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Gene Dmel\CG5642

General Information
Symbol	Dmel\CG5642	Species	D. melanogaster
Name		Annotation symbol	CG5642
Feature type	protein_coding_gene	FlyBase ID	FBgn0036258
Gene Model Status	Current	Stock availability	3 publicly available
Genomic Location
Chromosome (arm)	3L	Recombination map
Cytogenetic map	68F6-68F6	Sequence location	3L:12,136,546..12,139,197 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG5642 (FBgn0036258). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: translation initiation factor activity. There is experimental evidence that it is involved in the biological process: neuron projection morphogenesis. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Translation initiation factor 3 complex, subunit L. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of high expression. Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes. Summary of FlyAtlas Anatomical Expression Data: High levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male reproductive system, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1631527_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG5642. Gene sequence location is 3L:12136546..12139197.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 68F6-68F6   Limits computationally determined from genome sequence between P{PZ}rols08232&P{lacW}l(3)j2D3j2D3 and P{PZ}l(3)0508805088
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG5642 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.43 Gene model reviewed during 5.46 Low-frequency RNA-Seq exon junction(s) not annotated.
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG5642-RA FBtr0076022  NM_140296   1834   539
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG5642-PA   FBpp0075754   63.2   539   5.83     NP_648553   AAF49952
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Translation initiation factor 3 complex subunit L (IPR019382)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA201983   AA202683   AA263548   AA263654   AA264421   AA264577   AA390344   AA390645   AA391709   AA392815   AA439198   AA439223   AA440974   AA536413   AA539829   AA694672   AA695510   AA695650   AA696986   AA698488   AA698489   AA735362   AA735852   AA736138   AA803556   AA817530   AA940720   AA951865   AA978675   AE014296 AAF49952   AI063861   AI107135   AI135902   AI238290   AI238917   AI292898   AI295769   AI296726   AI456910   AI514412   AI515407   AI516333   AI517522   AI520441   AI532537   AI544209   AY089607 AAL90345   BF496743   BG635287   BG636327   BG641394   BI172684   BI215325   BI215700   BI228594   BI231091   BI232090   BI239762   BI239923   BI352284   BI352395   BI352870   BI364385   BI365972   BI371741   BI372955   BI374758   BI487138   BI625890   BI626798   BI640845   BP547664   BP548402   BQ102817   BX027681   CK605371   CK605372   CK659050   CK659215   CO292521   CO321642   CO322267   CO332422   CO337475   CO337595   CO338183   CO338876   EC081962   EC085978   EC224524   EC235599   EC239750   EC264311   EC264375   EC265364   EC266999   EV575464   EV581710   EV582304   EV585700   EV588362   EV588841   GH748733   GH752231   GH771836   GH773245   GH777009   GH783889   GH784488   GH792958   GH794565   GH795591   GH800687   GH801894   GH802570   GH808581   GH811207   GH811629   GH812106   GH819941   GH824390   GH826421   GH837103   GH853908   GH858095   GH866047   GH867954   GH872205   GH875615   GH880602   GH881657   GH886450   GH896584   GH898387   GH910612   GH913370   GH915719   GH918787   GH932503   GH934035   GH937216   GH938278
UniProtKB/Swiss-Prot	Q9VTU4
UniProtKB/TrEMBL
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
in situ Stage Tissue/Position (including subcellular localization) Reference embryonic stage 1 -- 3   organism   (Fisher et al., 2012) Comment:maternally deposited embryonic stage 4 -- 6   organism   (Fisher et al., 2012) embryonic stage 7 -- 8   organism | ubiquitous   (Fisher et al., 2012) embryonic stage 9 -- 10   organism | ubiquitous   (Fisher et al., 2012) embryonic stage 11 -- 12   organism | ubiquitous   (Fisher et al., 2012) embryonic stage 13 -- 16   organism | ubiquitous   (Fisher et al., 2012)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
mass spectroscopy Stage Tissue/Position (including subcellular localization) Reference day 7 of adulthood -- day 49 of adulthood   adult heart   (Cammarato et al., 2011)
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: High levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male reproductive system, larval/adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    1270.95 Larval Midgut    639.6 Larval Hindgut    1276.8 Larval Malpighian Tubules    1322.5 Larval Fat Body    1313 Larval Salivary Gland    1750.3 Larval Trachea    1403.05 Larval Carcass    1087.675 Adult Head    1231.5 Adult Eye    2133.65 Adult Brain    1068.8 Adult Thoracic-Abdominal Ganglion    1822.9 Adult Crop    1205.1 Adult Midgut    724.2 Adult Hindgut    1028.7 Adult Malpighian Tubules    847.1 Adult Fat Body    1595.3 Adult Salivary Gland    1241.4 Adult Heart    1099.4 Adult VirginFemale Spermatheca    1873.8 Adult InseminatedFemale Spermatheca    1836.5 Adult Ovary    1286.3 Adult Testis    504.2 Adult Male Accessory Gland    2594 Adult Carcass    1050.2 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System  (1270.95) Larval Midgut  (639.6) Larval Hindgut  (1276.8) Larval Malpighian Tubules  (1322.5) Larval Fat Body  (1313) Larval Salivary Gland  (1750.3) Larval Trachea  (1403.05) Larval Carcass  (1087.675) Adult Head  (1231.5) Adult Eye  (2133.65) Adult Brain  (1068.8) Adult Thoracic-Abdominal Ganglion  (1822.9) Adult Crop  (1205.1) Adult Midgut  (724.2) Adult Hindgut  (1028.7) Adult Malpighian Tubules  (847.1) Adult Fat Body  (1595.3) Adult Salivary Gland  (1241.4) Adult Heart  (1099.4) Adult VirginFemale Spermatheca  (1873.8) Adult InseminatedFemale Spermatheca  (1836.5) Adult Ovary  (1286.3) Adult Testis  504.2 Adult Male Accessory Gland  (2594) Adult Carcass  (1050.2) Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System  (1270.95) Larval Midgut    639.6 Larval Hindgut  (1276.8) Larval Malpighian Tubules  (1322.5) Larval Fat Body  (1313) Larval Salivary Gland  (1750.3) Larval Trachea  (1403.05) Larval Carcass  (1087.675) Adult Head  (1231.5) Adult Eye  (2133.65) Adult Brain  1068.8 Adult Thoracic-Abdominal Ganglion  (1822.9) Adult Crop  (1205.1) Adult Midgut    724.2 Adult Hindgut  1028.7 Adult Malpighian Tubules    847.1 Adult Fat Body  (1595.3) Adult Salivary Gland  (1241.4) Adult Heart  (1099.4) Adult VirginFemale Spermatheca  (1873.8) Adult InseminatedFemale Spermatheca  (1836.5) Adult Ovary  (1286.3) Adult Testis    504.2 Adult Male Accessory Gland  (2594) Adult Carcass  1050.2 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    1270.95 Larval Midgut    639.6 Larval Hindgut    1276.8 Larval Malpighian Tubules    1322.5 Larval Fat Body    1313 Larval Salivary Gland    1750.3 Larval Trachea    1403.05 Larval Carcass    1087.675 Adult Head    1231.5 Adult Eye    2133.65 Adult Brain    1068.8 Adult Thoracic-Abdominal Ganglion    1822.9 Adult Crop    1205.1 Adult Midgut    724.2 Adult Hindgut    1028.7 Adult Malpighian Tubules    847.1 Adult Fat Body    1595.3 Adult Salivary Gland    1241.4 Adult Heart    1099.4 Adult VirginFemale Spermatheca    1873.8 Adult InseminatedFemale Spermatheca    1836.5 Adult Ovary    1286.3 Adult Testis    504.2 Adult Male Accessory Gland    2594 Adult Carcass    1050.2 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    1270.95 Larval Midgut    639.6 Larval Hindgut    1276.8 Larval Malpighian Tubules    1322.5 Larval Fat Body    1313 Larval Salivary Gland    1750.3 Larval Trachea    1403.05 Larval Carcass    1087.675 Adult Head    1231.5 Adult Eye    2133.65 Adult Brain    1068.8 Adult Thoracic-Abdominal Ganglion    1822.9 Adult Crop    1205.1 Adult Midgut    724.2 Adult Hindgut    1028.7 Adult Malpighian Tubules    847.1 Adult Fat Body    1595.3 Adult Salivary Gland    1241.4 Adult Heart    1099.4 Adult VirginFemale Spermatheca    1873.8 Adult InseminatedFemale Spermatheca    1836.5 Adult Ovary    1286.3 Adult Testis    504.2 Adult Male Accessory Gland    2594 Adult Carcass    1050.2 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System  (1270.95) Larval Midgut  639.6 Larval Hindgut  (1276.8) Larval Malpighian Tubules  (1322.5) Larval Fat Body  (1313) Larval Salivary Gland  (1750.3) Larval Trachea  (1403.05) Larval Carcass  (1087.675) Adult Head  (1231.5) Adult Eye  (2133.65) Adult Brain  (1068.8) Adult Thoracic-Abdominal Ganglion  (1822.9) Adult Crop  (1205.1) Adult Midgut  724.2 Adult Hindgut  (1028.7) Adult Malpighian Tubules  (847.1) Adult Fat Body  (1595.3) Adult Salivary Gland  (1241.4) Adult Heart  (1099.4) Adult VirginFemale Spermatheca  (1873.8) Adult InseminatedFemale Spermatheca  (1836.5) Adult Ovary  (1286.3) Adult Testis  504.2 Adult Male Accessory Gland  (2594) Adult Carcass  (1050.2) Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System  1270.95 Larval Midgut    639.6 Larval Hindgut  1276.8 Larval Malpighian Tubules  1322.5 Larval Fat Body  1313 Larval Salivary Gland  (1750.3) Larval Trachea  1403.05 Larval Carcass  1087.675 Adult Head  1231.5 Adult Eye  (2133.65) Adult Brain  1068.8 Adult Thoracic-Abdominal Ganglion  (1822.9) Adult Crop  1205.1 Adult Midgut    724.2 Adult Hindgut  1028.7 Adult Malpighian Tubules    847.1 Adult Fat Body  1595.3 Adult Salivary Gland  1241.4 Adult Heart  1099.4 Adult VirginFemale Spermatheca  (1873.8) Adult InseminatedFemale Spermatheca  (1836.5) Adult Ovary  1286.3 Adult Testis    504.2 Adult Male Accessory Gland  (2594) Adult Carcass  1050.2 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    1270.95 Larval Midgut    639.6 Larval Hindgut    1276.8 Larval Malpighian Tubules    1322.5 Larval Fat Body    1313 Larval Salivary Gland    1750.3 Larval Trachea    1403.05 Larval Carcass    1087.675 Adult Head    1231.5 Adult Eye    2133.65 Adult Brain    1068.8 Adult Thoracic-Abdominal Ganglion    1822.9 Adult Crop    1205.1 Adult Midgut    724.2 Adult Hindgut    1028.7 Adult Malpighian Tubules    847.1 Adult Fat Body    1595.3 Adult Salivary Gland    1241.4 Adult Heart    1099.4 Adult VirginFemale Spermatheca    1873.8 Adult InseminatedFemale Spermatheca    1836.5 Adult Ovary    1286.3 Adult Testis    504.2 Adult Male Accessory Gland    2594 Adult Carcass    1050.2 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    1231.5   NA  Eye    2133.65   NA  Brain    1068.8   1270.95  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    1822.9   NA  Crop    1205.1   639.6  Midgut    724.2   1276.8  Hindgut    1028.7   1322.5  Malpighian Tubules    847.1   1313  Fat Body    1595.3   1750.3  Salivary Gland    1241.4   NA  Heart    1099.4   1403.05  Trachea    NA   NA  VirginFemale Spermatheca    1873.8   NA  InseminatedFemale Spermatheca    1836.5   NA  Ovary    1286.3   NA  Testis    504.2   NA  Male Accessory Gland    2594   1087.675  Carcass    1050.2 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    181 central nervous system, larvae L3    184 central nervous system, pupae P8    126 head, virgin 1-day female    118 head, virgin 4-day female    130 head, virgin 20-day female    152 head, mated 1-day female    102 head, mated 4-day female    120 head, mated 20-day female    110 head, mated 1-day male    152 head, mated 4-day male    156 head, mated 20-day male    163 salivary gland, larvae L3 wandering    79 salivary gland, white prepupae    299 digestive system, larvae L3 wandering    110 digestive system, 1-day adult    88 digestive system, 4-day adult    83 digestive system, 20-day adult    90 fat body, larvae L3 wandering    54 fat body, white prepupae    79 fat body, pupae P8    155 carcass, larvae L3 wandering    181 carcass, 1-day adult    72 carcass, 4-day adult    83 carcass, 20-day adult    95 ovary, virgin 4-day female    211 ovary, mated 4-day female    216 testis, mated 4-day male    121 accessory gland, mated 4-day male    158 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (181) central nervous system, larvae L3  (184) central nervous system, pupae P8  (126) head, virgin 1-day female  (118) head, virgin 4-day female  (130) head, virgin 20-day female  (152) head, mated 1-day female  (102) head, mated 4-day female  (120) head, mated 20-day female  (110) head, mated 1-day male  (152) head, mated 4-day male  (156) head, mated 20-day male  (163) salivary gland, larvae L3 wandering  (79) salivary gland, white prepupae  (299) digestive system, larvae L3 wandering  (110) digestive system, 1-day adult  (88) digestive system, 4-day adult  (83) digestive system, 20-day adult  (90) fat body, larvae L3 wandering  (54) fat body, white prepupae  (79) fat body, pupae P8  (155) carcass, larvae L3 wandering  (181) carcass, 1-day adult  (72) carcass, 4-day adult  (83) carcass, 20-day adult  (95) ovary, virgin 4-day female  (211) ovary, mated 4-day female  (216) testis, mated 4-day male  (121) accessory gland, mated 4-day male  (158) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (181) central nervous system, larvae L3  (184) central nervous system, pupae P8  (126) head, virgin 1-day female  (118) head, virgin 4-day female  (130) head, virgin 20-day female  (152) head, mated 1-day female  102 head, mated 4-day female  (120) head, mated 20-day female  (110) head, mated 1-day male  (152) head, mated 4-day male  (156) head, mated 20-day male  (163) salivary gland, larvae L3 wandering    79 salivary gland, white prepupae  (299) digestive system, larvae L3 wandering  (110) digestive system, 1-day adult    88 digestive system, 4-day adult    83 digestive system, 20-day adult    90 fat body, larvae L3 wandering    54 fat body, white prepupae    79 fat body, pupae P8  (155) carcass, larvae L3 wandering  (181) carcass, 1-day adult    72 carcass, 4-day adult    83 carcass, 20-day adult    95 ovary, virgin 4-day female  (211) ovary, mated 4-day female  (216) testis, mated 4-day male  (121) accessory gland, mated 4-day male  (158) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    181 central nervous system, larvae L3    184 central nervous system, pupae P8    126 head, virgin 1-day female    118 head, virgin 4-day female    130 head, virgin 20-day female    152 head, mated 1-day female    102 head, mated 4-day female    120 head, mated 20-day female    110 head, mated 1-day male    152 head, mated 4-day male    156 head, mated 20-day male    163 salivary gland, larvae L3 wandering    79 salivary gland, white prepupae    299 digestive system, larvae L3 wandering    110 digestive system, 1-day adult    88 digestive system, 4-day adult    83 digestive system, 20-day adult    90 fat body, larvae L3 wandering    54 fat body, white prepupae    79 fat body, pupae P8    155 carcass, larvae L3 wandering    181 carcass, 1-day adult    72 carcass, 4-day adult    83 carcass, 20-day adult    95 ovary, virgin 4-day female    211 ovary, mated 4-day female    216 testis, mated 4-day male    121 accessory gland, mated 4-day male    158 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    181 central nervous system, larvae L3    184 central nervous system, pupae P8    126 head, virgin 1-day female    118 head, virgin 4-day female    130 head, virgin 20-day female    152 head, mated 1-day female    102 head, mated 4-day female    120 head, mated 20-day female    110 head, mated 1-day male    152 head, mated 4-day male    156 head, mated 20-day male    163 salivary gland, larvae L3 wandering    79 salivary gland, white prepupae    299 digestive system, larvae L3 wandering    110 digestive system, 1-day adult    88 digestive system, 4-day adult    83 digestive system, 20-day adult    90 fat body, larvae L3 wandering    54 fat body, white prepupae    79 fat body, pupae P8    155 carcass, larvae L3 wandering    181 carcass, 1-day adult    72 carcass, 4-day adult    83 carcass, 20-day adult    95 ovary, virgin 4-day female    211 ovary, mated 4-day female    216 testis, mated 4-day male    121 accessory gland, mated 4-day male    158 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (181) central nervous system, larvae L3  (184) central nervous system, pupae P8  (126) head, virgin 1-day female  (118) head, virgin 4-day female  (130) head, virgin 20-day female  (152) head, mated 1-day female  (102) head, mated 4-day female  (120) head, mated 20-day female  (110) head, mated 1-day male  (152) head, mated 4-day male  (156) head, mated 20-day male  (163) salivary gland, larvae L3 wandering  (79) salivary gland, white prepupae  (299) digestive system, larvae L3 wandering  (110) digestive system, 1-day adult  (88) digestive system, 4-day adult  (83) digestive system, 20-day adult  (90) fat body, larvae L3 wandering  (54) fat body, white prepupae  (79) fat body, pupae P8  (155) carcass, larvae L3 wandering  (181) carcass, 1-day adult  (72) carcass, 4-day adult  (83) carcass, 20-day adult  (95) ovary, virgin 4-day female  (211) ovary, mated 4-day female  (216) testis, mated 4-day male  (121) accessory gland, mated 4-day male  (158) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (181) central nervous system, larvae L3  (184) central nervous system, pupae P8  126 head, virgin 1-day female  118 head, virgin 4-day female  130 head, virgin 20-day female  (152) head, mated 1-day female  102 head, mated 4-day female  120 head, mated 20-day female  110 head, mated 1-day male  (152) head, mated 4-day male  (156) head, mated 20-day male  (163) salivary gland, larvae L3 wandering    79 salivary gland, white prepupae  (299) digestive system, larvae L3 wandering  110 digestive system, 1-day adult    88 digestive system, 4-day adult    83 digestive system, 20-day adult    90 fat body, larvae L3 wandering    54 fat body, white prepupae    79 fat body, pupae P8  (155) carcass, larvae L3 wandering  (181) carcass, 1-day adult    72 carcass, 4-day adult    83 carcass, 20-day adult    95 ovary, virgin 4-day female  (211) ovary, mated 4-day female  (216) testis, mated 4-day male  121 accessory gland, mated 4-day male  (158) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    181 central nervous system, larvae L3    184 central nervous system, pupae P8    126 head, virgin 1-day female    118 head, virgin 4-day female    130 head, virgin 20-day female    152 head, mated 1-day female    102 head, mated 4-day female    120 head, mated 20-day female    110 head, mated 1-day male    152 head, mated 4-day male    156 head, mated 20-day male    163 salivary gland, larvae L3 wandering    79 salivary gland, white prepupae    299 digestive system, larvae L3 wandering    110 digestive system, 1-day adult    88 digestive system, 4-day adult    83 digestive system, 20-day adult    90 fat body, larvae L3 wandering    54 fat body, white prepupae    79 fat body, pupae P8    155 carcass, larvae L3 wandering    181 carcass, 1-day adult    72 carcass, 4-day adult    83 carcass, 20-day adult    95 ovary, virgin 4-day female    211 ovary, mated 4-day female    216 testis, mated 4-day male    121 accessory gland, mated 4-day male    158 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of high expression. Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    230 embryo 02-04hr    349 embryo 04-06hr    423 embryo 06-08hr    349 embryo 08-10hr    363 embryo 10-12hr    289 embryo 12-14hr    207 embryo 14-16hr    208 embryo 16-18hr    169 embryo 18-20hr    150 embryo 20-22hr    164 embryo 22-24hr    174 larva L1    211 larva L2    178 larva L3 12hr old    128 larva L3 puffstage 1-2    128 larva L3 puffstage 3-6    142 larva L3 puffstage 7-9    173 white prepupae new    178 white prepupae 12hr    180 white prepupae 24hr    193 pupae 2d postWPP    139 pupae 3d postWPP    99 pupae 4d postWPP    102 adult male 01day    123 adult male 05day    136 adult male 30day    125 adult female 01day    203 adult female 05day    208 adult female 30day    197 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (230) embryo 02-04hr  (349) embryo 04-06hr  (423) embryo 06-08hr  (349) embryo 08-10hr  (363) embryo 10-12hr  (289) embryo 12-14hr  (207) embryo 14-16hr  (208) embryo 16-18hr  (169) embryo 18-20hr  (150) embryo 20-22hr  (164) embryo 22-24hr  (174) larva L1  (211) larva L2  (178) larva L3 12hr old  (128) larva L3 puffstage 1-2  (128) larva L3 puffstage 3-6  (142) larva L3 puffstage 7-9  (173) white prepupae new  (178) white prepupae 12hr  (180) white prepupae 24hr  (193) pupae 2d postWPP  (139) pupae 3d postWPP  (99) pupae 4d postWPP  (102) adult male 01day  (123) adult male 05day  (136) adult male 30day  (125) adult female 01day  (203) adult female 05day  (208) adult female 30day  (197) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr  (230) embryo 02-04hr  (349) embryo 04-06hr  (423) embryo 06-08hr  (349) embryo 08-10hr  (363) embryo 10-12hr  (289) embryo 12-14hr  (207) embryo 14-16hr  (208) embryo 16-18hr  (169) embryo 18-20hr  (150) embryo 20-22hr  (164) embryo 22-24hr  (174) larva L1  (211) larva L2  (178) larva L3 12hr old  (128) larva L3 puffstage 1-2  (128) larva L3 puffstage 3-6  (142) larva L3 puffstage 7-9  (173) white prepupae new  (178) white prepupae 12hr  (180) white prepupae 24hr  (193) pupae 2d postWPP  (139) pupae 3d postWPP    99 pupae 4d postWPP  102 adult male 01day  (123) adult male 05day  (136) adult male 30day  (125) adult female 01day  (203) adult female 05day  (208) adult female 30day  (197) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    230 embryo 02-04hr    349 embryo 04-06hr    423 embryo 06-08hr    349 embryo 08-10hr    363 embryo 10-12hr    289 embryo 12-14hr    207 embryo 14-16hr    208 embryo 16-18hr    169 embryo 18-20hr    150 embryo 20-22hr    164 embryo 22-24hr    174 larva L1    211 larva L2    178 larva L3 12hr old    128 larva L3 puffstage 1-2    128 larva L3 puffstage 3-6    142 larva L3 puffstage 7-9    173 white prepupae new    178 white prepupae 12hr    180 white prepupae 24hr    193 pupae 2d postWPP    139 pupae 3d postWPP    99 pupae 4d postWPP    102 adult male 01day    123 adult male 05day    136 adult male 30day    125 adult female 01day    203 adult female 05day    208 adult female 30day    197 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    230 embryo 02-04hr    349 embryo 04-06hr    423 embryo 06-08hr    349 embryo 08-10hr    363 embryo 10-12hr    289 embryo 12-14hr    207 embryo 14-16hr    208 embryo 16-18hr    169 embryo 18-20hr    150 embryo 20-22hr    164 embryo 22-24hr    174 larva L1    211 larva L2    178 larva L3 12hr old    128 larva L3 puffstage 1-2    128 larva L3 puffstage 3-6    142 larva L3 puffstage 7-9    173 white prepupae new    178 white prepupae 12hr    180 white prepupae 24hr    193 pupae 2d postWPP    139 pupae 3d postWPP    99 pupae 4d postWPP    102 adult male 01day    123 adult male 05day    136 adult male 30day    125 adult female 01day    203 adult female 05day    208 adult female 30day    197 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (230) embryo 02-04hr  (349) embryo 04-06hr  (423) embryo 06-08hr  (349) embryo 08-10hr  (363) embryo 10-12hr  (289) embryo 12-14hr  (207) embryo 14-16hr  (208) embryo 16-18hr  (169) embryo 18-20hr  (150) embryo 20-22hr  (164) embryo 22-24hr  (174) larva L1  (211) larva L2  (178) larva L3 12hr old  (128) larva L3 puffstage 1-2  (128) larva L3 puffstage 3-6  (142) larva L3 puffstage 7-9  (173) white prepupae new  (178) white prepupae 12hr  (180) white prepupae 24hr  (193) pupae 2d postWPP  (139) pupae 3d postWPP  (99) pupae 4d postWPP  (102) adult male 01day  (123) adult male 05day  (136) adult male 30day  (125) adult female 01day  (203) adult female 05day  (208) adult female 30day  (197) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr  (230) embryo 02-04hr  (349) embryo 04-06hr  (423) embryo 06-08hr  (349) embryo 08-10hr  (363) embryo 10-12hr  (289) embryo 12-14hr  (207) embryo 14-16hr  (208) embryo 16-18hr  (169) embryo 18-20hr  (150) embryo 20-22hr  (164) embryo 22-24hr  (174) larva L1  (211) larva L2  (178) larva L3 12hr old  128 larva L3 puffstage 1-2  128 larva L3 puffstage 3-6  142 larva L3 puffstage 7-9  (173) white prepupae new  (178) white prepupae 12hr  (180) white prepupae 24hr  (193) pupae 2d postWPP  139 pupae 3d postWPP    99 pupae 4d postWPP  102 adult male 01day  123 adult male 05day  136 adult male 30day  125 adult female 01day  (203) adult female 05day  (208) adult female 30day  (197) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    230 embryo 02-04hr    349 embryo 04-06hr    423 embryo 06-08hr    349 embryo 08-10hr    363 embryo 10-12hr    289 embryo 12-14hr    207 embryo 14-16hr    208 embryo 16-18hr    169 embryo 18-20hr    150 embryo 20-22hr    164 embryo 22-24hr    174 larva L1    211 larva L2    178 larva L3 12hr old    128 larva L3 puffstage 1-2    128 larva L3 puffstage 3-6    142 larva L3 puffstage 7-9    173 white prepupae new    178 white prepupae 12hr    180 white prepupae 24hr    193 pupae 2d postWPP    139 pupae 3d postWPP    99 pupae 4d postWPP    102 adult male 01day    123 adult male 05day    136 adult male 30day    125 adult female 01day    203 adult female 05day    208 adult female 30day    197 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    174 Schneider line 2 Sg4    187 embryonic 1182-4H    327 embryonic GM2    237 embryonic Kc167    437 embryonic S1    239 embryonic S3    161 leg disc CME L1    219 wing disc CME-W2    145 wing disc ML-DmD8    199 wing disc ML-DmD9    322 wing disc ML-DmD16-c3    136 wing disc ML-DmD21    173 wing disc ML-DmD32    84 haltere disc ML-DmD17-c3    395 eye-antennal disc ML-DmD11    182 antennal disc ML-DmD20-c5    181 mixed discs ML-DmD4-c1    198 CNS ML-DmBG1-c1    149 CNS ML-DmBG2-c2    235 tumorous blood cells mbn2    94 ovary fGS/OSS    224 ovary OSC    96 ovary OSS    114 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (174) Schneider line 2 Sg4  (187) embryonic 1182-4H  (327) embryonic GM2  (237) embryonic Kc167  (437) embryonic S1  (239) embryonic S3  (161) leg disc CME L1  (219) wing disc CME-W2  (145) wing disc ML-DmD8  (199) wing disc ML-DmD9  (322) wing disc ML-DmD16-c3  (136) wing disc ML-DmD21  (173) wing disc ML-DmD32  (84) haltere disc ML-DmD17-c3  (395) eye-antennal disc ML-DmD11  (182) antennal disc ML-DmD20-c5  (181) mixed discs ML-DmD4-c1  (198) CNS ML-DmBG1-c1  (149) CNS ML-DmBG2-c2  (235) tumorous blood cells mbn2  (94) ovary fGS/OSS  (224) ovary OSC  (96) ovary OSS  (114) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+  (174) Schneider line 2 Sg4  (187) embryonic 1182-4H  (327) embryonic GM2  (237) embryonic Kc167  (437) embryonic S1  (239) embryonic S3  (161) leg disc CME L1  (219) wing disc CME-W2  (145) wing disc ML-DmD8  (199) wing disc ML-DmD9  (322) wing disc ML-DmD16-c3  (136) wing disc ML-DmD21  (173) wing disc ML-DmD32    84 haltere disc ML-DmD17-c3  (395) eye-antennal disc ML-DmD11  (182) antennal disc ML-DmD20-c5  (181) mixed discs ML-DmD4-c1  (198) CNS ML-DmBG1-c1  (149) CNS ML-DmBG2-c2  (235) tumorous blood cells mbn2    94 ovary fGS/OSS  (224) ovary OSC    96 ovary OSS  (114) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    174 Schneider line 2 Sg4    187 embryonic 1182-4H    327 embryonic GM2    237 embryonic Kc167    437 embryonic S1    239 embryonic S3    161 leg disc CME L1    219 wing disc CME-W2    145 wing disc ML-DmD8    199 wing disc ML-DmD9    322 wing disc ML-DmD16-c3    136 wing disc ML-DmD21    173 wing disc ML-DmD32    84 haltere disc ML-DmD17-c3    395 eye-antennal disc ML-DmD11    182 antennal disc ML-DmD20-c5    181 mixed discs ML-DmD4-c1    198 CNS ML-DmBG1-c1    149 CNS ML-DmBG2-c2    235 tumorous blood cells mbn2    94 ovary fGS/OSS    224 ovary OSC    96 ovary OSS    114 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    174 Schneider line 2 Sg4    187 embryonic 1182-4H    327 embryonic GM2    237 embryonic Kc167    437 embryonic S1    239 embryonic S3    161 leg disc CME L1    219 wing disc CME-W2    145 wing disc ML-DmD8    199 wing disc ML-DmD9    322 wing disc ML-DmD16-c3    136 wing disc ML-DmD21    173 wing disc ML-DmD32    84 haltere disc ML-DmD17-c3    395 eye-antennal disc ML-DmD11    182 antennal disc ML-DmD20-c5    181 mixed discs ML-DmD4-c1    198 CNS ML-DmBG1-c1    149 CNS ML-DmBG2-c2    235 tumorous blood cells mbn2    94 ovary fGS/OSS    224 ovary OSC    96 ovary OSS    114 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (174) Schneider line 2 Sg4  (187) embryonic 1182-4H  (327) embryonic GM2  (237) embryonic Kc167  (437) embryonic S1  (239) embryonic S3  (161) leg disc CME L1  (219) wing disc CME-W2  (145) wing disc ML-DmD8  (199) wing disc ML-DmD9  (322) wing disc ML-DmD16-c3  (136) wing disc ML-DmD21  (173) wing disc ML-DmD32  (84) haltere disc ML-DmD17-c3  (395) eye-antennal disc ML-DmD11  (182) antennal disc ML-DmD20-c5  (181) mixed discs ML-DmD4-c1  (198) CNS ML-DmBG1-c1  (149) CNS ML-DmBG2-c2  (235) tumorous blood cells mbn2  (94) ovary fGS/OSS  (224) ovary OSC  (96) ovary OSS  (114) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+  (174) Schneider line 2 Sg4  (187) embryonic 1182-4H  (327) embryonic GM2  (237) embryonic Kc167  (437) embryonic S1  (239) embryonic S3  (161) leg disc CME L1  (219) wing disc CME-W2  (145) wing disc ML-DmD8  (199) wing disc ML-DmD9  (322) wing disc ML-DmD16-c3  136 wing disc ML-DmD21  (173) wing disc ML-DmD32    84 haltere disc ML-DmD17-c3  (395) eye-antennal disc ML-DmD11  (182) antennal disc ML-DmD20-c5  (181) mixed discs ML-DmD4-c1  (198) CNS ML-DmBG1-c1  (149) CNS ML-DmBG2-c2  (235) tumorous blood cells mbn2    94 ovary fGS/OSS  (224) ovary OSC    96 ovary OSS  114 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    174 Schneider line 2 Sg4    187 embryonic 1182-4H    327 embryonic GM2    237 embryonic Kc167    437 embryonic S1    239 embryonic S3    161 leg disc CME L1    219 wing disc CME-W2    145 wing disc ML-DmD8    199 wing disc ML-DmD9    322 wing disc ML-DmD16-c3    136 wing disc ML-DmD21    173 wing disc ML-DmD32    84 haltere disc ML-DmD17-c3    395 eye-antennal disc ML-DmD11    182 antennal disc ML-DmD20-c5    181 mixed discs ML-DmD4-c1    198 CNS ML-DmBG1-c1    149 CNS ML-DmBG2-c2    235 tumorous blood cells mbn2    94 ovary fGS/OSS    224 ovary OSC    96 ovary OSS    114 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    120 cold shock, 4-day adult    91 heat shock, 4-day adult    180 Cadmium 50 mM 6 hrs, larvae L3    113 Cadmium 50 mM 12 hrs, larvae L3    122 Cadmium 50 mM 48 hrs, 4-day adult    168 Cadmium 100 mM 48 hrs, 4-day adult    200 Copper 0.5 mM 12 hrs, larvae L3    81 Copper 15 mM 48 hrs, 4-day adult    95 Zinc 5 mM 12 hrs, larvae L3    68 Zinc 4.5 mM 48 hrs, 4-day adult    105 Ethanol 2.5% 3 hrs, larvae L3    275 Ethanol 5% 3 hrs, larvae L3    122 Ethanol 10% 3 hrs, larvae L3    132 Caffeine 1.5 mg/ml 4 hrs, larvae L3    148 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    213 Caffeine 25 mg/ml 48 hrs, 4-day adult    94 Paraquat 5 mM 48 hrs, 4-day adult    206 Paraquat 10 mM 48 hrs, 4-day adult    285 Rotenone 2 μg 12 hrs, larvae L3    120 Rotenone 8 μg 12 hrs, larvae L3    122 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult  (120) cold shock, 4-day adult  (91) heat shock, 4-day adult  (180) Cadmium 50 mM 6 hrs, larvae L3  (113) Cadmium 50 mM 12 hrs, larvae L3  (122) Cadmium 50 mM 48 hrs, 4-day adult  (168) Cadmium 100 mM 48 hrs, 4-day adult  (200) Copper 0.5 mM 12 hrs, larvae L3  (81) Copper 15 mM 48 hrs, 4-day adult  (95) Zinc 5 mM 12 hrs, larvae L3  (68) Zinc 4.5 mM 48 hrs, 4-day adult  (105) Ethanol 2.5% 3 hrs, larvae L3  (275) Ethanol 5% 3 hrs, larvae L3  (122) Ethanol 10% 3 hrs, larvae L3  (132) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (148) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (213) Caffeine 25 mg/ml 48 hrs, 4-day adult  (94) Paraquat 5 mM 48 hrs, 4-day adult  (206) Paraquat 10 mM 48 hrs, 4-day adult  (285) Rotenone 2 μg 12 hrs, larvae L3  (120) Rotenone 8 μg 12 hrs, larvae L3  (122) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult  (120) cold shock, 4-day adult    91 heat shock, 4-day adult  (180) Cadmium 50 mM 6 hrs, larvae L3  (113) Cadmium 50 mM 12 hrs, larvae L3  (122) Cadmium 50 mM 48 hrs, 4-day adult  (168) Cadmium 100 mM 48 hrs, 4-day adult  (200) Copper 0.5 mM 12 hrs, larvae L3    81 Copper 15 mM 48 hrs, 4-day adult    95 Zinc 5 mM 12 hrs, larvae L3    68 Zinc 4.5 mM 48 hrs, 4-day adult  105 Ethanol 2.5% 3 hrs, larvae L3  (275) Ethanol 5% 3 hrs, larvae L3  (122) Ethanol 10% 3 hrs, larvae L3  (132) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (148) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (213) Caffeine 25 mg/ml 48 hrs, 4-day adult    94 Paraquat 5 mM 48 hrs, 4-day adult  (206) Paraquat 10 mM 48 hrs, 4-day adult  (285) Rotenone 2 μg 12 hrs, larvae L3  (120) Rotenone 8 μg 12 hrs, larvae L3  (122) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    120 cold shock, 4-day adult    91 heat shock, 4-day adult    180 Cadmium 50 mM 6 hrs, larvae L3    113 Cadmium 50 mM 12 hrs, larvae L3    122 Cadmium 50 mM 48 hrs, 4-day adult    168 Cadmium 100 mM 48 hrs, 4-day adult    200 Copper 0.5 mM 12 hrs, larvae L3    81 Copper 15 mM 48 hrs, 4-day adult    95 Zinc 5 mM 12 hrs, larvae L3    68 Zinc 4.5 mM 48 hrs, 4-day adult    105 Ethanol 2.5% 3 hrs, larvae L3    275 Ethanol 5% 3 hrs, larvae L3    122 Ethanol 10% 3 hrs, larvae L3    132 Caffeine 1.5 mg/ml 4 hrs, larvae L3    148 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    213 Caffeine 25 mg/ml 48 hrs, 4-day adult    94 Paraquat 5 mM 48 hrs, 4-day adult    206 Paraquat 10 mM 48 hrs, 4-day adult    285 Rotenone 2 μg 12 hrs, larvae L3    120 Rotenone 8 μg 12 hrs, larvae L3    122 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    120 cold shock, 4-day adult    91 heat shock, 4-day adult    180 Cadmium 50 mM 6 hrs, larvae L3    113 Cadmium 50 mM 12 hrs, larvae L3    122 Cadmium 50 mM 48 hrs, 4-day adult    168 Cadmium 100 mM 48 hrs, 4-day adult    200 Copper 0.5 mM 12 hrs, larvae L3    81 Copper 15 mM 48 hrs, 4-day adult    95 Zinc 5 mM 12 hrs, larvae L3    68 Zinc 4.5 mM 48 hrs, 4-day adult    105 Ethanol 2.5% 3 hrs, larvae L3    275 Ethanol 5% 3 hrs, larvae L3    122 Ethanol 10% 3 hrs, larvae L3    132 Caffeine 1.5 mg/ml 4 hrs, larvae L3    148 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    213 Caffeine 25 mg/ml 48 hrs, 4-day adult    94 Paraquat 5 mM 48 hrs, 4-day adult    206 Paraquat 10 mM 48 hrs, 4-day adult    285 Rotenone 2 μg 12 hrs, larvae L3    120 Rotenone 8 μg 12 hrs, larvae L3    122 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult  (120) cold shock, 4-day adult  (91) heat shock, 4-day adult  (180) Cadmium 50 mM 6 hrs, larvae L3  (113) Cadmium 50 mM 12 hrs, larvae L3  (122) Cadmium 50 mM 48 hrs, 4-day adult  (168) Cadmium 100 mM 48 hrs, 4-day adult  (200) Copper 0.5 mM 12 hrs, larvae L3  (81) Copper 15 mM 48 hrs, 4-day adult  (95) Zinc 5 mM 12 hrs, larvae L3  (68) Zinc 4.5 mM 48 hrs, 4-day adult  (105) Ethanol 2.5% 3 hrs, larvae L3  (275) Ethanol 5% 3 hrs, larvae L3  (122) Ethanol 10% 3 hrs, larvae L3  (132) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (148) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (213) Caffeine 25 mg/ml 48 hrs, 4-day adult  (94) Paraquat 5 mM 48 hrs, 4-day adult  (206) Paraquat 10 mM 48 hrs, 4-day adult  (285) Rotenone 2 μg 12 hrs, larvae L3  (120) Rotenone 8 μg 12 hrs, larvae L3  (122) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult  120 cold shock, 4-day adult    91 heat shock, 4-day adult  (180) Cadmium 50 mM 6 hrs, larvae L3  113 Cadmium 50 mM 12 hrs, larvae L3  122 Cadmium 50 mM 48 hrs, 4-day adult  (168) Cadmium 100 mM 48 hrs, 4-day adult  (200) Copper 0.5 mM 12 hrs, larvae L3    81 Copper 15 mM 48 hrs, 4-day adult    95 Zinc 5 mM 12 hrs, larvae L3    68 Zinc 4.5 mM 48 hrs, 4-day adult  105 Ethanol 2.5% 3 hrs, larvae L3  (275) Ethanol 5% 3 hrs, larvae L3  122 Ethanol 10% 3 hrs, larvae L3  132 Caffeine 1.5 mg/ml 4 hrs, larvae L3  (148) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (213) Caffeine 25 mg/ml 48 hrs, 4-day adult    94 Paraquat 5 mM 48 hrs, 4-day adult  (206) Paraquat 10 mM 48 hrs, 4-day adult  (285) Rotenone 2 μg 12 hrs, larvae L3  120 Rotenone 8 μg 12 hrs, larvae L3  122 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    120 cold shock, 4-day adult    91 heat shock, 4-day adult    180 Cadmium 50 mM 6 hrs, larvae L3    113 Cadmium 50 mM 12 hrs, larvae L3    122 Cadmium 50 mM 48 hrs, 4-day adult    168 Cadmium 100 mM 48 hrs, 4-day adult    200 Copper 0.5 mM 12 hrs, larvae L3    81 Copper 15 mM 48 hrs, 4-day adult    95 Zinc 5 mM 12 hrs, larvae L3    68 Zinc 4.5 mM 48 hrs, 4-day adult    105 Ethanol 2.5% 3 hrs, larvae L3    275 Ethanol 5% 3 hrs, larvae L3    122 Ethanol 10% 3 hrs, larvae L3    132 Caffeine 1.5 mg/ml 4 hrs, larvae L3    148 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    213 Caffeine 25 mg/ml 48 hrs, 4-day adult    94 Paraquat 5 mM 48 hrs, 4-day adult    206 Paraquat 10 mM 48 hrs, 4-day adult    285 Rotenone 2 μg 12 hrs, larvae L3    120 Rotenone 8 μg 12 hrs, larvae L3    122 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_17 mE1_20_mRNA_expression_cluster_10
External Data & Images
Linkouts	BDGP expression data • RE21692 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0036258 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG5642-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable, with Scer\GAL4pnr-MD237 CG5642GD14875 Phenotype manifest in Allele
Classical Alleles ( 1 )
For All Classical Alleles Show
Allele of CG5642 Class Mutagen Stocks Known lesion CG5642CPTI003526 piggyBac transposase 0 Yes
Alleles Carried on Transgenic Constructs ( 2 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG5642 Class Mutagen Stocks Known lesion CG5642GD14875 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes CG5642KK102071 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes
Aneuploid Aberrations
Disrupted in	Df(3L)Exel6116 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD14875} NA P{KK102071} NA
Insertions
	Type of insertions Name Expression data miscellaneous insertions PBac{768.FSVS-0}CG5642CPTI003526 NA
Gene Ontology: Function, Process & Cellular Component ( 4 unique terms )
Terms Based on Experimental Evidence ( 1 term )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
neuron projection morphogenesis inferred from mutant phenotype (Sepp et al., 2008)
Cellular Component ( 0 terms)
Terms Based on Predictions or Assertions ( 3 terms )
Molecular Function
CV term Evidence References
contributes_to translation initiation factor activity inferred from sequence or structural similarity with human EIF3L (Curators, 2008--)
Biological Process
CV term Evidence References
translational initiation inferred from sequence or structural similarity with human EIF3L (Curators, 2008--)
Cellular Component
CV term Evidence References
eukaryotic translation initiation factor 3 complex inferred from sequence or structural similarity with human EIF3L (Curators, 2008--)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
protein-protein
Interacting group Assay References
CG5642 - CG10005 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - CG10026 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - CG10306 experimental knowledge based (Guruharsha et al., 2011) CG5642 - CG10465 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - CG10909 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - CG1105 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - CG11188 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - CG11208 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - CG11437 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - CG11679 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - CG12519 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - CG12576 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - CG12725 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - CG12818 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - CG12883 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - CG12920 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - CG13284 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - CG1340 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - CG13532 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - CG13950 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - CG14020 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - CG14071 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - CG14153 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - CG14572 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - CG14598 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - CG14615 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - CG14818 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - CG1492 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - CG15044 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - CG17010 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - CG17162 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - CG17776 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - CG1888 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - CG2950 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - CG31156 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - CG31798 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - CG3198 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - CG32564 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - CG32850 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - CG33156 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - CG33937 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - CG3542 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - CG3819 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - CG42258 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - CG43897 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - CG4666 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - CG4810 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - CG4866 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - CG4962 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - CG5028 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - CG6218 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - CG6629 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - CG6763 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - CG6767 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - CG7164 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - CG7272 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - CG7339 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - CG7550 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - CG7686 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - CG8636 experimental knowledge based (Guruharsha et al., 2011) CG5642 - CG8671 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - CG9769 experimental knowledge based (Guruharsha et al., 2011) CG5642 - CG9945 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - CHOp24 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - CR18854 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - CkIIβ anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - Cpr11A anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - Cpr23B anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - Csat anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - Dhod anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - Dip3 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - Doc1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - E(spl)m5-HLH anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - Fas3 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - GABPI anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - GM130 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - GstE14 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - GstE6 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - Gαs anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - HDAC6 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - Hcs anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - Int6 experimental knowledge based (Guruharsha et al., 2011) CG5642 - Jon44E anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - Mp20 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - Nmdar1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - Obp44a anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - Obp56e anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - Obp83g anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - Pdf anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - Pis anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - Pnn anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - Pp2B-14D anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - Pp4-19C anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - Prosβ5 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - Pu anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - R anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - Rbf anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - Rcd1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - RfC3 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - Rheb anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - RpLP0 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - Rpb5 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - Rpn9 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - Rpt4R anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - Sk1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - SoxN anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - Spf45 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - Stat92E anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - Su(var)2-10 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - Su(var)3-3 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - Tango7 experimental knowledge based (Guruharsha et al., 2011) CG5642 - Vinc anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - Wsck anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - ana2 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - caup anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - dac anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - dah anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - eIF-3p40 experimental knowledge based (Guruharsha et al., 2011) CG5642 - eIF-3p66 experimental knowledge based (Guruharsha et al., 2011) CG5642 - eIF3-S10 experimental knowledge based (Guruharsha et al., 2011) CG5642 - eIF3-S8 experimental knowledge based (Guruharsha et al., 2011) CG5642 - eIF3-S9 experimental knowledge based (Guruharsha et al., 2011) CG5642 - fz anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - gk anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - grk anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - hyx anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - l(2)35Bc anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - sax anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - stai anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - sunz anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - swi2 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - vir-1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - wds anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG5642 - γTub37C anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23)
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG5642 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 64740 DroID - A comprehensive database of gene and protein interactions. • FBgn0036258 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 39386
Orthologs
OrthoDB Orthologs (38) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6QVCXN Dipteran inclusive ortholog search EOG669R31 Insect inclusive ortholog search EOG6K3JRF Arthropod inclusive ortholog search EOG6VX0MB Metazoa inclusive ortholog search EOG6PS5HT
Orthologs in Drosophila Species (EOG6QVCXN)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\CG5642     Drosophila simulans   Dsim\GD12745 Y   Drosophila sechellia   Dsec\GM24677 Y   Drosophila erecta   Dere\GG13851 Y   Drosophila yakuba   Dyak\GE20146 Y   Drosophila ananassae   Dana\GF25000 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA19025 Y   Drosophila persimilis   Dper\GL25016 Y   Drosophila willistoni   Dwil\GK20774 Y   Drosophila virilis   Dvir\GJ13043 Y   Drosophila mojavensis   Dmoj\GI12903 Y   Drosophila grimshawi   Dgri\GH15308 Y
Orthologs in non-Drosophila Dipterans (EOG669R31)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL014715   Aedes aegypti Yellow fever mosquito  Aaeg\AAEL009617   Anopheles gambiae Malaria mosquito  Agam\AGAP006130   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ009242
Orthologs in non-Dipteran Insects (EOG6K3JRF)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\LOC552056   Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG018301   Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH20796   Atta cephalotes Leafcutter ant  Acep\ACEP13765   Camponotus floridanus Florida carpenter ant  Cflo\CFLO20686   Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL18427   Linepithema humile Argentine ant  Lhum\LH22722   Pogonomyrmex barbatus Red harvester ant  Pbar\PB17821   Acyrthosiphon pisum Pea aphid  Apim\ACYPI001686   Bombyx mori Silkmoth  Bmor\BGIBMGA012126   Pediculus humanus Human body louse  Phum\PHUM182170   Tribolium castaneum Red flour beetle  Tcas\TC003034
Orthologs in non-Insect Arthropods (EOG6VX0MB)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\HA   Ixodes scapularis Deer tick  Isca\ISCW023584
Orthologs in non-Arthropod Metazoa (EOG6PS5HT)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Caenorhabditis elegans Nematode  Cele\eif-3.L   Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_021449gn   Danio rerio Zebrafish  Drer\eif3l   Xenopus tropicalis Western clawed frog  Xtro\eif3l   Gallus gallus Domestic chicken  Ggal\EIF3EIP   Mus musculus House mouse  Mmus\Eif3l   Rattus norvegicus Norway rat  Rnor\Eif3s6ip   Homo sapiens Human  Hsap\EIF3L
Human Orthologs (1)
Gene OMIM HGNC Hsap\EIF3L
AAA Orthologs (11) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD12745 Drosophila sechellia Dsec\GM24677 Drosophila erecta Dere\GG13851 Drosophila yakuba Dyak\GE20146 Drosophila ananassae Dana\GF25000 Drosophila pseudoobscura pseudoobscura Dpse\GA19025 Drosophila persimilis Dper\GL25016 Drosophila willistoni Dwil\GK20774 Drosophila virilis Dvir\GJ13043 Drosophila mojavensis Dmoj\GI12903 Drosophila grimshawi Dgri\GH15308
Stocks & Reagents
Stocks Listed in FlyBase ( 3 )
VDRC	v107267 P{KK102071}VIE-260B v46592 w1118; P{GD14875}v46592 v46594 w1118; P{GD14875}v46594
Genomic Clones ( 2 )
	BACR05P17 BACR14K14 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 138 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	RE21692
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT31815 GH03962 GH06447 GH13822 GH14310 GH15056 GH15925 GH28519 GM01220 GM02940 GM03180 GM08852 GM09969 GM12228 GM13477 GM18651 GM19107 GM21129 HL04783 HL04791 LD03077 LD03289 LD04609 LD06672 LD06873 LD08112 LD08285 LD09644 LD11635 LD11949 LD12793 LD13688 LD13725 LD17016 LD19102 LD21181 LD22869 LD23312 LD32650 LD32710 LD37076 LD40609 LD40910 LD42167 LD47225 LD47664 LP09495 LP10762 LP16494 LP16826 RE15329 RE17979 RE22289 RE26179 RE28104 RE36344 RE36546 RE49480 RE51380 RE58694 RE60155 RE62431 RE70652 RH66391 RH67852 SD04076 SD12724 SD13966 SD23854
Other clones	62370 72076 77683 276700 569143 569278 571123 576526 AT10651 CK01.99A.H3 Dmel_dig_004388_0619_0428 Dmel_dig_006619_0656_0451 Dmel_dig_019051_0646_3574 Dmel_dig_019115_0677_2245 Dmel_neb_007829_0149_1906 Dmel_neb_013717_0088_0766 EK186101 EK187757 EK200354 EK303410 EN14625 EN14861 EN16128 EN17845 FGH119D04 FGH127D07 RP003032475 RP003039253 RP003041322 RP003059910 RP003095285 RP003100675 RP003101021 RP003110999 RP003122008 RP003136522 RP003179909 RP003206774 RP003207223 RP003213707 RP003228608 RP003229393 RP003229412 RP003239317 RP003276951 RP003284201 RP003303090 RP003303500 RP003328786 RP003382306 RP003385439 RP003418431 RP003452105 RP003489841 RP003494582 RP003505275 RP003513597 RP003531372 RP003538771 RP003560560 RP003561180 RP003574100 RP003633865 RP003649763 RP003671651 RP003675750 UT01879 UUGC0205
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0036258 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 39386
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_140296 RefSeq (Proteins) • NP_648553 DDBJ / EMBL / GenBank • AAF49952 AAL90345 AY089607 BI215325 Entrez Gene - A searchable database of RefSeq genes. • 39386 UniProtKB/Swiss-Prot • Q9VTU4
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Translation initiation factor 3 complex subunit L (IPR019382) BDGP expression data - Patterns of gene expression in Drosophila embryogenesis • RE21692
Linkouts
	BioGRID - A database of protein and genetic interactions • 64740 DroID - A comprehensive database of gene and protein interactions. • FBgn0036258 DRSC - Results from RNAi screens. • FBgn0036258 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0036258 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG5642-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0036258 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 39386 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 39386 modMine - Data generated by the modENCODE project. • FBgn0036258
Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	CG5642 (Stuart et al., 2007, Yi et al., 2008, Keleman et al., 2009.8.5, Gandhi et al., 2007, Cammarato et al., 2011, Sepp et al., 2008)
Name Synonym
Secondary FlyBase IDs
References ( 21 )
Generate a list of	All references relating to this gene ( 21 )
List References by type	Research paper  ( 4 ) Supplementary material  ( 7 ) Personal communication to FlyBase  ( 6 ) FlyBase analysis  ( 2 ) Website  ( 1 )
Recent research papers (0)
	All research papers listed in FlyBase were published before 2011 Show research papers ...