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Gene Dmel\CG4858

General Information
Symbol	Dmel\CG4858	Species	D. melanogaster
Name		Annotation symbol	CG4858
Feature type	protein_coding_gene	FlyBase ID	FBgn0037011
Gene Model Status	Current	Stock availability	3 publicly available
Genomic Location
Chromosome (arm)	3L	Recombination map
Cytogenetic map	77C7-77C7	Sequence location	3L:20,519,697..20,521,010 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG4858 (FBgn0037011). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: nucleotide binding. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: ATPase-like, ParA/MinD; Mrp, conserved site. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 06-12 hour embryonic stages. Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult tissues/organs expressed at moderate levels. Expression at high levels in the following post-embryonic organs or tissues: adult hindgut, larval/adult Malpighian tubules, larval fat body. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval hindgut, adult heart, adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male accessory gland, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1625315_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG4858. Gene sequence location is 3L:20519697..20521010.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2011_10
FB2012_01	Sequence features BKN20445 HFA11758
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 77C7-77C7   Limits computationally determined from genome sequence between P{EP}trblEP3519 and P{EP}fngEP3082&P{lacW}skdL7062
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG4858 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG4858-RA FBtr0078210  NM_140986   929   260
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG4858-PA   FBpp0077868   28.2   260   4.95     NP_649243   AAF51623
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Mrp, conserved site (IPR000808) ATPase-like, ParA/MinD (IPR019591)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE014296 AAF51623   BT012307   CO154908   CO316659   EC265627   EV575192   GH941701
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9VPD2
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0037011    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0037011 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 06-12 hour embryonic stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0037011 expression level Developmental Stage   Expression Level embryo 00-02hr    1169 embryo 02-04hr    1818 embryo 04-06hr    2973 embryo 06-08hr    2388 embryo 08-10hr    2470 embryo 10-12hr    4294 embryo 12-14hr    2276 embryo 14-16hr    2573 embryo 16-18hr    2384 embryo 18-20hr    2187 embryo 20-22hr    1747 embryo 22-24hr    2050 larva L1    2781 larva L2    2640 larva L3 12hr old    2662 larva L3 puffstage 1-2    2711 larva L3 puffstage 3-6    2705 larva L3 puffstage 7-9    3195 white prepupae new    2928 white prepupae 12hr    1977 white prepupae 24hr    2172 pupae 2d postWPP    2092 pupae 3d postWPP    1928 pupae 4d postWPP    2216 adult male 01day    1930 adult male 05day    2289 adult male 30day    2943 adult female 01day    2987 adult female 05day    2345 adult female 30day    2776 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (1169) embryo 02-04hr  (1818) embryo 04-06hr  (2973) embryo 06-08hr  (2388) embryo 08-10hr  (2470) embryo 10-12hr  (4294) embryo 12-14hr  (2276) embryo 14-16hr  (2573) embryo 16-18hr  (2384) embryo 18-20hr  (2187) embryo 20-22hr  (1747) embryo 22-24hr  (2050) larva L1  (2781) larva L2  (2640) larva L3 12hr old  (2662) larva L3 puffstage 1-2  (2711) larva L3 puffstage 3-6  (2705) larva L3 puffstage 7-9  (3195) white prepupae new  (2928) white prepupae 12hr  (1977) white prepupae 24hr  (2172) pupae 2d postWPP  (2092) pupae 3d postWPP  (1928) pupae 4d postWPP  (2216) adult male 01day  (1930) adult male 05day  (2289) adult male 30day  (2943) adult female 01day  (2987) adult female 05day  (2345) adult female 30day  (2776) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    1169 embryo 02-04hr  (1818) embryo 04-06hr  (2973) embryo 06-08hr  (2388) embryo 08-10hr  (2470) embryo 10-12hr  (4294) embryo 12-14hr  (2276) embryo 14-16hr  (2573) embryo 16-18hr  (2384) embryo 18-20hr  (2187) embryo 20-22hr  (1747) embryo 22-24hr  (2050) larva L1  (2781) larva L2  (2640) larva L3 12hr old  (2662) larva L3 puffstage 1-2  (2711) larva L3 puffstage 3-6  (2705) larva L3 puffstage 7-9  (3195) white prepupae new  (2928) white prepupae 12hr  (1977) white prepupae 24hr  (2172) pupae 2d postWPP  (2092) pupae 3d postWPP  (1928) pupae 4d postWPP  (2216) adult male 01day  (1930) adult male 05day  (2289) adult male 30day  (2943) adult female 01day  (2987) adult female 05day  (2345) adult female 30day  (2776) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    1169 embryo 02-04hr    1818 embryo 04-06hr    2973 embryo 06-08hr    2388 embryo 08-10hr    2470 embryo 10-12hr    4294 embryo 12-14hr    2276 embryo 14-16hr    2573 embryo 16-18hr    2384 embryo 18-20hr    2187 embryo 20-22hr    1747 embryo 22-24hr    2050 larva L1    2781 larva L2    2640 larva L3 12hr old    2662 larva L3 puffstage 1-2    2711 larva L3 puffstage 3-6    2705 larva L3 puffstage 7-9    3195 white prepupae new    2928 white prepupae 12hr    1977 white prepupae 24hr    2172 pupae 2d postWPP    2092 pupae 3d postWPP    1928 pupae 4d postWPP    2216 adult male 01day    1930 adult male 05day    2289 adult male 30day    2943 adult female 01day    2987 adult female 05day    2345 adult female 30day    2776 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    1169 embryo 02-04hr    1818 embryo 04-06hr    2973 embryo 06-08hr    2388 embryo 08-10hr    2470 embryo 10-12hr    4294 embryo 12-14hr    2276 embryo 14-16hr    2573 embryo 16-18hr    2384 embryo 18-20hr    2187 embryo 20-22hr    1747 embryo 22-24hr    2050 larva L1    2781 larva L2    2640 larva L3 12hr old    2662 larva L3 puffstage 1-2    2711 larva L3 puffstage 3-6    2705 larva L3 puffstage 7-9    3195 white prepupae new    2928 white prepupae 12hr    1977 white prepupae 24hr    2172 pupae 2d postWPP    2092 pupae 3d postWPP    1928 pupae 4d postWPP    2216 adult male 01day    1930 adult male 05day    2289 adult male 30day    2943 adult female 01day    2987 adult female 05day    2345 adult female 30day    2776 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0037011 expression level Developmental Stage   Expression Level embryo 00-02hr    1169 embryo 02-04hr    1818 embryo 04-06hr    2973 embryo 06-08hr    2388 embryo 08-10hr    2470 embryo 10-12hr    4294 embryo 12-14hr    2276 embryo 14-16hr    2573 embryo 16-18hr    2384 embryo 18-20hr    2187 embryo 20-22hr    1747 embryo 22-24hr    2050 larva L1    2781 larva L2    2640 larva L3 12hr old    2662 larva L3 puffstage 1-2    2711 larva L3 puffstage 3-6    2705 larva L3 puffstage 7-9    3195 white prepupae new    2928 white prepupae 12hr    1977 white prepupae 24hr    2172 pupae 2d postWPP    2092 pupae 3d postWPP    1928 pupae 4d postWPP    2216 adult male 01day    1930 adult male 05day    2289 adult male 30day    2943 adult female 01day    2987 adult female 05day    2345 adult female 30day    2776 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (1169) embryo 02-04hr  (1818) embryo 04-06hr  (2973) embryo 06-08hr  (2388) embryo 08-10hr  (2470) embryo 10-12hr  (4294) embryo 12-14hr  (2276) embryo 14-16hr  (2573) embryo 16-18hr  (2384) embryo 18-20hr  (2187) embryo 20-22hr  (1747) embryo 22-24hr  (2050) larva L1  (2781) larva L2  (2640) larva L3 12hr old  (2662) larva L3 puffstage 1-2  (2711) larva L3 puffstage 3-6  (2705) larva L3 puffstage 7-9  (3195) white prepupae new  (2928) white prepupae 12hr  (1977) white prepupae 24hr  (2172) pupae 2d postWPP  (2092) pupae 3d postWPP  (1928) pupae 4d postWPP  (2216) adult male 01day  (1930) adult male 05day  (2289) adult male 30day  (2943) adult female 01day  (2987) adult female 05day  (2345) adult female 30day  (2776) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    1169 embryo 02-04hr  1818 embryo 04-06hr  (2973) embryo 06-08hr  2388 embryo 08-10hr  2470 embryo 10-12hr  (4294) embryo 12-14hr  2276 embryo 14-16hr  (2573) embryo 16-18hr  2384 embryo 18-20hr  2187 embryo 20-22hr  1747 embryo 22-24hr  2050 larva L1  (2781) larva L2  (2640) larva L3 12hr old  (2662) larva L3 puffstage 1-2  (2711) larva L3 puffstage 3-6  (2705) larva L3 puffstage 7-9  (3195) white prepupae new  (2928) white prepupae 12hr  1977 white prepupae 24hr  2172 pupae 2d postWPP  2092 pupae 3d postWPP  1928 pupae 4d postWPP  2216 adult male 01day  1930 adult male 05day  2289 adult male 30day  (2943) adult female 01day  (2987) adult female 05day  2345 adult female 30day  (2776) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    1169 embryo 02-04hr    1818 embryo 04-06hr    2973 embryo 06-08hr    2388 embryo 08-10hr    2470 embryo 10-12hr    4294 embryo 12-14hr    2276 embryo 14-16hr    2573 embryo 16-18hr    2384 embryo 18-20hr    2187 embryo 20-22hr    1747 embryo 22-24hr    2050 larva L1    2781 larva L2    2640 larva L3 12hr old    2662 larva L3 puffstage 1-2    2711 larva L3 puffstage 3-6    2705 larva L3 puffstage 7-9    3195 white prepupae new    2928 white prepupae 12hr    1977 white prepupae 24hr    2172 pupae 2d postWPP    2092 pupae 3d postWPP    1928 pupae 4d postWPP    2216 adult male 01day    1930 adult male 05day    2289 adult male 30day    2943 adult female 01day    2987 adult female 05day    2345 adult female 30day    2776 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    1169 embryo 02-04hr    1818 embryo 04-06hr    2973 embryo 06-08hr    2388 embryo 08-10hr    2470 embryo 10-12hr    4294 embryo 12-14hr    2276 embryo 14-16hr    2573 embryo 16-18hr    2384 embryo 18-20hr    2187 embryo 20-22hr    1747 embryo 22-24hr    2050 larva L1    2781 larva L2    2640 larva L3 12hr old    2662 larva L3 puffstage 1-2    2711 larva L3 puffstage 3-6    2705 larva L3 puffstage 7-9    3195 white prepupae new    2928 white prepupae 12hr    1977 white prepupae 24hr    2172 pupae 2d postWPP    2092 pupae 3d postWPP    1928 pupae 4d postWPP    2216 adult male 01day    1930 adult male 05day    2289 adult male 30day    2943 adult female 01day    2987 adult female 05day    2345 adult female 30day    2776 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0037011    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0037011 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult tissues/organs expressed at moderate levels. Expression at high levels in the following post-embryonic organs or tissues: adult hindgut, larval/adult Malpighian tubules, larval fat body. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval hindgut, adult heart, adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male accessory gland, larval/adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0037011 expression level Tissue   Expression Level Larval Central Nervous System    217.975 Larval Midgut    222.8 Larval Hindgut    232.5 Larval Malpighian Tubules    504 Larval Fat Body    565.1 Larval Salivary Gland    355.4 Larval Trachea    384.45 Larval Carcass    254.8 Adult Head    296.4 Adult Eye    459.9 Adult Brain    192.5 Adult Thoracic-Abdominal Ganglion    198.6 Adult Crop    310.6 Adult Midgut    305.7 Adult Hindgut    513.4 Adult Malpighian Tubules    588.8 Adult Fat Body    389.5 Adult Salivary Gland    493.6 Adult Heart    410.325 Adult VirginFemale Spermatheca    447.1 Adult InseminatedFemale Spermatheca    438.8 Adult Ovary    194.8 Adult Testis    55.5 Adult Male Accessory Gland    392.1 Adult Carcass    322.6 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    217.975 Larval Midgut    222.8 Larval Hindgut    232.5 Larval Malpighian Tubules  504 Larval Fat Body  (565.1) Larval Salivary Gland    355.4 Larval Trachea    384.45 Larval Carcass    254.8 Adult Head    296.4 Adult Eye    459.9 Adult Brain    192.5 Adult Thoracic-Abdominal Ganglion    198.6 Adult Crop    310.6 Adult Midgut    305.7 Adult Hindgut  513.4 Adult Malpighian Tubules  (588.8) Adult Fat Body    389.5 Adult Salivary Gland    493.6 Adult Heart    410.325 Adult VirginFemale Spermatheca    447.1 Adult InseminatedFemale Spermatheca    438.8 Adult Ovary    194.8 Adult Testis    55.5 Adult Male Accessory Gland    392.1 Adult Carcass    322.6 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    217.975 Larval Midgut    222.8 Larval Hindgut    232.5 Larval Malpighian Tubules    504 Larval Fat Body    565.1 Larval Salivary Gland    355.4 Larval Trachea    384.45 Larval Carcass    254.8 Adult Head    296.4 Adult Eye    459.9 Adult Brain    192.5 Adult Thoracic-Abdominal Ganglion    198.6 Adult Crop    310.6 Adult Midgut    305.7 Adult Hindgut    513.4 Adult Malpighian Tubules    588.8 Adult Fat Body    389.5 Adult Salivary Gland    493.6 Adult Heart    410.325 Adult VirginFemale Spermatheca    447.1 Adult InseminatedFemale Spermatheca    438.8 Adult Ovary    194.8 Adult Testis    55.5 Adult Male Accessory Gland    392.1 Adult Carcass    322.6 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    217.975 Larval Midgut    222.8 Larval Hindgut    232.5 Larval Malpighian Tubules    504 Larval Fat Body    565.1 Larval Salivary Gland    355.4 Larval Trachea    384.45 Larval Carcass    254.8 Adult Head    296.4 Adult Eye    459.9 Adult Brain    192.5 Adult Thoracic-Abdominal Ganglion    198.6 Adult Crop    310.6 Adult Midgut    305.7 Adult Hindgut    513.4 Adult Malpighian Tubules    588.8 Adult Fat Body    389.5 Adult Salivary Gland    493.6 Adult Heart    410.325 Adult VirginFemale Spermatheca    447.1 Adult InseminatedFemale Spermatheca    438.8 Adult Ovary    194.8 Adult Testis    55.5 Adult Male Accessory Gland    392.1 Adult Carcass    322.6 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0037011 expression level Tissue   Expression Level Larval Central Nervous System    217.975 Larval Midgut    222.8 Larval Hindgut    232.5 Larval Malpighian Tubules    504 Larval Fat Body    565.1 Larval Salivary Gland    355.4 Larval Trachea    384.45 Larval Carcass    254.8 Adult Head    296.4 Adult Eye    459.9 Adult Brain    192.5 Adult Thoracic-Abdominal Ganglion    198.6 Adult Crop    310.6 Adult Midgut    305.7 Adult Hindgut    513.4 Adult Malpighian Tubules    588.8 Adult Fat Body    389.5 Adult Salivary Gland    493.6 Adult Heart    410.325 Adult VirginFemale Spermatheca    447.1 Adult InseminatedFemale Spermatheca    438.8 Adult Ovary    194.8 Adult Testis    55.5 Adult Male Accessory Gland    392.1 Adult Carcass    322.6 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    217.975 Larval Midgut    222.8 Larval Hindgut    232.5 Larval Malpighian Tubules  504 Larval Fat Body  565.1 Larval Salivary Gland    355.4 Larval Trachea    384.45 Larval Carcass    254.8 Adult Head    296.4 Adult Eye    459.9 Adult Brain    192.5 Adult Thoracic-Abdominal Ganglion    198.6 Adult Crop    310.6 Adult Midgut    305.7 Adult Hindgut  513.4 Adult Malpighian Tubules  588.8 Adult Fat Body    389.5 Adult Salivary Gland    493.6 Adult Heart    410.325 Adult VirginFemale Spermatheca    447.1 Adult InseminatedFemale Spermatheca    438.8 Adult Ovary    194.8 Adult Testis    55.5 Adult Male Accessory Gland    392.1 Adult Carcass    322.6 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    217.975 Larval Midgut    222.8 Larval Hindgut    232.5 Larval Malpighian Tubules    504 Larval Fat Body    565.1 Larval Salivary Gland    355.4 Larval Trachea    384.45 Larval Carcass    254.8 Adult Head    296.4 Adult Eye    459.9 Adult Brain    192.5 Adult Thoracic-Abdominal Ganglion    198.6 Adult Crop    310.6 Adult Midgut    305.7 Adult Hindgut    513.4 Adult Malpighian Tubules    588.8 Adult Fat Body    389.5 Adult Salivary Gland    493.6 Adult Heart    410.325 Adult VirginFemale Spermatheca    447.1 Adult InseminatedFemale Spermatheca    438.8 Adult Ovary    194.8 Adult Testis    55.5 Adult Male Accessory Gland    392.1 Adult Carcass    322.6 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    217.975 Larval Midgut    222.8 Larval Hindgut    232.5 Larval Malpighian Tubules    504 Larval Fat Body    565.1 Larval Salivary Gland    355.4 Larval Trachea    384.45 Larval Carcass    254.8 Adult Head    296.4 Adult Eye    459.9 Adult Brain    192.5 Adult Thoracic-Abdominal Ganglion    198.6 Adult Crop    310.6 Adult Midgut    305.7 Adult Hindgut    513.4 Adult Malpighian Tubules    588.8 Adult Fat Body    389.5 Adult Salivary Gland    493.6 Adult Heart    410.325 Adult VirginFemale Spermatheca    447.1 Adult InseminatedFemale Spermatheca    438.8 Adult Ovary    194.8 Adult Testis    55.5 Adult Male Accessory Gland    392.1 Adult Carcass    322.6 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    296.4   NA  Eye    459.9   NA  Brain    192.5   217.975  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    198.6   NA  Crop    310.6   222.8  Midgut    305.7   232.5  Hindgut    513.4   504  Malpighian Tubules    588.8   565.1  Fat Body    389.5   355.4  Salivary Gland    493.6   NA  Heart    410.325   384.45  Trachea    NA   NA  VirginFemale Spermatheca    447.1   NA  InseminatedFemale Spermatheca    438.8   NA  Ovary    194.8   NA  Testis    55.5   NA  Male Accessory Gland    392.1   254.8  Carcass    322.6 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_09
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0037011 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG4858-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable, with Scer\GAL4pnr-MD237 CG4858GD11450 Phenotype manifest in Allele
Classical Alleles ( 1 )
For All Classical Alleles Show
Allele of CG4858 Class Mutagen Stocks Known lesion CG4858d00793 1 --
Alleles Carried on Transgenic Constructs ( 2 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG4858 Class Mutagen Stocks Known lesion CG4858GD11450 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG4858KK100349 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD11450} NA P{KK100349} NA
Insertions
	Type of insertions Name Expression data insertion of mobile activating element P{XP}CG4858d00793 NA
Gene Ontology: Function, Process & Cellular Component ( 2 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 2 terms )
Molecular Function
CV term Evidence References
ATP binding inferred from electronic annotation with InterPro:IPR000808 (FlyBase Curators et al., 2004-) nucleotide binding inferred from sequence or structural similarity with NCBI_gi:4505337 (FlyBase, 1992-)
Biological Process ( 0 terms)
Cellular Component ( 0 terms)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG4858 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 65539 DroID - A comprehensive database of gene and protein interactions. • FBgn0037011 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 40282
Orthologs
Genome-wide drosophilid orthologs	Dana\GF10354 Dere\GG16127 Dgri\GH14587 Dmoj\GI13405 Dper\GL12799 Dpse\GA18483 Dsec\GM22307 Dsim\GD14899 Dvir\GJ11530 Dwil\GK12055 Dyak\GE23241
Curated drosophilid orthologs	Dpse\GA18483
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL008143-PA Aedes aegypti (mosquito) AAEL014154-PA Aedes aegypti (mosquito) AGAP010873-PA Anopheles gambiae (mosquito) XP_393995.1 Apis mellifera (honey bee) XP_001948297.1 Acyrthosiphon pisum (pea aphid) 275293 Branchiostoma floridae (lancelet) 64618 Branchiostoma floridae (lancelet) BGIBMGA006973-PA Bombyx mori (silk worm) ENSBTAP00000022029 Bos taurus (bovine) CAL0003944 Candida albicans (a form of yeast) ENSCAFP00000028825 Canis familiaris (dog) CAGL0J02112g Candida glabrata (haploid yeast) ENSCINP00000007293 Ciona intestinalis (sea squirt) CPIJ017390 Culex pipens (mosquito) ENSCPOP00000007257 Cavia porcellus (guinea pig) ENSCSAVP00000006775 Ciona savignyi (sedentary tunicate) 152351 Capitella spl (polychaete worm) DDB0232414 Dictyostelium discoideum (amoeba) DEHA2B09416g Debaryomyces Hansenii (yeast) 230298 Daphnia pulex (daphnia) ENSDARP00000072510 Danio rerio (zebra fish) XP_653192 Entamoeba histolytica (anaerobic protozoan) ENSGACP00000011010 Gymnopilus aculeatus (mushroom) ENSGALP00000003634 Gallus gallus (chicken) 157680 Hypsipyla robusta (cedar shoot borer) ENSP00000262302 Homo sapiens (human) ISCW002788-PA Ixodes scapularis (deer tick) KLLA0D13970g Kluyveromyces lactis (yeast) 229501 Lottia gigantea (owl limpet) LmjF26.0430 Leishmania major (virus) 33756 Monocosta brevicollis (choanoflagellate) ENSMODP00000020131 Monodelphis domestica (gray opossum) ENSMMUP00000024466 Macaca mulatta (rhesus monkey) ENSMUSP00000049319 Mus musculus (house mouse) 229988 Nematostella vectensis (starlet anemone) XP_001607113.1 Nasonia vitripennis (wasp) ENSOANP00000003422 Ornithorynchus anatinus (platypus) ENSORLP00000009063 Oryzias latipes (japanese killifish) PHUM004221-PA Pediculus humanus (human body louse) ENSPPYP00000007885 Pongo pygmaeus (orangutan) ENSPTRP00000013005 Pan troglodytes (chimpanzee) ENSRNOP00000020504 Rattus norvegicus (norway rat) YIL003W Saccharomyces cerevisiae (budding yeast) Smp_154750 Schistosoma mansoni (trematode parasite) 53697 Trichoplax adhaerens (metazoa) XP_972387.1 Tribolium castaneum (red flour beetle) Tc00.1047053503579.100 Trypanosoma cruzi (parasitic trypanosome) ENSTNIP00000015775 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000037172 Takifugu rubripes (pufferfish Takifugu) ENSXETP00000022766 Xenopus tropicalis (frog) YALI0E19074g Yarrowia lipolytica (nonconventional yeast) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB18117 NV13710 LH15365 ISCW002788 FBgn0240440 FBgn0237030 FBgn0214066 FBgn0198788 FBgn0186571 FBgn0177177 JGI_V11_230298 FBgn0078485 FBgn0150405 FBgn0136162 FBgn0122063 FBgn0108362 FBgn0087395 CPIJ017390 BGIBMGA006973 ACYPI001484 GB17553 AGAP012788 AGAP010873 AAEL014154 AAEL008143 PHUM060670 GLEAN_05845
Stocks & Reagents
Stocks Listed in FlyBase ( 3 )
Harvard	- P{XP}CG4858d00793
VDRC	v106917 P{KK100349}VIE-260B v26649 w1118 P{GD11450}v26649
Genomic Clones ( 2 )
	BACR02B14 BACR21J02 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 6 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	LP21185
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones
Other clones	524241 Dmel_dig_000404_0641_0296 EK265603 EN05020 RP004263234
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0037011 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 40282
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_140986 RefSeq (Proteins) • NP_649243 DDBJ / EMBL / GenBank • AAF51623 Entrez Gene - A searchable database of RefSeq genes. • 40282 UniProtKB/TrEMBL • Q9VPD2
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Mrp, conserved site (IPR000808) ATPase-like, ParA/MinD (IPR019591)
Linkouts
	BioGRID - A database of protein and genetic interactions • 65539 DroID - A comprehensive database of gene and protein interactions. • FBgn0037011 DRSC - Results from RNAi screens. • FBgn0037011 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0037011 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG4858-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0037011 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 40282 InParanoid A subset of ortholog calls from InParanoid. • AAEL008143-PA Aedes aegypti (mosquito) AAEL014154-PA Aedes aegypti (mosquito) AGAP010873-PA Anopheles gambiae (mosquito) XP_393995.1 Apis mellifera (honey bee) XP_001948297.1 Acyrthosiphon pisum (pea aphid) 275293 Branchiostoma floridae (lancelet) 64618 Branchiostoma floridae (lancelet) BGIBMGA006973-PA Bombyx mori (silk worm) ENSBTAP00000022029 Bos taurus (bovine) CAL0003944 Candida albicans (a form of yeast) ENSCAFP00000028825 Canis familiaris (dog) CAGL0J02112g Candida glabrata (haploid yeast) ENSCINP00000007293 Ciona intestinalis (sea squirt) CPIJ017390 Culex pipens (mosquito) ENSCPOP00000007257 Cavia porcellus (guinea pig) ENSCSAVP00000006775 Ciona savignyi (sedentary tunicate) 152351 Capitella spl (polychaete worm) DDB0232414 Dictyostelium discoideum (amoeba) DEHA2B09416g Debaryomyces Hansenii (yeast) 230298 Daphnia pulex (daphnia) ENSDARP00000072510 Danio rerio (zebra fish) XP_653192 Entamoeba histolytica (anaerobic protozoan) ENSGACP00000011010 Gymnopilus aculeatus (mushroom) ENSGALP00000003634 Gallus gallus (chicken) 157680 Hypsipyla robusta (cedar shoot borer) ENSP00000262302 Homo sapiens (human) ISCW002788-PA Ixodes scapularis (deer tick) KLLA0D13970g Kluyveromyces lactis (yeast) 229501 Lottia gigantea (owl limpet) LmjF26.0430 Leishmania major (virus) 33756 Monocosta brevicollis (choanoflagellate) ENSMODP00000020131 Monodelphis domestica (gray opossum) ENSMMUP00000024466 Macaca mulatta (rhesus monkey) ENSMUSP00000049319 Mus musculus (house mouse) 229988 Nematostella vectensis (starlet anemone) XP_001607113.1 Nasonia vitripennis (wasp) ENSOANP00000003422 Ornithorynchus anatinus (platypus) ENSORLP00000009063 Oryzias latipes (japanese killifish) PHUM004221-PA Pediculus humanus (human body louse) ENSPPYP00000007885 Pongo pygmaeus (orangutan) ENSPTRP00000013005 Pan troglodytes (chimpanzee) ENSRNOP00000020504 Rattus norvegicus (norway rat) YIL003W Saccharomyces cerevisiae (budding yeast) Smp_154750 Schistosoma mansoni (trematode parasite) 53697 Trichoplax adhaerens (metazoa) XP_972387.1 Tribolium castaneum (red flour beetle) Tc00.1047053503579.100 Trypanosoma cruzi (parasitic trypanosome) ENSTNIP00000015775 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000037172 Takifugu rubripes (pufferfish Takifugu) ENSXETP00000022766 Xenopus tropicalis (frog) YALI0E19074g Yarrowia lipolytica (nonconventional yeast) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 40282 modMine - Data generated by the modENCODE project. • FBgn0037011 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB18117 NV13710 LH15365 ISCW002788 FBgn0240440 FBgn0237030 FBgn0214066 FBgn0198788 FBgn0186571 FBgn0177177 JGI_V11_230298 FBgn0078485 FBgn0150405 FBgn0136162 FBgn0122063 FBgn0108362 FBgn0087395 CPIJ017390 BGIBMGA006973 ACYPI001484 GB17553 AGAP012788 AGAP010873 AAEL014154 AAEL008143 PHUM060670 GLEAN_05845
Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	CG4858 (Keleman et al., 2009.8.5, Zimmerman, 2010.12.1)
Name Synonym
Secondary FlyBase IDs
References ( 11 )
Supplementary material	The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518] Giot et al., 2003, Science 302(5651): Tables S1 to S7. [FBrf0166452]
Personal communication to FlyBase	Zimmerman, 2010.12.1, Sequencing of the Gal4c415 insertion site. Sequencing of the Gal4c415 insertion site. [FBrf0212436] Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] FlyBase Curators et al., 2004-, Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. [FBrf0174215]
FlyBase analysis	FlyBase Curators, 2008, Insertion identifiers and alleles based on genomic location of insertions with respect to gene annotations. Insertion identifiers and alleles based on genomic location of insertions with respect to gene annotations. [FBrf0202955] FlyBase, 1992-, FlyBase curation FlyBase curation. [FBrf0105495]
Computer file	BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. Berkeley Drosophila Genome Project. [FBrf0125078]