FB2025_01 , released February 20, 2025
Gene: Dmel\Cep135
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General Information
Symbol
Dmel\Cep135
Species
D. melanogaster
Name
Centrosomal protein 135kDa
Annotation Symbol
CG17081
Feature Type
protein_coding_gene
FlyBase ID
FBgn0036480
Gene Model Status
Current
Stock Availability
10 publicly available
Gene Summary
Centrosomal protein 135kDa (Cep135) encodes a microtubule binding protein important for centriole elongation and stability. It promotes centrosome asymmetry and spindle orientation in neuroblasts and it is required for male fertility. [Date last reviewed: 2019-03-07] (FlyBase Gene Snapshot)
All Summaries
Also Known As

Bld10, DCep135, dbld10

Key Links
Genomic Location
Cytogenetic map
71B5-71B5
Sequence location
Recombination map
3-42
RefSeq locus
NT_037436 REGION:15116737..15128029
Sequence
Get Decorated FASTA
Genomic Maps
Other Genome Views
The following external sites may use different assemblies or annotations than FlyBase.
NCBI
UCSC
Ensembl
PopFly
Function
Gene Ontology (GO) Annotations (14 terms)
Molecular Function (1 term)
Terms Based on Experimental Evidence (1 term)
CV Term
Evidence
References
enables microtubule binding
inferred from direct assay
(Carvalho-Santos et al., 2012)
Terms Based on Predictions or Assertions (0 terms)
Biological Process (9 terms)
Terms Based on Experimental Evidence (9 terms)
CV Term
Evidence
References
involved_in asymmetric neuroblast division
inferred from mutant phenotype
(Singh et al., 2014)
involved_in centriole replication
inferred from mutant phenotype
(Dobbelaere et al., 2008)
involved_in centrosome cycle
inferred from mutant phenotype
(Blachon et al., 2009)
involved_in ciliary basal body organization
inferred from mutant phenotype
(Jana et al., 2018)
inferred from mutant phenotype
(Mottier-Pavie and Megraw, 2009)
involved_in mitotic centrosome separation
inferred from mutant phenotype
(Singh et al., 2014)
involved_in motile cilium assembly
inferred from mutant phenotype
(Dobbelaere et al., 2023)
involved_in negative regulation of microtubule depolymerization
inferred from mutant phenotype
(Carvalho-Santos et al., 2012)
involved_in non-motile cilium assembly
inferred from mutant phenotype
(Dobbelaere et al., 2023)
involved_in sperm axoneme assembly
inferred from mutant phenotype
(Carvalho-Santos et al., 2012, Carvalho-Santos et al., 2010, Mottier-Pavie and Megraw, 2009)
Terms Based on Predictions or Assertions (0 terms)
Cellular Component (4 terms)
Terms Based on Experimental Evidence (4 terms)
CV Term
Evidence
References
located_in centriole
inferred from direct assay
(Roque et al., 2012, Blachon et al., 2009, Mottier-Pavie and Megraw, 2009, Dobbelaere et al., 2008)
located_in centrosome
inferred from direct assay
(Carvalho-Santos et al., 2010, Mottier-Pavie and Megraw, 2009)
located_in ciliary basal body
inferred from direct assay
(Dobbelaere et al., 2023, Mottier-Pavie and Megraw, 2009)
inferred from direct assay
(Jana et al., 2018)
located_in ciliary transition zone
inferred from direct assay
(Jana et al., 2018)
Terms Based on Predictions or Assertions (0 terms)
Gene Group (FlyBase)
Protein Family (UniProt)
-
Protein Signatures (InterPro)
Summaries
Gene Snapshot
Centrosomal protein 135kDa (Cep135) encodes a microtubule binding protein important for centriole elongation and stability. It promotes centrosome asymmetry and spindle orientation in neuroblasts and it is required for male fertility. [Date last reviewed: 2019-03-07]
Summary (Interactive Fly)

scaffolding protein - assembly of microtubule based structures, centriole and flagella biogenesis

Gene Model and Products
Number of Transcripts
3
Number of Unique Polypeptides
3

Please see the JBrowse view of Dmel\Cep135 for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)
Isoform displayed:
Pfam protein domains
InterPro name
classification
start
end
Protein Domains (via SMART)
Isoform displayed:
SMART protein domains
InterPro name
classification
start
end
Structure
Protein 3D structure   (Predicted by AlphaFold)   (AlphaFold entry M9MSL4)

If you don't see a structure in the viewer, refresh your browser.
Model Confidence:
  • Very high (pLDDT > 90)
  • Confident (90 > pLDDT > 70)
  • Low (70 > pLDDT > 50)
  • Very low (pLDDT < 50)

AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.

Experimentally Determined Structures
Crossreferences
Comments on Gene Model

Low-frequency RNA-Seq exon junction(s) not annotated.

Gene model reviewed during 5.46

Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Assoc. CDS (aa)
Cep135-RA
FBtr0075638
NM_140492
3427
1059
Cep135-RB
FBtr0303375
NM_001202179
3445
1065
Cep135-RC
FBtr0333853
NM_001274940
3552
960
Additional Transcript Data and Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kDa)
Length (aa)
Theoretical pI
UniProt
RefSeq ID
GenBank
Cep135-PA
FBpp0075391
123.1
1059
6.33
Q960T6
NP_648749
AAF49663
Cep135-PB
FBpp0292437
123.8
1065
6.46
M9MSL4
NP_001189108
ADV37544
Cep135-PC
FBpp0305986
110.9
960
6.37
M9PCK8
NP_001261869
AGB94562
Polypeptides with Identical Sequences

None of the polypeptides share 100% sequence identity.

Additional Polypeptide Data and Comments
Reported size (kDa)
Comments
External Data
Crossreferences
InterPro - A database of protein families, domains and functional sites
Linkouts
Sequences Consistent with the Gene Model
Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Cep135 using the Feature Mapper tool.

External Data
Crossreferences
Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
Linkouts
Expression Data
Testis-specificity index

The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).

1.17

Transcript Expression
Polypeptide Expression
mass spectroscopy
Stage
Tissue/Position (including subcellular localization)
Reference
day 5 of adulthood & male -- day 7 of adulthood & male
spermatozoon
(Wasbrough et al., 2010)
Additional Descriptive Data
Marker for
 
Subcellular Localization
CV Term
Evidence
References
located_in centriole
inferred from direct assay
(Roque et al., 2012, Blachon et al., 2009, Mottier-Pavie and Megraw, 2009, Dobbelaere et al., 2008)
located_in centrosome
inferred from direct assay
(Carvalho-Santos et al., 2010, Mottier-Pavie and Megraw, 2009)
located_in ciliary basal body
inferred from direct assay
(Dobbelaere et al., 2023, Mottier-Pavie and Megraw, 2009)
inferred from direct assay
(Jana et al., 2018)
located_in ciliary transition zone
inferred from direct assay
(Jana et al., 2018)
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools

JBrowse - Visual display of RNA-Seq signals

View Dmel\Cep135 in JBrowse
RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region
Bulk Downloads
RNA-Seq RPKM values for all genes
Reference
See Gelbart and Emmert, 2013 for analysis details and data files for all genes.
Developmental Proteome: Life Cycle
Developmental Proteome: Embryogenesis
External Data and Images
Linkouts
BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species
EMBL-EBI Single Cell Expression Atlas - Single cell expression across species
FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data
Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
Flygut - An atlas of the Drosophila adult midgut
Images
FlyBase Wiki
Image Based Resources
Alleles, Insertions, Transgenic Constructs, and Aberrations
Classical and Insertion Alleles ( 7 )
For All Classical and Insertion Alleles Show
 
Other relevant insertions
Transgenic Constructs ( 16 )
For All Alleles Carried on Transgenic Constructs Show
Transgenic constructs containing/affecting coding region of Cep135
Transgenic constructs containing regulatory region of Cep135
Aberrations (Deficiencies and Duplications) ( 2 )
Inferred from experimentation ( 2 )
Gene disrupted in
Df(3L)Exel6262
(Ryder, 2004.4.26)
Gene partially disrupted in
Df(3L)Cep135ΔN
(Singh et al., 2014)
Inferred from location ( 7 )
Variants
Variant Molecular Consequences
Alleles Representing Disease-Implicated Variants
Phenotypes
For more details about a specific phenotype click on the relevant allele symbol.
Lethality
Allele
viable
viable, with Dcr-2UAS.cDa, Scer\GAL4elav.PLu
viable, with Scer\GAL4Mef2.PR
viable, with Scer\GAL4pnr-MD237
viable, with Scer\GAL4tin.CΔ4
viable, with Scer\GAL4αTub84B.PL
viable (with Df(3L)Brd15)
Sterility
Allele
female fertile
female fertile (with Cep135c04199)
female fertile (with Cep135f01951)
fertile, with Scer\GAL4αTub84B.PL
male sterile
male sterile (with Cep135c04199)
male sterile (with Cep135f01951)
male sterile (with Df(3L)Brd15)
male sterile (with Df(3L)ED218)
male sterile | recessive
Other Phenotypes
Allele
abnormal meiotic cell cycle | male (with Df(3L)Brd15)
visible, with Scer\GAL4pnr-MD237
Phenotype manifest in
Allele
centriole (with Df(3L)Brd15)
centriole (with Df(3L)ED218)
centriole | progressive
chaeta, with Scer\GAL4pnr-MD237
interphase microtubule organizing center (with Df(3L)Brd15)
mitotic spindle (with Df(3L)Brd15)
neuroblast (with Df(3L)Brd15)
primary spermatocyte
spermatid axoneme
spermatid axoneme (with Df(3L)Brd15)
spermatozoon
spermatozoon (with Cep135c04199)
spermatozoon (with Cep135f01951)
Orthologs
Downloads
Download All DIOPT Orthologs
Human Orthologs (via DIOPT v9.1)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
Domainoid
eggNOG
Hieranoid
Homologene
Inparanoid
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
SonicParanoid
Alignment
Complementation?
Transgene?
Homo sapiens (Human) (4)
Hsap\CEP135
11 of 14
Yes
Yes
2  
Hsap\TSGA10
8 of 14
No
Yes
2  
Hsap\LAMA1
1 of 14
No
No
Hsap\LAMA3
1 of 14
No
No
Model Organism Orthologs (via DIOPT v9.1)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
Domainoid
eggNOG
Hieranoid
Homologene
Inparanoid
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
SonicParanoid
Alignment
Complementation?
Transgene?
Rattus norvegicus (Norway rat) (2)
Rnor\Cep135
11 of 14
Yes
Yes
Rnor\Tsga10
8 of 14
No
Yes
Mus musculus (laboratory mouse) (4)
Mmus\Cep135
11 of 14
Yes
Yes
Mmus\Tsga10
7 of 14
No
Yes
Mmus\Lama2
1 of 14
No
No
Mmus\Lama3
1 of 14
No
No
Xenopus tropicalis (Western clawed frog) (2)
Xtro\tsga10
7 of 13
Yes
Yes
Xtro\cep135
6 of 13
No
Yes
Danio rerio (Zebrafish) (3)
Drer\cep135
11 of 14
Yes
Yes
Drer\tsga10
8 of 14
No
Yes
Drer\lama5
1 of 14
No
No
Caenorhabditis elegans (Nematode, roundworm) (2)
Cele\epi-1
1 of 14
Yes
No
Cele\tag-278
1 of 14
Yes
Yes
Anopheles gambiae (African malaria mosquito) (3)
Agam\AgaP_AGAP010985
11 of 12
Yes
Yes
Agam\AgaP_AGAP004993
1 of 12
No
No
Agam\AgaP_AGAP010286
1 of 12
No
No
Arabidopsis thaliana (thale-cress) (1)
Atha\CIP1
2 of 13
Yes
Yes
Saccharomyces cerevisiae (Brewer's yeast) (0)
Schizosaccharomyces pombe (Fission yeast) (0)
Escherichia coli (enterobacterium) (0)
Other Organism Orthologs (via OrthoDB)
Data provided directly from OrthoDB:Cep135. Refer to their site for version information.
Paralogs
Downloads
Download All DIOPT Paralogs
Paralogs (via DIOPT v9.1)
Gene Symbol
Score
Source
Compara
Domainoid
eggNOG
Homologene
Inparanoid
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
SonicParanoid
Alignment
Drosophila melanogaster (Fruit fly) (2)
LanA
1 of 13
Root
1 of 13
Human Disease Associations
FlyBase Human Disease Model Reports
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Evidence
    References
    Potential Models Based on Orthology ( 2 )
    Modifiers Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Interaction
    References
    Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)
    Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.
    Homo sapiens (Human)
    Gene name
    Score
    OMIM
    OMIM Phenotype
    DO term
    Complementation?
    Transgene?
    CEP135; centrosomal protein 135
    11 of 14
    611423
     
    TSGA10; testis specific 10
    8 of 14
    607166
     
    Functional Complementation Data
    Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.
    Interactions
    Summary of Physical Interactions
    esyN Network Diagram
    Show neighbor-neighbor interactions:
    Show/hide secondary interactors 
    (data from AllianceMine provided by esyN)
    Select Layout:
    Legend:
    Protein
    RNA
    Selected Interactor(s)
    Other Interaction Browsers
    View in FlyBase Interactions Browser   View in MIST tool (external link)
    Please see the Physical Interaction reports below for full details
    protein-protein
    Physical Interaction
    Assay
    References
    Cep135
    anti tag coimmunoprecipitation, anti tag western blot, two hybrid
    (Galletta et al., 2016)
    Cep135 - Cp110
    two hybrid
    (Galletta et al., 2016)
    Cep135 - Nek2
    two hybrid
    (Galletta et al., 2016)
    Cep135 - SAK
    two hybrid, pull down, autoradiography, protein kinase assay, Identification by mass spectrometry, molecular weight estimation by staining, anti tag coimmunoprecipitation, anti tag western blot
    (Ábrahám et al., 2023, Galletta et al., 2016)
    Cep135 - Sas-4
    pull down, western blot, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, anti tag western blot, two hybrid
    (Galletta et al., 2016, Zheng et al., 2014)
    Cep135 - ana1
    anti tag coimmunoprecipitation, anti tag western blot, pull down, autoradiography, two hybrid, cosedimentation
    (Fu et al., 2016, Galletta et al., 2016)
    Cep135 - ana2
    anti tag coimmunoprecipitation, anti tag western blot, pull down, autoradiography, two hybrid
    (McLamarrah et al., 2020, Galletta et al., 2016, Dzhindzhev et al., 2014)
    Cep135 - asl
    two hybrid, cosedimentation, anti tag western blot
    (Fu et al., 2016, Galletta et al., 2016)
    Cep135 - cnn
    two hybrid
    (Galletta et al., 2016)
    Summary of Genetic Interactions
    esyN Network Diagram
    Other Interaction Browsers
    Starting gene(s)
    Interaction type
    Interacting gene(s)
    Reference
    Starting gene(s)
    Interaction type
    Interacting gene(s)
    Reference
    External Data
    Linkouts
    BioGRID - A database of protein and genetic interactions.
    DroID - A comprehensive database of gene and protein interactions.
    MIST (protein-protein) - An integrated Molecular Interaction Database
    Pathways
    Signaling Pathways (FlyBase)
    Metabolic Pathways
    FlyBase
    External Links
    External Data
    Linkouts
    Class of Gene
    Genomic Location and Detailed Mapping Data
    Chromosome (arm)
    3L
    Recombination map
    3-42
    Cytogenetic map
    71B5-71B5
    Sequence location
    FlyBase Computed Cytological Location
    Cytogenetic map
    Evidence for location
    71B5-71B5
    Limits computationally determined from genome sequence between P{lacW}cp309s2172&P{lacW}l(3)j2A2j2A2 and P{EP}Tfb2EP572
    Experimentally Determined Cytological Location
    Cytogenetic map
    Notes
    References
    Experimentally Determined Recombination Data
    Location

    3-42

    (FlyBase, 2016)

    3-36.6

    (Comeron et al., 2012)
    Left of (cM)
    Right of (cM)
    Notes
    Stocks and Reagents
    Stocks (10)
    Genomic Clones (22)
    cDNA Clones (21)
     

    Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.

    cDNA clones, fully sequenced
    BDGP DGC clones
    Other clones
      Drosophila Genomics Resource Center cDNA clones

      For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

      cDNA Clones, End Sequenced (ESTs)
      BDGP DGC clones
      Other clones
      RNAi and Array Information
      Linkouts
      DRSC - Results frm RNAi screens
      Antibody Information
      Laboratory Generated Antibodies
       

      polyclonal

      (Tian et al., 2021, Fu et al., 2016, Carvalho-Santos et al., 2012, Roque et al., 2012, Mottier-Pavie and Megraw, 2009)
      Commercially Available Antibodies
       
      Cell Line Information
      Publicly Available Cell Lines
       
        Other Stable Cell Lines
         

        • New stable cell line derived from S2-ThermoFischer : Centriolar proteins were tagged with GFP at either the N- or C- terminus and used to create stable S2 cell lines. S2 cell lines constitutively expressing the following constructs were created: asl-GFP, Sas-6-GFP, ana1-GFP, GFP-ana1, Cep135-GFP, ana3-GFP, Rcd4-GFP, ana2-GFP, GFP-asl.

          (Tian et al., 2021)
        Other Comments

        Cep135 is required for the early steps of central microtubule pair formation in the flagellar axoneme during spermatogenesis.

        (Carvalho-Santos et al., 2012)

        Cep135 is not essential for cartwheel assembly or for establishing the ninefold symmetry of centrioles; rather, it appears to stabilize the connection betwen inner and outer centriole components.

        (Roque et al., 2012)

        Cep135 regulates centriole, basal body and motile cilium assembly.

        (Mottier-Pavie and Megraw, 2009)

        Cep135 is involved in centriole duplication and is required for efficient recruitment of pericentriolar material.

        (Dobbelaere et al., 2008)
        Relationship to Other Genes
        Source for database merge of
        Additional comments
        Nomenclature History
        Source for database identify of

        Source for identity of: Cep135 CG17081

        (Dobbelaere et al., 2008)
        Nomenclature comments
        Etymology
        Synonyms and Secondary IDs (15)
        Reported As
        Symbol Synonym
        BLD10
        (Jana et al., 2018, Pimenta-Marques et al., 2016)
        Bld-10
        (Zheng et al., 2014)
        Bld10
        (Pimenta-Marques et al., 2024, Ito et al., 2019, Lattao et al., 2017, Jana et al., 2016, Khire et al., 2016, Saurya et al., 2016, Homem et al., 2015, Khire et al., 2015, Lerit et al., 2015, Dzhindzhev et al., 2014, Carvalho-Santos et al., 2012, Fabian and Brill, 2012, Nguyen et al., 2011, Dzhindzhev et al., 2010)
        Bld10p
        (Blachon et al., 2009)
        CEP135
        (Naveed et al., 2018, Carvalho-Santos et al., 2010)
        CG17081
        (Dobbelaere et al., 2023, Balmer et al., 2015, Chen et al., 2012, Japanese National Institute of Genetics, 2012.5.21, Zhang et al., 2010, Mottier-Pavie and Megraw, 2009, Perkins et al., 2009, Dobbelaere et al., 2008)
        Cep135
        (Ábrahám et al., 2023, Dobbelaere et al., 2023, Blümel et al., 2022, Marcogliese et al., 2022, Alvarez-Rodrigo et al., 2021, Pizzo et al., 2021, Szikora et al., 2021, Tian et al., 2021, Marthiens and Basto, 2020, McLamarrah et al., 2020, Robinson et al., 2020, Gene Disruption Project members, 2018-, Tillery et al., 2018, Lattao et al., 2017, Galletta et al., 2016, Gene Disruption Project members, 2016-, Saurya et al., 2016, Fu et al., 2015, Gene Disruption Project members, 2015-, Homem et al., 2015, Franz et al., 2013, Roque et al., 2012, Wasbrough et al., 2010, Wasbrough et al., 2010, Blachon et al., 2008)
        Cep135/bld10
        (Debec et al., 2020)
        DBld10
        (Gogendeau and Basto, 2010)
        DCep135
        (Stevens et al., 2010, Dobbelaere et al., 2008)
        DCep135/Bld10
        (Stevens et al., 2010)
        DmBLD10
        (Carvalho-Santos et al., 2010)
        bld10
        (Zheng et al., 2020, Fu et al., 2016, Zheng et al., 2016, Chen et al., 2015, Singh et al., 2014, Fabian and Brill, 2012, Blachon et al., 2009, Mottier-Pavie and Megraw, 2009)
        dbld10
        (Blachon et al., 2009, Blachon et al., 2008)
        Name Synonyms
        CG17081
        Centrosomal protein 135kDa
        Cep135
        (Wasbrough et al., 2010)
        Secondary FlyBase IDs
          Datasets (0)
          Study focus (0)
          Experimental Role
          Project
          Project Type
          Title
          Study result (0)
          Result
          Result Type
          Title
          External Crossreferences and Linkouts ( 40 )
          Sequence Crossreferences
          NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.
          GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
          GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.
          RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.
          UniProt/GCRP - The gene-centric reference proteome (GCRP) provides a 1:1 mapping between genes and UniProt accessions in which a single 'canonical' isoform represents the product(s) of each protein-coding gene.
          UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information
          Other crossreferences
          AlphaFold DB - AlphaFold provides open access to protein structure predictions for the human proteome and other key proteins of interest, to accelerate scientific research.
          BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
          DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species
          EMBL-EBI Single Cell Expression Atlas - Single cell expression across species
          FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data
          FlyMine - An integrated database for Drosophila genomics
          InterPro - A database of protein families, domains and functional sites
          KEGG Genes - Molecular building blocks of life in the genomic space.
          MARRVEL_MODEL - MARRVEL (model organism gene)
          Linkouts
          BioGRID - A database of protein and genetic interactions.
          Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones
          DroID - A comprehensive database of gene and protein interactions.
          DRSC - Results frm RNAi screens
          Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
          FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
          FlyCyc Genes - Genes from a BioCyc PGDB for Dmel
          Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
          Flygut - An atlas of the Drosophila adult midgut
          iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)
          Interactive Fly - A cyberspace guide to Drosophila development and metazoan evolution
          MIST (protein-protein) - An integrated Molecular Interaction Database
          References (88)