• Home
• Tools
  • Tools Overview
  • Query Tools

    
    • QuickSearch
    • QueryBuilder
    • TermLink
    • CytoSearch
    • RNA-Seq Search
    • Interactions Browser
    • ImageBrowse
    • Find A Person
    • Google™ FlyBase
  • Genomic/Map Tools

    
    • BLAST
    • GBrowse
    • GBrowse 2 Beta
    • CytoSearch
    • Feature Mapper
    • Aberrations Maps
    • Chromosome Maps
    • Coordinates Converter
  • Retrieve/Convert

    
    • Batch Download
    • Coordinates Converter
    • ID Converter
  • Data Submission

    
    • Fast-Track Your Paper
    • Submit Personal Comm
    • Add A New Person
    • Update Person Info
  • People

    
    • Find A Person
    • Add A New Person
    • Update Person Info
• Files
  • Files Overview
  • Current release
  • Archived releases
  • Map Conversion
  • FTP site:
  • Releases (FTP)
  • Genomes (FTP)
• Species
  • Phylogeny
  • Sequenced Species
  • Synteny Table
  • Color Illustrations
  • Abbreviations
• Documents
  • About FlyBase
  • Reference Manual:
  • Sections
  • Contents
  • Nomenclature
  • Release Notes
• Resources
  • All Resources
  • Model Organisms
  • Stock Collections
  • Vectors & Constructs
  • Other links:
  • BDGP
  • DGRC
  • DIS by issue
  • FlyExpress
  • Interactive Fly
  • modENCODE
  • Textpresso for Fly
• News
  • News
  • FlyBase Forum
  • FlyBase Positions
  • Meetings
  • Courses
  • Fly Board
  • White papers
  • Funding
  • bionet.dros
• Help
  • Google™ FlyBase
  • Site Map
  • FAQs
  • FlyBase Guides
  • Video Tutorials
  • Report help
  • New to Flies
  • Pers. comm.
  • Author guidelines
  • Contact FlyBase
• Archives
  • Prior Release
  • Other Archives
  • Coordinate Converter

Gene Dmel\Indy

General Information
Symbol	Dmel\Indy	Species	D. melanogaster
Name	I'm not dead yet	Annotation symbol	CG3979
Feature type	protein_coding_gene	FlyBase ID	FBgn0036816
Gene Model Status	Current	Stock availability	37 publicly available
Genomic Location
Chromosome (arm)	3L	Recombination map
Cytogenetic map	75E1-75E2	Sequence location	3L:18,821,732..18,839,367 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene I'm not dead yet is referred to in FlyBase by the symbol Dmel\Indy (CG3979, FBgn0036816). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: citrate transmembrane transporter activity; succinate transmembrane transporter activity. There is experimental evidence that it is involved in the biological process: regulation of sequestering of triglyceride; determination of adult lifespan. 51 alleles are reported. No phenotypic data is available. It has 4 annotated transcripts and 4 annotated polypeptides. Protein features are: Sodium/sulphate symporter. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression. Peak expression observed during early pupal stages. Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, adult thoracico-abdominal ganglion, adult crop, larval/adult midgut, larval/adult hindgut, adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult testis, larval/adult carcass. Expression at moderate levels in the following post-embryonic organs or tissues: larval/adult central nervous system, larval Malpighian tubules, adult male accessory gland. Comments on Affy2 ProbeSet: ProbeSet 1641566_s_at completely aligns to an exonic region common to each of the 4 FlyBase-annotated transcript isoforms of Indy. Gene sequence location is 3L:18821732..18839367.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 75E1-75E2   Limits computationally determined from genome sequence between P{PZ}W05014 and P{lacW}l(3)j14E7j14E7
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\Indy for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.46 Transposon inserted in intron
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) Indy-RA FBtr0075083  NM_079426   2484   572 Indy-RB FBtr0075081  NM_168778   2572   590 Indy-RC FBtr0075082  NM_168779   2600   572 Indy-RD FBtr0301857  NM_001169994   2581   572
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein Indy-PA   FBpp0074850   63.6   572   8.55     NP_524150   AAF49226 Indy-PB   FBpp0074848   65.6   590   8.55     NP_730363   AAF49227 Indy-PC   FBpp0074849   63.6   572   8.55     NP_730364   AAN11670 Indy-PD   FBpp0291071   63.6   572   8.55     NP_001163465   ACZ94736
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Sodium/sulphate symporter (IPR001898)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA433278   AA441327   AA567789   AA820509   AA941876   AA949163   AE014296 AAF49226   AE014296 AAF49227   AE014296 AAN11670   AE014296 ACZ94736   AF217399 AAF73384   AF509505 AAN86815   AI258115   AI258921   AI260815   AI455443   AI517060   AI946002   AQ025236   AQ073949   AX094175   AX260108   AX662047 CAD79974   AY102686 AAM27515   BF488845   BF491985   BF492040   BI168723   BI168799   BI169304   BI169923   BI171748   BI172665   BI215071   BI216538   BI216583   BI231367   BI232372   BI232894   BI234172   BI237335   BI239128   BI242037   BI243795   BI357208   BI357831   BI357886   BI357928   BI358486   BI361776   BI364780   BI365145   BI367492   BI367562   BI369528   BI369891   BI369906   BI370428   BI375610   BI375664   BI484290   BI485172   BI486833   BI578236   BT100230   BZ665552   CA803667   CK657829   CK660288   CL705880   CO186480   CO190382   CO268367   CO270202   CO273271   CO273290   CO274266   CO278026   CO279408   CO285387   CO286097   CO287801   CO288264   CO297741   CO301457   CO307382   CO312942   CO315334   CO320343   CO326229   CO326282   CO328689   CO330823   CO341805   CO342196   CO345325   CW848236   CZ466485   CZ468151   CZ468153   CZ469042   CZ469208   CZ469440   CZ470635   CZ474165   CZ474166   CZ474602   CZ475682   CZ475972   CZ477308   CZ481837   CZ483551   DN154349   EC051122   EC058749   EC061089   EC062371   EC062768   EC067193   EC067552   EC070631   EC071941   EC071943   EC081283   EC083376   EC087200   EC196718   EC203639   EC206335   EC206959   EC209949   EC213903   EC219912   EC227943   EC230533   EC234718   EC236632   EC244108   EC247900   EC258331   ES689471   EV578736   EV582728   EV585993   EV587808   EV591139   EV595347   GH748953   GH749690   GH749892   GH751423   GH751475   GH752260   GH753322   GH753769   GH756475   GH756489   GH756535   GH757029   GH757635   GH759435   GH760785   GH771338   GH776874   GH778110   GH781958   GH782838   GH784310   GH786368   GH787879   GH790639   GH790893   GH793395   GH793421   GH793492   GH793588   GH795658   GH795827   GH796041   GH796674   GH799428   GH800276   GH802380   GH803450   GH805568   GH807782   GH808357   GH808993   GH809306   GH809526   GH810427   GH810543   GH810696   GH811380   GH813586   GH814879   GH817357   GH819308   GH820378   GH824717   GH824749   GH825347   GH826418   GH827592   GH828374   GH828502   GH830826   GH831326   GH834197   GH836675   GH839203   GH839433   GH839805   GH840956   GH842733   GH844643   GH846605   GH849202   GH850581   GH852444   GH853649   GH856938   GH857899   GH858099   GH859046   GH859284   GH860304   GH861058   GH863016   GH864364   GH864623   GH867867   GH867968   GH869639   GH871864   GH872274   GH876897   GH881180   GH883903   GH885686   GH892407   GH892558   GH892777   GH893172   GH893245   GH893905   GH894297   GH895609   GH896264   GH897332   GH898062   GH901671   GH902876   GH904007   GH909375   GH909485   GH912734   GH913308   GH916748   GH916959   GH916977   GH917703   GH918531   GH918556   GH918970   GH919204   GH921503   GH922185   GH922397   GH923270   GH923285   GH923744   GH926908   GH928353   GH929408   GH930774   GH930907   GH931564   GH932156   GH932671   GH933379   GH933870   GH935146   GH936067   GH936898   GH937729
UniProtKB/Swiss-Prot	Q9VVT2
UniProtKB/TrEMBL	E1JI19
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
in situ Stage Tissue/Position (including subcellular localization) Reference embryonic stage 1 -- 3   organism   (Fisher et al., 2012) Comment:maternally deposited embryonic stage 4 -- 6   organism | faint & ubiquitous   • cytoplasm | basal (Fisher et al., 2012) Comment:apically cleared embryonic stage 7 -- 8   organism | faint & ubiquitous   (Fisher et al., 2012) pole cell   (Fisher et al., 2012) embryonic stage 9 -- 10   organism | faint & ubiquitous   (Fisher et al., 2012) embryonic stage 11 -- 12   anterior midgut primordium   (Fisher et al., 2012) hindgut proper primordium   (Fisher et al., 2012) posterior midgut primordium   (Fisher et al., 2012) trunk mesoderm   (Fisher et al., 2012) yolk nucleus   (Fisher et al., 2012) embryonic stage 13 -- 16   embryonic/larval midgut   (Fisher et al., 2012)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
mass spectroscopy Stage Tissue/Position (including subcellular localization) Reference day 7 of adulthood -- day 49 of adulthood   adult heart   (Cammarato et al., 2011)
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
plasma membrane inferred from direct assay (Knauf et al., 2002, Khanna et al., 2010)
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, adult thoracico-abdominal ganglion, adult crop, larval/adult midgut, larval/adult hindgut, adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult testis, larval/adult carcass. Expression at moderate levels in the following post-embryonic organs or tissues: larval/adult central nervous system, larval Malpighian tubules, adult male accessory gland. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    288.85 Larval Midgut    1028.1 Larval Hindgut    1268 Larval Malpighian Tubules    341.4 Larval Fat Body    2519.8 Larval Salivary Gland    589.9 Larval Trachea    1096.075 Larval Carcass    1394.075 Adult Head    1036.5 Adult Eye    939.9 Adult Brain    404 Adult Thoracic-Abdominal Ganglion    612.2 Adult Crop    2686.3 Adult Midgut    1231.2 Adult Hindgut    1398.8 Adult Malpighian Tubules    1008.8 Adult Fat Body    4585 Adult Salivary Gland    3809.2 Adult Heart    3966.4 Adult VirginFemale Spermatheca    3346.8 Adult InseminatedFemale Spermatheca    2879.9 Adult Ovary    922.4 Adult Testis    628.5 Adult Male Accessory Gland    254.1 Adult Carcass    2207.6 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    288.85 Larval Midgut  (1028.1) Larval Hindgut  (1268) Larval Malpighian Tubules    341.4 Larval Fat Body  (2519.8) Larval Salivary Gland  (589.9) Larval Trachea  (1096.075) Larval Carcass  (1394.075) Adult Head  (1036.5) Adult Eye  (939.9) Adult Brain    404 Adult Thoracic-Abdominal Ganglion  (612.2) Adult Crop  (2686.3) Adult Midgut  (1231.2) Adult Hindgut  (1398.8) Adult Malpighian Tubules  (1008.8) Adult Fat Body  (4585) Adult Salivary Gland  (3809.2) Adult Heart  (3966.4) Adult VirginFemale Spermatheca  (3346.8) Adult InseminatedFemale Spermatheca  (2879.9) Adult Ovary  (922.4) Adult Testis  (628.5) Adult Male Accessory Gland    254.1 Adult Carcass  (2207.6) Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    288.85 Larval Midgut  1028.1 Larval Hindgut  (1268) Larval Malpighian Tubules    341.4 Larval Fat Body  (2519.8) Larval Salivary Gland    589.9 Larval Trachea  (1096.075) Larval Carcass  (1394.075) Adult Head  1036.5 Adult Eye    939.9 Adult Brain    404 Adult Thoracic-Abdominal Ganglion    612.2 Adult Crop  (2686.3) Adult Midgut  (1231.2) Adult Hindgut  (1398.8) Adult Malpighian Tubules  1008.8 Adult Fat Body  (4585) Adult Salivary Gland  (3809.2) Adult Heart  (3966.4) Adult VirginFemale Spermatheca  (3346.8) Adult InseminatedFemale Spermatheca  (2879.9) Adult Ovary    922.4 Adult Testis    628.5 Adult Male Accessory Gland    254.1 Adult Carcass  (2207.6) Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    288.85 Larval Midgut    1028.1 Larval Hindgut    1268 Larval Malpighian Tubules    341.4 Larval Fat Body    2519.8 Larval Salivary Gland    589.9 Larval Trachea    1096.075 Larval Carcass    1394.075 Adult Head    1036.5 Adult Eye    939.9 Adult Brain    404 Adult Thoracic-Abdominal Ganglion    612.2 Adult Crop    2686.3 Adult Midgut    1231.2 Adult Hindgut    1398.8 Adult Malpighian Tubules    1008.8 Adult Fat Body    4585 Adult Salivary Gland    3809.2 Adult Heart    3966.4 Adult VirginFemale Spermatheca    3346.8 Adult InseminatedFemale Spermatheca    2879.9 Adult Ovary    922.4 Adult Testis    628.5 Adult Male Accessory Gland    254.1 Adult Carcass    2207.6 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    288.85 Larval Midgut    1028.1 Larval Hindgut    1268 Larval Malpighian Tubules    341.4 Larval Fat Body    2519.8 Larval Salivary Gland    589.9 Larval Trachea    1096.075 Larval Carcass    1394.075 Adult Head    1036.5 Adult Eye    939.9 Adult Brain    404 Adult Thoracic-Abdominal Ganglion    612.2 Adult Crop    2686.3 Adult Midgut    1231.2 Adult Hindgut    1398.8 Adult Malpighian Tubules    1008.8 Adult Fat Body    4585 Adult Salivary Gland    3809.2 Adult Heart    3966.4 Adult VirginFemale Spermatheca    3346.8 Adult InseminatedFemale Spermatheca    2879.9 Adult Ovary    922.4 Adult Testis    628.5 Adult Male Accessory Gland    254.1 Adult Carcass    2207.6 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    288.85 Larval Midgut  (1028.1) Larval Hindgut  (1268) Larval Malpighian Tubules    341.4 Larval Fat Body  (2519.8) Larval Salivary Gland  589.9 Larval Trachea  (1096.075) Larval Carcass  (1394.075) Adult Head  (1036.5) Adult Eye  (939.9) Adult Brain    404 Adult Thoracic-Abdominal Ganglion  612.2 Adult Crop  (2686.3) Adult Midgut  (1231.2) Adult Hindgut  (1398.8) Adult Malpighian Tubules  (1008.8) Adult Fat Body  (4585) Adult Salivary Gland  (3809.2) Adult Heart  (3966.4) Adult VirginFemale Spermatheca  (3346.8) Adult InseminatedFemale Spermatheca  (2879.9) Adult Ovary  (922.4) Adult Testis  628.5 Adult Male Accessory Gland    254.1 Adult Carcass  (2207.6) Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    288.85 Larval Midgut  1028.1 Larval Hindgut  1268 Larval Malpighian Tubules    341.4 Larval Fat Body  (2519.8) Larval Salivary Gland    589.9 Larval Trachea  1096.075 Larval Carcass  1394.075 Adult Head  1036.5 Adult Eye    939.9 Adult Brain    404 Adult Thoracic-Abdominal Ganglion    612.2 Adult Crop  (2686.3) Adult Midgut  1231.2 Adult Hindgut  1398.8 Adult Malpighian Tubules  1008.8 Adult Fat Body  (4585) Adult Salivary Gland  (3809.2) Adult Heart  (3966.4) Adult VirginFemale Spermatheca  (3346.8) Adult InseminatedFemale Spermatheca  (2879.9) Adult Ovary    922.4 Adult Testis    628.5 Adult Male Accessory Gland    254.1 Adult Carcass  (2207.6) Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    288.85 Larval Midgut    1028.1 Larval Hindgut    1268 Larval Malpighian Tubules    341.4 Larval Fat Body    2519.8 Larval Salivary Gland    589.9 Larval Trachea    1096.075 Larval Carcass    1394.075 Adult Head    1036.5 Adult Eye    939.9 Adult Brain    404 Adult Thoracic-Abdominal Ganglion    612.2 Adult Crop    2686.3 Adult Midgut    1231.2 Adult Hindgut    1398.8 Adult Malpighian Tubules    1008.8 Adult Fat Body    4585 Adult Salivary Gland    3809.2 Adult Heart    3966.4 Adult VirginFemale Spermatheca    3346.8 Adult InseminatedFemale Spermatheca    2879.9 Adult Ovary    922.4 Adult Testis    628.5 Adult Male Accessory Gland    254.1 Adult Carcass    2207.6 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    1036.5   NA  Eye    939.9   NA  Brain    404   288.85  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    612.2   NA  Crop    2686.3   1028.1  Midgut    1231.2   1268  Hindgut    1398.8   341.4  Malpighian Tubules    1008.8   2519.8  Fat Body    4585   589.9  Salivary Gland    3809.2   NA  Heart    3966.4   1096.075  Trachea    NA   NA  VirginFemale Spermatheca    3346.8   NA  InseminatedFemale Spermatheca    2879.9   NA  Ovary    922.4   NA  Testis    628.5   NA  Male Accessory Gland    254.1   1394.075  Carcass    2207.6 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    17 central nervous system, larvae L3    13 central nervous system, pupae P8    9 head, virgin 1-day female    33 head, virgin 4-day female    28 head, virgin 20-day female    66 head, mated 1-day female    23 head, mated 4-day female    37 head, mated 20-day female    53 head, mated 1-day male    34 head, mated 4-day male    34 head, mated 20-day male    61 salivary gland, larvae L3 wandering    3 salivary gland, white prepupae    38 digestive system, larvae L3 wandering    15 digestive system, 1-day adult    36 digestive system, 4-day adult    30 digestive system, 20-day adult    39 fat body, larvae L3 wandering    68 fat body, white prepupae    82 fat body, pupae P8    22 carcass, larvae L3 wandering    48 carcass, 1-day adult    50 carcass, 4-day adult    59 carcass, 20-day adult    65 ovary, virgin 4-day female    68 ovary, mated 4-day female    49 testis, mated 4-day male    18 accessory gland, mated 4-day male    8 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    17 central nervous system, larvae L3    13 central nervous system, pupae P8    9 head, virgin 1-day female  (33) head, virgin 4-day female  (28) head, virgin 20-day female  (66) head, mated 1-day female    23 head, mated 4-day female  (37) head, mated 20-day female  (53) head, mated 1-day male  (34) head, mated 4-day male  (34) head, mated 20-day male  (61) salivary gland, larvae L3 wandering    3 salivary gland, white prepupae  (38) digestive system, larvae L3 wandering    15 digestive system, 1-day adult  (36) digestive system, 4-day adult  (30) digestive system, 20-day adult  (39) fat body, larvae L3 wandering  (68) fat body, white prepupae  (82) fat body, pupae P8    22 carcass, larvae L3 wandering  (48) carcass, 1-day adult  (50) carcass, 4-day adult  (59) carcass, 20-day adult  (65) ovary, virgin 4-day female  (68) ovary, mated 4-day female  (49) testis, mated 4-day male    18 accessory gland, mated 4-day male    8 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    17 central nervous system, larvae L3    13 central nervous system, pupae P8    9 head, virgin 1-day female    33 head, virgin 4-day female    28 head, virgin 20-day female    66 head, mated 1-day female    23 head, mated 4-day female    37 head, mated 20-day female    53 head, mated 1-day male    34 head, mated 4-day male    34 head, mated 20-day male    61 salivary gland, larvae L3 wandering    3 salivary gland, white prepupae    38 digestive system, larvae L3 wandering    15 digestive system, 1-day adult    36 digestive system, 4-day adult    30 digestive system, 20-day adult    39 fat body, larvae L3 wandering    68 fat body, white prepupae    82 fat body, pupae P8    22 carcass, larvae L3 wandering    48 carcass, 1-day adult    50 carcass, 4-day adult    59 carcass, 20-day adult    65 ovary, virgin 4-day female    68 ovary, mated 4-day female    49 testis, mated 4-day male    18 accessory gland, mated 4-day male    8 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    17 central nervous system, larvae L3    13 central nervous system, pupae P8    9 head, virgin 1-day female    33 head, virgin 4-day female    28 head, virgin 20-day female    66 head, mated 1-day female    23 head, mated 4-day female    37 head, mated 20-day female    53 head, mated 1-day male    34 head, mated 4-day male    34 head, mated 20-day male    61 salivary gland, larvae L3 wandering    3 salivary gland, white prepupae    38 digestive system, larvae L3 wandering    15 digestive system, 1-day adult    36 digestive system, 4-day adult    30 digestive system, 20-day adult    39 fat body, larvae L3 wandering    68 fat body, white prepupae    82 fat body, pupae P8    22 carcass, larvae L3 wandering    48 carcass, 1-day adult    50 carcass, 4-day adult    59 carcass, 20-day adult    65 ovary, virgin 4-day female    68 ovary, mated 4-day female    49 testis, mated 4-day male    18 accessory gland, mated 4-day male    8 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    17 central nervous system, larvae L3    13 central nervous system, pupae P8    9 head, virgin 1-day female    33 head, virgin 4-day female    28 head, virgin 20-day female    66 head, mated 1-day female    23 head, mated 4-day female    37 head, mated 20-day female    53 head, mated 1-day male    34 head, mated 4-day male    34 head, mated 20-day male    61 salivary gland, larvae L3 wandering    3 salivary gland, white prepupae    38 digestive system, larvae L3 wandering    15 digestive system, 1-day adult    36 digestive system, 4-day adult    30 digestive system, 20-day adult    39 fat body, larvae L3 wandering    68 fat body, white prepupae    82 fat body, pupae P8    22 carcass, larvae L3 wandering    48 carcass, 1-day adult    50 carcass, 4-day adult    59 carcass, 20-day adult    65 ovary, virgin 4-day female    68 ovary, mated 4-day female    49 testis, mated 4-day male    18 accessory gland, mated 4-day male    8 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    17 central nervous system, larvae L3    13 central nervous system, pupae P8    9 head, virgin 1-day female  (33) head, virgin 4-day female  28 head, virgin 20-day female  (66) head, mated 1-day female    23 head, mated 4-day female  (37) head, mated 20-day female  (53) head, mated 1-day male  (34) head, mated 4-day male  (34) head, mated 20-day male  (61) salivary gland, larvae L3 wandering    3 salivary gland, white prepupae  (38) digestive system, larvae L3 wandering    15 digestive system, 1-day adult  (36) digestive system, 4-day adult  30 digestive system, 20-day adult  (39) fat body, larvae L3 wandering  (68) fat body, white prepupae  (82) fat body, pupae P8    22 carcass, larvae L3 wandering  (48) carcass, 1-day adult  (50) carcass, 4-day adult  (59) carcass, 20-day adult  (65) ovary, virgin 4-day female  (68) ovary, mated 4-day female  (49) testis, mated 4-day male    18 accessory gland, mated 4-day male    8 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    17 central nervous system, larvae L3    13 central nervous system, pupae P8    9 head, virgin 1-day female    33 head, virgin 4-day female    28 head, virgin 20-day female    66 head, mated 1-day female    23 head, mated 4-day female    37 head, mated 20-day female    53 head, mated 1-day male    34 head, mated 4-day male    34 head, mated 20-day male    61 salivary gland, larvae L3 wandering    3 salivary gland, white prepupae    38 digestive system, larvae L3 wandering    15 digestive system, 1-day adult    36 digestive system, 4-day adult    30 digestive system, 20-day adult    39 fat body, larvae L3 wandering    68 fat body, white prepupae    82 fat body, pupae P8    22 carcass, larvae L3 wandering    48 carcass, 1-day adult    50 carcass, 4-day adult    59 carcass, 20-day adult    65 ovary, virgin 4-day female    68 ovary, mated 4-day female    49 testis, mated 4-day male    18 accessory gland, mated 4-day male    8 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    17 central nervous system, larvae L3    13 central nervous system, pupae P8    9 head, virgin 1-day female    33 head, virgin 4-day female    28 head, virgin 20-day female    66 head, mated 1-day female    23 head, mated 4-day female    37 head, mated 20-day female    53 head, mated 1-day male    34 head, mated 4-day male    34 head, mated 20-day male    61 salivary gland, larvae L3 wandering    3 salivary gland, white prepupae    38 digestive system, larvae L3 wandering    15 digestive system, 1-day adult    36 digestive system, 4-day adult    30 digestive system, 20-day adult    39 fat body, larvae L3 wandering    68 fat body, white prepupae    82 fat body, pupae P8    22 carcass, larvae L3 wandering    48 carcass, 1-day adult    50 carcass, 4-day adult    59 carcass, 20-day adult    65 ovary, virgin 4-day female    68 ovary, mated 4-day female    49 testis, mated 4-day male    18 accessory gland, mated 4-day male    8 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression. Peak expression observed during early pupal stages. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    55 embryo 02-04hr    51 embryo 04-06hr    64 embryo 06-08hr    99 embryo 08-10hr    94 embryo 10-12hr    61 embryo 12-14hr    51 embryo 14-16hr    43 embryo 16-18hr    51 embryo 18-20hr    72 embryo 20-22hr    108 embryo 22-24hr    122 larva L1    79 larva L2    73 larva L3 12hr old    90 larva L3 puffstage 1-2    54 larva L3 puffstage 3-6    40 larva L3 puffstage 7-9    54 white prepupae new    159 white prepupae 12hr    66 white prepupae 24hr    48 pupae 2d postWPP    51 pupae 3d postWPP    36 pupae 4d postWPP    45 adult male 01day    60 adult male 05day    52 adult male 30day    42 adult female 01day    62 adult female 05day    59 adult female 30day    53 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (55) embryo 02-04hr  (51) embryo 04-06hr  (64) embryo 06-08hr  (99) embryo 08-10hr  (94) embryo 10-12hr  (61) embryo 12-14hr  (51) embryo 14-16hr  (43) embryo 16-18hr  (51) embryo 18-20hr  (72) embryo 20-22hr  (108) embryo 22-24hr  (122) larva L1  (79) larva L2  (73) larva L3 12hr old  (90) larva L3 puffstage 1-2  (54) larva L3 puffstage 3-6  (40) larva L3 puffstage 7-9  (54) white prepupae new  (159) white prepupae 12hr  (66) white prepupae 24hr  (48) pupae 2d postWPP  (51) pupae 3d postWPP  (36) pupae 4d postWPP  (45) adult male 01day  (60) adult male 05day  (52) adult male 30day  (42) adult female 01day  (62) adult female 05day  (59) adult female 30day  (53) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    55 embryo 02-04hr    51 embryo 04-06hr    64 embryo 06-08hr    99 embryo 08-10hr    94 embryo 10-12hr    61 embryo 12-14hr    51 embryo 14-16hr    43 embryo 16-18hr    51 embryo 18-20hr    72 embryo 20-22hr  (108) embryo 22-24hr  (122) larva L1    79 larva L2    73 larva L3 12hr old    90 larva L3 puffstage 1-2    54 larva L3 puffstage 3-6    40 larva L3 puffstage 7-9    54 white prepupae new  (159) white prepupae 12hr    66 white prepupae 24hr    48 pupae 2d postWPP    51 pupae 3d postWPP    36 pupae 4d postWPP    45 adult male 01day    60 adult male 05day    52 adult male 30day    42 adult female 01day    62 adult female 05day    59 adult female 30day    53 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    55 embryo 02-04hr    51 embryo 04-06hr    64 embryo 06-08hr    99 embryo 08-10hr    94 embryo 10-12hr    61 embryo 12-14hr    51 embryo 14-16hr    43 embryo 16-18hr    51 embryo 18-20hr    72 embryo 20-22hr    108 embryo 22-24hr    122 larva L1    79 larva L2    73 larva L3 12hr old    90 larva L3 puffstage 1-2    54 larva L3 puffstage 3-6    40 larva L3 puffstage 7-9    54 white prepupae new    159 white prepupae 12hr    66 white prepupae 24hr    48 pupae 2d postWPP    51 pupae 3d postWPP    36 pupae 4d postWPP    45 adult male 01day    60 adult male 05day    52 adult male 30day    42 adult female 01day    62 adult female 05day    59 adult female 30day    53 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    55 embryo 02-04hr    51 embryo 04-06hr    64 embryo 06-08hr    99 embryo 08-10hr    94 embryo 10-12hr    61 embryo 12-14hr    51 embryo 14-16hr    43 embryo 16-18hr    51 embryo 18-20hr    72 embryo 20-22hr    108 embryo 22-24hr    122 larva L1    79 larva L2    73 larva L3 12hr old    90 larva L3 puffstage 1-2    54 larva L3 puffstage 3-6    40 larva L3 puffstage 7-9    54 white prepupae new    159 white prepupae 12hr    66 white prepupae 24hr    48 pupae 2d postWPP    51 pupae 3d postWPP    36 pupae 4d postWPP    45 adult male 01day    60 adult male 05day    52 adult male 30day    42 adult female 01day    62 adult female 05day    59 adult female 30day    53 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (55) embryo 02-04hr  (51) embryo 04-06hr  (64) embryo 06-08hr  (99) embryo 08-10hr  (94) embryo 10-12hr  (61) embryo 12-14hr  (51) embryo 14-16hr  (43) embryo 16-18hr  (51) embryo 18-20hr  (72) embryo 20-22hr  (108) embryo 22-24hr  (122) larva L1  (79) larva L2  (73) larva L3 12hr old  (90) larva L3 puffstage 1-2  (54) larva L3 puffstage 3-6  (40) larva L3 puffstage 7-9  (54) white prepupae new  (159) white prepupae 12hr  (66) white prepupae 24hr  (48) pupae 2d postWPP  (51) pupae 3d postWPP  (36) pupae 4d postWPP  (45) adult male 01day  (60) adult male 05day  (52) adult male 30day  (42) adult female 01day  (62) adult female 05day  (59) adult female 30day  (53) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    55 embryo 02-04hr    51 embryo 04-06hr    64 embryo 06-08hr    99 embryo 08-10hr    94 embryo 10-12hr    61 embryo 12-14hr    51 embryo 14-16hr    43 embryo 16-18hr    51 embryo 18-20hr    72 embryo 20-22hr  108 embryo 22-24hr  122 larva L1    79 larva L2    73 larva L3 12hr old    90 larva L3 puffstage 1-2    54 larva L3 puffstage 3-6    40 larva L3 puffstage 7-9    54 white prepupae new  (159) white prepupae 12hr    66 white prepupae 24hr    48 pupae 2d postWPP    51 pupae 3d postWPP    36 pupae 4d postWPP    45 adult male 01day    60 adult male 05day    52 adult male 30day    42 adult female 01day    62 adult female 05day    59 adult female 30day    53 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    55 embryo 02-04hr    51 embryo 04-06hr    64 embryo 06-08hr    99 embryo 08-10hr    94 embryo 10-12hr    61 embryo 12-14hr    51 embryo 14-16hr    43 embryo 16-18hr    51 embryo 18-20hr    72 embryo 20-22hr    108 embryo 22-24hr    122 larva L1    79 larva L2    73 larva L3 12hr old    90 larva L3 puffstage 1-2    54 larva L3 puffstage 3-6    40 larva L3 puffstage 7-9    54 white prepupae new    159 white prepupae 12hr    66 white prepupae 24hr    48 pupae 2d postWPP    51 pupae 3d postWPP    36 pupae 4d postWPP    45 adult male 01day    60 adult male 05day    52 adult male 30day    42 adult female 01day    62 adult female 05day    59 adult female 30day    53 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    31 Schneider line 2 Sg4    44 embryonic 1182-4H    36 embryonic GM2    97 embryonic Kc167    56 embryonic S1    34 embryonic S3    60 leg disc CME L1    48 wing disc CME-W2    38 wing disc ML-DmD8    37 wing disc ML-DmD9    24 wing disc ML-DmD16-c3    43 wing disc ML-DmD21    27 wing disc ML-DmD32    19 haltere disc ML-DmD17-c3    52 eye-antennal disc ML-DmD11    43 antennal disc ML-DmD20-c5    27 mixed discs ML-DmD4-c1    58 CNS ML-DmBG1-c1    14 CNS ML-DmBG2-c2    28 tumorous blood cells mbn2    123 ovary fGS/OSS    50 ovary OSC    44 ovary OSS    31 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (31) Schneider line 2 Sg4  (44) embryonic 1182-4H  (36) embryonic GM2  (97) embryonic Kc167  (56) embryonic S1  (34) embryonic S3  (60) leg disc CME L1  (48) wing disc CME-W2  (38) wing disc ML-DmD8  (37) wing disc ML-DmD9    24 wing disc ML-DmD16-c3  (43) wing disc ML-DmD21  (27) wing disc ML-DmD32    19 haltere disc ML-DmD17-c3  (52) eye-antennal disc ML-DmD11  (43) antennal disc ML-DmD20-c5  (27) mixed discs ML-DmD4-c1  (58) CNS ML-DmBG1-c1    14 CNS ML-DmBG2-c2  (28) tumorous blood cells mbn2  (123) ovary fGS/OSS  (50) ovary OSC  (44) ovary OSS  (31) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    31 Schneider line 2 Sg4    44 embryonic 1182-4H    36 embryonic GM2    97 embryonic Kc167    56 embryonic S1    34 embryonic S3    60 leg disc CME L1    48 wing disc CME-W2    38 wing disc ML-DmD8    37 wing disc ML-DmD9    24 wing disc ML-DmD16-c3    43 wing disc ML-DmD21    27 wing disc ML-DmD32    19 haltere disc ML-DmD17-c3    52 eye-antennal disc ML-DmD11    43 antennal disc ML-DmD20-c5    27 mixed discs ML-DmD4-c1    58 CNS ML-DmBG1-c1    14 CNS ML-DmBG2-c2    28 tumorous blood cells mbn2  (123) ovary fGS/OSS    50 ovary OSC    44 ovary OSS    31 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    31 Schneider line 2 Sg4    44 embryonic 1182-4H    36 embryonic GM2    97 embryonic Kc167    56 embryonic S1    34 embryonic S3    60 leg disc CME L1    48 wing disc CME-W2    38 wing disc ML-DmD8    37 wing disc ML-DmD9    24 wing disc ML-DmD16-c3    43 wing disc ML-DmD21    27 wing disc ML-DmD32    19 haltere disc ML-DmD17-c3    52 eye-antennal disc ML-DmD11    43 antennal disc ML-DmD20-c5    27 mixed discs ML-DmD4-c1    58 CNS ML-DmBG1-c1    14 CNS ML-DmBG2-c2    28 tumorous blood cells mbn2    123 ovary fGS/OSS    50 ovary OSC    44 ovary OSS    31 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    31 Schneider line 2 Sg4    44 embryonic 1182-4H    36 embryonic GM2    97 embryonic Kc167    56 embryonic S1    34 embryonic S3    60 leg disc CME L1    48 wing disc CME-W2    38 wing disc ML-DmD8    37 wing disc ML-DmD9    24 wing disc ML-DmD16-c3    43 wing disc ML-DmD21    27 wing disc ML-DmD32    19 haltere disc ML-DmD17-c3    52 eye-antennal disc ML-DmD11    43 antennal disc ML-DmD20-c5    27 mixed discs ML-DmD4-c1    58 CNS ML-DmBG1-c1    14 CNS ML-DmBG2-c2    28 tumorous blood cells mbn2    123 ovary fGS/OSS    50 ovary OSC    44 ovary OSS    31 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  31 Schneider line 2 Sg4  (44) embryonic 1182-4H  (36) embryonic GM2  (97) embryonic Kc167  (56) embryonic S1  (34) embryonic S3  (60) leg disc CME L1  (48) wing disc CME-W2  (38) wing disc ML-DmD8  (37) wing disc ML-DmD9    24 wing disc ML-DmD16-c3  (43) wing disc ML-DmD21  27 wing disc ML-DmD32    19 haltere disc ML-DmD17-c3  (52) eye-antennal disc ML-DmD11  (43) antennal disc ML-DmD20-c5  27 mixed discs ML-DmD4-c1  (58) CNS ML-DmBG1-c1    14 CNS ML-DmBG2-c2  28 tumorous blood cells mbn2  (123) ovary fGS/OSS  (50) ovary OSC  (44) ovary OSS  31 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    31 Schneider line 2 Sg4    44 embryonic 1182-4H    36 embryonic GM2    97 embryonic Kc167    56 embryonic S1    34 embryonic S3    60 leg disc CME L1    48 wing disc CME-W2    38 wing disc ML-DmD8    37 wing disc ML-DmD9    24 wing disc ML-DmD16-c3    43 wing disc ML-DmD21    27 wing disc ML-DmD32    19 haltere disc ML-DmD17-c3    52 eye-antennal disc ML-DmD11    43 antennal disc ML-DmD20-c5    27 mixed discs ML-DmD4-c1    58 CNS ML-DmBG1-c1    14 CNS ML-DmBG2-c2    28 tumorous blood cells mbn2  123 ovary fGS/OSS    50 ovary OSC    44 ovary OSS    31 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    31 Schneider line 2 Sg4    44 embryonic 1182-4H    36 embryonic GM2    97 embryonic Kc167    56 embryonic S1    34 embryonic S3    60 leg disc CME L1    48 wing disc CME-W2    38 wing disc ML-DmD8    37 wing disc ML-DmD9    24 wing disc ML-DmD16-c3    43 wing disc ML-DmD21    27 wing disc ML-DmD32    19 haltere disc ML-DmD17-c3    52 eye-antennal disc ML-DmD11    43 antennal disc ML-DmD20-c5    27 mixed discs ML-DmD4-c1    58 CNS ML-DmBG1-c1    14 CNS ML-DmBG2-c2    28 tumorous blood cells mbn2    123 ovary fGS/OSS    50 ovary OSC    44 ovary OSS    31 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    19 cold shock, 4-day adult    12 heat shock, 4-day adult    44 Cadmium 50 mM 6 hrs, larvae L3    44 Cadmium 50 mM 12 hrs, larvae L3    56 Cadmium 50 mM 48 hrs, 4-day adult    57 Cadmium 100 mM 48 hrs, 4-day adult    45 Copper 0.5 mM 12 hrs, larvae L3    21 Copper 15 mM 48 hrs, 4-day adult    27 Zinc 5 mM 12 hrs, larvae L3    25 Zinc 4.5 mM 48 hrs, 4-day adult    30 Ethanol 2.5% 3 hrs, larvae L3    58 Ethanol 5% 3 hrs, larvae L3    52 Ethanol 10% 3 hrs, larvae L3    61 Caffeine 1.5 mg/ml 4 hrs, larvae L3    66 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    48 Caffeine 25 mg/ml 48 hrs, 4-day adult    20 Paraquat 5 mM 48 hrs, 4-day adult    43 Paraquat 10 mM 48 hrs, 4-day adult    67 Rotenone 2 μg 12 hrs, larvae L3    59 Rotenone 8 μg 12 hrs, larvae L3    58 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    19 cold shock, 4-day adult    12 heat shock, 4-day adult  (44) Cadmium 50 mM 6 hrs, larvae L3  (44) Cadmium 50 mM 12 hrs, larvae L3  (56) Cadmium 50 mM 48 hrs, 4-day adult  (57) Cadmium 100 mM 48 hrs, 4-day adult  (45) Copper 0.5 mM 12 hrs, larvae L3    21 Copper 15 mM 48 hrs, 4-day adult  (27) Zinc 5 mM 12 hrs, larvae L3    25 Zinc 4.5 mM 48 hrs, 4-day adult  (30) Ethanol 2.5% 3 hrs, larvae L3  (58) Ethanol 5% 3 hrs, larvae L3  (52) Ethanol 10% 3 hrs, larvae L3  (61) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (66) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (48) Caffeine 25 mg/ml 48 hrs, 4-day adult    20 Paraquat 5 mM 48 hrs, 4-day adult  (43) Paraquat 10 mM 48 hrs, 4-day adult  (67) Rotenone 2 μg 12 hrs, larvae L3  (59) Rotenone 8 μg 12 hrs, larvae L3  (58) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    19 cold shock, 4-day adult    12 heat shock, 4-day adult    44 Cadmium 50 mM 6 hrs, larvae L3    44 Cadmium 50 mM 12 hrs, larvae L3    56 Cadmium 50 mM 48 hrs, 4-day adult    57 Cadmium 100 mM 48 hrs, 4-day adult    45 Copper 0.5 mM 12 hrs, larvae L3    21 Copper 15 mM 48 hrs, 4-day adult    27 Zinc 5 mM 12 hrs, larvae L3    25 Zinc 4.5 mM 48 hrs, 4-day adult    30 Ethanol 2.5% 3 hrs, larvae L3    58 Ethanol 5% 3 hrs, larvae L3    52 Ethanol 10% 3 hrs, larvae L3    61 Caffeine 1.5 mg/ml 4 hrs, larvae L3    66 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    48 Caffeine 25 mg/ml 48 hrs, 4-day adult    20 Paraquat 5 mM 48 hrs, 4-day adult    43 Paraquat 10 mM 48 hrs, 4-day adult    67 Rotenone 2 μg 12 hrs, larvae L3    59 Rotenone 8 μg 12 hrs, larvae L3    58 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    19 cold shock, 4-day adult    12 heat shock, 4-day adult    44 Cadmium 50 mM 6 hrs, larvae L3    44 Cadmium 50 mM 12 hrs, larvae L3    56 Cadmium 50 mM 48 hrs, 4-day adult    57 Cadmium 100 mM 48 hrs, 4-day adult    45 Copper 0.5 mM 12 hrs, larvae L3    21 Copper 15 mM 48 hrs, 4-day adult    27 Zinc 5 mM 12 hrs, larvae L3    25 Zinc 4.5 mM 48 hrs, 4-day adult    30 Ethanol 2.5% 3 hrs, larvae L3    58 Ethanol 5% 3 hrs, larvae L3    52 Ethanol 10% 3 hrs, larvae L3    61 Caffeine 1.5 mg/ml 4 hrs, larvae L3    66 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    48 Caffeine 25 mg/ml 48 hrs, 4-day adult    20 Paraquat 5 mM 48 hrs, 4-day adult    43 Paraquat 10 mM 48 hrs, 4-day adult    67 Rotenone 2 μg 12 hrs, larvae L3    59 Rotenone 8 μg 12 hrs, larvae L3    58 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    19 cold shock, 4-day adult    12 heat shock, 4-day adult    44 Cadmium 50 mM 6 hrs, larvae L3    44 Cadmium 50 mM 12 hrs, larvae L3    56 Cadmium 50 mM 48 hrs, 4-day adult    57 Cadmium 100 mM 48 hrs, 4-day adult    45 Copper 0.5 mM 12 hrs, larvae L3    21 Copper 15 mM 48 hrs, 4-day adult    27 Zinc 5 mM 12 hrs, larvae L3    25 Zinc 4.5 mM 48 hrs, 4-day adult    30 Ethanol 2.5% 3 hrs, larvae L3    58 Ethanol 5% 3 hrs, larvae L3    52 Ethanol 10% 3 hrs, larvae L3    61 Caffeine 1.5 mg/ml 4 hrs, larvae L3    66 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    48 Caffeine 25 mg/ml 48 hrs, 4-day adult    20 Paraquat 5 mM 48 hrs, 4-day adult    43 Paraquat 10 mM 48 hrs, 4-day adult    67 Rotenone 2 μg 12 hrs, larvae L3    59 Rotenone 8 μg 12 hrs, larvae L3    58 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    19 cold shock, 4-day adult    12 heat shock, 4-day adult  (44) Cadmium 50 mM 6 hrs, larvae L3  (44) Cadmium 50 mM 12 hrs, larvae L3  (56) Cadmium 50 mM 48 hrs, 4-day adult  (57) Cadmium 100 mM 48 hrs, 4-day adult  (45) Copper 0.5 mM 12 hrs, larvae L3    21 Copper 15 mM 48 hrs, 4-day adult  27 Zinc 5 mM 12 hrs, larvae L3    25 Zinc 4.5 mM 48 hrs, 4-day adult  30 Ethanol 2.5% 3 hrs, larvae L3  (58) Ethanol 5% 3 hrs, larvae L3  (52) Ethanol 10% 3 hrs, larvae L3  (61) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (66) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (48) Caffeine 25 mg/ml 48 hrs, 4-day adult    20 Paraquat 5 mM 48 hrs, 4-day adult  (43) Paraquat 10 mM 48 hrs, 4-day adult  (67) Rotenone 2 μg 12 hrs, larvae L3  (59) Rotenone 8 μg 12 hrs, larvae L3  (58) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    19 cold shock, 4-day adult    12 heat shock, 4-day adult    44 Cadmium 50 mM 6 hrs, larvae L3    44 Cadmium 50 mM 12 hrs, larvae L3    56 Cadmium 50 mM 48 hrs, 4-day adult    57 Cadmium 100 mM 48 hrs, 4-day adult    45 Copper 0.5 mM 12 hrs, larvae L3    21 Copper 15 mM 48 hrs, 4-day adult    27 Zinc 5 mM 12 hrs, larvae L3    25 Zinc 4.5 mM 48 hrs, 4-day adult    30 Ethanol 2.5% 3 hrs, larvae L3    58 Ethanol 5% 3 hrs, larvae L3    52 Ethanol 10% 3 hrs, larvae L3    61 Caffeine 1.5 mg/ml 4 hrs, larvae L3    66 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    48 Caffeine 25 mg/ml 48 hrs, 4-day adult    20 Paraquat 5 mM 48 hrs, 4-day adult    43 Paraquat 10 mM 48 hrs, 4-day adult    67 Rotenone 2 μg 12 hrs, larvae L3    59 Rotenone 8 μg 12 hrs, larvae L3    58 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    19 cold shock, 4-day adult    12 heat shock, 4-day adult    44 Cadmium 50 mM 6 hrs, larvae L3    44 Cadmium 50 mM 12 hrs, larvae L3    56 Cadmium 50 mM 48 hrs, 4-day adult    57 Cadmium 100 mM 48 hrs, 4-day adult    45 Copper 0.5 mM 12 hrs, larvae L3    21 Copper 15 mM 48 hrs, 4-day adult    27 Zinc 5 mM 12 hrs, larvae L3    25 Zinc 4.5 mM 48 hrs, 4-day adult    30 Ethanol 2.5% 3 hrs, larvae L3    58 Ethanol 5% 3 hrs, larvae L3    52 Ethanol 10% 3 hrs, larvae L3    61 Caffeine 1.5 mg/ml 4 hrs, larvae L3    66 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    48 Caffeine 25 mg/ml 48 hrs, 4-day adult    20 Paraquat 5 mM 48 hrs, 4-day adult    43 Paraquat 10 mM 48 hrs, 4-day adult    67 Rotenone 2 μg 12 hrs, larvae L3    59 Rotenone 8 μg 12 hrs, larvae L3    58 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_09 mE1_20_mRNA_expression_cluster_02
External Data & Images
Linkouts	BDGP expression data • LD24274 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0036816 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG3979-RB FlyExpress - Embryonic expression images (BDGP data) • Show all FlyExpress processed images for Indy Stages(s) 1-3 Stages(s) 4-6 Stages(s) 7-8 Stages(s) 11-12 Stages(s) 13-16
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal | embryonic stage | partially IndyP115 viable Indy25 IndyCC00377 IndyEY01458 IndyEY13297 viable, with Scer\GAL4pnr-MD237 IndyGD2712 viable | poor IndyP115 viable | reduced IndyP115 Sterility Allele female fertile IndyP115 fertile Indy206 Indy302 IndyEY01458 IndyEY13297 IndyP115 male fertile IndyP115 Other Phenotypes Allele long lived Indy206 Indy302 Indyunspecified long lived | dominant Indy92 Indy159 Indy206 Indy265 Indy302 Phenotype manifest in Allele
Classical Alleles ( 49 )
For All Classical Alleles Show
Allele of Indy Class Mutagen Stocks Known lesion Indy206 P-element activity 1 Yes Indy25 1 Yes Indy302 P-element activity 1 Yes Indy5-HA-1062 1 -- Indy5-HA-1085 1 -- Indy5-SZ-3940 1 -- Indyc00473 piggyBac transposase 1 -- Indyc02704 piggyBac transposase 1 -- Indyc02706 piggyBac transposase 1 -- Indyc04172 piggyBac transposase 1 -- Indyc04366 piggyBac transposase 1 -- Indyc06366 piggyBac transposase 1 -- IndyCB-5824-3 1 -- IndyCB-6438-3 1 -- IndyCB-6522-3 1 -- Indyd07357 P-element activity 1 -- Indyd10530 P-element activity 1 -- Indye04082 piggyBac transposase 1 -- IndyEY01442 P-element activity 1 -- IndyEY01458 P-element activity 1 -- IndyEY13297 P-element activity 1 -- Indyf01065 piggyBac transposase 1 -- IndyKG07717 1 -- IndyMI01402 1 -- IndyMI06608 1 -- IndyNP1302 1 -- IndyNP1590 1 -- IndyNP2176 1 -- IndyNP2503 1 -- IndyNP5416 1 -- IndyNP5445 1 -- IndyNP5484 1 -- IndyNP6604 1 -- IndyNP7015 1 -- IndyNP7473 1 -- Indy159 P-element activity 0 Yes Indy265 P-element activity 0 Yes Indy92 P-element activity 0 -- Indyc04696 piggyBac transposase 0 -- IndyCC00377 P-element activity 0 Yes IndyCPTI003049 piggyBac transposase 0 Yes Indyd04839 P-element activity 0 -- Indyd05551 P-element activity 0 -- Indyd07872 P-element activity 0 -- IndyEP3044 P-element activity 0 Yes IndyEP3366 P-element activity 0 -- IndyP115 P-element activity 0 Yes Indyunspecified 0 -- IndyYC0017 Delta2-3 0 Yes
Alleles Carried on Transgenic Constructs ( 2 )
For All Alleles Carried on Transgenic Constructs Show
Allele of Indy Class Mutagen Stocks Known lesion IndyGD2712 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes IndyNIG.3979R in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD2712} NA P{NIG.3979R} NA
Insertions
	Type of insertions Name Expression data insertion of mobile activating element P{EP}IndyEP3044 NA P{EP}IndyEP3366 NA P{EPgy2}IndyEY01442 NA P{EPgy2}IndyEY01458 NA P{EPgy2}IndyEY13297 NA P{XP}Indyd04839 NA P{XP}Indyd05551 NA P{XP}Indyd07357 NA P{XP}Indyd07872 NA P{XP}Indyd10530 NA miscellaneous insertions Mi{MIC}IndyMI01402 NA Mi{MIC}IndyMI06608 NA P{}Indy92 NA P{}Indy265 NA P{PTT-GC}IndyCC00377 NA P{PTT-GC}IndyYC0017 NA P{RS3}IndyCB-5824-3 NA P{RS3}IndyCB-6438-3 NA P{RS3}IndyCB-6522-3 NA P{RS5}Indy5-HA-1062 NA P{RS5}Indy5-HA-1085 NA P{RS5}Indy5-SZ-3940 NA P{SUPor-P}IndyKG07717 NA P{UASp-YFP.CG9807}Indy25 NA PBac{754.P.FSVS-0}IndyCPTI003049 NA PBac{PB}Indyc00473 NA PBac{PB}Indyc02704 NA PBac{PB}Indyc02706 NA PBac{PB}Indyc04172 NA PBac{PB}Indyc04366 NA PBac{PB}Indyc04696 NA PBac{PB}Indyc06366 NA PBac{RB}Indye04082 NA PBac{WH}Indyf01065 NA insertion of enhancer trap binary system P{GawB}IndyNP1302 No P{GawB}IndyNP1590 No P{GawB}IndyNP2176 No P{GawB}IndyNP2503 No P{GawB}IndyNP5416 No P{GawB}IndyNP5445 No P{GawB}IndyNP5484 No P{GawB}IndyNP6604 No P{GawB}IndyNP7015 No P{GawB}IndyNP7473 No insertion of enhancer trap P{lacW}Indy159 No P{lacW}Indy206 No P{lacW}Indy302 No P{lArB}IndyP115 No
Gene Ontology: Function, Process & Cellular Component ( 8 unique terms )
Terms Based on Experimental Evidence ( 5 terms )
Molecular Function
CV term Evidence References
citrate transmembrane transporter activity inferred from direct assay (Inoue et al., 2002, Knauf et al., 2002) succinate transmembrane transporter activity inferred from direct assay (Inoue et al., 2002, Knauf et al., 2002)
Biological Process
CV term Evidence References
determination of adult lifespan inferred from direct assay (Wang et al., 2009) inferred from mutant phenotype (Rogina et al., 2000) NOT determination of adult lifespan inferred from mutant phenotype (Toivonen et al., 2007) regulation of sequestering of triglyceride inferred from direct assay (Wang et al., 2009)
Cellular Component
CV term Evidence References
plasma membrane inferred from direct assay (Knauf et al., 2002, Khanna et al., 2010)
Terms Based on Predictions or Assertions ( 4 terms )
Molecular Function
CV term Evidence References
tricarboxylic acid transmembrane transporter activity non-traceable author statement (Inoue, 2002.5.3)
Biological Process
CV term Evidence References
determination of adult lifespan traceable author statement (Boulianne, 2001, Aigaki et al., 2002, Helfand and Rogina, 2003, Helfand and Rogina, 2003) sodium ion transport inferred from electronic annotation with InterPro:IPR001898 (FlyBase Curators et al., 2004-) transmembrane transport inferred from electronic annotation with InterPro:IPR001898 (FlyBase Curators et al., 2004-)
Cellular Component ( 0 terms)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions Indy allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 65330 DroID - A comprehensive database of gene and protein interactions. • FBgn0036816 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 40049
Orthologs
OrthoDB Orthologs (103) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6HMJVW Dipteran inclusive ortholog search EOG6SJ5P2 Insect inclusive ortholog search EOG6TQK56 Arthropod inclusive ortholog search EOG6FXPPV Metazoa inclusive ortholog search EOG6SNDFX
Orthologs in Drosophila Species (EOG6HMJVW)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\Indy     Drosophila simulans   Dsim\GD12325     Drosophila sechellia   Dsec\GM14919 Y   Drosophila erecta   Dere\GG15722 Y   Drosophila yakuba   Dyak\GE22053 Y   Drosophila ananassae   Dana\GF10804 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA23740 Y   Drosophila persimilis   Dper\GL25253 Y   Drosophila willistoni   Dwil\GK20442     Drosophila virilis   Dvir\GJ13740 Y   Drosophila mojavensis   Dmoj\GI13959 Y   Drosophila grimshawi   Dgri\GH17192 Y
Orthologs in non-Drosophila Dipterans (EOG6SJ5P2)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL009863   Aedes aegypti Yellow fever mosquito  Aaeg\AAEL009856   Aedes aegypti Yellow fever mosquito  Aaeg\AAEL009860   Aedes aegypti Yellow fever mosquito  Aaeg\AAEL009855   Anopheles gambiae Malaria mosquito  Agam\AGAP007055   Anopheles gambiae Malaria mosquito  Agam\AGAP007054   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ004955   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ004954
Orthologs in non-Dipteran Insects (EOG6TQK56)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\GB40386 Y Apis mellifera Western honey bee  Amel\GB40381 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG007271 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG013454 Y Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH22545 Y Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH12848 Y Atta cephalotes Leafcutter ant  Acep\ACEP22003 Y Camponotus floridanus Florida carpenter ant  Cflo\CFLO22429 Y Camponotus floridanus Florida carpenter ant  Cflo\CFLO21348 Y Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL17684 Y Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL17681 Y Linepithema humile Argentine ant  Lhum\LH11966 Y Linepithema humile Argentine ant  Lhum\LH19337 Y Linepithema humile Argentine ant  Lhum\LH11965 Y Pogonomyrmex barbatus Red harvester ant  Pbar\PB20738 Y Pogonomyrmex barbatus Red harvester ant  Pbar\PB16316 Y Solenopsis invicta Red fire ant  Sinv\SINV13065 Y Solenopsis invicta Red fire ant  Sinv\SINV13041 Y Acyrthosiphon pisum Pea aphid  Apim\ACYPI087571 Y Bombyx mori Silkmoth  Bmor\BGIBMGA007274 Y Bombyx mori Silkmoth  Bmor\BGIBMGA007283 Y Bombyx mori Silkmoth  Bmor\BGIBMGA012800 Y Pediculus humanus Human body louse  Phum\PHUM047000 Y Tribolium castaneum Red flour beetle  Tcas\GLEAN_15326 Y Tribolium castaneum Red flour beetle  Tcas\GLEAN_15325 Y
Orthologs in non-Insect Arthropods (EOG6FXPPV)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\JGI_V11_307380 Y Daphnia pulex Water flea  Dpux\JGI_V11_308448 Y Daphnia pulex Water flea  Dpux\JGI_V11_327340 Y Daphnia pulex Water flea  Dpux\JGI_V11_198799 Y Daphnia pulex Water flea  Dpux\JGI_V11_63218 Y Daphnia pulex Water flea  Dpux\COI Y Ixodes scapularis Deer tick  Isca\ISCW023783 Y Ixodes scapularis Deer tick  Isca\ISCW000455 Y Ixodes scapularis Deer tick  Isca\ISCW000567 Y Ixodes scapularis Deer tick  Isca\ISCW013889 Y Ixodes scapularis Deer tick  Isca\ISCW009871 Y Ixodes scapularis Deer tick  Isca\ISCW003456 Y Ixodes scapularis Deer tick  Isca\ISCW007956 Y Ixodes scapularis Deer tick  Isca\ISCW004897 Y Ixodes scapularis Deer tick  Isca\ISCW004257 Y Ixodes scapularis Deer tick  Isca\ISCW007334 Y
Orthologs in non-Arthropod Metazoa (EOG6SNDFX)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Caenorhabditis elegans Nematode  Cele\B0285.6 Y Caenorhabditis elegans Nematode  Cele\nac-3 Y Caenorhabditis elegans Nematode  Cele\nac-1 Y Caenorhabditis elegans Nematode  Cele\nac-2 Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_017051gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_023846gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_023810gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_016679gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_015678gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_023812gn Y Danio rerio Zebrafish  Drer\OTTDARG00000028312 Y Danio rerio Zebrafish  Drer\slc13a2 Y Danio rerio Zebrafish  Drer\CR853282.1 Y Danio rerio Zebrafish  Drer\zgc:162495 Y Danio rerio Zebrafish  Drer\slc13a3 Y Danio rerio Zebrafish  Drer\slc13a1 Y Xenopus tropicalis Western clawed frog  Xtro\slc13a1 Y Xenopus tropicalis Western clawed frog  Xtro\slc13a4 Y Xenopus tropicalis Western clawed frog  Xtro\slc13a2 Y Xenopus tropicalis Western clawed frog  Xtro\slc13a3 Y Xenopus tropicalis Western clawed frog  Xtro\slc13a4 Y Xenopus tropicalis Western clawed frog  Xtro\slc13a5 Y Gallus gallus Domestic chicken  Ggal\SLC13A3 Y Gallus gallus Domestic chicken  Ggal\SLC13A4 Y Gallus gallus Domestic chicken  Ggal\SLC13A1 Y Gallus gallus Domestic chicken  Ggal\SLC13A5 Y Gallus gallus Domestic chicken  Ggal\SLC13A2 Y Mus musculus House mouse  Mmus\Slc13a1 Y Mus musculus House mouse  Mmus\Slc13a5 Y Mus musculus House mouse  Mmus\Slc13a4 Y Mus musculus House mouse  Mmus\Slc13a3 Y Mus musculus House mouse  Mmus\Slc13a2 Y Rattus norvegicus Norway rat  Rnor\Slc13a4 Y Rattus norvegicus Norway rat  Rnor\Slc13a2 Y Rattus norvegicus Norway rat  Rnor\Slc13a5 Y Rattus norvegicus Norway rat  Rnor\Slc13a3 Y Rattus norvegicus Norway rat  Rnor\Slc13a1 Y Homo sapiens Human  Hsap\SLC13A4 Y Homo sapiens Human  Hsap\SLC13A3 Y Homo sapiens Human  Hsap\SLC13A2 Y Homo sapiens Human  Hsap\SLC13A5 Y Homo sapiens Human  Hsap\SLC13A1 Y
Human Orthologs (5)
Gene OMIM HGNC Hsap\SLC13A4     Hsap\SLC13A3     Hsap\SLC13A2     Hsap\SLC13A5     Hsap\SLC13A1
AAA Orthologs (9) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila sechellia Dsec\GM14919 Drosophila erecta Dere\GG15722 Drosophila yakuba Dyak\GE22053 Drosophila ananassae Dana\GF10804 Drosophila pseudoobscura pseudoobscura Dpse\GA23740 Drosophila persimilis Dper\GL25253 Drosophila virilis Dvir\GJ13740 Drosophila mojavensis Dmoj\GI13959 Drosophila grimshawi Dgri\GH17192
Stocks & Reagents
Stocks Listed in FlyBase ( 37 )
Harvard	- P{XP}Indyd07357 - P{XP}Indyd10530 - PBac{PB}Indyc00473 - PBac{PB}Indyc02704 - PBac{PB}Indyc02706 - PBac{PB}Indyc04172 - PBac{PB}Indyc04366 - PBac{PB}Indyc06366 - PBac{RB}Indye04082 - PBac{WH}Indyf01065
VDRC	v9981 w1118; P{GD2712}v9981 v9982 w1118; P{GD2712}v9982/TM3
	More stocks available...
Genomic Clones ( 1 )
	BACR48N04 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 253 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	LD24274 RH67364
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT24505 AT28844 AT28911 GH27688 HL01773 LD16220 LD27949 LP01220 LP02226 LP04802 LP18732 LP24432 RE09572 RE09681 RE10441 RE11239 RE13584 RE15304 RE21272 RE21425 RE23710 RE23774 RE28427 RE29043 RE29828 RE33549 RE35536 RE39253 RE41535 RE43625 RE44418 RE44494 RE44558 RE45262 RE46135 RE49962 RE50376 RE53266 RE53355 RE55737 RE56228 RE56243 RE56938 RE63463 RE63527 RE67369 RE68458 RE70308 RE72079
Other clones	10585 10614 10650 16638 17178 21020 52781 58411 58454 80941 97418 99751 105788 149345 179743 193201 193734 214479.45 AA433278 bs19d08 CK01.25A.E5 CK01.59A.H12 CK01.79C.H1 CK01.84A.A10 CK01.90D.F2 CK01.102C.E5 CK01.119C.C4 Dmel_dig_007113_0605_1757 Dmel_dig_013469_0699_0790 Dmel_dig_015911_0595_0794 Dmel_neb_013226_0706_0465 Dmel_neb_013787_0128_1793 Dmel_neb_014455_0317_1978 EC051122 EK020205 EK047948 EK061729 EK066835 EK068112 EK091142 EK097908 EK110320 EK110360 EK113655 EK128538 EK134244 EK168863 EK170439 EK181064 EK222451 EK230711 EK254455 EK261057 EK284264 EK291207 EK296244 EP03462 EP03556 EP13204 EP14134 EP21831 ESG0110a.E21_A10 LD27191 RP003011859 RP003038653 RP003040254 RP003041797 RP003050272 RP003051506 RP003052002 RP003059882 RP003061234 RP003065927 RP003067898 RP003076795 RP003078152 RP003078193 RP003078871 RP003091948 RP003092044 RP003093634 RP003098247 RP003101942 RP003103208 RP003104557 RP003114125 RP003120259 RP003122186 RP003124954 RP003127151 RP003135456 RP003138366 RP003141879 RP003149019 RP003155565 RP003159246 RP003162857 RP003165553 RP003168270 RP003175868 RP003179048 RP003191288 RP003193927 RP003199697 RP003201151 RP003210559 RP003219094 RP003225524 RP003227959 RP003229642 RP003236461 RP003236897 RP003243566 RP003247886 RP003250562 RP003251474 RP003255342 RP003255570 RP003261435 RP003264682 RP003269141 RP003272098 RP003275824 RP003280227 RP003282014 RP003283163 RP003283311 RP003284784 RP003285537 RP003291280 RP003294753 RP003303466 RP003310799 RP003312510 RP003316795 RP003322922 RP003324232 RP003326183 RP003328322 RP003329145 RP003334316 RP003335611 RP003337742 RP003348624 RP003350853 RP003354527 RP003378393 RP003379031 RP003379336 RP003399214 RP003415202 RP003424501 RP003424887 RP003425884 RP003438165 RP003439317 RP003461525 RP003467965 RP003471741 RP003473341 RP003478347 RP003479541 RP003484076 RP003491201 RP003492546 RP003506501 RP003507884 RP003516579 RP003521520 RP003527106 RP003528230 RP003529445 RP003531662 RP003534926 RP003535290 RP003537147 RP003545662 RP003555786 RP003558789 RP003565163 RP003569810 RP003570449 RP003572723 RP003577415 RP003599669 RP003601879 RP003607382 RP003609569 RP003610385 RP003614097 RP003619117 RP003619254 RP003624232 RP003634422 RP003635208 RP003639378 RP003649430 RP003652508 RP003657795 RP003665510 RP003666804 RP003673846
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0036816 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 40049
Antibody Information
Other Information
Discoverer
Etymology
	The gene is named "I'm not dead yet" based on a quip in the movie "Monty Python and the Holy Grail". (Pennisi, 2000)
Identification
Relationship to Other Genes
Source for database identity of	Source for identity of: Indy CG3979 (Rogina et al., 2000)
Source for database merge of	Source for merge of: CG3979 anon-EST:fe3A7 (FlyBase, 1996-) Source for merge of: Indy anon-WO0172774.70 (FlyBase, 1996-) Source for merge of: Indy BEST:LP01220 (Rana, 2004.7.8)
Additional comments	Source for merge of Indy anon-WO0172774.70 was sequence comparison (date:051113). (FlyBase, 1996-) Source for merge of CG3979 anon-EST:fe3A7 was sequence comparison (date:000605). (FlyBase, 1996-)
Other Comments
	Indy encodes a transporter that mediates transport of succinate and also citrate across the plasma membrane. The transport of succinate is not cation dependent. The transport of citrate is Na+-independent, but is markedly stimulated at pH6.0 compared to pH7.5. (Knauf et al., 2002) Area matching Drosophila EST AA441327. This EST has sequence similarity to Rat sodium dependant dicarboxylate transporter, AB001321. (Davies, 2001.3.15) Heterozygous Indy mutants show a near doubling of the average adult life-span without a decline in fertility or physical activity. (Rogina et al., 2000)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_079426 NM_168778 NM_168779 NM_001169994 RefSeq (Proteins) • NP_524150 NP_730363 NP_730364 NP_001163465 DDBJ / EMBL / GenBank • AA433278 AA441327 AA567789 AA820509 AAF49226 AAF49227 AAF73384 AAM27515 AAN11670 AAN86815 ACZ94736 AF217399 AF509505 AI258115 AI455443 AQ025236 AQ073949 AX094175 AX260108 AX662047 AY102686 BZ665552 CAD79974 CL705880 CW848236 CZ466485 CZ468151 CZ468153 CZ469042 CZ469208 CZ469440 CZ470635 CZ474165 CZ474166 CZ474602 CZ475682 CZ475972 CZ477308 CZ481837 CZ483551 Entrez Gene - A searchable database of RefSeq genes. • 40049 UniProtKB/Swiss-Prot • Q9VVT2 UniProtKB/TrEMBL • E1JI19
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Sodium/sulphate symporter (IPR001898) BDGP expression data - Patterns of gene expression in Drosophila embryogenesis • LD24274
Linkouts
	BioGRID - A database of protein and genetic interactions • 65330 DroID - A comprehensive database of gene and protein interactions. • FBgn0036816 DRSC - Results from RNAi screens. • FBgn0036816 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0036816 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG3979-RB FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0036816 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 40049 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 40049 modMine - Data generated by the modENCODE project. • FBgn0036816
Synonyms & Secondary IDs ( 11 )
Reported As
Symbol Synonym	anon-EST:fe3A7   anon-WO0172774.70   BEST:LP01220   CG3979 (Hollien and Weissman, 2006, Quinones-Coello, 2007, Fujikawa et al., 2009, Khanna et al., 2010, Cammarato et al., 2011) drIndy (Inoue et al., 2002) indy (Kenyon, 2005, Boulianne, 2001) Indy (Quinones-Coello et al., 2007, Hollien and Weissman, 2006, Hollien and Weissman, 2006, Buszczak et al., 2007, Quinones-Coello, 2007, Zhang et al., 2007, Toivonen et al., 2007, Bauer et al., 2010, Neretti et al., 2009, Leandro et al., 2007, Chittaranjan et al., 2009, Lai et al., 2007, Toivonen et al., 2009, Wang et al., 2009, Fujikawa et al., 2009, Cook et al., 2010.2.12, Zhan et al., 2007, Bulgakova et al., 2004, Bulgakova et al., 2002, Japanese National Institute of Genetics, 2012.5.21) INDY (Carlson and Derr, 2007)
Name Synonym	anon-fast-evolving-3A7   I'm not dead yet (Rogina et al., 2000, Quinones-Coello et al., 2007, Carlson and Derr, 2007, Lai et al., 2007, Khanna et al., 2010, Zhan et al., 2007, Cammarato et al., 2011) I am not dead yet (Aigaki et al., 2002)
Secondary FlyBase IDs
	FBgn0025199 FBgn0045781 FBgn0046362
References ( 73 )
Generate a list of	All references relating to this gene ( 73 )
List References by type	Research paper  ( 23 ) Supplementary material  ( 10 ) Review  ( 9 ) Personal communication to FlyBase  ( 13 ) Abstract  ( 4 ) FlyBase analysis  ( 3 ) Note  ( 1 ) Stock list  ( 1 ) Patent  ( 3 ) DNA/RNA sequence record  ( 3 ) Website  ( 1 ) Curated genome annotation  ( 1 ) Interview  ( 1 )
Recent research papers ( 1 )
	Baycin-Hizal et al., 2011, J. Proteome Res. 10(6): 2777--2784 GlycoFly: A Database of Drosophila N-linked Glycoproteins Identified Using SPEG-MS Techniques. [FBrf0213834] Show all research papers ...
Recent reviews (0)
	All reviews listed in FlyBase were published before 2011 Show reviews ...