Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 5.45
There is only one protein coding transcript and one polypeptide associated with this gene
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Srrm1 using the Feature Mapper tool.
Srrm1 transcripts are ubiquitous and at high levels in 0-1 hr embryos and then accumulate around the embryonic periphery at 2-3 hr. At 4-5 pattern they are observed in a segmental pattern. At 7-8 hr, they accumulate in the ventral nerve cord and brain. Later they are primarily restricted to the developing CNS with some expression in the midgut. By 16 hr, Srrm1 is detected exclusively in the condensed CNS.
Srrm1 protein staining is ubiquitous in early embryos and is observed in a puctate pattern in nuclei. Staining remains punctate and nuclear until cellularization. At ~11 hr of development, low levels of protein are seen widely distributed around the embryo with higher concentrations in the midgut, anus, and regions of hemocyte development in the head area. Fairly uniform distribution of Srrm1 protein is observed in imaginal discs, except in the eye disc, where higher levels are observed in differentiating photoreceptor precursors.
GBrowse - Visual display of RNA-Seq signalsView Dmel\Srrm1 in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for identity of: Srrm1 SRm160
Renamed from 'SRm160' to 'Srrm1' because (i) the original symbol was based on that of the human ortholog according to its size in kDa, but the size in flies is different; and (ii) the human ortholog has been renamed to SRRM1.