A Database of Drosophila Genes & Genomes

FB2012_01, released January 20th, 2012
 

Gene Dmel\Aut1

General Information
SymbolDmel\Aut1SpeciesD. melanogaster
NameAut1Annotation symbolCG6877
Feature typeprotein_coding_geneFlyBase IDFBgn0036813
Gene Model StatusCurrent Stock availability 5 publicly available
Also Known AsAtg3, Draut1
Genomic Location
Chromosome (arm)3LRecombination map
Cytogenetic map75D8-75D8Sequence location3L:18,741,808..18,743,583 [+]

Genomic Maps

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modENCODE GBrowse
detailed view
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Automatically generated summary

See sections below for more information
The gene Aut1 is referred to in FlyBase by the symbol Dmel\Aut1 (CG6877, FBgn0036813). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process: autophagy. 8 alleles are reported. The phenotypes of these alleles are annotated with: embryonic/larval fat body; autophagic vacuole. It has one annotated transcript and one annotated polypeptide. Protein features are: Autophagy-related protein 3; Autophagy-related protein 3, C-terminal; Autophagy-related protein 3, N-terminal. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-12 hour embryonic stages, during late larval stages, at stages throughout the pupal period. Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult organs/tissues expressed at moderate or high levels. Expression at high levels in the following post-embryonic organs or tissues: larval/adult midgut, larval Malpighian tubules, adult heart, larval fat body, virgin spermatheca. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult hindgut, adult Malpighian tubules, adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male accessory gland, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1635143_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of Aut1. Gene sequence location is 3L:18741808..18743583.

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Description
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This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms).
What does this section not display?
This section does not currently display links that were removed or gene model changes.
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FB2012_01
Sequence features
FB2011_10
All updates Click here to see a list of all updates to this record from FB2010_08 and on.
hide Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map
Evidence for location
75D8-75D8  
Limits computationally determined from genome sequence between P{PZ}W05014 and P{lacW}l(3)j14E7j14E7  
Experimentally Determined Cytological Location
Cytogenetic map
Notes
References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
hide Gene Model & Products
Please see the GBrowse view of Dmel\Aut1 for information on other features
To submit a correction to a gene model please use the Contact FlyBase form
detailed view FBtr0075088 FBtr0075055 FBtr0075087 FBtr0304627 FBtr0075086 FBpp0074855 FBpp0074822 FBti0112756 FBti0074804 FBti0125788_2 FBti0125788_1 FBti0044424 FBti0039531 FBti0125789
Comments on Gene Model
hide Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Associated CDS (aa)
FBtr0075055
  1200
  330
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
hide Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kDa)
Length (aa)
Theoretical pI
RefSeq ID
GenBank protein
FBpp0074822  
37.0  
330  
4.37  
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences
InterPro domains - A database of protein families, domains, and functional sites
hide Sequences Consistent with the Gene Model
DDBJ /
EMBL /
GenBank
DNA sequence
Protein sequence
Name
 
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL
hide Mapped Features
Mapped Features have been reorganized, please see this article for details.
Additional mapped features and mutations can be found on GBrowse or related reports.
Type
Symbol & Location
Additional Notes
References
hide External Data
Linkouts
Crossreferences
hide Expression Data
hideTranscript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
hidePolypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
hide High-Throughput Expression Data
or
Untitled Document detailed view Nufip-RA Aut1-RA ftz-f1-RC
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.

modENCODE Temporal Expression Data for FBgn0036813


   Styles
Linear
Logarithmic
Heatmap
   Scales
max expr for FBgn0036813
Very low expression bin max
Moderate expression bin max
High expression bin max
Extremely high expression bin max

Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-12 hour embryonic stages, during late larval stages, at stages throughout the pupal period.
[download data (TSV)]

Guide to modENCODE expression level colors
 
No expression (0 - 0)
 
Extremely low expression (1 - 10)
 
Very low expression (11 - 100)
 
Low expression (101 - 400)
 
Moderate expression (401 - 1400)
 
Moderately high expression (1401 - 4000)
 
High expression (4001 - 10000)
 
Very high expression (10001 - 100000)
 
Extremely high expression (100001 - 2000000)

Linear, scaled to maximum FBgn0036813 expression level
Developmental Stage   Expression Level
embryo 00-02hr
 
 4950
embryo 02-04hr
 
 7330
embryo 04-06hr
 
 6088
embryo 06-08hr
 
 5206
embryo 08-10hr
 
 4446
embryo 10-12hr
 
 4108
embryo 12-14hr
 
 3374
embryo 14-16hr
 
 3828
embryo 16-18hr
 
 2915
embryo 18-20hr
 
 1743
embryo 20-22hr
 
 1375
embryo 22-24hr
 
 1382
larva L1
 
 1914
larva L2
 
 1773
larva L3 12hr old
 
 1706
larva L3 puffstage 1-2
 
 3294
larva L3 puffstage 3-6
 
 4344
larva L3 puffstage 7-9
 
 4813
white prepupae new
 
 6434
white prepupae 12hr
 
 6487
white prepupae 24hr
 
 6141
pupae 2d postWPP
 
 4738
pupae 3d postWPP
 
 2489
pupae 4d postWPP
 
 1502
adult male 01day
 
 2434
adult male 05day
 
 2253
adult male 30day
 
 2447
adult female 01day
 
 3103
adult female 05day
 
 2864
adult female 30day
 
 3040
Expression Level Scale
 None 
 Extremely low 
 Very low 
 Low 
 Moderate 
 Moderately high 
 High 
Linear, scaled to Very low expression
Developmental Stage   Expression Level
embryo 00-02hr
 (4950)
embryo 02-04hr
 (7330)
embryo 04-06hr
 (6088)
embryo 06-08hr
 (5206)
embryo 08-10hr
 (4446)
embryo 10-12hr
 (4108)
embryo 12-14hr
 (3374)
embryo 14-16hr
 (3828)
embryo 16-18hr
 (2915)
embryo 18-20hr
 (1743)
embryo 20-22hr
 (1375)
embryo 22-24hr
 (1382)
larva L1
 (1914)
larva L2
 (1773)
larva L3 12hr old
 (1706)
larva L3 puffstage 1-2
 (3294)
larva L3 puffstage 3-6
 (4344)
larva L3 puffstage 7-9
 (4813)
white prepupae new
 (6434)
white prepupae 12hr
 (6487)
white prepupae 24hr
 (6141)
pupae 2d postWPP
 (4738)
pupae 3d postWPP
 (2489)
pupae 4d postWPP
 (1502)
adult male 01day
 (2434)
adult male 05day
 (2253)
adult male 30day
 (2447)
adult female 01day
 (3103)
adult female 05day
 (2864)
adult female 30day
 (3040)
Expression Level Scale
 None 
 Extremely low 
 Very low 
 Low 
Linear, scaled to Moderate expression
Developmental Stage   Expression Level
embryo 00-02hr
 (4950)
embryo 02-04hr
 (7330)
embryo 04-06hr
 (6088)
embryo 06-08hr
 (5206)
embryo 08-10hr
 (4446)
embryo 10-12hr
 (4108)
embryo 12-14hr
 (3374)
embryo 14-16hr
 (3828)
embryo 16-18hr
 (2915)
embryo 18-20hr
 (1743)
embryo 20-22hr
 
 1375
embryo 22-24hr
 
 1382
larva L1
 (1914)
larva L2
 (1773)
larva L3 12hr old
 (1706)
larva L3 puffstage 1-2
 (3294)
larva L3 puffstage 3-6
 (4344)
larva L3 puffstage 7-9
 (4813)
white prepupae new
 (6434)
white prepupae 12hr
 (6487)
white prepupae 24hr
 (6141)
pupae 2d postWPP
 (4738)
pupae 3d postWPP
 (2489)
pupae 4d postWPP
 1502
adult male 01day
 (2434)
adult male 05day
 (2253)
adult male 30day
 (2447)
adult female 01day
 (3103)
adult female 05day
 (2864)
adult female 30day
 (3040)
Expression Level Scale
 None 
 Extremely low 
 Very low 
 Low 
 Moderate 
 Moderately high 
Linear, scaled to High expression
Developmental Stage   Expression Level
embryo 00-02hr
 
 4950
embryo 02-04hr
 
 7330
embryo 04-06hr
 
 6088
embryo 06-08hr
 
 5206
embryo 08-10hr
 
 4446
embryo 10-12hr
 
 4108
embryo 12-14hr
 
 3374
embryo 14-16hr
 
 3828
embryo 16-18hr
 
 2915
embryo 18-20hr
 
 1743
embryo 20-22hr
 
 1375
embryo 22-24hr
 
 1382
larva L1
 
 1914
larva L2
 
 1773
larva L3 12hr old
 
 1706
larva L3 puffstage 1-2
 
 3294
larva L3 puffstage 3-6
 
 4344
larva L3 puffstage 7-9
 
 4813
white prepupae new
 
 6434
white prepupae 12hr
 
 6487
white prepupae 24hr
 
 6141
pupae 2d postWPP
 
 4738
pupae 3d postWPP
 
 2489
pupae 4d postWPP
 
 1502
adult male 01day
 
 2434
adult male 05day
 
 2253
adult male 30day
 
 2447
adult female 01day
 
 3103
adult female 05day
 
 2864
adult female 30day
 
 3040
Expression Level Scale
 None 
 Extremely low 
 Very low 
 Low 
 Moderate 
 Moderately high 
 High 
 Very high 
Linear, scaled to Extremely high expression
Developmental Stage   Expression Level
embryo 00-02hr
 
 4950
embryo 02-04hr
 
 7330
embryo 04-06hr
 
 6088
embryo 06-08hr
 
 5206
embryo 08-10hr
 
 4446
embryo 10-12hr
 
 4108
embryo 12-14hr
 
 3374
embryo 14-16hr
 
 3828
embryo 16-18hr
 
 2915
embryo 18-20hr
 
 1743
embryo 20-22hr
 
 1375
embryo 22-24hr
 
 1382
larva L1
 
 1914
larva L2
 
 1773
larva L3 12hr old
 
 1706
larva L3 puffstage 1-2
 
 3294
larva L3 puffstage 3-6
 
 4344
larva L3 puffstage 7-9
 
 4813
white prepupae new
 
 6434
white prepupae 12hr
 
 6487
white prepupae 24hr
 
 6141
pupae 2d postWPP
 
 4738
pupae 3d postWPP
 
 2489
pupae 4d postWPP
 
 1502
adult male 01day
 
 2434
adult male 05day
 
 2253
adult male 30day
 
 2447
adult female 01day
 
 3103
adult female 05day
 
 2864
adult female 30day
 
 3040
Expression Level Scale
 None 
 Extremely low 
 Very low 
 Low 
 Moderate 
 Moderately high 
 High 
 Very high 
 Extremely high 
log, scaled to maximum FBgn0036813 expression level
Developmental Stage   Expression Level
embryo 00-02hr
 
 4950
embryo 02-04hr
 
 7330
embryo 04-06hr
 
 6088
embryo 06-08hr
 
 5206
embryo 08-10hr
 
 4446
embryo 10-12hr
 
 4108
embryo 12-14hr
 
 3374
embryo 14-16hr
 
 3828
embryo 16-18hr
 
 2915
embryo 18-20hr
 
 1743
embryo 20-22hr
 
 1375
embryo 22-24hr
 
 1382
larva L1
 
 1914
larva L2
 
 1773
larva L3 12hr old
 
 1706
larva L3 puffstage 1-2
 
 3294
larva L3 puffstage 3-6
 
 4344
larva L3 puffstage 7-9
 
 4813
white prepupae new
 
 6434
white prepupae 12hr
 
 6487
white prepupae 24hr
 
 6141
pupae 2d postWPP
 
 4738
pupae 3d postWPP
 
 2489
pupae 4d postWPP
 
 1502
adult male 01day
 
 2434
adult male 05day
 
 2253
adult male 30day
 
 2447
adult female 01day
 
 3103
adult female 05day
 
 2864
adult female 30day
 
 3040
Expression Level Scale
 None 
 Extremely low 
 Very low 
 Low 
 Moderate 
 Moderately high 
 High 
 Very high 
log, scaled to Very low expression
Developmental Stage   Expression Level
embryo 00-02hr
 (4950)
embryo 02-04hr
 (7330)
embryo 04-06hr
 (6088)
embryo 06-08hr
 (5206)
embryo 08-10hr
 (4446)
embryo 10-12hr
 (4108)
embryo 12-14hr
 (3374)
embryo 14-16hr
 (3828)
embryo 16-18hr
 (2915)
embryo 18-20hr
 (1743)
embryo 20-22hr
 (1375)
embryo 22-24hr
 (1382)
larva L1
 (1914)
larva L2
 (1773)
larva L3 12hr old
 (1706)
larva L3 puffstage 1-2
 (3294)
larva L3 puffstage 3-6
 (4344)
larva L3 puffstage 7-9
 (4813)
white prepupae new
 (6434)
white prepupae 12hr
 (6487)
white prepupae 24hr
 (6141)
pupae 2d postWPP
 (4738)
pupae 3d postWPP
 (2489)
pupae 4d postWPP
 (1502)
adult male 01day
 (2434)
adult male 05day
 (2253)
adult male 30day
 (2447)
adult female 01day
 (3103)
adult female 05day
 (2864)
adult female 30day
 (3040)
Expression Level Scale
 None 
 Extremely low 
 Very low 
 Low 
log, scaled to Moderate expression
Developmental Stage   Expression Level
embryo 00-02hr
 (4950)
embryo 02-04hr
 (7330)
embryo 04-06hr
 (6088)
embryo 06-08hr
 (5206)
embryo 08-10hr
 (4446)
embryo 10-12hr
 (4108)
embryo 12-14hr
 (3374)
embryo 14-16hr
 (3828)
embryo 16-18hr
 (2915)
embryo 18-20hr
 1743
embryo 20-22hr
 
 1375
embryo 22-24hr
 
 1382
larva L1
 1914
larva L2
 1773
larva L3 12hr old
 1706
larva L3 puffstage 1-2
 (3294)
larva L3 puffstage 3-6
 (4344)
larva L3 puffstage 7-9
 (4813)
white prepupae new
 (6434)
white prepupae 12hr
 (6487)
white prepupae 24hr
 (6141)
pupae 2d postWPP
 (4738)
pupae 3d postWPP
 (2489)
pupae 4d postWPP
 1502
adult male 01day
 2434
adult male 05day
 2253
adult male 30day
 2447
adult female 01day
 (3103)
adult female 05day
 (2864)
adult female 30day
 (3040)
Expression Level Scale
 None 
 Extremely low 
 Very low 
 Low 
 Moderate 
 Moderately high 
log, scaled to High expression
Developmental Stage   Expression Level
embryo 00-02hr
 
 4950
embryo 02-04hr
 
 7330
embryo 04-06hr
 
 6088
embryo 06-08hr
 
 5206
embryo 08-10hr
 
 4446
embryo 10-12hr
 
 4108
embryo 12-14hr
 
 3374
embryo 14-16hr
 
 3828
embryo 16-18hr
 
 2915
embryo 18-20hr
 
 1743
embryo 20-22hr
 
 1375
embryo 22-24hr
 
 1382
larva L1
 
 1914
larva L2
 
 1773
larva L3 12hr old
 
 1706
larva L3 puffstage 1-2
 
 3294
larva L3 puffstage 3-6
 
 4344
larva L3 puffstage 7-9
 
 4813
white prepupae new
 
 6434
white prepupae 12hr
 
 6487
white prepupae 24hr
 
 6141
pupae 2d postWPP
 
 4738
pupae 3d postWPP
 
 2489
pupae 4d postWPP
 
 1502
adult male 01day
 
 2434
adult male 05day
 
 2253
adult male 30day
 
 2447
adult female 01day
 
 3103
adult female 05day
 
 2864
adult female 30day
 
 3040
Expression Level Scale
 None 
 Extremely low 
 Very low 
 Low 
 Moderate 
 Moderately high 
 High 
 Very high 
log, scaled to Extremely high expression
Developmental Stage   Expression Level
embryo 00-02hr
 
 4950
embryo 02-04hr
 
 7330
embryo 04-06hr
 
 6088
embryo 06-08hr
 
 5206
embryo 08-10hr
 
 4446
embryo 10-12hr
 
 4108
embryo 12-14hr
 
 3374
embryo 14-16hr
 
 3828
embryo 16-18hr
 
 2915
embryo 18-20hr
 
 1743
embryo 20-22hr
 
 1375
embryo 22-24hr
 
 1382
larva L1
 
 1914
larva L2
 
 1773
larva L3 12hr old
 
 1706
larva L3 puffstage 1-2
 
 3294
larva L3 puffstage 3-6
 
 4344
larva L3 puffstage 7-9
 
 4813
white prepupae new
 
 6434
white prepupae 12hr
 
 6487
white prepupae 24hr
 
 6141
pupae 2d postWPP
 
 4738
pupae 3d postWPP
 
 2489
pupae 4d postWPP
 
 1502
adult male 01day
 
 2434
adult male 05day
 
 2253
adult male 30day
 
 2447
adult female 01day
 
 3103
adult female 05day
 
 2864
adult female 30day
 
 3040
Expression Level Scale
 None 
 Extremely low 
 Very low 
 Low 
 Moderate 
 Moderately high 
 High 
 Very high 
 Extremely high 
Heatmap
Developmental Stage   Expression Level
embryo 00-02hr
 
 
embryo 02-04hr
 
 
embryo 04-06hr
 
 
embryo 06-08hr
 
 
embryo 08-10hr
 
 
embryo 10-12hr
 
 
embryo 12-14hr
 
 
embryo 14-16hr
 
 
embryo 16-18hr
 
 
embryo 18-20hr
 
 
embryo 20-22hr
 
 
embryo 22-24hr
 
 
larva L1
 
 
larva L2
 
 
larva L3 12hr old
 
 
larva L3 puffstage 1-2
 
 
larva L3 puffstage 3-6
 
 
larva L3 puffstage 7-9
 
 
white prepupae new
 
 
white prepupae 12hr
 
 
white prepupae 24hr
 
 
pupae 2d postWPP
 
 
pupae 3d postWPP
 
 
pupae 4d postWPP
 
 
adult male 01day
 
 
adult male 05day
 
 
adult male 30day
 
 
adult female 01day
 
 
adult female 05day
 
 
adult female 30day
 
 

FlyAtlas Anatomical Expression Data for FBgn0036813


   Styles
Linear
Logarithmic
Heatmap
Back-to-back
   Scales
max expr for FBgn0036813
Moderate expression bin max
High level expression bin max
Very high expression bin max

Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult organs/tissues expressed at moderate or high levels. Expression at high levels in the following post-embryonic organs or tissues: larval/adult midgut, larval Malpighian tubules, adult heart, larval fat body, virgin spermatheca. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult hindgut, adult Malpighian tubules, adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male accessory gland, larval/adult carcass.
[download data (TSV)]

Guide to FlyAtlas expression level colors
 
No expression (0 - 9.999)
 
Low expression (10 - 99.999)
 
Moderate expression (100 - 499.999)
 
High level expression (500 - 999.999)
 
Very high expression (1000 - 25000)

Linear, scaled to maximum FBgn0036813 expression level
Tissue   Expression Level
Larval Central Nervous System
 
 366.65
Larval Midgut
 
 739.7
Larval Hindgut
 
 246.9
Larval Malpighian Tubules
 
 592.3
Larval Fat Body
 
 607.4
Larval Salivary Gland
 
 278.1
Larval Trachea
 
 247.825
Larval Carcass
 
 229.825
Adult Head
 
 387
Adult Eye
 
 453.85
Adult Brain
 
 411.1
Adult Thoracic-Abdominal Ganglion
 
 384.1
Adult Crop
 
 247.1
Adult Midgut
 
 1020
Adult Hindgut
 
 338.2
Adult Malpighian Tubules
 
 460.2
Adult Fat Body
 
 360.8
Adult Salivary Gland
 
 266.6
Adult Heart
 
 528.025
Adult VirginFemale Spermatheca
 
 547.3
Adult InseminatedFemale Spermatheca
 
 493.5
Adult Ovary
 
 311.1
Adult Testis
 
 88.3
Adult Male Accessory Gland
 
 300.2
Adult Carcass
 
 340.7
Expression Level Scale
 None 
 Low 
 Moderate 
 High 
 Very high 
Linear, scaled to Moderate expression
Tissue   Expression Level
Larval Central Nervous System
 
 366.65
Larval Midgut
 (739.7)
Larval Hindgut
 
 246.9
Larval Malpighian Tubules
 (592.3)
Larval Fat Body
 (607.4)
Larval Salivary Gland
 
 278.1
Larval Trachea
 
 247.825
Larval Carcass
 
 229.825
Adult Head
 
 387
Adult Eye
 
 453.85
Adult Brain
 
 411.1
Adult Thoracic-Abdominal Ganglion
 
 384.1
Adult Crop
 
 247.1
Adult Midgut
 (1020)
Adult Hindgut
 
 338.2
Adult Malpighian Tubules
 
 460.2
Adult Fat Body
 
 360.8
Adult Salivary Gland
 
 266.6
Adult Heart
 528.025
Adult VirginFemale Spermatheca
 (547.3)
Adult InseminatedFemale Spermatheca
 
 493.5
Adult Ovary
 
 311.1
Adult Testis
 
 88.3
Adult Male Accessory Gland
 
 300.2
Adult Carcass
 
 340.7
Expression Level Scale
 None 
 Low 
 Moderate 
 High 
Linear, scaled to High level expression
Tissue   Expression Level
Larval Central Nervous System
 
 366.65
Larval Midgut
 
 739.7
Larval Hindgut
 
 246.9
Larval Malpighian Tubules
 
 592.3
Larval Fat Body
 
 607.4
Larval Salivary Gland
 
 278.1
Larval Trachea
 
 247.825
Larval Carcass
 
 229.825
Adult Head
 
 387
Adult Eye
 
 453.85
Adult Brain
 
 411.1
Adult Thoracic-Abdominal Ganglion
 
 384.1
Adult Crop
 
 247.1
Adult Midgut
 1020
Adult Hindgut
 
 338.2
Adult Malpighian Tubules
 
 460.2
Adult Fat Body
 
 360.8
Adult Salivary Gland
 
 266.6
Adult Heart
 
 528.025
Adult VirginFemale Spermatheca
 
 547.3
Adult InseminatedFemale Spermatheca
 
 493.5
Adult Ovary
 
 311.1
Adult Testis
 
 88.3
Adult Male Accessory Gland
 
 300.2
Adult Carcass
 
 340.7
Expression Level Scale
 None 
 Low 
 Moderate 
 High 
 Very high 
Linear, scaled to Very high expression
Tissue   Expression Level
Larval Central Nervous System
 
 366.65
Larval Midgut
 
 739.7
Larval Hindgut
 
 246.9
Larval Malpighian Tubules
 
 592.3
Larval Fat Body
 
 607.4
Larval Salivary Gland
 
 278.1
Larval Trachea
 
 247.825
Larval Carcass
 
 229.825
Adult Head
 
 387
Adult Eye
 
 453.85
Adult Brain
 
 411.1
Adult Thoracic-Abdominal Ganglion
 
 384.1
Adult Crop
 
 247.1
Adult Midgut
 
 1020
Adult Hindgut
 
 338.2
Adult Malpighian Tubules
 
 460.2
Adult Fat Body
 
 360.8
Adult Salivary Gland
 
 266.6
Adult Heart
 
 528.025
Adult VirginFemale Spermatheca
 
 547.3
Adult InseminatedFemale Spermatheca
 
 493.5
Adult Ovary
 
 311.1
Adult Testis
 
 88.3
Adult Male Accessory Gland
 
 300.2
Adult Carcass
 
 340.7
Expression Level Scale
 None 
 Low 
 Moderate 
 High 
 Very high 
log, scaled to maximum FBgn0036813 expression level
Tissue   Expression Level
Larval Central Nervous System
 
 366.65
Larval Midgut
 
 739.7
Larval Hindgut
 
 246.9
Larval Malpighian Tubules
 
 592.3
Larval Fat Body
 
 607.4
Larval Salivary Gland
 
 278.1
Larval Trachea
 
 247.825
Larval Carcass
 
 229.825
Adult Head
 
 387
Adult Eye
 
 453.85
Adult Brain
 
 411.1
Adult Thoracic-Abdominal Ganglion
 
 384.1
Adult Crop
 
 247.1
Adult Midgut
 
 1020
Adult Hindgut
 
 338.2
Adult Malpighian Tubules
 
 460.2
Adult Fat Body
 
 360.8
Adult Salivary Gland
 
 266.6
Adult Heart
 
 528.025
Adult VirginFemale Spermatheca
 
 547.3
Adult InseminatedFemale Spermatheca
 
 493.5
Adult Ovary
 
 311.1
Adult Testis
 
 88.3
Adult Male Accessory Gland
 
 300.2
Adult Carcass
 
 340.7
Expression Level Scale
 None 
 Low 
 Moderate 
 High 
 Very high 
log, scaled to Moderate expression
Tissue   Expression Level
Larval Central Nervous System
 
 366.65
Larval Midgut
 739.7
Larval Hindgut
 
 246.9
Larval Malpighian Tubules
 592.3
Larval Fat Body
 607.4
Larval Salivary Gland
 
 278.1
Larval Trachea
 
 247.825
Larval Carcass
 
 229.825
Adult Head
 
 387
Adult Eye
 
 453.85
Adult Brain
 
 411.1
Adult Thoracic-Abdominal Ganglion
 
 384.1
Adult Crop
 
 247.1
Adult Midgut
 (1020)
Adult Hindgut
 
 338.2
Adult Malpighian Tubules
 
 460.2
Adult Fat Body
 
 360.8
Adult Salivary Gland
 
 266.6
Adult Heart
 528.025
Adult VirginFemale Spermatheca
 547.3
Adult InseminatedFemale Spermatheca
 
 493.5
Adult Ovary
 
 311.1
Adult Testis
 
 88.3
Adult Male Accessory Gland
 
 300.2
Adult Carcass
 
 340.7
Expression Level Scale
 None 
 Low 
 Moderate 
 High 
log, scaled to High level expression
Tissue   Expression Level
Larval Central Nervous System
 
 366.65
Larval Midgut
 
 739.7
Larval Hindgut
 
 246.9
Larval Malpighian Tubules
 
 592.3
Larval Fat Body
 
 607.4
Larval Salivary Gland
 
 278.1
Larval Trachea
 
 247.825
Larval Carcass
 
 229.825
Adult Head
 
 387
Adult Eye
 
 453.85
Adult Brain
 
 411.1
Adult Thoracic-Abdominal Ganglion
 
 384.1
Adult Crop
 
 247.1
Adult Midgut
 1020
Adult Hindgut
 
 338.2
Adult Malpighian Tubules
 
 460.2
Adult Fat Body
 
 360.8
Adult Salivary Gland
 
 266.6
Adult Heart
 
 528.025
Adult VirginFemale Spermatheca
 
 547.3
Adult InseminatedFemale Spermatheca
 
 493.5
Adult Ovary
 
 311.1
Adult Testis
 
 88.3
Adult Male Accessory Gland
 
 300.2
Adult Carcass
 
 340.7
Expression Level Scale
 None 
 Low 
 Moderate 
 High 
 Very high 
log, scaled to Very high expression
Tissue   Expression Level
Larval Central Nervous System
 
 366.65
Larval Midgut
 
 739.7
Larval Hindgut
 
 246.9
Larval Malpighian Tubules
 
 592.3
Larval Fat Body
 
 607.4
Larval Salivary Gland
 
 278.1
Larval Trachea
 
 247.825
Larval Carcass
 
 229.825
Adult Head
 
 387
Adult Eye
 
 453.85
Adult Brain
 
 411.1
Adult Thoracic-Abdominal Ganglion
 
 384.1
Adult Crop
 
 247.1
Adult Midgut
 
 1020
Adult Hindgut
 
 338.2
Adult Malpighian Tubules
 
 460.2
Adult Fat Body
 
 360.8
Adult Salivary Gland
 
 266.6
Adult Heart
 
 528.025
Adult VirginFemale Spermatheca
 
 547.3
Adult InseminatedFemale Spermatheca
 
 493.5
Adult Ovary
 
 311.1
Adult Testis
 
 88.3
Adult Male Accessory Gland
 
 300.2
Adult Carcass
 
 340.7
Expression Level Scale
 None 
 Low 
 Moderate 
 High 
 Very high 
Heatmap
Tissue   Expression Level
Larval Central Nervous System
 
 
Larval Midgut
 
 
Larval Hindgut
 
 
Larval Malpighian Tubules
 
 
Larval Fat Body
 
 
Larval Salivary Gland
 
 
Larval Trachea
 
 
Larval Carcass
 
 
Adult Head
 
 
Adult Eye
 
 
Adult Brain
 
 
Adult Thoracic-Abdominal Ganglion
 
 
Adult Crop
 
 
Adult Midgut
 
 
Adult Hindgut
 
 
Adult Malpighian Tubules
 
 
Adult Fat Body
 
 
Adult Salivary Gland
 
 
Adult Heart
 
 
Adult VirginFemale Spermatheca
 
 
Adult InseminatedFemale Spermatheca
 
 
Adult Ovary
 
 
Adult Testis
 
 
Adult Male Accessory Gland
 
 
Adult Carcass
 
 

FlyAtlas Organ/Tissue Expression, larval vs. adult
Larval Expression Level Tissue Adult Expression Level
 
NA 
Head
 
 387
 
NA 
Eye
 
 453.85
 
NA 
Brain
 
 411.1
 
366.65 
Central Nervous System
 
 NA
 
NA 
Thoracic-Abdominal Ganglion
 
 384.1
 
NA 
Crop
 
 247.1
 
739.7 
Midgut
 
 1020
 
246.9 
Hindgut
 
 338.2
 
592.3 
Malpighian Tubules
 
 460.2
 
607.4 
Fat Body
 
 360.8
 
278.1 
Salivary Gland
 
 266.6
 
NA 
Heart
 
 528.025
 
247.825 
Trachea
 
 NA
 
NA 
VirginFemale Spermatheca
 
 547.3
 
NA 
InseminatedFemale Spermatheca
 
 493.5
 
NA 
Ovary
 
 311.1
 
NA 
Testis
 
 88.3
 
NA 
Male Accessory Gland
 
 300.2
 
229.825 
Carcass
 
 340.7

modENCODE Temporal Expression Data (Graveley et al., 2011)
FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
hide Expression Clusters
hide External Data & Images
Linkouts
FLIGHT - Cell culture data for RNAi and other high-throughput technologies
FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
FlyExpress - Embryonic expression images (BDGP data)
hide Alleles & Phenotypes
hide Summary of Allele Phenotypes
Lethality
Allele
Sterility
Allele
Phenotype manifest in
Allele
hide Classical Alleles ( 3 )
For All Classical Alleles Show

Allele of Aut1ClassMutagenStocksKnown lesion
Aut1c031801 --
Aut1EY083961 Yes
Aut1100 Yes
hide Alleles Carried on Transgenic Constructs ( 5 )
For All Alleles Carried on Transgenic Constructs Show

Allele of Aut1ClassMutagenStocksKnown lesion
Aut1GD120641 Yes
Aut1HMS013481 Yes
Aut1KK1086661 Yes
Aut1dsRNA.Scer\UAS0 Yes
Aut1Scer\UAS.cJa0 Yes
hide Aneuploid Aberrations
Partially disrupted in
hide Transgenic Constructs & Insertions
Transgenic Constructs
Type of construct
Name
Expression data
Insertions
Type of insertions
Name
Expression data
insertion of mobile activating element
miscellaneous insertions
hide Gene Ontology: Function, Process & Cellular Component ( 1 unique term )
hide Terms Based on Experimental Evidence ( 1 term )
Molecular Function ( 0 terms)
Biological Process
CV term
References
inferred from mutant phenotype
Cellular Component ( 0 terms)
hide Terms Based on Predictions or Assertions ( 0 terms )
hide Sequence Ontology: Class of Gene
hide Interactions & Pathways
hide Summary of Physical Interactions
Protein-protein
Interacting group
Assay
References
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Interacts with
Please look at the allele data for full details of the genetic interactions
Aut1 allele
Gene
References
hide External Data
Linkouts
DroID - A comprehensive database of gene and protein interactions.
InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets.
hide Orthologs
Genome-wide drosophilid orthologs
Curated drosophilid orthologs
Linkouts
InParanoid A subset of ortholog calls from InParanoid.
OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs.
hide Stocks & Reagents
hide Stocks Listed in FlyBase ( 5 )
Bloomington
Harvard
VDRC
hide Genomic Clones ( 2 )
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
hide cDNA Clones ( 159 )
Please Note
This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones
Other clones
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Linkouts
DRSC - Results from RNAi screens.
GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents
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Source for database identity of
Source for identity of: Aut1 CG6877
Source for database merge of
Additional comments
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Sequence Crossreferences
RefSeq (Transcripts)
RefSeq (Proteins)
Entrez Gene - A searchable database of RefSeq genes.
Other Crossreferences
InterPro domains - A database of protein families, domains, and functional sites
Linkouts
DroID - A comprehensive database of gene and protein interactions.
DRSC - Results from RNAi screens.
FLIGHT - Cell culture data for RNAi and other high-throughput technologies
FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans
GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents
InParanoid A subset of ortholog calls from InParanoid.
InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets.
modMine - Data generated by the modENCODE project.
OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs.
hide Synonyms & Secondary IDs ( 6 )
Reported As
Symbol Synonym
Name Synonym
Aut1
 
Autophagy-specific gene 3
Secondary FlyBase IDs
hide References ( 14 )
Research paper
Kim et al., 2010, BMC Cell Biol. 11: 9
A genetic screen for modifiers of Drosophila caspase Dcp-1 reveals caspase involvement in autophagy and novel caspase-related genes. [FBrf0209948]
Juhasz et al., 2003, FEBS Lett. 543(1-3): 154--158
The Drosophila homolog of Aut1 is essential for autophagy and development. [FBrf0159857]
Supplementary material
Mummery-Widmer et al., 2009, Nature 458(7241):
Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518]
Scott et al., 2007, Curr. Biol. 17(1):
Supplemental Data. [FBrf0208086]
Scott et al., 2004, Dev. Cell 7(2):
Supplementary material. [FBrf0183440]
Personal communication to FlyBase
Ni et al., 2010.12.1, A genome-scale shRNA resource for transgenic RNAi in Drosophila.
A genome-scale shRNA resource for transgenic RNAi in Drosophila. [FBrf0212437]
Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center
RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510]
Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center
RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327]
Abstract
Kadandale and Kiger, 2008, A. Dros. Res. Conf. 49: 61
Eating yourcellf into shape: Atg1 and autophagy in cell shape changes. [FBrf0203489]
Juhasz et al., 2001, Europ. Dros. Res. Conf. 17: H10
Draut1 is essential for macroautophagy and for postembryonal development in Drosophila melanogaster. [FBrf0138034]
Computer file
Gene Disruption Project members and Exelixis, 2005, Genomic mapping of Exelixis insertion collection.
Genomic mapping of Exelixis insertion collection. [FBrf0184340]
Gene Disruption Project members, 2001-, [title not yet available]
[title not yet available] [FBrf0132177]
BDGP Project Members, 2000-, Berkeley Drosophila Genome Project.
Berkeley Drosophila Genome Project. [FBrf0125078]