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Gene Dmel\Cpr78Cb

General Information
Symbol	Dmel\Cpr78Cb	Species	D. melanogaster
Name	Cuticular protein 78Cb	Annotation symbol	CG7663
Feature type	protein_coding_gene	FlyBase ID	FBgn0037068
Gene Model Status	Current	Stock availability	2 publicly available
Genomic Location
Chromosome (arm)	3L	Recombination map
Cytogenetic map	78C6-78C6	Sequence location	3L:21,288,498..21,289,798 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene Cuticular protein 78Cb is referred to in FlyBase by the symbol Dmel\Cpr78Cb (CG7663, FBgn0037068). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: structural constituent of chitin-based cuticle. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Insect cuticle protein. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of extremely low expression. Peak expression observed within 18-24 hour embryonic stages. Summary of FlyAtlas Anatomical Expression Data: No expression detected in any larval or adult organs/tissues. Comments on Affy2 ProbeSet: ProbeSet 1633426_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of Cpr78Cb. Gene sequence location is 3L:21288498..21289798.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2011_10
FB2012_01	Sequence features BKN29869 HFA11847
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 78C6-78C6   Limits computationally determined from genome sequence between P{lacW}l(3)j1B10j1B10 and P{lacW}l(3)j2C4j2C4
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\Cpr78Cb for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.43
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) Cpr78Cb-RA FBtr0078337  NM_141042   1218   140
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein Cpr78Cb-PA   FBpp0077993   15.9   140   6.97     NP_649299   AAF51701
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Insect cuticle protein (IPR000618)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE014296 AAF51701   AI467772   AY075480   BI241324   BI371593   CO179418   EC194956   EC195205   EC241750   GH750203   GH753665   GH754911   GH757087   GH760277   GH772151   GH775888   GH789254   GH791493   GH797304   GH801691   GH807041   GH812667   GH813836   GH819392   GH819952   GH822311   GH822756   GH823379   GH828495   GH832225   GH834972   GH836981   GH841202   GH842037   GH843673   GH844329   GH850582   GH850761   GH854849   GH854969   GH857105   GH857160   GH866035   GH875342   GH889652   GH890202   GH891420   GH897078   GH898489   GH902388   GH904308   GH905668   GH906553   GH907034   GH910141   GH915308   GH921123   GH926058   GH930883   GH934146   GH935947   GH939622   GH940626
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9VP55
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0037068    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0037068 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of extremely low expression. Peak expression observed within 18-24 hour embryonic stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0037068 expression level Developmental Stage   Expression Level embryo 00-02hr    11 embryo 02-04hr    41 embryo 04-06hr    110 embryo 06-08hr    56 embryo 08-10hr    135 embryo 10-12hr    422 embryo 12-14hr    393 embryo 14-16hr    282 embryo 16-18hr    3110 embryo 18-20hr    8274 embryo 20-22hr    3558 embryo 22-24hr    3839 larva L1    446 larva L2    595 larva L3 12hr old    1174 larva L3 puffstage 1-2    30 larva L3 puffstage 3-6    15 larva L3 puffstage 7-9    23 white prepupae new    92 white prepupae 12hr    89 white prepupae 24hr    16 pupae 2d postWPP    97 pupae 3d postWPP    673 pupae 4d postWPP    12 adult male 01day    3 adult male 05day    4 adult male 30day    5 adult female 01day    4 adult female 05day    5 adult female 30day    1 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr    11 embryo 02-04hr    41 embryo 04-06hr  (110) embryo 06-08hr    56 embryo 08-10hr  (135) embryo 10-12hr  (422) embryo 12-14hr  (393) embryo 14-16hr  (282) embryo 16-18hr  (3110) embryo 18-20hr  (8274) embryo 20-22hr  (3558) embryo 22-24hr  (3839) larva L1  (446) larva L2  (595) larva L3 12hr old  (1174) larva L3 puffstage 1-2    30 larva L3 puffstage 3-6    15 larva L3 puffstage 7-9    23 white prepupae new    92 white prepupae 12hr    89 white prepupae 24hr    16 pupae 2d postWPP    97 pupae 3d postWPP  (673) pupae 4d postWPP    12 adult male 01day    3 adult male 05day    4 adult male 30day    5 adult female 01day    4 adult female 05day    5 adult female 30day    1 Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    11 embryo 02-04hr    41 embryo 04-06hr    110 embryo 06-08hr    56 embryo 08-10hr    135 embryo 10-12hr    422 embryo 12-14hr    393 embryo 14-16hr    282 embryo 16-18hr  (3110) embryo 18-20hr  (8274) embryo 20-22hr  (3558) embryo 22-24hr  (3839) larva L1    446 larva L2    595 larva L3 12hr old    1174 larva L3 puffstage 1-2    30 larva L3 puffstage 3-6    15 larva L3 puffstage 7-9    23 white prepupae new    92 white prepupae 12hr    89 white prepupae 24hr    16 pupae 2d postWPP    97 pupae 3d postWPP    673 pupae 4d postWPP    12 adult male 01day    3 adult male 05day    4 adult male 30day    5 adult female 01day    4 adult female 05day    5 adult female 30day    1 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    11 embryo 02-04hr    41 embryo 04-06hr    110 embryo 06-08hr    56 embryo 08-10hr    135 embryo 10-12hr    422 embryo 12-14hr    393 embryo 14-16hr    282 embryo 16-18hr    3110 embryo 18-20hr    8274 embryo 20-22hr    3558 embryo 22-24hr    3839 larva L1    446 larva L2    595 larva L3 12hr old    1174 larva L3 puffstage 1-2    30 larva L3 puffstage 3-6    15 larva L3 puffstage 7-9    23 white prepupae new    92 white prepupae 12hr    89 white prepupae 24hr    16 pupae 2d postWPP    97 pupae 3d postWPP    673 pupae 4d postWPP    12 adult male 01day    3 adult male 05day    4 adult male 30day    5 adult female 01day    4 adult female 05day    5 adult female 30day    1 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    11 embryo 02-04hr    41 embryo 04-06hr    110 embryo 06-08hr    56 embryo 08-10hr    135 embryo 10-12hr    422 embryo 12-14hr    393 embryo 14-16hr    282 embryo 16-18hr    3110 embryo 18-20hr    8274 embryo 20-22hr    3558 embryo 22-24hr    3839 larva L1    446 larva L2    595 larva L3 12hr old    1174 larva L3 puffstage 1-2    30 larva L3 puffstage 3-6    15 larva L3 puffstage 7-9    23 white prepupae new    92 white prepupae 12hr    89 white prepupae 24hr    16 pupae 2d postWPP    97 pupae 3d postWPP    673 pupae 4d postWPP    12 adult male 01day    3 adult male 05day    4 adult male 30day    5 adult female 01day    4 adult female 05day    5 adult female 30day    1 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0037068 expression level Developmental Stage   Expression Level embryo 00-02hr    11 embryo 02-04hr    41 embryo 04-06hr    110 embryo 06-08hr    56 embryo 08-10hr    135 embryo 10-12hr    422 embryo 12-14hr    393 embryo 14-16hr    282 embryo 16-18hr    3110 embryo 18-20hr    8274 embryo 20-22hr    3558 embryo 22-24hr    3839 larva L1    446 larva L2    595 larva L3 12hr old    1174 larva L3 puffstage 1-2    30 larva L3 puffstage 3-6    15 larva L3 puffstage 7-9    23 white prepupae new    92 white prepupae 12hr    89 white prepupae 24hr    16 pupae 2d postWPP    97 pupae 3d postWPP    673 pupae 4d postWPP    12 adult male 01day    3 adult male 05day    4 adult male 30day    5 adult female 01day    4 adult female 05day    5 adult female 30day    1 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr    11 embryo 02-04hr    41 embryo 04-06hr  110 embryo 06-08hr    56 embryo 08-10hr  135 embryo 10-12hr  (422) embryo 12-14hr  (393) embryo 14-16hr  (282) embryo 16-18hr  (3110) embryo 18-20hr  (8274) embryo 20-22hr  (3558) embryo 22-24hr  (3839) larva L1  (446) larva L2  (595) larva L3 12hr old  (1174) larva L3 puffstage 1-2    30 larva L3 puffstage 3-6    15 larva L3 puffstage 7-9    23 white prepupae new    92 white prepupae 12hr    89 white prepupae 24hr    16 pupae 2d postWPP    97 pupae 3d postWPP  (673) pupae 4d postWPP    12 adult male 01day    3 adult male 05day    4 adult male 30day    5 adult female 01day    4 adult female 05day    5 adult female 30day    1 Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    11 embryo 02-04hr    41 embryo 04-06hr    110 embryo 06-08hr    56 embryo 08-10hr    135 embryo 10-12hr    422 embryo 12-14hr    393 embryo 14-16hr    282 embryo 16-18hr  (3110) embryo 18-20hr  (8274) embryo 20-22hr  (3558) embryo 22-24hr  (3839) larva L1    446 larva L2    595 larva L3 12hr old    1174 larva L3 puffstage 1-2    30 larva L3 puffstage 3-6    15 larva L3 puffstage 7-9    23 white prepupae new    92 white prepupae 12hr    89 white prepupae 24hr    16 pupae 2d postWPP    97 pupae 3d postWPP    673 pupae 4d postWPP    12 adult male 01day    3 adult male 05day    4 adult male 30day    5 adult female 01day    4 adult female 05day    5 adult female 30day    1 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    11 embryo 02-04hr    41 embryo 04-06hr    110 embryo 06-08hr    56 embryo 08-10hr    135 embryo 10-12hr    422 embryo 12-14hr    393 embryo 14-16hr    282 embryo 16-18hr    3110 embryo 18-20hr    8274 embryo 20-22hr    3558 embryo 22-24hr    3839 larva L1    446 larva L2    595 larva L3 12hr old    1174 larva L3 puffstage 1-2    30 larva L3 puffstage 3-6    15 larva L3 puffstage 7-9    23 white prepupae new    92 white prepupae 12hr    89 white prepupae 24hr    16 pupae 2d postWPP    97 pupae 3d postWPP    673 pupae 4d postWPP    12 adult male 01day    3 adult male 05day    4 adult male 30day    5 adult female 01day    4 adult female 05day    5 adult female 30day    1 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    11 embryo 02-04hr    41 embryo 04-06hr    110 embryo 06-08hr    56 embryo 08-10hr    135 embryo 10-12hr    422 embryo 12-14hr    393 embryo 14-16hr    282 embryo 16-18hr    3110 embryo 18-20hr    8274 embryo 20-22hr    3558 embryo 22-24hr    3839 larva L1    446 larva L2    595 larva L3 12hr old    1174 larva L3 puffstage 1-2    30 larva L3 puffstage 3-6    15 larva L3 puffstage 7-9    23 white prepupae new    92 white prepupae 12hr    89 white prepupae 24hr    16 pupae 2d postWPP    97 pupae 3d postWPP    673 pupae 4d postWPP    12 adult male 01day    3 adult male 05day    4 adult male 30day    5 adult female 01day    4 adult female 05day    5 adult female 30day    1 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0037068    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0037068 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: No expression detected in any larval or adult organs/tissues. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0037068 expression level Tissue   Expression Level Larval Central Nervous System    3.575 Larval Midgut    3.9 Larval Hindgut    3.4 Larval Malpighian Tubules    2.5 Larval Fat Body    3.2 Larval Salivary Gland    4.6 Larval Trachea    5.175 Larval Carcass no informative data Adult Head    4 Adult Eye    3.775 Adult Brain    3.2 Adult Thoracic-Abdominal Ganglion    2.6 Adult Crop    4.8 Adult Midgut    3.8 Adult Hindgut    3.2 Adult Malpighian Tubules    3 Adult Fat Body    6.9 Adult Salivary Gland no informative data Adult Heart    1.3 Adult VirginFemale Spermatheca    5.5 Adult InseminatedFemale Spermatheca    2.3 Adult Ovary    1.6 Adult Testis    1.2 Adult Male Accessory Gland no informative data Adult Carcass    8.4 Expression Level Scale  None   Low  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    3.575 Larval Midgut    3.9 Larval Hindgut    3.4 Larval Malpighian Tubules    2.5 Larval Fat Body    3.2 Larval Salivary Gland    4.6 Larval Trachea    5.175 Larval Carcass no informative data Adult Head    4 Adult Eye    3.775 Adult Brain    3.2 Adult Thoracic-Abdominal Ganglion    2.6 Adult Crop    4.8 Adult Midgut    3.8 Adult Hindgut    3.2 Adult Malpighian Tubules    3 Adult Fat Body    6.9 Adult Salivary Gland no informative data Adult Heart    1.3 Adult VirginFemale Spermatheca    5.5 Adult InseminatedFemale Spermatheca    2.3 Adult Ovary    1.6 Adult Testis    1.2 Adult Male Accessory Gland no informative data Adult Carcass    8.4 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    3.575 Larval Midgut    3.9 Larval Hindgut    3.4 Larval Malpighian Tubules    2.5 Larval Fat Body    3.2 Larval Salivary Gland    4.6 Larval Trachea    5.175 Larval Carcass no informative data Adult Head    4 Adult Eye    3.775 Adult Brain    3.2 Adult Thoracic-Abdominal Ganglion    2.6 Adult Crop    4.8 Adult Midgut    3.8 Adult Hindgut    3.2 Adult Malpighian Tubules    3 Adult Fat Body    6.9 Adult Salivary Gland no informative data Adult Heart    1.3 Adult VirginFemale Spermatheca    5.5 Adult InseminatedFemale Spermatheca    2.3 Adult Ovary    1.6 Adult Testis    1.2 Adult Male Accessory Gland no informative data Adult Carcass    8.4 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    3.575 Larval Midgut    3.9 Larval Hindgut    3.4 Larval Malpighian Tubules    2.5 Larval Fat Body    3.2 Larval Salivary Gland    4.6 Larval Trachea    5.175 Larval Carcass no informative data Adult Head    4 Adult Eye    3.775 Adult Brain    3.2 Adult Thoracic-Abdominal Ganglion    2.6 Adult Crop    4.8 Adult Midgut    3.8 Adult Hindgut    3.2 Adult Malpighian Tubules    3 Adult Fat Body    6.9 Adult Salivary Gland no informative data Adult Heart    1.3 Adult VirginFemale Spermatheca    5.5 Adult InseminatedFemale Spermatheca    2.3 Adult Ovary    1.6 Adult Testis    1.2 Adult Male Accessory Gland no informative data Adult Carcass    8.4 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0037068 expression level Tissue   Expression Level Larval Central Nervous System    3.575 Larval Midgut    3.9 Larval Hindgut    3.4 Larval Malpighian Tubules    2.5 Larval Fat Body    3.2 Larval Salivary Gland    4.6 Larval Trachea    5.175 Larval Carcass no informative data Adult Head    4 Adult Eye    3.775 Adult Brain    3.2 Adult Thoracic-Abdominal Ganglion    2.6 Adult Crop    4.8 Adult Midgut    3.8 Adult Hindgut    3.2 Adult Malpighian Tubules    3 Adult Fat Body    6.9 Adult Salivary Gland no informative data Adult Heart    1.3 Adult VirginFemale Spermatheca    5.5 Adult InseminatedFemale Spermatheca    2.3 Adult Ovary    1.6 Adult Testis    1.2 Adult Male Accessory Gland no informative data Adult Carcass    8.4 Expression Level Scale  None   Low  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    3.575 Larval Midgut    3.9 Larval Hindgut    3.4 Larval Malpighian Tubules    2.5 Larval Fat Body    3.2 Larval Salivary Gland    4.6 Larval Trachea    5.175 Larval Carcass no informative data Adult Head    4 Adult Eye    3.775 Adult Brain    3.2 Adult Thoracic-Abdominal Ganglion    2.6 Adult Crop    4.8 Adult Midgut    3.8 Adult Hindgut    3.2 Adult Malpighian Tubules    3 Adult Fat Body    6.9 Adult Salivary Gland no informative data Adult Heart    1.3 Adult VirginFemale Spermatheca    5.5 Adult InseminatedFemale Spermatheca    2.3 Adult Ovary    1.6 Adult Testis    1.2 Adult Male Accessory Gland no informative data Adult Carcass    8.4 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    3.575 Larval Midgut    3.9 Larval Hindgut    3.4 Larval Malpighian Tubules    2.5 Larval Fat Body    3.2 Larval Salivary Gland    4.6 Larval Trachea    5.175 Larval Carcass no informative data Adult Head    4 Adult Eye    3.775 Adult Brain    3.2 Adult Thoracic-Abdominal Ganglion    2.6 Adult Crop    4.8 Adult Midgut    3.8 Adult Hindgut    3.2 Adult Malpighian Tubules    3 Adult Fat Body    6.9 Adult Salivary Gland no informative data Adult Heart    1.3 Adult VirginFemale Spermatheca    5.5 Adult InseminatedFemale Spermatheca    2.3 Adult Ovary    1.6 Adult Testis    1.2 Adult Male Accessory Gland no informative data Adult Carcass    8.4 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    3.575 Larval Midgut    3.9 Larval Hindgut    3.4 Larval Malpighian Tubules    2.5 Larval Fat Body    3.2 Larval Salivary Gland    4.6 Larval Trachea    5.175 Larval Carcass no informative data Adult Head    4 Adult Eye    3.775 Adult Brain    3.2 Adult Thoracic-Abdominal Ganglion    2.6 Adult Crop    4.8 Adult Midgut    3.8 Adult Hindgut    3.2 Adult Malpighian Tubules    3 Adult Fat Body    6.9 Adult Salivary Gland no informative data Adult Heart    1.3 Adult VirginFemale Spermatheca    5.5 Adult InseminatedFemale Spermatheca    2.3 Adult Ovary    1.6 Adult Testis    1.2 Adult Male Accessory Gland no informative data Adult Carcass    8.4 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass no informative data Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland no informative data Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland no informative data Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    4   NA  Eye    3.775   NA  Brain    3.2   3.575  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    2.6   NA  Crop    4.8   3.9  Midgut    3.8   3.4  Hindgut    3.2   2.5  Malpighian Tubules    3   3.2  Fat Body    6.9   4.6  Salivary Gland    no informative data   NA  Heart    1.3   5.175  Trachea    NA   NA  VirginFemale Spermatheca    5.5   NA  InseminatedFemale Spermatheca    2.3   NA  Ovary    1.6   NA  Testis    1.2   NA  Male Accessory Gland    no informative data   no informative data  Carcass    8.4 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_12
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0037068 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG7663-RA FlyExpress - Embryonic expression images (BDGP data) • Show all FlyExpress processed images for Cpr78Cb Stages(s) 4-6 Stages(s) 7-8 Stages(s) 11-12 Stages(s) 13-16
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable, with Scer\GAL4pnr-MD237 Cpr78CbGD5545 Phenotype manifest in Allele
Classical Alleles ( 0 )
For All Classical Alleles Show
Allele of Cpr78Cb Class Mutagen Stocks Known lesion
Alleles Carried on Transgenic Constructs ( 2 )
For All Alleles Carried on Transgenic Constructs Show
Allele of Cpr78Cb Class Mutagen Stocks Known lesion Cpr78CbGD5545 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes Cpr78CbKK109869 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD5545} NA P{KK109869} NA
Insertions
	Type of insertions Name Expression data
Gene Ontology: Function, Process & Cellular Component ( 1 unique term )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 1 term )
Molecular Function
CV term Evidence References
structural constituent of chitin-based cuticle inferred from sequence or structural similarity with InterPro:IPR000618 (Willis, 2007.1.3) inferred from sequence or structural similarity with Pfam:PF00379 (Willis, 2007.1.3)
Biological Process ( 0 terms)
Cellular Component ( 0 terms)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions Cpr78Cb allele Gene References
External Data
Linkouts	DroID - A comprehensive database of gene and protein interactions. • FBgn0037068
Orthologs
Genome-wide drosophilid orthologs	Dana\GF10273 Dere\GG16170 Dgri\GH14974 Dper\GL24677 Dpse\GA23946 Dsec\GM22353 Dsim\GD14947 Dvir\GJ13884 Dwil\GK20465 Dyak\GE23260
Curated drosophilid orthologs	Dpse\GA20510
Linkouts	OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • FBgn0240457 FBgn0237072 FBgn0222462 FBgn0201103 FBgn0186619 FBgn0177223 FBgn0245345 FBgn0162265 FBgn0122449 FBgn0108405 FBgn0087314
Stocks & Reagents
Stocks Listed in FlyBase ( 2 )
VDRC	v107767 P{KK109869}VIE-260B v31058 w1118; P{GD5545}v31058
Genomic Clones ( 1 )
	BACR02C22 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 60 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	RE38359
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	RE58518
Other clones	CK01.27C.D3 CK01.42C.G6 CK01.75D.B4 EK059338 RP003036347 RP003055119 RP003061323 RP003068134 RP003068316 RP003068588 RP003090479 RP003097552 RP003099742 RP003102345 RP003115266 RP003125097 RP003128449 RP003146136 RP003166395 RP003173985 RP003177808 RP003204036 RP003212014 RP003216097 RP003229460 RP003230552 RP003241542 RP003252245 RP003263533 RP003265012 RP003266468 RP003313701 RP003328375 RP003331405 RP003337218 RP003357219 RP003384875 RP003390134 RP003451546 RP003459861 RP003462566 RP003470791 RP003472101 RP003504991 RP003518798 RP003543658 RP003545907 RP003552379 RP003557398 RP003577467 RP003584728 RP003586547 RP003587304 RP003592512 RP003625106 RP003653567 RP003661986 RP003672494
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0037068 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 40353
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of	Source for identity of: Cpr78Cb CG7663 (Willis, 2007.1.3)
Source for database merge of	Source for merge of: CG7663 anon-EST:ParkEST240 (Bayraktaroglu, 2000.11.2) Source for merge of: CG7663 BcDNA:RE38359 (FlyBase, 1996-)
Additional comments	Source for merge of CG7663 BcDNA:RE38359 was a shared cDNA (date:030728). (FlyBase, 1996-)
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_141042 RefSeq (Proteins) • NP_649299 DDBJ / EMBL / GenBank • AAF51701 AI467772 AY075480 BI241324 Entrez Gene - A searchable database of RefSeq genes. • 40353 UniProtKB/TrEMBL • Q9VP55
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Insect cuticle protein (IPR000618)
Linkouts
	DroID - A comprehensive database of gene and protein interactions. • FBgn0037068 DRSC - Results from RNAi screens. • FBgn0037068 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0037068 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG7663-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0037068 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 40353 modMine - Data generated by the modENCODE project. • FBgn0037068 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • FBgn0240457 FBgn0237072 FBgn0222462 FBgn0201103 FBgn0186619 FBgn0177223 FBgn0245345 FBgn0162265 FBgn0122449 FBgn0108405 FBgn0087314
Synonyms & Secondary IDs ( 6 )
Reported As
Symbol Synonym	anon-EST:ParkEST240   BcDNA:RE38359   CG7663 (Shah et al., 2008, Keleman et al., 2009.8.5, Blanco et al., 2008) Cpr78Cb (Willis, 2007.1.3, Karouzou et al., 2007, Karouzou et al., 2007) DmelCpr78Cb (Karouzou et al., 2007)
Name Synonym	CG7663   Cuticular protein 78Cb
Secondary FlyBase IDs
	FBgn0026288 FBgn0061402
References ( 18 )
Research paper	Blanco et al., 2008, Genome Biol. 9(9): R134 Conserved chromosomal clustering of genes governed by chromatin regulators in Drosophila. [FBrf0207036] Shah et al., 2008, Gene 407(1-2): 199--215 Enhanced function annotations for Drosophila serine proteases: A case study for systematic annotation of multi-member gene families. [FBrf0202030] Kearney et al., 2004, Dev. Biol. 275(2): 473--492 Gene expression profiling of the developing Drosophila CNS midline cells. [FBrf0180108]
Supplementary material	The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518] Karouzou et al., 2007, Insect Biochem. Mol. Biol. 37(8): Table S1. [FBrf0200185] Karouzou et al., 2007, Insect Biochem. Mol. Biol. 37(8): Tables S2-S5. [FBrf0200186]
Review	Karouzou et al., 2007, Insect Biochem. Mol. Biol. 37(8): 754--760 Drosophila cuticular proteins with the R&R Consensus: annotation and classification with a new tool for discriminating RR-1 and RR-2 sequences. [FBrf0200175]
Personal communication to FlyBase	Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] Willis, 2007.1.3, Drosophila genes that have the R&R consensus. Drosophila genes that have the R&R consensus. [FBrf0199281] FlyBase Curators et al., 2004-, Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. [FBrf0174215] Bayraktaroglu, 2000.11.2, Current list of possibly CG-able known genes. Current list of possibly CG-able known genes. [FBrf0131225]
FlyBase analysis	FlyBase, 1996-, FlyBase inference based on genome sequence analysis. FlyBase inference based on genome sequence analysis. [FBrf0104946] FlyBase, 1992-, FlyBase curation FlyBase curation. [FBrf0105495]
Computer file	BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. Berkeley Drosophila Genome Project. [FBrf0125078]
Curated genome annotation	Ashburner, 1999.11, [Annotations performed at the Celera Jamboreee.] [Annotations performed at the Celera Jamboreee.] [FBrf0126651]
Automatic genome annotation	FamiliarityBreedsContempt, 1999.11, [Annotations performed at the Celera Jamboreee.] [Annotations performed at the Celera Jamboreee.] [FBrf0126705]