Gene model reviewed during 5.43
Low-frequency RNA-Seq exon junction(s) not annotated.
Annotated transcripts do not represent all possible combinations of alternative exons and/or alternative promoters.
Gene model reviewed during 5.46
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\RhoGAP68F using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\RhoGAP68F in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
RhoGAP68F localises preferentially to Rab4 endosomes and forms a complex with the Rab4 protein. RhoGAP68F inhibits the direct return of Rab4 endosomes containing Fas3 and shg back to the cell surface. The upregulation of RhoGAP68F during prepupal development is thus predicted to result in decreased transport of key cell adhesion proteins to the cell surface, decreasing the strength of cell-cell contacts and facilitating epithelial remodeling during morphogenesis.
dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology.