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Gene Dmel\SRm160

General Information
Symbol	Dmel\SRm160	Species	D. melanogaster
Name	SRm160	Annotation symbol	CG11274
Feature type	protein_coding_gene	FlyBase ID	FBgn0036340
Gene Model Status	Current	Stock availability	4 publicly available
Genomic Location
Chromosome (arm)	3L	Recombination map
Cytogenetic map	69F6-69F6	Sequence location	3L:13,029,921..13,034,076 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene SRm160 is referred to in FlyBase by the symbol Dmel\SRm160 (CG11274, FBgn0036340). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. It is reported to be involved in the biological process: mRNA splicing, via spliceosome. 6 alleles are reported. The phenotypes of these alleles are annotated with: trichogen cell; mesothoracic tergum. It has one annotated transcript and one annotated polypeptide. Protein features are: PWI domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-12 hour embryonic stages. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: larval central nervous system. Comments on Affy2 ProbeSet: ProbeSet 1632470_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of SRm160. Gene sequence location is 3L:13029921..13034076.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 69F6-69F6   Limits computationally determined from genome sequence between P{lacW}RpS12s2783 and P{PZ}l(3)0422004220&P{lacW}l(3)j10B6j10B6
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\SRm160 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.45 Low-frequency RNA-seq exon junction(s) not annotated.
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) SRm160-RA FBtr0075883  NM_140370   3862   954
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein SRm160-PA   FBpp0075617   107.6   954   12.13     NP_648627   AAF49848
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • PWI domain (IPR002483)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA440655   AA539347   AA567455   AA816691   AA941745   AA949233   AA979005   AE014296 AAF49848   AI402940   AI456753   AI457033   AI512526   AI513640   AI513912   AI514593   AI514788   AI514789   AI515567   AI518269   AI519274   AI542749   BG637646   BG638828   BG639055   BI169544   BI170887   BI173328   BI173826   BI214222   BI216238   BI239006   BI242953   BI355081   BI356771   BI357321   BI357768   BI358152   BI358153   BI363162   BI364848   BI370797   BI371801   BI372601   BI372877   BI482556   BI485786   BI486332   BI486361   BI486565   BI575876   BI577496   BI577943   BI578024   BP543756   BT015197 AAT94426   BT099646   CO266631   CO269077   CO276534   CO277182   CO277286   CO304942   CO329582   CO340426   CO343064   EC052364   EC065132   EC065764   EC067347   EC197682   EC197755   EC197773   EC221974   EC243103   EC252373   EC254627   EV586240   EV589419   GH943638   GH961218   GH976193   GH978093   GH978263
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9VU43 Q6AWQ1
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
northern blot Stage Tissue/Position (including subcellular localization) Reference     (Gatfield and Izaurralde, 2002) Comment:expression assayed in cultured cells
Additional Descriptive Data
	SRm160 transcripts are expressed in S2 cells. (Gatfield and Izaurralde, 2002)
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
western blot Stage Tissue/Position (including subcellular localization) Reference     (Gatfield and Izaurralde, 2002) Comment:expression assayed in cultured cells
Additional Descriptive Data
	SRm160 protein isdetected in S2 cells. (Gatfield and Izaurralde, 2002)
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
catalytic step 2 spliceosome inferred from direct assay (Herold et al., 2009) precatalytic spliceosome inferred from direct assay (Herold et al., 2009)
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: larval central nervous system. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    109.95 Larval Midgut    1.3 Larval Hindgut    22.2 Larval Malpighian Tubules    22.3 Larval Fat Body    21.2 Larval Salivary Gland    15.3 Larval Trachea    43.5 Larval Carcass    25.05 Adult Head    27.3 Adult Eye    38.975 Adult Brain    76 Adult Thoracic-Abdominal Ganglion    66.4 Adult Crop    17.7 Adult Midgut    6.7 Adult Hindgut    17 Adult Malpighian Tubules    14.3 Adult Fat Body    10 Adult Salivary Gland    19.4 Adult Heart    17 Adult VirginFemale Spermatheca    11.3 Adult InseminatedFemale Spermatheca    9.6 Adult Ovary    81.3 Adult Testis    23.7 Adult Male Accessory Gland    33.2 Adult Carcass    19.6 Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    109.95 Larval Midgut    1.3 Larval Hindgut    22.2 Larval Malpighian Tubules    22.3 Larval Fat Body    21.2 Larval Salivary Gland    15.3 Larval Trachea    43.5 Larval Carcass    25.05 Adult Head    27.3 Adult Eye    38.975 Adult Brain    76 Adult Thoracic-Abdominal Ganglion    66.4 Adult Crop    17.7 Adult Midgut    6.7 Adult Hindgut    17 Adult Malpighian Tubules    14.3 Adult Fat Body    10 Adult Salivary Gland    19.4 Adult Heart    17 Adult VirginFemale Spermatheca    11.3 Adult InseminatedFemale Spermatheca    9.6 Adult Ovary    81.3 Adult Testis    23.7 Adult Male Accessory Gland    33.2 Adult Carcass    19.6 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    109.95 Larval Midgut    1.3 Larval Hindgut    22.2 Larval Malpighian Tubules    22.3 Larval Fat Body    21.2 Larval Salivary Gland    15.3 Larval Trachea    43.5 Larval Carcass    25.05 Adult Head    27.3 Adult Eye    38.975 Adult Brain    76 Adult Thoracic-Abdominal Ganglion    66.4 Adult Crop    17.7 Adult Midgut    6.7 Adult Hindgut    17 Adult Malpighian Tubules    14.3 Adult Fat Body    10 Adult Salivary Gland    19.4 Adult Heart    17 Adult VirginFemale Spermatheca    11.3 Adult InseminatedFemale Spermatheca    9.6 Adult Ovary    81.3 Adult Testis    23.7 Adult Male Accessory Gland    33.2 Adult Carcass    19.6 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    109.95 Larval Midgut    1.3 Larval Hindgut    22.2 Larval Malpighian Tubules    22.3 Larval Fat Body    21.2 Larval Salivary Gland    15.3 Larval Trachea    43.5 Larval Carcass    25.05 Adult Head    27.3 Adult Eye    38.975 Adult Brain    76 Adult Thoracic-Abdominal Ganglion    66.4 Adult Crop    17.7 Adult Midgut    6.7 Adult Hindgut    17 Adult Malpighian Tubules    14.3 Adult Fat Body    10 Adult Salivary Gland    19.4 Adult Heart    17 Adult VirginFemale Spermatheca    11.3 Adult InseminatedFemale Spermatheca    9.6 Adult Ovary    81.3 Adult Testis    23.7 Adult Male Accessory Gland    33.2 Adult Carcass    19.6 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    109.95 Larval Midgut    1.3 Larval Hindgut    22.2 Larval Malpighian Tubules    22.3 Larval Fat Body    21.2 Larval Salivary Gland    15.3 Larval Trachea    43.5 Larval Carcass    25.05 Adult Head    27.3 Adult Eye    38.975 Adult Brain    76 Adult Thoracic-Abdominal Ganglion    66.4 Adult Crop    17.7 Adult Midgut    6.7 Adult Hindgut    17 Adult Malpighian Tubules    14.3 Adult Fat Body    10 Adult Salivary Gland    19.4 Adult Heart    17 Adult VirginFemale Spermatheca    11.3 Adult InseminatedFemale Spermatheca    9.6 Adult Ovary    81.3 Adult Testis    23.7 Adult Male Accessory Gland    33.2 Adult Carcass    19.6 Expression Level Scale  None   Low   Moderate  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    109.95 Larval Midgut    1.3 Larval Hindgut    22.2 Larval Malpighian Tubules    22.3 Larval Fat Body    21.2 Larval Salivary Gland    15.3 Larval Trachea    43.5 Larval Carcass    25.05 Adult Head    27.3 Adult Eye    38.975 Adult Brain    76 Adult Thoracic-Abdominal Ganglion    66.4 Adult Crop    17.7 Adult Midgut    6.7 Adult Hindgut    17 Adult Malpighian Tubules    14.3 Adult Fat Body    10 Adult Salivary Gland    19.4 Adult Heart    17 Adult VirginFemale Spermatheca    11.3 Adult InseminatedFemale Spermatheca    9.6 Adult Ovary    81.3 Adult Testis    23.7 Adult Male Accessory Gland    33.2 Adult Carcass    19.6 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    109.95 Larval Midgut    1.3 Larval Hindgut    22.2 Larval Malpighian Tubules    22.3 Larval Fat Body    21.2 Larval Salivary Gland    15.3 Larval Trachea    43.5 Larval Carcass    25.05 Adult Head    27.3 Adult Eye    38.975 Adult Brain    76 Adult Thoracic-Abdominal Ganglion    66.4 Adult Crop    17.7 Adult Midgut    6.7 Adult Hindgut    17 Adult Malpighian Tubules    14.3 Adult Fat Body    10 Adult Salivary Gland    19.4 Adult Heart    17 Adult VirginFemale Spermatheca    11.3 Adult InseminatedFemale Spermatheca    9.6 Adult Ovary    81.3 Adult Testis    23.7 Adult Male Accessory Gland    33.2 Adult Carcass    19.6 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    109.95 Larval Midgut    1.3 Larval Hindgut    22.2 Larval Malpighian Tubules    22.3 Larval Fat Body    21.2 Larval Salivary Gland    15.3 Larval Trachea    43.5 Larval Carcass    25.05 Adult Head    27.3 Adult Eye    38.975 Adult Brain    76 Adult Thoracic-Abdominal Ganglion    66.4 Adult Crop    17.7 Adult Midgut    6.7 Adult Hindgut    17 Adult Malpighian Tubules    14.3 Adult Fat Body    10 Adult Salivary Gland    19.4 Adult Heart    17 Adult VirginFemale Spermatheca    11.3 Adult InseminatedFemale Spermatheca    9.6 Adult Ovary    81.3 Adult Testis    23.7 Adult Male Accessory Gland    33.2 Adult Carcass    19.6 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    27.3   NA  Eye    38.975   NA  Brain    76   109.95  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    66.4   NA  Crop    17.7   1.3  Midgut    6.7   22.2  Hindgut    17   no informative data  Malpighian Tubules    no informative data   no informative data  Fat Body    no informative data   no informative data  Salivary Gland    no informative data   NA  Heart    17   43.5  Trachea    NA   NA  VirginFemale Spermatheca    no informative data   NA  InseminatedFemale Spermatheca    9.6   NA  Ovary    81.3   NA  Testis    23.7   NA  Male Accessory Gland    33.2   25.05  Carcass    19.6 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    32 central nervous system, larvae L3    58 central nervous system, pupae P8    32 head, virgin 1-day female    12 head, virgin 4-day female    12 head, virgin 20-day female    8 head, mated 1-day female    14 head, mated 4-day female    10 head, mated 20-day female    8 head, mated 1-day male    17 head, mated 4-day male    18 head, mated 20-day male    15 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    2 digestive system, larvae L3 wandering    5 digestive system, 1-day adult    5 digestive system, 4-day adult    9 digestive system, 20-day adult    7 fat body, larvae L3 wandering    6 fat body, white prepupae    11 fat body, pupae P8    13 carcass, larvae L3 wandering    28 carcass, 1-day adult    5 carcass, 4-day adult    8 carcass, 20-day adult    6 ovary, virgin 4-day female    49 ovary, mated 4-day female    59 testis, mated 4-day male    13 accessory gland, mated 4-day male    9 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (32) central nervous system, larvae L3  (58) central nervous system, pupae P8  (32) head, virgin 1-day female    12 head, virgin 4-day female    12 head, virgin 20-day female    8 head, mated 1-day female    14 head, mated 4-day female    10 head, mated 20-day female    8 head, mated 1-day male    17 head, mated 4-day male    18 head, mated 20-day male    15 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    2 digestive system, larvae L3 wandering    5 digestive system, 1-day adult    5 digestive system, 4-day adult    9 digestive system, 20-day adult    7 fat body, larvae L3 wandering    6 fat body, white prepupae    11 fat body, pupae P8    13 carcass, larvae L3 wandering  (28) carcass, 1-day adult    5 carcass, 4-day adult    8 carcass, 20-day adult    6 ovary, virgin 4-day female  (49) ovary, mated 4-day female  (59) testis, mated 4-day male    13 accessory gland, mated 4-day male    9 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    32 central nervous system, larvae L3    58 central nervous system, pupae P8    32 head, virgin 1-day female    12 head, virgin 4-day female    12 head, virgin 20-day female    8 head, mated 1-day female    14 head, mated 4-day female    10 head, mated 20-day female    8 head, mated 1-day male    17 head, mated 4-day male    18 head, mated 20-day male    15 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    2 digestive system, larvae L3 wandering    5 digestive system, 1-day adult    5 digestive system, 4-day adult    9 digestive system, 20-day adult    7 fat body, larvae L3 wandering    6 fat body, white prepupae    11 fat body, pupae P8    13 carcass, larvae L3 wandering    28 carcass, 1-day adult    5 carcass, 4-day adult    8 carcass, 20-day adult    6 ovary, virgin 4-day female    49 ovary, mated 4-day female    59 testis, mated 4-day male    13 accessory gland, mated 4-day male    9 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    32 central nervous system, larvae L3    58 central nervous system, pupae P8    32 head, virgin 1-day female    12 head, virgin 4-day female    12 head, virgin 20-day female    8 head, mated 1-day female    14 head, mated 4-day female    10 head, mated 20-day female    8 head, mated 1-day male    17 head, mated 4-day male    18 head, mated 20-day male    15 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    2 digestive system, larvae L3 wandering    5 digestive system, 1-day adult    5 digestive system, 4-day adult    9 digestive system, 20-day adult    7 fat body, larvae L3 wandering    6 fat body, white prepupae    11 fat body, pupae P8    13 carcass, larvae L3 wandering    28 carcass, 1-day adult    5 carcass, 4-day adult    8 carcass, 20-day adult    6 ovary, virgin 4-day female    49 ovary, mated 4-day female    59 testis, mated 4-day male    13 accessory gland, mated 4-day male    9 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    32 central nervous system, larvae L3    58 central nervous system, pupae P8    32 head, virgin 1-day female    12 head, virgin 4-day female    12 head, virgin 20-day female    8 head, mated 1-day female    14 head, mated 4-day female    10 head, mated 20-day female    8 head, mated 1-day male    17 head, mated 4-day male    18 head, mated 20-day male    15 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    2 digestive system, larvae L3 wandering    5 digestive system, 1-day adult    5 digestive system, 4-day adult    9 digestive system, 20-day adult    7 fat body, larvae L3 wandering    6 fat body, white prepupae    11 fat body, pupae P8    13 carcass, larvae L3 wandering    28 carcass, 1-day adult    5 carcass, 4-day adult    8 carcass, 20-day adult    6 ovary, virgin 4-day female    49 ovary, mated 4-day female    59 testis, mated 4-day male    13 accessory gland, mated 4-day male    9 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  32 central nervous system, larvae L3  (58) central nervous system, pupae P8  32 head, virgin 1-day female    12 head, virgin 4-day female    12 head, virgin 20-day female    8 head, mated 1-day female    14 head, mated 4-day female    10 head, mated 20-day female    8 head, mated 1-day male    17 head, mated 4-day male    18 head, mated 20-day male    15 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    2 digestive system, larvae L3 wandering    5 digestive system, 1-day adult    5 digestive system, 4-day adult    9 digestive system, 20-day adult    7 fat body, larvae L3 wandering    6 fat body, white prepupae    11 fat body, pupae P8    13 carcass, larvae L3 wandering  28 carcass, 1-day adult    5 carcass, 4-day adult    8 carcass, 20-day adult    6 ovary, virgin 4-day female  (49) ovary, mated 4-day female  (59) testis, mated 4-day male    13 accessory gland, mated 4-day male    9 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    32 central nervous system, larvae L3    58 central nervous system, pupae P8    32 head, virgin 1-day female    12 head, virgin 4-day female    12 head, virgin 20-day female    8 head, mated 1-day female    14 head, mated 4-day female    10 head, mated 20-day female    8 head, mated 1-day male    17 head, mated 4-day male    18 head, mated 20-day male    15 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    2 digestive system, larvae L3 wandering    5 digestive system, 1-day adult    5 digestive system, 4-day adult    9 digestive system, 20-day adult    7 fat body, larvae L3 wandering    6 fat body, white prepupae    11 fat body, pupae P8    13 carcass, larvae L3 wandering    28 carcass, 1-day adult    5 carcass, 4-day adult    8 carcass, 20-day adult    6 ovary, virgin 4-day female    49 ovary, mated 4-day female    59 testis, mated 4-day male    13 accessory gland, mated 4-day male    9 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    32 central nervous system, larvae L3    58 central nervous system, pupae P8    32 head, virgin 1-day female    12 head, virgin 4-day female    12 head, virgin 20-day female    8 head, mated 1-day female    14 head, mated 4-day female    10 head, mated 20-day female    8 head, mated 1-day male    17 head, mated 4-day male    18 head, mated 20-day male    15 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    2 digestive system, larvae L3 wandering    5 digestive system, 1-day adult    5 digestive system, 4-day adult    9 digestive system, 20-day adult    7 fat body, larvae L3 wandering    6 fat body, white prepupae    11 fat body, pupae P8    13 carcass, larvae L3 wandering    28 carcass, 1-day adult    5 carcass, 4-day adult    8 carcass, 20-day adult    6 ovary, virgin 4-day female    49 ovary, mated 4-day female    59 testis, mated 4-day male    13 accessory gland, mated 4-day male    9 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-12 hour embryonic stages. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    74 embryo 02-04hr    101 embryo 04-06hr    56 embryo 06-08hr    77 embryo 08-10hr    70 embryo 10-12hr    58 embryo 12-14hr    40 embryo 14-16hr    43 embryo 16-18hr    29 embryo 18-20hr    17 embryo 20-22hr    33 embryo 22-24hr    24 larva L1    15 larva L2    13 larva L3 12hr old    10 larva L3 puffstage 1-2    9 larva L3 puffstage 3-6    17 larva L3 puffstage 7-9    17 white prepupae new    19 white prepupae 12hr    24 white prepupae 24hr    33 pupae 2d postWPP    18 pupae 3d postWPP    9 pupae 4d postWPP    6 adult male 01day    9 adult male 05day    10 adult male 30day    9 adult female 01day    23 adult female 05day    38 adult female 30day    41 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (74) embryo 02-04hr  (101) embryo 04-06hr  (56) embryo 06-08hr  (77) embryo 08-10hr  (70) embryo 10-12hr  (58) embryo 12-14hr  (40) embryo 14-16hr  (43) embryo 16-18hr  (29) embryo 18-20hr    17 embryo 20-22hr  (33) embryo 22-24hr    24 larva L1    15 larva L2    13 larva L3 12hr old    10 larva L3 puffstage 1-2    9 larva L3 puffstage 3-6    17 larva L3 puffstage 7-9    17 white prepupae new    19 white prepupae 12hr    24 white prepupae 24hr  (33) pupae 2d postWPP    18 pupae 3d postWPP    9 pupae 4d postWPP    6 adult male 01day    9 adult male 05day    10 adult male 30day    9 adult female 01day    23 adult female 05day  (38) adult female 30day  (41) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    74 embryo 02-04hr  101 embryo 04-06hr    56 embryo 06-08hr    77 embryo 08-10hr    70 embryo 10-12hr    58 embryo 12-14hr    40 embryo 14-16hr    43 embryo 16-18hr    29 embryo 18-20hr    17 embryo 20-22hr    33 embryo 22-24hr    24 larva L1    15 larva L2    13 larva L3 12hr old    10 larva L3 puffstage 1-2    9 larva L3 puffstage 3-6    17 larva L3 puffstage 7-9    17 white prepupae new    19 white prepupae 12hr    24 white prepupae 24hr    33 pupae 2d postWPP    18 pupae 3d postWPP    9 pupae 4d postWPP    6 adult male 01day    9 adult male 05day    10 adult male 30day    9 adult female 01day    23 adult female 05day    38 adult female 30day    41 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    74 embryo 02-04hr    101 embryo 04-06hr    56 embryo 06-08hr    77 embryo 08-10hr    70 embryo 10-12hr    58 embryo 12-14hr    40 embryo 14-16hr    43 embryo 16-18hr    29 embryo 18-20hr    17 embryo 20-22hr    33 embryo 22-24hr    24 larva L1    15 larva L2    13 larva L3 12hr old    10 larva L3 puffstage 1-2    9 larva L3 puffstage 3-6    17 larva L3 puffstage 7-9    17 white prepupae new    19 white prepupae 12hr    24 white prepupae 24hr    33 pupae 2d postWPP    18 pupae 3d postWPP    9 pupae 4d postWPP    6 adult male 01day    9 adult male 05day    10 adult male 30day    9 adult female 01day    23 adult female 05day    38 adult female 30day    41 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    74 embryo 02-04hr    101 embryo 04-06hr    56 embryo 06-08hr    77 embryo 08-10hr    70 embryo 10-12hr    58 embryo 12-14hr    40 embryo 14-16hr    43 embryo 16-18hr    29 embryo 18-20hr    17 embryo 20-22hr    33 embryo 22-24hr    24 larva L1    15 larva L2    13 larva L3 12hr old    10 larva L3 puffstage 1-2    9 larva L3 puffstage 3-6    17 larva L3 puffstage 7-9    17 white prepupae new    19 white prepupae 12hr    24 white prepupae 24hr    33 pupae 2d postWPP    18 pupae 3d postWPP    9 pupae 4d postWPP    6 adult male 01day    9 adult male 05day    10 adult male 30day    9 adult female 01day    23 adult female 05day    38 adult female 30day    41 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (74) embryo 02-04hr  (101) embryo 04-06hr  (56) embryo 06-08hr  (77) embryo 08-10hr  (70) embryo 10-12hr  (58) embryo 12-14hr  (40) embryo 14-16hr  (43) embryo 16-18hr  29 embryo 18-20hr    17 embryo 20-22hr  (33) embryo 22-24hr    24 larva L1    15 larva L2    13 larva L3 12hr old    10 larva L3 puffstage 1-2    9 larva L3 puffstage 3-6    17 larva L3 puffstage 7-9    17 white prepupae new    19 white prepupae 12hr    24 white prepupae 24hr  (33) pupae 2d postWPP    18 pupae 3d postWPP    9 pupae 4d postWPP    6 adult male 01day    9 adult male 05day    10 adult male 30day    9 adult female 01day    23 adult female 05day  (38) adult female 30day  (41) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    74 embryo 02-04hr  101 embryo 04-06hr    56 embryo 06-08hr    77 embryo 08-10hr    70 embryo 10-12hr    58 embryo 12-14hr    40 embryo 14-16hr    43 embryo 16-18hr    29 embryo 18-20hr    17 embryo 20-22hr    33 embryo 22-24hr    24 larva L1    15 larva L2    13 larva L3 12hr old    10 larva L3 puffstage 1-2    9 larva L3 puffstage 3-6    17 larva L3 puffstage 7-9    17 white prepupae new    19 white prepupae 12hr    24 white prepupae 24hr    33 pupae 2d postWPP    18 pupae 3d postWPP    9 pupae 4d postWPP    6 adult male 01day    9 adult male 05day    10 adult male 30day    9 adult female 01day    23 adult female 05day    38 adult female 30day    41 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    74 embryo 02-04hr    101 embryo 04-06hr    56 embryo 06-08hr    77 embryo 08-10hr    70 embryo 10-12hr    58 embryo 12-14hr    40 embryo 14-16hr    43 embryo 16-18hr    29 embryo 18-20hr    17 embryo 20-22hr    33 embryo 22-24hr    24 larva L1    15 larva L2    13 larva L3 12hr old    10 larva L3 puffstage 1-2    9 larva L3 puffstage 3-6    17 larva L3 puffstage 7-9    17 white prepupae new    19 white prepupae 12hr    24 white prepupae 24hr    33 pupae 2d postWPP    18 pupae 3d postWPP    9 pupae 4d postWPP    6 adult male 01day    9 adult male 05day    10 adult male 30day    9 adult female 01day    23 adult female 05day    38 adult female 30day    41 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    26 Schneider line 2 Sg4    45 embryonic 1182-4H    27 embryonic GM2    16 embryonic Kc167    30 embryonic S1    32 embryonic S3    25 leg disc CME L1    42 wing disc CME-W2    18 wing disc ML-DmD8    23 wing disc ML-DmD9    37 wing disc ML-DmD16-c3    38 wing disc ML-DmD21    49 wing disc ML-DmD32    30 haltere disc ML-DmD17-c3    46 eye-antennal disc ML-DmD11    28 antennal disc ML-DmD20-c5    23 mixed discs ML-DmD4-c1    37 CNS ML-DmBG1-c1    42 CNS ML-DmBG2-c2    20 tumorous blood cells mbn2    14 ovary fGS/OSS    43 ovary OSC    46 ovary OSS    34 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  26 Schneider line 2 Sg4  (45) embryonic 1182-4H  (27) embryonic GM2    16 embryonic Kc167  (30) embryonic S1  (32) embryonic S3    25 leg disc CME L1  (42) wing disc CME-W2    18 wing disc ML-DmD8    23 wing disc ML-DmD9  (37) wing disc ML-DmD16-c3  (38) wing disc ML-DmD21  (49) wing disc ML-DmD32  (30) haltere disc ML-DmD17-c3  (46) eye-antennal disc ML-DmD11  (28) antennal disc ML-DmD20-c5    23 mixed discs ML-DmD4-c1  (37) CNS ML-DmBG1-c1  (42) CNS ML-DmBG2-c2    20 tumorous blood cells mbn2    14 ovary fGS/OSS  (43) ovary OSC  (46) ovary OSS  (34) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    26 Schneider line 2 Sg4    45 embryonic 1182-4H    27 embryonic GM2    16 embryonic Kc167    30 embryonic S1    32 embryonic S3    25 leg disc CME L1    42 wing disc CME-W2    18 wing disc ML-DmD8    23 wing disc ML-DmD9    37 wing disc ML-DmD16-c3    38 wing disc ML-DmD21    49 wing disc ML-DmD32    30 haltere disc ML-DmD17-c3    46 eye-antennal disc ML-DmD11    28 antennal disc ML-DmD20-c5    23 mixed discs ML-DmD4-c1    37 CNS ML-DmBG1-c1    42 CNS ML-DmBG2-c2    20 tumorous blood cells mbn2    14 ovary fGS/OSS    43 ovary OSC    46 ovary OSS    34 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    26 Schneider line 2 Sg4    45 embryonic 1182-4H    27 embryonic GM2    16 embryonic Kc167    30 embryonic S1    32 embryonic S3    25 leg disc CME L1    42 wing disc CME-W2    18 wing disc ML-DmD8    23 wing disc ML-DmD9    37 wing disc ML-DmD16-c3    38 wing disc ML-DmD21    49 wing disc ML-DmD32    30 haltere disc ML-DmD17-c3    46 eye-antennal disc ML-DmD11    28 antennal disc ML-DmD20-c5    23 mixed discs ML-DmD4-c1    37 CNS ML-DmBG1-c1    42 CNS ML-DmBG2-c2    20 tumorous blood cells mbn2    14 ovary fGS/OSS    43 ovary OSC    46 ovary OSS    34 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    26 Schneider line 2 Sg4    45 embryonic 1182-4H    27 embryonic GM2    16 embryonic Kc167    30 embryonic S1    32 embryonic S3    25 leg disc CME L1    42 wing disc CME-W2    18 wing disc ML-DmD8    23 wing disc ML-DmD9    37 wing disc ML-DmD16-c3    38 wing disc ML-DmD21    49 wing disc ML-DmD32    30 haltere disc ML-DmD17-c3    46 eye-antennal disc ML-DmD11    28 antennal disc ML-DmD20-c5    23 mixed discs ML-DmD4-c1    37 CNS ML-DmBG1-c1    42 CNS ML-DmBG2-c2    20 tumorous blood cells mbn2    14 ovary fGS/OSS    43 ovary OSC    46 ovary OSS    34 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  26 Schneider line 2 Sg4  (45) embryonic 1182-4H  27 embryonic GM2    16 embryonic Kc167  30 embryonic S1  32 embryonic S3    25 leg disc CME L1  (42) wing disc CME-W2    18 wing disc ML-DmD8    23 wing disc ML-DmD9  (37) wing disc ML-DmD16-c3  (38) wing disc ML-DmD21  (49) wing disc ML-DmD32  30 haltere disc ML-DmD17-c3  (46) eye-antennal disc ML-DmD11  28 antennal disc ML-DmD20-c5    23 mixed discs ML-DmD4-c1  (37) CNS ML-DmBG1-c1  (42) CNS ML-DmBG2-c2    20 tumorous blood cells mbn2    14 ovary fGS/OSS  (43) ovary OSC  (46) ovary OSS  (34) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    26 Schneider line 2 Sg4    45 embryonic 1182-4H    27 embryonic GM2    16 embryonic Kc167    30 embryonic S1    32 embryonic S3    25 leg disc CME L1    42 wing disc CME-W2    18 wing disc ML-DmD8    23 wing disc ML-DmD9    37 wing disc ML-DmD16-c3    38 wing disc ML-DmD21    49 wing disc ML-DmD32    30 haltere disc ML-DmD17-c3    46 eye-antennal disc ML-DmD11    28 antennal disc ML-DmD20-c5    23 mixed discs ML-DmD4-c1    37 CNS ML-DmBG1-c1    42 CNS ML-DmBG2-c2    20 tumorous blood cells mbn2    14 ovary fGS/OSS    43 ovary OSC    46 ovary OSS    34 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    26 Schneider line 2 Sg4    45 embryonic 1182-4H    27 embryonic GM2    16 embryonic Kc167    30 embryonic S1    32 embryonic S3    25 leg disc CME L1    42 wing disc CME-W2    18 wing disc ML-DmD8    23 wing disc ML-DmD9    37 wing disc ML-DmD16-c3    38 wing disc ML-DmD21    49 wing disc ML-DmD32    30 haltere disc ML-DmD17-c3    46 eye-antennal disc ML-DmD11    28 antennal disc ML-DmD20-c5    23 mixed discs ML-DmD4-c1    37 CNS ML-DmBG1-c1    42 CNS ML-DmBG2-c2    20 tumorous blood cells mbn2    14 ovary fGS/OSS    43 ovary OSC    46 ovary OSS    34 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    25 cold shock, 4-day adult    21 heat shock, 4-day adult    17 Cadmium 50 mM 6 hrs, larvae L3    7 Cadmium 50 mM 12 hrs, larvae L3    3 Cadmium 50 mM 48 hrs, 4-day adult    17 Cadmium 100 mM 48 hrs, 4-day adult    37 Copper 0.5 mM 12 hrs, larvae L3    16 Copper 15 mM 48 hrs, 4-day adult    20 Zinc 5 mM 12 hrs, larvae L3    14 Zinc 4.5 mM 48 hrs, 4-day adult    13 Ethanol 2.5% 3 hrs, larvae L3    35 Ethanol 5% 3 hrs, larvae L3    5 Ethanol 10% 3 hrs, larvae L3    6 Caffeine 1.5 mg/ml 4 hrs, larvae L3    4 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    34 Caffeine 25 mg/ml 48 hrs, 4-day adult    23 Paraquat 5 mM 48 hrs, 4-day adult    27 Paraquat 10 mM 48 hrs, 4-day adult    24 Rotenone 2 μg 12 hrs, larvae L3    5 Rotenone 8 μg 12 hrs, larvae L3    8 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    25 cold shock, 4-day adult    21 heat shock, 4-day adult    17 Cadmium 50 mM 6 hrs, larvae L3    7 Cadmium 50 mM 12 hrs, larvae L3    3 Cadmium 50 mM 48 hrs, 4-day adult    17 Cadmium 100 mM 48 hrs, 4-day adult  (37) Copper 0.5 mM 12 hrs, larvae L3    16 Copper 15 mM 48 hrs, 4-day adult    20 Zinc 5 mM 12 hrs, larvae L3    14 Zinc 4.5 mM 48 hrs, 4-day adult    13 Ethanol 2.5% 3 hrs, larvae L3  (35) Ethanol 5% 3 hrs, larvae L3    5 Ethanol 10% 3 hrs, larvae L3    6 Caffeine 1.5 mg/ml 4 hrs, larvae L3    4 Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (34) Caffeine 25 mg/ml 48 hrs, 4-day adult    23 Paraquat 5 mM 48 hrs, 4-day adult  (27) Paraquat 10 mM 48 hrs, 4-day adult    24 Rotenone 2 μg 12 hrs, larvae L3    5 Rotenone 8 μg 12 hrs, larvae L3    8 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    25 cold shock, 4-day adult    21 heat shock, 4-day adult    17 Cadmium 50 mM 6 hrs, larvae L3    7 Cadmium 50 mM 12 hrs, larvae L3    3 Cadmium 50 mM 48 hrs, 4-day adult    17 Cadmium 100 mM 48 hrs, 4-day adult    37 Copper 0.5 mM 12 hrs, larvae L3    16 Copper 15 mM 48 hrs, 4-day adult    20 Zinc 5 mM 12 hrs, larvae L3    14 Zinc 4.5 mM 48 hrs, 4-day adult    13 Ethanol 2.5% 3 hrs, larvae L3    35 Ethanol 5% 3 hrs, larvae L3    5 Ethanol 10% 3 hrs, larvae L3    6 Caffeine 1.5 mg/ml 4 hrs, larvae L3    4 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    34 Caffeine 25 mg/ml 48 hrs, 4-day adult    23 Paraquat 5 mM 48 hrs, 4-day adult    27 Paraquat 10 mM 48 hrs, 4-day adult    24 Rotenone 2 μg 12 hrs, larvae L3    5 Rotenone 8 μg 12 hrs, larvae L3    8 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    25 cold shock, 4-day adult    21 heat shock, 4-day adult    17 Cadmium 50 mM 6 hrs, larvae L3    7 Cadmium 50 mM 12 hrs, larvae L3    3 Cadmium 50 mM 48 hrs, 4-day adult    17 Cadmium 100 mM 48 hrs, 4-day adult    37 Copper 0.5 mM 12 hrs, larvae L3    16 Copper 15 mM 48 hrs, 4-day adult    20 Zinc 5 mM 12 hrs, larvae L3    14 Zinc 4.5 mM 48 hrs, 4-day adult    13 Ethanol 2.5% 3 hrs, larvae L3    35 Ethanol 5% 3 hrs, larvae L3    5 Ethanol 10% 3 hrs, larvae L3    6 Caffeine 1.5 mg/ml 4 hrs, larvae L3    4 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    34 Caffeine 25 mg/ml 48 hrs, 4-day adult    23 Paraquat 5 mM 48 hrs, 4-day adult    27 Paraquat 10 mM 48 hrs, 4-day adult    24 Rotenone 2 μg 12 hrs, larvae L3    5 Rotenone 8 μg 12 hrs, larvae L3    8 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    25 cold shock, 4-day adult    21 heat shock, 4-day adult    17 Cadmium 50 mM 6 hrs, larvae L3    7 Cadmium 50 mM 12 hrs, larvae L3    3 Cadmium 50 mM 48 hrs, 4-day adult    17 Cadmium 100 mM 48 hrs, 4-day adult    37 Copper 0.5 mM 12 hrs, larvae L3    16 Copper 15 mM 48 hrs, 4-day adult    20 Zinc 5 mM 12 hrs, larvae L3    14 Zinc 4.5 mM 48 hrs, 4-day adult    13 Ethanol 2.5% 3 hrs, larvae L3    35 Ethanol 5% 3 hrs, larvae L3    5 Ethanol 10% 3 hrs, larvae L3    6 Caffeine 1.5 mg/ml 4 hrs, larvae L3    4 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    34 Caffeine 25 mg/ml 48 hrs, 4-day adult    23 Paraquat 5 mM 48 hrs, 4-day adult    27 Paraquat 10 mM 48 hrs, 4-day adult    24 Rotenone 2 μg 12 hrs, larvae L3    5 Rotenone 8 μg 12 hrs, larvae L3    8 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    25 cold shock, 4-day adult    21 heat shock, 4-day adult    17 Cadmium 50 mM 6 hrs, larvae L3    7 Cadmium 50 mM 12 hrs, larvae L3    3 Cadmium 50 mM 48 hrs, 4-day adult    17 Cadmium 100 mM 48 hrs, 4-day adult  (37) Copper 0.5 mM 12 hrs, larvae L3    16 Copper 15 mM 48 hrs, 4-day adult    20 Zinc 5 mM 12 hrs, larvae L3    14 Zinc 4.5 mM 48 hrs, 4-day adult    13 Ethanol 2.5% 3 hrs, larvae L3  (35) Ethanol 5% 3 hrs, larvae L3    5 Ethanol 10% 3 hrs, larvae L3    6 Caffeine 1.5 mg/ml 4 hrs, larvae L3    4 Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (34) Caffeine 25 mg/ml 48 hrs, 4-day adult    23 Paraquat 5 mM 48 hrs, 4-day adult  27 Paraquat 10 mM 48 hrs, 4-day adult    24 Rotenone 2 μg 12 hrs, larvae L3    5 Rotenone 8 μg 12 hrs, larvae L3    8 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    25 cold shock, 4-day adult    21 heat shock, 4-day adult    17 Cadmium 50 mM 6 hrs, larvae L3    7 Cadmium 50 mM 12 hrs, larvae L3    3 Cadmium 50 mM 48 hrs, 4-day adult    17 Cadmium 100 mM 48 hrs, 4-day adult    37 Copper 0.5 mM 12 hrs, larvae L3    16 Copper 15 mM 48 hrs, 4-day adult    20 Zinc 5 mM 12 hrs, larvae L3    14 Zinc 4.5 mM 48 hrs, 4-day adult    13 Ethanol 2.5% 3 hrs, larvae L3    35 Ethanol 5% 3 hrs, larvae L3    5 Ethanol 10% 3 hrs, larvae L3    6 Caffeine 1.5 mg/ml 4 hrs, larvae L3    4 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    34 Caffeine 25 mg/ml 48 hrs, 4-day adult    23 Paraquat 5 mM 48 hrs, 4-day adult    27 Paraquat 10 mM 48 hrs, 4-day adult    24 Rotenone 2 μg 12 hrs, larvae L3    5 Rotenone 8 μg 12 hrs, larvae L3    8 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    25 cold shock, 4-day adult    21 heat shock, 4-day adult    17 Cadmium 50 mM 6 hrs, larvae L3    7 Cadmium 50 mM 12 hrs, larvae L3    3 Cadmium 50 mM 48 hrs, 4-day adult    17 Cadmium 100 mM 48 hrs, 4-day adult    37 Copper 0.5 mM 12 hrs, larvae L3    16 Copper 15 mM 48 hrs, 4-day adult    20 Zinc 5 mM 12 hrs, larvae L3    14 Zinc 4.5 mM 48 hrs, 4-day adult    13 Ethanol 2.5% 3 hrs, larvae L3    35 Ethanol 5% 3 hrs, larvae L3    5 Ethanol 10% 3 hrs, larvae L3    6 Caffeine 1.5 mg/ml 4 hrs, larvae L3    4 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    34 Caffeine 25 mg/ml 48 hrs, 4-day adult    23 Paraquat 5 mM 48 hrs, 4-day adult    27 Paraquat 10 mM 48 hrs, 4-day adult    24 Rotenone 2 μg 12 hrs, larvae L3    5 Rotenone 8 μg 12 hrs, larvae L3    8 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_17 mE1_20_mRNA_expression_cluster_03
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0036340 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG11274-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable, with Scer\GAL4pnr-MD237 SRm160GD1618 Other Phenotypes Allele body color defective, with Scer\GAL4pnr-MD237 SRm160GD1618 visible, with Scer\GAL4pnr-MD237 SRm160GD1618 Phenotype manifest in Allele mesothoracic tergum, with Scer\GAL4pnr-MD237 SRm160GD1618 trichogen cell, with Scer\GAL4pnr-MD237 SRm160GD1618
Classical Alleles ( 1 )
For All Classical Alleles Show
Allele of SRm160 Class Mutagen Stocks Known lesion SRm160G18603 P-element activity 1 --
Alleles Carried on Transgenic Constructs ( 5 )
For All Alleles Carried on Transgenic Constructs Show
Allele of SRm160 Class Mutagen Stocks Known lesion SRm160GD1618 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes SRm160GL00538 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes SRm160KK108396 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes SRm160dsRNA.cGa in vitro construct - RNAi 0 Yes SRm160NIG.11274R in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(3L)Exel6261 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD1618} NA P{KK108396} NA P{NIG.11274R} NA P{TRiP.GL00538} NA
Insertions
	Type of insertions Name Expression data insertion of mobile activating element P{EP}SRm160G18603 NA
Gene Ontology: Function, Process & Cellular Component ( 5 unique terms )
Terms Based on Experimental Evidence ( 2 terms )
Molecular Function ( 0 terms)
Biological Process ( 0 terms)
Cellular Component
CV term Evidence References
catalytic step 2 spliceosome inferred from direct assay (Herold et al., 2009) precatalytic spliceosome inferred from direct assay (Herold et al., 2009)
Terms Based on Predictions or Assertions ( 3 terms )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
mRNA processing inferred from electronic annotation with InterPro:IPR002483 (FlyBase Curators et al., 2004-) mRNA splicing, via spliceosome inferred by curator from GO:0071011|GO:0071013 (Herold et al., 2009)
Cellular Component
CV term Evidence References
exon-exon junction complex traceable author statement (Gatfield et al., 2003)
Sequence Ontology: Class of Gene
	gene_with_edited_transcript (Graveley et al., 2011) nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
protein-protein
Interacting group Assay References
SRm160 - CG13144 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) SRm160 - CG14718 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) SRm160 - CG33695 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) SRm160 - CalpA anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) SRm160 - CkIIα anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) SRm160 - Irp-1A anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) SRm160 - Ssu72 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23)
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions SRm160 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 64828 DroID - A comprehensive database of gene and protein interactions. • FBgn0036340 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 39483
Orthologs
OrthoDB Orthologs (38) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG64J34P Dipteran inclusive ortholog search EOG6CC49R Insect inclusive ortholog search EOG6V4257 Arthropod inclusive ortholog search EOG6DR7VT Metazoa inclusive ortholog search EOG6H1PQQ
Orthologs in Drosophila Species (EOG64J34P)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\SRm160     Drosophila simulans   Dsim\GD14425 Y   Drosophila sechellia   Dsec\GM25393 Y   Drosophila erecta   Dere\GG15622 Y   Drosophila yakuba   Dyak\GE21947 Y   Drosophila ananassae   Dana\GF24062 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA23761 Y   Drosophila persimilis   Dper\GL25328     Drosophila willistoni   Dwil\GK17424 Y   Drosophila virilis   Dvir\GJ13461 Y   Drosophila mojavensis   Dmoj\GI11751 Y   Drosophila grimshawi   Dgri\GH17142 Y
Orthologs in non-Drosophila Dipterans (EOG6CC49R)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL017526   Anopheles gambiae Malaria mosquito  Agam\AGAP005366   Anopheles gambiae Malaria mosquito  Agam\AGAP000961   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ003014
Orthologs in non-Dipteran Insects (EOG6V4257)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\GB51054   Apis mellifera Western honey bee  Amel\GB51052   Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG011281   Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH14372   Atta cephalotes Leafcutter ant  Acep\ACEP26238   Linepithema humile Argentine ant  Lhum\LH13678   Linepithema humile Argentine ant  Lhum\LH13679   Pogonomyrmex barbatus Red harvester ant  Pbar\PB16932   Solenopsis invicta Red fire ant  Sinv\SINV14061   Acyrthosiphon pisum Pea aphid  Apim\ACYPI001601   Bombyx mori Silkmoth  Bmor\BGIBMGA000312   Pediculus humanus Human body louse  Phum\PHUM150090   Tribolium castaneum Red flour beetle  Tcas\TC013178
Orthologs in non-Insect Arthropods (EOG6DR7VT)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\JGI_V11_313769   Ixodes scapularis Deer tick  Isca\ISCW013151
Orthologs in non-Arthropod Metazoa (EOG6H1PQQ)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Caenorhabditis elegans Nematode  Cele\rsr-1   Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_019555gn   Danio rerio Zebrafish  Drer\srrm1   Gallus gallus Domestic chicken  Ggal\SRRM1   Mus musculus House mouse  Mmus\Srrm1   Rattus norvegicus Norway rat  Rnor\Srrm1   Homo sapiens Human  Hsap\SRRM1
Human Orthologs (1)
Gene OMIM HGNC Hsap\SRRM1
AAA Orthologs (10) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD14425 Drosophila sechellia Dsec\GM25393 Drosophila erecta Dere\GG15622 Drosophila yakuba Dyak\GE21947 Drosophila ananassae Dana\GF24062 Drosophila pseudoobscura pseudoobscura Dpse\GA23761 Drosophila willistoni Dwil\GK17424 Drosophila virilis Dvir\GJ13461 Drosophila mojavensis Dmoj\GI11751 Drosophila grimshawi Dgri\GH17142
Stocks & Reagents
Stocks Listed in FlyBase ( 4 )
Bloomington	26938 y1 w*; P{EP}SRm160G18603 36578 y1 sc* v1; P{TRiP.GL00538}attP2/TM3, Sb1
VDRC	v100751 P{KK108396}VIE-260B v6439 w1118; P{GD1618}v6439
Genomic Clones ( 1 )
	BACR08G07 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 79 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	RE71183
Other clones	FI04407
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	GH22280 GM29423 LD03795 LD15510 LD17438 LD25922 LD28048 LD33240 LD36872 LD37738 LD38796 LD42710 LD44424 LD45845 LD45933 LD46117 LD46476 LD46477 LD47448 RE10752 RE12490 RE16228 RE16943 RE19967 RE23189 RE35384 RE40462 RE42977 RE43757 RE44329 RE44837 RE44838 RE47912 RE50039 RE57545 RE58795 RE59604 RE60069 RE65260 RE69131 RE69752 RE69788 RE70013 RE71720 RE71820 RH32221 SD09204
Other clones	597 1829 4746 36582 105870 123956 190784 214377.37 214475.41 CK01.122D.E1 Dmel_dig_010814_0687_0418 Dmel_neb_013187_0315_2760 EC052364 EK093517 EK121247 EK123248 EK123726 EK147063 EK246757 EK293145 EP10629 EP16033 FGC022B12 HL01288 LD37248 RP004248799 RP004262254 RP004264061 RP004325160 RP004537066
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0036340 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 39483
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_140370 RefSeq (Proteins) • NP_648627 DDBJ / EMBL / GenBank • AAF49848 AAT94426 BI577496 BT015197 Entrez Gene - A searchable database of RefSeq genes. • 39483 UniProtKB/TrEMBL • Q6AWQ1 Q9VU43
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • PWI domain (IPR002483)
Linkouts
	BioGRID - A database of protein and genetic interactions • 64828 DroID - A comprehensive database of gene and protein interactions. • FBgn0036340 DRSC - Results from RNAi screens. • FBgn0036340 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0036340 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG11274-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0036340 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 39483 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 39483 modMine - Data generated by the modENCODE project. • FBgn0036340
Synonyms & Secondary IDs ( 3 )
Reported As
Symbol Synonym	CG11274 (Gatfield et al., 2003, Gatfield and Izaurralde, 2002, Mount and Salz, 2000, Giot et al., 2003, Ni et al., 2011.7.19, Keleman et al., 2009.8.5, Herold et al., 2009) SRm160 (Fan et al., 2007, Ashton-Beaucage and Therrien, 2011, Herold et al., 2009, Roignant and Treisman, 2010, Olson et al., 2007, Japanese National Institute of Genetics, 2012.5.21) SRM160 (Boucher et al., 2001)
Name Synonym	SRm160
Secondary FlyBase IDs
References ( 25 )
Generate a list of	All references relating to this gene ( 25 )
List References by type	Research paper  ( 8 ) Supplementary material  ( 5 ) Review  ( 1 ) Personal communication to FlyBase  ( 8 ) Abstract  ( 1 ) Stock list  ( 1 )
Recent research papers ( 1 )
	Ashton-Beaucage and Therrien, 2011, Fly 5(3): 224--233 The exon junction complex: A splicing factor for long intron containing transcripts? [FBrf0214715] Show all research papers ...
Recent reviews (0)
	All reviews listed in FlyBase were published before 2011 Show reviews ...