FB2020_06, released Dec 22, 2020

Gene: Dmel\Mip

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General Information
Symbol
Dmel\Mip
Species
D. melanogaster
Name
Myoinhibiting peptide precursor
Annotation Symbol
CG6456
Feature Type
protein_coding_gene
FlyBase ID
FBgn0036713
Gene Model Status
Current
Stock Availability
10 publicly available
Gene Snapshot
Contributions welcome
Other Summaries
Also Known As

drostatin-B2, AstB, AstB-1, myoinhibitory peptide, Allatostatin B

Key Links
Genomic Location
Cytogenetic map
74A5-74A5
Sequence location
3L:17,344,947..17,349,666 [-]
Recombination map

3-45

RefSeq locus
NT_037436 REGION:17344947..17349666
Sequence
Get Decorated FASTA
Genomic Maps
Other Genome Views
The following external sites may use different assemblies or annotations than FlyBase.
NCBI
UCSC
Ensembl
PopFly
Function
GO Summary Ribbons
Gene Ontology (GO) Annotations (8 terms)
Molecular Function (3 terms)
Terms Based on Experimental Evidence (2 terms)
CV Term
Evidence
References
enables G protein-coupled receptor binding
inferred from physical interaction with FLYBASE:SPR; FB:FBgn0029768
(Kim et al., 2010)
enables signaling receptor binding
inferred from direct assay
(assigned by UniProt )
(Williamson et al., 2001)
Terms Based on Predictions or Assertions (1 term)
CV Term
Evidence
References
enables neuropeptide hormone activity
non-traceable author statement
(Hewes and Taghert, 2001, vanden Broeck, 2001)
Biological Process (4 terms)
Terms Based on Experimental Evidence (3 terms)
CV Term
Evidence
References
involved_in G protein-coupled receptor signaling pathway
inferred from direct assay
(Kim et al., 2010)
involved_in negative regulation of eating behavior
inferred from mutant phenotype
(Min et al., 2016)
involved_in neuropeptide signaling pathway
inferred from direct assay
(assigned by UniProt )
(Williamson et al., 2001)
Terms Based on Predictions or Assertions (2 terms)
CV Term
Evidence
References
involved_in negative regulation of juvenile hormone biosynthetic process
non-traceable author statement
(assigned by UniProt )
(Lenz et al., 2000)
involved_in neuropeptide signaling pathway
non-traceable author statement
(vanden Broeck, 2001)
Cellular Component (1 term)
Terms Based on Experimental Evidence (1 term)
CV Term
Evidence
References
located_in extracellular space
inferred from direct assay
(Reiher et al., 2011)
Terms Based on Predictions or Assertions (1 term)
CV Term
Evidence
References
located_in extracellular space
inferred from sequence model
(FlyBase Curators, 2011-)
Gene Group (FlyBase)
Protein Family (UniProt)
-
Protein Signatures (InterPro)
    -
    Summaries
    Gene Group (FlyBase)
    NEUROPEPTIDES -
    Neuropeptides are secreted into the extracellular space where they interact with cell surface receptors (usually G protein coupled receptors). They are extremely diverse, acting as neurotransmitters, neuromodulators, hormones or growth factors. (Adapted from FBrf0211443 and PMID:27813667).
    Protein Function (UniProtKB)
    Ligand for the sex peptide receptor (SPR) (PubMed:20308537, PubMed:20458515, PubMed:25333796). Stabilizes sleep and maintains sleep homeostasis to inhibit the activity of wake-promoting circuits, such as those that involve the pigment dispersing factor (pdf) neurons. Regulated by the circadian clock network and pathways associated with a sleep homeostat (PubMed:25333796). May also have a regulatory role in gut motility (PubMed:11181081).
    (UniProt, Q9VVF7)
    Summary (Interactive Fly)

    ancestral ligand for the Sex peptide receptor - acts directly in the polyamine-detecting olfactory and taste neurons - regulation of polyamine attraction, stabilization of sleep

    Gene Model and Products
    Number of Transcripts
    1
    Number of Unique Polypeptides
    1

    Please see the JBrowse view of Dmel\Mip for information on other features

    To submit a correction to a gene model please use the Contact FlyBase form

    Protein Domains (via Pfam)
    Isoform displayed:
    Pfam protein domains
    InterPro name
    classification
    start
    end
    Protein Domains (via SMART)
    Isoform displayed:
    SMART protein domains
    InterPro name
    classification
    start
    end
    Comments on Gene Model

    Low-frequency RNA-Seq exon junction(s) not annotated.

    Gene model reviewed during 5.45

    Sequence Ontology: Class of Gene
    nuclear_gene
    protein_coding_gene
    Transcript Data
    Annotated Transcripts
    Name
    FlyBase ID
    RefSeq ID
    Length (nt)
    Assoc. CDS (aa)
    Mip-RA
    FBtr0075241
    NM_140714
    1396
    211
    Additional Transcript Data and Comments
    Reported size (kB)
    Comments
    External Data
    Crossreferences
    Polypeptide Data
    Annotated Polypeptides
    Name
    FlyBase ID
    Predicted MW (kDa)
    Length (aa)
    Theoretical pI
    RefSeq ID
    GenBank
    Mip-PA
    FBpp0075003
    23.4
    211
    9.51
    NP_648971
    AAF49354
    Polypeptides with Identical Sequences

    There is only one protein coding transcript and one polypeptide associated with this gene

    Additional Polypeptide Data and Comments
    Reported size (kDa)
    Comments

    Small Mip-derived neuropeptides identified by 2D capillary LC/ESI-MS/MS: AWKSMNVAW, DQWQKLHGGW-amide.

    (Baggerman et al., 2005)

    Small Mip-derived neuropeptides identified by LC-MS/MS: AWKSMNVAW-amide, DQWQKLHGGW-amide.

    (Baggerman et al., 2002)
    External Data
    Crossreferences
    Linkouts
    Sequences Consistent with the Gene Model
    Mapped Features

    Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Mip using the Feature Mapper tool.

    External Data
    Crossreferences
    Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
    Linkouts
    Expression Data
    Expression Summary Ribbons
    Colored tiles in ribbon indicate that expression data has been curated by FlyBase for that anatomical location. Colorless tiles indicate that there is no curated data for that location.
    For complete stage-specific expression data, view the modENCODE Development RNA-Seq section under High-Throughput Expression below.
    Transcript Expression
    in situ
    Stage
    Tissue/Position (including subcellular localization)
    Reference
    embryonic stage 13 -- 16
    embryonic/larval midgut
    (Fisher et al., 2012)
    ventral nerve cord
    (Fisher et al., 2012)
    adult stage
    adult brain | restricted
    (Min et al., 2016)
    adult antennal lobe | restricted
    (Min et al., 2016)
    adult subesophageal zone | restricted
    (Min et al., 2016)
    lobe system of adult mushroom body | restricted
    (Min et al., 2016)
    superior medial protocerebrum | restricted
    (Min et al., 2016)
    calyx of adult mushroom body | restricted
    (Min et al., 2016)
    posterior superior lateral protocerebrum | restricted
    (Min et al., 2016)
    embryonic stage 16 -- 17
    VUM4 interneuron of embryonic labial segment
    (Fontana and Crews, 2012)
    RNA-seq
    Stage
    Tissue/Position (including subcellular localization)
    Reference
    embryonic stage 16
    ventral midline of embryo
    (Fontana and Crews, 2012)
    Additional Descriptive Data

    Mip transcript is co-expressed with Mip protein in 52 neurons of the adult brain.

    (Min et al., 2016)

    Mip is expressed in one cell in the midline of the mandibular segment and one cell in the midline of the labial segment that was identified as VUM interneuron 1 (iVUM4 in paper).

    (Fontana and Crews, 2012)
    Marker for
     
    Subcellular Localization
    CV Term
    Polypeptide Expression
    immunolocalization
    Stage
    Tissue/Position (including subcellular localization)
    Reference
    adult stage
    adult brain | restricted
    (Min et al., 2016, Kahsai and Winther, 2011, Carlsson et al., 2010)
    adult antennal lobe glomerulus | subset
    (Carlsson et al., 2010)
    fan-shaped body | restricted
    (Kahsai and Winther, 2011)
    adult pars intercerebralis
    (Kahsai and Winther, 2011)
    adult optic lobe
    (Kahsai and Winther, 2011)
    adult gnathal ganglion
    (Kahsai and Winther, 2011)
    midgut

    Comment: in posterior midgut, weak

    (Veenstra et al., 2008)
    adult antennal lobe | restricted
    (Min et al., 2016)
    adult subesophageal zone | restricted
    (Min et al., 2016)
    superior medial protocerebrum | restricted
    (Min et al., 2016)
    lobe system of adult mushroom body | restricted
    (Min et al., 2016)
    calyx of adult mushroom body | restricted
    (Min et al., 2016)
    posterior superior lateral protocerebrum | restricted
    (Min et al., 2016)
    adult fruitless vMT1 neuron
    (Min et al., 2016)
    adult central nervous system
    (Kim et al., 2010)
    third instar larval stage
    embryonic/larval anterior midgut | posterior
    (Veenstra, 2009)
    embryonic/larval copper cell
    (Veenstra, 2009)
    embryonic/larval midgut large flat cell
    (Veenstra, 2009)
    larval midgut neutral region
    (Veenstra, 2009)
    larval midgut transition region
    (Veenstra, 2009)
    mass spectroscopy
    Stage
    Tissue/Position (including subcellular localization)
    Reference
    wandering third instar larval stage
    embryonic/larval central nervous system
    (Baggerman et al., 2005, Baggerman et al., 2002)
    third instar larval stage
    embryonic/larval midgut

    Comment: peptides

    (Reiher et al., 2011)
    adult stage
    adult midgut

    Comment: peptides

    (Reiher et al., 2011)
    Additional Descriptive Data

    Mip protein is expressed in around 70 neurons of the adult brain innervating the adult antennal lobe and subesophageal zone.

    (Min et al., 2016)

    Mip protein is detected in most layers of the fan-shaped body, which the authors identify as layers 2-7, in a columnar organisation. The strongest staining is observed in layer 5, where it co-localises with Scer\GAL4c205. Co-localisation with Scer\GAL4ChAT.7.4 is detected in a group of 4 neurons in the dorsolateral protocerebrum and their projections in the fan-shaped body.

    (Kahsai and Winther, 2011)

    Mip peptides were detected in extracts from adult and larval midguts.

    (Reiher et al., 2011)

    Mip protein is expressed in 10-15 local neurons that innervate most adult antennal lobe glomeruli. These neurons have their cell bodies in one lateral cluster. Four to five of these neurons co-express Scer\GAL4ChAT.7.4.

    (Carlsson et al., 2010)

    Strong immunoreactivity was observed in the adult CNS but not in male reproductive organs.

    (Kim et al., 2010)

    Mip is expressed in a group of 7-30 large endocrine cells in the larval anterior midgut in a region just before the copper cells of the middle midgut. It is also expressed in up to 20 smaller cells in the copper cell region that tend to more numerous at the posterior end of the middle midgut. It is also expressed in a group of cells in the anterior region of the posterior midgut

    (Veenstra, 2009)
    Marker for
     
    Subcellular Localization
    CV Term
    Evidence
    References
    located_in extracellular space
    inferred from direct assay
    (Reiher et al., 2011)
    Expression Deduced from Reporters
    High-Throughput Expression Data
    Associated Tools

    GBrowse - Visual display of RNA-Seq signals

    View Dmel\Mip in GBrowse 2
    RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region
    Bulk Downloads
    RNA-Seq RPKM values for all genes
    Reference
    See Gelbart and Emmert, 2013 for analysis details and data files for all genes.
    Developmental Proteome: Life Cycle
    Developmental Proteome: Embryogenesis
    External Data and Images
    Linkouts
    BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
    FLIGHT - Cell culture data for RNAi and other high-throughput technologies
    FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
    Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
    Flygut - An atlas of the Drosophila adult midgut
    Images
    FlyExpress - Embryonic expression images (BDGP data)
    • Stages(s) 13-16
    FlyBase Wiki
    Image Based Resources
    Alleles, Insertions, and Transgenic Constructs
    Classical and Insertion Alleles ( 11 )
    For All Classical and Insertion Alleles Show
     
    Other relevant insertions
    Transgenic Constructs ( 8 )
    For All Alleles Carried on Transgenic Constructs Show
    Transgenic constructs containing/affecting coding region of Mip
    Transgenic constructs containing regulatory region of Mip
    Deletions and Duplications ( 1 )
    Phenotypes
    Orthologs
    Downloads
    Download All DIOPT Orthologs
    Download All OrthoDB Orthologs
    Human Orthologs (via DIOPT v8.0)
    Homo sapiens (Human) (0)
    No records found.
    Model Organism Orthologs (via DIOPT v8.0)
    Mus musculus (laboratory mouse) (0)
    No records found.
    Rattus norvegicus (Norway rat) (0)
    No records found.
    Xenopus tropicalis (Western clawed frog) (0)
    No records found.
    Danio rerio (Zebrafish) (0)
    No records found.
    Caenorhabditis elegans (Nematode, roundworm) (1)
    Cele\nlp-38
    2 of 15
    Yes
    Yes
    Arabidopsis thaliana (thale-cress) (0)
    No records found.
    Saccharomyces cerevisiae (Brewer's yeast) (0)
    No records found.
    Schizosaccharomyces pombe (Fission yeast) (0)
    No records found.
    Ortholog(s) in Drosophila Species (via OrthoDB v9.1) ( EOG09190G56 )
    Organism
    Common Name
    Gene
    AAA Syntenic Ortholog
    Multiple Dmel Genes in this Orthologous Group
    Drosophila simulans
    Dsim\GD12414
    Drosophila sechellia
    Dsec\GM24340
    Drosophila erecta
    Dere\GG15820
    Drosophila yakuba
    Dyak\GE22160
    Drosophila ananassae
    Dana\GF24317
    Drosophila pseudoobscura pseudoobscura
    Dpse\GA19609
    Drosophila persimilis
    Dper\GL15492
    Drosophila willistoni
    Dwil\GK20345
    Drosophila virilis
    Dvir\GJ13034
    Drosophila mojavensis
    Dmoj\GI12893
    Drosophila grimshawi
    Dgri\GH14915
    Orthologs in non-Drosophila Dipterans (via OrthoDB v9.1) ( EOG09150AEK )
    Organism
    Common Name
    Gene
    Multiple Dmel Genes in this Orthologous Group
    Musca domestica
    House fly
    Mdoa\17018786
    Glossina morsitans
    Tsetse fly
    Gmor\GMOY012234
    Lucilia cuprina
    Australian sheep blowfly
    Lcup\FF38_07111
    Aedes aegypti
    Yellow fever mosquito
    Aaeg\AAEL012139
    Culex quinquefasciatus
    Southern house mosquito
    Cqui\CPIJ000669
    Orthologs in non-Dipteran Insects (via OrthoDB v9.1) ( EOG090W0OYP )
    Organism
    Common Name
    Gene
    Multiple Dmel Genes in this Orthologous Group
    Bombyx mori
    Silkmoth
    Bmor\BGIBMGA009464
    Danaus plexippus
    Monarch butterfly
    Dple\DPOGS204635-PA
    Heliconius melpomene
    Postman butterfly
    Hmel\HMEL010575
    Apis florea
    Little honeybee
    Aflo\2147606081
    Apis florea
    Little honeybee
    Aflo\2178826259
    Apis florea
    Little honeybee
    Aflo\2147583713
    Dendroctonus ponderosae
    Mountain pine beetle
    Dpod\YQE_03373
    Tribolium castaneum
    Red flour beetle
    Tcas\TC007661
    Pediculus humanus
    Human body louse
    Phum\PHUM005290
    Rhodnius prolixus
    Kissing bug
    Rpro\RPRC003421
    Cimex lectularius
    Bed bug
    Clec\CLEC001012
    Acyrthosiphon pisum
    Pea aphid
    Apim\ACYPI007510
    Orthologs in non-Insect Arthropods (via OrthoDB v9.1) ( EOG090X0P9F )
    Organism
    Common Name
    Gene
    Multiple Dmel Genes in this Orthologous Group
    Strigamia maritima
    European centipede
    Smar\SMAR007238
    Ixodes scapularis
    Black-legged tick
    Isca\MIP
    Ixodes scapularis
    Black-legged tick
    Isca\ISCW021391
    Stegodyphus mimosarum
    African social velvet spider
    Smim\KFM67054.1
    Tetranychus urticae
    Two-spotted spider mite
    Turt\tetur10g00930
    Daphnia pulex
    Water flea
    Dpux\DAPPUDRAFT_305794
    Orthologs in non-Arthropod Metazoa (via OrthoDB v9.1) ( EOG091G12MK )
    Organism
    Common Name
    Gene
    Multiple Dmel Genes in this Orthologous Group
    Strongylocentrotus purpuratus
    Purple sea urchin
    Spur\SPU_024381gn
    Strongylocentrotus purpuratus
    Purple sea urchin
    Spur\Sp-Hypp_1670
    Strongylocentrotus purpuratus
    Purple sea urchin
    Spur\Sp-Hypp_443
    Strongylocentrotus purpuratus
    Purple sea urchin
    Spur\SPU_009687gn
    Strongylocentrotus purpuratus
    Purple sea urchin
    Spur\SPU_006831gn
    Strongylocentrotus purpuratus
    Purple sea urchin
    Spur\SPU_012967gn
    Strongylocentrotus purpuratus
    Purple sea urchin
    Spur\SPU_003108gn
    Strongylocentrotus purpuratus
    Purple sea urchin
    Spur\Sp-Hypp_3030
    Strongylocentrotus purpuratus
    Purple sea urchin
    Spur\Sp-Hypp_795
    Strongylocentrotus purpuratus
    Purple sea urchin
    Spur\SPU_025101gn
    Strongylocentrotus purpuratus
    Purple sea urchin
    Spur\SPU_016182gn
    Ciona intestinalis
    Vase tunicate
    Cint\LOC100174990
    Ciona intestinalis
    Vase tunicate
    Cint\ENSCING00000002666
    Gallus gallus
    Domestic chicken
    Ggal\ENSGALG00000022947
    Gallus gallus
    Domestic chicken
    Ggal\ENSGALG00000008677
    Gallus gallus
    Domestic chicken
    Ggal\ENSGALG00000028514
    Gallus gallus
    Domestic chicken
    Ggal\ENSGALG00000000909
    Gallus gallus
    Domestic chicken
    Ggal\NEFH
    Gallus gallus
    Domestic chicken
    Ggal\ENSGALG00000000317
    Gallus gallus
    Domestic chicken
    Ggal\ENSGALG00000011306
    Gallus gallus
    Domestic chicken
    Ggal\ENSGALG00000000314
    Paralogs
    Downloads
    Download All DIOPT Paralogs
    Paralogs (via DIOPT v8.0)
    Drosophila melanogaster (Fruit fly) (0)
    No records found.
    Human Disease Associations
    FlyBase Human Disease Model Reports
      Disease Model Summary Ribbon
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Allele
      Disease
      Evidence
      References
      Potential Models Based on Orthology ( 0 )
      Human Ortholog
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Allele
      Disease
      Interaction
      References
      Disease Associations of Human Orthologs (via DIOPT v8.0 and OMIM)
      Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.
      Homo sapiens (Human)
      Gene name
      Score
      OMIM
      OMIM Phenotype
      DO term
      Complementation?
      Transgene?
      Functional Complementation Data
      Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.
      Interactions
      Summary of Physical Interactions
      esyN Network Diagram
      Show neighbor-neighbor interactions:
      Select Layout:
      Legend:
      Protein
      RNA
      Selected Interactor(s)
      Interactions Browser
      View in Interactions Browser
      Please see the Physical Interaction reports below for full details
      protein-protein
      Physical Interaction
      Assay
      References
      Mip - SPR
      phenotype-based detection assay
      (Kim et al., 2010)
      Mip - awd
      experimental knowledge based
      (Guruharsha et al., 2011)
      Mip - regucalcin
      experimental knowledge based
      (Guruharsha et al., 2011)
      Summary of Genetic Interactions
      esyN Network Diagram
      Starting gene(s)
      Interaction type
      Interacting gene(s)
      Reference
      Starting gene(s)
      Interaction type
      Interacting gene(s)
      Reference
      External Data
      Linkouts
      DroID - A comprehensive database of gene and protein interactions.
      MIST (protein-protein) - An integrated Molecular Interaction Database
      Pathways
      Signaling Pathways (FlyBase)
      Metabolic Pathways
      External Data
      Linkouts
      Genomic Location and Detailed Mapping Data
      Chromosome (arm)
      3L
      Recombination map

      3-45

      Cytogenetic map
      74A5-74A5
      Sequence location
      3L:17,344,947..17,349,666 [-]
      FlyBase Computed Cytological Location
      Cytogenetic map
      Evidence for location
      74A5-74A5
      Limits computationally determined from genome sequence between P{PZ}Baldspot02281 and P{PZ}blot01658
      Experimentally Determined Cytological Location
      Cytogenetic map
      Notes
      References
      Experimentally Determined Recombination Data
      Location

      3-45

      (FlyBase, 2016)

      3-40.6

      (Comeron et al., 2012)
      Left of (cM)
      Right of (cM)
      Notes
      Stocks and Reagents
      Stocks (10)
      Genomic Clones (22)
      cDNA Clones (17)
       

      Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

      cDNA clones, fully sequenced
      BDGP DGC clones
      Other clones
      Drosophila Genomics Resource Center cDNA clones

      For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

      cDNA Clones, End Sequenced (ESTs)
      BDGP DGC clones
      Other clones
      RNAi and Array Information
      Linkouts
      DRSC - Results frm RNAi screens
      GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
      Antibody Information
      Laboratory Generated Antibodies
       

      polyclonal

      (Park et al., 2008)
      Commercially Available Antibodies
       
      Other Information
      Relationship to Other Genes
      Source for database identify of

      Source for identity of: MIP CG6456

      (FlyBase, 1996-)
      Source for database merge of
      Additional comments

      Source for identity of MIP CG6456 was sequence comparison ( date:001216 ).

      (FlyBase, 1996-)
      Other Comments

      Mip encodes a B-type prepro-allatostatin which contains one copy each of 5 putative allatostatins ("drostatin-B1" through to "drostatin-B5").

      (Williamson et al., 2001)
      Origin and Etymology
      Discoverer
      Etymology
      Identification
      External Crossreferences and Linkouts ( 32 )
      Sequence Crossreferences
      NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.
      GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
      GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.
      RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.
      UniProt/Swiss-Prot - Manually annotated and reviewed records of protein sequence and functional information
      Other crossreferences
      BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
      Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones
      Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
      Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
      Flygut - An atlas of the Drosophila adult midgut
      GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
      KEGG Genes - Molecular building blocks of life in the genomic space.
      modMine - A data warehouse for the modENCODE project
      Linkouts
      DPiM - Drosophila Protein interaction map
      DroID - A comprehensive database of gene and protein interactions.
      DRSC - Results frm RNAi screens
      FLIGHT - Cell culture data for RNAi and other high-throughput technologies
      FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
      FlyCyc Genes - Genes from a BioCyc PGDB for Dmel
      FlyMine - An integrated database for Drosophila genomics
      Interactive Fly - A cyberspace guide to Drosophila development and metazoan evolution
      MIST (protein-protein) - An integrated Molecular Interaction Database
      Synonyms and Secondary IDs (52)
      Reported As
      Symbol Synonym
      ASB
      (Veenstra et al., 2008)
      AST-B
      (Santos et al., 2007, Nassel, 2002)
      Ast-B
      (Park et al., 2008)
      AstB
      (Obniski et al., 2018, Nässel and Winther, 2010, Veenstra, 2009, Johnson et al., 2005)
      AstB-1
      (Birse et al., 2006, Johnson et al., 2004, Johnson et al., 2003)
      CG6456
      (Asahina and Anderson, 2013.9.23, Lemaitre and Miguel-Aliaga, 2013, Reiher et al., 2011, Ni et al., 2010.12.1, Keleman et al., 2009.8.5, Perkins et al., 2009.3.31, Yew et al., 2009, Holloway et al., 2008, Wegener and Gorbashov, 2008, Vanden Broeck et al., 2001)
      DAP-B
      (Williamson et al., 2001)
      DmMIP1
      (Kim et al., 2010)
      DmMIP2
      (Kim et al., 2010)
      DmMIP3
      (Kim et al., 2010)
      DmMIP4
      (Kim et al., 2010)
      DmMIP5
      (Kim et al., 2010)
      Drm-MIP
      (vanden Broeck, 2001)
      Drm-MIP-1
      (vanden Broeck, 2001)
      Drm-MIP-2
      (Baggerman et al., 2002, vanden Broeck, 2001)
      Drm-MIP-3
      (vanden Broeck, 2001)
      Drm-MIP-4
      (vanden Broeck, 2001)
      Drm-MIP-5
      (Baggerman et al., 2002, vanden Broeck, 2001)
      MIP
      (Nässel et al., 2019, Nässel, 2018, Sayin et al., 2018, Martelli et al., 2017, Chen et al., 2016, Kahsai and Winther, 2011, Kolodziejczyk and Nässel, 2011, Carlsson et al., 2010, Kim et al., 2010, Lajeunesse et al., 2010, Nässel and Winther, 2010, Poels et al., 2010, Veenstra, 2009, Veenstra et al., 2008, Vömel and Wegener, 2008, Vömel and Wegener, 2007, Bowser and Tobe, 2006, Ewer, 2006, Baggerman et al., 2005)
      MIP-1
      (Nässel and Winther, 2010)
      MIP-2
      (Nässel and Winther, 2010)
      MIP-3
      (Carlsson et al., 2010, Nässel and Winther, 2010)
      MIP-4
      (Nässel and Winther, 2010)
      MIP-5
      (Carlsson et al., 2010, Nässel and Winther, 2010)
      MIP1
      (Vandersmissen et al., 2013)
      MIP2
      (Vandersmissen et al., 2013)
      MIP3
      (Vandersmissen et al., 2013)
      MIP4
      (Vandersmissen et al., 2013)
      MIP5
      (Vandersmissen et al., 2013)
      Mip
      (Hung et al., 2020, Deng et al., 2019, Rao and Deng, 2019.10.23, Croset et al., 2018, Donlea et al., 2018, Jang et al., 2017, Transgenic RNAi Project members, 2017-, Crocker et al., 2016, Huang et al., 2016, Reid and O'Brochta, 2016, Lee et al., 2015, Asahina and Anderson, 2013.9.23, Kondo and Ueda, 2013, Kondo and Ueda, 2013, Lemaitre and Miguel-Aliaga, 2013, Thomas et al., 2012, Kahsai and Winther, 2011, Reiher et al., 2011, Veverytsa and Allan, 2011, Holloway et al., 2008, Wegener and Gorbashov, 2008, Santos et al., 2007)
      mip
      (Lin et al., 2019, Min et al., 2016, Marianes and Spradling, 2013, Vandersmissen et al., 2013, Melcher and Pankratz, 2005)
      Name Synonyms
      Allatostatin B
      (Nässel and Winther, 2010, Veenstra et al., 2008, Johnson et al., 2005)
      Allatostatin cricket-type
      (Nassel, 2002)
      Allostatin B
      (Lajeunesse et al., 2010)
      Drostatin-B1
      (Nassel, 2002)
      Drostatin-B2
      (Nassel, 2002)
      Drostatin-B3
      (Nassel, 2002)
      Drostatin-B4
      (Nassel, 2002)
      Drostatin-B5
      (Nassel, 2002)
      Mioinhibiting Peptide Precursor
      (Asahina and Anderson, 2013.9.23)
      Mip-like peptide
      (Baggerman et al., 2005)
      Myoinhibiting peptide
      (Kondo and Ueda, 2013)
      Myoinhibiting peptide precursor
      (Asahina et al., 2014, Baggerman et al., 2002)
      allatostatin (B-type)
      (Hewes and Taghert, 2001)
      allatostatin B
      (Veenstra, 2009, Park et al., 2008)
      allatostatin B-1
      (Birse et al., 2006)
      allatostatin-B
      (Hansen et al., 2011)
      allatostatin-B1
      (Jorgensen et al., 2006)
      drostatin-B2
      (Egerod et al., 2003, Egerod et al., 2003, Rosenkilde et al., 2003, Cazzamali and Grimmelikhuijzen, 2002, Iversen et al., 2002, Iversen et al., 2002)
      myoinhibiting peptide
      (Vömel and Wegener, 2008, Vömel and Wegener, 2007)
      myoinhibiting peptide precursor
      (Caers et al., 2012, Kahsai and Winther, 2011)
      myoinhibitory peptide
      (Vandersmissen et al., 2013, Kolodziejczyk and Nässel, 2011, Kim et al., 2006)
      Secondary FlyBase IDs
        Datasets (0)
        Study focus (0)
        Experimental Role
        Project
        Project Type
        Title
        References (100)