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Gene Dmel\RpL10Ab

General Information
Symbol	Dmel\RpL10Ab	Species	D. melanogaster
Name	Ribosomal protein L10Ab	Annotation symbol	CG7283
Feature type	protein_coding_gene	FlyBase ID	FBgn0036213
Gene Model Status	Current	Stock availability	10 publicly available
Genomic Location
Chromosome (arm)	3L	Recombination map
Cytogenetic map	68E1-68E1	Sequence location	3L:11,815,951..11,817,311 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene Ribosomal protein L10Ab is referred to in FlyBase by the symbol Dmel\RpL10Ab (CG7283, FBgn0036213). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: structural constituent of ribosome. There is experimental evidence that it is involved in the biological process: mitotic spindle elongation; mitotic spindle organization; centrosome duplication. 10 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. Protein features are: Ribosomal protein L1; Ribosomal protein L1, 2-layer alpha/beta-sandwich; Ribosomal protein L1, 3-layer alpha/beta-sandwich; Ribosomal protein L1, superfamily. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of extremely high expression to a trough of very high expression. Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, during early pupal stages, in adult female stages. Summary of FlyAtlas Anatomical Expression Data: High levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male reproductive system, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1638570_a_at completely aligns to an exonic region common to each of the 2 FlyBase-annotated transcript isoforms of RpL10Ab. Gene sequence location is 3L:11815951..11817311.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 68E1-68E1   Limits computationally determined from genome sequence between P{PZ}l(3)0123901239&P{lacW}l(3)01239j9B4 and P{PZ}CycA02461&P{PZ}CycA03946
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\RpL10Ab for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.45 short CDS OK Low-frequency RNA-seq exon junction(s) not annotated.
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) RpL10Ab-RA FBtr0076032  NM_140257   750   217 RpL10Ab-RD FBtr0302135  NM_168481   960   155 RpL10Ab-RE FBtr0304648  NM_001259794   801   155
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein RpL10Ab-PA   FBpp0075764   24.3   217   10.58     NP_648514   AAF50002 RpL10Ab-PD   FBpp0291345   17.3   155   10.44     NP_729754   AAN12245 RpL10Ab-PE   FBpp0293190   17.3   155   10.44     NP_001246723   AFH04394
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Ribosomal protein L1 (IPR002143) Ribosomal protein L1, 3-layer alpha/beta-sandwich (IPR016095) Ribosomal protein L1, 2-layer alpha/beta-sandwich (IPR016094) Ribosomal protein L1, superfamily (IPR023674)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA202512   AA246965   AA438860   AA440188   AA694879   AA695458   AA696603   AA696817   AA696954   AA697218   AA735312   AA735383   AA735540   AA801697   AA802158   AA803484   AA803729   AA803825   AA804102   AA820227   AA821015   AA821163   AA941992   AE014296 AAF50002   AE014296 AAN12245   AF083291   AE014296 AFH04394   AI062178   AI106808   AI107450   AI107685   AI107692   AI108235   AI109170   AI109331   AI134474   AI237959   AI238022   AI238437   AI239067   AI293897   AI294028   AI294762   AI388435   AI389070   AI403037   AI405609   AI405899   AI455847   AI512592   AI515485   AI518634   AI518682   AI519857   AI533705   AI534240   AI534962   AI945300   AY231773   AY232031   AY431736   AY440221   AY826152   BF489920   BF496412   BG634493   BG636005   BG636013   BG636317   BG637556   BG640868   BI141896   BI141992   BI161825   BI161969   BI162068   BI162796   BI162824   BI164726   BI164911   BI165646   BI166023   BI166610   BI167923   BI168382   BI168878   BI169757   BI170028   BI170777   BI171048   BI171144   BI171662   BI172250   BI172367   BI173415   BI173893   BI213321   BI213476   BI213586   BI214825   BI215460   BI227654   BI228122   BI228858   BI229512   BI229962   BI230322   BI231607   BI231938   BI232386   BI232853   BI233321   BI234991   BI235260   BI236377   BI236388   BI236639   BI236682   BI237879   BI238159   BI238732   BI239417   BI241515   BI242228   BI242334   BI242624   BI242914   BI243021   BI351908   BI352176   BI352450   BI352607   BI353156   BI353189   BI353201   BI353276   BI353526   BI354459   BI354814   BI355502   BI355629   BI356005   BI356025   BI356178   BI357212   BI357279   BI357575   BI357903   BI361941   BI362206   BI362464   BI362805   BI363728   BI364681   BI366026   BI366629   BI368976   BI369546   BI371279   BI371485   BI371692   BI373464   BI373660   BI373792   BI374152   BI374917   BI374950   BI375804   BI376016   BI376032   BI481569   BI482178   BI482389   BI483271   BI483745   BI484529   BI486103   BI486741   BI486813   BI487041   BI564568   BI567979   BI572069   BI576930   BI578106   BI579238   BI579388   BI579721   BI579995   BI580451   BI580630   BI588318   BI591616   BI605144   BI608866   BI613278   BI613849   BI613899   BI614099   BI614198   BI614500   BI622548   BI626987   BI627835   BI629557   BI630813   BP540323   BP540603   BP540755   BP541285   BP541590   BP541756   BP542549   BP542610   BP542686   BP542888   BP542906   BP543338   BP543352   BP543560   BP543624   BP543896   BP543953   BP544066   BP544320   BP544575   BP544649   BP544885   BP545010   BP545115   BP545173   BP545234   BP545862   BP545928   BP545942   BP545997   BP546048   BP546130   BP546136   BP546163   BP546247   BP546310   BP546335   BP546378   BP546382   BP546517   BP546519   BP546807   BP546827   BP546837   BP546844   BP546932   BP547003   BP547013   BP547040   BP547225   BP547377   BP547403   BP547419   BP547546   BP547655   BP547690   BP547691   BP547763   BP548239   BP548280   BP548556   BP548558   BP548582   BP548619   BP549606   BP549954   BP550208   BP550357   BP550399   BP552656   BP553122   BP553989   BP554343   BP554977   BP555036   BP555066   BP555812   BP556239   BP556624   BP556705   BP557127   BP557181   BP557780   BP557828   BP558016   BP558110   BP558849   BP559193   BP559730   BP559805   BP560075   BP560150   BP560214   BP560267   BQ102692   BQ102844   BT001758 AAN71513   BT001825 AAN71580   BT014654   BX005993   BX006372   BX006433   BX006478   BX006993   BX008303   BX008488   BX008490   BX008969   BX009130   BX009270   BX009418   BX010075   BX010508   BX011349   BX011638   BX012013   BX012429   BX012549   BX013671   BX013841   BX013965   BX014526   BX015555   BX015662   BX016563   BX016880   BX016888   BX016894   BX017048   BX018282   BX018330   BX018503   BX018565   BX019180   BX019212   BX020541   BX020783   BX021508   BX021977   BX023066   BX023271   BX023518   BX023968   BX024289   BX024449   BX024799   BX025488   BX026139   BX026524   BX026798   BX027261   BX027295   BX027539   BX027588   BX028136   BX028644   BX028677   BX029425   BX029558   BX029639   BX029766   BX030212   BX030458   BX031103   BX031650   BX032600   BX033185   BX033510   BX034638   BX035712   BX035850   BX036036   BX037610   BX037773   BX038197   BX038342   BX038463   BX038775   BX038847   BX039003   BX040428   BX042360   BX042625   BX042920   BX042924   BX043302   BX043382   BX043474   BX044463   BX045382   BX045438   BX045468   BX045492   BX046234   BX047410   BX047422   BX047485   BX048699   BX048882   BX050435   BX050570   BX050785   BX053561   BX053954   BX055434   BX056303   BX056669   BX057964   BX059022   BX059288   BX059681   BX060981   BX061888   BX062332   BX062610   BX063711   BX064039   BX064406   BX065428   BX065461   BX066665   BX067033   BX068764   BX069267   BX069580   BX070613   BX070707   BX071755   BZ665670   CA806577   CA807533   CK604472   CK604567   CK604568   CK605318   CK605319   CK656979   CK657435   CK658102   CK658148   CK658280   CK658302   CK658303   CK658626   CK658738   CK660126   CO153015   CO153614   CO154180   CO154691   CO154801   CO155221   CO179944   CO180317   CO180463   CO180954   CO181668   CO183372   CO183685   CO183723   CO184392   CO184830   CO188934   CO191259   CO193985   CO194781   CO195100   CO195515   CO195628   CO195647   CO273739   CO285617   CO288909   CO289566   CO295413   CO297199   CO309188   CO335560   CO337954   CO338751   CR937988   CR938383   CR938414   CR938654   CR938665   CZ468858   CZ468859   DQ440101   DQ675547   EC060547   EC062338   EC080591   EC195374   EC201423   EC201863   EC207651   EC211228   EC219845   EC236130   EC261816   EC261938   EC262820   EC263146   EC263614   EC263745   EC263804   EC266017   EC266877   EC267069   EC267163   EC267465   EL869702   EL875531   EV575763   EV576411   EV576448   EV576481   EV577139   EV577270   EV577309   EV578078   EV578316   EV580861   EV581271   EV581654   EV582481   EV582497   EV582995   EV583299   EV584449   EV584681   EV584795   EV584836   EV585163   EV585181   EV585201   EV585542   EV585776   EV586154   EV586529   EV587028   EV589996   EV590314   EV592788   EV593403   EV593567   EV593769   EV595296   EV595430   EV595900   EV596013   EV596463   EV596843   EV597688   EV598181   EV599205   EV599467   GH750389   GH751313   GH752144   GH754429   GH759012   GH760303   GH770266   GH770954   GH771880   GH772082   GH772874   GH773053   GH774070   GH777976   GH780194   GH781938   GH782465   GH783776   GH787153   GH787741   GH791331   GH791382   GH793922   GH794377   GH795223   GH800959   GH801583   GH801712   GH806552   GH807673   GH808514   GH809431   GH810195   GH811794   GH812790   GH813181   GH815282   GH817019   GH817221   GH819232   GH820962   GH821775   GH823989   GH824215   GH827323   GH827471   GH828098   GH830186   GH834167   GH835293   GH835802   GH837759   GH846090   GH847180   GH847312   GH848402   GH849970   GH851352   GH851535   GH854462   GH855759   GH856476   GH858745   GH858788   GH861958   GH864635   GH865887   GH866689   GH872686   GH873070   GH874940   GH875536   GH876756   GH879129   GH879292   GH879815   GH884598   GH884850   GH885381   GH885610   GH885782   GH889250   GH889789   GH890948   GH893145   GH899451   GH901914   GH901957   GH903923   GH904126   GH908552   GH911618   GH915050   GH917113   GH917307   GH919898   GH922002   GH922509   GH922674   GH923014   GH928833   GH929285   GH930531   GH930962   GH932239   GH933425   GH937162   GH938132   GH938228
UniProtKB/Swiss-Prot	Q9VTP4
UniProtKB/TrEMBL	Q8IGE1 Q8IGJ3
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
mass spectroscopy Stage Tissue/Position (including subcellular localization) Reference day 7 of adulthood -- day 49 of adulthood   adult heart   (Cammarato et al., 2011)
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: High levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male reproductive system, larval/adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    2495.525 Larval Midgut    4468.1 Larval Hindgut    3999.8 Larval Malpighian Tubules    4466.2 Larval Fat Body    6387.3 Larval Salivary Gland    7176.1 Larval Trachea    5288.575 Larval Carcass    4389.975 Adult Head    4117.9 Adult Eye    5916.625 Adult Brain    2475.1 Adult Thoracic-Abdominal Ganglion    3614.3 Adult Crop    5351.6 Adult Midgut    4837.7 Adult Hindgut    4571.2 Adult Malpighian Tubules    5304.8 Adult Fat Body    5218.7 Adult Salivary Gland    9091.6 Adult Heart    5961.325 Adult VirginFemale Spermatheca    5259.3 Adult InseminatedFemale Spermatheca    5436.4 Adult Ovary    3014.6 Adult Testis    1277.8 Adult Male Accessory Gland    8263.8 Adult Carcass    5271 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System  (2495.525) Larval Midgut  (4468.1) Larval Hindgut  (3999.8) Larval Malpighian Tubules  (4466.2) Larval Fat Body  (6387.3) Larval Salivary Gland  (7176.1) Larval Trachea  (5288.575) Larval Carcass  (4389.975) Adult Head  (4117.9) Adult Eye  (5916.625) Adult Brain  (2475.1) Adult Thoracic-Abdominal Ganglion  (3614.3) Adult Crop  (5351.6) Adult Midgut  (4837.7) Adult Hindgut  (4571.2) Adult Malpighian Tubules  (5304.8) Adult Fat Body  (5218.7) Adult Salivary Gland  (9091.6) Adult Heart  (5961.325) Adult VirginFemale Spermatheca  (5259.3) Adult InseminatedFemale Spermatheca  (5436.4) Adult Ovary  (3014.6) Adult Testis  (1277.8) Adult Male Accessory Gland  (8263.8) Adult Carcass  (5271) Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System  (2495.525) Larval Midgut  (4468.1) Larval Hindgut  (3999.8) Larval Malpighian Tubules  (4466.2) Larval Fat Body  (6387.3) Larval Salivary Gland  (7176.1) Larval Trachea  (5288.575) Larval Carcass  (4389.975) Adult Head  (4117.9) Adult Eye  (5916.625) Adult Brain  (2475.1) Adult Thoracic-Abdominal Ganglion  (3614.3) Adult Crop  (5351.6) Adult Midgut  (4837.7) Adult Hindgut  (4571.2) Adult Malpighian Tubules  (5304.8) Adult Fat Body  (5218.7) Adult Salivary Gland  (9091.6) Adult Heart  (5961.325) Adult VirginFemale Spermatheca  (5259.3) Adult InseminatedFemale Spermatheca  (5436.4) Adult Ovary  (3014.6) Adult Testis  (1277.8) Adult Male Accessory Gland  (8263.8) Adult Carcass  (5271) Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    2495.525 Larval Midgut    4468.1 Larval Hindgut    3999.8 Larval Malpighian Tubules    4466.2 Larval Fat Body    6387.3 Larval Salivary Gland    7176.1 Larval Trachea    5288.575 Larval Carcass    4389.975 Adult Head    4117.9 Adult Eye    5916.625 Adult Brain    2475.1 Adult Thoracic-Abdominal Ganglion    3614.3 Adult Crop    5351.6 Adult Midgut    4837.7 Adult Hindgut    4571.2 Adult Malpighian Tubules    5304.8 Adult Fat Body    5218.7 Adult Salivary Gland    9091.6 Adult Heart    5961.325 Adult VirginFemale Spermatheca    5259.3 Adult InseminatedFemale Spermatheca    5436.4 Adult Ovary    3014.6 Adult Testis    1277.8 Adult Male Accessory Gland    8263.8 Adult Carcass    5271 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    2495.525 Larval Midgut    4468.1 Larval Hindgut    3999.8 Larval Malpighian Tubules    4466.2 Larval Fat Body    6387.3 Larval Salivary Gland    7176.1 Larval Trachea    5288.575 Larval Carcass    4389.975 Adult Head    4117.9 Adult Eye    5916.625 Adult Brain    2475.1 Adult Thoracic-Abdominal Ganglion    3614.3 Adult Crop    5351.6 Adult Midgut    4837.7 Adult Hindgut    4571.2 Adult Malpighian Tubules    5304.8 Adult Fat Body    5218.7 Adult Salivary Gland    9091.6 Adult Heart    5961.325 Adult VirginFemale Spermatheca    5259.3 Adult InseminatedFemale Spermatheca    5436.4 Adult Ovary    3014.6 Adult Testis    1277.8 Adult Male Accessory Gland    8263.8 Adult Carcass    5271 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System  (2495.525) Larval Midgut  (4468.1) Larval Hindgut  (3999.8) Larval Malpighian Tubules  (4466.2) Larval Fat Body  (6387.3) Larval Salivary Gland  (7176.1) Larval Trachea  (5288.575) Larval Carcass  (4389.975) Adult Head  (4117.9) Adult Eye  (5916.625) Adult Brain  (2475.1) Adult Thoracic-Abdominal Ganglion  (3614.3) Adult Crop  (5351.6) Adult Midgut  (4837.7) Adult Hindgut  (4571.2) Adult Malpighian Tubules  (5304.8) Adult Fat Body  (5218.7) Adult Salivary Gland  (9091.6) Adult Heart  (5961.325) Adult VirginFemale Spermatheca  (5259.3) Adult InseminatedFemale Spermatheca  (5436.4) Adult Ovary  (3014.6) Adult Testis  (1277.8) Adult Male Accessory Gland  (8263.8) Adult Carcass  (5271) Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System  (2495.525) Larval Midgut  (4468.1) Larval Hindgut  (3999.8) Larval Malpighian Tubules  (4466.2) Larval Fat Body  (6387.3) Larval Salivary Gland  (7176.1) Larval Trachea  (5288.575) Larval Carcass  (4389.975) Adult Head  (4117.9) Adult Eye  (5916.625) Adult Brain  (2475.1) Adult Thoracic-Abdominal Ganglion  (3614.3) Adult Crop  (5351.6) Adult Midgut  (4837.7) Adult Hindgut  (4571.2) Adult Malpighian Tubules  (5304.8) Adult Fat Body  (5218.7) Adult Salivary Gland  (9091.6) Adult Heart  (5961.325) Adult VirginFemale Spermatheca  (5259.3) Adult InseminatedFemale Spermatheca  (5436.4) Adult Ovary  (3014.6) Adult Testis  1277.8 Adult Male Accessory Gland  (8263.8) Adult Carcass  (5271) Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    2495.525 Larval Midgut    4468.1 Larval Hindgut    3999.8 Larval Malpighian Tubules    4466.2 Larval Fat Body    6387.3 Larval Salivary Gland    7176.1 Larval Trachea    5288.575 Larval Carcass    4389.975 Adult Head    4117.9 Adult Eye    5916.625 Adult Brain    2475.1 Adult Thoracic-Abdominal Ganglion    3614.3 Adult Crop    5351.6 Adult Midgut    4837.7 Adult Hindgut    4571.2 Adult Malpighian Tubules    5304.8 Adult Fat Body    5218.7 Adult Salivary Gland    9091.6 Adult Heart    5961.325 Adult VirginFemale Spermatheca    5259.3 Adult InseminatedFemale Spermatheca    5436.4 Adult Ovary    3014.6 Adult Testis    1277.8 Adult Male Accessory Gland    8263.8 Adult Carcass    5271 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    4117.9   NA  Eye    5916.625   NA  Brain    2475.1   2495.525  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    3614.3   NA  Crop    5351.6   4468.1  Midgut    4837.7   3999.8  Hindgut    4571.2   4466.2  Malpighian Tubules    5304.8   6387.3  Fat Body    5218.7   7176.1  Salivary Gland    9091.6   NA  Heart    5961.325   5288.575  Trachea    NA   NA  VirginFemale Spermatheca    5259.3   NA  InseminatedFemale Spermatheca    5436.4   NA  Ovary    3014.6   NA  Testis    1277.8   NA  Male Accessory Gland    8263.8   4389.975  Carcass    5271 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    713 central nervous system, larvae L3    686 central nervous system, pupae P8    350 head, virgin 1-day female    400 head, virgin 4-day female    591 head, virgin 20-day female    845 head, mated 1-day female    390 head, mated 4-day female    698 head, mated 20-day female    630 head, mated 1-day male    372 head, mated 4-day male    413 head, mated 20-day male    683 salivary gland, larvae L3 wandering    485 salivary gland, white prepupae    1191 digestive system, larvae L3 wandering    645 digestive system, 1-day adult    673 digestive system, 4-day adult    520 digestive system, 20-day adult    590 fat body, larvae L3 wandering    416 fat body, white prepupae    390 fat body, pupae P8    832 carcass, larvae L3 wandering    869 carcass, 1-day adult    404 carcass, 4-day adult    479 carcass, 20-day adult    507 ovary, virgin 4-day female    599 ovary, mated 4-day female    519 testis, mated 4-day male    706 accessory gland, mated 4-day male    574 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (713) central nervous system, larvae L3  (686) central nervous system, pupae P8  (350) head, virgin 1-day female  (400) head, virgin 4-day female  (591) head, virgin 20-day female  (845) head, mated 1-day female  (390) head, mated 4-day female  (698) head, mated 20-day female  (630) head, mated 1-day male  (372) head, mated 4-day male  (413) head, mated 20-day male  (683) salivary gland, larvae L3 wandering  (485) salivary gland, white prepupae  (1191) digestive system, larvae L3 wandering  (645) digestive system, 1-day adult  (673) digestive system, 4-day adult  (520) digestive system, 20-day adult  (590) fat body, larvae L3 wandering  (416) fat body, white prepupae  (390) fat body, pupae P8  (832) carcass, larvae L3 wandering  (869) carcass, 1-day adult  (404) carcass, 4-day adult  (479) carcass, 20-day adult  (507) ovary, virgin 4-day female  (599) ovary, mated 4-day female  (519) testis, mated 4-day male  (706) accessory gland, mated 4-day male  (574) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (713) central nervous system, larvae L3  (686) central nervous system, pupae P8  (350) head, virgin 1-day female  (400) head, virgin 4-day female  (591) head, virgin 20-day female  (845) head, mated 1-day female  (390) head, mated 4-day female  (698) head, mated 20-day female  (630) head, mated 1-day male  (372) head, mated 4-day male  (413) head, mated 20-day male  (683) salivary gland, larvae L3 wandering  (485) salivary gland, white prepupae  (1191) digestive system, larvae L3 wandering  (645) digestive system, 1-day adult  (673) digestive system, 4-day adult  (520) digestive system, 20-day adult  (590) fat body, larvae L3 wandering  (416) fat body, white prepupae  (390) fat body, pupae P8  (832) carcass, larvae L3 wandering  (869) carcass, 1-day adult  (404) carcass, 4-day adult  (479) carcass, 20-day adult  (507) ovary, virgin 4-day female  (599) ovary, mated 4-day female  (519) testis, mated 4-day male  (706) accessory gland, mated 4-day male  (574) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    713 central nervous system, larvae L3    686 central nervous system, pupae P8    350 head, virgin 1-day female    400 head, virgin 4-day female    591 head, virgin 20-day female    845 head, mated 1-day female    390 head, mated 4-day female    698 head, mated 20-day female    630 head, mated 1-day male    372 head, mated 4-day male    413 head, mated 20-day male    683 salivary gland, larvae L3 wandering    485 salivary gland, white prepupae    1191 digestive system, larvae L3 wandering    645 digestive system, 1-day adult    673 digestive system, 4-day adult    520 digestive system, 20-day adult    590 fat body, larvae L3 wandering    416 fat body, white prepupae    390 fat body, pupae P8    832 carcass, larvae L3 wandering    869 carcass, 1-day adult    404 carcass, 4-day adult    479 carcass, 20-day adult    507 ovary, virgin 4-day female    599 ovary, mated 4-day female    519 testis, mated 4-day male    706 accessory gland, mated 4-day male    574 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    713 central nervous system, larvae L3    686 central nervous system, pupae P8    350 head, virgin 1-day female    400 head, virgin 4-day female    591 head, virgin 20-day female    845 head, mated 1-day female    390 head, mated 4-day female    698 head, mated 20-day female    630 head, mated 1-day male    372 head, mated 4-day male    413 head, mated 20-day male    683 salivary gland, larvae L3 wandering    485 salivary gland, white prepupae    1191 digestive system, larvae L3 wandering    645 digestive system, 1-day adult    673 digestive system, 4-day adult    520 digestive system, 20-day adult    590 fat body, larvae L3 wandering    416 fat body, white prepupae    390 fat body, pupae P8    832 carcass, larvae L3 wandering    869 carcass, 1-day adult    404 carcass, 4-day adult    479 carcass, 20-day adult    507 ovary, virgin 4-day female    599 ovary, mated 4-day female    519 testis, mated 4-day male    706 accessory gland, mated 4-day male    574 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (713) central nervous system, larvae L3  (686) central nervous system, pupae P8  (350) head, virgin 1-day female  (400) head, virgin 4-day female  (591) head, virgin 20-day female  (845) head, mated 1-day female  (390) head, mated 4-day female  (698) head, mated 20-day female  (630) head, mated 1-day male  (372) head, mated 4-day male  (413) head, mated 20-day male  (683) salivary gland, larvae L3 wandering  (485) salivary gland, white prepupae  (1191) digestive system, larvae L3 wandering  (645) digestive system, 1-day adult  (673) digestive system, 4-day adult  (520) digestive system, 20-day adult  (590) fat body, larvae L3 wandering  (416) fat body, white prepupae  (390) fat body, pupae P8  (832) carcass, larvae L3 wandering  (869) carcass, 1-day adult  (404) carcass, 4-day adult  (479) carcass, 20-day adult  (507) ovary, virgin 4-day female  (599) ovary, mated 4-day female  (519) testis, mated 4-day male  (706) accessory gland, mated 4-day male  (574) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (713) central nervous system, larvae L3  (686) central nervous system, pupae P8  (350) head, virgin 1-day female  (400) head, virgin 4-day female  (591) head, virgin 20-day female  (845) head, mated 1-day female  (390) head, mated 4-day female  (698) head, mated 20-day female  (630) head, mated 1-day male  (372) head, mated 4-day male  (413) head, mated 20-day male  (683) salivary gland, larvae L3 wandering  (485) salivary gland, white prepupae  (1191) digestive system, larvae L3 wandering  (645) digestive system, 1-day adult  (673) digestive system, 4-day adult  (520) digestive system, 20-day adult  (590) fat body, larvae L3 wandering  (416) fat body, white prepupae  (390) fat body, pupae P8  (832) carcass, larvae L3 wandering  (869) carcass, 1-day adult  (404) carcass, 4-day adult  (479) carcass, 20-day adult  (507) ovary, virgin 4-day female  (599) ovary, mated 4-day female  (519) testis, mated 4-day male  (706) accessory gland, mated 4-day male  (574) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    713 central nervous system, larvae L3    686 central nervous system, pupae P8    350 head, virgin 1-day female    400 head, virgin 4-day female    591 head, virgin 20-day female    845 head, mated 1-day female    390 head, mated 4-day female    698 head, mated 20-day female    630 head, mated 1-day male    372 head, mated 4-day male    413 head, mated 20-day male    683 salivary gland, larvae L3 wandering    485 salivary gland, white prepupae    1191 digestive system, larvae L3 wandering    645 digestive system, 1-day adult    673 digestive system, 4-day adult    520 digestive system, 20-day adult    590 fat body, larvae L3 wandering    416 fat body, white prepupae    390 fat body, pupae P8    832 carcass, larvae L3 wandering    869 carcass, 1-day adult    404 carcass, 4-day adult    479 carcass, 20-day adult    507 ovary, virgin 4-day female    599 ovary, mated 4-day female    519 testis, mated 4-day male    706 accessory gland, mated 4-day male    574 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of extremely high expression to a trough of very high expression. Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, during early pupal stages, in adult female stages. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    1030 embryo 02-04hr    1809 embryo 04-06hr    2108 embryo 06-08hr    2198 embryo 08-10hr    2471 embryo 10-12hr    2808 embryo 12-14hr    1950 embryo 14-16hr    2202 embryo 16-18hr    1929 embryo 18-20hr    1934 embryo 20-22hr    2361 embryo 22-24hr    2252 larva L1    2511 larva L2    2241 larva L3 12hr old    1563 larva L3 puffstage 1-2    1305 larva L3 puffstage 3-6    1252 larva L3 puffstage 7-9    1295 white prepupae new    1309 white prepupae 12hr    1344 white prepupae 24hr    1296 pupae 2d postWPP    1064 pupae 3d postWPP    879 pupae 4d postWPP    857 adult male 01day    739 adult male 05day    644 adult male 30day    689 adult female 01day    1540 adult female 05day    1548 adult female 30day    1482 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (1030) embryo 02-04hr  (1809) embryo 04-06hr  (2108) embryo 06-08hr  (2198) embryo 08-10hr  (2471) embryo 10-12hr  (2808) embryo 12-14hr  (1950) embryo 14-16hr  (2202) embryo 16-18hr  (1929) embryo 18-20hr  (1934) embryo 20-22hr  (2361) embryo 22-24hr  (2252) larva L1  (2511) larva L2  (2241) larva L3 12hr old  (1563) larva L3 puffstage 1-2  (1305) larva L3 puffstage 3-6  (1252) larva L3 puffstage 7-9  (1295) white prepupae new  (1309) white prepupae 12hr  (1344) white prepupae 24hr  (1296) pupae 2d postWPP  (1064) pupae 3d postWPP  (879) pupae 4d postWPP  (857) adult male 01day  (739) adult male 05day  (644) adult male 30day  (689) adult female 01day  (1540) adult female 05day  (1548) adult female 30day  (1482) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr  (1030) embryo 02-04hr  (1809) embryo 04-06hr  (2108) embryo 06-08hr  (2198) embryo 08-10hr  (2471) embryo 10-12hr  (2808) embryo 12-14hr  (1950) embryo 14-16hr  (2202) embryo 16-18hr  (1929) embryo 18-20hr  (1934) embryo 20-22hr  (2361) embryo 22-24hr  (2252) larva L1  (2511) larva L2  (2241) larva L3 12hr old  (1563) larva L3 puffstage 1-2  (1305) larva L3 puffstage 3-6  (1252) larva L3 puffstage 7-9  (1295) white prepupae new  (1309) white prepupae 12hr  (1344) white prepupae 24hr  (1296) pupae 2d postWPP  (1064) pupae 3d postWPP  (879) pupae 4d postWPP  (857) adult male 01day  (739) adult male 05day  (644) adult male 30day  (689) adult female 01day  (1540) adult female 05day  (1548) adult female 30day  (1482) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    1030 embryo 02-04hr    1809 embryo 04-06hr    2108 embryo 06-08hr    2198 embryo 08-10hr    2471 embryo 10-12hr    2808 embryo 12-14hr    1950 embryo 14-16hr    2202 embryo 16-18hr    1929 embryo 18-20hr    1934 embryo 20-22hr    2361 embryo 22-24hr    2252 larva L1    2511 larva L2    2241 larva L3 12hr old    1563 larva L3 puffstage 1-2    1305 larva L3 puffstage 3-6    1252 larva L3 puffstage 7-9    1295 white prepupae new    1309 white prepupae 12hr    1344 white prepupae 24hr    1296 pupae 2d postWPP    1064 pupae 3d postWPP    879 pupae 4d postWPP    857 adult male 01day    739 adult male 05day    644 adult male 30day    689 adult female 01day    1540 adult female 05day    1548 adult female 30day    1482 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    1030 embryo 02-04hr    1809 embryo 04-06hr    2108 embryo 06-08hr    2198 embryo 08-10hr    2471 embryo 10-12hr    2808 embryo 12-14hr    1950 embryo 14-16hr    2202 embryo 16-18hr    1929 embryo 18-20hr    1934 embryo 20-22hr    2361 embryo 22-24hr    2252 larva L1    2511 larva L2    2241 larva L3 12hr old    1563 larva L3 puffstage 1-2    1305 larva L3 puffstage 3-6    1252 larva L3 puffstage 7-9    1295 white prepupae new    1309 white prepupae 12hr    1344 white prepupae 24hr    1296 pupae 2d postWPP    1064 pupae 3d postWPP    879 pupae 4d postWPP    857 adult male 01day    739 adult male 05day    644 adult male 30day    689 adult female 01day    1540 adult female 05day    1548 adult female 30day    1482 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (1030) embryo 02-04hr  (1809) embryo 04-06hr  (2108) embryo 06-08hr  (2198) embryo 08-10hr  (2471) embryo 10-12hr  (2808) embryo 12-14hr  (1950) embryo 14-16hr  (2202) embryo 16-18hr  (1929) embryo 18-20hr  (1934) embryo 20-22hr  (2361) embryo 22-24hr  (2252) larva L1  (2511) larva L2  (2241) larva L3 12hr old  (1563) larva L3 puffstage 1-2  (1305) larva L3 puffstage 3-6  (1252) larva L3 puffstage 7-9  (1295) white prepupae new  (1309) white prepupae 12hr  (1344) white prepupae 24hr  (1296) pupae 2d postWPP  (1064) pupae 3d postWPP  (879) pupae 4d postWPP  (857) adult male 01day  (739) adult male 05day  (644) adult male 30day  (689) adult female 01day  (1540) adult female 05day  (1548) adult female 30day  (1482) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr  (1030) embryo 02-04hr  (1809) embryo 04-06hr  (2108) embryo 06-08hr  (2198) embryo 08-10hr  (2471) embryo 10-12hr  (2808) embryo 12-14hr  (1950) embryo 14-16hr  (2202) embryo 16-18hr  (1929) embryo 18-20hr  (1934) embryo 20-22hr  (2361) embryo 22-24hr  (2252) larva L1  (2511) larva L2  (2241) larva L3 12hr old  (1563) larva L3 puffstage 1-2  (1305) larva L3 puffstage 3-6  (1252) larva L3 puffstage 7-9  (1295) white prepupae new  (1309) white prepupae 12hr  (1344) white prepupae 24hr  (1296) pupae 2d postWPP  (1064) pupae 3d postWPP  (879) pupae 4d postWPP  (857) adult male 01day  (739) adult male 05day  (644) adult male 30day  (689) adult female 01day  (1540) adult female 05day  (1548) adult female 30day  (1482) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    1030 embryo 02-04hr    1809 embryo 04-06hr    2108 embryo 06-08hr    2198 embryo 08-10hr    2471 embryo 10-12hr    2808 embryo 12-14hr    1950 embryo 14-16hr    2202 embryo 16-18hr    1929 embryo 18-20hr    1934 embryo 20-22hr    2361 embryo 22-24hr    2252 larva L1    2511 larva L2    2241 larva L3 12hr old    1563 larva L3 puffstage 1-2    1305 larva L3 puffstage 3-6    1252 larva L3 puffstage 7-9    1295 white prepupae new    1309 white prepupae 12hr    1344 white prepupae 24hr    1296 pupae 2d postWPP    1064 pupae 3d postWPP    879 pupae 4d postWPP    857 adult male 01day    739 adult male 05day    644 adult male 30day    689 adult female 01day    1540 adult female 05day    1548 adult female 30day    1482 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    2168 Schneider line 2 Sg4    1230 embryonic 1182-4H    1819 embryonic GM2    1038 embryonic Kc167    1135 embryonic S1    1486 embryonic S3    857 leg disc CME L1    1888 wing disc CME-W2    802 wing disc ML-DmD8    1903 wing disc ML-DmD9    2012 wing disc ML-DmD16-c3    826 wing disc ML-DmD21    3833 wing disc ML-DmD32    1068 haltere disc ML-DmD17-c3    1103 eye-antennal disc ML-DmD11    1808 antennal disc ML-DmD20-c5    1922 mixed discs ML-DmD4-c1    2079 CNS ML-DmBG1-c1    998 CNS ML-DmBG2-c2    1744 tumorous blood cells mbn2    667 ovary fGS/OSS    1414 ovary OSC    885 ovary OSS    467 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (2168) Schneider line 2 Sg4  (1230) embryonic 1182-4H  (1819) embryonic GM2  (1038) embryonic Kc167  (1135) embryonic S1  (1486) embryonic S3  (857) leg disc CME L1  (1888) wing disc CME-W2  (802) wing disc ML-DmD8  (1903) wing disc ML-DmD9  (2012) wing disc ML-DmD16-c3  (826) wing disc ML-DmD21  (3833) wing disc ML-DmD32  (1068) haltere disc ML-DmD17-c3  (1103) eye-antennal disc ML-DmD11  (1808) antennal disc ML-DmD20-c5  (1922) mixed discs ML-DmD4-c1  (2079) CNS ML-DmBG1-c1  (998) CNS ML-DmBG2-c2  (1744) tumorous blood cells mbn2  (667) ovary fGS/OSS  (1414) ovary OSC  (885) ovary OSS  (467) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+  (2168) Schneider line 2 Sg4  (1230) embryonic 1182-4H  (1819) embryonic GM2  (1038) embryonic Kc167  (1135) embryonic S1  (1486) embryonic S3  (857) leg disc CME L1  (1888) wing disc CME-W2  (802) wing disc ML-DmD8  (1903) wing disc ML-DmD9  (2012) wing disc ML-DmD16-c3  (826) wing disc ML-DmD21  (3833) wing disc ML-DmD32  (1068) haltere disc ML-DmD17-c3  (1103) eye-antennal disc ML-DmD11  (1808) antennal disc ML-DmD20-c5  (1922) mixed discs ML-DmD4-c1  (2079) CNS ML-DmBG1-c1  (998) CNS ML-DmBG2-c2  (1744) tumorous blood cells mbn2  (667) ovary fGS/OSS  (1414) ovary OSC  (885) ovary OSS  (467) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    2168 Schneider line 2 Sg4    1230 embryonic 1182-4H    1819 embryonic GM2    1038 embryonic Kc167    1135 embryonic S1    1486 embryonic S3    857 leg disc CME L1    1888 wing disc CME-W2    802 wing disc ML-DmD8    1903 wing disc ML-DmD9    2012 wing disc ML-DmD16-c3    826 wing disc ML-DmD21    3833 wing disc ML-DmD32    1068 haltere disc ML-DmD17-c3    1103 eye-antennal disc ML-DmD11    1808 antennal disc ML-DmD20-c5    1922 mixed discs ML-DmD4-c1    2079 CNS ML-DmBG1-c1    998 CNS ML-DmBG2-c2    1744 tumorous blood cells mbn2    667 ovary fGS/OSS    1414 ovary OSC    885 ovary OSS    467 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    2168 Schneider line 2 Sg4    1230 embryonic 1182-4H    1819 embryonic GM2    1038 embryonic Kc167    1135 embryonic S1    1486 embryonic S3    857 leg disc CME L1    1888 wing disc CME-W2    802 wing disc ML-DmD8    1903 wing disc ML-DmD9    2012 wing disc ML-DmD16-c3    826 wing disc ML-DmD21    3833 wing disc ML-DmD32    1068 haltere disc ML-DmD17-c3    1103 eye-antennal disc ML-DmD11    1808 antennal disc ML-DmD20-c5    1922 mixed discs ML-DmD4-c1    2079 CNS ML-DmBG1-c1    998 CNS ML-DmBG2-c2    1744 tumorous blood cells mbn2    667 ovary fGS/OSS    1414 ovary OSC    885 ovary OSS    467 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (2168) Schneider line 2 Sg4  (1230) embryonic 1182-4H  (1819) embryonic GM2  (1038) embryonic Kc167  (1135) embryonic S1  (1486) embryonic S3  (857) leg disc CME L1  (1888) wing disc CME-W2  (802) wing disc ML-DmD8  (1903) wing disc ML-DmD9  (2012) wing disc ML-DmD16-c3  (826) wing disc ML-DmD21  (3833) wing disc ML-DmD32  (1068) haltere disc ML-DmD17-c3  (1103) eye-antennal disc ML-DmD11  (1808) antennal disc ML-DmD20-c5  (1922) mixed discs ML-DmD4-c1  (2079) CNS ML-DmBG1-c1  (998) CNS ML-DmBG2-c2  (1744) tumorous blood cells mbn2  (667) ovary fGS/OSS  (1414) ovary OSC  (885) ovary OSS  (467) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+  (2168) Schneider line 2 Sg4  (1230) embryonic 1182-4H  (1819) embryonic GM2  (1038) embryonic Kc167  (1135) embryonic S1  (1486) embryonic S3  (857) leg disc CME L1  (1888) wing disc CME-W2  (802) wing disc ML-DmD8  (1903) wing disc ML-DmD9  (2012) wing disc ML-DmD16-c3  (826) wing disc ML-DmD21  (3833) wing disc ML-DmD32  (1068) haltere disc ML-DmD17-c3  (1103) eye-antennal disc ML-DmD11  (1808) antennal disc ML-DmD20-c5  (1922) mixed discs ML-DmD4-c1  (2079) CNS ML-DmBG1-c1  (998) CNS ML-DmBG2-c2  (1744) tumorous blood cells mbn2  (667) ovary fGS/OSS  (1414) ovary OSC  (885) ovary OSS  (467) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    2168 Schneider line 2 Sg4    1230 embryonic 1182-4H    1819 embryonic GM2    1038 embryonic Kc167    1135 embryonic S1    1486 embryonic S3    857 leg disc CME L1    1888 wing disc CME-W2    802 wing disc ML-DmD8    1903 wing disc ML-DmD9    2012 wing disc ML-DmD16-c3    826 wing disc ML-DmD21    3833 wing disc ML-DmD32    1068 haltere disc ML-DmD17-c3    1103 eye-antennal disc ML-DmD11    1808 antennal disc ML-DmD20-c5    1922 mixed discs ML-DmD4-c1    2079 CNS ML-DmBG1-c1    998 CNS ML-DmBG2-c2    1744 tumorous blood cells mbn2    667 ovary fGS/OSS    1414 ovary OSC    885 ovary OSS    467 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    538 cold shock, 4-day adult    389 heat shock, 4-day adult    863 Cadmium 50 mM 6 hrs, larvae L3    847 Cadmium 50 mM 12 hrs, larvae L3    908 Cadmium 50 mM 48 hrs, 4-day adult    634 Cadmium 100 mM 48 hrs, 4-day adult    489 Copper 0.5 mM 12 hrs, larvae L3    537 Copper 15 mM 48 hrs, 4-day adult    202 Zinc 5 mM 12 hrs, larvae L3    333 Zinc 4.5 mM 48 hrs, 4-day adult    354 Ethanol 2.5% 3 hrs, larvae L3    812 Ethanol 5% 3 hrs, larvae L3    895 Ethanol 10% 3 hrs, larvae L3    975 Caffeine 1.5 mg/ml 4 hrs, larvae L3    813 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    500 Caffeine 25 mg/ml 48 hrs, 4-day adult    306 Paraquat 5 mM 48 hrs, 4-day adult    605 Paraquat 10 mM 48 hrs, 4-day adult    937 Rotenone 2 μg 12 hrs, larvae L3    868 Rotenone 8 μg 12 hrs, larvae L3    996 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult  (538) cold shock, 4-day adult  (389) heat shock, 4-day adult  (863) Cadmium 50 mM 6 hrs, larvae L3  (847) Cadmium 50 mM 12 hrs, larvae L3  (908) Cadmium 50 mM 48 hrs, 4-day adult  (634) Cadmium 100 mM 48 hrs, 4-day adult  (489) Copper 0.5 mM 12 hrs, larvae L3  (537) Copper 15 mM 48 hrs, 4-day adult  (202) Zinc 5 mM 12 hrs, larvae L3  (333) Zinc 4.5 mM 48 hrs, 4-day adult  (354) Ethanol 2.5% 3 hrs, larvae L3  (812) Ethanol 5% 3 hrs, larvae L3  (895) Ethanol 10% 3 hrs, larvae L3  (975) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (813) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (500) Caffeine 25 mg/ml 48 hrs, 4-day adult  (306) Paraquat 5 mM 48 hrs, 4-day adult  (605) Paraquat 10 mM 48 hrs, 4-day adult  (937) Rotenone 2 μg 12 hrs, larvae L3  (868) Rotenone 8 μg 12 hrs, larvae L3  (996) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult  (538) cold shock, 4-day adult  (389) heat shock, 4-day adult  (863) Cadmium 50 mM 6 hrs, larvae L3  (847) Cadmium 50 mM 12 hrs, larvae L3  (908) Cadmium 50 mM 48 hrs, 4-day adult  (634) Cadmium 100 mM 48 hrs, 4-day adult  (489) Copper 0.5 mM 12 hrs, larvae L3  (537) Copper 15 mM 48 hrs, 4-day adult  (202) Zinc 5 mM 12 hrs, larvae L3  (333) Zinc 4.5 mM 48 hrs, 4-day adult  (354) Ethanol 2.5% 3 hrs, larvae L3  (812) Ethanol 5% 3 hrs, larvae L3  (895) Ethanol 10% 3 hrs, larvae L3  (975) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (813) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (500) Caffeine 25 mg/ml 48 hrs, 4-day adult  (306) Paraquat 5 mM 48 hrs, 4-day adult  (605) Paraquat 10 mM 48 hrs, 4-day adult  (937) Rotenone 2 μg 12 hrs, larvae L3  (868) Rotenone 8 μg 12 hrs, larvae L3  (996) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    538 cold shock, 4-day adult    389 heat shock, 4-day adult    863 Cadmium 50 mM 6 hrs, larvae L3    847 Cadmium 50 mM 12 hrs, larvae L3    908 Cadmium 50 mM 48 hrs, 4-day adult    634 Cadmium 100 mM 48 hrs, 4-day adult    489 Copper 0.5 mM 12 hrs, larvae L3    537 Copper 15 mM 48 hrs, 4-day adult    202 Zinc 5 mM 12 hrs, larvae L3    333 Zinc 4.5 mM 48 hrs, 4-day adult    354 Ethanol 2.5% 3 hrs, larvae L3    812 Ethanol 5% 3 hrs, larvae L3    895 Ethanol 10% 3 hrs, larvae L3    975 Caffeine 1.5 mg/ml 4 hrs, larvae L3    813 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    500 Caffeine 25 mg/ml 48 hrs, 4-day adult    306 Paraquat 5 mM 48 hrs, 4-day adult    605 Paraquat 10 mM 48 hrs, 4-day adult    937 Rotenone 2 μg 12 hrs, larvae L3    868 Rotenone 8 μg 12 hrs, larvae L3    996 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    538 cold shock, 4-day adult    389 heat shock, 4-day adult    863 Cadmium 50 mM 6 hrs, larvae L3    847 Cadmium 50 mM 12 hrs, larvae L3    908 Cadmium 50 mM 48 hrs, 4-day adult    634 Cadmium 100 mM 48 hrs, 4-day adult    489 Copper 0.5 mM 12 hrs, larvae L3    537 Copper 15 mM 48 hrs, 4-day adult    202 Zinc 5 mM 12 hrs, larvae L3    333 Zinc 4.5 mM 48 hrs, 4-day adult    354 Ethanol 2.5% 3 hrs, larvae L3    812 Ethanol 5% 3 hrs, larvae L3    895 Ethanol 10% 3 hrs, larvae L3    975 Caffeine 1.5 mg/ml 4 hrs, larvae L3    813 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    500 Caffeine 25 mg/ml 48 hrs, 4-day adult    306 Paraquat 5 mM 48 hrs, 4-day adult    605 Paraquat 10 mM 48 hrs, 4-day adult    937 Rotenone 2 μg 12 hrs, larvae L3    868 Rotenone 8 μg 12 hrs, larvae L3    996 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult  (538) cold shock, 4-day adult  (389) heat shock, 4-day adult  (863) Cadmium 50 mM 6 hrs, larvae L3  (847) Cadmium 50 mM 12 hrs, larvae L3  (908) Cadmium 50 mM 48 hrs, 4-day adult  (634) Cadmium 100 mM 48 hrs, 4-day adult  (489) Copper 0.5 mM 12 hrs, larvae L3  (537) Copper 15 mM 48 hrs, 4-day adult  (202) Zinc 5 mM 12 hrs, larvae L3  (333) Zinc 4.5 mM 48 hrs, 4-day adult  (354) Ethanol 2.5% 3 hrs, larvae L3  (812) Ethanol 5% 3 hrs, larvae L3  (895) Ethanol 10% 3 hrs, larvae L3  (975) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (813) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (500) Caffeine 25 mg/ml 48 hrs, 4-day adult  (306) Paraquat 5 mM 48 hrs, 4-day adult  (605) Paraquat 10 mM 48 hrs, 4-day adult  (937) Rotenone 2 μg 12 hrs, larvae L3  (868) Rotenone 8 μg 12 hrs, larvae L3  (996) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult  (538) cold shock, 4-day adult  (389) heat shock, 4-day adult  (863) Cadmium 50 mM 6 hrs, larvae L3  (847) Cadmium 50 mM 12 hrs, larvae L3  (908) Cadmium 50 mM 48 hrs, 4-day adult  (634) Cadmium 100 mM 48 hrs, 4-day adult  (489) Copper 0.5 mM 12 hrs, larvae L3  (537) Copper 15 mM 48 hrs, 4-day adult  (202) Zinc 5 mM 12 hrs, larvae L3  (333) Zinc 4.5 mM 48 hrs, 4-day adult  (354) Ethanol 2.5% 3 hrs, larvae L3  (812) Ethanol 5% 3 hrs, larvae L3  (895) Ethanol 10% 3 hrs, larvae L3  (975) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (813) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (500) Caffeine 25 mg/ml 48 hrs, 4-day adult  (306) Paraquat 5 mM 48 hrs, 4-day adult  (605) Paraquat 10 mM 48 hrs, 4-day adult  (937) Rotenone 2 μg 12 hrs, larvae L3  (868) Rotenone 8 μg 12 hrs, larvae L3  (996) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    538 cold shock, 4-day adult    389 heat shock, 4-day adult    863 Cadmium 50 mM 6 hrs, larvae L3    847 Cadmium 50 mM 12 hrs, larvae L3    908 Cadmium 50 mM 48 hrs, 4-day adult    634 Cadmium 100 mM 48 hrs, 4-day adult    489 Copper 0.5 mM 12 hrs, larvae L3    537 Copper 15 mM 48 hrs, 4-day adult    202 Zinc 5 mM 12 hrs, larvae L3    333 Zinc 4.5 mM 48 hrs, 4-day adult    354 Ethanol 2.5% 3 hrs, larvae L3    812 Ethanol 5% 3 hrs, larvae L3    895 Ethanol 10% 3 hrs, larvae L3    975 Caffeine 1.5 mg/ml 4 hrs, larvae L3    813 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    500 Caffeine 25 mg/ml 48 hrs, 4-day adult    306 Paraquat 5 mM 48 hrs, 4-day adult    605 Paraquat 10 mM 48 hrs, 4-day adult    937 Rotenone 2 μg 12 hrs, larvae L3    868 Rotenone 8 μg 12 hrs, larvae L3    996 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_22 mE1_20_mRNA_expression_cluster_01
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0036213 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG7283-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal RpL10AbCB02653 lethal, with Scer\GAL4pnr-MD237 RpL10AbGD13519 lethal | pupal stage, with Scer\GAL4pnr-MD237 RpL10AbGD13519 Phenotype manifest in Allele
Classical Alleles ( 4 )
For All Classical Alleles Show
Allele of RpL10Ab Class Mutagen Stocks Known lesion RpL10AbKG09231 P-element activity 2 -- RpL10Abc03865 piggyBac transposase 1 -- RpL10AbCB02653 P-element activity 0 Yes RpL10AbCPTI003957 piggyBac transposase 0 Yes
Alleles Carried on Transgenic Constructs ( 6 )
For All Alleles Carried on Transgenic Constructs Show
Allele of RpL10Ab Class Mutagen Stocks Known lesion RpL10AbScer\UAS.T:Avic\GFP-EGFP in vitro construct - regulatory fusion in vitro construct - coding region fusion 3 Yes RpL10AbGD13519 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes RpL10AbGD16837 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes RpL10AbHMS01174 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes RpL10AbKK114901 in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes RpL10AbNIG.7283R in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(3L)CycA3 (Lehner, 2013.1.1) Df(3L)ED4475 (Marygold et al., 2007) Df(3L)Exel6115 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD13519} NA P{GD16837} NA P{KK114901} NA P{NIG.7283R} NA P{TRiP.HMS01174} NA P{UAS-GFP-RpL10Ab} NA
Insertions
	Type of insertions Name Expression data miscellaneous insertions P{PTT-GB}RpL10AbCB02653 NA P{SUPor-P}KG00223 NA P{SUPor-P}RpL10AbKG09231 NA PBac{802.P.SVS-2}RpL10AbCPTI003957 NA PBac{PB}RpL10Abc03865 NA
Gene Ontology: Function, Process & Cellular Component ( 7 unique terms )
Terms Based on Experimental Evidence ( 3 terms )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
centrosome duplication inferred from mutant phenotype (Müller et al., 2010) mitotic spindle elongation inferred from mutant phenotype (Goshima et al., 2007) mitotic spindle organization inferred from mutant phenotype (Goshima et al., 2007)
Cellular Component ( 0 terms)
Terms Based on Predictions or Assertions ( 4 terms )
Molecular Function
CV term Evidence References
RNA binding inferred from electronic annotation with InterPro:IPR002143, InterPro:IPR023674 (FlyBase Curators et al., 2004-) structural constituent of ribosome inferred from sequence or structural similarity with UniProtKB:P52859 (FlyBase, 1992-)
Biological Process
CV term Evidence References
translation inferred from sequence or structural similarity with UniProtKB:P52859 (FlyBase, 1992-)
Cellular Component
CV term Evidence References
cytosolic large ribosomal subunit inferred from sequence or structural similarity with UniProtKB:P52859 (FlyBase, 1992-)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions RpL10Ab allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 64699 DroID - A comprehensive database of gene and protein interactions. • FBgn0036213 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 39338
Orthologs
OrthoDB Orthologs (45) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6907WD Dipteran inclusive ortholog search EOG64J2T6 Insect inclusive ortholog search EOG6RBPFW Arthropod inclusive ortholog search EOG6MGQQK Metazoa inclusive ortholog search EOG6HXHVR
Orthologs in Drosophila Species (EOG6907WD)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\RpL10Ab     Drosophila simulans   Dsim\GD14333 Y   Drosophila sechellia   Dsec\GM25301 Y   Drosophila erecta   Dere\GG15534 Y   Drosophila yakuba   Dyak\GE21853 Y   Drosophila ananassae   Dana\GF24510 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA20236 Y   Drosophila persimilis   Dper\GL20818     Drosophila willistoni   Dwil\GK13682 Y   Drosophila virilis   Dvir\GJ11814 Y   Drosophila grimshawi   Dgri\GH16724 Y
Orthologs in non-Drosophila Dipterans (EOG64J2T6)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL013221   Anopheles gambiae Malaria mosquito  Agam\AGAP011298   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ001270
Orthologs in non-Dipteran Insects (EOG6RBPFW)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\GB40777   Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG010806   Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH15355   Atta cephalotes Leafcutter ant  Acep\ACEP12894   Camponotus floridanus Florida carpenter ant  Cflo\CFLO15795   Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL17581   Linepithema humile Argentine ant  Lhum\LH22931   Pogonomyrmex barbatus Red harvester ant  Pbar\PB25666   Solenopsis invicta Red fire ant  Sinv\SINV17450   Acyrthosiphon pisum Pea aphid  Apim\ACYPI004435   Bombyx mori Silkmoth  Bmor\BGIBMGA003337   Pediculus humanus Human body louse  Phum\PHUM261640   Tribolium castaneum Red flour beetle  Tcas\GLEAN_07324
Orthologs in non-Insect Arthropods (EOG6MGQQK)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\alpha-LP   Ixodes scapularis Deer tick  Isca\ISCW015602
Orthologs in non-Arthropod Metazoa (EOG6HXHVR)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Caenorhabditis elegans Nematode  Cele\rpl-10a Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_022726gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_016005gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_017686gn Y Danio rerio Zebrafish  Drer\rpl10a Y Xenopus tropicalis Western clawed frog  Xtro\rpl10a Y Gallus gallus Domestic chicken  Ggal\RPL10A Y Mus musculus House mouse  Mmus\Rpl10a-ps2 Y Mus musculus House mouse  Mmus\Rpl10a Y Rattus norvegicus Norway rat  Rnor\Rpl10a Y Rattus norvegicus Norway rat  Rnor\LOC680700 Y Rattus norvegicus Norway rat  Rnor\RGD1566137 Y Rattus norvegicus Norway rat  Rnor\ENSRNOG00000031764 Y Rattus norvegicus Norway rat  Rnor\RGD1559639 Y Rattus norvegicus Norway rat  Rnor\RGD1562962 Y Homo sapiens Human  Hsap\RPL10A Y
Human Orthologs (1)
Gene OMIM HGNC Hsap\RPL10A
AAA Orthologs (10) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD14333 Drosophila sechellia Dsec\GM25301 Drosophila erecta Dere\GG15534 Drosophila yakuba Dyak\GE21853 Drosophila ananassae Dana\GF24510 Drosophila pseudoobscura pseudoobscura Dpse\GA20236 Drosophila willistoni Dwil\GK13682 Drosophila virilis Dvir\GJ11814 Drosophila mojavensis Dmoj\GI13453 Drosophila grimshawi Dgri\GH16724
Stocks & Reagents
Stocks Listed in FlyBase ( 10 )
Bloomington	42681 w*; P{UAS-GFP-RpL10Ab}BF2b 42683 w*; P{UAS-GFP-RpL10Ab}BF27 42682 P{UAS-GFP-RpL10Ab}BF24, w*; l(2)**/CyO 34695 y1 sc* v1; P{TRiP.HMS01174}attP2/TM3, Sb1 15173 y1; P{SUPor-P}RpL10AbKG09231 ry506/TM3, Sb1 Ser1
Harvard	- PBac{PB}RpL10Abc03865
Kyoto	111689 yd2 w1118 P{ey-FLP.N}2 P{GMR-lacZ.C(38.1)}TPN1; P{SUPor-P}RpL10AbKG09231 P{neoFRT}80B/TM6B, P{Car20y}TPN1, Tb1
VDRC	v52411 w1118 P{GD16837}v52411 v23458 w1118; P{GD13519}v23458 v23459 w1118; P{GD13519}v23459
Genomic Clones ( 1 )
	BACR48G03 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 520 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	RE06042 RH06366 RH43519
Other clones	yak-ad_CG7283 yak-em_CG7283
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT10212 AT26116 AT30718 GH05501 GH05513 GH06033 GH08284 GH08481 GH13160 GH14003 GH15239 GH19351 GH20152 GH22393 GH25684 GH26051 GM01719 GM02857 GM03333 GM03944 GM05409 GM08002 GM08456 GM09457 GM12835 GM13279 GM14123 GM14370 GM14754 GM16673 GM18194 GM19314 GM20020 GM22488 GM22620 GM22644 GM22973 GM24032 GM26907 GM28380 GM31121 GM31660 LD02202 LD06080 LD13233 LD14802 LD21218 LD35560 LD38255 LD38343 LD44509 LD47337 LP08214 LP14666 LP14772 LP15142 LP15143 LP15705 LP18409 LP23731 RE18883 RE19016 RE21862 RE22493 RE24761 RE25120 RE26512 RE27309 RE27867 RE28443 RE28980 RE29632 RE30777 RE31080 RE32427 RE32438 RE35252 RE37081 RE39511 RE39635 RE40014 RE40422 RE42263 RE43630 RE43709 RE44095 RE44529 RE46366 RE46711 RE48658 RE51458 RE52208 RE55045 RE55759 RE58389 RE58635 RE60750 RE61012 RE61674 RE64144 RE64836 RE65076 RE66142 RE66676 RE67644 RE69477 RE70205 RE70284 RE70546 RE71913 RE73234 RE73413 RE73793 RE74113 RE74647 RE74846 RH29487 RH33614 RH39301 RH42394 RH43102 RH43159 RH43392 RH43874 RH54441 RH58444 RH61870 RH68155 RH70676 SD01261 SD05616 SD07002 SD12032 SD13566 SD13576 SD13955 SD15863 SD15976 UT01216
Other clones	11924 51961 53084 76102 79449 82623 521967 522607 523224 523698 524014 524132 524638 542482 557913 558013 569811 572932 bs11b12 CK01.42C.C3 CK01.52B.F12 CK01.88B.C12 CK01.91A.A6 Dmel_dig_000507_0688_3643 Dmel_dig_002188_0589_1549 Dmel_dig_002230_0645_2346 Dmel_dig_002593_0637_0324 Dmel_dig_003020_0637_1497 Dmel_dig_004157_0698_3711 Dmel_dig_004751_0695_2195 Dmel_dig_005965_0660_1078 Dmel_dig_006227_0648_3317 Dmel_dig_006683_0616_1515 Dmel_dig_007369_0620_3272 Dmel_dig_007655_0584_2241 Dmel_dig_008267_0658_2694 Dmel_dig_008953_0644_1798 Dmel_dig_009450_0685_1533 Dmel_dig_010568_0684_3530 Dmel_dig_010842_0692_2823 Dmel_dig_011902_0587_1144 Dmel_dig_013117_0660_2501 Dmel_dig_013317_0704_1627 Dmel_dig_013927_0705_1303 Dmel_dig_014040_0644_0924 Dmel_dig_014177_0713_1294 Dmel_dig_014270_0598_0778 Dmel_dig_016832_0594_3550 Dmel_dig_020722_0591_1492 Dmel_neb_009854_0940_3208 Dmel_neb_010389_0655_1179 Dmel_neb_010830_0608_0540 Dmel_neb_011246_0948_2915 Dmel_neb_011683_0949_1014 Dmel_neb_012196_0186_0504 Dmel_neb_013295_0633_1269 Dmel_neb_013803_0160_2071 Dmel_neb_013832_0432_1063 Dmel_neb_014510_0691_1368 Dmel_neb_014738_0586_0485 Dmel_neb_014884_0694_3427 Dmel_neb_015170_0955_0992 Dmel_neb_015878_0335_1741 Dmel_neb_015905_0691_1769 Dmel_neb_015912_0940_1202 Dmel_neb_015927_0866_2796 Dmel_neb_015932_0697_3435 EC00587 EC01394 EC01587 EC13234 EC14813 EC25607 EC26146 EC26207 EC28027 EC28646 EC30578 EC37220 EC39214 EC39709 EC40509 EC40694 EC40720 EK042454 EK069642 EK071335 EK112048 EK169559 EK209761 EK216350 EK260607 EN01111 EN02438 EN03649 EN04614 EN04829 EN05613 EN10716 EN15651 EN17535 ESG014a.E21_C01 ESG018b.E21_G02 FGA002C05 FGA006B12 FGA007F10 FGB001C08 FGC003C08 FGC005A11 FGC014C12 FGC015A01 FGC015G06 FGC017E04 FGC017F02 FGC019H10 FGC020A05 FGC021B05 FGC021E02 FGC023A02 FGC023C08 FGC023H06 FGC025C03 FGC026F04 FGC027A06 FGC028C10 FGC029A05 FGC029E10 FGC029H03 FGC030B11 FGH001C12 FGH101A06 FGH101B09 FGH101G04 FGH102C07 FGH103B07 FGH103C01 FGH103E04 FGH104D04 FGH105A08 FGH105C09 FGH105G05 FGH105G09 FGH107C05 FGH107C07 FGH110C11 FGH110E07 FGH110F05 FGH110F12 FGH111F06 FGH112D05 FGH112E03 FGH112G08 FGH114G03 FGH116C11 FGH116F01 FGH116G05 FGH118B02 FGH119C07 FGH119F10 FGH119F11 FGH120D11 FGH125E03 FGH125H09 FGH129A07 FGH129A09 FGH129C11 FGH129G02 FGM102D08 FGM104D10 FGM105H05 FGM206F12 FGM206H10 FGM220A06 FGM222F08 FGM227D06 FGM229D01 FGM232G06 FGM233B03 FGM233C06 FGM237C10 FGM302B12 FGM304F02 FGM305A12 FGM307E01 FGM307G08 FGM311B09 FGM311D11 FGM312E06 FGM313A10 FGM317D08 FGM319E02 FGM322E11 FGM323A08 FGM324E05 FGM324H12 FGM325C09 FGM325F01 GH01291 GH05141 GH07021 GH11948 GH14478 GM08780 IP01810 IP05528 LD17035 LD21480 LD23730 LD27369 LD39681 LP07152 LP07318 LP15107 LP15942 LP22870 RE01318 RE01418 RE01488 RE02031 RE02063 RE04458 RE04680 RE05578 RE06793 RE08425 RE09096 RE09781 RE10114 RE11025 RE11366 RE12354 RE12713 RE12831 RE13482 RE14562 RE14823 RE16330 RE17026 RE18702 RE20954 RE25563 RE32719 RE32775 RE34203 RE34548 RE35901 RE38605 RE40547 RE42049 RE47023 RE47465 RE49848 RE58142 RE61212 RE62610 RE62646 RE63678 RE63936 RE63952 RH07409 RH13577 RH60120 RH69286 RP003006175 RP003007767 RP003015223 RP003039739 RP003052127 RP003053070 RP003054584 RP003068383 RP003073588 RP003073979 RP003077487 RP003077837 RP003080738 RP003084663 RP003086892 RP003087621 RP003087806 RP003089116 RP003095809 RP003105803 RP003113787 RP003115483 RP003122545 RP003123689 RP003123727 RP003128549 RP003130011 RP003130987 RP003139902 RP003156488 RP003158396 RP003180638 RP003184329 RP003189604 RP003194094 RP003195518 RP003204442 RP003212696 RP003220264 RP003227060 RP003227968 RP003229257 RP003232844 RP003245963 RP003256839 RP003269645 RP003274837 RP003276174 RP003293486 RP003301150 RP003302876 RP003308438 RP003309680 RP003316102 RP003317670 RP003322095 RP003324002 RP003324426 RP003324598 RP003324871 RP003325311 RP003326440 RP003328834 RP003329418 RP003351798 RP003352784 RP003356319 RP003357445 RP003385724 RP003405137 RP003429860 RP003433938 RP003435430 RP003436822 RP003437452 RP003444119 RP003451643 RP003458321 RP003460848 RP003476603 RP003489055 RP003491026 RP003492254 RP003499174 RP003499534 RP003500145 RP003504169 RP003507399 RP003516641 RP003539148 RP003546256 RP003558014 RP003560593 RP003562405 RP003568810 RP003569873 RP003576818 RP003583663 RP003590408 RP003606070 RP003609702 RP003625917 RP003626887 RP003635087 RP003640637 RP003642376 RP003645452 RP003650129 RP003665080 UT01284 UT01838 UUGC0073 UUGC0236
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0036213 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 39338
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of	Source for merge of: CG7283 anon-EST:Posey188 (Bayraktaroglu, 2000.11.2) Source for merge of: CG7283 BcDNA:RH06366 (FlyBase, 1996-)
Additional comments	Source for merge of CG7283 BcDNA:RH06366 was a shared cDNA (date:030728). (FlyBase, 1996-)
Other Comments
	Nonsense-mediated mRNA decay (NMD) down-regulates a distinct splice isoform(s) of this gene. (Hansen et al., 2009) RNAi screen using dsRNA made from templates generated with primers directed against this gene results in aberrantly short, monopolar spindles when assayed in S2 cells. This phenotype can be observed when the screen is performed with or without Cdc27 dsRNA. (Goshima et al., 2007) Not a Minute gene. (Marygold et al., 2007) Deletions removing RpL10Ab but no other cytoplasmic ribosomal protein-encoding genes do not show Minute phenotypes. (Marygold et al., 2007) RNAi generated by PCR using primers directed to this gene causes a cell growth and viability phenotype when assayed in Kc167 and S2R+ cells. (Boutros et al., 2004)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_140257 NM_168481 NM_001259794 RefSeq (Proteins) • NP_648514 NP_729754 NP_001246723 DDBJ / EMBL / GenBank • AAF50002 AAN12245 AAN71513 AAN71580 AF083291 AFH04394 AI388435 AI945300 BI166023 BI362206 BI591616 BI614198 BT001758 BT001825 BZ665670 CZ468858 CZ468859 Entrez Gene - A searchable database of RefSeq genes. • 39338 UniProtKB/Swiss-Prot • Q9VTP4 UniProtKB/TrEMBL • Q8IGE1 Q8IGJ3
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Ribosomal protein L1 (IPR002143) Ribosomal protein L1, 3-layer alpha/beta-sandwich (IPR016095) Ribosomal protein L1, 2-layer alpha/beta-sandwich (IPR016094) Ribosomal protein L1, superfamily (IPR023674)
Linkouts
	BioGRID - A database of protein and genetic interactions • 64699 DroID - A comprehensive database of gene and protein interactions. • FBgn0036213 DRSC - Results from RNAi screens. • FBgn0036213 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0036213 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG7283-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0036213 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 39338 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 39338 modMine - Data generated by the modENCODE project. • FBgn0036213
Synonyms & Secondary IDs ( 8 )
Reported As
Symbol Synonym	anon-EST:Posey188   BcDNA:RH06366   CG7283 (Boutros et al., 2004, Huang et al., 2005, Goshima et al., 2007, Hansen et al., 2009, Marygold et al., 2007, Ni et al., 2010.12.1, Keleman et al., 2009.8.5, Cammarato et al., 2011, Lehner, 2013.1.1, Yano et al., 2012) L10Ab (Carpenter et al., 2009) RpL10A (Thomas et al., 2012) RpL10Ab (Beller et al., 2006, Fischer et al., 2012, Buszczak et al., 2007, Wonglapsuwan et al., 2011, Nie et al., 2009, Hansen et al., 2009, Marygold et al., 2007, Neumüller et al., 2011, Lehner, 2013.1.1, Japanese National Institute of Genetics, 2012.5.21, Thomas et al., 2012) RpL10Ae (Goshima et al., 2007)
Name Synonym	Ribosomal protein L10Ab (Ashburner and Marygold, 2004.7.2, Cammarato et al., 2011, Yano et al., 2012)
Secondary FlyBase IDs
	FBgn0026276 FBgn0064847
References ( 42 )
Generate a list of	All references relating to this gene ( 42 )
List References by type	Research paper  ( 16 ) Supplementary material  ( 8 ) Personal communication to FlyBase  ( 13 ) FlyBase analysis  ( 2 ) Stock list  ( 1 ) Curated genome annotation  ( 2 )
Recent research papers ( 7 )
	Fischer et al., 2012, Proc. Biol. Sci. 279(1738): 2636--2644 Conserved properties of Drosophila and human spermatozoal mRNA repertoires. [FBrf0218415] Thomas et al., 2012, PLoS ONE 7(7): e40276 A Versatile Method for Cell-Specific Profiling of Translated mRNAs in Drosophila. [FBrf0218903] Yano et al., 2012, J. Neurogenet. 26(1): 53--63 Identification of proteasome components required for apical localization of chaoptin using functional genomics. [FBrf0217843] Booker et al., 2011, BMC Genomics 12: 50 False negative rates in Drosophila cell-based RNAi screens: a case study. [FBrf0212969] Casad et al., 2011, Genetics 189(3): 861--870 Cardiomyopathy Is Associated with Ribosomal Protein Gene Haplo-Insufficiency in Drosophila melanogaster. [FBrf0216591] Neumüller et al., 2011, Cell Stem Cell 8(5): 580--593 Genome-Wide Analysis of Self-Renewal in Drosophila Neural Stem Cells by Transgenic RNAi. [FBrf0213621] Wonglapsuwan et al., 2011, Gen. Comp. Endocrinol. 173(2): 356--363 RpL10A regulates oogenesis progression in the banana prawn Fenneropenaeus merguiensis and Drosophila melanogaster. [FBrf0214620] Show all research papers ...