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Gene Dmel\CG10738

General Information
Symbol	Dmel\CG10738	Species	D. melanogaster
Name		Annotation symbol	CG10738
Feature type	protein_coding_gene	FlyBase ID	FBgn0036368
Gene Model Status	Current	Stock availability	3 publicly available
Genomic Location
Chromosome (arm)	3L	Recombination map
Cytogenetic map	70B1-70B1	Sequence location	3L:13,443,870..13,458,639 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG10738 (FBgn0036368). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: receptor activity; guanylate cyclase activity. Based on sequence similarity, it is predicted to be involved in the biological process: signal transduction. 4 alleles are reported. No phenotypic data is available. It has 4 annotated transcripts and 4 annotated polypeptides. Protein features are: Adenylyl cyclase class-3/4/guanylyl cyclase; Adenylyl cyclase class-3/4/guanylyl cyclase, conserved site; Extracellular ligand-binding receptor; Haem NO binding associated; Protein kinase, catalytic domain; Protein kinase-like domain; Serine-threonine/tyrosine-protein kinase. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of very low expression. Peak expression observed within 00-06 hour embryonic stages, during late pupal stages. Summary of FlyAtlas Anatomical Expression Data: Little or no expression detected in any larval or adult organs/tissues. Gene sequence location is 3L:13443870..13458639.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2012_01	Sequence features BKN50753 BKN50223 BKN33301 HFA09792
FB2011_10
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 70B1-70B1   Limits computationally determined from genome sequence between P{PZ}l(3)0422004220&P{lacW}l(3)j10B6j10B6 and P{PZ}stv00543
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG10738 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG10738-RC FBtr0302487  NM_140396   5115   1248 CG10738-RD FBtr0302488  NM_168547   5121   1250 CG10738-RE FBtr0304791     5082   1237 CG10738-RF FBtr0304792     5076   1235
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG10738-PC   FBpp0291649   140.3   1248   8.35     NP_648653   AAN11824 CG10738-PD   FBpp0291650   140.6   1250   8.36     NP_729905   AAF49811 CG10738-PE   FBpp0293331   139.0   1237   8.24       CG10738-PF   FBpp0293332   138.7   1235   8.24
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Protein kinase, catalytic domain (IPR000719) Adenylyl cyclase class-3/4/guanylyl cyclase (IPR001054) Extracellular ligand-binding receptor (IPR001828) Protein kinase-like domain (IPR011009) Adenylyl cyclase class-3/4/guanylyl cyclase, conserved site (IPR018297) Serine-threonine/tyrosine-protein kinase (IPR001245) Haem NO binding associated (IPR011645)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE014296 AAF49811   AE014296 AAN11824   BT099705   EC051502   EC051991   EC054003   EC055376   EC056448   EL874031   EL874032   EL874273   EL874831   EL874832   EL874960   EL874961   EV581938   FL502457   GH291252   GH291302   GH291358   GO271079   GO271155   GR705843
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q8IQK2 Q9VU79
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0036368    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0036368 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of very low expression. Peak expression observed within 00-06 hour embryonic stages, during late pupal stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0036368 expression level Developmental Stage   Expression Level embryo 00-02hr    426 embryo 02-04hr    117 embryo 04-06hr    42 embryo 06-08hr    30 embryo 08-10hr    31 embryo 10-12hr    56 embryo 12-14hr    78 embryo 14-16hr    207 embryo 16-18hr    257 embryo 18-20hr    255 embryo 20-22hr    236 embryo 22-24hr    253 larva L1    255 larva L2    357 larva L3 12hr old    150 larva L3 puffstage 1-2    52 larva L3 puffstage 3-6    44 larva L3 puffstage 7-9    29 white prepupae new    45 white prepupae 12hr    71 white prepupae 24hr    87 pupae 2d postWPP    243 pupae 3d postWPP    750 pupae 4d postWPP    148 adult male 01day    76 adult male 05day    52 adult male 30day    45 adult female 01day    195 adult female 05day    286 adult female 30day    245 Expression Level Scale  None   Extremely low   Very low   Low   Moderate  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (426) embryo 02-04hr  (117) embryo 04-06hr    42 embryo 06-08hr    30 embryo 08-10hr    31 embryo 10-12hr    56 embryo 12-14hr    78 embryo 14-16hr  (207) embryo 16-18hr  (257) embryo 18-20hr  (255) embryo 20-22hr  (236) embryo 22-24hr  (253) larva L1  (255) larva L2  (357) larva L3 12hr old  (150) larva L3 puffstage 1-2    52 larva L3 puffstage 3-6    44 larva L3 puffstage 7-9    29 white prepupae new    45 white prepupae 12hr    71 white prepupae 24hr    87 pupae 2d postWPP  (243) pupae 3d postWPP  (750) pupae 4d postWPP  (148) adult male 01day    76 adult male 05day    52 adult male 30day    45 adult female 01day  (195) adult female 05day  (286) adult female 30day  (245) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    426 embryo 02-04hr    117 embryo 04-06hr    42 embryo 06-08hr    30 embryo 08-10hr    31 embryo 10-12hr    56 embryo 12-14hr    78 embryo 14-16hr    207 embryo 16-18hr    257 embryo 18-20hr    255 embryo 20-22hr    236 embryo 22-24hr    253 larva L1    255 larva L2    357 larva L3 12hr old    150 larva L3 puffstage 1-2    52 larva L3 puffstage 3-6    44 larva L3 puffstage 7-9    29 white prepupae new    45 white prepupae 12hr    71 white prepupae 24hr    87 pupae 2d postWPP    243 pupae 3d postWPP    750 pupae 4d postWPP    148 adult male 01day    76 adult male 05day    52 adult male 30day    45 adult female 01day    195 adult female 05day    286 adult female 30day    245 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    426 embryo 02-04hr    117 embryo 04-06hr    42 embryo 06-08hr    30 embryo 08-10hr    31 embryo 10-12hr    56 embryo 12-14hr    78 embryo 14-16hr    207 embryo 16-18hr    257 embryo 18-20hr    255 embryo 20-22hr    236 embryo 22-24hr    253 larva L1    255 larva L2    357 larva L3 12hr old    150 larva L3 puffstage 1-2    52 larva L3 puffstage 3-6    44 larva L3 puffstage 7-9    29 white prepupae new    45 white prepupae 12hr    71 white prepupae 24hr    87 pupae 2d postWPP    243 pupae 3d postWPP    750 pupae 4d postWPP    148 adult male 01day    76 adult male 05day    52 adult male 30day    45 adult female 01day    195 adult female 05day    286 adult female 30day    245 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    426 embryo 02-04hr    117 embryo 04-06hr    42 embryo 06-08hr    30 embryo 08-10hr    31 embryo 10-12hr    56 embryo 12-14hr    78 embryo 14-16hr    207 embryo 16-18hr    257 embryo 18-20hr    255 embryo 20-22hr    236 embryo 22-24hr    253 larva L1    255 larva L2    357 larva L3 12hr old    150 larva L3 puffstage 1-2    52 larva L3 puffstage 3-6    44 larva L3 puffstage 7-9    29 white prepupae new    45 white prepupae 12hr    71 white prepupae 24hr    87 pupae 2d postWPP    243 pupae 3d postWPP    750 pupae 4d postWPP    148 adult male 01day    76 adult male 05day    52 adult male 30day    45 adult female 01day    195 adult female 05day    286 adult female 30day    245 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0036368 expression level Developmental Stage   Expression Level embryo 00-02hr    426 embryo 02-04hr    117 embryo 04-06hr    42 embryo 06-08hr    30 embryo 08-10hr    31 embryo 10-12hr    56 embryo 12-14hr    78 embryo 14-16hr    207 embryo 16-18hr    257 embryo 18-20hr    255 embryo 20-22hr    236 embryo 22-24hr    253 larva L1    255 larva L2    357 larva L3 12hr old    150 larva L3 puffstage 1-2    52 larva L3 puffstage 3-6    44 larva L3 puffstage 7-9    29 white prepupae new    45 white prepupae 12hr    71 white prepupae 24hr    87 pupae 2d postWPP    243 pupae 3d postWPP    750 pupae 4d postWPP    148 adult male 01day    76 adult male 05day    52 adult male 30day    45 adult female 01day    195 adult female 05day    286 adult female 30day    245 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (426) embryo 02-04hr  117 embryo 04-06hr    42 embryo 06-08hr    30 embryo 08-10hr    31 embryo 10-12hr    56 embryo 12-14hr    78 embryo 14-16hr  (207) embryo 16-18hr  (257) embryo 18-20hr  (255) embryo 20-22hr  (236) embryo 22-24hr  (253) larva L1  (255) larva L2  (357) larva L3 12hr old  (150) larva L3 puffstage 1-2    52 larva L3 puffstage 3-6    44 larva L3 puffstage 7-9    29 white prepupae new    45 white prepupae 12hr    71 white prepupae 24hr    87 pupae 2d postWPP  (243) pupae 3d postWPP  (750) pupae 4d postWPP  (148) adult male 01day    76 adult male 05day    52 adult male 30day    45 adult female 01day  (195) adult female 05day  (286) adult female 30day  (245) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    426 embryo 02-04hr    117 embryo 04-06hr    42 embryo 06-08hr    30 embryo 08-10hr    31 embryo 10-12hr    56 embryo 12-14hr    78 embryo 14-16hr    207 embryo 16-18hr    257 embryo 18-20hr    255 embryo 20-22hr    236 embryo 22-24hr    253 larva L1    255 larva L2    357 larva L3 12hr old    150 larva L3 puffstage 1-2    52 larva L3 puffstage 3-6    44 larva L3 puffstage 7-9    29 white prepupae new    45 white prepupae 12hr    71 white prepupae 24hr    87 pupae 2d postWPP    243 pupae 3d postWPP    750 pupae 4d postWPP    148 adult male 01day    76 adult male 05day    52 adult male 30day    45 adult female 01day    195 adult female 05day    286 adult female 30day    245 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    426 embryo 02-04hr    117 embryo 04-06hr    42 embryo 06-08hr    30 embryo 08-10hr    31 embryo 10-12hr    56 embryo 12-14hr    78 embryo 14-16hr    207 embryo 16-18hr    257 embryo 18-20hr    255 embryo 20-22hr    236 embryo 22-24hr    253 larva L1    255 larva L2    357 larva L3 12hr old    150 larva L3 puffstage 1-2    52 larva L3 puffstage 3-6    44 larva L3 puffstage 7-9    29 white prepupae new    45 white prepupae 12hr    71 white prepupae 24hr    87 pupae 2d postWPP    243 pupae 3d postWPP    750 pupae 4d postWPP    148 adult male 01day    76 adult male 05day    52 adult male 30day    45 adult female 01day    195 adult female 05day    286 adult female 30day    245 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    426 embryo 02-04hr    117 embryo 04-06hr    42 embryo 06-08hr    30 embryo 08-10hr    31 embryo 10-12hr    56 embryo 12-14hr    78 embryo 14-16hr    207 embryo 16-18hr    257 embryo 18-20hr    255 embryo 20-22hr    236 embryo 22-24hr    253 larva L1    255 larva L2    357 larva L3 12hr old    150 larva L3 puffstage 1-2    52 larva L3 puffstage 3-6    44 larva L3 puffstage 7-9    29 white prepupae new    45 white prepupae 12hr    71 white prepupae 24hr    87 pupae 2d postWPP    243 pupae 3d postWPP    750 pupae 4d postWPP    148 adult male 01day    76 adult male 05day    52 adult male 30day    45 adult female 01day    195 adult female 05day    286 adult female 30day    245 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0036368    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0036368 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Little or no expression detected in any larval or adult organs/tissues. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Heatmap Tissue   Expression Level Larval Central Nervous System no informative data Larval Midgut no informative data Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland no informative data Larval Trachea no informative data Larval Carcass     Adult Head     Adult Eye     Adult Brain no informative data Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_19
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0036368 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG10738-RB;CG10738-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable, with Scer\GAL4pnr-MD237 CG10738GD2550 Phenotype manifest in Allele
Classical Alleles ( 2 )
For All Classical Alleles Show
Allele of CG10738 Class Mutagen Stocks Known lesion CG10738MB04068 1 -- CG10738MI02224 1 --
Alleles Carried on Transgenic Constructs ( 2 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG10738 Class Mutagen Stocks Known lesion CG10738HM05067 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG10738GD2550 in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(3L)Exel9017 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD2550} NA P{TRiP.HM05067} NA
Insertions
	Type of insertions Name Expression data insertion of enhancer trap binary system Mi{ET1}CG10738MB04068 No miscellaneous insertions Mi{MIC}CG10738MI02224 NA
Gene Ontology: Function, Process & Cellular Component ( 9 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 9 terms )
Molecular Function
CV term Evidence References
ATP binding inferred from electronic annotation with InterPro:IPR000719 (FlyBase Curators et al., 2004-) guanylate cyclase activity inferred from sequence or structural similarity (Morrison et al., 2000, Elphick, 2000.5.3) inferred from sequence or structural similarity with mouse Npr1 (FlyBase, 1992-) protein kinase activity inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR001245 (FlyBase Curators et al., 2004-) receptor activity inferred from sequence or structural similarity (Morrison et al., 2000, Elphick, 2000.5.3) inferred from sequence or structural similarity with UniProtKB:P20594 (FlyBase, 1992-)
Biological Process
CV term Evidence References
cGMP biosynthetic process inferred from electronic annotation with InterPro:IPR011645 (FlyBase Curators et al., 2004-) intracellular signal transduction inferred from electronic annotation with InterPro:IPR001054, InterPro:IPR018297 (FlyBase Curators et al., 2004-) protein phosphorylation inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR001245 (FlyBase Curators et al., 2004-) signal transduction inferred from sequence or structural similarity (Morrison et al., 2000)
Cellular Component
CV term Evidence References
plasma membrane inferred from sequence or structural similarity (Morrison et al., 2000)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG10738 allele Gene References
External Data
Linkouts	DroID - A comprehensive database of gene and protein interactions. • FBgn0036368
Orthologs
Genome-wide drosophilid orthologs	Dana\GF23467 Dere\GG15646 Dgri\GH14819 Dmoj\GI13925 Dpse\GA10532 Dsec\GM25423 Dsim\GD14452 Dvir\GJ13714 Dwil\GK17073 Dyak\GE21974
Curated drosophilid orthologs	Dpse\GA10532
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL008387-PA Aedes aegypti (mosquito) AGAP012161-PA Anopheles gambiae (mosquito) XP_623361.2 Apis mellifera (honey bee) 126532 Branchiostoma floridae (lancelet) BGIBMGA006799-PA Bombyx mori (silk worm) JA07456 Caenorhabditis japonica (nematode) CPIJ010082 Culex pipens (mosquito) 121651 Capitella spl (polychaete worm) 195897 Daphnia pulex (daphnia) 91228 Lottia gigantea (owl limpet) 40044 Nematostella vectensis (starlet anemone) XP_001600625.1 Nasonia vitripennis (wasp) ENSOANP00000002532 Ornithorynchus anatinus (platypus) PHUM000088-PA Pediculus humanus (human body louse) PP18020 Pristionchus pacificus (nematode) XP_001182583.1 Strongylocentrotus purpuratus (purple sea urchin) XP_970405.1 Tribolium castaneum (red flour beetle) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • NV15866 LH24826 FBgn0239207 FBgn0219072 FBgn0200935 FBgn0186134 FBgn0180280 JGI_V11_195897 FBgn0070589 FBgn0158342 FBgn0136679 FBgn0122295 FBgn0107890 FBgn0100461 CPIJ010082 BGIBMGA006799 ACYPI004913 GB16030 AGAP012161 AAEL008387 PB23054 PHUM100000 GLEAN_11636
Stocks & Reagents
Stocks Listed in FlyBase ( 3 )
Bloomington	28580 y1 v1; P{TRiP.HM05067}attP2 35974 y1 w*; Mi{MIC}CG10738MI02224 24564 w1118; Mi{ET1}CG10738MB04068/TM6C, Sb1
Genomic Clones ( 1 )
	BACR17E13 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 16 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones
Other clones	IP14815
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones
Other clones	Dmel_dig_003758_0707_2558 DMG4-chr3L.23.011.pred.a DMG5-chr3L.23.012.pred.a DMG7-chr3L.23.024.pred.a DMG7-chr3L.23.024.pred.a.5prime EC051502 EC051991 EC054003 EC055376 EC056448 IP14102 IP14302 IP14915 IP15015 MB6-CG10738.a
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0036368 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 39516
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
	dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology. (Kiger et al., 2003)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_140396 NM_168547 RefSeq (Proteins) • NP_648653 NP_729905 DDBJ / EMBL / GenBank • AAF49811 AAN11824 Entrez Gene - A searchable database of RefSeq genes. • 39516 UniProtKB/TrEMBL • Q8IQK2 Q9VU79
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Protein kinase, catalytic domain (IPR000719) Adenylyl cyclase class-3/4/guanylyl cyclase (IPR001054) Extracellular ligand-binding receptor (IPR001828) Protein kinase-like domain (IPR011009) Adenylyl cyclase class-3/4/guanylyl cyclase, conserved site (IPR018297) Serine-threonine/tyrosine-protein kinase (IPR001245) Haem NO binding associated (IPR011645)
Linkouts
	DroID - A comprehensive database of gene and protein interactions. • FBgn0036368 DRSC - Results from RNAi screens. • FBgn0036368 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0036368 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG10738-RB;CG10738-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0036368 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 39516 InParanoid A subset of ortholog calls from InParanoid. • AAEL008387-PA Aedes aegypti (mosquito) AGAP012161-PA Anopheles gambiae (mosquito) XP_623361.2 Apis mellifera (honey bee) 126532 Branchiostoma floridae (lancelet) BGIBMGA006799-PA Bombyx mori (silk worm) JA07456 Caenorhabditis japonica (nematode) CPIJ010082 Culex pipens (mosquito) 121651 Capitella spl (polychaete worm) 195897 Daphnia pulex (daphnia) 91228 Lottia gigantea (owl limpet) 40044 Nematostella vectensis (starlet anemone) XP_001600625.1 Nasonia vitripennis (wasp) ENSOANP00000002532 Ornithorynchus anatinus (platypus) PHUM000088-PA Pediculus humanus (human body louse) PP18020 Pristionchus pacificus (nematode) XP_001182583.1 Strongylocentrotus purpuratus (purple sea urchin) XP_970405.1 Tribolium castaneum (red flour beetle) modMine - Data generated by the modENCODE project. • FBgn0036368 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • NV15866 LH24826 FBgn0239207 FBgn0219072 FBgn0200935 FBgn0186134 FBgn0180280 JGI_V11_195897 FBgn0070589 FBgn0158342 FBgn0136679 FBgn0122295 FBgn0107890 FBgn0100461 CPIJ010082 BGIBMGA006799 ACYPI004913 GB16030 AGAP012161 AAEL008387 PB23054 PHUM100000 GLEAN_11636
Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	CG10738 (Perkins et al., 2009) GYC (Morrison et al., 2000)
Name Synonym
Secondary FlyBase IDs
References ( 14 )
Supplementary material	The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518] Kiger et al., 2003, J. Biol. 2(4): Additional data file 1: The gene identity and primer sequences for dsRNAs used in the RNAi screens. [FBrf0174231] Morrison et al., 2000, J. Cell Biol. 150(2): Table S1. Drosophila protein kinases and phosphatases. [FBrf0132098]
Personal communication to FlyBase	Bellen, 2011.5.24, set932.xml set932.xml [FBrf0213718] Perkins et al., 2009, Update to TRiP stock collection. Update to TRiP stock collection. [FBrf0208864] BDGP TI submission, 2007.10.9, batch761.xml batch761.xml [FBrf0200260] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] FlyBase Curators et al., 2004-, Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. [FBrf0174215] Ryder, 2004.4.26, Exelixis CG deletion data. Exelixis CG deletion data. [FBrf0184335] Elphick, 2000.5.3, FlyBase error report for CG10738 on Wed May 3 09:36:25 2000. FlyBase error report for CG10738 on Wed May 3 09:36:25 2000. [FBrf0129019]
FlyBase analysis	FlyBase, 1992-, FlyBase curation FlyBase curation. [FBrf0105495]
Automatic genome annotation	FamiliarityBreedsContempt, 1999.11, [Annotations performed at the Celera Jamboreee.] [Annotations performed at the Celera Jamboreee.] [FBrf0126705]
Curated genome annotation	Zhu, 1999.11, [Annotations performed at the Celera Jamboreee.] [Annotations performed at the Celera Jamboreee.] [FBrf0126704]