FlyBase Gene Report: Dmel\Cep135

General Information

Symbol

Dmel\Cep135

Species

D. melanogaster

Name

Centrosomal protein 135kDa

Annotation Symbol

CG17081

Feature Type

protein_coding_gene

FlyBase ID

FBgn0036480

Gene Model Status

Stock Availability

9 publicly available

Gene Snapshot

Centrosomal protein 135kDa (Cep135) encodes a microtubule binding protein important for centriole elongation and stability. It promotes centrosome asymmetry and spindle orientation in neuroblasts and it is required for male fertility. [Date last reviewed: 2019-03-07]

Other Summaries

Alliance
Auto summary
Interactive Fly

Also Known As

Bld10, dbld10, DCep135

Key Links

Genomic Location

Cytogenetic map

Sequence location

3L:15,116,737..15,128,029 [+]

Recombination map

3-42

RefSeq locus

NT_037436 REGION:15116737..15128029

Sequence

Get Decorated FASTA

Genomic Maps

JBrowse GBrowse

Other Genome Views

The following external sites may use different assemblies or annotations than FlyBase.

Function

GO Summary Ribbons

Gene Ontology (GO) Annotations (12 terms)

Molecular Function (1 term)

Terms Based on Experimental Evidence (1 term)

CV Term

Evidence

References

enables microtubule binding

inferred from direct assay

(Carvalho-Santos et al., 2012)

Terms Based on Predictions or Assertions (0 terms)

Biological Process (7 terms)

Terms Based on Experimental Evidence (7 terms)

CV Term

Evidence

References

involved_in asymmetric neuroblast division

inferred from mutant phenotype

(Singh et al., 2014)

involved_in centriole replication

inferred from mutant phenotype

(Dobbelaere et al., 2008)

involved_in centrosome cycle

inferred from mutant phenotype

(Blachon et al., 2009)

involved_in ciliary basal body organization

inferred from mutant phenotype

(Mottier-Pavie and Megraw, 2009)

inferred from mutant phenotype

(assigned by UniProt )

(Jana et al., 2018)

involved_in mitotic centrosome separation

inferred from mutant phenotype

(Singh et al., 2014)

involved_in negative regulation of microtubule depolymerization

inferred from mutant phenotype

(Carvalho-Santos et al., 2012)

involved_in sperm axoneme assembly

inferred from mutant phenotype

(Carvalho-Santos et al., 2012, Carvalho-Santos et al., 2010, Mottier-Pavie and Megraw, 2009)

Terms Based on Predictions or Assertions (0 terms)

Cellular Component (4 terms)

Terms Based on Experimental Evidence (4 terms)

CV Term

Evidence

References

located_in centriole

inferred from direct assay

(Roque et al., 2012, Blachon et al., 2009, Mottier-Pavie and Megraw, 2009, Dobbelaere et al., 2008)

located_in centrosome

inferred from direct assay

(Carvalho-Santos et al., 2010, Mottier-Pavie and Megraw, 2009)

located_in ciliary basal body

inferred from direct assay

(Mottier-Pavie and Megraw, 2009)

inferred from direct assay

(assigned by UniProt )

(Jana et al., 2018)

located_in ciliary transition zone

inferred from direct assay

(assigned by UniProt )

(Jana et al., 2018)

Terms Based on Predictions or Assertions (0 terms)

Gene Group (FlyBase)

Protein Family (UniProt)

-

Protein Signatures (InterPro)

-

Summaries

Summary (Interactive Fly)

Interactive Fly

Gene Model and Products

Number of Transcripts

3

Number of Unique Polypeptides

3

Please see the JBrowse view of Dmel\Cep135 for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)

Isoform displayed:

Pfam protein domains

InterPro name

classification

start

end

Protein Domains (via SMART)

Isoform displayed:

SMART protein domains

InterPro name

classification

start

end

Comments on Gene Model

Low-frequency RNA-Seq exon junction(s) not annotated.

Gene model reviewed during 5.46

Sequence Ontology: Class of Gene

protein_coding_gene

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Assoc. CDS (aa)

FBtr0075638

3427

1059

FBtr0303375

3445

1065

FBtr0333853

3552

960

Additional Transcript Data and Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

RefSeq ID

GenBank

FBpp0075391

123.1

1059

6.33

FBpp0292437

123.8

1065

6.46

FBpp0305986

110.9

960

6.37

Polypeptides with Identical Sequences

None of the polypeptides share 100% sequence identity.

Additional Polypeptide Data and Comments

Reported size (kDa)

Comments

External Data

Crossreferences

Linkouts

Sequences Consistent with the Gene Model

Nucleotide / Polypeptide Records

Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Cep135 using the Feature Mapper tool.

External Data

Crossreferences

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

Cep135_1

Linkouts

Expression Data

Expression Summary Ribbons

Colored tiles in ribbon indicate that expression data has been curated by FlyBase for that anatomical location. Colorless tiles indicate that there is no curated data for that location.

For complete stage-specific expression data, view the modENCODE Development RNA-Seq section under High-Throughput Expression below.

Transcript Expression

in situ

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 1 -- 3

Comment: maternally deposited

(Fisher et al., 2012)

embryonic stage 4 -- 6

(Fisher et al., 2012)

embryonic stage 7 -- 8

organism | ubiquitous

(Fisher et al., 2012)

embryonic stage 9 -- 10

organism | ubiquitous

(Fisher et al., 2012)

embryonic stage 11 -- 12

organism | ubiquitous

(Fisher et al., 2012)

embryonic stage 13 -- 16

embryonic brain

(Fisher et al., 2012)

ventral nerve cord

(Fisher et al., 2012)

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

mass spectroscopy

Stage

Tissue/Position (including subcellular localization)

Reference

day 5 of adulthood & male -- day 7 of adulthood & male

(Wasbrough et al., 2010)

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Evidence

References

located_in centriole

inferred from direct assay

(Roque et al., 2012, Blachon et al., 2009, Mottier-Pavie and Megraw, 2009, Dobbelaere et al., 2008)

located_in centrosome

inferred from direct assay

(Carvalho-Santos et al., 2010, Mottier-Pavie and Megraw, 2009)

located_in ciliary basal body

inferred from direct assay

(Mottier-Pavie and Megraw, 2009)

inferred from direct assay

(assigned by UniProt )

(Jana et al., 2018)

located_in ciliary transition zone

inferred from direct assay

(assigned by UniProt )

(Jana et al., 2018)

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

GBrowse - Visual display of RNA-Seq signals

View Dmel\Cep135 in GBrowse 2

RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region

View exonic expression by developmental stage for Dmel\Cep135

View exonic expression by tissue for Dmel\Cep135

Bulk Downloads

RNA-Seq RPKM values for all genes

Reference

See Gelbart and Emmert, 2013 for analysis details and data files for all genes.

Developmental Proteome: Life Cycle

Developmental Proteome: Embryogenesis

External Data and Images

Linkouts

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0036480

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

FBgn0036480

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

CG17081-RA

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG17081

Flygut - An atlas of the Drosophila adult midgut

FBgn0036480

Images

Image Based Resources

Alleles, Insertions, and Transgenic Constructs

Classical and Insertion Alleles ( 6 )

For All Classical and Insertion Alleles Show

Other relevant insertions

Transgenic Constructs ( 11 )

For All Alleles Carried on Transgenic Constructs Show

Transgenic constructs containing/affecting coding region of Cep135

Transgenic constructs containing regulatory region of Cep135

Deletions and Duplications ( 2 )

Disrupted in

(Ryder, 2004.4.26)

Partially disrupted in

Df(3L)Cep135^ΔN

(Singh et al., 2014)

Phenotypes

For more details about a specific phenotype click on the relevant allele symbol.

Lethality

Allele

Cep135^c04199

viable, with Dcr-2^UAS.cDa, Scer\GAL4^elav.PLu

Cep135^GD6121

viable, with Scer\GAL4^Mef2.PR

Cep135^GD6121

viable, with Scer\GAL4^pnr-MD237

Cep135^GD6121

viable, with Scer\GAL4^tin.CΔ4

Cep135^GD6121

viable, with Scer\GAL4^αTub84B.PL

Cep135^UASp.EGFP

viable (with Df(3L)Brd15)

Cep135^c04199

Sterility

Allele

female fertile (with Cep135^c04199)

Cep135^f01951

female fertile (with Cep135^f01951)

Cep135^c04199

fertile, with Scer\GAL4^αTub84B.PL

Cep135^UASp.EGFP

Cep135^c04199

male sterile (with Cep135^c04199)

Cep135^f01951

male sterile (with Cep135^f01951)

Cep135^c04199

male sterile (with Df(3L)Brd15)

Cep135^c04199

male sterile (with Df(3L)ED218)

Cep135^c04199

male sterile | recessive

Other Phenotypes

Allele

meiotic cell cycle defective | male (with Df(3L)Brd15)

Cep135^c04199

visible, with Scer\GAL4^pnr-MD237

Cep135^GD6121

Phenotype manifest in

Allele

centriole (with Df(3L)Brd15)

Cep135^c04199

centriole (with Df(3L)ED218)

Cep135^c04199

centriole | progressive

Cep135^c04199

chaeta, with Scer\GAL4^pnr-MD237

Cep135^GD6121

interphase microtubule organizing center (with Df(3L)Brd15)

Cep135^c04199

mitotic spindle (with Df(3L)Brd15)

Cep135^c04199

neuroblast (with Df(3L)Brd15)

Cep135^c04199

primary spermatocyte

Cep135^c04199

spermatid axoneme

Cep135^c04199

spermatid axoneme (with Df(3L)Brd15)

Cep135^c04199

spermatozoon (with Cep135^c04199)

Cep135^f01951

spermatozoon (with Cep135^f01951)

Cep135^c04199

Orthologs

Downloads

Download All DIOPT Orthologs

Download All OrthoDB Orthologs

Human Orthologs (via DIOPT v8.0)

Homo sapiens (Human) (2)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

12 of 15

Yes

Yes

1

7 of 15

No

Yes

2

Model Organism Orthologs (via DIOPT v8.0)

Mus musculus (laboratory mouse) (2)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

12 of 15

Yes

Yes

6 of 15

No

Yes

Rattus norvegicus (Norway rat) (2)

11 of 13

Yes

Yes

6 of 13

No

Yes

Xenopus tropicalis (Western clawed frog) (2)

7 of 12

Yes

Yes

2 of 12

No

Yes

Danio rerio (Zebrafish) (2)

11 of 15

Yes

Yes

6 of 15

No

Yes

Caenorhabditis elegans (Nematode, roundworm) (1)

1 of 15

Yes

Yes

Arabidopsis thaliana (thale-cress) (5)

1 of 9

Yes

No

1 of 9

Yes

Yes

1 of 9

Yes

Yes

1 of 9

Yes

Yes

1 of 9

Yes

Yes

Saccharomyces cerevisiae (Brewer's yeast) (0)

No records found.

Schizosaccharomyces pombe (Fission yeast) (0)

No records found.

Ortholog(s) in Drosophila Species (via OrthoDB v9.1) ( EOG0919031U )

Organism

Common Name

Gene

AAA Syntenic Ortholog

Multiple Dmel Genes in this Orthologous Group

Drosophila suzukii

Spotted wing Drosophila

Dsuz\DS10_00013333

Drosophila simulans

Drosophila sechellia

Drosophila erecta

Drosophila yakuba

Drosophila ananassae

Drosophila pseudoobscura pseudoobscura

Drosophila persimilis

Drosophila willistoni

Drosophila virilis

Drosophila mojavensis

Drosophila grimshawi

Orthologs in non-Drosophila Dipterans (via OrthoDB v9.1) ( EOG091501OU )

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Musca domestica

House fly

Glossina morsitans

Tsetse fly

Gmor\GMOY006006

Mayetiola destructor

Hessian fly

Mdes\Mdes001133

Aedes aegypti

Yellow fever mosquito

Aaeg\AAEL006340

Anopheles darlingi

American malaria mosquito

Adar\ADAC008011

Anopheles gambiae

Malaria mosquito

Agam\AGAP010985

Culex quinquefasciatus

Southern house mosquito

Cqui\CPIJ011004

Orthologs in non-Dipteran Insects (via OrthoDB v9.1) ( EOG090W023P )

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Bombyx mori

Silkmoth

Bmor\BGIBMGA011821

Danaus plexippus

Monarch butterfly

Dple\DPOGS213539-PA

Heliconius melpomene

Postman butterfly

Hmel\HMEL005478

Apis florea

Little honeybee

Aflo\2590073700

Apis mellifera

Western honey bee

Bombus impatiens

Common eastern bumble bee

Bombus terrestris

Buff-tailed bumblebee

Linepithema humile

Argentine ant

Megachile rotundata

Alfalfa leafcutting bee

Mrot\MROTU:001301

Nasonia vitripennis

Parasitic wasp

Nvit\Nasvi2EG007287

Dendroctonus ponderosae

Mountain pine beetle

Dendroctonus ponderosae

Mountain pine beetle

Tribolium castaneum

Red flour beetle

Pediculus humanus

Human body louse

Phum\PHUM055770

Rhodnius prolixus

Kissing bug

Rpro\RPRC000927

Acyrthosiphon pisum

Pea aphid

Apim\ACYPI004861

Zootermopsis nevadensis

Nevada dampwood termite

Znev\Znev_11015

Orthologs in non-Insect Arthropods (via OrthoDB v9.1) ( EOG090X01FC )

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Strigamia maritima

European centipede

Smar\SMAR011215

Daphnia pulex

Water flea

Dpux\DAPPUDRAFT_307484

Orthologs in non-Arthropod Metazoa (via OrthoDB v9.1) ( None identified )

No non-Arthropod Metazoa orthologies identified

Paralogs

Downloads

Download All DIOPT Paralogs

Paralogs (via DIOPT v8.0)

Drosophila melanogaster (Fruit fly) (1)

Gene Symbol

Score

Source

Alignment

1 of 10

Human Disease Associations

FlyBase Human Disease Model Reports

Disease Model Summary Ribbon

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Allele

Disease

Evidence

References

Potential Models Based on Orthology ( 2 )

Human Ortholog

Disease

Evidence

References

CEP135; centrosomal protein 135

model of primary autosomal recessive microcephaly 8

IEA

(FlyBase, 2019-)

TSGA10; testis specific 10

model of spermatogenic failure 26

IEA

(FlyBase, 2019-)

Modifiers Based on Experimental Evidence ( 0 )

Allele

Disease

Interaction

References

Disease Associations of Human Orthologs (via DIOPT v8.0 and OMIM)

Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.

Homo sapiens (Human)

Gene name

Score

OMIM

OMIM Phenotype

DO term

Complementation?

Transgene?

CEP135; centrosomal protein 135

12 of 15

MICROCEPHALY 8, PRIMARY, AUTOSOMAL RECESSIVE; MCPH8

primary autosomal recessive microcephaly 8

TSGA10; testis specific 10

7 of 15

SPERMATOGENIC FAILURE 26; SPGF26

spermatogenic failure 26

Functional Complementation Data

Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.

Interactions

Summary of Physical Interactions

esyN Network Diagram

Interactions Browser

View in Interactions Browser

Please see the Physical Interaction reports below for full details

protein-protein

Physical Interaction

Assay

References

anti tag coimmunoprecipitation, anti tag western blot, two hybrid

(Galletta et al., 2016)

(Galletta et al., 2016)

(Galletta et al., 2016)

anti tag coimmunoprecipitation, anti tag western blot, pull down, molecular weight estimation by staining, protein kinase assay, Identification by mass spectrometry, two hybrid

(Galletta et al., 2016)

two hybrid, pull down, western blot, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, anti tag western blot

(Galletta et al., 2016, Zheng et al., 2014)

pull down, autoradiography, cosedimentation, anti tag western blot, two hybrid, anti tag coimmunoprecipitation

(Fu et al., 2016, Galletta et al., 2016)

pull down, autoradiography, anti tag coimmunoprecipitation, anti tag western blot, two hybrid

(McLamarrah et al., 2020, Galletta et al., 2016, Dzhindzhev et al., 2014)

cosedimentation, anti tag western blot, two hybrid

(Fu et al., 2016, Galletta et al., 2016)

(Galletta et al., 2016)

Summary of Genetic Interactions

esyN Network Diagram

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

External Data

Linkouts

BioGRID - A database of protein and genetic interactions.

64969

DroID - A comprehensive database of gene and protein interactions.

FBgn0036480

InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.

39647

MIST (protein-protein) - An integrated Molecular Interaction Database

Cep135

Pathways

Signaling Pathways (FlyBase)

Metabolic Pathways

External Data

Linkouts

Genomic Location and Detailed Mapping Data

Chromosome (arm)

3L

Recombination map

3-42

Cytogenetic map

Sequence location

3L:15,116,737..15,128,029 [+]

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

71B5-71B5

Limits computationally determined from genome sequence between P{lacW}cp309^s2172&P{lacW}l(3)j2A2^j2A2 and P{EP}Tfb2^EP572

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

3-42

(FlyBase, 2016)

3-36.6

(Comeron et al., 2012)

Left of (cM)

Right of (cM)

Notes

Stocks and Reagents

Stocks (9)

85047

w¹¹¹⁸; PBac{PB}Cep135^c04199

65357

y¹ sc^* v¹ sev²¹; P{TRiP.HMC06109}attP40

24738

w¹¹¹⁸; Mi{ET1}Cep135^MB04996 CG16959^MB04996/TM6C, cu¹ Sb¹

60183

y¹ w^*; Mi{PT-GFSTF.2}Cep135^{MI02509-GFSTF.2}/TM3, Sb¹ Ser¹

66853

y¹ w^*; Mi{Trojan-GAL4.2}Cep135^{MI02509-TG4.2} CG16959^{MI02509-TG4.2-X}

35993

y¹ w^*; Mi{MIC}Cep135^MI02509 CG16959^MI02509/TM3, Sb¹ Ser¹

v14194

w¹¹¹⁸; P{GD6121}v14194

v14195

w¹¹¹⁸; P{GD6121}v14195

v341984

P{hsFLP}1, y¹ w¹¹¹⁸; P{HD_CFD01323}attP40/CyO-GFP

Genomic Clones (22)

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones (21)

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequenced

BDGP DGC clones

LD35990

Other clones

Drosophila Genomics Resource Center cDNA clones

For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

FBgn0036480

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi and Array Information

Linkouts

DRSC - Results frm RNAi screens

FBgn0036480

GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents

39647

Antibody Information

Laboratory Generated Antibodies

polyclonal

(Fu et al., 2016, Carvalho-Santos et al., 2012, Roque et al., 2012, Mottier-Pavie and Megraw, 2009)

Commercially Available Antibodies

Other Information

Relationship to Other Genes

Source for database identify of

Source for identity of: Cep135 CG17081

(Dobbelaere et al., 2008)

Source for database merge of

Additional comments

Other Comments

Cep135 is required for the early steps of central microtubule pair formation in the flagellar axoneme during spermatogenesis.

(Carvalho-Santos et al., 2012)

Cep135 is not essential for cartwheel assembly or for establishing the ninefold symmetry of centrioles; rather, it appears to stabilize the connection betwen inner and outer centriole components.

(Roque et al., 2012)

Cep135 regulates centriole, basal body and motile cilium assembly.

(Mottier-Pavie and Megraw, 2009)

Cep135 is involved in centriole duplication and is required for efficient recruitment of pericentriolar material.

(Dobbelaere et al., 2008)

Origin and Etymology

Discoverer

Etymology

Identification

External Crossreferences and Linkouts ( 37 )

Sequence Crossreferences

NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.

39647

GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.

GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.

RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.

UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information

Other crossreferences

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0036480

Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones

FBgn0036480

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

Cep135_1

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG17081

Flygut - An atlas of the Drosophila adult midgut

FBgn0036480

GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents

39647

iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)

TC031105

KEGG Genes - Molecular building blocks of life in the genomic space.

Dmel_CG17081

modMine - A data warehouse for the modENCODE project

FBgn0036480

Linkouts

BioGRID - A database of protein and genetic interactions.

64969

DroID - A comprehensive database of gene and protein interactions.

FBgn0036480

DRSC - Results frm RNAi screens

FBgn0036480

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

FBgn0036480

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

CG17081-RA

FlyCyc Genes - Genes from a BioCyc PGDB for Dmel

FBGN0036480

FlyMine - An integrated database for Drosophila genomics

FBgn0036480

Interactive Fly - A cyberspace guide to Drosophila development and metazoan evolution

Interactive Fly

InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.

39647

MIST (protein-protein) - An integrated Molecular Interaction Database

Cep135

Synonyms and Secondary IDs (14)

Reported As

Symbol Synonym

BLD10

(Jana et al., 2018)

Bld-10

(Zheng et al., 2014)

Bld10

(Ito et al., 2019, Lattao et al., 2017, Jana et al., 2016, Khire et al., 2016, Saurya et al., 2016, Homem et al., 2015, Khire et al., 2015, Lerit et al., 2015, Dzhindzhev et al., 2014, Carvalho-Santos et al., 2012, Fabian and Brill, 2012, Nguyen et al., 2011, Dzhindzhev et al., 2010)

Bld10p

(Blachon et al., 2009)

CEP135

(Naveed et al., 2018, Carvalho-Santos et al., 2010)

CG17081

(Balmer et al., 2015, Chen et al., 2012, Japanese National Institute of Genetics, 2012.5.21, Zhang et al., 2010, Mottier-Pavie and Megraw, 2009, Perkins et al., 2009, Dobbelaere et al., 2008)

Cep135

(McLamarrah et al., 2020, Tillery et al., 2018, Lattao et al., 2017, Galletta et al., 2016, Gene Disruption Project members, 2016-, Saurya et al., 2016, Fu et al., 2015, Gene Disruption Project members, 2015-, Homem et al., 2015, Franz et al., 2013, Roque et al., 2012, Wasbrough et al., 2010, Wasbrough et al., 2010, Blachon et al., 2008)

DBld10

(Gogendeau and Basto, 2010)

DCep135

(Stevens et al., 2010, Dobbelaere et al., 2008)

DCep135/Bld10

(Stevens et al., 2010)

DmBLD10

(Carvalho-Santos et al., 2010)

bld10

(Zheng et al., 2020, Zheng et al., 2016, Chen et al., 2015, Singh et al., 2014, Fabian and Brill, 2012, Blachon et al., 2009, Mottier-Pavie and Megraw, 2009)

dbld10

(Blachon et al., 2009, Blachon et al., 2008)

Name Synonyms

CG17081

Centrosomal protein 135kDa

Cep135

(Wasbrough et al., 2010)

Secondary FlyBase IDs

Datasets (0)

Study focus (0)

Experimental Role

Project

Project Type

Title

References (72)