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Gene Dmel\CG10585

General Information
Symbol	Dmel\CG10585	Species	D. melanogaster
Name		Annotation symbol	CG10585
Feature type	protein_coding_gene	FlyBase ID	FBgn0037044
Gene Model Status	Current	Stock availability	5 publicly available
Genomic Location
Chromosome (arm)	3L	Recombination map
Cytogenetic map	78A2-78A2	Sequence location	3L:21,020,995..21,023,241 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG10585 (FBgn0037044). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: trans-hexaprenyltranstransferase activity. The biological processes in which it is involved are not known. 6 alleles are reported. The phenotype of these alleles is annotated with: mesothoracic tergum. It has one annotated transcript and one annotated polypeptide. Protein features are: Polyprenyl synthetase-related; Terpenoid synthase. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of low expression. Peak expression observed within 12-18 embryonic stages. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: larval/adult central nervous system, adult crop, larval/adult hindgut, larval salivary gland, larval trachea, adult ovary. Comments on Affy2 ProbeSet: ProbeSet 1623664_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG10585. Gene sequence location is 3L:21020995..21023241.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2011_10
FB2012_01	Sequence features BKN22531 HFA11625
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 78A2-78A2   Limits computationally determined from genome sequence between P{EP}fngEP3082&P{lacW}skdL7062 and P{lacW}l(3)L5541L5541
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG10585 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG10585-RA FBtr0078287  NM_141020   2010   448
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG10585-PA   FBpp0077945   49.4   448   6.80     NP_649277   AAF51668
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Terpenoid synthase (IPR008949) Polyprenyl synthetase-related (IPR017446)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA735259   AE014296 AAF51668   AI297224   AI404209   AI515178   AW940931   AY051597 AAK93021   AY231696   BF504815   BI163030   BI216532   BI227490   BI232913   BI232916   BI236428   BI236875   BI236982   BI240828   BI364364   BI365950   BI368249   BI368501   BI369310   BI371271   BI373243   BI375692   BI481699   BI483040   BI568404   BI569254   BI569255   BI608647   BI609864   BI638815   BI640758   CL868545   CO299310   FE863486   FE863610   FE863615   FE863873   FE863948   GH743587   GH744929   GH745658   GH745975   GH746023   GH746058   GH746530   GH763916   GH765813   GH766883   GH767027   GH769440
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9VP87
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0037044    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0037044 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of low expression. Peak expression observed within 12-18 embryonic stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0037044 expression level Developmental Stage   Expression Level embryo 00-02hr    1877 embryo 02-04hr    1199 embryo 04-06hr    1870 embryo 06-08hr    1495 embryo 08-10hr    1464 embryo 10-12hr    2275 embryo 12-14hr    4069 embryo 14-16hr    15807 embryo 16-18hr    6026 embryo 18-20hr    2148 embryo 20-22hr    799 embryo 22-24hr    784 larva L1    1180 larva L2    5747 larva L3 12hr old    1447 larva L3 puffstage 1-2    544 larva L3 puffstage 3-6    667 larva L3 puffstage 7-9    543 white prepupae new    380 white prepupae 12hr    817 white prepupae 24hr    737 pupae 2d postWPP    6120 pupae 3d postWPP    3224 pupae 4d postWPP    2145 adult male 01day    774 adult male 05day    911 adult male 30day    925 adult female 01day    1304 adult female 05day    1389 adult female 30day    1488 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (1877) embryo 02-04hr  (1199) embryo 04-06hr  (1870) embryo 06-08hr  (1495) embryo 08-10hr  (1464) embryo 10-12hr  (2275) embryo 12-14hr  (4069) embryo 14-16hr  (15807) embryo 16-18hr  (6026) embryo 18-20hr  (2148) embryo 20-22hr  (799) embryo 22-24hr  (784) larva L1  (1180) larva L2  (5747) larva L3 12hr old  (1447) larva L3 puffstage 1-2  (544) larva L3 puffstage 3-6  (667) larva L3 puffstage 7-9  (543) white prepupae new  (380) white prepupae 12hr  (817) white prepupae 24hr  (737) pupae 2d postWPP  (6120) pupae 3d postWPP  (3224) pupae 4d postWPP  (2145) adult male 01day  (774) adult male 05day  (911) adult male 30day  (925) adult female 01day  (1304) adult female 05day  (1389) adult female 30day  (1488) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (1877) embryo 02-04hr    1199 embryo 04-06hr  (1870) embryo 06-08hr  1495 embryo 08-10hr  1464 embryo 10-12hr  (2275) embryo 12-14hr  (4069) embryo 14-16hr  (15807) embryo 16-18hr  (6026) embryo 18-20hr  (2148) embryo 20-22hr    799 embryo 22-24hr    784 larva L1    1180 larva L2  (5747) larva L3 12hr old  1447 larva L3 puffstage 1-2    544 larva L3 puffstage 3-6    667 larva L3 puffstage 7-9    543 white prepupae new    380 white prepupae 12hr    817 white prepupae 24hr    737 pupae 2d postWPP  (6120) pupae 3d postWPP  (3224) pupae 4d postWPP  (2145) adult male 01day    774 adult male 05day    911 adult male 30day    925 adult female 01day    1304 adult female 05day    1389 adult female 30day  1488 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    1877 embryo 02-04hr    1199 embryo 04-06hr    1870 embryo 06-08hr    1495 embryo 08-10hr    1464 embryo 10-12hr    2275 embryo 12-14hr    4069 embryo 14-16hr  (15807) embryo 16-18hr    6026 embryo 18-20hr    2148 embryo 20-22hr    799 embryo 22-24hr    784 larva L1    1180 larva L2    5747 larva L3 12hr old    1447 larva L3 puffstage 1-2    544 larva L3 puffstage 3-6    667 larva L3 puffstage 7-9    543 white prepupae new    380 white prepupae 12hr    817 white prepupae 24hr    737 pupae 2d postWPP    6120 pupae 3d postWPP    3224 pupae 4d postWPP    2145 adult male 01day    774 adult male 05day    911 adult male 30day    925 adult female 01day    1304 adult female 05day    1389 adult female 30day    1488 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    1877 embryo 02-04hr    1199 embryo 04-06hr    1870 embryo 06-08hr    1495 embryo 08-10hr    1464 embryo 10-12hr    2275 embryo 12-14hr    4069 embryo 14-16hr    15807 embryo 16-18hr    6026 embryo 18-20hr    2148 embryo 20-22hr    799 embryo 22-24hr    784 larva L1    1180 larva L2    5747 larva L3 12hr old    1447 larva L3 puffstage 1-2    544 larva L3 puffstage 3-6    667 larva L3 puffstage 7-9    543 white prepupae new    380 white prepupae 12hr    817 white prepupae 24hr    737 pupae 2d postWPP    6120 pupae 3d postWPP    3224 pupae 4d postWPP    2145 adult male 01day    774 adult male 05day    911 adult male 30day    925 adult female 01day    1304 adult female 05day    1389 adult female 30day    1488 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0037044 expression level Developmental Stage   Expression Level embryo 00-02hr    1877 embryo 02-04hr    1199 embryo 04-06hr    1870 embryo 06-08hr    1495 embryo 08-10hr    1464 embryo 10-12hr    2275 embryo 12-14hr    4069 embryo 14-16hr    15807 embryo 16-18hr    6026 embryo 18-20hr    2148 embryo 20-22hr    799 embryo 22-24hr    784 larva L1    1180 larva L2    5747 larva L3 12hr old    1447 larva L3 puffstage 1-2    544 larva L3 puffstage 3-6    667 larva L3 puffstage 7-9    543 white prepupae new    380 white prepupae 12hr    817 white prepupae 24hr    737 pupae 2d postWPP    6120 pupae 3d postWPP    3224 pupae 4d postWPP    2145 adult male 01day    774 adult male 05day    911 adult male 30day    925 adult female 01day    1304 adult female 05day    1389 adult female 30day    1488 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (1877) embryo 02-04hr  (1199) embryo 04-06hr  (1870) embryo 06-08hr  (1495) embryo 08-10hr  (1464) embryo 10-12hr  (2275) embryo 12-14hr  (4069) embryo 14-16hr  (15807) embryo 16-18hr  (6026) embryo 18-20hr  (2148) embryo 20-22hr  (799) embryo 22-24hr  (784) larva L1  (1180) larva L2  (5747) larva L3 12hr old  (1447) larva L3 puffstage 1-2  (544) larva L3 puffstage 3-6  (667) larva L3 puffstage 7-9  (543) white prepupae new  (380) white prepupae 12hr  (817) white prepupae 24hr  (737) pupae 2d postWPP  (6120) pupae 3d postWPP  (3224) pupae 4d postWPP  (2145) adult male 01day  (774) adult male 05day  (911) adult male 30day  (925) adult female 01day  (1304) adult female 05day  (1389) adult female 30day  (1488) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  1877 embryo 02-04hr    1199 embryo 04-06hr  1870 embryo 06-08hr  1495 embryo 08-10hr  1464 embryo 10-12hr  2275 embryo 12-14hr  (4069) embryo 14-16hr  (15807) embryo 16-18hr  (6026) embryo 18-20hr  2148 embryo 20-22hr    799 embryo 22-24hr    784 larva L1    1180 larva L2  (5747) larva L3 12hr old  1447 larva L3 puffstage 1-2    544 larva L3 puffstage 3-6    667 larva L3 puffstage 7-9    543 white prepupae new    380 white prepupae 12hr    817 white prepupae 24hr    737 pupae 2d postWPP  (6120) pupae 3d postWPP  (3224) pupae 4d postWPP  2145 adult male 01day    774 adult male 05day    911 adult male 30day    925 adult female 01day    1304 adult female 05day    1389 adult female 30day  1488 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    1877 embryo 02-04hr    1199 embryo 04-06hr    1870 embryo 06-08hr    1495 embryo 08-10hr    1464 embryo 10-12hr    2275 embryo 12-14hr    4069 embryo 14-16hr  15807 embryo 16-18hr    6026 embryo 18-20hr    2148 embryo 20-22hr    799 embryo 22-24hr    784 larva L1    1180 larva L2    5747 larva L3 12hr old    1447 larva L3 puffstage 1-2    544 larva L3 puffstage 3-6    667 larva L3 puffstage 7-9    543 white prepupae new    380 white prepupae 12hr    817 white prepupae 24hr    737 pupae 2d postWPP    6120 pupae 3d postWPP    3224 pupae 4d postWPP    2145 adult male 01day    774 adult male 05day    911 adult male 30day    925 adult female 01day    1304 adult female 05day    1389 adult female 30day    1488 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    1877 embryo 02-04hr    1199 embryo 04-06hr    1870 embryo 06-08hr    1495 embryo 08-10hr    1464 embryo 10-12hr    2275 embryo 12-14hr    4069 embryo 14-16hr    15807 embryo 16-18hr    6026 embryo 18-20hr    2148 embryo 20-22hr    799 embryo 22-24hr    784 larva L1    1180 larva L2    5747 larva L3 12hr old    1447 larva L3 puffstage 1-2    544 larva L3 puffstage 3-6    667 larva L3 puffstage 7-9    543 white prepupae new    380 white prepupae 12hr    817 white prepupae 24hr    737 pupae 2d postWPP    6120 pupae 3d postWPP    3224 pupae 4d postWPP    2145 adult male 01day    774 adult male 05day    911 adult male 30day    925 adult female 01day    1304 adult female 05day    1389 adult female 30day    1488 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0037044    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0037044 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: larval/adult central nervous system, adult crop, larval/adult hindgut, larval salivary gland, larval trachea, adult ovary. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0037044 expression level Tissue   Expression Level Larval Central Nervous System    106.75 Larval Midgut    48.8 Larval Hindgut    100.8 Larval Malpighian Tubules    57.2 Larval Fat Body    31.1 Larval Salivary Gland    128.5 Larval Trachea    120.425 Larval Carcass    78.2 Adult Head    77.4 Adult Eye    63.525 Adult Brain    162.7 Adult Thoracic-Abdominal Ganglion    131.6 Adult Crop    320.3 Adult Midgut    54.9 Adult Hindgut    125.1 Adult Malpighian Tubules    96.7 Adult Fat Body    25.9 Adult Salivary Gland    76.4 Adult Heart    39.6 Adult VirginFemale Spermatheca    27.9 Adult InseminatedFemale Spermatheca    32.2 Adult Ovary    147.6 Adult Testis    52 Adult Male Accessory Gland    43.6 Adult Carcass    68 Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    106.75 Larval Midgut    48.8 Larval Hindgut    100.8 Larval Malpighian Tubules    57.2 Larval Fat Body    31.1 Larval Salivary Gland    128.5 Larval Trachea    120.425 Larval Carcass    78.2 Adult Head    77.4 Adult Eye    63.525 Adult Brain    162.7 Adult Thoracic-Abdominal Ganglion    131.6 Adult Crop    320.3 Adult Midgut    54.9 Adult Hindgut    125.1 Adult Malpighian Tubules    96.7 Adult Fat Body    25.9 Adult Salivary Gland    76.4 Adult Heart    39.6 Adult VirginFemale Spermatheca    27.9 Adult InseminatedFemale Spermatheca    32.2 Adult Ovary    147.6 Adult Testis    52 Adult Male Accessory Gland    43.6 Adult Carcass    68 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    106.75 Larval Midgut    48.8 Larval Hindgut    100.8 Larval Malpighian Tubules    57.2 Larval Fat Body    31.1 Larval Salivary Gland    128.5 Larval Trachea    120.425 Larval Carcass    78.2 Adult Head    77.4 Adult Eye    63.525 Adult Brain    162.7 Adult Thoracic-Abdominal Ganglion    131.6 Adult Crop    320.3 Adult Midgut    54.9 Adult Hindgut    125.1 Adult Malpighian Tubules    96.7 Adult Fat Body    25.9 Adult Salivary Gland    76.4 Adult Heart    39.6 Adult VirginFemale Spermatheca    27.9 Adult InseminatedFemale Spermatheca    32.2 Adult Ovary    147.6 Adult Testis    52 Adult Male Accessory Gland    43.6 Adult Carcass    68 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    106.75 Larval Midgut    48.8 Larval Hindgut    100.8 Larval Malpighian Tubules    57.2 Larval Fat Body    31.1 Larval Salivary Gland    128.5 Larval Trachea    120.425 Larval Carcass    78.2 Adult Head    77.4 Adult Eye    63.525 Adult Brain    162.7 Adult Thoracic-Abdominal Ganglion    131.6 Adult Crop    320.3 Adult Midgut    54.9 Adult Hindgut    125.1 Adult Malpighian Tubules    96.7 Adult Fat Body    25.9 Adult Salivary Gland    76.4 Adult Heart    39.6 Adult VirginFemale Spermatheca    27.9 Adult InseminatedFemale Spermatheca    32.2 Adult Ovary    147.6 Adult Testis    52 Adult Male Accessory Gland    43.6 Adult Carcass    68 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0037044 expression level Tissue   Expression Level Larval Central Nervous System    106.75 Larval Midgut    48.8 Larval Hindgut    100.8 Larval Malpighian Tubules    57.2 Larval Fat Body    31.1 Larval Salivary Gland    128.5 Larval Trachea    120.425 Larval Carcass    78.2 Adult Head    77.4 Adult Eye    63.525 Adult Brain    162.7 Adult Thoracic-Abdominal Ganglion    131.6 Adult Crop    320.3 Adult Midgut    54.9 Adult Hindgut    125.1 Adult Malpighian Tubules    96.7 Adult Fat Body    25.9 Adult Salivary Gland    76.4 Adult Heart    39.6 Adult VirginFemale Spermatheca    27.9 Adult InseminatedFemale Spermatheca    32.2 Adult Ovary    147.6 Adult Testis    52 Adult Male Accessory Gland    43.6 Adult Carcass    68 Expression Level Scale  None   Low   Moderate   High  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    106.75 Larval Midgut    48.8 Larval Hindgut    100.8 Larval Malpighian Tubules    57.2 Larval Fat Body    31.1 Larval Salivary Gland    128.5 Larval Trachea    120.425 Larval Carcass    78.2 Adult Head    77.4 Adult Eye    63.525 Adult Brain    162.7 Adult Thoracic-Abdominal Ganglion    131.6 Adult Crop    320.3 Adult Midgut    54.9 Adult Hindgut    125.1 Adult Malpighian Tubules    96.7 Adult Fat Body    25.9 Adult Salivary Gland    76.4 Adult Heart    39.6 Adult VirginFemale Spermatheca    27.9 Adult InseminatedFemale Spermatheca    32.2 Adult Ovary    147.6 Adult Testis    52 Adult Male Accessory Gland    43.6 Adult Carcass    68 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    106.75 Larval Midgut    48.8 Larval Hindgut    100.8 Larval Malpighian Tubules    57.2 Larval Fat Body    31.1 Larval Salivary Gland    128.5 Larval Trachea    120.425 Larval Carcass    78.2 Adult Head    77.4 Adult Eye    63.525 Adult Brain    162.7 Adult Thoracic-Abdominal Ganglion    131.6 Adult Crop    320.3 Adult Midgut    54.9 Adult Hindgut    125.1 Adult Malpighian Tubules    96.7 Adult Fat Body    25.9 Adult Salivary Gland    76.4 Adult Heart    39.6 Adult VirginFemale Spermatheca    27.9 Adult InseminatedFemale Spermatheca    32.2 Adult Ovary    147.6 Adult Testis    52 Adult Male Accessory Gland    43.6 Adult Carcass    68 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    106.75 Larval Midgut    48.8 Larval Hindgut    100.8 Larval Malpighian Tubules    57.2 Larval Fat Body    31.1 Larval Salivary Gland    128.5 Larval Trachea    120.425 Larval Carcass    78.2 Adult Head    77.4 Adult Eye    63.525 Adult Brain    162.7 Adult Thoracic-Abdominal Ganglion    131.6 Adult Crop    320.3 Adult Midgut    54.9 Adult Hindgut    125.1 Adult Malpighian Tubules    96.7 Adult Fat Body    25.9 Adult Salivary Gland    76.4 Adult Heart    39.6 Adult VirginFemale Spermatheca    27.9 Adult InseminatedFemale Spermatheca    32.2 Adult Ovary    147.6 Adult Testis    52 Adult Male Accessory Gland    43.6 Adult Carcass    68 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    77.4   NA  Eye    63.525   NA  Brain    162.7   106.75  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    131.6   NA  Crop    320.3   48.8  Midgut    54.9   100.8  Hindgut    125.1   57.2  Malpighian Tubules    96.7   31.1  Fat Body    25.9   128.5  Salivary Gland    76.4   NA  Heart    39.6   120.425  Trachea    NA   NA  VirginFemale Spermatheca    27.9   NA  InseminatedFemale Spermatheca    32.2   NA  Ovary    147.6   NA  Testis    52   NA  Male Accessory Gland    43.6   78.2  Carcass    68 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_09
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0037044 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG10585-RA FlyExpress - Embryonic expression images (BDGP data) • Show all FlyExpress processed images for CG10585 Stages(s) 1-3 Stages(s) 4-6 Stages(s) 7-8 Stages(s) 9-10 Stages(s) 11-12
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal | pupal stage, with Scer\GAL4pnr-MD237 CG10585GD7029 semi-lethal | pupal stage, with Scer\GAL4pnr-MD237 CG10585GD7029 viable CG10585EY12050 Sterility Allele fertile CG10585EY12050 Other Phenotypes Allele visible, with Scer\GAL4pnr-MD237 CG10585GD7029 Phenotype manifest in Allele mesothoracic tergum, with Scer\GAL4pnr-MD237 CG10585GD7029
Classical Alleles ( 4 )
For All Classical Alleles Show
Allele of CG10585 Class Mutagen Stocks Known lesion CG10585EY00037 P-element activity 1 -- CG10585EY12050 P-element activity 1 -- CG10585f05516 1 -- CG10585GS6087 0 --
Alleles Carried on Transgenic Constructs ( 2 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG10585 Class Mutagen Stocks Known lesion CG10585GD7029 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes CG10585KK102450 in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD7029} NA P{KK102450} NA
Insertions
	Type of insertions Name Expression data insertion of mobile activating element P{EP}skdEP3375 NA P{EP}skdEP3443 NA P{EPgy2}CG10585EY00037 NA P{EPgy2}CG10585EY12050 NA P{GSV3}CG10585GS6087 NA miscellaneous insertions P{SUPor-P}skdKG02102 NA PBac{WH}CG10585f05516 NA
Gene Ontology: Function, Process & Cellular Component ( 1 unique term )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 1 term )
Molecular Function
CV term Evidence References
trans-hexaprenyltranstransferase activity inferred from sequence or structural similarity with Saccharomyces COQ1 (FlyBase, 1992-)
Biological Process ( 0 terms)
Cellular Component ( 0 terms)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG10585 allele Gene References unspecified Nsf2 (Laviolette et al., 2005)
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 65576 DroID - A comprehensive database of gene and protein interactions. • FBgn0037044 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 40323
Orthologs
Genome-wide drosophilid orthologs	Dana\GF24292 Dere\GG16155 Dgri\GH15641 Dmoj\GI12688 Dper\GL24462 Dpse\GA10416 Dsec\GM22336 Dsim\GD14926 Dvir\GJ12673 Dwil\GK25396 Dyak\GE23254
Curated drosophilid orthologs	Dpse\GA10416   Dyak\GE23254
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL001740-PA Aedes aegypti (mosquito) AGAP006015-PA Anopheles gambiae (mosquito) XP_623861.1 Apis mellifera (honey bee) XP_001945782.1 Acyrthosiphon pisum (pea aphid) 115262 Branchiostoma floridae (lancelet) 258960 Branchiostoma floridae (lancelet) BGIBMGA000752-PA Bombyx mori (silk worm) ENSBTAP00000029142 Bos taurus (bovine) ENSCINP00000005299 Ciona intestinalis (sea squirt) CPIJ016311 Culex pipens (mosquito) ENSCPOP00000008342 Cavia porcellus (guinea pig) 194798 Capitella spl (polychaete worm) 194691 Daphnia pulex (daphnia) ENSDARP00000005394 Danio rerio (zebra fish) ENSGACP00000016878 Gymnopilus aculeatus (mushroom) ENSGALP00000024670 Gallus gallus (chicken) 111519 Hypsipyla robusta (cedar shoot borer) ENSP00000358033 Homo sapiens (human) ISCW013145-PA Ixodes scapularis (deer tick) 209876 Lottia gigantea (owl limpet) ENSMODP00000022466 Monodelphis domestica (gray opossum) ENSMMUP00000003035 Macaca mulatta (rhesus monkey) ENSMUSP00000093393 Mus musculus (house mouse) 168669 Nematostella vectensis (starlet anemone) XP_001605067.1 Nasonia vitripennis (wasp) ENSOANP00000001214 Ornithorynchus anatinus (platypus) PHUM000432-PA Pediculus humanus (human body louse) ENSPPYP00000018906 Pongo pygmaeus (orangutan) ENSPTRP00000031540 Pan troglodytes (chimpanzee) ENSRNOP00000049086 Rattus norvegicus (norway rat) XP_785706.2 Strongylocentrotus purpuratus (purple sea urchin) 56502 Trichoplax adhaerens (metazoa) XP_970126.1 Tribolium castaneum (red flour beetle) ENSTNIP00000011768 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000027934 Takifugu rubripes (pufferfish Takifugu) ENSXETP00000041737 Xenopus tropicalis (frog) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • NV11656 LH22338 LH12284 LH14787 ISCW013145 FBgn0237056 FBgn0068503 FBgn0227355 FBgn0199910 FBgn0186598 FBgn0177206 JGI_V11_99962 JGI_V11_194691 FBgn0070473 FBgn0162051 FBgn0135445 FBgn0123112 FBgn0108390 FBgn0101286 CPIJ016311 BGIBMGA012681 BGIBMGA012682 BGIBMGA009744 BGIBMGA000823 BGIBMGA000752 ACYPI008833 ACYPI005073 GB13311 AGAP006015 AAEL001740 PHUM287700 GLEAN_14811 GLEAN_14812
Stocks & Reagents
Stocks Listed in FlyBase ( 5 )
Bloomington	14801 y1 w67c23; P{EPgy2}CG10585EY00037 20725 y1 w67c23; P{EPgy2}CG10585EY12050
Harvard	- PBac{WH}CG10585f05516
VDRC	v31272 w1118; P{GD7029}v31272 v31273 w1118; P{GD7029}v31273
Genomic Clones ( 1 )
	BACR03J02 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 49 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	GH23839
Other clones	yak-em_CG10585
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT06845 LD02392 LD46891 LP11483 RE02325 RE23702 RE24548 RE29054 RE29066 RE32481 RE33004 RE33123 RE37762 RE49457 RE51357 RE54182 RE54481 RE55449 RE58133 RE60489 RE63555 RE64292 RE65875 RH13243 RH14706 RH39844 SD21206 SD23752
Other clones	EK175054 RH01383 RM07401 RM07501 RM07601 RM08001 RM08101 RP001004261 RP001008571 RP001013913 RP001015515 RP001016276 RP001022790 RP001023949 RP001032720 RP001039549 RP001039809 RP001042575 RP001044507
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0037044 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 40323
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_141020 RefSeq (Proteins) • NP_649277 DDBJ / EMBL / GenBank • AAF51668 AAK93021 AI404209 AW940931 AY051597 CL868545 Entrez Gene - A searchable database of RefSeq genes. • 40323 UniProtKB/TrEMBL • Q9VP87
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Terpenoid synthase (IPR008949) Polyprenyl synthetase-related (IPR017446)
Linkouts
	BioGRID - A database of protein and genetic interactions • 65576 DroID - A comprehensive database of gene and protein interactions. • FBgn0037044 DRSC - Results from RNAi screens. • FBgn0037044 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0037044 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG10585-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0037044 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 40323 InParanoid A subset of ortholog calls from InParanoid. • AAEL001740-PA Aedes aegypti (mosquito) AGAP006015-PA Anopheles gambiae (mosquito) XP_623861.1 Apis mellifera (honey bee) XP_001945782.1 Acyrthosiphon pisum (pea aphid) 115262 Branchiostoma floridae (lancelet) 258960 Branchiostoma floridae (lancelet) BGIBMGA000752-PA Bombyx mori (silk worm) ENSBTAP00000029142 Bos taurus (bovine) ENSCINP00000005299 Ciona intestinalis (sea squirt) CPIJ016311 Culex pipens (mosquito) ENSCPOP00000008342 Cavia porcellus (guinea pig) 194798 Capitella spl (polychaete worm) 194691 Daphnia pulex (daphnia) ENSDARP00000005394 Danio rerio (zebra fish) ENSGACP00000016878 Gymnopilus aculeatus (mushroom) ENSGALP00000024670 Gallus gallus (chicken) 111519 Hypsipyla robusta (cedar shoot borer) ENSP00000358033 Homo sapiens (human) ISCW013145-PA Ixodes scapularis (deer tick) 209876 Lottia gigantea (owl limpet) ENSMODP00000022466 Monodelphis domestica (gray opossum) ENSMMUP00000003035 Macaca mulatta (rhesus monkey) ENSMUSP00000093393 Mus musculus (house mouse) 168669 Nematostella vectensis (starlet anemone) XP_001605067.1 Nasonia vitripennis (wasp) ENSOANP00000001214 Ornithorynchus anatinus (platypus) PHUM000432-PA Pediculus humanus (human body louse) ENSPPYP00000018906 Pongo pygmaeus (orangutan) ENSPTRP00000031540 Pan troglodytes (chimpanzee) ENSRNOP00000049086 Rattus norvegicus (norway rat) XP_785706.2 Strongylocentrotus purpuratus (purple sea urchin) 56502 Trichoplax adhaerens (metazoa) XP_970126.1 Tribolium castaneum (red flour beetle) ENSTNIP00000011768 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000027934 Takifugu rubripes (pufferfish Takifugu) ENSXETP00000041737 Xenopus tropicalis (frog) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 40323 modMine - Data generated by the modENCODE project. • FBgn0037044 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • NV11656 LH22338 LH12284 LH14787 ISCW013145 FBgn0237056 FBgn0068503 FBgn0227355 FBgn0199910 FBgn0186598 FBgn0177206 JGI_V11_99962 JGI_V11_194691 FBgn0070473 FBgn0162051 FBgn0135445 FBgn0123112 FBgn0108390 FBgn0101286 CPIJ016311 BGIBMGA012681 BGIBMGA012682 BGIBMGA009744 BGIBMGA000823 BGIBMGA000752 ACYPI008833 ACYPI005073 GB13311 AGAP006015 AAEL001740 PHUM287700 GLEAN_14811 GLEAN_14812
Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	CG10585 (Laviolette et al., 2005, Haussmann et al., 2008, Keleman et al., 2009.8.5)
Name Synonym
Secondary FlyBase IDs
References ( 14 )
Research paper	Blanco et al., 2010, BMC Dev. Biol. 10: 94 Gene expression following induction of regeneration in Drosophila wing imaginal discs. Expression profile of regenerating wing discs. [FBrf0211812] Haussmann et al., 2008, Genome Biol. 9(4): R73 Erect wing regulates synaptic growth in Drosophila by integration of multiple signaling pathways. [FBrf0209726] Laviolette et al., 2005, Genetics 170(2): 779--792 A genetic screen for suppressors of Drosophila NSF2 neuromuscular junction overgrowth. [FBrf0187645]
Supplementary material	The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518] Giot et al., 2003, Science 302(5651): Tables S1 to S7. [FBrf0166452]
Personal communication to FlyBase	Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327]
FlyBase analysis	FlyBase Curators, 2008, Insertion identifiers and alleles based on genomic location of insertions with respect to gene annotations. Insertion identifiers and alleles based on genomic location of insertions with respect to gene annotations. [FBrf0202955] FlyBase, 1992-, FlyBase curation FlyBase curation. [FBrf0105495]
Computer file	Gene Disruption Project members, 2001-, [title not yet available] [title not yet available] [FBrf0132177] BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. Berkeley Drosophila Genome Project. [FBrf0125078]
Automatic genome annotation	FamiliarityBreedsContempt, 1999.11, [Annotations performed at the Celera Jamboreee.] [Annotations performed at the Celera Jamboreee.] [FBrf0126705]