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Gene Dmel\Syx13

General Information
Symbol	Dmel\Syx13	Species	D. melanogaster
Name	Syntaxin 13	Annotation symbol	CG11278
Feature type	protein_coding_gene	FlyBase ID	FBgn0036341
Gene Model Status	Current	Stock availability	4 publicly available
Also Known As	ff16, l(3)01470
Genomic Location
Chromosome (arm)	3L	Recombination map	3-38.63
Cytogenetic map	69F6-69F6	Sequence location	3L:13,037,536..13,040,001 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene Syntaxin 13 is referred to in FlyBase by the symbol Dmel\Syx13 (CG11278, FBgn0036341). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: SNAP receptor activity. There is experimental evidence that it is involved in the biological process: cytokinesis after mitosis; female meiosis; mitosis; male meiosis; cytokinesis after meiosis I. 5 alleles are reported. The phenotypes of these alleles are annotated with: organ system; multicellular structure; anatomical structure; ovariole; cell cycle; multi-tissue structure; cellular component organization or biogenesis; organelle; spermatozoon; sense organ; karyosome. It has one annotated transcript and one annotated polypeptide. Protein features are: Syntaxin, N-terminal; Syntaxin/epimorphin, conserved site; Target SNARE coiled-coil domain; t-SNARE. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages, during late larval stages, during early pupal stages. Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult tissues/organs expressed at moderate levels. Expression at high levels in the following post-embryonic organs or tissues: larval midgut, larval fat body. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, larval carcass. Comments on Affy2 ProbeSet: ProbeSet 1635186_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of Syx13. Gene sequence location is 3L:13037536..13040001.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2011_10
FB2012_01	Sequence features BKN31650 HFA09836 BKN46222
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 69F6-69F6   Limits computationally determined from genome sequence between P{lacW}RpS12s2783 and P{PZ}l(3)0422004220&P{lacW}l(3)j10B6j10B6
Experimentally Determined Cytological Location
Cytogenetic map Notes References 70A1-70A2   (determined by in situ hybridisation)   (Spradling et al., 1999) 70A1-70A2     (BDGP Project Members, 1994-1999)
Experimentally Determined Recombination Data
Location	3-38.63 (Fedorova et al., 2001)
Left of (cM)	th (Fedorova et al., 2001)
Right of (cM)	h (Fedorova et al., 2001)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\Syx13 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) Syx13-RA FBtr0075886  NM_079330   1493   284
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein Syx13-PA   FBpp0075620   31.5   284   7.35     NP_524054   AAF49845
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Target SNARE coiled-coil domain (IPR000727) Syntaxin, N-terminal (IPR006011) Syntaxin/epimorphin, conserved site (IPR006012) t-SNARE (IPR010989)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA948900   AE014296 AAF49845   AI293697   AI514540   AQ026170   AW942764   AY069551 AAL39696   BG636687   BI213981   BI228391   BI229033   BI234103   BI234257   BI364142   BI566845   BI583535   BI625907   BI628729   BI637583   BI641976   CK132015   CO188280   CO194735   CO269561   CO272016   CO272017   CO277704   CO292903   CO301734   CO303380   CO304948   CO326851   CO328608   CO330252   CO336472   CO342626   EC077070   EC077198   EC083636   EC232740   EC244377   EC247036   EC250762   EC258390   EC260150   EC261445   EV599528   GH739313   GH741012   GH742021   GH742680   GH744066   GH744930   GH745659   GH746226   GH761972   GH762572   GH764083   GH766531   GH767995   GH769037
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9VU45
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0036341    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0036341 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages, during late larval stages, during early pupal stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0036341 expression level Developmental Stage   Expression Level embryo 00-02hr    5187 embryo 02-04hr    2460 embryo 04-06hr    1033 embryo 06-08hr    1228 embryo 08-10hr    1529 embryo 10-12hr    2075 embryo 12-14hr    1541 embryo 14-16hr    1621 embryo 16-18hr    1443 embryo 18-20hr    1360 embryo 20-22hr    1175 embryo 22-24hr    1029 larva L1    1155 larva L2    987 larva L3 12hr old    947 larva L3 puffstage 1-2    1702 larva L3 puffstage 3-6    2638 larva L3 puffstage 7-9    5401 white prepupae new    7652 white prepupae 12hr    2711 white prepupae 24hr    2207 pupae 2d postWPP    1577 pupae 3d postWPP    1117 pupae 4d postWPP    1321 adult male 01day    1119 adult male 05day    1194 adult male 30day    1048 adult female 01day    1999 adult female 05day    2632 adult female 30day    3057 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (5187) embryo 02-04hr  (2460) embryo 04-06hr  (1033) embryo 06-08hr  (1228) embryo 08-10hr  (1529) embryo 10-12hr  (2075) embryo 12-14hr  (1541) embryo 14-16hr  (1621) embryo 16-18hr  (1443) embryo 18-20hr  (1360) embryo 20-22hr  (1175) embryo 22-24hr  (1029) larva L1  (1155) larva L2  (987) larva L3 12hr old  (947) larva L3 puffstage 1-2  (1702) larva L3 puffstage 3-6  (2638) larva L3 puffstage 7-9  (5401) white prepupae new  (7652) white prepupae 12hr  (2711) white prepupae 24hr  (2207) pupae 2d postWPP  (1577) pupae 3d postWPP  (1117) pupae 4d postWPP  (1321) adult male 01day  (1119) adult male 05day  (1194) adult male 30day  (1048) adult female 01day  (1999) adult female 05day  (2632) adult female 30day  (3057) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (5187) embryo 02-04hr  (2460) embryo 04-06hr    1033 embryo 06-08hr    1228 embryo 08-10hr  (1529) embryo 10-12hr  (2075) embryo 12-14hr  (1541) embryo 14-16hr  (1621) embryo 16-18hr  1443 embryo 18-20hr    1360 embryo 20-22hr    1175 embryo 22-24hr    1029 larva L1    1155 larva L2    987 larva L3 12hr old    947 larva L3 puffstage 1-2  (1702) larva L3 puffstage 3-6  (2638) larva L3 puffstage 7-9  (5401) white prepupae new  (7652) white prepupae 12hr  (2711) white prepupae 24hr  (2207) pupae 2d postWPP  (1577) pupae 3d postWPP    1117 pupae 4d postWPP    1321 adult male 01day    1119 adult male 05day    1194 adult male 30day    1048 adult female 01day  (1999) adult female 05day  (2632) adult female 30day  (3057) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    5187 embryo 02-04hr    2460 embryo 04-06hr    1033 embryo 06-08hr    1228 embryo 08-10hr    1529 embryo 10-12hr    2075 embryo 12-14hr    1541 embryo 14-16hr    1621 embryo 16-18hr    1443 embryo 18-20hr    1360 embryo 20-22hr    1175 embryo 22-24hr    1029 larva L1    1155 larva L2    987 larva L3 12hr old    947 larva L3 puffstage 1-2    1702 larva L3 puffstage 3-6    2638 larva L3 puffstage 7-9    5401 white prepupae new    7652 white prepupae 12hr    2711 white prepupae 24hr    2207 pupae 2d postWPP    1577 pupae 3d postWPP    1117 pupae 4d postWPP    1321 adult male 01day    1119 adult male 05day    1194 adult male 30day    1048 adult female 01day    1999 adult female 05day    2632 adult female 30day    3057 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    5187 embryo 02-04hr    2460 embryo 04-06hr    1033 embryo 06-08hr    1228 embryo 08-10hr    1529 embryo 10-12hr    2075 embryo 12-14hr    1541 embryo 14-16hr    1621 embryo 16-18hr    1443 embryo 18-20hr    1360 embryo 20-22hr    1175 embryo 22-24hr    1029 larva L1    1155 larva L2    987 larva L3 12hr old    947 larva L3 puffstage 1-2    1702 larva L3 puffstage 3-6    2638 larva L3 puffstage 7-9    5401 white prepupae new    7652 white prepupae 12hr    2711 white prepupae 24hr    2207 pupae 2d postWPP    1577 pupae 3d postWPP    1117 pupae 4d postWPP    1321 adult male 01day    1119 adult male 05day    1194 adult male 30day    1048 adult female 01day    1999 adult female 05day    2632 adult female 30day    3057 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0036341 expression level Developmental Stage   Expression Level embryo 00-02hr    5187 embryo 02-04hr    2460 embryo 04-06hr    1033 embryo 06-08hr    1228 embryo 08-10hr    1529 embryo 10-12hr    2075 embryo 12-14hr    1541 embryo 14-16hr    1621 embryo 16-18hr    1443 embryo 18-20hr    1360 embryo 20-22hr    1175 embryo 22-24hr    1029 larva L1    1155 larva L2    987 larva L3 12hr old    947 larva L3 puffstage 1-2    1702 larva L3 puffstage 3-6    2638 larva L3 puffstage 7-9    5401 white prepupae new    7652 white prepupae 12hr    2711 white prepupae 24hr    2207 pupae 2d postWPP    1577 pupae 3d postWPP    1117 pupae 4d postWPP    1321 adult male 01day    1119 adult male 05day    1194 adult male 30day    1048 adult female 01day    1999 adult female 05day    2632 adult female 30day    3057 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (5187) embryo 02-04hr  (2460) embryo 04-06hr  (1033) embryo 06-08hr  (1228) embryo 08-10hr  (1529) embryo 10-12hr  (2075) embryo 12-14hr  (1541) embryo 14-16hr  (1621) embryo 16-18hr  (1443) embryo 18-20hr  (1360) embryo 20-22hr  (1175) embryo 22-24hr  (1029) larva L1  (1155) larva L2  (987) larva L3 12hr old  (947) larva L3 puffstage 1-2  (1702) larva L3 puffstage 3-6  (2638) larva L3 puffstage 7-9  (5401) white prepupae new  (7652) white prepupae 12hr  (2711) white prepupae 24hr  (2207) pupae 2d postWPP  (1577) pupae 3d postWPP  (1117) pupae 4d postWPP  (1321) adult male 01day  (1119) adult male 05day  (1194) adult male 30day  (1048) adult female 01day  (1999) adult female 05day  (2632) adult female 30day  (3057) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (5187) embryo 02-04hr  2460 embryo 04-06hr    1033 embryo 06-08hr    1228 embryo 08-10hr  1529 embryo 10-12hr  2075 embryo 12-14hr  1541 embryo 14-16hr  1621 embryo 16-18hr  1443 embryo 18-20hr    1360 embryo 20-22hr    1175 embryo 22-24hr    1029 larva L1    1155 larva L2    987 larva L3 12hr old    947 larva L3 puffstage 1-2  1702 larva L3 puffstage 3-6  (2638) larva L3 puffstage 7-9  (5401) white prepupae new  (7652) white prepupae 12hr  (2711) white prepupae 24hr  2207 pupae 2d postWPP  1577 pupae 3d postWPP    1117 pupae 4d postWPP    1321 adult male 01day    1119 adult male 05day    1194 adult male 30day    1048 adult female 01day  1999 adult female 05day  (2632) adult female 30day  (3057) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    5187 embryo 02-04hr    2460 embryo 04-06hr    1033 embryo 06-08hr    1228 embryo 08-10hr    1529 embryo 10-12hr    2075 embryo 12-14hr    1541 embryo 14-16hr    1621 embryo 16-18hr    1443 embryo 18-20hr    1360 embryo 20-22hr    1175 embryo 22-24hr    1029 larva L1    1155 larva L2    987 larva L3 12hr old    947 larva L3 puffstage 1-2    1702 larva L3 puffstage 3-6    2638 larva L3 puffstage 7-9    5401 white prepupae new    7652 white prepupae 12hr    2711 white prepupae 24hr    2207 pupae 2d postWPP    1577 pupae 3d postWPP    1117 pupae 4d postWPP    1321 adult male 01day    1119 adult male 05day    1194 adult male 30day    1048 adult female 01day    1999 adult female 05day    2632 adult female 30day    3057 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    5187 embryo 02-04hr    2460 embryo 04-06hr    1033 embryo 06-08hr    1228 embryo 08-10hr    1529 embryo 10-12hr    2075 embryo 12-14hr    1541 embryo 14-16hr    1621 embryo 16-18hr    1443 embryo 18-20hr    1360 embryo 20-22hr    1175 embryo 22-24hr    1029 larva L1    1155 larva L2    987 larva L3 12hr old    947 larva L3 puffstage 1-2    1702 larva L3 puffstage 3-6    2638 larva L3 puffstage 7-9    5401 white prepupae new    7652 white prepupae 12hr    2711 white prepupae 24hr    2207 pupae 2d postWPP    1577 pupae 3d postWPP    1117 pupae 4d postWPP    1321 adult male 01day    1119 adult male 05day    1194 adult male 30day    1048 adult female 01day    1999 adult female 05day    2632 adult female 30day    3057 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0036341    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0036341 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult tissues/organs expressed at moderate levels. Expression at high levels in the following post-embryonic organs or tissues: larval midgut, larval fat body. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, larval carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0036341 expression level Tissue   Expression Level Larval Central Nervous System    173.7 Larval Midgut    623.1 Larval Hindgut    214.6 Larval Malpighian Tubules    452.3 Larval Fat Body    939 Larval Salivary Gland    164.1 Larval Trachea    186.025 Larval Carcass    199.475 Adult Head    176.4 Adult Eye    346.25 Adult Brain    202.6 Adult Thoracic-Abdominal Ganglion    206.5 Adult Crop    135.9 Adult Midgut    284.7 Adult Hindgut    137.1 Adult Malpighian Tubules    162 Adult Fat Body    121.8 Adult Salivary Gland    116.3 Adult Heart    220.8 Adult VirginFemale Spermatheca    163.7 Adult InseminatedFemale Spermatheca    164.5 Adult Ovary    320.6 Adult Testis    55.2 Adult Male Accessory Gland    93.2 Adult Carcass    90.7 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    173.7 Larval Midgut  (623.1) Larval Hindgut    214.6 Larval Malpighian Tubules    452.3 Larval Fat Body  (939) Larval Salivary Gland    164.1 Larval Trachea    186.025 Larval Carcass    199.475 Adult Head    176.4 Adult Eye    346.25 Adult Brain    202.6 Adult Thoracic-Abdominal Ganglion    206.5 Adult Crop    135.9 Adult Midgut    284.7 Adult Hindgut    137.1 Adult Malpighian Tubules    162 Adult Fat Body    121.8 Adult Salivary Gland    116.3 Adult Heart    220.8 Adult VirginFemale Spermatheca    163.7 Adult InseminatedFemale Spermatheca    164.5 Adult Ovary    320.6 Adult Testis    55.2 Adult Male Accessory Gland    93.2 Adult Carcass    90.7 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    173.7 Larval Midgut    623.1 Larval Hindgut    214.6 Larval Malpighian Tubules    452.3 Larval Fat Body    939 Larval Salivary Gland    164.1 Larval Trachea    186.025 Larval Carcass    199.475 Adult Head    176.4 Adult Eye    346.25 Adult Brain    202.6 Adult Thoracic-Abdominal Ganglion    206.5 Adult Crop    135.9 Adult Midgut    284.7 Adult Hindgut    137.1 Adult Malpighian Tubules    162 Adult Fat Body    121.8 Adult Salivary Gland    116.3 Adult Heart    220.8 Adult VirginFemale Spermatheca    163.7 Adult InseminatedFemale Spermatheca    164.5 Adult Ovary    320.6 Adult Testis    55.2 Adult Male Accessory Gland    93.2 Adult Carcass    90.7 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    173.7 Larval Midgut    623.1 Larval Hindgut    214.6 Larval Malpighian Tubules    452.3 Larval Fat Body    939 Larval Salivary Gland    164.1 Larval Trachea    186.025 Larval Carcass    199.475 Adult Head    176.4 Adult Eye    346.25 Adult Brain    202.6 Adult Thoracic-Abdominal Ganglion    206.5 Adult Crop    135.9 Adult Midgut    284.7 Adult Hindgut    137.1 Adult Malpighian Tubules    162 Adult Fat Body    121.8 Adult Salivary Gland    116.3 Adult Heart    220.8 Adult VirginFemale Spermatheca    163.7 Adult InseminatedFemale Spermatheca    164.5 Adult Ovary    320.6 Adult Testis    55.2 Adult Male Accessory Gland    93.2 Adult Carcass    90.7 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0036341 expression level Tissue   Expression Level Larval Central Nervous System    173.7 Larval Midgut    623.1 Larval Hindgut    214.6 Larval Malpighian Tubules    452.3 Larval Fat Body    939 Larval Salivary Gland    164.1 Larval Trachea    186.025 Larval Carcass    199.475 Adult Head    176.4 Adult Eye    346.25 Adult Brain    202.6 Adult Thoracic-Abdominal Ganglion    206.5 Adult Crop    135.9 Adult Midgut    284.7 Adult Hindgut    137.1 Adult Malpighian Tubules    162 Adult Fat Body    121.8 Adult Salivary Gland    116.3 Adult Heart    220.8 Adult VirginFemale Spermatheca    163.7 Adult InseminatedFemale Spermatheca    164.5 Adult Ovary    320.6 Adult Testis    55.2 Adult Male Accessory Gland    93.2 Adult Carcass    90.7 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    173.7 Larval Midgut  623.1 Larval Hindgut    214.6 Larval Malpighian Tubules    452.3 Larval Fat Body  (939) Larval Salivary Gland    164.1 Larval Trachea    186.025 Larval Carcass    199.475 Adult Head    176.4 Adult Eye    346.25 Adult Brain    202.6 Adult Thoracic-Abdominal Ganglion    206.5 Adult Crop    135.9 Adult Midgut    284.7 Adult Hindgut    137.1 Adult Malpighian Tubules    162 Adult Fat Body    121.8 Adult Salivary Gland    116.3 Adult Heart    220.8 Adult VirginFemale Spermatheca    163.7 Adult InseminatedFemale Spermatheca    164.5 Adult Ovary    320.6 Adult Testis    55.2 Adult Male Accessory Gland    93.2 Adult Carcass    90.7 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    173.7 Larval Midgut    623.1 Larval Hindgut    214.6 Larval Malpighian Tubules    452.3 Larval Fat Body    939 Larval Salivary Gland    164.1 Larval Trachea    186.025 Larval Carcass    199.475 Adult Head    176.4 Adult Eye    346.25 Adult Brain    202.6 Adult Thoracic-Abdominal Ganglion    206.5 Adult Crop    135.9 Adult Midgut    284.7 Adult Hindgut    137.1 Adult Malpighian Tubules    162 Adult Fat Body    121.8 Adult Salivary Gland    116.3 Adult Heart    220.8 Adult VirginFemale Spermatheca    163.7 Adult InseminatedFemale Spermatheca    164.5 Adult Ovary    320.6 Adult Testis    55.2 Adult Male Accessory Gland    93.2 Adult Carcass    90.7 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    173.7 Larval Midgut    623.1 Larval Hindgut    214.6 Larval Malpighian Tubules    452.3 Larval Fat Body    939 Larval Salivary Gland    164.1 Larval Trachea    186.025 Larval Carcass    199.475 Adult Head    176.4 Adult Eye    346.25 Adult Brain    202.6 Adult Thoracic-Abdominal Ganglion    206.5 Adult Crop    135.9 Adult Midgut    284.7 Adult Hindgut    137.1 Adult Malpighian Tubules    162 Adult Fat Body    121.8 Adult Salivary Gland    116.3 Adult Heart    220.8 Adult VirginFemale Spermatheca    163.7 Adult InseminatedFemale Spermatheca    164.5 Adult Ovary    320.6 Adult Testis    55.2 Adult Male Accessory Gland    93.2 Adult Carcass    90.7 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    176.4   NA  Eye    346.25   NA  Brain    202.6   173.7  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    206.5   NA  Crop    135.9   623.1  Midgut    284.7   214.6  Hindgut    137.1   452.3  Malpighian Tubules    162   939  Fat Body    121.8   164.1  Salivary Gland    116.3   NA  Heart    220.8   186.025  Trachea    NA   NA  VirginFemale Spermatheca    163.7   NA  InseminatedFemale Spermatheca    164.5   NA  Ovary    320.6   NA  Testis    55.2   NA  Male Accessory Gland    93.2   199.475  Carcass    90.7 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_23
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0036341 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG11278-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal | recessive Syx1301470 viable, with Scer\GAL4pnr-MD237 Syx13GD2449 Sterility Allele female sterile | recessive Syx13ff16 male sterile | recessive Syx13ff16 Other Phenotypes Allele meiotic cell cycle defective Syx13ff16 mitotic cell cycle defective Syx13ff16 visible | recessive Syx13ff16 Phenotype manifest in Allele chaeta Syx13ff16 egg chamber Syx13ff16 karyosome Syx13ff16 meiosis & nuclear chromosome | male Syx13ff16 meiotic anaphase I | male Syx13ff16 meiotic cell cycle | female Syx13ff16 meiotic cell cycle | male Syx13ff16 meiotic metaphase II | male Syx13ff16 meiotic telophase II | male Syx13ff16 mitotic cell cycle Syx13ff16 mitotic cell cycle & nuclear chromosome Syx13ff16 mitotic cell cycle & spindle Syx13ff16 mitotic metaphase Syx13ff16 nurse cell Syx13ff16 onion stage spermatid Syx13ff16 oocyte Syx13ff16 oocyte & spindle Syx13ff16 ovariole Syx13ff16 polytene chromosome chromocenter Syx13ff16 spermatozoon Syx13ff16
Classical Alleles ( 2 )
For All Classical Alleles Show
Allele of Syx13 Class Mutagen Stocks Known lesion Syx1301470 P-element activity 1 -- Syx13ff16 gamma ray 0 --
Alleles Carried on Transgenic Constructs ( 3 )
For All Alleles Carried on Transgenic Constructs Show
Allele of Syx13 Class Mutagen Stocks Known lesion Syx13GD2449 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes Syx13JF01920 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes Syx13KK111650 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes
Aneuploid Aberrations
Not disrupted in	Df(3L)Ly (Spradling et al., 1999, BDGP Project Members, 1994-1999)
Disrupted in	Df(3L)Exel6261 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD2449} NA P{KK111650} NA P{TRiP.JF01920} NA
Insertions
	Type of insertions Name Expression data insertion of enhancer trap P{PZ}Syx1301470 No insertion of mobile activating element P{GSV1}EP-872EP-872 NA
Gene Ontology: Function, Process & Cellular Component ( 11 unique terms )
Terms Based on Experimental Evidence ( 5 terms )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
cytokinesis after meiosis I inferred from mutant phenotype (Nokkala et al., 2002) cytokinesis after mitosis inferred from mutant phenotype (Nokkala et al., 2002) female meiosis inferred from mutant phenotype (Fedorova et al., 2001) male meiosis inferred from mutant phenotype (Fedorova et al., 2001) mitosis inferred from mutant phenotype (Fedorova et al., 2001)
Cellular Component ( 0 terms)
Terms Based on Predictions or Assertions ( 6 terms )
Molecular Function
CV term Evidence References
SNAP receptor activity inferred from sequence or structural similarity (Littleton, 2000) inferred from sequence or structural similarity with EMBL:AF044581 (McLennan, 2001.5.22)
Biological Process
CV term Evidence References
intracellular protein transport inferred from electronic annotation with InterPro:IPR006012 (FlyBase Curators et al., 2004-) neurotransmitter secretion inferred from sequence or structural similarity with EMBL:AF044581 (McLennan, 2001.5.22) synaptic vesicle docking involved in exocytosis inferred from sequence or structural similarity (Littleton, 2000) vesicle-mediated transport inferred from sequence or structural similarity with EMBL:AF044581 (McLennan, 2001.5.22)
Cellular Component
CV term Evidence References
plasma membrane inferred from sequence or structural similarity (Littleton, 2000) inferred from sequence or structural similarity with EMBL:AF044581 (McLennan, 2001.5.22)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions Syx13 allele Gene References unspecified bchs (Simonsen et al., 2007)
External Data
Linkouts	DroID - A comprehensive database of gene and protein interactions. • FBgn0036341 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 39485
Orthologs
Genome-wide drosophilid orthologs	Dana\GF24028 Dere\GG15624 Dgri\GH17144 Dmoj\GI11753 Dper\GL25332 Dpse\GA10884 Dsec\GM25395 Dsim\GD14427 Dvir\GJ13463 Dwil\GK17426 Dyak\GE21949
Curated drosophilid orthologs	Dpse\GA10884
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL009398-PA Aedes aegypti (mosquito) AGAP011727-PA Anopheles gambiae (mosquito) XP_623620.2 Apis mellifera (honey bee) BGIBMGA010004-PA Bombyx mori (silk worm) CAL0002435 Candida albicans (a form of yeast) CAGL0G04807g Candida glabrata (haploid yeast) CPIJ015036 Culex pipens (mosquito) 214729 Capitella spl (polychaete worm) DEHA2F11506g Debaryomyces Hansenii (yeast) 299564 Daphnia pulex (daphnia) XP_650755 Entamoeba histolytica (anaerobic protozoan) ENSGACP00000018767 Gymnopilus aculeatus (mushroom) GL50803_3869 Giardia lamblia (flagellated protozoan) ISCW002586-PA Ixodes scapularis (deer tick) KLLA0E21759g Kluyveromyces lactis (yeast) 237001 Lottia gigantea (owl limpet) XP_001603158.1 Nasonia vitripennis (wasp) 5569 Ostreococcus tauri (green alga) PHUM003816-PA Pediculus humanus (human body louse) 72794 Phytophthora ramorum (sudden oak death pathogen) 84062 Phytophthora ramorum (sudden oak death pathogen) 142550 Phytophthora sojae (root rot pathogen) 155254 Phytophthora sojae (root rot pathogen) Smp_125640 Schistosoma mansoni (trematode parasite) SPBC31E1.04 Schizosaccharomyces pombe (fission yeast) XP_973359.1 Tribolium castaneum (red flour beetle) YALI0C22275g Yarrowia lipolytica (nonconventional yeast) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • NV14312 LH19260 ISCW002586 FBgn0239185 FBgn0219426 FBgn0219425 FBgn0200687 FBgn0186110 FBgn0180253 JGI_V11_299564 FBgn0070940 FBgn0162916 FBgn0134514 FBgn0134512 FBgn0124614 FBgn0107868 FBgn0101022 CPIJ015036 BGIBMGA010004 GB10021 AGAP011727 AAEL009398 PB22116 PHUM507070 GLEAN_07177
Stocks & Reagents
Stocks Listed in FlyBase ( 4 )
Bloomington	27984 y1 v1; P{TRiP.JF01920}attP2 11536 P{PZ}Syx1301470 ry506/TM3, ryRK Sb1 Ser1
VDRC	v102432 P{KK111650}VIE-260B v8361 w1118; P{GD2449}v8361
Genomic Clones ( 1 )
	BACR08G07 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 57 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	LD27581
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	LD41082 LP06889 LP13176 RE19649 RE25929 RE26730 RE29744 RE29931 RE49203 RH22168 RH36604 RH57255 RH66415 SD14453 SD19632 SD25669
Other clones	15207 15223 15748 72159 121143 124460 191885 214385.46 214563.43 557887 Dmel_neb_011286_0894_0991 EC39141 EK038948 EK095004 EK105462 EK105463 EK125926 EK182008 EK201162 EK241226 EK246764 EK291011 EK294822 EN12612 EP04743 EP15230 RP001010044 RP001011371 RP001022332 RP001022382 RP001022796 RP001024199 RP001035226 RP001039589 RP001044321 RP001048941 RP001053242 RP001053876 RP001054810 RP001055609
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0036341 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 39485
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of	Source for identity of: Syx13 CG11278 (McLennan, 2001.5.22)
Source for database merge of	Source for merge of: Syx13 l(3)01470 (FlyBase, 1996-)
Additional comments	Source for merge of Syx13 l(3)01470 was a shared cDNA (date:030206). (FlyBase, 1996-)
Other Comments
	dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology. (Kiger et al., 2003)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_079330 RefSeq (Proteins) • NP_524054 DDBJ / EMBL / GenBank • AA948900 AAF49845 AAL39696 AQ026170 AW942764 AY069551 Entrez Gene - A searchable database of RefSeq genes. • 39485 UniProtKB/TrEMBL • Q9VU45
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Target SNARE coiled-coil domain (IPR000727) Syntaxin, N-terminal (IPR006011) Syntaxin/epimorphin, conserved site (IPR006012) t-SNARE (IPR010989)
Linkouts
	DroID - A comprehensive database of gene and protein interactions. • FBgn0036341 DRSC - Results from RNAi screens. • FBgn0036341 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0036341 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG11278-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0036341 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 39485 InParanoid A subset of ortholog calls from InParanoid. • AAEL009398-PA Aedes aegypti (mosquito) AGAP011727-PA Anopheles gambiae (mosquito) XP_623620.2 Apis mellifera (honey bee) BGIBMGA010004-PA Bombyx mori (silk worm) CAL0002435 Candida albicans (a form of yeast) CAGL0G04807g Candida glabrata (haploid yeast) CPIJ015036 Culex pipens (mosquito) 214729 Capitella spl (polychaete worm) DEHA2F11506g Debaryomyces Hansenii (yeast) 299564 Daphnia pulex (daphnia) XP_650755 Entamoeba histolytica (anaerobic protozoan) ENSGACP00000018767 Gymnopilus aculeatus (mushroom) GL50803_3869 Giardia lamblia (flagellated protozoan) ISCW002586-PA Ixodes scapularis (deer tick) KLLA0E21759g Kluyveromyces lactis (yeast) 237001 Lottia gigantea (owl limpet) XP_001603158.1 Nasonia vitripennis (wasp) 5569 Ostreococcus tauri (green alga) PHUM003816-PA Pediculus humanus (human body louse) 72794 Phytophthora ramorum (sudden oak death pathogen) 84062 Phytophthora ramorum (sudden oak death pathogen) 142550 Phytophthora sojae (root rot pathogen) 155254 Phytophthora sojae (root rot pathogen) Smp_125640 Schistosoma mansoni (trematode parasite) SPBC31E1.04 Schizosaccharomyces pombe (fission yeast) XP_973359.1 Tribolium castaneum (red flour beetle) YALI0C22275g Yarrowia lipolytica (nonconventional yeast) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 39485 modMine - Data generated by the modENCODE project. • FBgn0036341 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • NV14312 LH19260 ISCW002586 FBgn0239185 FBgn0219426 FBgn0219425 FBgn0200687 FBgn0186110 FBgn0180253 JGI_V11_299564 FBgn0070940 FBgn0162916 FBgn0134514 FBgn0134512 FBgn0124614 FBgn0107868 FBgn0101022 CPIJ015036 BGIBMGA010004 GB10021 AGAP011727 AAEL009398 PB22116 PHUM507070 GLEAN_07177
Synonyms & Secondary IDs ( 15 )
Reported As
Symbol Synonym	CG11278 (Lu and Bilder, 2005, Molnar et al., 2006, Dorer et al., 2006, Keleman et al., 2009.8.5, Perkins et al., 2009) DmSyx13 (McLennan, 2001.5.22) Dm Syx13 (Littleton, 2000) ff16 (Fedorova et al., 2001, Chubykin, 2001) ff16 (69D1-70A2) (Nokkala et al., 2002) l(3)01470 (Spradling et al., 1999, BDGP Project Members, 1994-1999, ) SYN13 (Dorer et al., 2006) Syx (Wagh et al., 2006) Syx13 (Wilson et al., 2006, McClure and Schubiger, 2008, Morrison et al., 2008)
Name Synonym	dSyntaxin13 (Akbar et al., 2009) syntaxin (Dumstrei et al., 2003) Syntaxin (Nokkala et al., 2002, Kittel et al., 2006, Wagh et al., 2006, Hossain et al., 2008, Pereanu and Hartenstein, 2006) Syntaxin 13 (McLennan, 2001.5.22) syntaxin 13 (Simonsen et al., 2007) Syntaxin13 (Molnar et al., 2006)
Secondary FlyBase IDs
	FBgn0010751
References ( 35 )
Generate a list of	All references relating to this gene ( 35 )
List References by type	Research paper  ( 17 ) Supplementary material  ( 4 ) Personal communication to FlyBase  ( 7 ) Abstract  ( 2 ) FlyBase analysis  ( 2 ) Computer file  ( 2 ) Automatic genome annotation  ( 1 )
Recent research papers (0)
	All research papers listed in FlyBase were published before 2010 Show research papers ...