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Gene Dmel\CG4877

General Information
Symbol	Dmel\CG4877	Species	D. melanogaster
Name		Annotation symbol	CG4877
Feature type	protein_coding_gene	FlyBase ID	FBgn0036624
Gene Model Status	Current	Stock availability	2 publicly available
Genomic Location
Chromosome (arm)	3L	Recombination map
Cytogenetic map	72E4-72E4	Sequence location	3L:16,379,440..16,383,924 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG4877 (FBgn0036624). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function: calcium-dependent phospholipid binding; calcium ion binding; zinc ion binding. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Annexin; Zinc finger, MYND-type. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 00-06 hour embryonic stages. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: larval central nervous system, larval hindgut, larval/adult salivary gland, larval trachea, adult ovary. Comments on Affy2 ProbeSet: ProbeSet 1641440_a_at completely aligns to an exonic region common to each of the 2 FlyBase-annotated transcript isoforms of CG4877. Gene sequence location is 3L:16379440..16383924.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2011_10
FB2012_01	Sequence features BKN24021 HFA10454 HFA10443
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 72E4-72E4   Limits computationally determined from genome sequence between P{lacW}l(3)s3123s3123 and P{lacW}l(3)j10E8j10E8&P{PZ}l(3)1053210532
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG4877 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.40 Putative intron in exon 3 with unconventional splice sites suggested by GenBank record AY061106=
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG4877-RA FBtr0075387  NM_168664   4070   1117 CG4877-RB FBtr0075386  NM_140632   4001   1117
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG4877-PA   FBpp0075145   125.5   1117   9.74     NP_730163   AAF49470 CG4877-PB   FBpp0075144   125.5   1117   9.74     NP_648889   AAF49469
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Zinc finger, MYND-type (IPR002893) Annexin (IPR001464)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA440449   AA539454   AA539851   AE014296 AAF49469   AE014296 AAF49470   AI109040   AI389494   AI456849   AY061106   BF500957   BG637973   BG638817   BI231831   BT021383 AAX33531   CK659990   CO178430   CO187825   CO269975   CO275284   CO276031   CO306613   CO323835   CO328524   CO328531   CO342133   EC076968   EC080578   EC197249   EC197275   EC212063   EC254789   GH946355   GH951721   GH953476   GH955794   GH960617   GH961226   GH967209   GH967628   GH969105   GH970310   GH970565   GH972392   GH976302   GH980522   GH982149   GH983822
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q95RV6 Q9VV52
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0036624    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0036624 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 00-06 hour embryonic stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0036624 expression level Developmental Stage   Expression Level embryo 00-02hr    2594 embryo 02-04hr    2925 embryo 04-06hr    2412 embryo 06-08hr    1280 embryo 08-10hr    1215 embryo 10-12hr    616 embryo 12-14hr    950 embryo 14-16hr    879 embryo 16-18hr    718 embryo 18-20hr    339 embryo 20-22hr    1351 embryo 22-24hr    1102 larva L1    376 larva L2    404 larva L3 12hr old    350 larva L3 puffstage 1-2    366 larva L3 puffstage 3-6    681 larva L3 puffstage 7-9    842 white prepupae new    824 white prepupae 12hr    792 white prepupae 24hr    1115 pupae 2d postWPP    570 pupae 3d postWPP    180 pupae 4d postWPP    136 adult male 01day    213 adult male 05day    261 adult male 30day    253 adult female 01day    687 adult female 05day    1359 adult female 30day    1374 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (2594) embryo 02-04hr  (2925) embryo 04-06hr  (2412) embryo 06-08hr  (1280) embryo 08-10hr  (1215) embryo 10-12hr  (616) embryo 12-14hr  (950) embryo 14-16hr  (879) embryo 16-18hr  (718) embryo 18-20hr  (339) embryo 20-22hr  (1351) embryo 22-24hr  (1102) larva L1  (376) larva L2  (404) larva L3 12hr old  (350) larva L3 puffstage 1-2  (366) larva L3 puffstage 3-6  (681) larva L3 puffstage 7-9  (842) white prepupae new  (824) white prepupae 12hr  (792) white prepupae 24hr  (1115) pupae 2d postWPP  (570) pupae 3d postWPP  (180) pupae 4d postWPP  (136) adult male 01day  (213) adult male 05day  (261) adult male 30day  (253) adult female 01day  (687) adult female 05day  (1359) adult female 30day  (1374) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (2594) embryo 02-04hr  (2925) embryo 04-06hr  (2412) embryo 06-08hr    1280 embryo 08-10hr    1215 embryo 10-12hr    616 embryo 12-14hr    950 embryo 14-16hr    879 embryo 16-18hr    718 embryo 18-20hr    339 embryo 20-22hr    1351 embryo 22-24hr    1102 larva L1    376 larva L2    404 larva L3 12hr old    350 larva L3 puffstage 1-2    366 larva L3 puffstage 3-6    681 larva L3 puffstage 7-9    842 white prepupae new    824 white prepupae 12hr    792 white prepupae 24hr    1115 pupae 2d postWPP    570 pupae 3d postWPP    180 pupae 4d postWPP    136 adult male 01day    213 adult male 05day    261 adult male 30day    253 adult female 01day    687 adult female 05day    1359 adult female 30day    1374 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    2594 embryo 02-04hr    2925 embryo 04-06hr    2412 embryo 06-08hr    1280 embryo 08-10hr    1215 embryo 10-12hr    616 embryo 12-14hr    950 embryo 14-16hr    879 embryo 16-18hr    718 embryo 18-20hr    339 embryo 20-22hr    1351 embryo 22-24hr    1102 larva L1    376 larva L2    404 larva L3 12hr old    350 larva L3 puffstage 1-2    366 larva L3 puffstage 3-6    681 larva L3 puffstage 7-9    842 white prepupae new    824 white prepupae 12hr    792 white prepupae 24hr    1115 pupae 2d postWPP    570 pupae 3d postWPP    180 pupae 4d postWPP    136 adult male 01day    213 adult male 05day    261 adult male 30day    253 adult female 01day    687 adult female 05day    1359 adult female 30day    1374 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    2594 embryo 02-04hr    2925 embryo 04-06hr    2412 embryo 06-08hr    1280 embryo 08-10hr    1215 embryo 10-12hr    616 embryo 12-14hr    950 embryo 14-16hr    879 embryo 16-18hr    718 embryo 18-20hr    339 embryo 20-22hr    1351 embryo 22-24hr    1102 larva L1    376 larva L2    404 larva L3 12hr old    350 larva L3 puffstage 1-2    366 larva L3 puffstage 3-6    681 larva L3 puffstage 7-9    842 white prepupae new    824 white prepupae 12hr    792 white prepupae 24hr    1115 pupae 2d postWPP    570 pupae 3d postWPP    180 pupae 4d postWPP    136 adult male 01day    213 adult male 05day    261 adult male 30day    253 adult female 01day    687 adult female 05day    1359 adult female 30day    1374 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0036624 expression level Developmental Stage   Expression Level embryo 00-02hr    2594 embryo 02-04hr    2925 embryo 04-06hr    2412 embryo 06-08hr    1280 embryo 08-10hr    1215 embryo 10-12hr    616 embryo 12-14hr    950 embryo 14-16hr    879 embryo 16-18hr    718 embryo 18-20hr    339 embryo 20-22hr    1351 embryo 22-24hr    1102 larva L1    376 larva L2    404 larva L3 12hr old    350 larva L3 puffstage 1-2    366 larva L3 puffstage 3-6    681 larva L3 puffstage 7-9    842 white prepupae new    824 white prepupae 12hr    792 white prepupae 24hr    1115 pupae 2d postWPP    570 pupae 3d postWPP    180 pupae 4d postWPP    136 adult male 01day    213 adult male 05day    261 adult male 30day    253 adult female 01day    687 adult female 05day    1359 adult female 30day    1374 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (2594) embryo 02-04hr  (2925) embryo 04-06hr  (2412) embryo 06-08hr  (1280) embryo 08-10hr  (1215) embryo 10-12hr  (616) embryo 12-14hr  (950) embryo 14-16hr  (879) embryo 16-18hr  (718) embryo 18-20hr  (339) embryo 20-22hr  (1351) embryo 22-24hr  (1102) larva L1  (376) larva L2  (404) larva L3 12hr old  (350) larva L3 puffstage 1-2  (366) larva L3 puffstage 3-6  (681) larva L3 puffstage 7-9  (842) white prepupae new  (824) white prepupae 12hr  (792) white prepupae 24hr  (1115) pupae 2d postWPP  (570) pupae 3d postWPP  (180) pupae 4d postWPP  136 adult male 01day  (213) adult male 05day  (261) adult male 30day  (253) adult female 01day  (687) adult female 05day  (1359) adult female 30day  (1374) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (2594) embryo 02-04hr  (2925) embryo 04-06hr  2412 embryo 06-08hr    1280 embryo 08-10hr    1215 embryo 10-12hr    616 embryo 12-14hr    950 embryo 14-16hr    879 embryo 16-18hr    718 embryo 18-20hr    339 embryo 20-22hr    1351 embryo 22-24hr    1102 larva L1    376 larva L2    404 larva L3 12hr old    350 larva L3 puffstage 1-2    366 larva L3 puffstage 3-6    681 larva L3 puffstage 7-9    842 white prepupae new    824 white prepupae 12hr    792 white prepupae 24hr    1115 pupae 2d postWPP    570 pupae 3d postWPP    180 pupae 4d postWPP    136 adult male 01day    213 adult male 05day    261 adult male 30day    253 adult female 01day    687 adult female 05day    1359 adult female 30day    1374 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    2594 embryo 02-04hr    2925 embryo 04-06hr    2412 embryo 06-08hr    1280 embryo 08-10hr    1215 embryo 10-12hr    616 embryo 12-14hr    950 embryo 14-16hr    879 embryo 16-18hr    718 embryo 18-20hr    339 embryo 20-22hr    1351 embryo 22-24hr    1102 larva L1    376 larva L2    404 larva L3 12hr old    350 larva L3 puffstage 1-2    366 larva L3 puffstage 3-6    681 larva L3 puffstage 7-9    842 white prepupae new    824 white prepupae 12hr    792 white prepupae 24hr    1115 pupae 2d postWPP    570 pupae 3d postWPP    180 pupae 4d postWPP    136 adult male 01day    213 adult male 05day    261 adult male 30day    253 adult female 01day    687 adult female 05day    1359 adult female 30day    1374 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    2594 embryo 02-04hr    2925 embryo 04-06hr    2412 embryo 06-08hr    1280 embryo 08-10hr    1215 embryo 10-12hr    616 embryo 12-14hr    950 embryo 14-16hr    879 embryo 16-18hr    718 embryo 18-20hr    339 embryo 20-22hr    1351 embryo 22-24hr    1102 larva L1    376 larva L2    404 larva L3 12hr old    350 larva L3 puffstage 1-2    366 larva L3 puffstage 3-6    681 larva L3 puffstage 7-9    842 white prepupae new    824 white prepupae 12hr    792 white prepupae 24hr    1115 pupae 2d postWPP    570 pupae 3d postWPP    180 pupae 4d postWPP    136 adult male 01day    213 adult male 05day    261 adult male 30day    253 adult female 01day    687 adult female 05day    1359 adult female 30day    1374 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0036624    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0036624 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: larval central nervous system, larval hindgut, larval/adult salivary gland, larval trachea, adult ovary. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0036624 expression level Tissue   Expression Level Larval Central Nervous System    335.65 Larval Midgut    54.6 Larval Hindgut    102.3 Larval Malpighian Tubules    73.9 Larval Fat Body    50.7 Larval Salivary Gland    173.5 Larval Trachea    103.5 Larval Carcass    66.6 Adult Head    51 Adult Eye    55.65 Adult Brain    95.6 Adult Thoracic-Abdominal Ganglion    82.7 Adult Crop    56.8 Adult Midgut    47.8 Adult Hindgut    55.8 Adult Malpighian Tubules    50.1 Adult Fat Body    53.4 Adult Salivary Gland    115.1 Adult Heart    36.35 Adult VirginFemale Spermatheca    48 Adult InseminatedFemale Spermatheca    64.8 Adult Ovary    262 Adult Testis    55.3 Adult Male Accessory Gland    96.5 Adult Carcass    41.7 Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    335.65 Larval Midgut    54.6 Larval Hindgut    102.3 Larval Malpighian Tubules    73.9 Larval Fat Body    50.7 Larval Salivary Gland    173.5 Larval Trachea    103.5 Larval Carcass    66.6 Adult Head    51 Adult Eye    55.65 Adult Brain    95.6 Adult Thoracic-Abdominal Ganglion    82.7 Adult Crop    56.8 Adult Midgut    47.8 Adult Hindgut    55.8 Adult Malpighian Tubules    50.1 Adult Fat Body    53.4 Adult Salivary Gland    115.1 Adult Heart    36.35 Adult VirginFemale Spermatheca    48 Adult InseminatedFemale Spermatheca    64.8 Adult Ovary    262 Adult Testis    55.3 Adult Male Accessory Gland    96.5 Adult Carcass    41.7 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    335.65 Larval Midgut    54.6 Larval Hindgut    102.3 Larval Malpighian Tubules    73.9 Larval Fat Body    50.7 Larval Salivary Gland    173.5 Larval Trachea    103.5 Larval Carcass    66.6 Adult Head    51 Adult Eye    55.65 Adult Brain    95.6 Adult Thoracic-Abdominal Ganglion    82.7 Adult Crop    56.8 Adult Midgut    47.8 Adult Hindgut    55.8 Adult Malpighian Tubules    50.1 Adult Fat Body    53.4 Adult Salivary Gland    115.1 Adult Heart    36.35 Adult VirginFemale Spermatheca    48 Adult InseminatedFemale Spermatheca    64.8 Adult Ovary    262 Adult Testis    55.3 Adult Male Accessory Gland    96.5 Adult Carcass    41.7 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    335.65 Larval Midgut    54.6 Larval Hindgut    102.3 Larval Malpighian Tubules    73.9 Larval Fat Body    50.7 Larval Salivary Gland    173.5 Larval Trachea    103.5 Larval Carcass    66.6 Adult Head    51 Adult Eye    55.65 Adult Brain    95.6 Adult Thoracic-Abdominal Ganglion    82.7 Adult Crop    56.8 Adult Midgut    47.8 Adult Hindgut    55.8 Adult Malpighian Tubules    50.1 Adult Fat Body    53.4 Adult Salivary Gland    115.1 Adult Heart    36.35 Adult VirginFemale Spermatheca    48 Adult InseminatedFemale Spermatheca    64.8 Adult Ovary    262 Adult Testis    55.3 Adult Male Accessory Gland    96.5 Adult Carcass    41.7 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0036624 expression level Tissue   Expression Level Larval Central Nervous System    335.65 Larval Midgut    54.6 Larval Hindgut    102.3 Larval Malpighian Tubules    73.9 Larval Fat Body    50.7 Larval Salivary Gland    173.5 Larval Trachea    103.5 Larval Carcass    66.6 Adult Head    51 Adult Eye    55.65 Adult Brain    95.6 Adult Thoracic-Abdominal Ganglion    82.7 Adult Crop    56.8 Adult Midgut    47.8 Adult Hindgut    55.8 Adult Malpighian Tubules    50.1 Adult Fat Body    53.4 Adult Salivary Gland    115.1 Adult Heart    36.35 Adult VirginFemale Spermatheca    48 Adult InseminatedFemale Spermatheca    64.8 Adult Ovary    262 Adult Testis    55.3 Adult Male Accessory Gland    96.5 Adult Carcass    41.7 Expression Level Scale  None   Low   Moderate   High  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    335.65 Larval Midgut    54.6 Larval Hindgut    102.3 Larval Malpighian Tubules    73.9 Larval Fat Body    50.7 Larval Salivary Gland    173.5 Larval Trachea    103.5 Larval Carcass    66.6 Adult Head    51 Adult Eye    55.65 Adult Brain    95.6 Adult Thoracic-Abdominal Ganglion    82.7 Adult Crop    56.8 Adult Midgut    47.8 Adult Hindgut    55.8 Adult Malpighian Tubules    50.1 Adult Fat Body    53.4 Adult Salivary Gland    115.1 Adult Heart    36.35 Adult VirginFemale Spermatheca    48 Adult InseminatedFemale Spermatheca    64.8 Adult Ovary    262 Adult Testis    55.3 Adult Male Accessory Gland    96.5 Adult Carcass    41.7 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    335.65 Larval Midgut    54.6 Larval Hindgut    102.3 Larval Malpighian Tubules    73.9 Larval Fat Body    50.7 Larval Salivary Gland    173.5 Larval Trachea    103.5 Larval Carcass    66.6 Adult Head    51 Adult Eye    55.65 Adult Brain    95.6 Adult Thoracic-Abdominal Ganglion    82.7 Adult Crop    56.8 Adult Midgut    47.8 Adult Hindgut    55.8 Adult Malpighian Tubules    50.1 Adult Fat Body    53.4 Adult Salivary Gland    115.1 Adult Heart    36.35 Adult VirginFemale Spermatheca    48 Adult InseminatedFemale Spermatheca    64.8 Adult Ovary    262 Adult Testis    55.3 Adult Male Accessory Gland    96.5 Adult Carcass    41.7 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    335.65 Larval Midgut    54.6 Larval Hindgut    102.3 Larval Malpighian Tubules    73.9 Larval Fat Body    50.7 Larval Salivary Gland    173.5 Larval Trachea    103.5 Larval Carcass    66.6 Adult Head    51 Adult Eye    55.65 Adult Brain    95.6 Adult Thoracic-Abdominal Ganglion    82.7 Adult Crop    56.8 Adult Midgut    47.8 Adult Hindgut    55.8 Adult Malpighian Tubules    50.1 Adult Fat Body    53.4 Adult Salivary Gland    115.1 Adult Heart    36.35 Adult VirginFemale Spermatheca    48 Adult InseminatedFemale Spermatheca    64.8 Adult Ovary    262 Adult Testis    55.3 Adult Male Accessory Gland    96.5 Adult Carcass    41.7 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    51   NA  Eye    55.65   NA  Brain    95.6   335.65  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    82.7   NA  Crop    56.8   54.6  Midgut    47.8   102.3  Hindgut    55.8   73.9  Malpighian Tubules    50.1   50.7  Fat Body    53.4   173.5  Salivary Gland    115.1   NA  Heart    36.35   103.5  Trachea    NA   NA  VirginFemale Spermatheca    48   NA  InseminatedFemale Spermatheca    64.8   NA  Ovary    262   NA  Testis    55.3   NA  Male Accessory Gland    96.5   66.6  Carcass    41.7 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_17
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0036624 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG4877-RB
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable, with Scer\GAL4pnr-MD237 CG4877GD11455 Phenotype manifest in Allele
Classical Alleles ( 0 )
For All Classical Alleles Show
Allele of CG4877 Class Mutagen Stocks Known lesion
Alleles Carried on Transgenic Constructs ( 2 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG4877 Class Mutagen Stocks Known lesion CG4877GD11455 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG4877HMS01012 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD11455} NA P{TRiP.HMS01012} NA
Insertions
	Type of insertions Name Expression data
Gene Ontology: Function, Process & Cellular Component ( 3 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 3 terms )
Molecular Function
CV term Evidence References
calcium-dependent phospholipid binding inferred from electronic annotation with InterPro:IPR001464 (FlyBase Curators et al., 2004-) calcium ion binding inferred from electronic annotation with InterPro:IPR001464 (FlyBase Curators et al., 2004-) zinc ion binding inferred from electronic annotation with InterPro:IPR002893 (FlyBase Curators et al., 2004-)
Biological Process ( 0 terms)
Cellular Component ( 0 terms)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG4877 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 65128 DroID - A comprehensive database of gene and protein interactions. • FBgn0036624 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 39821
Orthologs
Genome-wide drosophilid orthologs	Dana\GF24275 Dere\GG16002 Dgri\GH15890 Dmoj\GI16542 Dper\GL17860 Dpse\GA28518 Dsec\GM25634 Dsim\GD14638 Dvir\GJ12793 Dwil\GK14586 Dyak\GE23096
Curated drosophilid orthologs	Dpse\GA18495
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AGAP011638-PA Anopheles gambiae (mosquito) XP_001944901.1 Acyrthosiphon pisum (pea aphid) XP_001198353.1 Strongylocentrotus purpuratus (purple sea urchin) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • FBgn0240297 FBgn0236905 FBgn0216592 FBgn0200029 FBgn0186318 FBgn0180491 FBgn0249878 FBgn0155463 FBgn0139290 FBgn0123361 FBgn0108237 FBgn0101269
Stocks & Reagents
Stocks Listed in FlyBase ( 2 )
Bloomington	34395 y1 sc* v1; P{TRiP.HMS01012}attP2
VDRC	v21966 w1118; P{GD11455}v21966
Genomic Clones ( 1 )
	BACR09I16 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 44 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	LD09503 LD37257
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT16124 GH07539 GH20686 LD15296 LD17587 LD19130 LP18176 RE24368
Other clones	64975 120053 214353.58 CK01.40B.E9 CK01.126A.C8 CK01.126C.A4 EK033814 EK056703 EK097034 EK117008 EK119504 EK191632 EK251559 EK290816 EK290824 EP13919 LD10924 LD36996 RP004091336 RP004128937 RP004154676 RP004206467 RP004221341 RP004224752 RP004240487 RP004322560 RP004397975 RP004425124 RP004428834 RP004445779 RP004465655 RP004470261 RP004537985 RP004544384
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0036624 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 39821
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of	Source for merge of: CG4877 CG4689 (FlyBase, 1996-)
Additional comments	Source for merge of CG4877 CG4689 was a shared cDNA (date:010720). (FlyBase, 1996-)
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_140632 NM_168664 RefSeq (Proteins) • NP_648889 NP_730163 DDBJ / EMBL / GenBank • AAF49469 AAF49470 AAX33531 BT021383 Entrez Gene - A searchable database of RefSeq genes. • 39821 UniProtKB/TrEMBL • Q9VV52 Q95RV6
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Zinc finger, MYND-type (IPR002893) Annexin (IPR001464)
Linkouts
	BioGRID - A database of protein and genetic interactions • 65128 DroID - A comprehensive database of gene and protein interactions. • FBgn0036624 DRSC - Results from RNAi screens. • FBgn0036624 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0036624 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG4877-RB FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0036624 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 39821 InParanoid A subset of ortholog calls from InParanoid. • AGAP011638-PA Anopheles gambiae (mosquito) XP_001944901.1 Acyrthosiphon pisum (pea aphid) XP_001198353.1 Strongylocentrotus purpuratus (purple sea urchin) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 39821 modMine - Data generated by the modENCODE project. • FBgn0036624 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • FBgn0240297 FBgn0236905 FBgn0216592 FBgn0200029 FBgn0186318 FBgn0180491 FBgn0249878 FBgn0155463 FBgn0139290 FBgn0123361 FBgn0108237 FBgn0101269
Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	CG4689 (Veraksa et al., 2002, ) CG4877 (Ni et al., 2011.7.19)
Name Synonym
Secondary FlyBase IDs
	FBgn0036625
References ( 12 )
Research paper	Veraksa et al., 2002, genesis 33(2): 67--76 DEAF-1 function is essential for the early embryonic development of Drosophila. [FBrf0151504] Jin et al., 2001, Nature Genetics 29(4): 389--395 The contributions of sex, genotype and age to transcriptional variance in Drosophila melanogaster. [FBrf0141676]
Supplementary material	The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518] Giot et al., 2003, Science 302(5651): Tables S1 to S7. [FBrf0166452]
Personal communication to FlyBase	Ni et al., 2011.7.19, TRiP germline vector pVALIUM21. TRiP germline vector pVALIUM21. [FBrf0214641] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] FlyBase Curators et al., 2004-, Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. [FBrf0174215]
FlyBase analysis	FlyBase, 1996-, FlyBase inference based on genome sequence analysis. FlyBase inference based on genome sequence analysis. [FBrf0104946] FlyBase, 1992-, FlyBase curation FlyBase curation. [FBrf0105495]
Computer file	BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. Berkeley Drosophila Genome Project. [FBrf0125078]
Automatic genome annotation	FamiliarityBreedsContempt, 1999.11, [Annotations performed at the Celera Jamboreee.] [Annotations performed at the Celera Jamboreee.] [FBrf0126705]