcass    1.875 Adult Head    0.9 Adult Eye    2.55 Adult Brain    4.1 Adult Thoracic-Abdominal Ganglion    2.7 Adult Crop    4 Adult Midgut    3.2 Adult Hindgut    1.3 Adult Malpighian Tubules    3.4 Adult Fat Body    6.4 Adult Salivary Gland    8.8 Adult Heart    2.3 Adult VirginFemale Spermatheca    4.8 Adult InseminatedFemale Spermatheca    9 Adult Ovary    1.1 Adult Testis  (1189.7) Adult Male Accessory Gland    5.8 Adult Carcass    7.4 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    2.35 Larval Midgut    1.9 Larval Hindgut    2.3 Larval Malpighian Tubules    1.4 Larval Fat Body    103.7 Larval Salivary Gland    5.7 Larval Trachea    6.875 Larval Carcass    1.875 Adult Head    0.9 Adult Eye    2.55 Adult Brain    4.1 Adult Thoracic-Abdominal Ganglion    2.7 Adult Crop    4 Adult Midgut    3.2 Adult Hindgut    1.3 Adult Malpighian Tubules    3.4 Adult Fat Body    6.4 Adult Salivary Gland    8.8 Adult Heart    2.3 Adult VirginFemale Spermatheca    4.8 Adult InseminatedFemale Spermatheca    9 Adult Ovary    1.1 Adult Testis  (1189.7) Adult Male Accessory Gland    5.8 Adult Carcass    7.4 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    2.35 Larval Midgut    1.9 Larval Hindgut    2.3 Larval Malpighian Tubules    1.4 Larval Fat Body    103.7 Larval Salivary Gland    5.7 Larval Trachea    6.875 Larval Carcass    1.875 Adult Head    0.9 Adult Eye    2.55 Adult Brain    4.1 Adult Thoracic-Abdominal Ganglion    2.7 Adult Crop    4 Adult Midgut    3.2 Adult Hindgut    1.3 Adult Malpighian Tubules    3.4 Adult Fat Body    6.4 Adult Salivary Gland    8.8 Adult Heart    2.3 Adult VirginFemale Spermatheca    4.8 Adult InseminatedFemale Spermatheca    9 Adult Ovary    1.1 Adult Testis    1189.7 Adult Male Accessory Gland    5.8 Adult Carcass    7.4 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0036082 expression level Tissue   Expression Level Larval Central Nervous System    2.35 Larval Midgut    1.9 Larval Hindgut    2.3 Larval Malpighian Tubules    1.4 Larval Fat Body    103.7 Larval Salivary Gland    5.7 Larval Trachea    6.875 Larval Carcass    1.875 Adult Head    0.9 Adult Eye    2.55 Adult Brain    4.1 Adult Thoracic-Abdominal Ganglion    2.7 Adult Crop    4 Adult Midgut    3.2 Adult Hindgut    1.3 Adult Malpighian Tubules    3.4 Adult Fat Body    6.4 Adult Salivary Gland    8.8 Adult Heart    2.3 Adult VirginFemale Spermatheca    4.8 Adult InseminatedFemale Spermatheca    9 Adult Ovary    1.1 Adult Testis    1189.7 Adult Male Accessory Gland    5.8 Adult Carcass    7.4 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    2.35 Larval Midgut    1.9 Larval Hindgut    2.3 Larval Malpighian Tubules    1.4 Larval Fat Body    103.7 Larval Salivary Gland    5.7 Larval Trachea    6.875 Larval Carcass    1.875 Adult Head    0.9 Adult Eye    2.55 Adult Brain    4.1 Adult Thoracic-Abdominal Ganglion    2.7 Adult Crop    4 Adult Midgut    3.2 Adult Hindgut    1.3 Adult Malpighian Tubules    3.4 Adult Fat Body    6.4 Adult Salivary Gland    8.8 Adult Heart    2.3 Adult VirginFemale Spermatheca    4.8 Adult InseminatedFemale Spermatheca    9 Adult Ovary    1.1 Adult Testis  (1189.7) Adult Male Accessory Gland    5.8 Adult Carcass    7.4 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    2.35 Larval Midgut    1.9 Larval Hindgut    2.3 Larval Malpighian Tubules    1.4 Larval Fat Body    103.7 Larval Salivary Gland    5.7 Larval Trachea    6.875 Larval Carcass    1.875 Adult Head    0.9 Adult Eye    2.55 Adult Brain    4.1 Adult Thoracic-Abdominal Ganglion    2.7 Adult Crop    4 Adult Midgut    3.2 Adult Hindgut    1.3 Adult Malpighian Tubules    3.4 Adult Fat Body    6.4 Adult Salivary Gland    8.8 Adult Heart    2.3 Adult VirginFemale Spermatheca    4.8 Adult InseminatedFemale Spermatheca    9 Adult Ovary    1.1 Adult Testis  1189.7 Adult Male Accessory Gland    5.8 Adult Carcass    7.4 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    2.35 Larval Midgut    1.9 Larval Hindgut    2.3 Larval Malpighian Tubules    1.4 Larval Fat Body    103.7 Larval Salivary Gland    5.7 Larval Trachea    6.875 Larval Carcass    1.875 Adult Head    0.9 Adult Eye    2.55 Adult Brain    4.1 Adult Thoracic-Abdominal Ganglion    2.7 Adult Crop    4 Adult Midgut    3.2 Adult Hindgut    1.3 Adult Malpighian Tubules    3.4 Adult Fat Body    6.4 Adult Salivary Gland    8.8 Adult Heart    2.3 Adult VirginFemale Spermatheca    4.8 Adult InseminatedFemale Spermatheca    9 Adult Ovary    1.1 Adult Testis    1189.7 Adult Male Accessory Gland    5.8 Adult Carcass    7.4 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    0.9   NA  Eye    2.55   NA  Brain    4.1   2.35  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    2.7   NA  Crop    4   1.9  Midgut    3.2   2.3  Hindgut    1.3   1.4  Malpighian Tubules    3.4   103.7  Fat Body    6.4   5.7  Salivary Gland    8.8   NA  Heart    2.3   6.875  Trachea    NA   NA  VirginFemale Spermatheca    4.8   NA  InseminatedFemale Spermatheca    9   NA  Ovary    1.1   NA  Testis    1189.7   NA  Male Accessory Gland    5.8   1.875  Carcass    7.4 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_33
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0036082 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG12362-RB
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal | pupal stage, with Scer\GAL4pnr-MD237 CG12362GD7583 Phenotype manifest in Allele
Classical Alleles ( 0 )
For All Classical Alleles Show
Allele of CG12362 Class Mutagen Stocks Known lesion
Alleles Carried on Transgenic Constructs ( 2 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG12362 Class Mutagen Stocks Known lesion CG12362GD7583 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes CG12362KK111335 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD7583} NA P{KK111335} NA
Insertions
	Type of insertions Name Expression data
Gene Ontology: Function, Process & Cellular Component ( 1 unique term )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 1 term )
Molecular Function
CV term Evidence References
zinc ion binding inferred from electronic annotation with InterPro:IPR001841, InterPro:IPR002867 (FlyBase Curators et al., 2004-)
Biological Process ( 0 terms)
Cellular Component ( 0 terms)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG12362 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 64574 DroID - A comprehensive database of gene and protein interactions. • FBgn0036082 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 39193
Orthologs
Genome-wide drosophilid orthologs	Dana\GF10593 Dere\GG15432 Dgri\GH14942 Dmoj\GI11465 Dpse\GA11583 Dsec\GM25208 Dvir\GJ13659 Dwil\GK24041 Dyak\GE21740
Curated drosophilid orthologs	Dpse\GA11583
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • At1g05890.1 Arabidopsis thaliana (wall cress) 100959 Chlamidomonas reinhardtii (green alga) DEHA2B01320g Debaryomyces Hansenii (yeast) XP_654228 Entamoeba histolytica (anaerobic protozoan) XP_655671 Entamoeba histolytica (anaerobic protozoan) LOC_Os03g13100.1 Oryza sativa (asian rice) PFC0175w Plasmodium falciparum (protozoal parasite) PVX_119315 Plasmodium vivax (protozoal parasite) 3828.m01418 Tetrahymena thermophila (ciliate protozoa) YALI0F27511g Yarrowia lipolytica (nonconventional yeast) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • FBgn0238986 FBgn0226003 FBgn0200880 FBgn0185923 FBgn0180068 FBgn0071634 FBgn0134226 FBgn0122417 FBgn0107683 FBgn0087634 GLEAN_02351
Stocks & Reagents
Stocks Listed in FlyBase ( 3 )
VDRC	v103218 P{KK111335}VIE-260B v31747 w1118 P{GD7583}v31747 v31746 w1118; P{GD7583}v31746/TM3
Genomic Clones ( 2 )
	BACR01K09 BACR05G01 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 14 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	AT17761
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT08701 AT14530 AT26165
Other clones	bs01e07 bs48e04 bs49b07 bs54h07 bs58h09 bs62c02 bs79f03 bs81c04 bs86d04 EC31548
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0036082 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 39193
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_140135 NM_168405 RefSeq (Proteins) • NP_648392 NP_729606 DDBJ / EMBL / GenBank • AAF50159 AAN11912 AAO39642 AI944449 BF502127 BT003638 Entrez Gene - A searchable database of RefSeq genes. • 39193 UniProtKB/TrEMBL • Q9VT94
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Zinc finger, RING-type (IPR001841) Zinc finger, C6HC-type (IPR002867) Zinc finger, RING/FYVE/PHD-type (IPR013083)
Linkouts
	BioGRID - A database of protein and genetic interactions • 64574 DroID - A comprehensive database of gene and protein interactions. • FBgn0036082 DRSC - Results from RNAi screens. • FBgn0036082 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0036082 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG12362-RB FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0036082 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 39193 InParanoid A subset of ortholog calls from InParanoid. • At1g05890.1 Arabidopsis thaliana (wall cress) 100959 Chlamidomonas reinhardtii (green alga) DEHA2B01320g Debaryomyces Hansenii (yeast) XP_654228 Entamoeba histolytica (anaerobic protozoan) XP_655671 Entamoeba histolytica (anaerobic protozoan) LOC_Os03g13100.1 Oryza sativa (asian rice) PFC0175w Plasmodium falciparum (protozoal parasite) PVX_119315 Plasmodium vivax (protozoal parasite) 3828.m01418 Tetrahymena thermophila (ciliate protozoa) YALI0F27511g Yarrowia lipolytica (nonconventional yeast) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 39193 modMine - Data generated by the modENCODE project. • FBgn0036082 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • FBgn0238986 FBgn0226003 FBgn0200880 FBgn0185923 FBgn0180068 FBgn0071634 FBgn0134226 FBgn0122417 FBgn0107683 FBgn0087634 GLEAN_02351
Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	CG12362 (Keleman et al., 2009.8.5, Luo et al., 2011)
Name Synonym
Secondary FlyBase IDs
References ( 14 )
Research paper	Luo et al., 2011, Development 138(13): 2761--2771 Direct targets of the D. melanogaster DSXF protein and the evolution of sexual development. [FBrf0213878] Lai et al., 2003, GenomeBiol. 4(7): R42 Computational identification of Drosophila microRNA genes. [FBrf0160711] Tseng and Hariharan, 2002, Genetics 162(1): 229--243 An overexpression screen in Drosophila for genes that restrict growth or cell-cycle progression in the developing eye. [FBrf0152035]
Supplementary material	The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518] Giot et al., 2003, Science 302(5651): Tables S1 to S7. [FBrf0166452]
Personal communication to FlyBase	Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] FlyBase Curators et al., 2004-, Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. [FBrf0174215] Oliver, 2001.8.16, File from B. Oliver containing information on ESTs expressed in the Drosophila testis, described in Andrews et al., 2000, Genome Res. 10(12): 2030-2043 (FBrf0132348). File from B. Oliver containing information on ESTs expressed in the Drosophila testis, described in Andrews et al., 2000, Genome Res. 10(12): 2030-2043 (FBrf0132348). [FBrf0137492]
FlyBase analysis	FlyBase, 1992-, FlyBase curation FlyBase curation. [FBrf0105495]
Computer file	BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. Berkeley Drosophila Genome Project. [FBrf0125078]
Automatic genome annotation	FamiliarityBreedsContempt, 1999.11, [Annotations performed at the Celera Jamboreee.] [Annotations performed at the Celera Jamboreee.] [FBrf0126705]