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Gene Dmel\Aps

General Information
Symbol	Dmel\Aps	Species	D. melanogaster
Name	Aps	Annotation symbol	CG6391
Feature type	protein_coding_gene	FlyBase ID	FBgn0036111
Gene Model Status	Current	Stock availability	8 publicly available
Genomic Location
Chromosome (arm)	3L	Recombination map
Cytogenetic map	67F1-67F1	Sequence location	3L:10,887,876..10,892,223 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene Aps is referred to in FlyBase by the symbol Dmel\Aps (CG6391, FBgn0036111). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: diphosphoinositol-polyphosphate diphosphatase activity. There is experimental evidence that it is involved in the biological process: inositol phosphate metabolic process; nucleotide metabolic process. 10 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. Protein features are: NUDIX hydrolase domain; NUDIX hydrolase domain-like; NUDIX hydrolase, conserved site. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression. Peak expression observed within 00-06 hour embryonic stages, in adult female stages. Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: larval central nervous system, adult crop, adult ovary, adult male accessory gland. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, adult central nervous system, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult spermathecae, adult testis, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1640329_s_at completely aligns to an exonic region common to each of the 3 FlyBase-annotated transcript isoforms of Aps. Gene sequence location is 3L:10887876..10892223.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 67F1-67F1   Limits computationally determined from genome sequence between P{lacW}tnaL6731 and P{PZ}klu09036
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\Aps for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.46 Low-frequency RNA-Seq exon junction(s) not annotated.
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) Aps-RA FBtr0076250  NM_140164   3115   177 Aps-RB FBtr0076251  NM_168425   2364   177 Aps-RC FBtr0076252  NM_168426   2744   177
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein Aps-PA   FBpp0075979   19.9   177   5.95     NP_648421   AAN11888 Aps-PB   FBpp0075980   19.9   177   5.95     NP_729639   AAF50123 Aps-PC   FBpp0075981   19.9   177   5.95     NP_729640   AAN11889
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • NUDIX hydrolase domain (IPR000086) NUDIX hydrolase domain-like (IPR015797) NUDIX hydrolase, conserved site (IPR020084)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA201271   AA201550   AA201636   AA201959   AA202769   AA247071   AA263462   AA263652   AA263672   AA263932   AA390459   AA390583   AA390611   AA391172   AA391405   AA391451   AA392848   AA440349   AA440596   AA536258   AA536568   AA539241   AA539904   AA539914   AA540627   AA567321   AA567600   AA821009   AA942365   AA949370   AA949945   AA951034   AA951110   AA952071   AA978467   AA978496   AA978548   AA978825   AA990633   AE014296 AAF50123   AE014296 AAN11888   AE014296 AAN11889   AI061956   AI293047   AI454956   AI454980   AI455691   AI512010   AI512017   AI512382   AI512391   AI512483   AI512680   AI513646   AI514676   AI514927   AI514955   AI515527   AI516710   AI517892   AI519543   AI534159   AI541652   AI543663   AJ863561 CAI10728   AJ863562 CAI10729   AJ863563 CAI10730   AJ863564 CAI10731   AX094142   AY118969 AAM50829   AZ877660   BF485518   BF503387   BG635420   BG637417   BG637766   BG638475   BG640298   BI162175   BI162176   BI163652   BI166771   BI168110   BI168552   BI170580   BI172903   BI212382   BI213299   BI214610   BI216106   BI216511   BI228179   BI231951   BI231993   BI236760   BI237915   BI240201   BI240341   BI243775   BI361982   BI362557   BI364825   BI366093   BI366421   BI367261   BI367324   BI368117   BI368275   BI370114   BI370187   BI373764   BI373826   BI375990   BI482566   BI482642   BI484157   BI484623   BI485411   BI486758   BI577286   BI578791   BI578842   BI582498   BI638466   BP540268   BP544907   BP546613   BP548366   BP553903   CK661350   CO154777   CO188372   CO191679   CO196204   CO196573   CO262807   CO265638   CO266542   CO270123   CO271456   CO271569   CO274309   CO277856   CO278778   CO279243   CO279336   CO282699   CO293103   CO293152   CO301754   CO304436   CO307043   CO309348   CO312556   CO313954   CO317209   CO322345   CO332480   CO336339   CO337435   CO339410   CO340168   CZ470659   CZ471632   CZ481290   CZ490213   EC052219   EC056727   EC061011   EC061038   EC072837   EC073060   EC076443   EC077479   EC078600   EC079039   EC082028   EC087761   EC202304   EC205142   EC212500   EC212546   EC220813   EC222953   EC223392   EC224932   EC225357   EC225723   EC226958   EC227561   EC243178   EC244597   EC245475   EC257862   EC259172   EC263801   EC265992   EC266996   EL884948   EL885455   EL885456   EV581633   EV592134   EV592297   EV594701   EV595464   EV598856   EV599991   EV600177   GH749327   GH753944   GH756522   GH758134   GH758603   GH770583   GH773478   GH776340   GH777328   GH777386   GH780509   GH782807   GH783583   GH788704   GH791822   GH797355   GH799225   GH799414   GH803378   GH804525   GH806988   GH811513   GH816062   GH816390   GH820890   GH825708   GH826598   GH826690   GH827352   GH828131   GH828728   GH830421   GH831802   GH832182   GH832243   GH832848   GH835658   GH836838   GH838273   GH842980   GH844022   GH846928   GH847127   GH853565   GH857277   GH859631   GH859754   GH861857   GH867399   GH867910   GH869042   GH870503   GH879958   GH884261   GH885747   GH893400   GH893711   GH893757   GH894759   GH899940   GH901189   GH903706   GH907415   GH908376   GH910060   GH911384   GH912482   GH913859   GH914451   GH916072   GH917730   GH918667   GH925671   GH926142   GH926504   GH930579   GH938533   GH941330   GH942101   GH942972   GH943078   GH943556   GH944068   GH944372   GH944747   GH945477   GH945893   GH945938   GH946231   GH946492   GH947284   GH948773   GH948940   GH950811   GH950899   GH951023   GH951736   GH951834   GH952374   GH952686   GH953059   GH953797   GH953991   GH954402   GH954440   GH954832   GH954853   GH955478   GH956323   GH956341   GH956859   GH957077   GH957504   GH957570   GH957694   GH957698   GH958034   GH958381   GH958687   GH961078   GH961462   GH962048   GH963380   GH963625   GH964262   GH964845   GH964866   GH964977   GH966006   GH966709   GH968845   GH969761   GH969792   GH970471   GH971146   GH971214   GH971943   GH973656   GH973707   GH974795   GH975097   GH976718   GH976751   GH976847   GH977032   GH977302   GH977447   GH977774   GH977960   GH977977   GH978207   GH979401   GH979736   GH980021   GH981500   GH982189   GH982441   GH983068   GH984572
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q7JVG2
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
in situ Stage Tissue/Position (including subcellular localization) Reference embryonic stage 1 -- 3   organism   (Fisher et al., 2012) Comment:maternally deposited embryonic stage 4 -- 6   organism   (Fisher et al., 2012) embryonic stage 7 -- 8   organism | ubiquitous   (Fisher et al., 2012) embryonic stage 9 -- 10   organism | ubiquitous   (Fisher et al., 2012) embryonic stage 11 -- 12   anterior midgut primordium   (Fisher et al., 2012) central brain primordium   (Fisher et al., 2012) embryonic neuroblast of ventral nerve cord primordium   (Fisher et al., 2012) foregut primordium   (Fisher et al., 2012) hindgut proper primordium   (Fisher et al., 2012) organism | ubiquitous   (Fisher et al., 2012) posterior midgut primordium   (Fisher et al., 2012) procephalic neuroblast   (Fisher et al., 2012) ventral nerve cord primordium   (Fisher et al., 2012) embryonic stage 13 -- 16   embryonic brain   (Fisher et al., 2012) embryonic central brain neuron   (Fisher et al., 2012) embryonic hindgut   (Fisher et al., 2012) embryonic Malpighian tubule   (Fisher et al., 2012) embryonic/larval midgut   (Fisher et al., 2012) organism | ubiquitous   (Fisher et al., 2012)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
cytoplasm inferred from direct assay (Winward et al., 2010) nucleus inferred from direct assay (Winward et al., 2010)
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: larval central nervous system, adult crop, adult ovary, adult male accessory gland. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, adult central nervous system, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult spermathecae, adult testis, larval/adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    627.625 Larval Midgut    320.5 Larval Hindgut    373.2 Larval Malpighian Tubules    403.8 Larval Fat Body    328.9 Larval Salivary Gland    303.4 Larval Trachea    441.275 Larval Carcass    343.3 Adult Head    315.2 Adult Eye    402.8 Adult Brain    386.9 Adult Thoracic-Abdominal Ganglion    395.1 Adult Crop    508.4 Adult Midgut    255.4 Adult Hindgut    351.4 Adult Malpighian Tubules    456.4 Adult Fat Body    301.8 Adult Salivary Gland    334.2 Adult Heart    216.675 Adult VirginFemale Spermatheca    218.7 Adult InseminatedFemale Spermatheca    220.4 Adult Ovary    857.4 Adult Testis    290.7 Adult Male Accessory Gland    507.3 Adult Carcass    214 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System  (627.625) Larval Midgut    320.5 Larval Hindgut    373.2 Larval Malpighian Tubules    403.8 Larval Fat Body    328.9 Larval Salivary Gland    303.4 Larval Trachea    441.275 Larval Carcass    343.3 Adult Head    315.2 Adult Eye    402.8 Adult Brain    386.9 Adult Thoracic-Abdominal Ganglion    395.1 Adult Crop  508.4 Adult Midgut    255.4 Adult Hindgut    351.4 Adult Malpighian Tubules    456.4 Adult Fat Body    301.8 Adult Salivary Gland    334.2 Adult Heart    216.675 Adult VirginFemale Spermatheca    218.7 Adult InseminatedFemale Spermatheca    220.4 Adult Ovary  (857.4) Adult Testis    290.7 Adult Male Accessory Gland  507.3 Adult Carcass    214 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    627.625 Larval Midgut    320.5 Larval Hindgut    373.2 Larval Malpighian Tubules    403.8 Larval Fat Body    328.9 Larval Salivary Gland    303.4 Larval Trachea    441.275 Larval Carcass    343.3 Adult Head    315.2 Adult Eye    402.8 Adult Brain    386.9 Adult Thoracic-Abdominal Ganglion    395.1 Adult Crop    508.4 Adult Midgut    255.4 Adult Hindgut    351.4 Adult Malpighian Tubules    456.4 Adult Fat Body    301.8 Adult Salivary Gland    334.2 Adult Heart    216.675 Adult VirginFemale Spermatheca    218.7 Adult InseminatedFemale Spermatheca    220.4 Adult Ovary    857.4 Adult Testis    290.7 Adult Male Accessory Gland    507.3 Adult Carcass    214 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    627.625 Larval Midgut    320.5 Larval Hindgut    373.2 Larval Malpighian Tubules    403.8 Larval Fat Body    328.9 Larval Salivary Gland    303.4 Larval Trachea    441.275 Larval Carcass    343.3 Adult Head    315.2 Adult Eye    402.8 Adult Brain    386.9 Adult Thoracic-Abdominal Ganglion    395.1 Adult Crop    508.4 Adult Midgut    255.4 Adult Hindgut    351.4 Adult Malpighian Tubules    456.4 Adult Fat Body    301.8 Adult Salivary Gland    334.2 Adult Heart    216.675 Adult VirginFemale Spermatheca    218.7 Adult InseminatedFemale Spermatheca    220.4 Adult Ovary    857.4 Adult Testis    290.7 Adult Male Accessory Gland    507.3 Adult Carcass    214 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    627.625 Larval Midgut    320.5 Larval Hindgut    373.2 Larval Malpighian Tubules    403.8 Larval Fat Body    328.9 Larval Salivary Gland    303.4 Larval Trachea    441.275 Larval Carcass    343.3 Adult Head    315.2 Adult Eye    402.8 Adult Brain    386.9 Adult Thoracic-Abdominal Ganglion    395.1 Adult Crop    508.4 Adult Midgut    255.4 Adult Hindgut    351.4 Adult Malpighian Tubules    456.4 Adult Fat Body    301.8 Adult Salivary Gland    334.2 Adult Heart    216.675 Adult VirginFemale Spermatheca    218.7 Adult InseminatedFemale Spermatheca    220.4 Adult Ovary    857.4 Adult Testis    290.7 Adult Male Accessory Gland    507.3 Adult Carcass    214 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System  627.625 Larval Midgut    320.5 Larval Hindgut    373.2 Larval Malpighian Tubules    403.8 Larval Fat Body    328.9 Larval Salivary Gland    303.4 Larval Trachea    441.275 Larval Carcass    343.3 Adult Head    315.2 Adult Eye    402.8 Adult Brain    386.9 Adult Thoracic-Abdominal Ganglion    395.1 Adult Crop  508.4 Adult Midgut    255.4 Adult Hindgut    351.4 Adult Malpighian Tubules    456.4 Adult Fat Body    301.8 Adult Salivary Gland    334.2 Adult Heart    216.675 Adult VirginFemale Spermatheca    218.7 Adult InseminatedFemale Spermatheca    220.4 Adult Ovary  (857.4) Adult Testis    290.7 Adult Male Accessory Gland  507.3 Adult Carcass    214 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    627.625 Larval Midgut    320.5 Larval Hindgut    373.2 Larval Malpighian Tubules    403.8 Larval Fat Body    328.9 Larval Salivary Gland    303.4 Larval Trachea    441.275 Larval Carcass    343.3 Adult Head    315.2 Adult Eye    402.8 Adult Brain    386.9 Adult Thoracic-Abdominal Ganglion    395.1 Adult Crop    508.4 Adult Midgut    255.4 Adult Hindgut    351.4 Adult Malpighian Tubules    456.4 Adult Fat Body    301.8 Adult Salivary Gland    334.2 Adult Heart    216.675 Adult VirginFemale Spermatheca    218.7 Adult InseminatedFemale Spermatheca    220.4 Adult Ovary    857.4 Adult Testis    290.7 Adult Male Accessory Gland    507.3 Adult Carcass    214 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    627.625 Larval Midgut    320.5 Larval Hindgut    373.2 Larval Malpighian Tubules    403.8 Larval Fat Body    328.9 Larval Salivary Gland    303.4 Larval Trachea    441.275 Larval Carcass    343.3 Adult Head    315.2 Adult Eye    402.8 Adult Brain    386.9 Adult Thoracic-Abdominal Ganglion    395.1 Adult Crop    508.4 Adult Midgut    255.4 Adult Hindgut    351.4 Adult Malpighian Tubules    456.4 Adult Fat Body    301.8 Adult Salivary Gland    334.2 Adult Heart    216.675 Adult VirginFemale Spermatheca    218.7 Adult InseminatedFemale Spermatheca    220.4 Adult Ovary    857.4 Adult Testis    290.7 Adult Male Accessory Gland    507.3 Adult Carcass    214 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    315.2   NA  Eye    402.8   NA  Brain    386.9   627.625  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    395.1   NA  Crop    508.4   320.5  Midgut    255.4   373.2  Hindgut    351.4   403.8  Malpighian Tubules    456.4   328.9  Fat Body    301.8   303.4  Salivary Gland    334.2   NA  Heart    216.675   441.275  Trachea    NA   NA  VirginFemale Spermatheca    218.7   NA  InseminatedFemale Spermatheca    220.4   NA  Ovary    857.4   NA  Testis    290.7   NA  Male Accessory Gland    507.3   343.3  Carcass    214 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    163 central nervous system, larvae L3    173 central nervous system, pupae P8    98 head, virgin 1-day female    76 head, virgin 4-day female    80 head, virgin 20-day female    37 head, mated 1-day female    79 head, mated 4-day female    65 head, mated 20-day female    44 head, mated 1-day male    89 head, mated 4-day male    97 head, mated 20-day male    89 salivary gland, larvae L3 wandering    35 salivary gland, white prepupae    254 digestive system, larvae L3 wandering    54 digestive system, 1-day adult    77 digestive system, 4-day adult    96 digestive system, 20-day adult    52 fat body, larvae L3 wandering    33 fat body, white prepupae    68 fat body, pupae P8    85 carcass, larvae L3 wandering    136 carcass, 1-day adult    75 carcass, 4-day adult    84 carcass, 20-day adult    62 ovary, virgin 4-day female    367 ovary, mated 4-day female    404 testis, mated 4-day male    63 accessory gland, mated 4-day male    45 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (163) central nervous system, larvae L3  (173) central nervous system, pupae P8  (98) head, virgin 1-day female  (76) head, virgin 4-day female  (80) head, virgin 20-day female  (37) head, mated 1-day female  (79) head, mated 4-day female  (65) head, mated 20-day female  (44) head, mated 1-day male  (89) head, mated 4-day male  (97) head, mated 20-day male  (89) salivary gland, larvae L3 wandering  (35) salivary gland, white prepupae  (254) digestive system, larvae L3 wandering  (54) digestive system, 1-day adult  (77) digestive system, 4-day adult  (96) digestive system, 20-day adult  (52) fat body, larvae L3 wandering  (33) fat body, white prepupae  (68) fat body, pupae P8  (85) carcass, larvae L3 wandering  (136) carcass, 1-day adult  (75) carcass, 4-day adult  (84) carcass, 20-day adult  (62) ovary, virgin 4-day female  (367) ovary, mated 4-day female  (404) testis, mated 4-day male  (63) accessory gland, mated 4-day male  (45) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (163) central nervous system, larvae L3  (173) central nervous system, pupae P8    98 head, virgin 1-day female    76 head, virgin 4-day female    80 head, virgin 20-day female    37 head, mated 1-day female    79 head, mated 4-day female    65 head, mated 20-day female    44 head, mated 1-day male    89 head, mated 4-day male    97 head, mated 20-day male    89 salivary gland, larvae L3 wandering    35 salivary gland, white prepupae  (254) digestive system, larvae L3 wandering    54 digestive system, 1-day adult    77 digestive system, 4-day adult    96 digestive system, 20-day adult    52 fat body, larvae L3 wandering    33 fat body, white prepupae    68 fat body, pupae P8    85 carcass, larvae L3 wandering  (136) carcass, 1-day adult    75 carcass, 4-day adult    84 carcass, 20-day adult    62 ovary, virgin 4-day female  (367) ovary, mated 4-day female  (404) testis, mated 4-day male    63 accessory gland, mated 4-day male    45 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    163 central nervous system, larvae L3    173 central nervous system, pupae P8    98 head, virgin 1-day female    76 head, virgin 4-day female    80 head, virgin 20-day female    37 head, mated 1-day female    79 head, mated 4-day female    65 head, mated 20-day female    44 head, mated 1-day male    89 head, mated 4-day male    97 head, mated 20-day male    89 salivary gland, larvae L3 wandering    35 salivary gland, white prepupae    254 digestive system, larvae L3 wandering    54 digestive system, 1-day adult    77 digestive system, 4-day adult    96 digestive system, 20-day adult    52 fat body, larvae L3 wandering    33 fat body, white prepupae    68 fat body, pupae P8    85 carcass, larvae L3 wandering    136 carcass, 1-day adult    75 carcass, 4-day adult    84 carcass, 20-day adult    62 ovary, virgin 4-day female    367 ovary, mated 4-day female    404 testis, mated 4-day male    63 accessory gland, mated 4-day male    45 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    163 central nervous system, larvae L3    173 central nervous system, pupae P8    98 head, virgin 1-day female    76 head, virgin 4-day female    80 head, virgin 20-day female    37 head, mated 1-day female    79 head, mated 4-day female    65 head, mated 20-day female    44 head, mated 1-day male    89 head, mated 4-day male    97 head, mated 20-day male    89 salivary gland, larvae L3 wandering    35 salivary gland, white prepupae    254 digestive system, larvae L3 wandering    54 digestive system, 1-day adult    77 digestive system, 4-day adult    96 digestive system, 20-day adult    52 fat body, larvae L3 wandering    33 fat body, white prepupae    68 fat body, pupae P8    85 carcass, larvae L3 wandering    136 carcass, 1-day adult    75 carcass, 4-day adult    84 carcass, 20-day adult    62 ovary, virgin 4-day female    367 ovary, mated 4-day female    404 testis, mated 4-day male    63 accessory gland, mated 4-day male    45 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (163) central nervous system, larvae L3  (173) central nervous system, pupae P8  (98) head, virgin 1-day female  (76) head, virgin 4-day female  (80) head, virgin 20-day female  (37) head, mated 1-day female  (79) head, mated 4-day female  (65) head, mated 20-day female  (44) head, mated 1-day male  (89) head, mated 4-day male  (97) head, mated 20-day male  (89) salivary gland, larvae L3 wandering  (35) salivary gland, white prepupae  (254) digestive system, larvae L3 wandering  (54) digestive system, 1-day adult  (77) digestive system, 4-day adult  (96) digestive system, 20-day adult  (52) fat body, larvae L3 wandering  (33) fat body, white prepupae  (68) fat body, pupae P8  (85) carcass, larvae L3 wandering  (136) carcass, 1-day adult  (75) carcass, 4-day adult  (84) carcass, 20-day adult  (62) ovary, virgin 4-day female  (367) ovary, mated 4-day female  (404) testis, mated 4-day male  (63) accessory gland, mated 4-day male  (45) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (163) central nervous system, larvae L3  (173) central nervous system, pupae P8    98 head, virgin 1-day female    76 head, virgin 4-day female    80 head, virgin 20-day female    37 head, mated 1-day female    79 head, mated 4-day female    65 head, mated 20-day female    44 head, mated 1-day male    89 head, mated 4-day male    97 head, mated 20-day male    89 salivary gland, larvae L3 wandering    35 salivary gland, white prepupae  (254) digestive system, larvae L3 wandering    54 digestive system, 1-day adult    77 digestive system, 4-day adult    96 digestive system, 20-day adult    52 fat body, larvae L3 wandering    33 fat body, white prepupae    68 fat body, pupae P8    85 carcass, larvae L3 wandering  136 carcass, 1-day adult    75 carcass, 4-day adult    84 carcass, 20-day adult    62 ovary, virgin 4-day female  (367) ovary, mated 4-day female  (404) testis, mated 4-day male    63 accessory gland, mated 4-day male    45 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    163 central nervous system, larvae L3    173 central nervous system, pupae P8    98 head, virgin 1-day female    76 head, virgin 4-day female    80 head, virgin 20-day female    37 head, mated 1-day female    79 head, mated 4-day female    65 head, mated 20-day female    44 head, mated 1-day male    89 head, mated 4-day male    97 head, mated 20-day male    89 salivary gland, larvae L3 wandering    35 salivary gland, white prepupae    254 digestive system, larvae L3 wandering    54 digestive system, 1-day adult    77 digestive system, 4-day adult    96 digestive system, 20-day adult    52 fat body, larvae L3 wandering    33 fat body, white prepupae    68 fat body, pupae P8    85 carcass, larvae L3 wandering    136 carcass, 1-day adult    75 carcass, 4-day adult    84 carcass, 20-day adult    62 ovary, virgin 4-day female    367 ovary, mated 4-day female    404 testis, mated 4-day male    63 accessory gland, mated 4-day male    45 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression. Peak expression observed within 00-06 hour embryonic stages, in adult female stages. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    150 embryo 02-04hr    246 embryo 04-06hr    187 embryo 06-08hr    54 embryo 08-10hr    79 embryo 10-12hr    83 embryo 12-14hr    86 embryo 14-16hr    73 embryo 16-18hr    64 embryo 18-20hr    32 embryo 20-22hr    70 embryo 22-24hr    77 larva L1    37 larva L2    38 larva L3 12hr old    30 larva L3 puffstage 1-2    30 larva L3 puffstage 3-6    50 larva L3 puffstage 7-9    74 white prepupae new    88 white prepupae 12hr    108 white prepupae 24hr    105 pupae 2d postWPP    81 pupae 3d postWPP    50 pupae 4d postWPP    30 adult male 01day    42 adult male 05day    40 adult male 30day    37 adult female 01day    72 adult female 05day    111 adult female 30day    105 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (150) embryo 02-04hr  (246) embryo 04-06hr  (187) embryo 06-08hr  (54) embryo 08-10hr  (79) embryo 10-12hr  (83) embryo 12-14hr  (86) embryo 14-16hr  (73) embryo 16-18hr  (64) embryo 18-20hr  (32) embryo 20-22hr  (70) embryo 22-24hr  (77) larva L1  (37) larva L2  (38) larva L3 12hr old  (30) larva L3 puffstage 1-2  (30) larva L3 puffstage 3-6  (50) larva L3 puffstage 7-9  (74) white prepupae new  (88) white prepupae 12hr  (108) white prepupae 24hr  (105) pupae 2d postWPP  (81) pupae 3d postWPP  (50) pupae 4d postWPP  (30) adult male 01day  (42) adult male 05day  (40) adult male 30day  (37) adult female 01day  (72) adult female 05day  (111) adult female 30day  (105) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr  (150) embryo 02-04hr  (246) embryo 04-06hr  (187) embryo 06-08hr    54 embryo 08-10hr    79 embryo 10-12hr    83 embryo 12-14hr    86 embryo 14-16hr    73 embryo 16-18hr    64 embryo 18-20hr    32 embryo 20-22hr    70 embryo 22-24hr    77 larva L1    37 larva L2    38 larva L3 12hr old    30 larva L3 puffstage 1-2    30 larva L3 puffstage 3-6    50 larva L3 puffstage 7-9    74 white prepupae new    88 white prepupae 12hr  (108) white prepupae 24hr  105 pupae 2d postWPP    81 pupae 3d postWPP    50 pupae 4d postWPP    30 adult male 01day    42 adult male 05day    40 adult male 30day    37 adult female 01day    72 adult female 05day  (111) adult female 30day  105 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    150 embryo 02-04hr    246 embryo 04-06hr    187 embryo 06-08hr    54 embryo 08-10hr    79 embryo 10-12hr    83 embryo 12-14hr    86 embryo 14-16hr    73 embryo 16-18hr    64 embryo 18-20hr    32 embryo 20-22hr    70 embryo 22-24hr    77 larva L1    37 larva L2    38 larva L3 12hr old    30 larva L3 puffstage 1-2    30 larva L3 puffstage 3-6    50 larva L3 puffstage 7-9    74 white prepupae new    88 white prepupae 12hr    108 white prepupae 24hr    105 pupae 2d postWPP    81 pupae 3d postWPP    50 pupae 4d postWPP    30 adult male 01day    42 adult male 05day    40 adult male 30day    37 adult female 01day    72 adult female 05day    111 adult female 30day    105 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    150 embryo 02-04hr    246 embryo 04-06hr    187 embryo 06-08hr    54 embryo 08-10hr    79 embryo 10-12hr    83 embryo 12-14hr    86 embryo 14-16hr    73 embryo 16-18hr    64 embryo 18-20hr    32 embryo 20-22hr    70 embryo 22-24hr    77 larva L1    37 larva L2    38 larva L3 12hr old    30 larva L3 puffstage 1-2    30 larva L3 puffstage 3-6    50 larva L3 puffstage 7-9    74 white prepupae new    88 white prepupae 12hr    108 white prepupae 24hr    105 pupae 2d postWPP    81 pupae 3d postWPP    50 pupae 4d postWPP    30 adult male 01day    42 adult male 05day    40 adult male 30day    37 adult female 01day    72 adult female 05day    111 adult female 30day    105 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (150) embryo 02-04hr  (246) embryo 04-06hr  (187) embryo 06-08hr  (54) embryo 08-10hr  (79) embryo 10-12hr  (83) embryo 12-14hr  (86) embryo 14-16hr  (73) embryo 16-18hr  (64) embryo 18-20hr  32 embryo 20-22hr  (70) embryo 22-24hr  (77) larva L1  (37) larva L2  (38) larva L3 12hr old  30 larva L3 puffstage 1-2  30 larva L3 puffstage 3-6  (50) larva L3 puffstage 7-9  (74) white prepupae new  (88) white prepupae 12hr  (108) white prepupae 24hr  (105) pupae 2d postWPP  (81) pupae 3d postWPP  (50) pupae 4d postWPP  30 adult male 01day  (42) adult male 05day  (40) adult male 30day  (37) adult female 01day  (72) adult female 05day  (111) adult female 30day  (105) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr  (150) embryo 02-04hr  (246) embryo 04-06hr  (187) embryo 06-08hr    54 embryo 08-10hr    79 embryo 10-12hr    83 embryo 12-14hr    86 embryo 14-16hr    73 embryo 16-18hr    64 embryo 18-20hr    32 embryo 20-22hr    70 embryo 22-24hr    77 larva L1    37 larva L2    38 larva L3 12hr old    30 larva L3 puffstage 1-2    30 larva L3 puffstage 3-6    50 larva L3 puffstage 7-9    74 white prepupae new    88 white prepupae 12hr  108 white prepupae 24hr  105 pupae 2d postWPP    81 pupae 3d postWPP    50 pupae 4d postWPP    30 adult male 01day    42 adult male 05day    40 adult male 30day    37 adult female 01day    72 adult female 05day  111 adult female 30day  105 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    150 embryo 02-04hr    246 embryo 04-06hr    187 embryo 06-08hr    54 embryo 08-10hr    79 embryo 10-12hr    83 embryo 12-14hr    86 embryo 14-16hr    73 embryo 16-18hr    64 embryo 18-20hr    32 embryo 20-22hr    70 embryo 22-24hr    77 larva L1    37 larva L2    38 larva L3 12hr old    30 larva L3 puffstage 1-2    30 larva L3 puffstage 3-6    50 larva L3 puffstage 7-9    74 white prepupae new    88 white prepupae 12hr    108 white prepupae 24hr    105 pupae 2d postWPP    81 pupae 3d postWPP    50 pupae 4d postWPP    30 adult male 01day    42 adult male 05day    40 adult male 30day    37 adult female 01day    72 adult female 05day    111 adult female 30day    105 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    129 Schneider line 2 Sg4    166 embryonic 1182-4H    172 embryonic GM2    173 embryonic Kc167    180 embryonic S1    119 embryonic S3    265 leg disc CME L1    134 wing disc CME-W2    214 wing disc ML-DmD8    244 wing disc ML-DmD9    157 wing disc ML-DmD16-c3    156 wing disc ML-DmD21    153 wing disc ML-DmD32    168 haltere disc ML-DmD17-c3    135 eye-antennal disc ML-DmD11    138 antennal disc ML-DmD20-c5    93 mixed discs ML-DmD4-c1    143 CNS ML-DmBG1-c1    152 CNS ML-DmBG2-c2    95 tumorous blood cells mbn2    120 ovary fGS/OSS    207 ovary OSC    360 ovary OSS    205 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (129) Schneider line 2 Sg4  (166) embryonic 1182-4H  (172) embryonic GM2  (173) embryonic Kc167  (180) embryonic S1  (119) embryonic S3  (265) leg disc CME L1  (134) wing disc CME-W2  (214) wing disc ML-DmD8  (244) wing disc ML-DmD9  (157) wing disc ML-DmD16-c3  (156) wing disc ML-DmD21  (153) wing disc ML-DmD32  (168) haltere disc ML-DmD17-c3  (135) eye-antennal disc ML-DmD11  (138) antennal disc ML-DmD20-c5  (93) mixed discs ML-DmD4-c1  (143) CNS ML-DmBG1-c1  (152) CNS ML-DmBG2-c2  (95) tumorous blood cells mbn2  (120) ovary fGS/OSS  (207) ovary OSC  (360) ovary OSS  (205) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+  (129) Schneider line 2 Sg4  (166) embryonic 1182-4H  (172) embryonic GM2  (173) embryonic Kc167  (180) embryonic S1  (119) embryonic S3  (265) leg disc CME L1  (134) wing disc CME-W2  (214) wing disc ML-DmD8  (244) wing disc ML-DmD9  (157) wing disc ML-DmD16-c3  (156) wing disc ML-DmD21  (153) wing disc ML-DmD32  (168) haltere disc ML-DmD17-c3  (135) eye-antennal disc ML-DmD11  (138) antennal disc ML-DmD20-c5    93 mixed discs ML-DmD4-c1  (143) CNS ML-DmBG1-c1  (152) CNS ML-DmBG2-c2    95 tumorous blood cells mbn2  (120) ovary fGS/OSS  (207) ovary OSC  (360) ovary OSS  (205) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    129 Schneider line 2 Sg4    166 embryonic 1182-4H    172 embryonic GM2    173 embryonic Kc167    180 embryonic S1    119 embryonic S3    265 leg disc CME L1    134 wing disc CME-W2    214 wing disc ML-DmD8    244 wing disc ML-DmD9    157 wing disc ML-DmD16-c3    156 wing disc ML-DmD21    153 wing disc ML-DmD32    168 haltere disc ML-DmD17-c3    135 eye-antennal disc ML-DmD11    138 antennal disc ML-DmD20-c5    93 mixed discs ML-DmD4-c1    143 CNS ML-DmBG1-c1    152 CNS ML-DmBG2-c2    95 tumorous blood cells mbn2    120 ovary fGS/OSS    207 ovary OSC    360 ovary OSS    205 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    129 Schneider line 2 Sg4    166 embryonic 1182-4H    172 embryonic GM2    173 embryonic Kc167    180 embryonic S1    119 embryonic S3    265 leg disc CME L1    134 wing disc CME-W2    214 wing disc ML-DmD8    244 wing disc ML-DmD9    157 wing disc ML-DmD16-c3    156 wing disc ML-DmD21    153 wing disc ML-DmD32    168 haltere disc ML-DmD17-c3    135 eye-antennal disc ML-DmD11    138 antennal disc ML-DmD20-c5    93 mixed discs ML-DmD4-c1    143 CNS ML-DmBG1-c1    152 CNS ML-DmBG2-c2    95 tumorous blood cells mbn2    120 ovary fGS/OSS    207 ovary OSC    360 ovary OSS    205 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (129) Schneider line 2 Sg4  (166) embryonic 1182-4H  (172) embryonic GM2  (173) embryonic Kc167  (180) embryonic S1  (119) embryonic S3  (265) leg disc CME L1  (134) wing disc CME-W2  (214) wing disc ML-DmD8  (244) wing disc ML-DmD9  (157) wing disc ML-DmD16-c3  (156) wing disc ML-DmD21  (153) wing disc ML-DmD32  (168) haltere disc ML-DmD17-c3  (135) eye-antennal disc ML-DmD11  (138) antennal disc ML-DmD20-c5  (93) mixed discs ML-DmD4-c1  (143) CNS ML-DmBG1-c1  (152) CNS ML-DmBG2-c2  (95) tumorous blood cells mbn2  (120) ovary fGS/OSS  (207) ovary OSC  (360) ovary OSS  (205) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+  129 Schneider line 2 Sg4  (166) embryonic 1182-4H  (172) embryonic GM2  (173) embryonic Kc167  (180) embryonic S1  119 embryonic S3  (265) leg disc CME L1  134 wing disc CME-W2  (214) wing disc ML-DmD8  (244) wing disc ML-DmD9  (157) wing disc ML-DmD16-c3  (156) wing disc ML-DmD21  (153) wing disc ML-DmD32  (168) haltere disc ML-DmD17-c3  135 eye-antennal disc ML-DmD11  138 antennal disc ML-DmD20-c5    93 mixed discs ML-DmD4-c1  143 CNS ML-DmBG1-c1  (152) CNS ML-DmBG2-c2    95 tumorous blood cells mbn2  120 ovary fGS/OSS  (207) ovary OSC  (360) ovary OSS  (205) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    129 Schneider line 2 Sg4    166 embryonic 1182-4H    172 embryonic GM2    173 embryonic Kc167    180 embryonic S1    119 embryonic S3    265 leg disc CME L1    134 wing disc CME-W2    214 wing disc ML-DmD8    244 wing disc ML-DmD9    157 wing disc ML-DmD16-c3    156 wing disc ML-DmD21    153 wing disc ML-DmD32    168 haltere disc ML-DmD17-c3    135 eye-antennal disc ML-DmD11    138 antennal disc ML-DmD20-c5    93 mixed discs ML-DmD4-c1    143 CNS ML-DmBG1-c1    152 CNS ML-DmBG2-c2    95 tumorous blood cells mbn2    120 ovary fGS/OSS    207 ovary OSC    360 ovary OSS    205 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    140 cold shock, 4-day adult    101 heat shock, 4-day adult    105 Cadmium 50 mM 6 hrs, larvae L3    45 Cadmium 50 mM 12 hrs, larvae L3    73 Cadmium 50 mM 48 hrs, 4-day adult    132 Cadmium 100 mM 48 hrs, 4-day adult    302 Copper 0.5 mM 12 hrs, larvae L3    77 Copper 15 mM 48 hrs, 4-day adult    441 Zinc 5 mM 12 hrs, larvae L3    77 Zinc 4.5 mM 48 hrs, 4-day adult    190 Ethanol 2.5% 3 hrs, larvae L3    147 Ethanol 5% 3 hrs, larvae L3    54 Ethanol 10% 3 hrs, larvae L3    38 Caffeine 1.5 mg/ml 4 hrs, larvae L3    41 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    269 Caffeine 25 mg/ml 48 hrs, 4-day adult    163 Paraquat 5 mM 48 hrs, 4-day adult    204 Paraquat 10 mM 48 hrs, 4-day adult    117 Rotenone 2 μg 12 hrs, larvae L3    46 Rotenone 8 μg 12 hrs, larvae L3    27 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult  (140) cold shock, 4-day adult  (101) heat shock, 4-day adult  (105) Cadmium 50 mM 6 hrs, larvae L3  (45) Cadmium 50 mM 12 hrs, larvae L3  (73) Cadmium 50 mM 48 hrs, 4-day adult  (132) Cadmium 100 mM 48 hrs, 4-day adult  (302) Copper 0.5 mM 12 hrs, larvae L3  (77) Copper 15 mM 48 hrs, 4-day adult  (441) Zinc 5 mM 12 hrs, larvae L3  (77) Zinc 4.5 mM 48 hrs, 4-day adult  (190) Ethanol 2.5% 3 hrs, larvae L3  (147) Ethanol 5% 3 hrs, larvae L3  (54) Ethanol 10% 3 hrs, larvae L3  (38) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (41) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (269) Caffeine 25 mg/ml 48 hrs, 4-day adult  (163) Paraquat 5 mM 48 hrs, 4-day adult  (204) Paraquat 10 mM 48 hrs, 4-day adult  (117) Rotenone 2 μg 12 hrs, larvae L3  (46) Rotenone 8 μg 12 hrs, larvae L3  (27) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult  (140) cold shock, 4-day adult  101 heat shock, 4-day adult  105 Cadmium 50 mM 6 hrs, larvae L3    45 Cadmium 50 mM 12 hrs, larvae L3    73 Cadmium 50 mM 48 hrs, 4-day adult  (132) Cadmium 100 mM 48 hrs, 4-day adult  (302) Copper 0.5 mM 12 hrs, larvae L3    77 Copper 15 mM 48 hrs, 4-day adult  (441) Zinc 5 mM 12 hrs, larvae L3    77 Zinc 4.5 mM 48 hrs, 4-day adult  (190) Ethanol 2.5% 3 hrs, larvae L3  (147) Ethanol 5% 3 hrs, larvae L3    54 Ethanol 10% 3 hrs, larvae L3    38 Caffeine 1.5 mg/ml 4 hrs, larvae L3    41 Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (269) Caffeine 25 mg/ml 48 hrs, 4-day adult  (163) Paraquat 5 mM 48 hrs, 4-day adult  (204) Paraquat 10 mM 48 hrs, 4-day adult  (117) Rotenone 2 μg 12 hrs, larvae L3    46 Rotenone 8 μg 12 hrs, larvae L3    27 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    140 cold shock, 4-day adult    101 heat shock, 4-day adult    105 Cadmium 50 mM 6 hrs, larvae L3    45 Cadmium 50 mM 12 hrs, larvae L3    73 Cadmium 50 mM 48 hrs, 4-day adult    132 Cadmium 100 mM 48 hrs, 4-day adult    302 Copper 0.5 mM 12 hrs, larvae L3    77 Copper 15 mM 48 hrs, 4-day adult    441 Zinc 5 mM 12 hrs, larvae L3    77 Zinc 4.5 mM 48 hrs, 4-day adult    190 Ethanol 2.5% 3 hrs, larvae L3    147 Ethanol 5% 3 hrs, larvae L3    54 Ethanol 10% 3 hrs, larvae L3    38 Caffeine 1.5 mg/ml 4 hrs, larvae L3    41 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    269 Caffeine 25 mg/ml 48 hrs, 4-day adult    163 Paraquat 5 mM 48 hrs, 4-day adult    204 Paraquat 10 mM 48 hrs, 4-day adult    117 Rotenone 2 μg 12 hrs, larvae L3    46 Rotenone 8 μg 12 hrs, larvae L3    27 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    140 cold shock, 4-day adult    101 heat shock, 4-day adult    105 Cadmium 50 mM 6 hrs, larvae L3    45 Cadmium 50 mM 12 hrs, larvae L3    73 Cadmium 50 mM 48 hrs, 4-day adult    132 Cadmium 100 mM 48 hrs, 4-day adult    302 Copper 0.5 mM 12 hrs, larvae L3    77 Copper 15 mM 48 hrs, 4-day adult    441 Zinc 5 mM 12 hrs, larvae L3    77 Zinc 4.5 mM 48 hrs, 4-day adult    190 Ethanol 2.5% 3 hrs, larvae L3    147 Ethanol 5% 3 hrs, larvae L3    54 Ethanol 10% 3 hrs, larvae L3    38 Caffeine 1.5 mg/ml 4 hrs, larvae L3    41 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    269 Caffeine 25 mg/ml 48 hrs, 4-day adult    163 Paraquat 5 mM 48 hrs, 4-day adult    204 Paraquat 10 mM 48 hrs, 4-day adult    117 Rotenone 2 μg 12 hrs, larvae L3    46 Rotenone 8 μg 12 hrs, larvae L3    27 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult  (140) cold shock, 4-day adult  (101) heat shock, 4-day adult  (105) Cadmium 50 mM 6 hrs, larvae L3  (45) Cadmium 50 mM 12 hrs, larvae L3  (73) Cadmium 50 mM 48 hrs, 4-day adult  (132) Cadmium 100 mM 48 hrs, 4-day adult  (302) Copper 0.5 mM 12 hrs, larvae L3  (77) Copper 15 mM 48 hrs, 4-day adult  (441) Zinc 5 mM 12 hrs, larvae L3  (77) Zinc 4.5 mM 48 hrs, 4-day adult  (190) Ethanol 2.5% 3 hrs, larvae L3  (147) Ethanol 5% 3 hrs, larvae L3  (54) Ethanol 10% 3 hrs, larvae L3  (38) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (41) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (269) Caffeine 25 mg/ml 48 hrs, 4-day adult  (163) Paraquat 5 mM 48 hrs, 4-day adult  (204) Paraquat 10 mM 48 hrs, 4-day adult  (117) Rotenone 2 μg 12 hrs, larvae L3  (46) Rotenone 8 μg 12 hrs, larvae L3  27 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult  140 cold shock, 4-day adult  101 heat shock, 4-day adult  105 Cadmium 50 mM 6 hrs, larvae L3    45 Cadmium 50 mM 12 hrs, larvae L3    73 Cadmium 50 mM 48 hrs, 4-day adult  132 Cadmium 100 mM 48 hrs, 4-day adult  (302) Copper 0.5 mM 12 hrs, larvae L3    77 Copper 15 mM 48 hrs, 4-day adult  (441) Zinc 5 mM 12 hrs, larvae L3    77 Zinc 4.5 mM 48 hrs, 4-day adult  (190) Ethanol 2.5% 3 hrs, larvae L3  (147) Ethanol 5% 3 hrs, larvae L3    54 Ethanol 10% 3 hrs, larvae L3    38 Caffeine 1.5 mg/ml 4 hrs, larvae L3    41 Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (269) Caffeine 25 mg/ml 48 hrs, 4-day adult  (163) Paraquat 5 mM 48 hrs, 4-day adult  (204) Paraquat 10 mM 48 hrs, 4-day adult  117 Rotenone 2 μg 12 hrs, larvae L3    46 Rotenone 8 μg 12 hrs, larvae L3    27 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    140 cold shock, 4-day adult    101 heat shock, 4-day adult    105 Cadmium 50 mM 6 hrs, larvae L3    45 Cadmium 50 mM 12 hrs, larvae L3    73 Cadmium 50 mM 48 hrs, 4-day adult    132 Cadmium 100 mM 48 hrs, 4-day adult    302 Copper 0.5 mM 12 hrs, larvae L3    77 Copper 15 mM 48 hrs, 4-day adult    441 Zinc 5 mM 12 hrs, larvae L3    77 Zinc 4.5 mM 48 hrs, 4-day adult    190 Ethanol 2.5% 3 hrs, larvae L3    147 Ethanol 5% 3 hrs, larvae L3    54 Ethanol 10% 3 hrs, larvae L3    38 Caffeine 1.5 mg/ml 4 hrs, larvae L3    41 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    269 Caffeine 25 mg/ml 48 hrs, 4-day adult    163 Paraquat 5 mM 48 hrs, 4-day adult    204 Paraquat 10 mM 48 hrs, 4-day adult    117 Rotenone 2 μg 12 hrs, larvae L3    46 Rotenone 8 μg 12 hrs, larvae L3    27 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_01 mE1_20_mRNA_expression_cluster_10
External Data & Images
Linkouts	BDGP expression data • LD46602 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0036111 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG6391-RA FlyExpress - Embryonic expression images (BDGP data) • Show all FlyExpress processed images for Aps Stages(s) 4-6 Stages(s) 7-8 Stages(s) 9-10 Stages(s) 11-12 Stages(s) 13-16
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable, with Scer\GAL4pnr-MD237 ApsGD10570 Phenotype manifest in Allele
Classical Alleles ( 6 )
For All Classical Alleles Show
Allele of Aps Class Mutagen Stocks Known lesion ApsBG00831 P-element activity 1 -- Apsc06396 piggyBac transposase 1 -- Apsd00496 P-element activity 1 -- Apse03524 piggyBac transposase 1 -- Apsf07457 piggyBac transposase 1 -- ApsNP0150 1 --
Alleles Carried on Transgenic Constructs ( 4 )
For All Alleles Carried on Transgenic Constructs Show
Allele of Aps Class Mutagen Stocks Known lesion ApsGD10570 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes ApsKK108331 in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes ApsKK109021 in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes ApsNIG.6391R in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD10570} NA P{KK108331} NA P{KK109021} NA P{NIG.6391R} NA
Insertions
	Type of insertions Name Expression data miscellaneous insertions P{GT1}ApsBG00831 NA PBac{PB}Apsc06396 NA PBac{RB}Apse03524 NA PBac{WH}Apsf07457 NA insertion of enhancer trap binary system P{GawB}ApsNP0150 No insertion of mobile activating element P{XP}Apsd00496 NA
Gene Ontology: Function, Process & Cellular Component ( 5 unique terms )
Terms Based on Experimental Evidence ( 5 terms )
Molecular Function
CV term Evidence References
diphosphoinositol-polyphosphate diphosphatase activity inferred from direct assay (Winward et al., 2010)
Biological Process
CV term Evidence References
inositol phosphate metabolic process inferred from direct assay (Winward et al., 2010) nucleotide metabolic process inferred from direct assay (Winward et al., 2010)
Cellular Component
CV term Evidence References
cytoplasm inferred from direct assay (Winward et al., 2010) nucleus inferred from direct assay (Winward et al., 2010)
Terms Based on Predictions or Assertions ( 1 term )
Molecular Function
CV term Evidence References
diphosphoinositol-polyphosphate diphosphatase activity inferred from sequence or structural similarity with EMBL:AF062529 (FlyBase, 1992-)
Biological Process ( 0 terms)
Cellular Component ( 0 terms)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions Aps allele Gene References
External Data
Linkouts	DroID - A comprehensive database of gene and protein interactions. • FBgn0036111 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 39226
Orthologs
OrthoDB Orthologs (50) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG61C7GR Dipteran inclusive ortholog search EOG6CJVSF Insect inclusive ortholog search EOG6N5TTH Arthropod inclusive ortholog search EOG6RN8S1 Metazoa inclusive ortholog search EOG6F81F8
Orthologs in Drosophila Species (EOG61C7GR)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\Aps     Drosophila simulans   Dsim\GD17584 Y   Drosophila sechellia   Dsec\GM24794 Y   Drosophila erecta   Dere\GG13955 Y   Drosophila yakuba   Dyak\GE20253 Y   Drosophila ananassae   Dana\GF23815 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA19558 Y   Drosophila persimilis   Dper\GL11750 Y   Drosophila willistoni   Dwil\GK18021 Y   Drosophila virilis   Dvir\GJ11730 Y   Drosophila mojavensis   Dmoj\GI13875 Y   Drosophila grimshawi   Dgri\GH16579 Y
Orthologs in non-Drosophila Dipterans (EOG6CJVSF)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL003678   Anopheles gambiae Malaria mosquito  Agam\AGAP009901   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ801809
Orthologs in non-Dipteran Insects (EOG6N5TTH)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\Aps   Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG012341   Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH14067   Atta cephalotes Leafcutter ant  Acep\ACEP13322   Camponotus floridanus Florida carpenter ant  Cflo\CFLO22880   Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL22128   Linepithema humile Argentine ant  Lhum\LH11396   Pogonomyrmex barbatus Red harvester ant  Pbar\PB12376   Solenopsis invicta Red fire ant  Sinv\SINV24308   Acyrthosiphon pisum Pea aphid  Apim\ACYPI002733   Bombyx mori Silkmoth  Bmor\BGIBMGA011973   Pediculus humanus Human body louse  Phum\PHUM041410   Tribolium castaneum Red flour beetle  Tcas\TC003674
Orthologs in non-Insect Arthropods (EOG6RN8S1)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\TMEM27   Ixodes scapularis Deer tick  Isca\ISCW020460
Orthologs in non-Arthropod Metazoa (EOG6F81F8)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Caenorhabditis elegans Nematode  Cele\Y92H12BL.5   Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_020851gn   Danio rerio Zebrafish  Drer\nudt3b   Danio rerio Zebrafish  Drer\nudt4b   Danio rerio Zebrafish  Drer\nudt3a   Danio rerio Zebrafish  Drer\nudt4a   Xenopus tropicalis Western clawed frog  Xtro\nudt4   Gallus gallus Domestic chicken  Ggal\NUDT3   Gallus gallus Domestic chicken  Ggal\NUDT4   Mus musculus House mouse  Mmus\Nudt11   Mus musculus House mouse  Mmus\Nudt4   Mus musculus House mouse  Mmus\Nudt11   Rattus norvegicus Norway rat  Rnor\Nudt11   Rattus norvegicus Norway rat  Rnor\Nudt4   Rattus norvegicus Norway rat  Rnor\Nudt3   Rattus norvegicus Norway rat  Rnor\Nudt11   Homo sapiens Human  Hsap\NUDT10   Homo sapiens Human  Hsap\NUDT3   Homo sapiens Human  Hsap\NUDT11   Homo sapiens Human  Hsap\ENSG00000173598
Human Orthologs (4)
Gene OMIM HGNC Hsap\NUDT10     Hsap\NUDT3     Hsap\NUDT11     Hsap\ENSG00000173598
AAA Orthologs (11) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD17584 Drosophila sechellia Dsec\GM24794 Drosophila erecta Dere\GG13955 Drosophila yakuba Dyak\GE20253 Drosophila ananassae Dana\GF23815 Drosophila pseudoobscura pseudoobscura Dpse\GA19558 Drosophila persimilis Dper\GL11750 Drosophila willistoni Dwil\GK18021 Drosophila virilis Dvir\GJ11730 Drosophila mojavensis Dmoj\GI13875 Drosophila grimshawi Dgri\GH16579
Stocks & Reagents
Stocks Listed in FlyBase ( 8 )
Bloomington	12439 w1118; P{GT1}ApsBG00831
Harvard	- P{XP}Apsd00496 - PBac{PB}Apsc06396 - PBac{RB}Apse03524 - PBac{WH}Apsf07457
Kyoto	103540 y* w*; P{GawB}ApsNP0150 / TM6, P{UAS-lacZ.UW23-1}UW23-1
VDRC	v25995 w1118; P{GD10570}v25995 v25996 w1118; P{GD10570}v25996
Genomic Clones ( 1 )
	BACR02C14 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 354 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones
Other clones	LD21193 LD46602 SD06690 SD07826
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT19360 AT19503 GH16125 HL01039 HL01516 LD01231 LD04296 LD04373 LD04702 LD05048 LD05093 LD06853 LD06913 LD07195 LD07283 LD09248 LD09335 LD09604 LD09605 LD10292 LD10514 LD12032 LD14925 LD15426 LD16757 LD17328 LD18916 LD19202 LD19214 LD20377 LD24988 LD26432 LD26522 LD28241 LD28519 LD29115 LD30665 LD30727 LD31208 LD31304 LD31410 LD33001 LD34432 LD35063 LD35334 LD39170 LD41162 LD42691 LD43029 LD43615 LD43626 LD44244 LD44256 LD44371 LD44622 LD45852 LD46561 LP20789 RE03103 RE08661 RE09325 RE12088 RE15604 RE17466 RE18670 RE20570 RE23024 RE23661 RE25135 RE25183 RE25633 RE32870 RE34247 RE36894 RE37167 RE46429 RE47150 RE50013 RE51543 RE51955 RE52980 RE53066 RE54033 RE54221 RE56520 RE56616 RE61167 RE61250 RE63909 RE65271 RE65357 RE67215 RE67753 RE68730 RE70222 RE70946 RE72717 RE72772 RH20719 SD05914 SD06678 SD10533 SD11282 SD12828 SD15420 SD20759
Other clones	10713 15590 16175 20068 32753 35965 45308 54864 60912 72541 73180 83360 102513 102683 103190 104522 107932 147760 163072 177101 177602 194027 214347.33 214575.24 273300 524110 557760 569105 CK01.102D.E5 CK01.112D.F1 CK01.127B.B4 Dmel_dig_009980_0645_1390 Dmel_neb_012569_0577_1784 Dmel_neb_012629_0876_1760 Dmel_neb_014037_0701_1167 Dmel_neb_014119_0699_0693 Dmel_neb_014572_0911_0560 Dmel_neb_014688_0700_0908 Dmel_neb_015545_0889_2231 EC31658 EC052219 EK001923 EK006008 EK039421 EK086419 EK097429 EK103512 EK103912 EK113753 EK127046 EK131547 EK133859 EK134103 EK143251 EK146810 EK161010 EK182107 EK187935 EK201718 EK201935 EK217411 EK229263 EK234357 EK244707 EK253346 EK267335 EK303606 EN04761 EN12332 EN14540 EP01932 EP10135 FGA001F09 FGC028D11 FGH108C06 FGH127A07 FGM226H09 IP16153 IP16844 LD01861 LD03053 LD47394 RE01564 RE06987 RE41506 RP003020013 RP003023297 RP003032168 RP003039276 RP003044538 RP003051074 RP003071607 RP003093034 RP003104680 RP003110256 RP003128071 RP003131211 RP003141574 RP003143453 RP003157734 RP003165910 RP003173126 RP003178045 RP003178475 RP003182305 RP003187682 RP003190955 RP003214222 RP003215029 RP003216367 RP003221968 RP003230776 RP003232713 RP003233950 RP003241265 RP003243400 RP003243993 RP003266162 RP003270345 RP003275623 RP003276149 RP003283846 RP003288703 RP003300440 RP003306785 RP003310497 RP003318729 RP003333449 RP003336054 RP003336998 RP003344474 RP003348957 RP003363380 RP003368730 RP003387019 RP003391330 RP003401986 RP003409632 RP003411947 RP003452773 RP003454024 RP003459655 RP003464548 RP003485499 RP003488113 RP003492930 RP003503518 RP003505892 RP003570482 RP003595451 RP003599538 RP003610020 RP003614844 RP003616818 RP003618239 RP003618689 RP003623836 RP003625657 RP003628574 RP003632966 RP003649205 RP003677628 RP004026502 RP004035150 RP004044401 RP004053127 RP004053165 RP004055581 RP004058132 RP004066101 RP004069782 RP004080707 RP004081427 RP004096799 RP004107450 RP004108152 RP004114222 RP004114999 RP004120802 RP004124538 RP004137041 RP004140881 RP004145035 RP004152818 RP004154374 RP004162512 RP004163647 RP004164011 RP004189626 RP004194355 RP004196735 RP004211174 RP004214844 RP004219325 RP004221317 RP004221565 RP004223887 RP004224445 RP004226308 RP004230036 RP004231340 RP004237582 RP004242123 RP004243734 RP004245238 RP004246321 RP004250088 RP004251174 RP004251941 RP004256563 RP004259401 RP004262816 RP004265404 RP004265721 RP004267339 RP004279118 RP004290658 RP004297243 RP004304250 RP004309102 RP004311667 RP004312006 RP004349928 RP004356264 RP004377308 RP004378217 RP004404744 RP004415899 RP004416882 RP004426836 RP004436628 RP004437330 RP004449211 RP004477086 RP004485372 RP004496182 RP004498454 RP004499302 RP004507492 RP004513330 RP004515069 RP004529823 RP004535282 RP004540036
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0036111 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 39226
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of	Source for identity of: Aps CG6391 (Safrany, 2004.11.15)
Source for database merge of	Source for merge of: Aps anon-WO0118547.266 (FlyBase, 1996-)
Additional comments	Source for merge of Aps anon-WO0118547.266 was sequence comparison (date:051113). (FlyBase, 1996-)
Other Comments
	Area matching Drosophila ESTs AA539914 and AA201959 (1042bp contig). (Davies, 2001.3.15)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_140164 NM_168425 NM_168426 RefSeq (Proteins) • NP_648421 NP_729639 NP_729640 DDBJ / EMBL / GenBank • AA201959 AA539914 AAF50123 AAM50829 AAN11888 AAN11889 AI514955 AJ863561 AJ863562 AJ863563 AJ863564 AX094142 AY118969 AZ877660 CAI10728 CAI10729 CAI10730 CAI10731 CZ470659 CZ471632 CZ481290 CZ490213 Entrez Gene - A searchable database of RefSeq genes. • 39226 UniProtKB/TrEMBL • Q7JVG2
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • NUDIX hydrolase domain (IPR000086) NUDIX hydrolase domain-like (IPR015797) NUDIX hydrolase, conserved site (IPR020084) BDGP expression data - Patterns of gene expression in Drosophila embryogenesis • LD46602
Linkouts
	DroID - A comprehensive database of gene and protein interactions. • FBgn0036111 DRSC - Results from RNAi screens. • FBgn0036111 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0036111 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG6391-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0036111 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 39226 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 39226 modMine - Data generated by the modENCODE project. • FBgn0036111
Synonyms & Secondary IDs ( 3 )
Reported As
Symbol Synonym	anon-WO0118547.266   Aps (Winward et al., 2010, Japanese National Institute of Genetics, 2012.5.21) CG6391 (Winward et al., 2010, Keleman et al., 2009.8.5)
Name Synonym	Aps
Secondary FlyBase IDs
	FBgn0062133
References ( 21 )
Generate a list of	All references relating to this gene ( 21 )
List References by type	Research paper  ( 1 ) Supplementary material  ( 3 ) Personal communication to FlyBase  ( 5 ) FlyBase analysis  ( 3 ) Stock list  ( 1 ) DNA/RNA sequence record  ( 5 ) Patent  ( 1 ) Website  ( 1 ) Curated genome annotation  ( 1 )
Recent research papers (0)
	All research papers listed in FlyBase were published before 2011 Show research papers ...