Gene model reviewed during 5.44
Gene model reviewed during 5.45
Low-frequency RNA-Seq exon junction(s) not annotated.
Annotated transcripts do not represent all supported alternative splices within 5' UTR.
Gene model reviewed during 5.55
In the ovaries, part of a complex composed of at least Panx, nxf2, piwi and Nxt1 (PubMed:31570835, PubMed:31219034, PubMed:31368590, PubMed:31384064). The complex is knowns as Panx-induced cotranscriptional silencing (PICTS) complex, Panx-nxf2-dependent TAP/p15 silencing (Pandas complex), SFiNX (silencing factor interacting nuclear export variant) or piwi-Panx-nxf2-p15 (PPNP) complex (PubMed:31570835, PubMed:31219034, PubMed:31368590, PubMed:31384064). Interacts (via TAP-C domain) with Panx (via NIR region); the interaction is direct (PubMed:31570835, PubMed:31219034, PubMed:31368590). Interacts (via NTF2 domain) with Nxt1; the interaction is direct and prevents Nxt1 binding to nucleoporins (PubMed:31368590). Interacts with sbr/Nxf1 (PubMed:31570835).
The RNA-binding domain is a non-canonical RNP-type domain.
The TAP-C domain (also known as UBA domain) mediates the interaction with Panx.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\nxf2 using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\nxf2 in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.