• Home
• Tools
  • Tools Overview
  • Query Tools

    
    • QuickSearch
    • QueryBuilder
    • TermLink
    • CytoSearch
    • RNA-Seq Search
    • Interactions Browser
    • ImageBrowse
    • Find A Person
    • Google™ FlyBase
  • Genomic/Map Tools

    
    • BLAST
    • GBrowse
    • GBrowse 2 Beta
    • CytoSearch
    • Feature Mapper
    • Aberrations Maps
    • Chromosome Maps
    • Coordinates Converter
  • Retrieve/Convert

    
    • Batch Download
    • Coordinates Converter
    • ID Converter
  • Data Submission

    
    • Fast-Track Your Paper
    • Submit Personal Comm
    • Add A New Person
    • Update Person Info
  • People

    
    • Find A Person
    • Add A New Person
    • Update Person Info
• Files
  • Files Overview
  • Current release
  • Archived releases
  • Map Conversion
  • FTP site:
  • Releases (FTP)
  • Genomes (FTP)
• Species
  • Phylogeny
  • Sequenced Species
  • Synteny Table
  • Color Illustrations
  • Abbreviations
• Documents
  • About FlyBase
  • Reference Manual:
  • Sections
  • Contents
  • Nomenclature
  • Release Notes
• Resources
  • All Resources
  • Model Organisms
  • Stock Collections
  • Vectors & Constructs
  • Other links:
  • BDGP
  • DGRC
  • DIS by issue
  • FlyExpress
  • Interactive Fly
  • modENCODE
  • Textpresso for Fly
• News
  • News
  • FlyBase Forum
  • FlyBase Positions
  • Meetings
  • Courses
  • Fly Board
  • White papers
  • Funding
  • bionet.dros
• Help
  • Google™ FlyBase
  • Site Map
  • FAQs
  • FlyBase Guides
  • Video Tutorials
  • Report help
  • New to Flies
  • Pers. comm.
  • Author guidelines
  • Contact FlyBase
• Archives
  • Prior Release
  • Other Archives
  • Coordinate Converter

Gene Dmel\Cpr78Cc

General Information
Symbol	Dmel\Cpr78Cc	Species	D. melanogaster
Name	Cuticular protein 78Cc	Annotation symbol	CG7658
Feature type	protein_coding_gene	FlyBase ID	FBgn0037069
Gene Model Status	Current	Stock availability	3 publicly available
Genomic Location
Chromosome (arm)	3L	Recombination map
Cytogenetic map	78C6-78C6	Sequence location	3L:21,293,680..21,294,271 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene Cuticular protein 78Cc is referred to in FlyBase by the symbol Dmel\Cpr78Cc (CG7658, FBgn0037069). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: structural constituent of chitin-based cuticle; structural constituent of chitin-based larval cuticle. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Insect cuticle protein. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of extremely low expression. Peak expression observed within 12-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period. Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: larval carcass. Comments on Affy2 ProbeSet: ProbeSet 1641136_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of Cpr78Cc. Gene sequence location is 3L:21293680..21294271.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 78C6-78C6   Limits computationally determined from genome sequence between P{lacW}l(3)j1B10j1B10 and P{lacW}l(3)j2C4j2C4
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\Cpr78Cc for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.43 Gene model reviewed during 5.45
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) Cpr78Cc-RA FBtr0078338  NM_141043   522   119
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein Cpr78Cc-PA   FBpp0077994   12.7   119   3.93     NP_649300   AAF51703
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Insect cuticle protein (IPR000618)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE014296 AAF51703   AI295980   AI467769   AY113448 AAM29453   BI235156   BI236110   CO297728   CO300930   CO306867   CO312123   CO341655   EC073975   EC213433   EC217505   EC226255   EC231110   EC233710   EC234599   GH754655   GH754887   GH756007   GH756258   GH757283   GH757723   GH757761   GH758991   GH774281   GH778097   GH780748   GH782484   GH784295   GH784352   GH789524   GH790466   GH791927   GH792085   GH796359   GH797662   GH797996   GH807755   GH809650   GH810863   GH819795   GH820189   GH821571   GH823644   GH827344   GH828184   GH828874   GH829255   GH829952   GH831354   GH834079   GH834482   GH835828   GH842865   GH843292   GH844709   GH846769   GH847494   GH848991   GH851361   GH852871   GH856489   GH863240   GH863955   GH866402   GH870426   GH870753   GH873167   GH877126   GH877834   GH880599   GH886531   GH890252   GH892236   GH892759   GH892861   GH893684   GH896852   GH896934   GH897895   GH900872   GH901313   GH904588   GH905042   GH908288   GH912501   GH916130   GH917718   GH928167   GH930037   GH933239   GH935712   GH937624   GH938823   GH939023   GH939967   GH940501
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9VP53
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
in situ Stage Tissue/Position (including subcellular localization) Reference embryonic stage 13 -- 16   embryonic dorsal epidermis   (Fisher et al., 2012) embryonic ventral epidermis   (Fisher et al., 2012)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: larval carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    2.825 Larval Midgut    10 Larval Hindgut    9.1 Larval Malpighian Tubules    3.4 Larval Fat Body    6.2 Larval Salivary Gland    4 Larval Trachea    32.85 Larval Carcass    1101.775 Adult Head    7 Adult Eye    4.725 Adult Brain    3.2 Adult Thoracic-Abdominal Ganglion    4.6 Adult Crop    1.6 Adult Midgut    3.7 Adult Hindgut    7.2 Adult Malpighian Tubules    6.8 Adult Fat Body    4.8 Adult Salivary Gland    5.8 Adult Heart    2.325 Adult VirginFemale Spermatheca    7.1 Adult InseminatedFemale Spermatheca    5.4 Adult Ovary    1.6 Adult Testis    23.4 Adult Male Accessory Gland    4.4 Adult Carcass    10.5 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    2.825 Larval Midgut    10 Larval Hindgut    9.1 Larval Malpighian Tubules    3.4 Larval Fat Body    6.2 Larval Salivary Gland    4 Larval Trachea    32.85 Larval Carcass  (1101.775) Adult Head    7 Adult Eye    4.725 Adult Brain    3.2 Adult Thoracic-Abdominal Ganglion    4.6 Adult Crop    1.6 Adult Midgut    3.7 Adult Hindgut    7.2 Adult Malpighian Tubules    6.8 Adult Fat Body    4.8 Adult Salivary Gland    5.8 Adult Heart    2.325 Adult VirginFemale Spermatheca    7.1 Adult InseminatedFemale Spermatheca    5.4 Adult Ovary    1.6 Adult Testis    23.4 Adult Male Accessory Gland    4.4 Adult Carcass    10.5 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    2.825 Larval Midgut    10 Larval Hindgut    9.1 Larval Malpighian Tubules    3.4 Larval Fat Body    6.2 Larval Salivary Gland    4 Larval Trachea    32.85 Larval Carcass  (1101.775) Adult Head    7 Adult Eye    4.725 Adult Brain    3.2 Adult Thoracic-Abdominal Ganglion    4.6 Adult Crop    1.6 Adult Midgut    3.7 Adult Hindgut    7.2 Adult Malpighian Tubules    6.8 Adult Fat Body    4.8 Adult Salivary Gland    5.8 Adult Heart    2.325 Adult VirginFemale Spermatheca    7.1 Adult InseminatedFemale Spermatheca    5.4 Adult Ovary    1.6 Adult Testis    23.4 Adult Male Accessory Gland    4.4 Adult Carcass    10.5 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    2.825 Larval Midgut    10 Larval Hindgut    9.1 Larval Malpighian Tubules    3.4 Larval Fat Body    6.2 Larval Salivary Gland    4 Larval Trachea    32.85 Larval Carcass    1101.775 Adult Head    7 Adult Eye    4.725 Adult Brain    3.2 Adult Thoracic-Abdominal Ganglion    4.6 Adult Crop    1.6 Adult Midgut    3.7 Adult Hindgut    7.2 Adult Malpighian Tubules    6.8 Adult Fat Body    4.8 Adult Salivary Gland    5.8 Adult Heart    2.325 Adult VirginFemale Spermatheca    7.1 Adult InseminatedFemale Spermatheca    5.4 Adult Ovary    1.6 Adult Testis    23.4 Adult Male Accessory Gland    4.4 Adult Carcass    10.5 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    2.825 Larval Midgut    10 Larval Hindgut    9.1 Larval Malpighian Tubules    3.4 Larval Fat Body    6.2 Larval Salivary Gland    4 Larval Trachea    32.85 Larval Carcass    1101.775 Adult Head    7 Adult Eye    4.725 Adult Brain    3.2 Adult Thoracic-Abdominal Ganglion    4.6 Adult Crop    1.6 Adult Midgut    3.7 Adult Hindgut    7.2 Adult Malpighian Tubules    6.8 Adult Fat Body    4.8 Adult Salivary Gland    5.8 Adult Heart    2.325 Adult VirginFemale Spermatheca    7.1 Adult InseminatedFemale Spermatheca    5.4 Adult Ovary    1.6 Adult Testis    23.4 Adult Male Accessory Gland    4.4 Adult Carcass    10.5 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    2.825 Larval Midgut    10 Larval Hindgut    9.1 Larval Malpighian Tubules    3.4 Larval Fat Body    6.2 Larval Salivary Gland    4 Larval Trachea    32.85 Larval Carcass  (1101.775) Adult Head    7 Adult Eye    4.725 Adult Brain    3.2 Adult Thoracic-Abdominal Ganglion    4.6 Adult Crop    1.6 Adult Midgut    3.7 Adult Hindgut    7.2 Adult Malpighian Tubules    6.8 Adult Fat Body    4.8 Adult Salivary Gland    5.8 Adult Heart    2.325 Adult VirginFemale Spermatheca    7.1 Adult InseminatedFemale Spermatheca    5.4 Adult Ovary    1.6 Adult Testis    23.4 Adult Male Accessory Gland    4.4 Adult Carcass    10.5 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    2.825 Larval Midgut    10 Larval Hindgut    9.1 Larval Malpighian Tubules    3.4 Larval Fat Body    6.2 Larval Salivary Gland    4 Larval Trachea    32.85 Larval Carcass  1101.775 Adult Head    7 Adult Eye    4.725 Adult Brain    3.2 Adult Thoracic-Abdominal Ganglion    4.6 Adult Crop    1.6 Adult Midgut    3.7 Adult Hindgut    7.2 Adult Malpighian Tubules    6.8 Adult Fat Body    4.8 Adult Salivary Gland    5.8 Adult Heart    2.325 Adult VirginFemale Spermatheca    7.1 Adult InseminatedFemale Spermatheca    5.4 Adult Ovary    1.6 Adult Testis    23.4 Adult Male Accessory Gland    4.4 Adult Carcass    10.5 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    2.825 Larval Midgut    10 Larval Hindgut    9.1 Larval Malpighian Tubules    3.4 Larval Fat Body    6.2 Larval Salivary Gland    4 Larval Trachea    32.85 Larval Carcass    1101.775 Adult Head    7 Adult Eye    4.725 Adult Brain    3.2 Adult Thoracic-Abdominal Ganglion    4.6 Adult Crop    1.6 Adult Midgut    3.7 Adult Hindgut    7.2 Adult Malpighian Tubules    6.8 Adult Fat Body    4.8 Adult Salivary Gland    5.8 Adult Heart    2.325 Adult VirginFemale Spermatheca    7.1 Adult InseminatedFemale Spermatheca    5.4 Adult Ovary    1.6 Adult Testis    23.4 Adult Male Accessory Gland    4.4 Adult Carcass    10.5 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    7   NA  Eye    4.725   NA  Brain    3.2   2.825  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    4.6   NA  Crop    1.6   no informative data  Midgut    3.7   9.1  Hindgut    7.2   3.4  Malpighian Tubules    6.8   6.2  Fat Body    4.8   4  Salivary Gland    5.8   NA  Heart    2.325   no informative data  Trachea    NA   NA  VirginFemale Spermatheca    7.1   NA  InseminatedFemale Spermatheca    5.4   NA  Ovary    1.6   NA  Testis    23.4   NA  Male Accessory Gland    4.4   1101.775  Carcass    no informative data FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    7 central nervous system, larvae L3    0 central nervous system, pupae P8    4 head, virgin 1-day female    0 head, virgin 4-day female    0 head, virgin 20-day female    0 head, mated 1-day female    0 head, mated 4-day female    0 head, mated 20-day female    0 head, mated 1-day male    0 head, mated 4-day male    4 head, mated 20-day male    0 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    5 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    0 digestive system, 4-day adult    0 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    2 fat body, pupae P8    40 carcass, larvae L3 wandering    17 carcass, 1-day adult    0 carcass, 4-day adult    0 carcass, 20-day adult    0 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    14 accessory gland, mated 4-day male    2 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    7 central nervous system, larvae L3    0 central nervous system, pupae P8    4 head, virgin 1-day female    0 head, virgin 4-day female    0 head, virgin 20-day female    0 head, mated 1-day female    0 head, mated 4-day female    0 head, mated 20-day female    0 head, mated 1-day male    0 head, mated 4-day male    4 head, mated 20-day male    0 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    5 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    0 digestive system, 4-day adult    0 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    2 fat body, pupae P8  (40) carcass, larvae L3 wandering    17 carcass, 1-day adult    0 carcass, 4-day adult    0 carcass, 20-day adult    0 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    14 accessory gland, mated 4-day male    2 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    7 central nervous system, larvae L3    0 central nervous system, pupae P8    4 head, virgin 1-day female    0 head, virgin 4-day female    0 head, virgin 20-day female    0 head, mated 1-day female    0 head, mated 4-day female    0 head, mated 20-day female    0 head, mated 1-day male    0 head, mated 4-day male    4 head, mated 20-day male    0 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    5 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    0 digestive system, 4-day adult    0 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    2 fat body, pupae P8    40 carcass, larvae L3 wandering    17 carcass, 1-day adult    0 carcass, 4-day adult    0 carcass, 20-day adult    0 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    14 accessory gland, mated 4-day male    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    7 central nervous system, larvae L3    0 central nervous system, pupae P8    4 head, virgin 1-day female    0 head, virgin 4-day female    0 head, virgin 20-day female    0 head, mated 1-day female    0 head, mated 4-day female    0 head, mated 20-day female    0 head, mated 1-day male    0 head, mated 4-day male    4 head, mated 20-day male    0 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    5 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    0 digestive system, 4-day adult    0 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    2 fat body, pupae P8    40 carcass, larvae L3 wandering    17 carcass, 1-day adult    0 carcass, 4-day adult    0 carcass, 20-day adult    0 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    14 accessory gland, mated 4-day male    2 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    7 central nervous system, larvae L3    0 central nervous system, pupae P8    4 head, virgin 1-day female    0 head, virgin 4-day female    0 head, virgin 20-day female    0 head, mated 1-day female    0 head, mated 4-day female    0 head, mated 20-day female    0 head, mated 1-day male    0 head, mated 4-day male    4 head, mated 20-day male    0 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    5 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    0 digestive system, 4-day adult    0 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    2 fat body, pupae P8    40 carcass, larvae L3 wandering    17 carcass, 1-day adult    0 carcass, 4-day adult    0 carcass, 20-day adult    0 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    14 accessory gland, mated 4-day male    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    7 central nervous system, larvae L3    0 central nervous system, pupae P8    4 head, virgin 1-day female    0 head, virgin 4-day female    0 head, virgin 20-day female    0 head, mated 1-day female    0 head, mated 4-day female    0 head, mated 20-day female    0 head, mated 1-day male    0 head, mated 4-day male    4 head, mated 20-day male    0 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    5 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    0 digestive system, 4-day adult    0 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    2 fat body, pupae P8  (40) carcass, larvae L3 wandering    17 carcass, 1-day adult    0 carcass, 4-day adult    0 carcass, 20-day adult    0 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    14 accessory gland, mated 4-day male    2 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    7 central nervous system, larvae L3    0 central nervous system, pupae P8    4 head, virgin 1-day female    0 head, virgin 4-day female    0 head, virgin 20-day female    0 head, mated 1-day female    0 head, mated 4-day female    0 head, mated 20-day female    0 head, mated 1-day male    0 head, mated 4-day male    4 head, mated 20-day male    0 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    5 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    0 digestive system, 4-day adult    0 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    2 fat body, pupae P8    40 carcass, larvae L3 wandering    17 carcass, 1-day adult    0 carcass, 4-day adult    0 carcass, 20-day adult    0 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    14 accessory gland, mated 4-day male    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    7 central nervous system, larvae L3    0 central nervous system, pupae P8    4 head, virgin 1-day female    0 head, virgin 4-day female    0 head, virgin 20-day female    0 head, mated 1-day female    0 head, mated 4-day female    0 head, mated 20-day female    0 head, mated 1-day male    0 head, mated 4-day male    4 head, mated 20-day male    0 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    5 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    0 digestive system, 4-day adult    0 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    2 fat body, pupae P8    40 carcass, larvae L3 wandering    17 carcass, 1-day adult    0 carcass, 4-day adult    0 carcass, 20-day adult    0 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    14 accessory gland, mated 4-day male    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of extremely low expression. Peak expression observed within 12-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    1 embryo 02-04hr    2 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    2 embryo 10-12hr    2 embryo 12-14hr    1 embryo 14-16hr    19 embryo 16-18hr    211 embryo 18-20hr    690 embryo 20-22hr    589 embryo 22-24hr    517 larva L1    398 larva L2    139 larva L3 12hr old    729 larva L3 puffstage 1-2    211 larva L3 puffstage 3-6    19 larva L3 puffstage 7-9    2 white prepupae new    3 white prepupae 12hr    729 white prepupae 24hr    12 pupae 2d postWPP    32 pupae 3d postWPP    268 pupae 4d postWPP    8 adult male 01day    1 adult male 05day    2 adult male 30day    2 adult female 01day    0 adult female 05day    0 adult female 30day    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    1 embryo 02-04hr    2 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    2 embryo 10-12hr    2 embryo 12-14hr    1 embryo 14-16hr    19 embryo 16-18hr  (211) embryo 18-20hr  (690) embryo 20-22hr  (589) embryo 22-24hr  (517) larva L1  (398) larva L2  (139) larva L3 12hr old  (729) larva L3 puffstage 1-2  (211) larva L3 puffstage 3-6    19 larva L3 puffstage 7-9    2 white prepupae new    3 white prepupae 12hr  (729) white prepupae 24hr    12 pupae 2d postWPP  (32) pupae 3d postWPP  (268) pupae 4d postWPP    8 adult male 01day    1 adult male 05day    2 adult male 30day    2 adult female 01day    0 adult female 05day    0 adult female 30day    0 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    1 embryo 02-04hr    2 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    2 embryo 10-12hr    2 embryo 12-14hr    1 embryo 14-16hr    19 embryo 16-18hr  (211) embryo 18-20hr  (690) embryo 20-22hr  (589) embryo 22-24hr  (517) larva L1  (398) larva L2  (139) larva L3 12hr old  (729) larva L3 puffstage 1-2  (211) larva L3 puffstage 3-6    19 larva L3 puffstage 7-9    2 white prepupae new    3 white prepupae 12hr  (729) white prepupae 24hr    12 pupae 2d postWPP    32 pupae 3d postWPP  (268) pupae 4d postWPP    8 adult male 01day    1 adult male 05day    2 adult male 30day    2 adult female 01day    0 adult female 05day    0 adult female 30day    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    1 embryo 02-04hr    2 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    2 embryo 10-12hr    2 embryo 12-14hr    1 embryo 14-16hr    19 embryo 16-18hr    211 embryo 18-20hr    690 embryo 20-22hr    589 embryo 22-24hr    517 larva L1    398 larva L2    139 larva L3 12hr old    729 larva L3 puffstage 1-2    211 larva L3 puffstage 3-6    19 larva L3 puffstage 7-9    2 white prepupae new    3 white prepupae 12hr    729 white prepupae 24hr    12 pupae 2d postWPP    32 pupae 3d postWPP    268 pupae 4d postWPP    8 adult male 01day    1 adult male 05day    2 adult male 30day    2 adult female 01day    0 adult female 05day    0 adult female 30day    0 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    1 embryo 02-04hr    2 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    2 embryo 10-12hr    2 embryo 12-14hr    1 embryo 14-16hr    19 embryo 16-18hr    211 embryo 18-20hr    690 embryo 20-22hr    589 embryo 22-24hr    517 larva L1    398 larva L2    139 larva L3 12hr old    729 larva L3 puffstage 1-2    211 larva L3 puffstage 3-6    19 larva L3 puffstage 7-9    2 white prepupae new    3 white prepupae 12hr    729 white prepupae 24hr    12 pupae 2d postWPP    32 pupae 3d postWPP    268 pupae 4d postWPP    8 adult male 01day    1 adult male 05day    2 adult male 30day    2 adult female 01day    0 adult female 05day    0 adult female 30day    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    1 embryo 02-04hr    2 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    2 embryo 10-12hr    2 embryo 12-14hr    1 embryo 14-16hr    19 embryo 16-18hr  (211) embryo 18-20hr  (690) embryo 20-22hr  (589) embryo 22-24hr  (517) larva L1  (398) larva L2  (139) larva L3 12hr old  (729) larva L3 puffstage 1-2  (211) larva L3 puffstage 3-6    19 larva L3 puffstage 7-9    2 white prepupae new    3 white prepupae 12hr  (729) white prepupae 24hr    12 pupae 2d postWPP  32 pupae 3d postWPP  (268) pupae 4d postWPP    8 adult male 01day    1 adult male 05day    2 adult male 30day    2 adult female 01day    0 adult female 05day    0 adult female 30day    0 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    1 embryo 02-04hr    2 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    2 embryo 10-12hr    2 embryo 12-14hr    1 embryo 14-16hr    19 embryo 16-18hr  (211) embryo 18-20hr  (690) embryo 20-22hr  (589) embryo 22-24hr  (517) larva L1  (398) larva L2  139 larva L3 12hr old  (729) larva L3 puffstage 1-2  (211) larva L3 puffstage 3-6    19 larva L3 puffstage 7-9    2 white prepupae new    3 white prepupae 12hr  (729) white prepupae 24hr    12 pupae 2d postWPP    32 pupae 3d postWPP  (268) pupae 4d postWPP    8 adult male 01day    1 adult male 05day    2 adult male 30day    2 adult female 01day    0 adult female 05day    0 adult female 30day    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    1 embryo 02-04hr    2 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    2 embryo 10-12hr    2 embryo 12-14hr    1 embryo 14-16hr    19 embryo 16-18hr    211 embryo 18-20hr    690 embryo 20-22hr    589 embryo 22-24hr    517 larva L1    398 larva L2    139 larva L3 12hr old    729 larva L3 puffstage 1-2    211 larva L3 puffstage 3-6    19 larva L3 puffstage 7-9    2 white prepupae new    3 white prepupae 12hr    729 white prepupae 24hr    12 pupae 2d postWPP    32 pupae 3d postWPP    268 pupae 4d postWPP    8 adult male 01day    1 adult male 05day    2 adult male 30day    2 adult female 01day    0 adult female 05day    0 adult female 30day    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    0 embryonic 1182-4H    0 embryonic GM2    0 embryonic Kc167    0 embryonic S1    0 embryonic S3    0 leg disc CME L1    1 wing disc CME-W2    0 wing disc ML-DmD8    0 wing disc ML-DmD9    0 wing disc ML-DmD16-c3    0 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    0 antennal disc ML-DmD20-c5    0 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    0 tumorous blood cells mbn2    0 ovary fGS/OSS    0 ovary OSC    0 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    0 embryonic 1182-4H    0 embryonic GM2    0 embryonic Kc167    0 embryonic S1    0 embryonic S3    0 leg disc CME L1    1 wing disc CME-W2    0 wing disc ML-DmD8    0 wing disc ML-DmD9    0 wing disc ML-DmD16-c3    0 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    0 antennal disc ML-DmD20-c5    0 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    0 tumorous blood cells mbn2    0 ovary fGS/OSS    0 ovary OSC    0 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    0 embryonic 1182-4H    0 embryonic GM2    0 embryonic Kc167    0 embryonic S1    0 embryonic S3    0 leg disc CME L1    1 wing disc CME-W2    0 wing disc ML-DmD8    0 wing disc ML-DmD9    0 wing disc ML-DmD16-c3    0 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    0 antennal disc ML-DmD20-c5    0 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    0 tumorous blood cells mbn2    0 ovary fGS/OSS    0 ovary OSC    0 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    0 embryonic 1182-4H    0 embryonic GM2    0 embryonic Kc167    0 embryonic S1    0 embryonic S3    0 leg disc CME L1    1 wing disc CME-W2    0 wing disc ML-DmD8    0 wing disc ML-DmD9    0 wing disc ML-DmD16-c3    0 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    0 antennal disc ML-DmD20-c5    0 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    0 tumorous blood cells mbn2    0 ovary fGS/OSS    0 ovary OSC    0 ovary OSS    0 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    0 embryonic 1182-4H    0 embryonic GM2    0 embryonic Kc167    0 embryonic S1    0 embryonic S3    0 leg disc CME L1    1 wing disc CME-W2    0 wing disc ML-DmD8    0 wing disc ML-DmD9    0 wing disc ML-DmD16-c3    0 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    0 antennal disc ML-DmD20-c5    0 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    0 tumorous blood cells mbn2    0 ovary fGS/OSS    0 ovary OSC    0 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    0 embryonic 1182-4H    0 embryonic GM2    0 embryonic Kc167    0 embryonic S1    0 embryonic S3    0 leg disc CME L1    1 wing disc CME-W2    0 wing disc ML-DmD8    0 wing disc ML-DmD9    0 wing disc ML-DmD16-c3    0 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    0 antennal disc ML-DmD20-c5    0 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    0 tumorous blood cells mbn2    0 ovary fGS/OSS    0 ovary OSC    0 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    0 embryonic 1182-4H    0 embryonic GM2    0 embryonic Kc167    0 embryonic S1    0 embryonic S3    0 leg disc CME L1    1 wing disc CME-W2    0 wing disc ML-DmD8    0 wing disc ML-DmD9    0 wing disc ML-DmD16-c3    0 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    0 antennal disc ML-DmD20-c5    0 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    0 tumorous blood cells mbn2    0 ovary fGS/OSS    0 ovary OSC    0 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    0 embryonic 1182-4H    0 embryonic GM2    0 embryonic Kc167    0 embryonic S1    0 embryonic S3    0 leg disc CME L1    1 wing disc CME-W2    0 wing disc ML-DmD8    0 wing disc ML-DmD9    0 wing disc ML-DmD16-c3    0 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    0 antennal disc ML-DmD20-c5    0 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    0 tumorous blood cells mbn2    0 ovary fGS/OSS    0 ovary OSC    0 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    1 cold shock, 4-day adult    1 heat shock, 4-day adult    202 Cadmium 50 mM 6 hrs, larvae L3    622 Cadmium 50 mM 12 hrs, larvae L3    181 Cadmium 50 mM 48 hrs, 4-day adult    243 Cadmium 100 mM 48 hrs, 4-day adult    4 Copper 0.5 mM 12 hrs, larvae L3    358 Copper 15 mM 48 hrs, 4-day adult    12 Zinc 5 mM 12 hrs, larvae L3    428 Zinc 4.5 mM 48 hrs, 4-day adult    23 Ethanol 2.5% 3 hrs, larvae L3    2 Ethanol 5% 3 hrs, larvae L3    247 Ethanol 10% 3 hrs, larvae L3    342 Caffeine 1.5 mg/ml 4 hrs, larvae L3    180 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    4 Caffeine 25 mg/ml 48 hrs, 4-day adult    34 Paraquat 5 mM 48 hrs, 4-day adult    15 Paraquat 10 mM 48 hrs, 4-day adult    6 Rotenone 2 μg 12 hrs, larvae L3    209 Rotenone 8 μg 12 hrs, larvae L3    346 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    1 cold shock, 4-day adult    1 heat shock, 4-day adult  (202) Cadmium 50 mM 6 hrs, larvae L3  (622) Cadmium 50 mM 12 hrs, larvae L3  (181) Cadmium 50 mM 48 hrs, 4-day adult  (243) Cadmium 100 mM 48 hrs, 4-day adult    4 Copper 0.5 mM 12 hrs, larvae L3  (358) Copper 15 mM 48 hrs, 4-day adult    12 Zinc 5 mM 12 hrs, larvae L3  (428) Zinc 4.5 mM 48 hrs, 4-day adult    23 Ethanol 2.5% 3 hrs, larvae L3    2 Ethanol 5% 3 hrs, larvae L3  (247) Ethanol 10% 3 hrs, larvae L3  (342) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (180) Caffeine 2.5 mg/ml 48 hrs, 4-day adult    4 Caffeine 25 mg/ml 48 hrs, 4-day adult  (34) Paraquat 5 mM 48 hrs, 4-day adult    15 Paraquat 10 mM 48 hrs, 4-day adult    6 Rotenone 2 μg 12 hrs, larvae L3  (209) Rotenone 8 μg 12 hrs, larvae L3  (346) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    1 cold shock, 4-day adult    1 heat shock, 4-day adult  (202) Cadmium 50 mM 6 hrs, larvae L3  (622) Cadmium 50 mM 12 hrs, larvae L3  (181) Cadmium 50 mM 48 hrs, 4-day adult  (243) Cadmium 100 mM 48 hrs, 4-day adult    4 Copper 0.5 mM 12 hrs, larvae L3  (358) Copper 15 mM 48 hrs, 4-day adult    12 Zinc 5 mM 12 hrs, larvae L3  (428) Zinc 4.5 mM 48 hrs, 4-day adult    23 Ethanol 2.5% 3 hrs, larvae L3    2 Ethanol 5% 3 hrs, larvae L3  (247) Ethanol 10% 3 hrs, larvae L3  (342) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (180) Caffeine 2.5 mg/ml 48 hrs, 4-day adult    4 Caffeine 25 mg/ml 48 hrs, 4-day adult    34 Paraquat 5 mM 48 hrs, 4-day adult    15 Paraquat 10 mM 48 hrs, 4-day adult    6 Rotenone 2 μg 12 hrs, larvae L3  (209) Rotenone 8 μg 12 hrs, larvae L3  (346) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    1 cold shock, 4-day adult    1 heat shock, 4-day adult    202 Cadmium 50 mM 6 hrs, larvae L3    622 Cadmium 50 mM 12 hrs, larvae L3    181 Cadmium 50 mM 48 hrs, 4-day adult    243 Cadmium 100 mM 48 hrs, 4-day adult    4 Copper 0.5 mM 12 hrs, larvae L3    358 Copper 15 mM 48 hrs, 4-day adult    12 Zinc 5 mM 12 hrs, larvae L3    428 Zinc 4.5 mM 48 hrs, 4-day adult    23 Ethanol 2.5% 3 hrs, larvae L3    2 Ethanol 5% 3 hrs, larvae L3    247 Ethanol 10% 3 hrs, larvae L3    342 Caffeine 1.5 mg/ml 4 hrs, larvae L3    180 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    4 Caffeine 25 mg/ml 48 hrs, 4-day adult    34 Paraquat 5 mM 48 hrs, 4-day adult    15 Paraquat 10 mM 48 hrs, 4-day adult    6 Rotenone 2 μg 12 hrs, larvae L3    209 Rotenone 8 μg 12 hrs, larvae L3    346 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    1 cold shock, 4-day adult    1 heat shock, 4-day adult    202 Cadmium 50 mM 6 hrs, larvae L3    622 Cadmium 50 mM 12 hrs, larvae L3    181 Cadmium 50 mM 48 hrs, 4-day adult    243 Cadmium 100 mM 48 hrs, 4-day adult    4 Copper 0.5 mM 12 hrs, larvae L3    358 Copper 15 mM 48 hrs, 4-day adult    12 Zinc 5 mM 12 hrs, larvae L3    428 Zinc 4.5 mM 48 hrs, 4-day adult    23 Ethanol 2.5% 3 hrs, larvae L3    2 Ethanol 5% 3 hrs, larvae L3    247 Ethanol 10% 3 hrs, larvae L3    342 Caffeine 1.5 mg/ml 4 hrs, larvae L3    180 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    4 Caffeine 25 mg/ml 48 hrs, 4-day adult    34 Paraquat 5 mM 48 hrs, 4-day adult    15 Paraquat 10 mM 48 hrs, 4-day adult    6 Rotenone 2 μg 12 hrs, larvae L3    209 Rotenone 8 μg 12 hrs, larvae L3    346 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    1 cold shock, 4-day adult    1 heat shock, 4-day adult  (202) Cadmium 50 mM 6 hrs, larvae L3  (622) Cadmium 50 mM 12 hrs, larvae L3  (181) Cadmium 50 mM 48 hrs, 4-day adult  (243) Cadmium 100 mM 48 hrs, 4-day adult    4 Copper 0.5 mM 12 hrs, larvae L3  (358) Copper 15 mM 48 hrs, 4-day adult    12 Zinc 5 mM 12 hrs, larvae L3  (428) Zinc 4.5 mM 48 hrs, 4-day adult    23 Ethanol 2.5% 3 hrs, larvae L3    2 Ethanol 5% 3 hrs, larvae L3  (247) Ethanol 10% 3 hrs, larvae L3  (342) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (180) Caffeine 2.5 mg/ml 48 hrs, 4-day adult    4 Caffeine 25 mg/ml 48 hrs, 4-day adult  (34) Paraquat 5 mM 48 hrs, 4-day adult    15 Paraquat 10 mM 48 hrs, 4-day adult    6 Rotenone 2 μg 12 hrs, larvae L3  (209) Rotenone 8 μg 12 hrs, larvae L3  (346) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    1 cold shock, 4-day adult    1 heat shock, 4-day adult  (202) Cadmium 50 mM 6 hrs, larvae L3  (622) Cadmium 50 mM 12 hrs, larvae L3  (181) Cadmium 50 mM 48 hrs, 4-day adult  (243) Cadmium 100 mM 48 hrs, 4-day adult    4 Copper 0.5 mM 12 hrs, larvae L3  (358) Copper 15 mM 48 hrs, 4-day adult    12 Zinc 5 mM 12 hrs, larvae L3  (428) Zinc 4.5 mM 48 hrs, 4-day adult    23 Ethanol 2.5% 3 hrs, larvae L3    2 Ethanol 5% 3 hrs, larvae L3  (247) Ethanol 10% 3 hrs, larvae L3  (342) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (180) Caffeine 2.5 mg/ml 48 hrs, 4-day adult    4 Caffeine 25 mg/ml 48 hrs, 4-day adult    34 Paraquat 5 mM 48 hrs, 4-day adult    15 Paraquat 10 mM 48 hrs, 4-day adult    6 Rotenone 2 μg 12 hrs, larvae L3  (209) Rotenone 8 μg 12 hrs, larvae L3  (346) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    1 cold shock, 4-day adult    1 heat shock, 4-day adult    202 Cadmium 50 mM 6 hrs, larvae L3    622 Cadmium 50 mM 12 hrs, larvae L3    181 Cadmium 50 mM 48 hrs, 4-day adult    243 Cadmium 100 mM 48 hrs, 4-day adult    4 Copper 0.5 mM 12 hrs, larvae L3    358 Copper 15 mM 48 hrs, 4-day adult    12 Zinc 5 mM 12 hrs, larvae L3    428 Zinc 4.5 mM 48 hrs, 4-day adult    23 Ethanol 2.5% 3 hrs, larvae L3    2 Ethanol 5% 3 hrs, larvae L3    247 Ethanol 10% 3 hrs, larvae L3    342 Caffeine 1.5 mg/ml 4 hrs, larvae L3    180 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    4 Caffeine 25 mg/ml 48 hrs, 4-day adult    34 Paraquat 5 mM 48 hrs, 4-day adult    15 Paraquat 10 mM 48 hrs, 4-day adult    6 Rotenone 2 μg 12 hrs, larvae L3    209 Rotenone 8 μg 12 hrs, larvae L3    346 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_12 mE1_20_mRNA_expression_cluster_12
External Data & Images
Linkouts	BDGP expression data • RE32113 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0037069 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG7658-RA FlyExpress - Embryonic expression images (BDGP data) • Show all FlyExpress processed images for Cpr78Cc Stages(s) 13-16
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable, with Scer\GAL4pnr-MD237 Cpr78CcGD5546 Phenotype manifest in Allele
Classical Alleles ( 0 )
For All Classical Alleles Show
Allele of Cpr78Cc Class Mutagen Stocks Known lesion
Alleles Carried on Transgenic Constructs ( 2 )
For All Alleles Carried on Transgenic Constructs Show
Allele of Cpr78Cc Class Mutagen Stocks Known lesion Cpr78CcGD5546 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes Cpr78CcKK104238 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD5546} NA P{KK104238} NA
Insertions
	Type of insertions Name Expression data
Gene Ontology: Function, Process & Cellular Component ( 2 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 2 terms )
Molecular Function
CV term Evidence References
structural constituent of chitin-based cuticle inferred from sequence or structural similarity with InterPro:IPR000618 (Willis, 2007.1.3) inferred from sequence or structural similarity with Pfam:PF00379 (Willis, 2007.1.3) structural constituent of chitin-based larval cuticle inferred from sequence or structural similarity with UniProtKB:O02387 (FlyBase, 1992-)
Biological Process ( 0 terms)
Cellular Component ( 0 terms)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions Cpr78Cc allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 65603 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0037069 DroID - A comprehensive database of gene and protein interactions. • FBgn0037069 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 40355
Orthologs
OrthoDB Orthologs (241) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6S4Q2V Dipteran inclusive ortholog search EOG6R7VM9 Insect inclusive ortholog search EOG6KKX13 Arthropod inclusive ortholog search EOG63R24R Metazoa inclusive ortholog search No orthologs identified
Orthologs in Drosophila Species (EOG6S4Q2V)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\Cpr78Cc     Drosophila simulans   Dsim\GD14949 Y   Drosophila sechellia   Dsec\GM22355 Y   Drosophila erecta   Dere\GG16171 Y   Drosophila yakuba   Dyak\GE19741 Y   Drosophila yakuba   Dyak\GE23051     Drosophila ananassae   Dana\GF10274 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA23947     Drosophila pseudoobscura pseudoobscura   Dpse\GA20507 Y   Drosophila persimilis   Dper\GL24678     Drosophila persimilis   Dper\GL24679 Y   Drosophila willistoni   Dwil\GK20466 Y   Drosophila virilis   Dvir\GJ13281 Y   Drosophila mojavensis   Dmoj\GI12010 Y   Drosophila grimshawi   Dgri\GH15299 Y
Orthologs in non-Drosophila Dipterans (EOG6R7VM9)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL008872
Orthologs in non-Dipteran Insects (EOG6KKX13)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\GB47906 Y Apis mellifera Western honey bee  Amel\LOC724649 Y Apis mellifera Western honey bee  Amel\CPR12 Y Apis mellifera Western honey bee  Amel\GB46298 Y Apis mellifera Western honey bee  Amel\GB52161 Y Apis mellifera Western honey bee  Amel\CPR13 Y Apis mellifera Western honey bee  Amel\GB47903 Y Apis mellifera Western honey bee  Amel\GB42612 Y Apis mellifera Western honey bee  Amel\GB43670 Y Apis mellifera Western honey bee  Amel\GB46297 Y Apis mellifera Western honey bee  Amel\GB47902 Y Apis mellifera Western honey bee  Amel\GB46312 Y Apis mellifera Western honey bee  Amel\GB46299 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG006503 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG006859 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG005393 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG006863 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG013411 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG013416 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG006864 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG010389 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG010007 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG006867 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG016022 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG013414 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG013417 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG007522 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG006861 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG010008 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG006862 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG013413 Y Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH22753 Y Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH22751 Y Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH17027 Y Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH17029 Y Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH21414 Y Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH19798 Y Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH22756 Y Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH17028 Y Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH22755 Y Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH21415 Y Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH21416 Y Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH22752 Y Atta cephalotes Leafcutter ant  Acep\ACEP25267 Y Atta cephalotes Leafcutter ant  Acep\ACEP27437 Y Atta cephalotes Leafcutter ant  Acep\ACEP24251 Y Atta cephalotes Leafcutter ant  Acep\ACEP17449 Y Atta cephalotes Leafcutter ant  Acep\ACEP27431 Y Atta cephalotes Leafcutter ant  Acep\ACEP25266 Y Atta cephalotes Leafcutter ant  Acep\ACEP24250 Y Atta cephalotes Leafcutter ant  Acep\ACEP27444 Y Atta cephalotes Leafcutter ant  Acep\ACEP27432 Y Atta cephalotes Leafcutter ant  Acep\ACEP25277 Y Atta cephalotes Leafcutter ant  Acep\ACEP24236 Y Atta cephalotes Leafcutter ant  Acep\ACEP25265 Y Atta cephalotes Leafcutter ant  Acep\ACEP27427 Y Camponotus floridanus Florida carpenter ant  Cflo\CFLO21033 Y Camponotus floridanus Florida carpenter ant  Cflo\CFLO14804 Y Camponotus floridanus Florida carpenter ant  Cflo\CFLO21024 Y Camponotus floridanus Florida carpenter ant  Cflo\CFLO21020 Y Camponotus floridanus Florida carpenter ant  Cflo\CFLO20940 Y Camponotus floridanus Florida carpenter ant  Cflo\CFLO15374 Y Camponotus floridanus Florida carpenter ant  Cflo\CFLO20939 Y Camponotus floridanus Florida carpenter ant  Cflo\CFLO21032 Y Camponotus floridanus Florida carpenter ant  Cflo\CFLO21025 Y Camponotus floridanus Florida carpenter ant  Cflo\CFLO20958 Y Camponotus floridanus Florida carpenter ant  Cflo\CFLO21019 Y Camponotus floridanus Florida carpenter ant  Cflo\CFLO21021 Y Camponotus floridanus Florida carpenter ant  Cflo\CFLO14803 Y Camponotus floridanus Florida carpenter ant  Cflo\CFLO14802 Y Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL21887 Y Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL21889 Y Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL20594 Y Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL20587 Y Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL19362 Y Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL20586 Y Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL19363 Y Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL20593 Y Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL20772 Y Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL19364 Y Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL21888 Y Linepithema humile Argentine ant  Lhum\LH23807 Y Linepithema humile Argentine ant  Lhum\LH19211 Y Linepithema humile Argentine ant  Lhum\LH16388 Y Linepithema humile Argentine ant  Lhum\LH16391 Y Linepithema humile Argentine ant  Lhum\LH19218 Y Linepithema humile Argentine ant  Lhum\LH16383 Y Linepithema humile Argentine ant  Lhum\LH10870 Y Linepithema humile Argentine ant  Lhum\LH24581 Y Linepithema humile Argentine ant  Lhum\LH24582 Y Linepithema humile Argentine ant  Lhum\LH16382 Y Linepithema humile Argentine ant  Lhum\LH24583 Y Pogonomyrmex barbatus Red harvester ant  Pbar\PB20785 Y Pogonomyrmex barbatus Red harvester ant  Pbar\PB14690 Y Pogonomyrmex barbatus Red harvester ant  Pbar\PB18423 Y Pogonomyrmex barbatus Red harvester ant  Pbar\PB14691 Y Pogonomyrmex barbatus Red harvester ant  Pbar\PB18425 Y Pogonomyrmex barbatus Red harvester ant  Pbar\PB14673 Y Pogonomyrmex barbatus Red harvester ant  Pbar\PB20784 Y Pogonomyrmex barbatus Red harvester ant  Pbar\PB14688 Y Pogonomyrmex barbatus Red harvester ant  Pbar\PB20800 Y Pogonomyrmex barbatus Red harvester ant  Pbar\PB24199 Y Pogonomyrmex barbatus Red harvester ant  Pbar\PB14682 Y Pogonomyrmex barbatus Red harvester ant  Pbar\PB20794 Y Solenopsis invicta Red fire ant  Sinv\SINV25632 Y Solenopsis invicta Red fire ant  Sinv\SINV21745 Y Solenopsis invicta Red fire ant  Sinv\SINV21730 Y Solenopsis invicta Red fire ant  Sinv\SINV25026 Y Solenopsis invicta Red fire ant  Sinv\SINV16553 Y Solenopsis invicta Red fire ant  Sinv\SINV21768 Y Solenopsis invicta Red fire ant  Sinv\SINV25020 Y Solenopsis invicta Red fire ant  Sinv\SINV25023 Y Solenopsis invicta Red fire ant  Sinv\SINV16530 Y Solenopsis invicta Red fire ant  Sinv\SINV21761 Y Acyrthosiphon pisum Pea aphid  Apim\ACYPI009006 Y Acyrthosiphon pisum Pea aphid  Apim\ACYPI066082 Y Acyrthosiphon pisum Pea aphid  Apim\ACYPI003649 Y Acyrthosiphon pisum Pea aphid  Apim\ACYPI001610 Y Acyrthosiphon pisum Pea aphid  Apim\ACYPI005591 Y Acyrthosiphon pisum Pea aphid  Apim\ACYPI001775 Y Bombyx mori Silkmoth  Bmor\BmorCPR23 Y Bombyx mori Silkmoth  Bmor\BmorCPR39 Y Bombyx mori Silkmoth  Bmor\BmorCPR6 Y Bombyx mori Silkmoth  Bmor\BmorCPR33 Y Bombyx mori Silkmoth  Bmor\BGIBMGA000340 Y Bombyx mori Silkmoth  Bmor\BmorCPR26 Y Bombyx mori Silkmoth  Bmor\BmorCPR37 Y Bombyx mori Silkmoth  Bmor\BGIBMGA007015 Y Bombyx mori Silkmoth  Bmor\BmorCPR7 Y Bombyx mori Silkmoth  Bmor\BmorCPR24 Y Bombyx mori Silkmoth  Bmor\BmorCPR4 Y Bombyx mori Silkmoth  Bmor\BGIBMGA000341 Y Bombyx mori Silkmoth  Bmor\BmorCPR34 Y Bombyx mori Silkmoth  Bmor\BmorCPR27 Y Bombyx mori Silkmoth  Bmor\BmorCPR18 Y Bombyx mori Silkmoth  Bmor\BGIBMGA002549 Y Bombyx mori Silkmoth  Bmor\BmorCPR38 Y Bombyx mori Silkmoth  Bmor\BmorCPR43 Y Bombyx mori Silkmoth  Bmor\BmorCPR42 Y Bombyx mori Silkmoth  Bmor\BmorCPR32 Y Bombyx mori Silkmoth  Bmor\BmorCPR49 Y Bombyx mori Silkmoth  Bmor\BmorCPR13 Y Bombyx mori Silkmoth  Bmor\BmorCPR9 Y Bombyx mori Silkmoth  Bmor\BGIBMGA005277 Y Bombyx mori Silkmoth  Bmor\BmorCPR19 Y Pediculus humanus Human body louse  Phum\PHUM392770 Y Pediculus humanus Human body louse  Phum\PHUM605650 Y Pediculus humanus Human body louse  Phum\PHUM392750 Y Pediculus humanus Human body louse  Phum\PHUM605980 Y Pediculus humanus Human body louse  Phum\PHUM601840 Y Pediculus humanus Human body louse  Phum\PHUM606390 Y Pediculus humanus Human body louse  Phum\PHUM392730 Y Tribolium castaneum Red flour beetle  Tcas\TC013127 Y Tribolium castaneum Red flour beetle  Tcas\TC014500 Y Tribolium castaneum Red flour beetle  Tcas\TC014499 Y Tribolium castaneum Red flour beetle  Tcas\TC013131 Y Tribolium castaneum Red flour beetle  Tcas\TC014685 Y Tribolium castaneum Red flour beetle  Tcas\TC003831 Y Tribolium castaneum Red flour beetle  Tcas\TC013307 Y Tribolium castaneum Red flour beetle  Tcas\TC003834 Y Tribolium castaneum Red flour beetle  Tcas\TC013129 Y Tribolium castaneum Red flour beetle  Tcas\TC003832 Y Tribolium castaneum Red flour beetle  Tcas\TC014497 Y Tribolium castaneum Red flour beetle  Tcas\TC014770 Y Tribolium castaneum Red flour beetle  Tcas\TC013139 Y Tribolium castaneum Red flour beetle  Tcas\TC014771 Y Tribolium castaneum Red flour beetle  Tcas\TC013128 Y Tribolium castaneum Red flour beetle  Tcas\TC014498 Y Tribolium castaneum Red flour beetle  Tcas\TC014686 Y Tribolium castaneum Red flour beetle  Tcas\TC003830 Y Tribolium castaneum Red flour beetle  Tcas\TC003835 Y Tribolium castaneum Red flour beetle  Tcas\TC013138 Y Tribolium castaneum Red flour beetle  Tcas\TC004547 Y Tribolium castaneum Red flour beetle  Tcas\TC013130 Y Tribolium castaneum Red flour beetle  Tcas\TC013135 Y Tribolium castaneum Red flour beetle  Tcas\TC014720 Y Tribolium castaneum Red flour beetle  Tcas\TC002595 Y Tribolium castaneum Red flour beetle  Tcas\TC013126 Y Tribolium castaneum Red flour beetle  Tcas\TC004548 Y
Orthologs in non-Insect Arthropods (EOG63R24R)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\Map1d Y Daphnia pulex Water flea  Dpux\JGI_V11_253508 Y Daphnia pulex Water flea  Dpux\JGI_V11_58106 Y Daphnia pulex Water flea  Dpux\JGI_V11_263371 Y Daphnia pulex Water flea  Dpux\EF-1 alpha Y Daphnia pulex Water flea  Dpux\Psma3 Y Daphnia pulex Water flea  Dpux\MESK4 Y Daphnia pulex Water flea  Dpux\JGI_V11_60605 Y Daphnia pulex Water flea  Dpux\JGI_V11_303748 Y Daphnia pulex Water flea  Dpux\ycf9 Y Daphnia pulex Water flea  Dpux\Nktr Y Daphnia pulex Water flea  Dpux\JGI_V11_60650 Y Daphnia pulex Water flea  Dpux\JGI_V11_302740 Y Daphnia pulex Water flea  Dpux\JGI_V11_325416 Y Daphnia pulex Water flea  Dpux\PB2 Y Daphnia pulex Water flea  Dpux\JGI_V11_229448 Y Daphnia pulex Water flea  Dpux\JGI_V11_263370 Y Daphnia pulex Water flea  Dpux\JGI_V11_303733 Y Daphnia pulex Water flea  Dpux\JGI_V11_332302 Y Daphnia pulex Water flea  Dpux\JGI_V11_224365 Y Daphnia pulex Water flea  Dpux\JGI_V11_301237 Y Daphnia pulex Water flea  Dpux\Wbp4 Y Daphnia pulex Water flea  Dpux\JGI_V11_229447 Y Daphnia pulex Water flea  Dpux\CLDN25 Y Daphnia pulex Water flea  Dpux\ND1 Y Daphnia pulex Water flea  Dpux\JGI_V11_302183 Y Daphnia pulex Water flea  Dpux\JGI_V11_110014 Y Daphnia pulex Water flea  Dpux\mp20 Y Daphnia pulex Water flea  Dpux\JGI_V11_325539 Y Daphnia pulex Water flea  Dpux\JGI_V11_302739 Y Daphnia pulex Water flea  Dpux\JGI_V11_219079 Y Daphnia pulex Water flea  Dpux\Prc1 Y Daphnia pulex Water flea  Dpux\JGI_V11_109945 Y Daphnia pulex Water flea  Dpux\PB1-F2 Y Daphnia pulex Water flea  Dpux\JGI_V11_64995 Y Daphnia pulex Water flea  Dpux\JGI_V11_332314 Y Ixodes scapularis Deer tick  Isca\ISCW003132 Y Ixodes scapularis Deer tick  Isca\ISCW003791 Y Ixodes scapularis Deer tick  Isca\ISCW020944 Y Ixodes scapularis Deer tick  Isca\ISCW019775 Y Ixodes scapularis Deer tick  Isca\ISCW002954 Y Ixodes scapularis Deer tick  Isca\ISCW020943 Y Ixodes scapularis Deer tick  Isca\ISCW016302 Y Ixodes scapularis Deer tick  Isca\ISCW013798 Y Ixodes scapularis Deer tick  Isca\ISCW016310 Y Ixodes scapularis Deer tick  Isca\ISCW007107 Y
Orthologs in non-Arthropod Metazoa (None identified)
No non-Arthropod Metazoa orthologies identified
Human Orthologs (0)
Gene OMIM HGNC
AAA Orthologs (11) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD14949 Drosophila sechellia Dsec\GM22355 Drosophila erecta Dere\GG16171 Drosophila yakuba Dyak\GE19741 Drosophila ananassae Dana\GF10274 Drosophila pseudoobscura pseudoobscura Dpse\GA20507 Drosophila persimilis Dper\GL24679 Drosophila willistoni Dwil\GK20466 Drosophila virilis Dvir\GJ13281 Drosophila mojavensis Dmoj\GI12010 Drosophila grimshawi Dgri\GH15299
Stocks & Reagents
Stocks Listed in FlyBase ( 3 )
VDRC	v100410 P{KK104238}VIE-260B v31059 w1118; P{GD5546}v31059 v31060 w1118; P{GD5546}v31060/CyO
Genomic Clones ( 1 )
	BACR02C22 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 96 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	RE32113
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	LP09759 RE30967
Other clones	38760 54790 56892 99018 145312 CK01.12B.D8 CK01.102C.E7 EK170424 EK179715 EK227912 EK252632 EP12909 RP003034173 RP003037031 RP003043022 RP003052035 RP003081074 RP003085280 RP003089833 RP003092470 RP003107266 RP003127950 RP003137681 RP003170892 RP003200905 RP003201788 RP003209244 RP003209263 RP003217527 RP003225678 RP003227659 RP003229327 RP003230827 RP003236465 RP003239823 RP003242119 RP003260665 RP003262552 RP003269120 RP003272535 RP003273094 RP003274611 RP003275926 RP003281116 RP003284982 RP003307782 RP003310815 RP003318624 RP003331671 RP003332930 RP003339499 RP003345599 RP003347957 RP003354538 RP003355803 RP003380435 RP003381194 RP003383718 RP003418376 RP003422278 RP003432120 RP003437918 RP003448437 RP003461102 RP003469921 RP003481727 RP003498039 RP003505844 RP003513691 RP003519451 RP003540508 RP003563919 RP003568446 RP003572643 RP003576119 RP003577537 RP003591149 RP003593126 RP003596523 RP003596866 RP003598831 RP003603943 RP003603988 RP003604109 RP003614110 RP003620890 RP003621843 RP003646715 RP003647275 RP003656766 RP003659476 RP003667824 RP003682768
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0037069 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 40355
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of	Source for identity of: Cpr78Cc CG7658 (Willis, 2007.1.3)
Source for database merge of	Source for merge of: CG7658 anon-EST:ParkEST167 (Bayraktaroglu, 2000.11.2) Source for merge of: CG7658 BcDNA:RE32113 (FlyBase, 1996-)
Additional comments	Source for merge of CG7658 BcDNA:RE32113 was a shared cDNA (date:030728). (FlyBase, 1996-)
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_141043 RefSeq (Proteins) • NP_649300 DDBJ / EMBL / GenBank • AAF51703 AAM29453 AI467769 AY113448 BI236110 Entrez Gene - A searchable database of RefSeq genes. • 40355 UniProtKB/TrEMBL • Q9VP53
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Insect cuticle protein (IPR000618) BDGP expression data - Patterns of gene expression in Drosophila embryogenesis • RE32113
Linkouts
	BioGRID - A database of protein and genetic interactions • 65603 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0037069 DroID - A comprehensive database of gene and protein interactions. • FBgn0037069 DRSC - Results from RNAi screens. • FBgn0037069 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0037069 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG7658-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0037069 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 40355 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 40355 modMine - Data generated by the modENCODE project. • FBgn0037069
Synonyms & Secondary IDs ( 6 )
Reported As
Symbol Synonym	anon-EST:ParkEST167   BcDNA:RE32113   CG7658 (Keleman et al., 2009.8.5, Blanco et al., 2008) Cpr78Cc (Willis, 2007.1.3, Karouzou et al., 2007, Karouzou et al., 2007, Sharma et al., 2011, Cherbas et al., 2011) DmelCpr78Cc (Karouzou et al., 2007)
Name Synonym	CG7658   Cuticular protein 78Cc
Secondary FlyBase IDs
	FBgn0026291 FBgn0063036
References ( 20 )
Research paper	Cherbas et al., 2011, Genome Res. 21(2): 301--314 The transcriptional diversity of 25 Drosophila cell lines. [FBrf0213077] Sharma et al., 2011, Chemosphere 82(3): 370--376 Transcriptome analysis provides insights for understanding the adverse effects of endosulfan in Drosophila melanogaster. [FBrf0212610] Blanco et al., 2008, Genome Biol. 9(9): R134 Conserved chromosomal clustering of genes governed by chromatin regulators in Drosophila. [FBrf0207036]
Supplementary material	Graveley et al., 2011, Nature 471(7339): Supplementary Table 33. Fuzzy Cluster Members. [FBrf0213980] The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518] Karouzou et al., 2007, Insect Biochem. Mol. Biol. 37(8): Table S1. [FBrf0200185] Karouzou et al., 2007, Insect Biochem. Mol. Biol. 37(8): Tables S2-S5. [FBrf0200186] Giot et al., 2003, Science 302(5651): Tables S1 to S7. [FBrf0166452]
Review	Karouzou et al., 2007, Insect Biochem. Mol. Biol. 37(8): 754--760 Drosophila cuticular proteins with the R&R Consensus: annotation and classification with a new tool for discriminating RR-1 and RR-2 sequences. [FBrf0200175]
Personal communication to FlyBase	Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] Willis, 2007.1.3, Drosophila genes that have the R&R consensus. Drosophila genes that have the R&R consensus. [FBrf0199281] Bayraktaroglu, 2000.11.2, Current list of possibly CG-able known genes. Current list of possibly CG-able known genes. [FBrf0131225] BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. (Computer file) Berkeley Drosophila Genome Project. (Computer file) [FBrf0125078]
FlyBase analysis	FlyBase, 1996-, FlyBase inference based on genome sequence analysis. FlyBase inference based on genome sequence analysis. [FBrf0104946] FlyBase, 1992-, FlyBase curation. FlyBase curation. [FBrf0105495]
Website	Fisher et al., 2012, BDGP insitu homepage BDGP insitu homepage [FBrf0219073]
Curated genome annotation	Ashburner, 1999.11, [Annotations performed at the Celera Jamboreee.] [Annotations performed at the Celera Jamboreee.] [FBrf0126651] FamiliarityBreedsContempt, 1999.11, [Automatic annotations performed at the Celera Jamboreee.] [Automatic annotations performed at the Celera Jamboreee.] [FBrf0126705]