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Gene Dmel\CG6852

General Information
Symbol	Dmel\CG6852	Species	D. melanogaster
Name		Annotation symbol	CG6852
Feature type	protein_coding_gene	FlyBase ID	FBgn0036820
Gene Model Status	Current	Stock availability	4 publicly available
Genomic Location
Chromosome (arm)	3L	Recombination map
Cytogenetic map	75E2-75E2	Sequence location	3L:18,862,330..18,863,157 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG6852 (FBgn0036820). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function: protein disulfide oxidoreductase activity; electron carrier activity. There is experimental evidence that it is involved in the biological process: neurogenesis. 4 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Glutaredoxin; Glutaredoxin active site; Glutaredoxin subgroup; Glutaredoxin, eukaryotic/virial; Thioredoxin-like fold. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderately high expression. Peak expression observed within 18-24 hour embryonic stages, at stages throughout the larval period, in stages of adults of both sexes. Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult organs/tissues expressed at high levels. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, adult thoracico-abdominal ganglion, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult spermathecae, adult male accessory gland, larval/adult carcass. Expression at moderate levels in the following post-embryonic organs or tissues: larval/adult central nervous system, adult ovary. Comments on Affy2 ProbeSet: ProbeSet 1635075_at completely aligns to an exonic region common to each of the 2 FlyBase-annotated transcript isoforms of CG6852. Gene sequence location is 3L:18862330..18863157.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 75E2-75E2   Limits computationally determined from genome sequence between P{lacW}l(3)j14E7j14E7 and P{lacW}l(3)j4E6j4E6
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG6852 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.40 Gene model reviewed during 5.46
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG6852-RA FBtr0075063  NM_140808   595   114 CG6852-RC FBtr0308813  NM_001259898   607   114
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG6852-PA   FBpp0074830   12.4   114   8.71     NP_649065   AAF49222 CG6852-PC   FBpp0300970   12.4   114   8.71     NP_001246827   AFH04498
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Glutaredoxin (IPR002109) Glutaredoxin, eukaryotic/virial (IPR011899) Thioredoxin-like fold (IPR012336) Glutaredoxin subgroup (IPR014025) Glutaredoxin active site (IPR011767)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE014296 AAF49222   AE014296 AFH04498   AI404887   AY118819 AAM50679   EL871344   EL871461   EV585370
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9VVT6 B7Z076
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult organs/tissues expressed at high levels. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, adult thoracico-abdominal ganglion, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult spermathecae, adult male accessory gland, larval/adult carcass. Expression at moderate levels in the following post-embryonic organs or tissues: larval/adult central nervous system, adult ovary. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    408.925 Larval Midgut    1404.2 Larval Hindgut    824 Larval Malpighian Tubules    2095.7 Larval Fat Body    1467.4 Larval Salivary Gland    1711.8 Larval Trachea    641.5 Larval Carcass    615.45 Adult Head    703.8 Adult Eye    1052.475 Adult Brain    488.3 Adult Thoracic-Abdominal Ganglion    591.7 Adult Crop    618.8 Adult Midgut    1139 Adult Hindgut    743.4 Adult Malpighian Tubules    1844.4 Adult Fat Body    2011.5 Adult Salivary Gland    1581.8 Adult Heart    1264.65 Adult VirginFemale Spermatheca    2649.1 Adult InseminatedFemale Spermatheca    2332 Adult Ovary    379.3 Adult Testis    91.5 Adult Male Accessory Gland    1112.2 Adult Carcass    981.4 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    408.925 Larval Midgut  (1404.2) Larval Hindgut  (824) Larval Malpighian Tubules  (2095.7) Larval Fat Body  (1467.4) Larval Salivary Gland  (1711.8) Larval Trachea  (641.5) Larval Carcass  (615.45) Adult Head  (703.8) Adult Eye  (1052.475) Adult Brain    488.3 Adult Thoracic-Abdominal Ganglion  (591.7) Adult Crop  (618.8) Adult Midgut  (1139) Adult Hindgut  (743.4) Adult Malpighian Tubules  (1844.4) Adult Fat Body  (2011.5) Adult Salivary Gland  (1581.8) Adult Heart  (1264.65) Adult VirginFemale Spermatheca  (2649.1) Adult InseminatedFemale Spermatheca  (2332) Adult Ovary    379.3 Adult Testis    91.5 Adult Male Accessory Gland  (1112.2) Adult Carcass  (981.4) Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    408.925 Larval Midgut  (1404.2) Larval Hindgut    824 Larval Malpighian Tubules  (2095.7) Larval Fat Body  (1467.4) Larval Salivary Gland  (1711.8) Larval Trachea    641.5 Larval Carcass    615.45 Adult Head    703.8 Adult Eye  1052.475 Adult Brain    488.3 Adult Thoracic-Abdominal Ganglion    591.7 Adult Crop    618.8 Adult Midgut  (1139) Adult Hindgut    743.4 Adult Malpighian Tubules  (1844.4) Adult Fat Body  (2011.5) Adult Salivary Gland  (1581.8) Adult Heart  (1264.65) Adult VirginFemale Spermatheca  (2649.1) Adult InseminatedFemale Spermatheca  (2332) Adult Ovary    379.3 Adult Testis    91.5 Adult Male Accessory Gland  (1112.2) Adult Carcass    981.4 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    408.925 Larval Midgut    1404.2 Larval Hindgut    824 Larval Malpighian Tubules    2095.7 Larval Fat Body    1467.4 Larval Salivary Gland    1711.8 Larval Trachea    641.5 Larval Carcass    615.45 Adult Head    703.8 Adult Eye    1052.475 Adult Brain    488.3 Adult Thoracic-Abdominal Ganglion    591.7 Adult Crop    618.8 Adult Midgut    1139 Adult Hindgut    743.4 Adult Malpighian Tubules    1844.4 Adult Fat Body    2011.5 Adult Salivary Gland    1581.8 Adult Heart    1264.65 Adult VirginFemale Spermatheca    2649.1 Adult InseminatedFemale Spermatheca    2332 Adult Ovary    379.3 Adult Testis    91.5 Adult Male Accessory Gland    1112.2 Adult Carcass    981.4 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    408.925 Larval Midgut    1404.2 Larval Hindgut    824 Larval Malpighian Tubules    2095.7 Larval Fat Body    1467.4 Larval Salivary Gland    1711.8 Larval Trachea    641.5 Larval Carcass    615.45 Adult Head    703.8 Adult Eye    1052.475 Adult Brain    488.3 Adult Thoracic-Abdominal Ganglion    591.7 Adult Crop    618.8 Adult Midgut    1139 Adult Hindgut    743.4 Adult Malpighian Tubules    1844.4 Adult Fat Body    2011.5 Adult Salivary Gland    1581.8 Adult Heart    1264.65 Adult VirginFemale Spermatheca    2649.1 Adult InseminatedFemale Spermatheca    2332 Adult Ovary    379.3 Adult Testis    91.5 Adult Male Accessory Gland    1112.2 Adult Carcass    981.4 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    408.925 Larval Midgut  (1404.2) Larval Hindgut  (824) Larval Malpighian Tubules  (2095.7) Larval Fat Body  (1467.4) Larval Salivary Gland  (1711.8) Larval Trachea  641.5 Larval Carcass  615.45 Adult Head  703.8 Adult Eye  (1052.475) Adult Brain    488.3 Adult Thoracic-Abdominal Ganglion  591.7 Adult Crop  618.8 Adult Midgut  (1139) Adult Hindgut  743.4 Adult Malpighian Tubules  (1844.4) Adult Fat Body  (2011.5) Adult Salivary Gland  (1581.8) Adult Heart  (1264.65) Adult VirginFemale Spermatheca  (2649.1) Adult InseminatedFemale Spermatheca  (2332) Adult Ovary    379.3 Adult Testis    91.5 Adult Male Accessory Gland  (1112.2) Adult Carcass  (981.4) Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    408.925 Larval Midgut  1404.2 Larval Hindgut    824 Larval Malpighian Tubules  (2095.7) Larval Fat Body  1467.4 Larval Salivary Gland  1711.8 Larval Trachea    641.5 Larval Carcass    615.45 Adult Head    703.8 Adult Eye  1052.475 Adult Brain    488.3 Adult Thoracic-Abdominal Ganglion    591.7 Adult Crop    618.8 Adult Midgut  1139 Adult Hindgut    743.4 Adult Malpighian Tubules  (1844.4) Adult Fat Body  (2011.5) Adult Salivary Gland  1581.8 Adult Heart  1264.65 Adult VirginFemale Spermatheca  (2649.1) Adult InseminatedFemale Spermatheca  (2332) Adult Ovary    379.3 Adult Testis    91.5 Adult Male Accessory Gland  1112.2 Adult Carcass    981.4 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    408.925 Larval Midgut    1404.2 Larval Hindgut    824 Larval Malpighian Tubules    2095.7 Larval Fat Body    1467.4 Larval Salivary Gland    1711.8 Larval Trachea    641.5 Larval Carcass    615.45 Adult Head    703.8 Adult Eye    1052.475 Adult Brain    488.3 Adult Thoracic-Abdominal Ganglion    591.7 Adult Crop    618.8 Adult Midgut    1139 Adult Hindgut    743.4 Adult Malpighian Tubules    1844.4 Adult Fat Body    2011.5 Adult Salivary Gland    1581.8 Adult Heart    1264.65 Adult VirginFemale Spermatheca    2649.1 Adult InseminatedFemale Spermatheca    2332 Adult Ovary    379.3 Adult Testis    91.5 Adult Male Accessory Gland    1112.2 Adult Carcass    981.4 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    703.8   NA  Eye    1052.475   NA  Brain    488.3   408.925  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    591.7   NA  Crop    618.8   1404.2  Midgut    1139   824  Hindgut    743.4   2095.7  Malpighian Tubules    1844.4   1467.4  Fat Body    2011.5   1711.8  Salivary Gland    1581.8   NA  Heart    1264.65   641.5  Trachea    NA   NA  VirginFemale Spermatheca    2649.1   NA  InseminatedFemale Spermatheca    2332   NA  Ovary    379.3   NA  Testis    91.5   NA  Male Accessory Gland    1112.2   615.45  Carcass    981.4 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    40 central nervous system, larvae L3    36 central nervous system, pupae P8    42 head, virgin 1-day female    104 head, virgin 4-day female    76 head, virgin 20-day female    70 head, mated 1-day female    92 head, mated 4-day female    68 head, mated 20-day female    56 head, mated 1-day male    90 head, mated 4-day male    86 head, mated 20-day male    109 salivary gland, larvae L3 wandering    90 salivary gland, white prepupae    96 digestive system, larvae L3 wandering    122 digestive system, 1-day adult    188 digestive system, 4-day adult    118 digestive system, 20-day adult    76 fat body, larvae L3 wandering    43 fat body, white prepupae    46 fat body, pupae P8    64 carcass, larvae L3 wandering    49 carcass, 1-day adult    85 carcass, 4-day adult    78 carcass, 20-day adult    69 ovary, virgin 4-day female    65 ovary, mated 4-day female    59 testis, mated 4-day male    56 accessory gland, mated 4-day male    105 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (40) central nervous system, larvae L3  (36) central nervous system, pupae P8  (42) head, virgin 1-day female  (104) head, virgin 4-day female  (76) head, virgin 20-day female  (70) head, mated 1-day female  (92) head, mated 4-day female  (68) head, mated 20-day female  (56) head, mated 1-day male  (90) head, mated 4-day male  (86) head, mated 20-day male  (109) salivary gland, larvae L3 wandering  (90) salivary gland, white prepupae  (96) digestive system, larvae L3 wandering  (122) digestive system, 1-day adult  (188) digestive system, 4-day adult  (118) digestive system, 20-day adult  (76) fat body, larvae L3 wandering  (43) fat body, white prepupae  (46) fat body, pupae P8  (64) carcass, larvae L3 wandering  (49) carcass, 1-day adult  (85) carcass, 4-day adult  (78) carcass, 20-day adult  (69) ovary, virgin 4-day female  (65) ovary, mated 4-day female  (59) testis, mated 4-day male  (56) accessory gland, mated 4-day male  (105) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    40 central nervous system, larvae L3    36 central nervous system, pupae P8    42 head, virgin 1-day female  104 head, virgin 4-day female    76 head, virgin 20-day female    70 head, mated 1-day female    92 head, mated 4-day female    68 head, mated 20-day female    56 head, mated 1-day male    90 head, mated 4-day male    86 head, mated 20-day male  (109) salivary gland, larvae L3 wandering    90 salivary gland, white prepupae    96 digestive system, larvae L3 wandering  (122) digestive system, 1-day adult  (188) digestive system, 4-day adult  (118) digestive system, 20-day adult    76 fat body, larvae L3 wandering    43 fat body, white prepupae    46 fat body, pupae P8    64 carcass, larvae L3 wandering    49 carcass, 1-day adult    85 carcass, 4-day adult    78 carcass, 20-day adult    69 ovary, virgin 4-day female    65 ovary, mated 4-day female    59 testis, mated 4-day male    56 accessory gland, mated 4-day male  105 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    40 central nervous system, larvae L3    36 central nervous system, pupae P8    42 head, virgin 1-day female    104 head, virgin 4-day female    76 head, virgin 20-day female    70 head, mated 1-day female    92 head, mated 4-day female    68 head, mated 20-day female    56 head, mated 1-day male    90 head, mated 4-day male    86 head, mated 20-day male    109 salivary gland, larvae L3 wandering    90 salivary gland, white prepupae    96 digestive system, larvae L3 wandering    122 digestive system, 1-day adult    188 digestive system, 4-day adult    118 digestive system, 20-day adult    76 fat body, larvae L3 wandering    43 fat body, white prepupae    46 fat body, pupae P8    64 carcass, larvae L3 wandering    49 carcass, 1-day adult    85 carcass, 4-day adult    78 carcass, 20-day adult    69 ovary, virgin 4-day female    65 ovary, mated 4-day female    59 testis, mated 4-day male    56 accessory gland, mated 4-day male    105 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    40 central nervous system, larvae L3    36 central nervous system, pupae P8    42 head, virgin 1-day female    104 head, virgin 4-day female    76 head, virgin 20-day female    70 head, mated 1-day female    92 head, mated 4-day female    68 head, mated 20-day female    56 head, mated 1-day male    90 head, mated 4-day male    86 head, mated 20-day male    109 salivary gland, larvae L3 wandering    90 salivary gland, white prepupae    96 digestive system, larvae L3 wandering    122 digestive system, 1-day adult    188 digestive system, 4-day adult    118 digestive system, 20-day adult    76 fat body, larvae L3 wandering    43 fat body, white prepupae    46 fat body, pupae P8    64 carcass, larvae L3 wandering    49 carcass, 1-day adult    85 carcass, 4-day adult    78 carcass, 20-day adult    69 ovary, virgin 4-day female    65 ovary, mated 4-day female    59 testis, mated 4-day male    56 accessory gland, mated 4-day male    105 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (40) central nervous system, larvae L3  (36) central nervous system, pupae P8  (42) head, virgin 1-day female  (104) head, virgin 4-day female  (76) head, virgin 20-day female  (70) head, mated 1-day female  (92) head, mated 4-day female  (68) head, mated 20-day female  (56) head, mated 1-day male  (90) head, mated 4-day male  (86) head, mated 20-day male  (109) salivary gland, larvae L3 wandering  (90) salivary gland, white prepupae  (96) digestive system, larvae L3 wandering  (122) digestive system, 1-day adult  (188) digestive system, 4-day adult  (118) digestive system, 20-day adult  (76) fat body, larvae L3 wandering  (43) fat body, white prepupae  (46) fat body, pupae P8  (64) carcass, larvae L3 wandering  (49) carcass, 1-day adult  (85) carcass, 4-day adult  (78) carcass, 20-day adult  (69) ovary, virgin 4-day female  (65) ovary, mated 4-day female  (59) testis, mated 4-day male  (56) accessory gland, mated 4-day male  (105) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    40 central nervous system, larvae L3    36 central nervous system, pupae P8    42 head, virgin 1-day female  104 head, virgin 4-day female    76 head, virgin 20-day female    70 head, mated 1-day female    92 head, mated 4-day female    68 head, mated 20-day female    56 head, mated 1-day male    90 head, mated 4-day male    86 head, mated 20-day male  109 salivary gland, larvae L3 wandering    90 salivary gland, white prepupae    96 digestive system, larvae L3 wandering  122 digestive system, 1-day adult  (188) digestive system, 4-day adult  118 digestive system, 20-day adult    76 fat body, larvae L3 wandering    43 fat body, white prepupae    46 fat body, pupae P8    64 carcass, larvae L3 wandering    49 carcass, 1-day adult    85 carcass, 4-day adult    78 carcass, 20-day adult    69 ovary, virgin 4-day female    65 ovary, mated 4-day female    59 testis, mated 4-day male    56 accessory gland, mated 4-day male  105 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    40 central nervous system, larvae L3    36 central nervous system, pupae P8    42 head, virgin 1-day female    104 head, virgin 4-day female    76 head, virgin 20-day female    70 head, mated 1-day female    92 head, mated 4-day female    68 head, mated 20-day female    56 head, mated 1-day male    90 head, mated 4-day male    86 head, mated 20-day male    109 salivary gland, larvae L3 wandering    90 salivary gland, white prepupae    96 digestive system, larvae L3 wandering    122 digestive system, 1-day adult    188 digestive system, 4-day adult    118 digestive system, 20-day adult    76 fat body, larvae L3 wandering    43 fat body, white prepupae    46 fat body, pupae P8    64 carcass, larvae L3 wandering    49 carcass, 1-day adult    85 carcass, 4-day adult    78 carcass, 20-day adult    69 ovary, virgin 4-day female    65 ovary, mated 4-day female    59 testis, mated 4-day male    56 accessory gland, mated 4-day male    105 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderately high expression. Peak expression observed within 18-24 hour embryonic stages, at stages throughout the larval period, in stages of adults of both sexes. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    36 embryo 02-04hr    19 embryo 04-06hr    17 embryo 06-08hr    16 embryo 08-10hr    19 embryo 10-12hr    27 embryo 12-14hr    25 embryo 14-16hr    22 embryo 16-18hr    36 embryo 18-20hr    33 embryo 20-22hr    53 embryo 22-24hr    60 larva L1    65 larva L2    90 larva L3 12hr old    73 larva L3 puffstage 1-2    82 larva L3 puffstage 3-6    51 larva L3 puffstage 7-9    55 white prepupae new    38 white prepupae 12hr    37 white prepupae 24hr    27 pupae 2d postWPP    38 pupae 3d postWPP    40 pupae 4d postWPP    32 adult male 01day    66 adult male 05day    61 adult male 30day    43 adult female 01day    46 adult female 05day    57 adult female 30day    63 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (36) embryo 02-04hr    19 embryo 04-06hr    17 embryo 06-08hr    16 embryo 08-10hr    19 embryo 10-12hr  (27) embryo 12-14hr    25 embryo 14-16hr    22 embryo 16-18hr  (36) embryo 18-20hr  (33) embryo 20-22hr  (53) embryo 22-24hr  (60) larva L1  (65) larva L2  (90) larva L3 12hr old  (73) larva L3 puffstage 1-2  (82) larva L3 puffstage 3-6  (51) larva L3 puffstage 7-9  (55) white prepupae new  (38) white prepupae 12hr  (37) white prepupae 24hr  (27) pupae 2d postWPP  (38) pupae 3d postWPP  (40) pupae 4d postWPP  (32) adult male 01day  (66) adult male 05day  (61) adult male 30day  (43) adult female 01day  (46) adult female 05day  (57) adult female 30day  (63) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    36 embryo 02-04hr    19 embryo 04-06hr    17 embryo 06-08hr    16 embryo 08-10hr    19 embryo 10-12hr    27 embryo 12-14hr    25 embryo 14-16hr    22 embryo 16-18hr    36 embryo 18-20hr    33 embryo 20-22hr    53 embryo 22-24hr    60 larva L1    65 larva L2    90 larva L3 12hr old    73 larva L3 puffstage 1-2    82 larva L3 puffstage 3-6    51 larva L3 puffstage 7-9    55 white prepupae new    38 white prepupae 12hr    37 white prepupae 24hr    27 pupae 2d postWPP    38 pupae 3d postWPP    40 pupae 4d postWPP    32 adult male 01day    66 adult male 05day    61 adult male 30day    43 adult female 01day    46 adult female 05day    57 adult female 30day    63 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    36 embryo 02-04hr    19 embryo 04-06hr    17 embryo 06-08hr    16 embryo 08-10hr    19 embryo 10-12hr    27 embryo 12-14hr    25 embryo 14-16hr    22 embryo 16-18hr    36 embryo 18-20hr    33 embryo 20-22hr    53 embryo 22-24hr    60 larva L1    65 larva L2    90 larva L3 12hr old    73 larva L3 puffstage 1-2    82 larva L3 puffstage 3-6    51 larva L3 puffstage 7-9    55 white prepupae new    38 white prepupae 12hr    37 white prepupae 24hr    27 pupae 2d postWPP    38 pupae 3d postWPP    40 pupae 4d postWPP    32 adult male 01day    66 adult male 05day    61 adult male 30day    43 adult female 01day    46 adult female 05day    57 adult female 30day    63 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    36 embryo 02-04hr    19 embryo 04-06hr    17 embryo 06-08hr    16 embryo 08-10hr    19 embryo 10-12hr    27 embryo 12-14hr    25 embryo 14-16hr    22 embryo 16-18hr    36 embryo 18-20hr    33 embryo 20-22hr    53 embryo 22-24hr    60 larva L1    65 larva L2    90 larva L3 12hr old    73 larva L3 puffstage 1-2    82 larva L3 puffstage 3-6    51 larva L3 puffstage 7-9    55 white prepupae new    38 white prepupae 12hr    37 white prepupae 24hr    27 pupae 2d postWPP    38 pupae 3d postWPP    40 pupae 4d postWPP    32 adult male 01day    66 adult male 05day    61 adult male 30day    43 adult female 01day    46 adult female 05day    57 adult female 30day    63 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (36) embryo 02-04hr    19 embryo 04-06hr    17 embryo 06-08hr    16 embryo 08-10hr    19 embryo 10-12hr  27 embryo 12-14hr    25 embryo 14-16hr    22 embryo 16-18hr  (36) embryo 18-20hr  (33) embryo 20-22hr  (53) embryo 22-24hr  (60) larva L1  (65) larva L2  (90) larva L3 12hr old  (73) larva L3 puffstage 1-2  (82) larva L3 puffstage 3-6  (51) larva L3 puffstage 7-9  (55) white prepupae new  (38) white prepupae 12hr  (37) white prepupae 24hr  27 pupae 2d postWPP  (38) pupae 3d postWPP  (40) pupae 4d postWPP  32 adult male 01day  (66) adult male 05day  (61) adult male 30day  (43) adult female 01day  (46) adult female 05day  (57) adult female 30day  (63) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    36 embryo 02-04hr    19 embryo 04-06hr    17 embryo 06-08hr    16 embryo 08-10hr    19 embryo 10-12hr    27 embryo 12-14hr    25 embryo 14-16hr    22 embryo 16-18hr    36 embryo 18-20hr    33 embryo 20-22hr    53 embryo 22-24hr    60 larva L1    65 larva L2    90 larva L3 12hr old    73 larva L3 puffstage 1-2    82 larva L3 puffstage 3-6    51 larva L3 puffstage 7-9    55 white prepupae new    38 white prepupae 12hr    37 white prepupae 24hr    27 pupae 2d postWPP    38 pupae 3d postWPP    40 pupae 4d postWPP    32 adult male 01day    66 adult male 05day    61 adult male 30day    43 adult female 01day    46 adult female 05day    57 adult female 30day    63 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    36 embryo 02-04hr    19 embryo 04-06hr    17 embryo 06-08hr    16 embryo 08-10hr    19 embryo 10-12hr    27 embryo 12-14hr    25 embryo 14-16hr    22 embryo 16-18hr    36 embryo 18-20hr    33 embryo 20-22hr    53 embryo 22-24hr    60 larva L1    65 larva L2    90 larva L3 12hr old    73 larva L3 puffstage 1-2    82 larva L3 puffstage 3-6    51 larva L3 puffstage 7-9    55 white prepupae new    38 white prepupae 12hr    37 white prepupae 24hr    27 pupae 2d postWPP    38 pupae 3d postWPP    40 pupae 4d postWPP    32 adult male 01day    66 adult male 05day    61 adult male 30day    43 adult female 01day    46 adult female 05day    57 adult female 30day    63 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    21 Schneider line 2 Sg4    16 embryonic 1182-4H    16 embryonic GM2    45 embryonic Kc167    21 embryonic S1    37 embryonic S3    55 leg disc CME L1    11 wing disc CME-W2    47 wing disc ML-DmD8    11 wing disc ML-DmD9    49 wing disc ML-DmD16-c3    26 wing disc ML-DmD21    71 wing disc ML-DmD32    34 haltere disc ML-DmD17-c3    34 eye-antennal disc ML-DmD11    29 antennal disc ML-DmD20-c5    24 mixed discs ML-DmD4-c1    48 CNS ML-DmBG1-c1    44 CNS ML-DmBG2-c2    35 tumorous blood cells mbn2    21 ovary fGS/OSS    20 ovary OSC    16 ovary OSS    15 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    21 Schneider line 2 Sg4    16 embryonic 1182-4H    16 embryonic GM2  (45) embryonic Kc167    21 embryonic S1  (37) embryonic S3  (55) leg disc CME L1    11 wing disc CME-W2  (47) wing disc ML-DmD8    11 wing disc ML-DmD9  (49) wing disc ML-DmD16-c3  26 wing disc ML-DmD21  (71) wing disc ML-DmD32  (34) haltere disc ML-DmD17-c3  (34) eye-antennal disc ML-DmD11  (29) antennal disc ML-DmD20-c5    24 mixed discs ML-DmD4-c1  (48) CNS ML-DmBG1-c1  (44) CNS ML-DmBG2-c2  (35) tumorous blood cells mbn2    21 ovary fGS/OSS    20 ovary OSC    16 ovary OSS    15 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    21 Schneider line 2 Sg4    16 embryonic 1182-4H    16 embryonic GM2    45 embryonic Kc167    21 embryonic S1    37 embryonic S3    55 leg disc CME L1    11 wing disc CME-W2    47 wing disc ML-DmD8    11 wing disc ML-DmD9    49 wing disc ML-DmD16-c3    26 wing disc ML-DmD21    71 wing disc ML-DmD32    34 haltere disc ML-DmD17-c3    34 eye-antennal disc ML-DmD11    29 antennal disc ML-DmD20-c5    24 mixed discs ML-DmD4-c1    48 CNS ML-DmBG1-c1    44 CNS ML-DmBG2-c2    35 tumorous blood cells mbn2    21 ovary fGS/OSS    20 ovary OSC    16 ovary OSS    15 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    21 Schneider line 2 Sg4    16 embryonic 1182-4H    16 embryonic GM2    45 embryonic Kc167    21 embryonic S1    37 embryonic S3    55 leg disc CME L1    11 wing disc CME-W2    47 wing disc ML-DmD8    11 wing disc ML-DmD9    49 wing disc ML-DmD16-c3    26 wing disc ML-DmD21    71 wing disc ML-DmD32    34 haltere disc ML-DmD17-c3    34 eye-antennal disc ML-DmD11    29 antennal disc ML-DmD20-c5    24 mixed discs ML-DmD4-c1    48 CNS ML-DmBG1-c1    44 CNS ML-DmBG2-c2    35 tumorous blood cells mbn2    21 ovary fGS/OSS    20 ovary OSC    16 ovary OSS    15 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    21 Schneider line 2 Sg4    16 embryonic 1182-4H    16 embryonic GM2    45 embryonic Kc167    21 embryonic S1    37 embryonic S3    55 leg disc CME L1    11 wing disc CME-W2    47 wing disc ML-DmD8    11 wing disc ML-DmD9    49 wing disc ML-DmD16-c3    26 wing disc ML-DmD21    71 wing disc ML-DmD32    34 haltere disc ML-DmD17-c3    34 eye-antennal disc ML-DmD11    29 antennal disc ML-DmD20-c5    24 mixed discs ML-DmD4-c1    48 CNS ML-DmBG1-c1    44 CNS ML-DmBG2-c2    35 tumorous blood cells mbn2    21 ovary fGS/OSS    20 ovary OSC    16 ovary OSS    15 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    21 Schneider line 2 Sg4    16 embryonic 1182-4H    16 embryonic GM2  (45) embryonic Kc167    21 embryonic S1  (37) embryonic S3  (55) leg disc CME L1    11 wing disc CME-W2  (47) wing disc ML-DmD8    11 wing disc ML-DmD9  (49) wing disc ML-DmD16-c3  26 wing disc ML-DmD21  (71) wing disc ML-DmD32  (34) haltere disc ML-DmD17-c3  (34) eye-antennal disc ML-DmD11  29 antennal disc ML-DmD20-c5    24 mixed discs ML-DmD4-c1  (48) CNS ML-DmBG1-c1  (44) CNS ML-DmBG2-c2  (35) tumorous blood cells mbn2    21 ovary fGS/OSS    20 ovary OSC    16 ovary OSS    15 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    21 Schneider line 2 Sg4    16 embryonic 1182-4H    16 embryonic GM2    45 embryonic Kc167    21 embryonic S1    37 embryonic S3    55 leg disc CME L1    11 wing disc CME-W2    47 wing disc ML-DmD8    11 wing disc ML-DmD9    49 wing disc ML-DmD16-c3    26 wing disc ML-DmD21    71 wing disc ML-DmD32    34 haltere disc ML-DmD17-c3    34 eye-antennal disc ML-DmD11    29 antennal disc ML-DmD20-c5    24 mixed discs ML-DmD4-c1    48 CNS ML-DmBG1-c1    44 CNS ML-DmBG2-c2    35 tumorous blood cells mbn2    21 ovary fGS/OSS    20 ovary OSC    16 ovary OSS    15 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    21 Schneider line 2 Sg4    16 embryonic 1182-4H    16 embryonic GM2    45 embryonic Kc167    21 embryonic S1    37 embryonic S3    55 leg disc CME L1    11 wing disc CME-W2    47 wing disc ML-DmD8    11 wing disc ML-DmD9    49 wing disc ML-DmD16-c3    26 wing disc ML-DmD21    71 wing disc ML-DmD32    34 haltere disc ML-DmD17-c3    34 eye-antennal disc ML-DmD11    29 antennal disc ML-DmD20-c5    24 mixed discs ML-DmD4-c1    48 CNS ML-DmBG1-c1    44 CNS ML-DmBG2-c2    35 tumorous blood cells mbn2    21 ovary fGS/OSS    20 ovary OSC    16 ovary OSS    15 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    33 cold shock, 4-day adult    28 heat shock, 4-day adult    72 Cadmium 50 mM 6 hrs, larvae L3    104 Cadmium 50 mM 12 hrs, larvae L3    118 Cadmium 50 mM 48 hrs, 4-day adult    84 Cadmium 100 mM 48 hrs, 4-day adult    60 Copper 0.5 mM 12 hrs, larvae L3    46 Copper 15 mM 48 hrs, 4-day adult    49 Zinc 5 mM 12 hrs, larvae L3    47 Zinc 4.5 mM 48 hrs, 4-day adult    78 Ethanol 2.5% 3 hrs, larvae L3    48 Ethanol 5% 3 hrs, larvae L3    162 Ethanol 10% 3 hrs, larvae L3    94 Caffeine 1.5 mg/ml 4 hrs, larvae L3    125 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    79 Caffeine 25 mg/ml 48 hrs, 4-day adult    24 Paraquat 5 mM 48 hrs, 4-day adult    69 Paraquat 10 mM 48 hrs, 4-day adult    56 Rotenone 2 μg 12 hrs, larvae L3    133 Rotenone 8 μg 12 hrs, larvae L3    71 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult  (33) cold shock, 4-day adult  (28) heat shock, 4-day adult  (72) Cadmium 50 mM 6 hrs, larvae L3  (104) Cadmium 50 mM 12 hrs, larvae L3  (118) Cadmium 50 mM 48 hrs, 4-day adult  (84) Cadmium 100 mM 48 hrs, 4-day adult  (60) Copper 0.5 mM 12 hrs, larvae L3  (46) Copper 15 mM 48 hrs, 4-day adult  (49) Zinc 5 mM 12 hrs, larvae L3  (47) Zinc 4.5 mM 48 hrs, 4-day adult  (78) Ethanol 2.5% 3 hrs, larvae L3  (48) Ethanol 5% 3 hrs, larvae L3  (162) Ethanol 10% 3 hrs, larvae L3  (94) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (125) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (79) Caffeine 25 mg/ml 48 hrs, 4-day adult    24 Paraquat 5 mM 48 hrs, 4-day adult  (69) Paraquat 10 mM 48 hrs, 4-day adult  (56) Rotenone 2 μg 12 hrs, larvae L3  (133) Rotenone 8 μg 12 hrs, larvae L3  (71) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    33 cold shock, 4-day adult    28 heat shock, 4-day adult    72 Cadmium 50 mM 6 hrs, larvae L3  104 Cadmium 50 mM 12 hrs, larvae L3  (118) Cadmium 50 mM 48 hrs, 4-day adult    84 Cadmium 100 mM 48 hrs, 4-day adult    60 Copper 0.5 mM 12 hrs, larvae L3    46 Copper 15 mM 48 hrs, 4-day adult    49 Zinc 5 mM 12 hrs, larvae L3    47 Zinc 4.5 mM 48 hrs, 4-day adult    78 Ethanol 2.5% 3 hrs, larvae L3    48 Ethanol 5% 3 hrs, larvae L3  (162) Ethanol 10% 3 hrs, larvae L3    94 Caffeine 1.5 mg/ml 4 hrs, larvae L3  (125) Caffeine 2.5 mg/ml 48 hrs, 4-day adult    79 Caffeine 25 mg/ml 48 hrs, 4-day adult    24 Paraquat 5 mM 48 hrs, 4-day adult    69 Paraquat 10 mM 48 hrs, 4-day adult    56 Rotenone 2 μg 12 hrs, larvae L3  (133) Rotenone 8 μg 12 hrs, larvae L3    71 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    33 cold shock, 4-day adult    28 heat shock, 4-day adult    72 Cadmium 50 mM 6 hrs, larvae L3    104 Cadmium 50 mM 12 hrs, larvae L3    118 Cadmium 50 mM 48 hrs, 4-day adult    84 Cadmium 100 mM 48 hrs, 4-day adult    60 Copper 0.5 mM 12 hrs, larvae L3    46 Copper 15 mM 48 hrs, 4-day adult    49 Zinc 5 mM 12 hrs, larvae L3    47 Zinc 4.5 mM 48 hrs, 4-day adult    78 Ethanol 2.5% 3 hrs, larvae L3    48 Ethanol 5% 3 hrs, larvae L3    162 Ethanol 10% 3 hrs, larvae L3    94 Caffeine 1.5 mg/ml 4 hrs, larvae L3    125 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    79 Caffeine 25 mg/ml 48 hrs, 4-day adult    24 Paraquat 5 mM 48 hrs, 4-day adult    69 Paraquat 10 mM 48 hrs, 4-day adult    56 Rotenone 2 μg 12 hrs, larvae L3    133 Rotenone 8 μg 12 hrs, larvae L3    71 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    33 cold shock, 4-day adult    28 heat shock, 4-day adult    72 Cadmium 50 mM 6 hrs, larvae L3    104 Cadmium 50 mM 12 hrs, larvae L3    118 Cadmium 50 mM 48 hrs, 4-day adult    84 Cadmium 100 mM 48 hrs, 4-day adult    60 Copper 0.5 mM 12 hrs, larvae L3    46 Copper 15 mM 48 hrs, 4-day adult    49 Zinc 5 mM 12 hrs, larvae L3    47 Zinc 4.5 mM 48 hrs, 4-day adult    78 Ethanol 2.5% 3 hrs, larvae L3    48 Ethanol 5% 3 hrs, larvae L3    162 Ethanol 10% 3 hrs, larvae L3    94 Caffeine 1.5 mg/ml 4 hrs, larvae L3    125 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    79 Caffeine 25 mg/ml 48 hrs, 4-day adult    24 Paraquat 5 mM 48 hrs, 4-day adult    69 Paraquat 10 mM 48 hrs, 4-day adult    56 Rotenone 2 μg 12 hrs, larvae L3    133 Rotenone 8 μg 12 hrs, larvae L3    71 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult  (33) cold shock, 4-day adult  28 heat shock, 4-day adult  (72) Cadmium 50 mM 6 hrs, larvae L3  (104) Cadmium 50 mM 12 hrs, larvae L3  (118) Cadmium 50 mM 48 hrs, 4-day adult  (84) Cadmium 100 mM 48 hrs, 4-day adult  (60) Copper 0.5 mM 12 hrs, larvae L3  (46) Copper 15 mM 48 hrs, 4-day adult  (49) Zinc 5 mM 12 hrs, larvae L3  (47) Zinc 4.5 mM 48 hrs, 4-day adult  (78) Ethanol 2.5% 3 hrs, larvae L3  (48) Ethanol 5% 3 hrs, larvae L3  (162) Ethanol 10% 3 hrs, larvae L3  (94) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (125) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (79) Caffeine 25 mg/ml 48 hrs, 4-day adult    24 Paraquat 5 mM 48 hrs, 4-day adult  (69) Paraquat 10 mM 48 hrs, 4-day adult  (56) Rotenone 2 μg 12 hrs, larvae L3  (133) Rotenone 8 μg 12 hrs, larvae L3  (71) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    33 cold shock, 4-day adult    28 heat shock, 4-day adult    72 Cadmium 50 mM 6 hrs, larvae L3  104 Cadmium 50 mM 12 hrs, larvae L3  118 Cadmium 50 mM 48 hrs, 4-day adult    84 Cadmium 100 mM 48 hrs, 4-day adult    60 Copper 0.5 mM 12 hrs, larvae L3    46 Copper 15 mM 48 hrs, 4-day adult    49 Zinc 5 mM 12 hrs, larvae L3    47 Zinc 4.5 mM 48 hrs, 4-day adult    78 Ethanol 2.5% 3 hrs, larvae L3    48 Ethanol 5% 3 hrs, larvae L3  (162) Ethanol 10% 3 hrs, larvae L3    94 Caffeine 1.5 mg/ml 4 hrs, larvae L3  125 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    79 Caffeine 25 mg/ml 48 hrs, 4-day adult    24 Paraquat 5 mM 48 hrs, 4-day adult    69 Paraquat 10 mM 48 hrs, 4-day adult    56 Rotenone 2 μg 12 hrs, larvae L3  133 Rotenone 8 μg 12 hrs, larvae L3    71 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    33 cold shock, 4-day adult    28 heat shock, 4-day adult    72 Cadmium 50 mM 6 hrs, larvae L3    104 Cadmium 50 mM 12 hrs, larvae L3    118 Cadmium 50 mM 48 hrs, 4-day adult    84 Cadmium 100 mM 48 hrs, 4-day adult    60 Copper 0.5 mM 12 hrs, larvae L3    46 Copper 15 mM 48 hrs, 4-day adult    49 Zinc 5 mM 12 hrs, larvae L3    47 Zinc 4.5 mM 48 hrs, 4-day adult    78 Ethanol 2.5% 3 hrs, larvae L3    48 Ethanol 5% 3 hrs, larvae L3    162 Ethanol 10% 3 hrs, larvae L3    94 Caffeine 1.5 mg/ml 4 hrs, larvae L3    125 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    79 Caffeine 25 mg/ml 48 hrs, 4-day adult    24 Paraquat 5 mM 48 hrs, 4-day adult    69 Paraquat 10 mM 48 hrs, 4-day adult    56 Rotenone 2 μg 12 hrs, larvae L3    133 Rotenone 8 μg 12 hrs, larvae L3    71 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_10 mE1_20_mRNA_expression_cluster_15
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0036820 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG6852-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal CG6852GD10587 viable CG6852PL00166 Sterility Allele fertile CG6852PL00166 Other Phenotypes Allele neuroanatomy defective | larval stage CG6852GD10587 Phenotype manifest in Allele embryonic/larval neuroblast | larval stage CG6852GD10587 ganglion mother cell | larval stage CG6852GD10587
Classical Alleles ( 2 )
For All Classical Alleles Show
Allele of CG6852 Class Mutagen Stocks Known lesion CG6852G5581 P-element activity 1 -- CG6852PL00166 P-element activity 1 --
Alleles Carried on Transgenic Constructs ( 2 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG6852 Class Mutagen Stocks Known lesion CG6852GD10587 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG6852KK109090 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes
Aneuploid Aberrations
Disrupted in	Df(3l)Rad97-20 (Vanrobays et al., 2010) Df(3l)RRad97-8 (Vanrobays et al., 2010)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD10587} NA P{KK109090} NA
Insertions
	Type of insertions Name Expression data insertion of enhancer trap binary system PBac{GAL4D,EYFP}CG6852PL00166 No insertion of mobile activating element P{EP}CG6852G5581 NA
Gene Ontology: Function, Process & Cellular Component ( 4 unique terms )
Terms Based on Experimental Evidence ( 1 term )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
neurogenesis inferred from mutant phenotype (Neumüller et al., 2011)
Cellular Component ( 0 terms)
Terms Based on Predictions or Assertions ( 3 terms )
Molecular Function
CV term Evidence References
electron carrier activity inferred from electronic annotation with InterPro:IPR002109, InterPro:IPR011767 (FlyBase Curators et al., 2004-) protein disulfide oxidoreductase activity inferred from electronic annotation with InterPro:IPR002109 (FlyBase Curators et al., 2004-)
Biological Process
CV term Evidence References
cell redox homeostasis inferred from electronic annotation with InterPro:IPR002109, InterPro:IPR011767, InterPro:IPR011899 (FlyBase Curators et al., 2004-)
Cellular Component ( 0 terms)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
protein-protein
Interacting group Assay References
CG6852 - 14-3-3ζ anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6852 - Atx2 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6852 - CG10306 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6852 - CG11266 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6852 - CG11876 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6852 - CG15735 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6852 - CG17454 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6852 - CG4546 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6852 - CG5726 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6852 - CG6701 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6852 - CG6724 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6852 - CG7878 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6852 - Gp210 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6852 - Jupiter anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6852 - Prosα5 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6852 - Pxn anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6852 - R anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6852 - RpLP0 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6852 - Rs1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6852 - SC35 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6852 - SmG anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6852 - Srp54 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6852 - Syp anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6852 - Zn72D anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6852 - dream anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6852 - eEF1δ anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6852 - eIF3-S8 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6852 - eIF4AIII anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6852 - eIF6 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6852 - kst anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6852 - l(1)G0020 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6852 - mRpL15 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6852 - mRpL21 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6852 - mRpL42 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6852 - mRpL43 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6852 - mRpL50 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6852 - mRpL54 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6852 - mRpL9 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6852 - mRpS24 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6852 - nonA-l anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6852 - pic anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG6852 - sqh anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23)
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG6852 allele Gene References
External Data
Linkouts	DPiM - DPiM, Drosophila Protein interaction Map • FBgn0036820 DroID - A comprehensive database of gene and protein interactions. • FBgn0036820 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 40053
Orthologs
OrthoDB Orthologs (53) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6M0FNF Dipteran inclusive ortholog search EOG6XSM0H Insect inclusive ortholog search EOG60CGDZ Arthropod inclusive ortholog search EOG61NS40 Metazoa inclusive ortholog search EOG6742N4
Orthologs in Drosophila Species (EOG6M0FNF)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\CG6852     Drosophila simulans   Dsim\GD14776 Y   Drosophila sechellia   Dsec\GM14998 Y   Drosophila erecta   Dere\GG16009 Y   Drosophila yakuba   Dyak\GE23086     Drosophila yakuba   Dyak\GE19570 Y   Drosophila ananassae   Dana\GF23644 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA19906 Y   Drosophila persimilis   Dper\GL24885 Y   Drosophila willistoni   Dwil\GK20447 Y   Drosophila virilis   Dvir\GJ11844 Y   Drosophila mojavensis   Dmoj\GI13483 Y   Drosophila grimshawi   Dgri\GH14597 Y
Orthologs in non-Drosophila Dipterans (EOG6XSM0H)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL013980 Y Anopheles gambiae Malaria mosquito  Agam\GRX1 Y Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ009030 Y
Orthologs in non-Dipteran Insects (EOG60CGDZ)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\Grx1 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG002434 Y Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH15744 Y Atta cephalotes Leafcutter ant  Acep\ACEP22395 Y Camponotus floridanus Florida carpenter ant  Cflo\CFLO18855 Y Camponotus floridanus Florida carpenter ant  Cflo\CFLO18856 Y Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL17797 Y Linepithema humile Argentine ant  Lhum\LH22855 Y Pogonomyrmex barbatus Red harvester ant  Pbar\PB23848 Y Solenopsis invicta Red fire ant  Sinv\SINV15666 Y Acyrthosiphon pisum Pea aphid  Apim\ACYPI000233 Y Bombyx mori Silkmoth  Bmor\BGIBMGA008887 Y Pediculus humanus Human body louse  Phum\PHUM494790 Y Tribolium castaneum Red flour beetle  Tcas\TC005698 Y Tribolium castaneum Red flour beetle  Tcas\TC006382 Y
Orthologs in non-Insect Arthropods (EOG61NS40)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\JGI_V11_211823 Y Ixodes scapularis Deer tick  Isca\ISCW020750 Y
Orthologs in non-Arthropod Metazoa (EOG6742N4)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Caenorhabditis elegans Nematode  Cele\glrx-21 Y Caenorhabditis elegans Nematode  Cele\glrx-10 Y Caenorhabditis elegans Nematode  Cele\F10D7.3 Y Caenorhabditis elegans Nematode  Cele\glrx-22 Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_021128gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_020292gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_006882gn Y Danio rerio Zebrafish  Drer\glrx Y Danio rerio Zebrafish  Drer\glrx2 Y Xenopus tropicalis Western clawed frog  Xtro\glrx2 Y Xenopus tropicalis Western clawed frog  Xtro\glrx Y Gallus gallus Domestic chicken  Ggal\GLRX Y Gallus gallus Domestic chicken  Ggal\GLRX2 Y Mus musculus House mouse  Mmus\Glrx Y Mus musculus House mouse  Mmus\Glrx2 Y Rattus norvegicus Norway rat  Rnor\Glrx2 Y Rattus norvegicus Norway rat  Rnor\Glrx Y Rattus norvegicus Norway rat  Rnor\ENSRNOG00000040025 Y Homo sapiens Human  Hsap\GLRX2 Y Homo sapiens Human  Hsap\GLRX Y
Human Orthologs (2)
Gene OMIM HGNC Hsap\GLRX2     Hsap\GLRX
AAA Orthologs (11) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD14776 Drosophila sechellia Dsec\GM14998 Drosophila erecta Dere\GG16009 Drosophila yakuba Dyak\GE19570 Drosophila ananassae Dana\GF23644 Drosophila pseudoobscura pseudoobscura Dpse\GA19906 Drosophila persimilis Dper\GL24885 Drosophila willistoni Dwil\GK20447 Drosophila virilis Dvir\GJ11844 Drosophila mojavensis Dmoj\GI13483 Drosophila grimshawi Dgri\GH14597
Stocks & Reagents
Stocks Listed in FlyBase ( 4 )
Bloomington	33268 w1118; P{EP}CG6852G5581 P{EP}G5581 19405 w*; PBac{GAL4D,EYFP}CG6852PL00166 P{FRT(whs)}2A P{neoFRT}82B
VDRC	v101410 P{KK109090}VIE-260B v26001 w1118; P{GD10587}v26001
Genomic Clones ( 1 )
	BACR48N04 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 5 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	GH24739
Other clones	DPiM_GH24739
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones
Other clones	Dmel_dig_013534_0674_2779 IP03459 IP03559
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0036820 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 40053
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of	Source for merge of: CG6852 BcDNA:GH24739 (FlyBase, 1996-)
Additional comments	Source for merge of CG6852 BcDNA:GH24739 was a shared cDNA (date:030728). (FlyBase, 1996-)
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_140808 NM_001259898 RefSeq (Proteins) • NP_649065 NP_001246827 DDBJ / EMBL / GenBank • AAF49222 AAM50679 ACL83323 AFH04498 AI404887 AY118819 Entrez Gene - A searchable database of RefSeq genes. • 40053 UniProtKB/TrEMBL • B7Z076 Q9VVT6
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Glutaredoxin (IPR002109) Glutaredoxin, eukaryotic/virial (IPR011899) Thioredoxin-like fold (IPR012336) Glutaredoxin subgroup (IPR014025) Glutaredoxin active site (IPR011767)
Linkouts
	DPiM - DPiM, Drosophila Protein interaction Map • FBgn0036820 DroID - A comprehensive database of gene and protein interactions. • FBgn0036820 DRSC - Results from RNAi screens. • FBgn0036820 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0036820 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG6852-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0036820 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 40053 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 40053 modMine - Data generated by the modENCODE project. • FBgn0036820
Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	BcDNA:GH24739   CG6852 (Quinones-Coello, 2007, Vanrobays et al., 2010, Guan et al., 2011, Keleman et al., 2009.8.5, Dierick and Greenspan, 2006, Betz and Darnell, 2006, Scherzer et al., 2003)
Name Synonym
Secondary FlyBase IDs
	FBgn0063224
References ( 19 )
Research paper	Díaz-Castillo and Ranz, 2012, Mol. Biol. Evol. 29(9): 2105--2108 Nuclear chromosome dynamics in the Drosophila male germ line contribute to the nonrandom genomic distribution of retrogenes. [FBrf0219274] Guan et al., 2011, Learn. Mem. 18(4): 191--206 Altered gene regulation and synaptic morphology in Drosophila learning and memory mutants. [FBrf0213277] Vanrobays et al., 2010, BioTechniques 48(1): 53--60 Identification and mapping of induced chromosomal deletions using sequence polymorphisms. [FBrf0209758] Dierick and Greenspan, 2006, Nat. Genet. 38(9): 1023--1031 Molecular analysis of flies selected for aggressive behavior. [FBrf0195365] Scherzer et al., 2003, Hum. Mol. Genet. 12(19): 2457--2466 Gene expression changes presage neurodegeneration in a Drosophila model of Parkinson's disease. [FBrf0162171]
Supplementary material	Graveley et al., 2011, Nature 471(7339): Supplementary Table 33. Fuzzy Cluster Members. [FBrf0213980] Neumüller et al., 2011, Cell Stem Cell 8(5): Supplemental Table S1. [FBrf0214431] The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Quinones-Coello, 2007, Genetics 175(3): Supplemental Table 1. List of genes associated with protein or enhancer traps. [FBrf0200393]
Review	Betz and Darnell, 2006, Nat. Genet. 38(9): 977--979 A Hopscotch-chromatin connection. [FBrf0194436]
Personal communication to FlyBase	Bellen, 2010.12.22, GE836.xml GE836.xml [FBrf0212684] Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510] Mintseris et al., 2009.11.23, DPiM: the Drosophila Protein Interaction Mapping project DPiM: the Drosophila Protein Interaction Mapping project [FBrf0209452] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] FlyBase Curators et al., 2004-, Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. [FBrf0174215] Haecker et al., 2004, Haecker insertions. Haecker insertions. [FBrf0184338] Gene Disruption Project members, 2001-, (Computer file) (Computer file) [FBrf0132177] BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. (Computer file) Berkeley Drosophila Genome Project. (Computer file) [FBrf0125078]
FlyBase analysis	FlyBase, 1996-, FlyBase inference based on genome sequence analysis. FlyBase inference based on genome sequence analysis. [FBrf0104946]