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Gene Dmel\CG10984

General Information
Symbol	Dmel\CG10984	Species	D. melanogaster
Name		Annotation symbol	CG10984
Feature type	protein_coding_gene	FlyBase ID	FBgn0036305
Gene Model Status	Current	Stock availability	6 publicly available
Genomic Location
Chromosome (arm)	3L	Recombination map
Cytogenetic map	69E1-69E1	Sequence location	3L:12,743,219..12,746,502 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG10984 (FBgn0036305). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 7 alleles are reported. No phenotypic data is available. It has 4 annotated transcripts and 4 annotated polypeptides. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed at stages throughout embryogenesis, during late larval stages, at stages throughout the pupal period, in stages of adults of both sexes. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult eye, larval/adult central nervous system, adult crop, larval Malpighian tubules, larval/adult salivary gland, larval trachea, adult ovary, adult male reproductive system, larval carcass. Comments on Affy2 ProbeSet: ProbeSet 1628892_s_at completely aligns to an exonic region common to each of the 3 FlyBase-annotated transcript isoforms of CG10984. Gene sequence location is 3L:12743219..12746502.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 69E1-69E1   Limits computationally determined from genome sequence between P{PZ}l(3)0508805088 and P{PZ}l(3)0692406924
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG10984 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.45 Low-frequency RNA-seq exon junction(s) not annotated. Annotated transcripts do not represent all possible combinations of alternative exons and/or alternative promoters.
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG10984-RA FBtr0075920  NM_140336   2267   640 CG10984-RB FBtr0075921  NM_168510   2321   658 CG10984-RC FBtr0075919  NM_168511   2254   640 CG10984-RD FBtr0331554  NM_001274853   2285   640
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG10984-PA   FBpp0075652   71.2   640   6.95     NP_648593   AAF49889 CG10984-PB   FBpp0075653   73.2   658   7.01     NP_729823   AAN11854 CG10984-PC   FBpp0075651   71.2   640   6.95     NP_729824   AAN11855 CG10984-PD   FBpp0303944   71.2   640   6.95     NP_001261782   AGB94475
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA264023   AA540157   AE014296 AAF49889   AE014296 AAN11854   AE014296 AAN11855   AE014296 AGB94475   AW941641   AY069368 AAL39513   BE662244   BF490722   BF506185   BI167938   BI214324   BI215018   BI215446   BI370674   BI374262   BI376105   BI482534   BI635074   BI638831   BT126397   CA804056   CO281628   CO301497   CO339483   CZ470756   CZ487966   EC078775   EC199470   EC223212   EC256738   EV584554   GH943673   GH946822   GH950051   GH957268   GH960592   GH969242   GH976904   GH980084   GH983037   GH983431   GH984787
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q8IQI3 Q8T0E7
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
in situ Stage Tissue/Position (including subcellular localization) Reference embryonic stage 1 -- 3   organism   (Fisher et al., 2012) Comment:maternally deposited embryonic stage 4 -- 6   organism | ubiquitous   (Fisher et al., 2012) embryonic stage 7 -- 8   organism | ubiquitous   (Fisher et al., 2012) embryonic stage 9 -- 10   organism | faint & ubiquitous   (Fisher et al., 2012) organism | ubiquitous   (Fisher et al., 2012) embryonic stage 11 -- 12   anterior midgut primordium   (Fisher et al., 2012) head mesoderm   (Fisher et al., 2012) organism | faint & ubiquitous   (Fisher et al., 2012) organism | ubiquitous   (Fisher et al., 2012) posterior midgut primordium   (Fisher et al., 2012) trunk mesoderm   (Fisher et al., 2012) embryonic stage 13 -- 16   organism | faint & ubiquitous   (Fisher et al., 2012) organism | ubiquitous   (Fisher et al., 2012)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult eye, larval/adult central nervous system, adult crop, larval Malpighian tubules, larval/adult salivary gland, larval trachea, adult ovary, adult male reproductive system, larval carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    242.45 Larval Midgut    54.3 Larval Hindgut    95.6 Larval Malpighian Tubules    129 Larval Fat Body    72.3 Larval Salivary Gland    169.5 Larval Trachea    141.475 Larval Carcass    120.675 Adult Head    97.1 Adult Eye    111.8 Adult Brain    265.9 Adult Thoracic-Abdominal Ganglion    292.1 Adult Crop    132.1 Adult Midgut    51.9 Adult Hindgut    81.5 Adult Malpighian Tubules    63.7 Adult Fat Body    64.5 Adult Salivary Gland    138.7 Adult Heart    80.9 Adult VirginFemale Spermatheca    56.1 Adult InseminatedFemale Spermatheca    64.7 Adult Ovary    189.8 Adult Testis    296.4 Adult Male Accessory Gland    122.1 Adult Carcass    73.3 Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    242.45 Larval Midgut    54.3 Larval Hindgut    95.6 Larval Malpighian Tubules    129 Larval Fat Body    72.3 Larval Salivary Gland    169.5 Larval Trachea    141.475 Larval Carcass    120.675 Adult Head    97.1 Adult Eye    111.8 Adult Brain    265.9 Adult Thoracic-Abdominal Ganglion    292.1 Adult Crop    132.1 Adult Midgut    51.9 Adult Hindgut    81.5 Adult Malpighian Tubules    63.7 Adult Fat Body    64.5 Adult Salivary Gland    138.7 Adult Heart    80.9 Adult VirginFemale Spermatheca    56.1 Adult InseminatedFemale Spermatheca    64.7 Adult Ovary    189.8 Adult Testis    296.4 Adult Male Accessory Gland    122.1 Adult Carcass    73.3 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    242.45 Larval Midgut    54.3 Larval Hindgut    95.6 Larval Malpighian Tubules    129 Larval Fat Body    72.3 Larval Salivary Gland    169.5 Larval Trachea    141.475 Larval Carcass    120.675 Adult Head    97.1 Adult Eye    111.8 Adult Brain    265.9 Adult Thoracic-Abdominal Ganglion    292.1 Adult Crop    132.1 Adult Midgut    51.9 Adult Hindgut    81.5 Adult Malpighian Tubules    63.7 Adult Fat Body    64.5 Adult Salivary Gland    138.7 Adult Heart    80.9 Adult VirginFemale Spermatheca    56.1 Adult InseminatedFemale Spermatheca    64.7 Adult Ovary    189.8 Adult Testis    296.4 Adult Male Accessory Gland    122.1 Adult Carcass    73.3 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    242.45 Larval Midgut    54.3 Larval Hindgut    95.6 Larval Malpighian Tubules    129 Larval Fat Body    72.3 Larval Salivary Gland    169.5 Larval Trachea    141.475 Larval Carcass    120.675 Adult Head    97.1 Adult Eye    111.8 Adult Brain    265.9 Adult Thoracic-Abdominal Ganglion    292.1 Adult Crop    132.1 Adult Midgut    51.9 Adult Hindgut    81.5 Adult Malpighian Tubules    63.7 Adult Fat Body    64.5 Adult Salivary Gland    138.7 Adult Heart    80.9 Adult VirginFemale Spermatheca    56.1 Adult InseminatedFemale Spermatheca    64.7 Adult Ovary    189.8 Adult Testis    296.4 Adult Male Accessory Gland    122.1 Adult Carcass    73.3 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    242.45 Larval Midgut    54.3 Larval Hindgut    95.6 Larval Malpighian Tubules    129 Larval Fat Body    72.3 Larval Salivary Gland    169.5 Larval Trachea    141.475 Larval Carcass    120.675 Adult Head    97.1 Adult Eye    111.8 Adult Brain    265.9 Adult Thoracic-Abdominal Ganglion    292.1 Adult Crop    132.1 Adult Midgut    51.9 Adult Hindgut    81.5 Adult Malpighian Tubules    63.7 Adult Fat Body    64.5 Adult Salivary Gland    138.7 Adult Heart    80.9 Adult VirginFemale Spermatheca    56.1 Adult InseminatedFemale Spermatheca    64.7 Adult Ovary    189.8 Adult Testis    296.4 Adult Male Accessory Gland    122.1 Adult Carcass    73.3 Expression Level Scale  None   Low   Moderate   High  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    242.45 Larval Midgut    54.3 Larval Hindgut    95.6 Larval Malpighian Tubules    129 Larval Fat Body    72.3 Larval Salivary Gland    169.5 Larval Trachea    141.475 Larval Carcass    120.675 Adult Head    97.1 Adult Eye    111.8 Adult Brain    265.9 Adult Thoracic-Abdominal Ganglion    292.1 Adult Crop    132.1 Adult Midgut    51.9 Adult Hindgut    81.5 Adult Malpighian Tubules    63.7 Adult Fat Body    64.5 Adult Salivary Gland    138.7 Adult Heart    80.9 Adult VirginFemale Spermatheca    56.1 Adult InseminatedFemale Spermatheca    64.7 Adult Ovary    189.8 Adult Testis    296.4 Adult Male Accessory Gland    122.1 Adult Carcass    73.3 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    242.45 Larval Midgut    54.3 Larval Hindgut    95.6 Larval Malpighian Tubules    129 Larval Fat Body    72.3 Larval Salivary Gland    169.5 Larval Trachea    141.475 Larval Carcass    120.675 Adult Head    97.1 Adult Eye    111.8 Adult Brain    265.9 Adult Thoracic-Abdominal Ganglion    292.1 Adult Crop    132.1 Adult Midgut    51.9 Adult Hindgut    81.5 Adult Malpighian Tubules    63.7 Adult Fat Body    64.5 Adult Salivary Gland    138.7 Adult Heart    80.9 Adult VirginFemale Spermatheca    56.1 Adult InseminatedFemale Spermatheca    64.7 Adult Ovary    189.8 Adult Testis    296.4 Adult Male Accessory Gland    122.1 Adult Carcass    73.3 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    242.45 Larval Midgut    54.3 Larval Hindgut    95.6 Larval Malpighian Tubules    129 Larval Fat Body    72.3 Larval Salivary Gland    169.5 Larval Trachea    141.475 Larval Carcass    120.675 Adult Head    97.1 Adult Eye    111.8 Adult Brain    265.9 Adult Thoracic-Abdominal Ganglion    292.1 Adult Crop    132.1 Adult Midgut    51.9 Adult Hindgut    81.5 Adult Malpighian Tubules    63.7 Adult Fat Body    64.5 Adult Salivary Gland    138.7 Adult Heart    80.9 Adult VirginFemale Spermatheca    56.1 Adult InseminatedFemale Spermatheca    64.7 Adult Ovary    189.8 Adult Testis    296.4 Adult Male Accessory Gland    122.1 Adult Carcass    73.3 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    97.1   NA  Eye    111.8   NA  Brain    265.9   242.45  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    292.1   NA  Crop    132.1   54.3  Midgut    51.9   95.6  Hindgut    81.5   129  Malpighian Tubules    63.7   72.3  Fat Body    64.5   169.5  Salivary Gland    138.7   NA  Heart    80.9   141.475  Trachea    NA   NA  VirginFemale Spermatheca    56.1   NA  InseminatedFemale Spermatheca    64.7   NA  Ovary    189.8   NA  Testis    296.4   NA  Male Accessory Gland    122.1   120.675  Carcass    73.3 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    43 central nervous system, larvae L3    53 central nervous system, pupae P8    60 head, virgin 1-day female    19 head, virgin 4-day female    22 head, virgin 20-day female    13 head, mated 1-day female    20 head, mated 4-day female    20 head, mated 20-day female    14 head, mated 1-day male    29 head, mated 4-day male    34 head, mated 20-day male    31 salivary gland, larvae L3 wandering    9 salivary gland, white prepupae    34 digestive system, larvae L3 wandering    20 digestive system, 1-day adult    9 digestive system, 4-day adult    10 digestive system, 20-day adult    7 fat body, larvae L3 wandering    5 fat body, white prepupae    24 fat body, pupae P8    25 carcass, larvae L3 wandering    45 carcass, 1-day adult    10 carcass, 4-day adult    13 carcass, 20-day adult    12 ovary, virgin 4-day female    48 ovary, mated 4-day female    44 testis, mated 4-day male    36 accessory gland, mated 4-day male    11 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (43) central nervous system, larvae L3  (53) central nervous system, pupae P8  (60) head, virgin 1-day female    19 head, virgin 4-day female    22 head, virgin 20-day female    13 head, mated 1-day female    20 head, mated 4-day female    20 head, mated 20-day female    14 head, mated 1-day male  (29) head, mated 4-day male  (34) head, mated 20-day male  (31) salivary gland, larvae L3 wandering    9 salivary gland, white prepupae  (34) digestive system, larvae L3 wandering    20 digestive system, 1-day adult    9 digestive system, 4-day adult    10 digestive system, 20-day adult    7 fat body, larvae L3 wandering    5 fat body, white prepupae    24 fat body, pupae P8    25 carcass, larvae L3 wandering  (45) carcass, 1-day adult    10 carcass, 4-day adult    13 carcass, 20-day adult    12 ovary, virgin 4-day female  (48) ovary, mated 4-day female  (44) testis, mated 4-day male  (36) accessory gland, mated 4-day male    11 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    43 central nervous system, larvae L3    53 central nervous system, pupae P8    60 head, virgin 1-day female    19 head, virgin 4-day female    22 head, virgin 20-day female    13 head, mated 1-day female    20 head, mated 4-day female    20 head, mated 20-day female    14 head, mated 1-day male    29 head, mated 4-day male    34 head, mated 20-day male    31 salivary gland, larvae L3 wandering    9 salivary gland, white prepupae    34 digestive system, larvae L3 wandering    20 digestive system, 1-day adult    9 digestive system, 4-day adult    10 digestive system, 20-day adult    7 fat body, larvae L3 wandering    5 fat body, white prepupae    24 fat body, pupae P8    25 carcass, larvae L3 wandering    45 carcass, 1-day adult    10 carcass, 4-day adult    13 carcass, 20-day adult    12 ovary, virgin 4-day female    48 ovary, mated 4-day female    44 testis, mated 4-day male    36 accessory gland, mated 4-day male    11 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    43 central nervous system, larvae L3    53 central nervous system, pupae P8    60 head, virgin 1-day female    19 head, virgin 4-day female    22 head, virgin 20-day female    13 head, mated 1-day female    20 head, mated 4-day female    20 head, mated 20-day female    14 head, mated 1-day male    29 head, mated 4-day male    34 head, mated 20-day male    31 salivary gland, larvae L3 wandering    9 salivary gland, white prepupae    34 digestive system, larvae L3 wandering    20 digestive system, 1-day adult    9 digestive system, 4-day adult    10 digestive system, 20-day adult    7 fat body, larvae L3 wandering    5 fat body, white prepupae    24 fat body, pupae P8    25 carcass, larvae L3 wandering    45 carcass, 1-day adult    10 carcass, 4-day adult    13 carcass, 20-day adult    12 ovary, virgin 4-day female    48 ovary, mated 4-day female    44 testis, mated 4-day male    36 accessory gland, mated 4-day male    11 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    43 central nervous system, larvae L3    53 central nervous system, pupae P8    60 head, virgin 1-day female    19 head, virgin 4-day female    22 head, virgin 20-day female    13 head, mated 1-day female    20 head, mated 4-day female    20 head, mated 20-day female    14 head, mated 1-day male    29 head, mated 4-day male    34 head, mated 20-day male    31 salivary gland, larvae L3 wandering    9 salivary gland, white prepupae    34 digestive system, larvae L3 wandering    20 digestive system, 1-day adult    9 digestive system, 4-day adult    10 digestive system, 20-day adult    7 fat body, larvae L3 wandering    5 fat body, white prepupae    24 fat body, pupae P8    25 carcass, larvae L3 wandering    45 carcass, 1-day adult    10 carcass, 4-day adult    13 carcass, 20-day adult    12 ovary, virgin 4-day female    48 ovary, mated 4-day female    44 testis, mated 4-day male    36 accessory gland, mated 4-day male    11 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (43) central nervous system, larvae L3  (53) central nervous system, pupae P8  (60) head, virgin 1-day female    19 head, virgin 4-day female    22 head, virgin 20-day female    13 head, mated 1-day female    20 head, mated 4-day female    20 head, mated 20-day female    14 head, mated 1-day male  29 head, mated 4-day male  (34) head, mated 20-day male  31 salivary gland, larvae L3 wandering    9 salivary gland, white prepupae  (34) digestive system, larvae L3 wandering    20 digestive system, 1-day adult    9 digestive system, 4-day adult    10 digestive system, 20-day adult    7 fat body, larvae L3 wandering    5 fat body, white prepupae    24 fat body, pupae P8    25 carcass, larvae L3 wandering  (45) carcass, 1-day adult    10 carcass, 4-day adult    13 carcass, 20-day adult    12 ovary, virgin 4-day female  (48) ovary, mated 4-day female  (44) testis, mated 4-day male  (36) accessory gland, mated 4-day male    11 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    43 central nervous system, larvae L3    53 central nervous system, pupae P8    60 head, virgin 1-day female    19 head, virgin 4-day female    22 head, virgin 20-day female    13 head, mated 1-day female    20 head, mated 4-day female    20 head, mated 20-day female    14 head, mated 1-day male    29 head, mated 4-day male    34 head, mated 20-day male    31 salivary gland, larvae L3 wandering    9 salivary gland, white prepupae    34 digestive system, larvae L3 wandering    20 digestive system, 1-day adult    9 digestive system, 4-day adult    10 digestive system, 20-day adult    7 fat body, larvae L3 wandering    5 fat body, white prepupae    24 fat body, pupae P8    25 carcass, larvae L3 wandering    45 carcass, 1-day adult    10 carcass, 4-day adult    13 carcass, 20-day adult    12 ovary, virgin 4-day female    48 ovary, mated 4-day female    44 testis, mated 4-day male    36 accessory gland, mated 4-day male    11 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    43 central nervous system, larvae L3    53 central nervous system, pupae P8    60 head, virgin 1-day female    19 head, virgin 4-day female    22 head, virgin 20-day female    13 head, mated 1-day female    20 head, mated 4-day female    20 head, mated 20-day female    14 head, mated 1-day male    29 head, mated 4-day male    34 head, mated 20-day male    31 salivary gland, larvae L3 wandering    9 salivary gland, white prepupae    34 digestive system, larvae L3 wandering    20 digestive system, 1-day adult    9 digestive system, 4-day adult    10 digestive system, 20-day adult    7 fat body, larvae L3 wandering    5 fat body, white prepupae    24 fat body, pupae P8    25 carcass, larvae L3 wandering    45 carcass, 1-day adult    10 carcass, 4-day adult    13 carcass, 20-day adult    12 ovary, virgin 4-day female    48 ovary, mated 4-day female    44 testis, mated 4-day male    36 accessory gland, mated 4-day male    11 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed at stages throughout embryogenesis, during late larval stages, at stages throughout the pupal period, in stages of adults of both sexes. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    33 embryo 02-04hr    38 embryo 04-06hr    33 embryo 06-08hr    36 embryo 08-10hr    36 embryo 10-12hr    30 embryo 12-14hr    29 embryo 14-16hr    20 embryo 16-18hr    21 embryo 18-20hr    17 embryo 20-22hr    19 embryo 22-24hr    21 larva L1    10 larva L2    9 larva L3 12hr old    7 larva L3 puffstage 1-2    11 larva L3 puffstage 3-6    18 larva L3 puffstage 7-9    26 white prepupae new    29 white prepupae 12hr    32 white prepupae 24hr    37 pupae 2d postWPP    34 pupae 3d postWPP    21 pupae 4d postWPP    13 adult male 01day    16 adult male 05day    20 adult male 30day    18 adult female 01day    12 adult female 05day    20 adult female 30day    19 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (33) embryo 02-04hr  (38) embryo 04-06hr  (33) embryo 06-08hr  (36) embryo 08-10hr  (36) embryo 10-12hr  (30) embryo 12-14hr  (29) embryo 14-16hr    20 embryo 16-18hr    21 embryo 18-20hr    17 embryo 20-22hr    19 embryo 22-24hr    21 larva L1    10 larva L2    9 larva L3 12hr old    7 larva L3 puffstage 1-2    11 larva L3 puffstage 3-6    18 larva L3 puffstage 7-9  26 white prepupae new  (29) white prepupae 12hr  (32) white prepupae 24hr  (37) pupae 2d postWPP  (34) pupae 3d postWPP    21 pupae 4d postWPP    13 adult male 01day    16 adult male 05day    20 adult male 30day    18 adult female 01day    12 adult female 05day    20 adult female 30day    19 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    33 embryo 02-04hr    38 embryo 04-06hr    33 embryo 06-08hr    36 embryo 08-10hr    36 embryo 10-12hr    30 embryo 12-14hr    29 embryo 14-16hr    20 embryo 16-18hr    21 embryo 18-20hr    17 embryo 20-22hr    19 embryo 22-24hr    21 larva L1    10 larva L2    9 larva L3 12hr old    7 larva L3 puffstage 1-2    11 larva L3 puffstage 3-6    18 larva L3 puffstage 7-9    26 white prepupae new    29 white prepupae 12hr    32 white prepupae 24hr    37 pupae 2d postWPP    34 pupae 3d postWPP    21 pupae 4d postWPP    13 adult male 01day    16 adult male 05day    20 adult male 30day    18 adult female 01day    12 adult female 05day    20 adult female 30day    19 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    33 embryo 02-04hr    38 embryo 04-06hr    33 embryo 06-08hr    36 embryo 08-10hr    36 embryo 10-12hr    30 embryo 12-14hr    29 embryo 14-16hr    20 embryo 16-18hr    21 embryo 18-20hr    17 embryo 20-22hr    19 embryo 22-24hr    21 larva L1    10 larva L2    9 larva L3 12hr old    7 larva L3 puffstage 1-2    11 larva L3 puffstage 3-6    18 larva L3 puffstage 7-9    26 white prepupae new    29 white prepupae 12hr    32 white prepupae 24hr    37 pupae 2d postWPP    34 pupae 3d postWPP    21 pupae 4d postWPP    13 adult male 01day    16 adult male 05day    20 adult male 30day    18 adult female 01day    12 adult female 05day    20 adult female 30day    19 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    33 embryo 02-04hr    38 embryo 04-06hr    33 embryo 06-08hr    36 embryo 08-10hr    36 embryo 10-12hr    30 embryo 12-14hr    29 embryo 14-16hr    20 embryo 16-18hr    21 embryo 18-20hr    17 embryo 20-22hr    19 embryo 22-24hr    21 larva L1    10 larva L2    9 larva L3 12hr old    7 larva L3 puffstage 1-2    11 larva L3 puffstage 3-6    18 larva L3 puffstage 7-9    26 white prepupae new    29 white prepupae 12hr    32 white prepupae 24hr    37 pupae 2d postWPP    34 pupae 3d postWPP    21 pupae 4d postWPP    13 adult male 01day    16 adult male 05day    20 adult male 30day    18 adult female 01day    12 adult female 05day    20 adult female 30day    19 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (33) embryo 02-04hr  (38) embryo 04-06hr  (33) embryo 06-08hr  (36) embryo 08-10hr  (36) embryo 10-12hr  30 embryo 12-14hr  29 embryo 14-16hr    20 embryo 16-18hr    21 embryo 18-20hr    17 embryo 20-22hr    19 embryo 22-24hr    21 larva L1    10 larva L2    9 larva L3 12hr old    7 larva L3 puffstage 1-2    11 larva L3 puffstage 3-6    18 larva L3 puffstage 7-9  26 white prepupae new  29 white prepupae 12hr  32 white prepupae 24hr  (37) pupae 2d postWPP  (34) pupae 3d postWPP    21 pupae 4d postWPP    13 adult male 01day    16 adult male 05day    20 adult male 30day    18 adult female 01day    12 adult female 05day    20 adult female 30day    19 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    33 embryo 02-04hr    38 embryo 04-06hr    33 embryo 06-08hr    36 embryo 08-10hr    36 embryo 10-12hr    30 embryo 12-14hr    29 embryo 14-16hr    20 embryo 16-18hr    21 embryo 18-20hr    17 embryo 20-22hr    19 embryo 22-24hr    21 larva L1    10 larva L2    9 larva L3 12hr old    7 larva L3 puffstage 1-2    11 larva L3 puffstage 3-6    18 larva L3 puffstage 7-9    26 white prepupae new    29 white prepupae 12hr    32 white prepupae 24hr    37 pupae 2d postWPP    34 pupae 3d postWPP    21 pupae 4d postWPP    13 adult male 01day    16 adult male 05day    20 adult male 30day    18 adult female 01day    12 adult female 05day    20 adult female 30day    19 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    33 embryo 02-04hr    38 embryo 04-06hr    33 embryo 06-08hr    36 embryo 08-10hr    36 embryo 10-12hr    30 embryo 12-14hr    29 embryo 14-16hr    20 embryo 16-18hr    21 embryo 18-20hr    17 embryo 20-22hr    19 embryo 22-24hr    21 larva L1    10 larva L2    9 larva L3 12hr old    7 larva L3 puffstage 1-2    11 larva L3 puffstage 3-6    18 larva L3 puffstage 7-9    26 white prepupae new    29 white prepupae 12hr    32 white prepupae 24hr    37 pupae 2d postWPP    34 pupae 3d postWPP    21 pupae 4d postWPP    13 adult male 01day    16 adult male 05day    20 adult male 30day    18 adult female 01day    12 adult female 05day    20 adult female 30day    19 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    20 Schneider line 2 Sg4    22 embryonic 1182-4H    28 embryonic GM2    35 embryonic Kc167    27 embryonic S1    43 embryonic S3    26 leg disc CME L1    24 wing disc CME-W2    21 wing disc ML-DmD8    24 wing disc ML-DmD9    39 wing disc ML-DmD16-c3    32 wing disc ML-DmD21    19 wing disc ML-DmD32    23 haltere disc ML-DmD17-c3    49 eye-antennal disc ML-DmD11    27 antennal disc ML-DmD20-c5    21 mixed discs ML-DmD4-c1    29 CNS ML-DmBG1-c1    33 CNS ML-DmBG2-c2    23 tumorous blood cells mbn2    17 ovary fGS/OSS    50 ovary OSC    50 ovary OSS    31 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    20 Schneider line 2 Sg4    22 embryonic 1182-4H  (28) embryonic GM2  (35) embryonic Kc167  (27) embryonic S1  (43) embryonic S3  26 leg disc CME L1    24 wing disc CME-W2    21 wing disc ML-DmD8    24 wing disc ML-DmD9  (39) wing disc ML-DmD16-c3  (32) wing disc ML-DmD21    19 wing disc ML-DmD32    23 haltere disc ML-DmD17-c3  (49) eye-antennal disc ML-DmD11  (27) antennal disc ML-DmD20-c5    21 mixed discs ML-DmD4-c1  (29) CNS ML-DmBG1-c1  (33) CNS ML-DmBG2-c2    23 tumorous blood cells mbn2    17 ovary fGS/OSS  (50) ovary OSC  (50) ovary OSS  (31) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    20 Schneider line 2 Sg4    22 embryonic 1182-4H    28 embryonic GM2    35 embryonic Kc167    27 embryonic S1    43 embryonic S3    26 leg disc CME L1    24 wing disc CME-W2    21 wing disc ML-DmD8    24 wing disc ML-DmD9    39 wing disc ML-DmD16-c3    32 wing disc ML-DmD21    19 wing disc ML-DmD32    23 haltere disc ML-DmD17-c3    49 eye-antennal disc ML-DmD11    27 antennal disc ML-DmD20-c5    21 mixed discs ML-DmD4-c1    29 CNS ML-DmBG1-c1    33 CNS ML-DmBG2-c2    23 tumorous blood cells mbn2    17 ovary fGS/OSS    50 ovary OSC    50 ovary OSS    31 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    20 Schneider line 2 Sg4    22 embryonic 1182-4H    28 embryonic GM2    35 embryonic Kc167    27 embryonic S1    43 embryonic S3    26 leg disc CME L1    24 wing disc CME-W2    21 wing disc ML-DmD8    24 wing disc ML-DmD9    39 wing disc ML-DmD16-c3    32 wing disc ML-DmD21    19 wing disc ML-DmD32    23 haltere disc ML-DmD17-c3    49 eye-antennal disc ML-DmD11    27 antennal disc ML-DmD20-c5    21 mixed discs ML-DmD4-c1    29 CNS ML-DmBG1-c1    33 CNS ML-DmBG2-c2    23 tumorous blood cells mbn2    17 ovary fGS/OSS    50 ovary OSC    50 ovary OSS    31 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    20 Schneider line 2 Sg4    22 embryonic 1182-4H    28 embryonic GM2    35 embryonic Kc167    27 embryonic S1    43 embryonic S3    26 leg disc CME L1    24 wing disc CME-W2    21 wing disc ML-DmD8    24 wing disc ML-DmD9    39 wing disc ML-DmD16-c3    32 wing disc ML-DmD21    19 wing disc ML-DmD32    23 haltere disc ML-DmD17-c3    49 eye-antennal disc ML-DmD11    27 antennal disc ML-DmD20-c5    21 mixed discs ML-DmD4-c1    29 CNS ML-DmBG1-c1    33 CNS ML-DmBG2-c2    23 tumorous blood cells mbn2    17 ovary fGS/OSS    50 ovary OSC    50 ovary OSS    31 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    20 Schneider line 2 Sg4    22 embryonic 1182-4H  28 embryonic GM2  (35) embryonic Kc167  27 embryonic S1  (43) embryonic S3  26 leg disc CME L1    24 wing disc CME-W2    21 wing disc ML-DmD8    24 wing disc ML-DmD9  (39) wing disc ML-DmD16-c3  32 wing disc ML-DmD21    19 wing disc ML-DmD32    23 haltere disc ML-DmD17-c3  (49) eye-antennal disc ML-DmD11  27 antennal disc ML-DmD20-c5    21 mixed discs ML-DmD4-c1  29 CNS ML-DmBG1-c1  (33) CNS ML-DmBG2-c2    23 tumorous blood cells mbn2    17 ovary fGS/OSS  (50) ovary OSC  (50) ovary OSS  31 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    20 Schneider line 2 Sg4    22 embryonic 1182-4H    28 embryonic GM2    35 embryonic Kc167    27 embryonic S1    43 embryonic S3    26 leg disc CME L1    24 wing disc CME-W2    21 wing disc ML-DmD8    24 wing disc ML-DmD9    39 wing disc ML-DmD16-c3    32 wing disc ML-DmD21    19 wing disc ML-DmD32    23 haltere disc ML-DmD17-c3    49 eye-antennal disc ML-DmD11    27 antennal disc ML-DmD20-c5    21 mixed discs ML-DmD4-c1    29 CNS ML-DmBG1-c1    33 CNS ML-DmBG2-c2    23 tumorous blood cells mbn2    17 ovary fGS/OSS    50 ovary OSC    50 ovary OSS    31 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    20 Schneider line 2 Sg4    22 embryonic 1182-4H    28 embryonic GM2    35 embryonic Kc167    27 embryonic S1    43 embryonic S3    26 leg disc CME L1    24 wing disc CME-W2    21 wing disc ML-DmD8    24 wing disc ML-DmD9    39 wing disc ML-DmD16-c3    32 wing disc ML-DmD21    19 wing disc ML-DmD32    23 haltere disc ML-DmD17-c3    49 eye-antennal disc ML-DmD11    27 antennal disc ML-DmD20-c5    21 mixed discs ML-DmD4-c1    29 CNS ML-DmBG1-c1    33 CNS ML-DmBG2-c2    23 tumorous blood cells mbn2    17 ovary fGS/OSS    50 ovary OSC    50 ovary OSS    31 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    18 cold shock, 4-day adult    14 heat shock, 4-day adult    15 Cadmium 50 mM 6 hrs, larvae L3    8 Cadmium 50 mM 12 hrs, larvae L3    16 Cadmium 50 mM 48 hrs, 4-day adult    20 Cadmium 100 mM 48 hrs, 4-day adult    38 Copper 0.5 mM 12 hrs, larvae L3    9 Copper 15 mM 48 hrs, 4-day adult    28 Zinc 5 mM 12 hrs, larvae L3    12 Zinc 4.5 mM 48 hrs, 4-day adult    22 Ethanol 2.5% 3 hrs, larvae L3    24 Ethanol 5% 3 hrs, larvae L3    11 Ethanol 10% 3 hrs, larvae L3    9 Caffeine 1.5 mg/ml 4 hrs, larvae L3    13 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    29 Caffeine 25 mg/ml 48 hrs, 4-day adult    16 Paraquat 5 mM 48 hrs, 4-day adult    26 Paraquat 10 mM 48 hrs, 4-day adult    21 Rotenone 2 μg 12 hrs, larvae L3    12 Rotenone 8 μg 12 hrs, larvae L3    7 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    18 cold shock, 4-day adult    14 heat shock, 4-day adult    15 Cadmium 50 mM 6 hrs, larvae L3    8 Cadmium 50 mM 12 hrs, larvae L3    16 Cadmium 50 mM 48 hrs, 4-day adult    20 Cadmium 100 mM 48 hrs, 4-day adult  (38) Copper 0.5 mM 12 hrs, larvae L3    9 Copper 15 mM 48 hrs, 4-day adult  (28) Zinc 5 mM 12 hrs, larvae L3    12 Zinc 4.5 mM 48 hrs, 4-day adult    22 Ethanol 2.5% 3 hrs, larvae L3    24 Ethanol 5% 3 hrs, larvae L3    11 Ethanol 10% 3 hrs, larvae L3    9 Caffeine 1.5 mg/ml 4 hrs, larvae L3    13 Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (29) Caffeine 25 mg/ml 48 hrs, 4-day adult    16 Paraquat 5 mM 48 hrs, 4-day adult  26 Paraquat 10 mM 48 hrs, 4-day adult    21 Rotenone 2 μg 12 hrs, larvae L3    12 Rotenone 8 μg 12 hrs, larvae L3    7 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    18 cold shock, 4-day adult    14 heat shock, 4-day adult    15 Cadmium 50 mM 6 hrs, larvae L3    8 Cadmium 50 mM 12 hrs, larvae L3    16 Cadmium 50 mM 48 hrs, 4-day adult    20 Cadmium 100 mM 48 hrs, 4-day adult    38 Copper 0.5 mM 12 hrs, larvae L3    9 Copper 15 mM 48 hrs, 4-day adult    28 Zinc 5 mM 12 hrs, larvae L3    12 Zinc 4.5 mM 48 hrs, 4-day adult    22 Ethanol 2.5% 3 hrs, larvae L3    24 Ethanol 5% 3 hrs, larvae L3    11 Ethanol 10% 3 hrs, larvae L3    9 Caffeine 1.5 mg/ml 4 hrs, larvae L3    13 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    29 Caffeine 25 mg/ml 48 hrs, 4-day adult    16 Paraquat 5 mM 48 hrs, 4-day adult    26 Paraquat 10 mM 48 hrs, 4-day adult    21 Rotenone 2 μg 12 hrs, larvae L3    12 Rotenone 8 μg 12 hrs, larvae L3    7 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    18 cold shock, 4-day adult    14 heat shock, 4-day adult    15 Cadmium 50 mM 6 hrs, larvae L3    8 Cadmium 50 mM 12 hrs, larvae L3    16 Cadmium 50 mM 48 hrs, 4-day adult    20 Cadmium 100 mM 48 hrs, 4-day adult    38 Copper 0.5 mM 12 hrs, larvae L3    9 Copper 15 mM 48 hrs, 4-day adult    28 Zinc 5 mM 12 hrs, larvae L3    12 Zinc 4.5 mM 48 hrs, 4-day adult    22 Ethanol 2.5% 3 hrs, larvae L3    24 Ethanol 5% 3 hrs, larvae L3    11 Ethanol 10% 3 hrs, larvae L3    9 Caffeine 1.5 mg/ml 4 hrs, larvae L3    13 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    29 Caffeine 25 mg/ml 48 hrs, 4-day adult    16 Paraquat 5 mM 48 hrs, 4-day adult    26 Paraquat 10 mM 48 hrs, 4-day adult    21 Rotenone 2 μg 12 hrs, larvae L3    12 Rotenone 8 μg 12 hrs, larvae L3    7 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    18 cold shock, 4-day adult    14 heat shock, 4-day adult    15 Cadmium 50 mM 6 hrs, larvae L3    8 Cadmium 50 mM 12 hrs, larvae L3    16 Cadmium 50 mM 48 hrs, 4-day adult    20 Cadmium 100 mM 48 hrs, 4-day adult    38 Copper 0.5 mM 12 hrs, larvae L3    9 Copper 15 mM 48 hrs, 4-day adult    28 Zinc 5 mM 12 hrs, larvae L3    12 Zinc 4.5 mM 48 hrs, 4-day adult    22 Ethanol 2.5% 3 hrs, larvae L3    24 Ethanol 5% 3 hrs, larvae L3    11 Ethanol 10% 3 hrs, larvae L3    9 Caffeine 1.5 mg/ml 4 hrs, larvae L3    13 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    29 Caffeine 25 mg/ml 48 hrs, 4-day adult    16 Paraquat 5 mM 48 hrs, 4-day adult    26 Paraquat 10 mM 48 hrs, 4-day adult    21 Rotenone 2 μg 12 hrs, larvae L3    12 Rotenone 8 μg 12 hrs, larvae L3    7 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    18 cold shock, 4-day adult    14 heat shock, 4-day adult    15 Cadmium 50 mM 6 hrs, larvae L3    8 Cadmium 50 mM 12 hrs, larvae L3    16 Cadmium 50 mM 48 hrs, 4-day adult    20 Cadmium 100 mM 48 hrs, 4-day adult  (38) Copper 0.5 mM 12 hrs, larvae L3    9 Copper 15 mM 48 hrs, 4-day adult  28 Zinc 5 mM 12 hrs, larvae L3    12 Zinc 4.5 mM 48 hrs, 4-day adult    22 Ethanol 2.5% 3 hrs, larvae L3    24 Ethanol 5% 3 hrs, larvae L3    11 Ethanol 10% 3 hrs, larvae L3    9 Caffeine 1.5 mg/ml 4 hrs, larvae L3    13 Caffeine 2.5 mg/ml 48 hrs, 4-day adult  29 Caffeine 25 mg/ml 48 hrs, 4-day adult    16 Paraquat 5 mM 48 hrs, 4-day adult  26 Paraquat 10 mM 48 hrs, 4-day adult    21 Rotenone 2 μg 12 hrs, larvae L3    12 Rotenone 8 μg 12 hrs, larvae L3    7 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    18 cold shock, 4-day adult    14 heat shock, 4-day adult    15 Cadmium 50 mM 6 hrs, larvae L3    8 Cadmium 50 mM 12 hrs, larvae L3    16 Cadmium 50 mM 48 hrs, 4-day adult    20 Cadmium 100 mM 48 hrs, 4-day adult    38 Copper 0.5 mM 12 hrs, larvae L3    9 Copper 15 mM 48 hrs, 4-day adult    28 Zinc 5 mM 12 hrs, larvae L3    12 Zinc 4.5 mM 48 hrs, 4-day adult    22 Ethanol 2.5% 3 hrs, larvae L3    24 Ethanol 5% 3 hrs, larvae L3    11 Ethanol 10% 3 hrs, larvae L3    9 Caffeine 1.5 mg/ml 4 hrs, larvae L3    13 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    29 Caffeine 25 mg/ml 48 hrs, 4-day adult    16 Paraquat 5 mM 48 hrs, 4-day adult    26 Paraquat 10 mM 48 hrs, 4-day adult    21 Rotenone 2 μg 12 hrs, larvae L3    12 Rotenone 8 μg 12 hrs, larvae L3    7 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    18 cold shock, 4-day adult    14 heat shock, 4-day adult    15 Cadmium 50 mM 6 hrs, larvae L3    8 Cadmium 50 mM 12 hrs, larvae L3    16 Cadmium 50 mM 48 hrs, 4-day adult    20 Cadmium 100 mM 48 hrs, 4-day adult    38 Copper 0.5 mM 12 hrs, larvae L3    9 Copper 15 mM 48 hrs, 4-day adult    28 Zinc 5 mM 12 hrs, larvae L3    12 Zinc 4.5 mM 48 hrs, 4-day adult    22 Ethanol 2.5% 3 hrs, larvae L3    24 Ethanol 5% 3 hrs, larvae L3    11 Ethanol 10% 3 hrs, larvae L3    9 Caffeine 1.5 mg/ml 4 hrs, larvae L3    13 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    29 Caffeine 25 mg/ml 48 hrs, 4-day adult    16 Paraquat 5 mM 48 hrs, 4-day adult    26 Paraquat 10 mM 48 hrs, 4-day adult    21 Rotenone 2 μg 12 hrs, larvae L3    12 Rotenone 8 μg 12 hrs, larvae L3    7 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_30 mE1_20_mRNA_expression_cluster_03
External Data & Images
Linkouts	BDGP expression data • LD07457 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0036305 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG10984-RC FlyExpress - Embryonic expression images (BDGP data) • Show all FlyExpress processed images for CG10984 Stages(s) 1-3 Stages(s) 4-6 Stages(s) 11-12 Stages(s) 13-16
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele partially lethal - majority die | pupal stage, with Scer\GAL4pnr-MD237 CG10984GD5129 viable CG10984f05402 Sterility Allele fertile CG10984f05402 Phenotype manifest in Allele
Classical Alleles ( 4 )
For All Classical Alleles Show
Allele of CG10984 Class Mutagen Stocks Known lesion CG10984f05402 piggyBac transposase 2 -- CG10984c06514 piggyBac transposase 1 -- CG10984MI01719 1 -- CG10984CPTI002035 piggyBac transposase 0 Yes
Alleles Carried on Transgenic Constructs ( 3 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG10984 Class Mutagen Stocks Known lesion CG10984GD5129 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes CG10984KK100152 in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes CG10984NIG.10984R in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(3L)Exel6117 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD5129} NA P{KK100152} NA P{NIG.10984R} NA
Insertions
	Type of insertions Name Expression data miscellaneous insertions Mi{MIC}CG10973MI01719 NA PBac{681.P.FSVS-1}CG10984CPTI002035 NA PBac{PB}CG10984c06514 NA PBac{WH}CG10984f05402 NA
Gene Ontology: Function, Process & Cellular Component ( 0 unique terms )
	There is no information supporting a biological process, cellular component or molecular function term for this gene. (Based on a review of available data on: 2012-06-11)
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 0 terms )
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
protein-protein
Interacting group Assay References
CG10984 - Hsp23 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG10984 - Hsp27 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG10984 - Hsp68 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG10984 - Hsp70Aa anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG10984 - Hsp70Ba anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG10984 - Klp61F anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG10984 - Ote anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG10984 - Rab5 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23)
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG10984 allele Gene References
External Data
Linkouts	DPiM - DPiM, Drosophila Protein interaction Map • FBgn0036305 DroID - A comprehensive database of gene and protein interactions. • FBgn0036305
Orthologs
OrthoDB Orthologs (53) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG69CQT9 Dipteran inclusive ortholog search EOG634WFC Insect inclusive ortholog search EOG63JB1Q Arthropod inclusive ortholog search EOG6GHX52 Metazoa inclusive ortholog search EOG6ND06Z
Orthologs in Drosophila Species (EOG69CQT9)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\CG10984     Drosophila simulans   Dsim\GD14401 Y   Drosophila sechellia   Dsec\GM25369 Y   Drosophila erecta   Dere\GG15594 Y   Drosophila yakuba   Dyak\GE21921 Y   Drosophila ananassae   Dana\GF23568 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA10687 Y   Drosophila persimilis   Dper\GL25208 Y   Drosophila willistoni   Dwil\GK18826 Y   Drosophila virilis   Dvir\GJ11499 Y   Drosophila mojavensis   Dmoj\GI12269 Y   Drosophila grimshawi   Dgri\GH14722 Y
Orthologs in non-Drosophila Dipterans (EOG634WFC)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL014962   Anopheles gambiae Malaria mosquito  Agam\AGAP005649   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ015901   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ020237
Orthologs in non-Dipteran Insects (EOG63JB1Q)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\GB40765   Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG004672   Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG026495   Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH13886   Atta cephalotes Leafcutter ant  Acep\ACEP22664   Atta cephalotes Leafcutter ant  Acep\ACEP22667   Camponotus floridanus Florida carpenter ant  Cflo\CFLO12652   Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL16146   Linepithema humile Argentine ant  Lhum\LH12698   Pogonomyrmex barbatus Red harvester ant  Pbar\PB15506   Solenopsis invicta Red fire ant  Sinv\SINV19676   Acyrthosiphon pisum Pea aphid  Apim\ACYPI004934   Acyrthosiphon pisum Pea aphid  Apim\ACYPI001412   Acyrthosiphon pisum Pea aphid  Apim\ACYPI004076   Acyrthosiphon pisum Pea aphid  Apim\ACYPI007062   Bombyx mori Silkmoth  Bmor\BGIBMGA000503   Pediculus humanus Human body louse  Phum\PHUM580430   Tribolium castaneum Red flour beetle  Tcas\TC002375
Orthologs in non-Insect Arthropods (EOG6GHX52)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\Rcl1   Ixodes scapularis Deer tick  Isca\ISCW014864
Orthologs in non-Arthropod Metazoa (EOG6ND06Z)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_026356gn   Danio rerio Zebrafish  Drer\ankrd12   Danio rerio Zebrafish  Drer\ENSDARG00000051886   Xenopus tropicalis Western clawed frog  Xtro\ENSXETG00000011277   Xenopus tropicalis Western clawed frog  Xtro\ankrd12   Gallus gallus Domestic chicken  Ggal\ANKRD11   Gallus gallus Domestic chicken  Ggal\ENSGALG00000001216   Gallus gallus Domestic chicken  Ggal\ENSGALG00000014506   Gallus gallus Domestic chicken  Ggal\LOC425899   Gallus gallus Domestic chicken  Ggal\ENSGALG00000018390   Gallus gallus Domestic chicken  Ggal\ENSGALG00000022161   Mus musculus House mouse  Mmus\Ankrd11   Mus musculus House mouse  Mmus\Ankrd12   Rattus norvegicus Norway rat  Rnor\Ankrd12   Rattus norvegicus Norway rat  Rnor\ENSRNOG00000027906   Homo sapiens Human  Hsap\ANKRD11   Homo sapiens Human  Hsap\ANKRD12
Human Orthologs (2)
Gene OMIM HGNC Hsap\ANKRD11     Hsap\ANKRD12
AAA Orthologs (11) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD14401 Drosophila sechellia Dsec\GM25369 Drosophila erecta Dere\GG15594 Drosophila yakuba Dyak\GE21921 Drosophila ananassae Dana\GF23568 Drosophila pseudoobscura pseudoobscura Dpse\GA10687 Drosophila persimilis Dper\GL25208 Drosophila willistoni Dwil\GK18826 Drosophila virilis Dvir\GJ11499 Drosophila mojavensis Dmoj\GI12269 Drosophila grimshawi Dgri\GH14722
Stocks & Reagents
Stocks Listed in FlyBase ( 6 )
Bloomington	18859 w1118; PBac{WH}CG10984f05402 34240 y1 w*; Mi{MIC}CG10973MI01719 CG10984MI01719
Harvard	- PBac{PB}CG10984c06514 - PBac{WH}CG10984f05402
VDRC	v15625 w1118 P{GD5129}v15625 v15627 w1118; P{GD5129}v15627/TM3
Genomic Clones ( 1 )
	BACR20I01 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 37 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	LD07457 RE08495
Other clones	DPiM_LD07457
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT08589 AT27282 LD19548 RE08453 RE20101 RE21204 RE21848 RE57387 RE61809 RE64036 RE65235 SD16312 SD21222
Other clones	42729 58561 183883 214253.45 bs33e04 Dmel_dig_005457_0612_1456 EK157735 EK181224 EP02112 ESG0111d.B21.1_F04 RP004062667 RP004104739 RP004177290 RP004209906 RP004215154 RP004217244 RP004245865 RP004249115 RP004307458 RP004444091 RP004542991
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0036305 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 39446
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_140336 NM_168510 NM_168511 NM_001274853 RefSeq (Proteins) • NP_648593 NP_729823 NP_729824 NP_001261782 DDBJ / EMBL / GenBank • AA264023 AAF49889 AAL39513 AAN11854 AAN11855 AGB94475 AW941641 AY069368 BE662244 CZ470756 CZ487966 Entrez Gene - A searchable database of RefSeq genes. • 39446 UniProtKB/TrEMBL • Q8IQI3 Q8T0E7
Other Crossreferences
	BDGP expression data - Patterns of gene expression in Drosophila embryogenesis • LD07457
Linkouts
	DPiM - DPiM, Drosophila Protein interaction Map • FBgn0036305 DroID - A comprehensive database of gene and protein interactions. • FBgn0036305 DRSC - Results from RNAi screens. • FBgn0036305 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0036305 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG10984-RC FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0036305 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 39446 modMine - Data generated by the modENCODE project. • FBgn0036305
Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	CG10984 (Rees et al., 2011, Keleman et al., 2009.8.5, Japanese National Institute of Genetics, 2012.5.21)
Name Synonym
Secondary FlyBase IDs
References ( 24 )
Generate a list of	All references relating to this gene ( 24 )
List References by type	Research paper  ( 2 ) Supplementary material  ( 3 ) Personal communication to FlyBase  ( 12 ) FlyBase analysis  ( 3 ) Stock list  ( 1 ) Website  ( 1 ) Curated genome annotation  ( 1 )
Recent research papers ( 1 )
	Rees et al., 2011, Mol. Cell. Proteomics 10(6): M110.002386 In Vivo Analysis of Proteomes and Interactomes Using Parallel Affinity Capture (iPAC) Coupled to Mass Spectrometry. [FBrf0213845] Show all research papers ...