General Information Symbol Dmel\ CG7611Species D. melanogaster Name Annotation symbol CG7611 Feature type protein_coding_gene FlyBase ID FBgn0037094 Gene Model Status Current Stock availability 4 publicly
available Genomic Location Chromosome (arm) 3L Recombination map Cytogenetic map 78D5-78D5 Sequence location 3L:21,516,286..21,521,263 [+]
Genomic Maps
Summary Information Automatically generated summary
See sections below for more information This gene is referred to in FlyBase by the symbol
Dmel\CG7611 (FBgn0037094). It is a protein_coding_gene from
Drosophila melanogaster . Its
molecular function is unknown. The
biological processes in which it is involved are not known.
6 alleles are reported . The
phenotypes of these alleles are annotated with: trichogen cell; mesothoracic tergum. It has
9 annotated transcripts and
9 annotated polypeptides .
Protein features are: CTLH, C-terminal LisH motif; G-protein beta WD-40 repeat; LisH dimerisation motif; WD40 repeat; WD40 repeat, conserved site; WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-18 hour embryonic stages, during late larval stages, at stages throughout the pupal period. Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: larval central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, adult female reproductive system, larval/adult carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, adult central nervous system, larval trachea, adult male reproductive system. Comments on Affy2 ProbeSet: ProbeSet 1623225_s_at completely aligns to an exonic region common to each of the 9 FlyBase-annotated transcript isoforms of CG7611. Gene sequence location is
3L:21516286..21521263 .
User Contributed Data
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FB2013_03
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Detailed Mapping Data
FlyBase Computed Cytological Location
Experimentally Determined Cytological Location
Experimentally Determined Recombination Data
Location Left of (cM) Right of (cM) Notes Gene Model & Products Comments on Gene
Model Gene model reviewed during 5.45
Low-frequency RNA-seq exon junction(s) not annotated.
Annotated transcripts do not represent all supported alternative splices within 5' UTR.
Transcript Data Annotated Transcripts Additional Transcript Data
& Comments Reported size (kB) Comments External Data Crossreferences
Polypeptide Data Annotated
Polypeptides Additional Polypeptide
Data & Comments Reported size (kDa) Comments External Data Linkouts Crossreferences
domains - A database of protein families, domains, and functional sites
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank UniProtKB/Swiss-Prot UniProtKB/TrEMBL Mapped Features Mapped Features have been reorganized, please
see this article for details. Additional mapped features and mutations can
be found on GBrowse or related reports. External Data Linkouts Crossreferences Expression Data Transcript ExpressionComment: maternally deposited
Additional Descriptive Data
Marker for Subcellular Localization CV Term Polypeptide Expression
Additional Descriptive Data
Marker for Subcellular Localization (GO Cellular Component) Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference
FlyAtlas Anatomy Microarray
Linear, scaled to maximum expression level
Tissue
Expression Level
Larval Central Nervous System
525.125
Larval Midgut
1270.9
Larval Hindgut
725.1
Larval Malpighian Tubules
1195.9
Larval Fat Body
988.1
Larval Salivary Gland
606.2
Larval Trachea
452.7
Larval Carcass
688
Adult Head
374.7
Adult Eye
299.675
Adult Brain
373
Adult Thoracic-Abdominal Ganglion
381.4
Adult Crop
579.4
Adult Midgut
1094.6
Adult Hindgut
631.1
Adult Malpighian Tubules
606.3
Adult Fat Body
818.1
Adult Salivary Gland
653.1
Adult Heart
560.05
Adult VirginFemale Spermatheca
1024.3
Adult InseminatedFemale Spermatheca
878.1
Adult Ovary
546.1
Adult Testis
114.1
Adult Male Accessory Gland
457.8
Adult Carcass
605
Expression Level Scale
None
Low
Moderate
High
Very high
Linear, scaled to Moderate expression
Tissue
Expression Level
Larval Central Nervous System
525.125
Larval Midgut
(1270.9)
Larval Hindgut
(725.1)
Larval Malpighian Tubules
(1195.9)
Larval Fat Body
(988.1)
Larval Salivary Gland
(606.2)
Larval Trachea
452.7
Larval Carcass
(688)
Adult Head
374.7
Adult Eye
299.675
Adult Brain
373
Adult Thoracic-Abdominal Ganglion
381.4
Adult Crop
(579.4)
Adult Midgut
(1094.6)
Adult Hindgut
(631.1)
Adult Malpighian Tubules
(606.3)
Adult Fat Body
(818.1)
Adult Salivary Gland
(653.1)
Adult Heart
(560.05)
Adult VirginFemale Spermatheca
(1024.3)
Adult InseminatedFemale Spermatheca
(878.1)
Adult Ovary
(546.1)
Adult Testis
114.1
Adult Male Accessory Gland
457.8
Adult Carcass
(605)
Expression Level Scale
None
Low
Moderate
High
Linear, scaled to High level expression
Tissue
Expression Level
Larval Central Nervous System
525.125
Larval Midgut
(1270.9)
Larval Hindgut
725.1
Larval Malpighian Tubules
(1195.9)
Larval Fat Body
988.1
Larval Salivary Gland
606.2
Larval Trachea
452.7
Larval Carcass
688
Adult Head
374.7
Adult Eye
299.675
Adult Brain
373
Adult Thoracic-Abdominal Ganglion
381.4
Adult Crop
579.4
Adult Midgut
(1094.6)
Adult Hindgut
631.1
Adult Malpighian Tubules
606.3
Adult Fat Body
818.1
Adult Salivary Gland
653.1
Adult Heart
560.05
Adult VirginFemale Spermatheca
1024.3
Adult InseminatedFemale Spermatheca
878.1
Adult Ovary
546.1
Adult Testis
114.1
Adult Male Accessory Gland
457.8
Adult Carcass
605
Expression Level Scale
None
Low
Moderate
High
Very high
Linear, scaled to Very high expression
Tissue
Expression Level
Larval Central Nervous System
525.125
Larval Midgut
1270.9
Larval Hindgut
725.1
Larval Malpighian Tubules
1195.9
Larval Fat Body
988.1
Larval Salivary Gland
606.2
Larval Trachea
452.7
Larval Carcass
688
Adult Head
374.7
Adult Eye
299.675
Adult Brain
373
Adult Thoracic-Abdominal Ganglion
381.4
Adult Crop
579.4
Adult Midgut
1094.6
Adult Hindgut
631.1
Adult Malpighian Tubules
606.3
Adult Fat Body
818.1
Adult Salivary Gland
653.1
Adult Heart
560.05
Adult VirginFemale Spermatheca
1024.3
Adult InseminatedFemale Spermatheca
878.1
Adult Ovary
546.1
Adult Testis
114.1
Adult Male Accessory Gland
457.8
Adult Carcass
605
Expression Level Scale
Very high
log, scaled to maximum expression level
Tissue
Expression Level
Larval Central Nervous System
525.125
Larval Midgut
1270.9
Larval Hindgut
725.1
Larval Malpighian Tubules
1195.9
Larval Fat Body
988.1
Larval Salivary Gland
606.2
Larval Trachea
452.7
Larval Carcass
688
Adult Head
374.7
Adult Eye
299.675
Adult Brain
373
Adult Thoracic-Abdominal Ganglion
381.4
Adult Crop
579.4
Adult Midgut
1094.6
Adult Hindgut
631.1
Adult Malpighian Tubules
606.3
Adult Fat Body
818.1
Adult Salivary Gland
653.1
Adult Heart
560.05
Adult VirginFemale Spermatheca
1024.3
Adult InseminatedFemale Spermatheca
878.1
Adult Ovary
546.1
Adult Testis
114.1
Adult Male Accessory Gland
457.8
Adult Carcass
605
Expression Level Scale
None
Low
Moderate
High
Very high
log, scaled to Moderate expression
Tissue
Expression Level
Larval Central Nervous System
525.125
Larval Midgut
(1270.9)
Larval Hindgut
725.1
Larval Malpighian Tubules
(1195.9)
Larval Fat Body
(988.1)
Larval Salivary Gland
606.2
Larval Trachea
452.7
Larval Carcass
688
Adult Head
374.7
Adult Eye
299.675
Adult Brain
373
Adult Thoracic-Abdominal Ganglion
381.4
Adult Crop
579.4
Adult Midgut
(1094.6)
Adult Hindgut
631.1
Adult Malpighian Tubules
606.3
Adult Fat Body
(818.1)
Adult Salivary Gland
653.1
Adult Heart
560.05
Adult VirginFemale Spermatheca
(1024.3)
Adult InseminatedFemale Spermatheca
(878.1)
Adult Ovary
546.1
Adult Testis
114.1
Adult Male Accessory Gland
457.8
Adult Carcass
605
Expression Level Scale
None
Low
Moderate
High
log, scaled to High level expression
Tissue
Expression Level
Larval Central Nervous System
525.125
Larval Midgut
1270.9
Larval Hindgut
725.1
Larval Malpighian Tubules
1195.9
Larval Fat Body
988.1
Larval Salivary Gland
606.2
Larval Trachea
452.7
Larval Carcass
688
Adult Head
374.7
Adult Eye
299.675
Adult Brain
373
Adult Thoracic-Abdominal Ganglion
381.4
Adult Crop
579.4
Adult Midgut
1094.6
Adult Hindgut
631.1
Adult Malpighian Tubules
606.3
Adult Fat Body
818.1
Adult Salivary Gland
653.1
Adult Heart
560.05
Adult VirginFemale Spermatheca
1024.3
Adult InseminatedFemale Spermatheca
878.1
Adult Ovary
546.1
Adult Testis
114.1
Adult Male Accessory Gland
457.8
Adult Carcass
605
Expression Level Scale
None
Low
Moderate
High
Very high
log, scaled to Very high expression
Tissue
Expression Level
Larval Central Nervous System
525.125
Larval Midgut
1270.9
Larval Hindgut
725.1
Larval Malpighian Tubules
1195.9
Larval Fat Body
988.1
Larval Salivary Gland
606.2
Larval Trachea
452.7
Larval Carcass
688
Adult Head
374.7
Adult Eye
299.675
Adult Brain
373
Adult Thoracic-Abdominal Ganglion
381.4
Adult Crop
579.4
Adult Midgut
1094.6
Adult Hindgut
631.1
Adult Malpighian Tubules
606.3
Adult Fat Body
818.1
Adult Salivary Gland
653.1
Adult Heart
560.05
Adult VirginFemale Spermatheca
1024.3
Adult InseminatedFemale Spermatheca
878.1
Adult Ovary
546.1
Adult Testis
114.1
Adult Male Accessory Gland
457.8
Adult Carcass
605
Expression Level Scale
None
Low
Moderate
High
Very high
Heatmap
Tissue
Expression Level
Larval Central Nervous System
Larval Midgut
Larval Hindgut
Larval Malpighian Tubules
Larval Fat Body
Larval Salivary Gland
Larval Trachea
Larval Carcass
Adult Head
Adult Eye
Adult Brain
Adult Thoracic-Abdominal Ganglion
Adult Crop
Adult Midgut
Adult Hindgut
Adult Malpighian Tubules
Adult Fat Body
Adult Salivary Gland
Adult Heart
Adult VirginFemale Spermatheca
Adult InseminatedFemale Spermatheca
Adult Ovary
Adult Testis
Adult Male Accessory Gland
Adult Carcass
FlyAtlas Organ/Tissue Expression, larval vs. adult
Larval Expression Level
Tissue
Adult Expression Level
NA
Head
374.7
NA
Eye
299.675
NA
Brain
373
525.125
Central Nervous System
NA
NA
Thoracic-Abdominal Ganglion
381.4
NA
Crop
579.4
1270.9
Midgut
1094.6
725.1
Hindgut
631.1
1195.9
Malpighian Tubules
606.3
988.1
Fat Body
818.1
606.2
Salivary Gland
653.1
NA
Heart
560.05
452.7
Trachea
NA
NA
VirginFemale Spermatheca
1024.3
NA
InseminatedFemale Spermatheca
878.1
NA
Ovary
546.1
NA
Testis
114.1
NA
Male Accessory Gland
457.8
688
Carcass
605
modENCODE Anatomy RNA-Seq
Linear, scaled to maximum expression level
Tissue
Expression Level
imaginal disc, larvae L3 wandering
26
central nervous system, larvae L3
28
central nervous system, pupae P8
21
head, virgin 1-day female
19
head, virgin 4-day female
17
head, virgin 20-day female
23
head, mated 1-day female
16
head, mated 4-day female
14
head, mated 20-day female
20
head, mated 1-day male
24
head, mated 4-day male
15
head, mated 20-day male
19
salivary gland, larvae L3 wandering
9
salivary gland, white prepupae
102
digestive system, larvae L3 wandering
77
digestive system, 1-day adult
24
digestive system, 4-day adult
22
digestive system, 20-day adult
31
fat body, larvae L3 wandering
13
fat body, white prepupae
44
fat body, pupae P8
29
carcass, larvae L3 wandering
34
carcass, 1-day adult
20
carcass, 4-day adult
13
carcass, 20-day adult
17
ovary, virgin 4-day female
29
ovary, mated 4-day female
25
testis, mated 4-day male
5
accessory gland, mated 4-day male
7
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Moderate expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
26
central nervous system, larvae L3
(28)
central nervous system, pupae P8
21
head, virgin 1-day female
19
head, virgin 4-day female
17
head, virgin 20-day female
23
head, mated 1-day female
16
head, mated 4-day female
14
head, mated 20-day female
20
head, mated 1-day male
24
head, mated 4-day male
15
head, mated 20-day male
19
salivary gland, larvae L3 wandering
9
salivary gland, white prepupae
(102)
digestive system, larvae L3 wandering
(77)
digestive system, 1-day adult
24
digestive system, 4-day adult
22
digestive system, 20-day adult
(31)
fat body, larvae L3 wandering
13
fat body, white prepupae
(44)
fat body, pupae P8
(29)
carcass, larvae L3 wandering
(34)
carcass, 1-day adult
20
carcass, 4-day adult
13
carcass, 20-day adult
17
ovary, virgin 4-day female
(29)
ovary, mated 4-day female
25
testis, mated 4-day male
5
accessory gland, mated 4-day male
7
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
26
central nervous system, larvae L3
28
central nervous system, pupae P8
21
head, virgin 1-day female
19
head, virgin 4-day female
17
head, virgin 20-day female
23
head, mated 1-day female
16
head, mated 4-day female
14
head, mated 20-day female
20
head, mated 1-day male
24
head, mated 4-day male
15
head, mated 20-day male
19
salivary gland, larvae L3 wandering
9
salivary gland, white prepupae
102
digestive system, larvae L3 wandering
77
digestive system, 1-day adult
24
digestive system, 4-day adult
22
digestive system, 20-day adult
31
fat body, larvae L3 wandering
13
fat body, white prepupae
44
fat body, pupae P8
29
carcass, larvae L3 wandering
34
carcass, 1-day adult
20
carcass, 4-day adult
13
carcass, 20-day adult
17
ovary, virgin 4-day female
29
ovary, mated 4-day female
25
testis, mated 4-day male
5
accessory gland, mated 4-day male
7
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
26
central nervous system, larvae L3
28
central nervous system, pupae P8
21
head, virgin 1-day female
19
head, virgin 4-day female
17
head, virgin 20-day female
23
head, mated 1-day female
16
head, mated 4-day female
14
head, mated 20-day female
20
head, mated 1-day male
24
head, mated 4-day male
15
head, mated 20-day male
19
salivary gland, larvae L3 wandering
9
salivary gland, white prepupae
102
digestive system, larvae L3 wandering
77
digestive system, 1-day adult
24
digestive system, 4-day adult
22
digestive system, 20-day adult
31
fat body, larvae L3 wandering
13
fat body, white prepupae
44
fat body, pupae P8
29
carcass, larvae L3 wandering
34
carcass, 1-day adult
20
carcass, 4-day adult
13
carcass, 20-day adult
17
ovary, virgin 4-day female
29
ovary, mated 4-day female
25
testis, mated 4-day male
5
accessory gland, mated 4-day male
7
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Tissue
Expression Level
imaginal disc, larvae L3 wandering
26
central nervous system, larvae L3
28
central nervous system, pupae P8
21
head, virgin 1-day female
19
head, virgin 4-day female
17
head, virgin 20-day female
23
head, mated 1-day female
16
head, mated 4-day female
14
head, mated 20-day female
20
head, mated 1-day male
24
head, mated 4-day male
15
head, mated 20-day male
19
salivary gland, larvae L3 wandering
9
salivary gland, white prepupae
102
digestive system, larvae L3 wandering
77
digestive system, 1-day adult
24
digestive system, 4-day adult
22
digestive system, 20-day adult
31
fat body, larvae L3 wandering
13
fat body, white prepupae
44
fat body, pupae P8
29
carcass, larvae L3 wandering
34
carcass, 1-day adult
20
carcass, 4-day adult
13
carcass, 20-day adult
17
ovary, virgin 4-day female
29
ovary, mated 4-day female
25
testis, mated 4-day male
5
accessory gland, mated 4-day male
7
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Moderate expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
26
central nervous system, larvae L3
28
central nervous system, pupae P8
21
head, virgin 1-day female
19
head, virgin 4-day female
17
head, virgin 20-day female
23
head, mated 1-day female
16
head, mated 4-day female
14
head, mated 20-day female
20
head, mated 1-day male
24
head, mated 4-day male
15
head, mated 20-day male
19
salivary gland, larvae L3 wandering
9
salivary gland, white prepupae
(102)
digestive system, larvae L3 wandering
(77)
digestive system, 1-day adult
24
digestive system, 4-day adult
22
digestive system, 20-day adult
31
fat body, larvae L3 wandering
13
fat body, white prepupae
(44)
fat body, pupae P8
29
carcass, larvae L3 wandering
(34)
carcass, 1-day adult
20
carcass, 4-day adult
13
carcass, 20-day adult
17
ovary, virgin 4-day female
29
ovary, mated 4-day female
25
testis, mated 4-day male
5
accessory gland, mated 4-day male
7
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
26
central nervous system, larvae L3
28
central nervous system, pupae P8
21
head, virgin 1-day female
19
head, virgin 4-day female
17
head, virgin 20-day female
23
head, mated 1-day female
16
head, mated 4-day female
14
head, mated 20-day female
20
head, mated 1-day male
24
head, mated 4-day male
15
head, mated 20-day male
19
salivary gland, larvae L3 wandering
9
salivary gland, white prepupae
102
digestive system, larvae L3 wandering
77
digestive system, 1-day adult
24
digestive system, 4-day adult
22
digestive system, 20-day adult
31
fat body, larvae L3 wandering
13
fat body, white prepupae
44
fat body, pupae P8
29
carcass, larvae L3 wandering
34
carcass, 1-day adult
20
carcass, 4-day adult
13
carcass, 20-day adult
17
ovary, virgin 4-day female
29
ovary, mated 4-day female
25
testis, mated 4-day male
5
accessory gland, mated 4-day male
7
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
26
central nervous system, larvae L3
28
central nervous system, pupae P8
21
head, virgin 1-day female
19
head, virgin 4-day female
17
head, virgin 20-day female
23
head, mated 1-day female
16
head, mated 4-day female
14
head, mated 20-day female
20
head, mated 1-day male
24
head, mated 4-day male
15
head, mated 20-day male
19
salivary gland, larvae L3 wandering
9
salivary gland, white prepupae
102
digestive system, larvae L3 wandering
77
digestive system, 1-day adult
24
digestive system, 4-day adult
22
digestive system, 20-day adult
31
fat body, larvae L3 wandering
13
fat body, white prepupae
44
fat body, pupae P8
29
carcass, larvae L3 wandering
34
carcass, 1-day adult
20
carcass, 4-day adult
13
carcass, 20-day adult
17
ovary, virgin 4-day female
29
ovary, mated 4-day female
25
testis, mated 4-day male
5
accessory gland, mated 4-day male
7
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Tissue
Expression Level
imaginal disc, larvae L3 wandering
central nervous system, larvae L3
central nervous system, pupae P8
head, virgin 1-day female
head, virgin 4-day female
head, virgin 20-day female
head, mated 1-day female
head, mated 4-day female
head, mated 20-day female
head, mated 1-day male
head, mated 4-day male
head, mated 20-day male
salivary gland, larvae L3 wandering
salivary gland, white prepupae
digestive system, larvae L3 wandering
digestive system, 1-day adult
digestive system, 4-day adult
digestive system, 20-day adult
fat body, larvae L3 wandering
fat body, white prepupae
fat body, pupae P8
carcass, larvae L3 wandering
carcass, 1-day adult
carcass, 4-day adult
carcass, 20-day adult
ovary, virgin 4-day female
ovary, mated 4-day female
testis, mated 4-day male
accessory gland, mated 4-day male
modENCODE Development RNA-Seq
Linear, scaled to maximum expression level
Developmental Stage
Expression Level
embryo 00-02hr
55
embryo 02-04hr
95
embryo 04-06hr
110
embryo 06-08hr
104
embryo 08-10hr
89
embryo 10-12hr
79
embryo 12-14hr
77
embryo 14-16hr
107
embryo 16-18hr
68
embryo 18-20hr
48
embryo 20-22hr
40
embryo 22-24hr
36
larva L1
13
larva L2
14
larva L3 12hr old
14
larva L3 puffstage 1-2
29
larva L3 puffstage 3-6
60
larva L3 puffstage 7-9
89
white prepupae new
111
white prepupae 12hr
110
white prepupae 24hr
69
pupae 2d postWPP
72
pupae 3d postWPP
32
pupae 4d postWPP
41
adult male 01day
38
adult male 05day
29
adult male 30day
26
adult female 01day
51
adult female 05day
39
adult female 30day
42
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Moderate expression
Developmental Stage
Expression Level
embryo 00-02hr
(55)
embryo 02-04hr
(95)
embryo 04-06hr
(110)
embryo 06-08hr
(104)
embryo 08-10hr
(89)
embryo 10-12hr
(79)
embryo 12-14hr
(77)
embryo 14-16hr
(107)
embryo 16-18hr
(68)
embryo 18-20hr
(48)
embryo 20-22hr
(40)
embryo 22-24hr
(36)
larva L1
13
larva L2
14
larva L3 12hr old
14
larva L3 puffstage 1-2
(29)
larva L3 puffstage 3-6
(60)
larva L3 puffstage 7-9
(89)
white prepupae new
(111)
white prepupae 12hr
(110)
white prepupae 24hr
(69)
pupae 2d postWPP
(72)
pupae 3d postWPP
(32)
pupae 4d postWPP
(41)
adult male 01day
(38)
adult male 05day
(29)
adult male 30day
26
adult female 01day
(51)
adult female 05day
(39)
adult female 30day
(42)
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Developmental Stage
Expression Level
embryo 00-02hr
55
embryo 02-04hr
95
embryo 04-06hr
(110)
embryo 06-08hr
104
embryo 08-10hr
89
embryo 10-12hr
79
embryo 12-14hr
77
embryo 14-16hr
107
embryo 16-18hr
68
embryo 18-20hr
48
embryo 20-22hr
40
embryo 22-24hr
36
larva L1
13
larva L2
14
larva L3 12hr old
14
larva L3 puffstage 1-2
29
larva L3 puffstage 3-6
60
larva L3 puffstage 7-9
89
white prepupae new
(111)
white prepupae 12hr
(110)
white prepupae 24hr
69
pupae 2d postWPP
72
pupae 3d postWPP
32
pupae 4d postWPP
41
adult male 01day
38
adult male 05day
29
adult male 30day
26
adult female 01day
51
adult female 05day
39
adult female 30day
42
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Developmental Stage
Expression Level
embryo 00-02hr
55
embryo 02-04hr
95
embryo 04-06hr
110
embryo 06-08hr
104
embryo 08-10hr
89
embryo 10-12hr
79
embryo 12-14hr
77
embryo 14-16hr
107
embryo 16-18hr
68
embryo 18-20hr
48
embryo 20-22hr
40
embryo 22-24hr
36
larva L1
13
larva L2
14
larva L3 12hr old
14
larva L3 puffstage 1-2
29
larva L3 puffstage 3-6
60
larva L3 puffstage 7-9
89
white prepupae new
111
white prepupae 12hr
110
white prepupae 24hr
69
pupae 2d postWPP
72
pupae 3d postWPP
32
pupae 4d postWPP
41
adult male 01day
38
adult male 05day
29
adult male 30day
26
adult female 01day
51
adult female 05day
39
adult female 30day
42
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Developmental Stage
Expression Level
embryo 00-02hr
55
embryo 02-04hr
95
embryo 04-06hr
110
embryo 06-08hr
104
embryo 08-10hr
89
embryo 10-12hr
79
embryo 12-14hr
77
embryo 14-16hr
107
embryo 16-18hr
68
embryo 18-20hr
48
embryo 20-22hr
40
embryo 22-24hr
36
larva L1
13
larva L2
14
larva L3 12hr old
14
larva L3 puffstage 1-2
29
larva L3 puffstage 3-6
60
larva L3 puffstage 7-9
89
white prepupae new
111
white prepupae 12hr
110
white prepupae 24hr
69
pupae 2d postWPP
72
pupae 3d postWPP
32
pupae 4d postWPP
41
adult male 01day
38
adult male 05day
29
adult male 30day
26
adult female 01day
51
adult female 05day
39
adult female 30day
42
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Moderate expression
Developmental Stage
Expression Level
embryo 00-02hr
(55)
embryo 02-04hr
(95)
embryo 04-06hr
(110)
embryo 06-08hr
(104)
embryo 08-10hr
(89)
embryo 10-12hr
(79)
embryo 12-14hr
(77)
embryo 14-16hr
(107)
embryo 16-18hr
(68)
embryo 18-20hr
(48)
embryo 20-22hr
(40)
embryo 22-24hr
(36)
larva L1
13
larva L2
14
larva L3 12hr old
14
larva L3 puffstage 1-2
29
larva L3 puffstage 3-6
(60)
larva L3 puffstage 7-9
(89)
white prepupae new
(111)
white prepupae 12hr
(110)
white prepupae 24hr
(69)
pupae 2d postWPP
(72)
pupae 3d postWPP
32
pupae 4d postWPP
(41)
adult male 01day
(38)
adult male 05day
29
adult male 30day
26
adult female 01day
(51)
adult female 05day
(39)
adult female 30day
(42)
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Developmental Stage
Expression Level
embryo 00-02hr
55
embryo 02-04hr
95
embryo 04-06hr
110
embryo 06-08hr
104
embryo 08-10hr
89
embryo 10-12hr
79
embryo 12-14hr
77
embryo 14-16hr
107
embryo 16-18hr
68
embryo 18-20hr
48
embryo 20-22hr
40
embryo 22-24hr
36
larva L1
13
larva L2
14
larva L3 12hr old
14
larva L3 puffstage 1-2
29
larva L3 puffstage 3-6
60
larva L3 puffstage 7-9
89
white prepupae new
111
white prepupae 12hr
110
white prepupae 24hr
69
pupae 2d postWPP
72
pupae 3d postWPP
32
pupae 4d postWPP
41
adult male 01day
38
adult male 05day
29
adult male 30day
26
adult female 01day
51
adult female 05day
39
adult female 30day
42
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Developmental Stage
Expression Level
embryo 00-02hr
55
embryo 02-04hr
95
embryo 04-06hr
110
embryo 06-08hr
104
embryo 08-10hr
89
embryo 10-12hr
79
embryo 12-14hr
77
embryo 14-16hr
107
embryo 16-18hr
68
embryo 18-20hr
48
embryo 20-22hr
40
embryo 22-24hr
36
larva L1
13
larva L2
14
larva L3 12hr old
14
larva L3 puffstage 1-2
29
larva L3 puffstage 3-6
60
larva L3 puffstage 7-9
89
white prepupae new
111
white prepupae 12hr
110
white prepupae 24hr
69
pupae 2d postWPP
72
pupae 3d postWPP
32
pupae 4d postWPP
41
adult male 01day
38
adult male 05day
29
adult male 30day
26
adult female 01day
51
adult female 05day
39
adult female 30day
42
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Developmental Stage
Expression Level
embryo 00-02hr
embryo 02-04hr
embryo 04-06hr
embryo 06-08hr
embryo 08-10hr
embryo 10-12hr
embryo 12-14hr
embryo 14-16hr
embryo 16-18hr
embryo 18-20hr
embryo 20-22hr
embryo 22-24hr
larva L1
larva L2
larva L3 12hr old
larva L3 puffstage 1-2
larva L3 puffstage 3-6
larva L3 puffstage 7-9
white prepupae new
white prepupae 12hr
white prepupae 24hr
pupae 2d postWPP
pupae 3d postWPP
pupae 4d postWPP
adult male 01day
adult male 05day
adult male 30day
adult female 01day
adult female 05day
adult female 30day
modENCODE Cell Lines RNA-Seq
Linear, scaled to maximum expression level
Cell Line
Expression Level
Schneider line 2 S2R+
32
Schneider line 2 Sg4
13
embryonic 1182-4H
26
embryonic GM2
32
embryonic Kc167
14
embryonic S1
36
embryonic S3
11
leg disc CME L1
15
wing disc CME-W2
16
wing disc ML-DmD8
10
wing disc ML-DmD9
30
wing disc ML-DmD16-c3
15
wing disc ML-DmD21
15
wing disc ML-DmD32
13
haltere disc ML-DmD17-c3
28
eye-antennal disc ML-DmD11
19
antennal disc ML-DmD20-c5
10
mixed discs ML-DmD4-c1
16
CNS ML-DmBG1-c1
22
CNS ML-DmBG2-c2
24
tumorous blood cells mbn2
23
ovary fGS/OSS
42
ovary OSC
19
ovary OSS
11
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to Moderate expression
Cell Line
Expression Level
Schneider line 2 S2R+
(32)
Schneider line 2 Sg4
13
embryonic 1182-4H
26
embryonic GM2
(32)
embryonic Kc167
14
embryonic S1
(36)
embryonic S3
11
leg disc CME L1
15
wing disc CME-W2
16
wing disc ML-DmD8
10
wing disc ML-DmD9
(30)
wing disc ML-DmD16-c3
15
wing disc ML-DmD21
15
wing disc ML-DmD32
13
haltere disc ML-DmD17-c3
(28)
eye-antennal disc ML-DmD11
19
antennal disc ML-DmD20-c5
10
mixed discs ML-DmD4-c1
16
CNS ML-DmBG1-c1
22
CNS ML-DmBG2-c2
24
tumorous blood cells mbn2
23
ovary fGS/OSS
(42)
ovary OSC
19
ovary OSS
11
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Cell Line
Expression Level
Schneider line 2 S2R+
32
Schneider line 2 Sg4
13
embryonic 1182-4H
26
embryonic GM2
32
embryonic Kc167
14
embryonic S1
36
embryonic S3
11
leg disc CME L1
15
wing disc CME-W2
16
wing disc ML-DmD8
10
wing disc ML-DmD9
30
wing disc ML-DmD16-c3
15
wing disc ML-DmD21
15
wing disc ML-DmD32
13
haltere disc ML-DmD17-c3
28
eye-antennal disc ML-DmD11
19
antennal disc ML-DmD20-c5
10
mixed discs ML-DmD4-c1
16
CNS ML-DmBG1-c1
22
CNS ML-DmBG2-c2
24
tumorous blood cells mbn2
23
ovary fGS/OSS
42
ovary OSC
19
ovary OSS
11
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Cell Line
Expression Level
Schneider line 2 S2R+
32
Schneider line 2 Sg4
13
embryonic 1182-4H
26
embryonic GM2
32
embryonic Kc167
14
embryonic S1
36
embryonic S3
11
leg disc CME L1
15
wing disc CME-W2
16
wing disc ML-DmD8
10
wing disc ML-DmD9
30
wing disc ML-DmD16-c3
15
wing disc ML-DmD21
15
wing disc ML-DmD32
13
haltere disc ML-DmD17-c3
28
eye-antennal disc ML-DmD11
19
antennal disc ML-DmD20-c5
10
mixed discs ML-DmD4-c1
16
CNS ML-DmBG1-c1
22
CNS ML-DmBG2-c2
24
tumorous blood cells mbn2
23
ovary fGS/OSS
42
ovary OSC
19
ovary OSS
11
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Cell Line
Expression Level
Schneider line 2 S2R+
32
Schneider line 2 Sg4
13
embryonic 1182-4H
26
embryonic GM2
32
embryonic Kc167
14
embryonic S1
36
embryonic S3
11
leg disc CME L1
15
wing disc CME-W2
16
wing disc ML-DmD8
10
wing disc ML-DmD9
30
wing disc ML-DmD16-c3
15
wing disc ML-DmD21
15
wing disc ML-DmD32
13
haltere disc ML-DmD17-c3
28
eye-antennal disc ML-DmD11
19
antennal disc ML-DmD20-c5
10
mixed discs ML-DmD4-c1
16
CNS ML-DmBG1-c1
22
CNS ML-DmBG2-c2
24
tumorous blood cells mbn2
23
ovary fGS/OSS
42
ovary OSC
19
ovary OSS
11
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
log, scaled to Moderate expression
Cell Line
Expression Level
Schneider line 2 S2R+
32
Schneider line 2 Sg4
13
embryonic 1182-4H
26
embryonic GM2
32
embryonic Kc167
14
embryonic S1
(36)
embryonic S3
11
leg disc CME L1
15
wing disc CME-W2
16
wing disc ML-DmD8
10
wing disc ML-DmD9
30
wing disc ML-DmD16-c3
15
wing disc ML-DmD21
15
wing disc ML-DmD32
13
haltere disc ML-DmD17-c3
28
eye-antennal disc ML-DmD11
19
antennal disc ML-DmD20-c5
10
mixed discs ML-DmD4-c1
16
CNS ML-DmBG1-c1
22
CNS ML-DmBG2-c2
24
tumorous blood cells mbn2
23
ovary fGS/OSS
(42)
ovary OSC
19
ovary OSS
11
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Cell Line
Expression Level
Schneider line 2 S2R+
32
Schneider line 2 Sg4
13
embryonic 1182-4H
26
embryonic GM2
32
embryonic Kc167
14
embryonic S1
36
embryonic S3
11
leg disc CME L1
15
wing disc CME-W2
16
wing disc ML-DmD8
10
wing disc ML-DmD9
30
wing disc ML-DmD16-c3
15
wing disc ML-DmD21
15
wing disc ML-DmD32
13
haltere disc ML-DmD17-c3
28
eye-antennal disc ML-DmD11
19
antennal disc ML-DmD20-c5
10
mixed discs ML-DmD4-c1
16
CNS ML-DmBG1-c1
22
CNS ML-DmBG2-c2
24
tumorous blood cells mbn2
23
ovary fGS/OSS
42
ovary OSC
19
ovary OSS
11
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Cell Line
Expression Level
Schneider line 2 S2R+
32
Schneider line 2 Sg4
13
embryonic 1182-4H
26
embryonic GM2
32
embryonic Kc167
14
embryonic S1
36
embryonic S3
11
leg disc CME L1
15
wing disc CME-W2
16
wing disc ML-DmD8
10
wing disc ML-DmD9
30
wing disc ML-DmD16-c3
15
wing disc ML-DmD21
15
wing disc ML-DmD32
13
haltere disc ML-DmD17-c3
28
eye-antennal disc ML-DmD11
19
antennal disc ML-DmD20-c5
10
mixed discs ML-DmD4-c1
16
CNS ML-DmBG1-c1
22
CNS ML-DmBG2-c2
24
tumorous blood cells mbn2
23
ovary fGS/OSS
42
ovary OSC
19
ovary OSS
11
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Cell Line
Expression Level
Schneider line 2 S2R+
Schneider line 2 Sg4
embryonic 1182-4H
embryonic GM2
embryonic Kc167
embryonic S1
embryonic S3
leg disc CME L1
wing disc CME-W2
wing disc ML-DmD8
wing disc ML-DmD9
wing disc ML-DmD16-c3
wing disc ML-DmD21
wing disc ML-DmD32
haltere disc ML-DmD17-c3
eye-antennal disc ML-DmD11
antennal disc ML-DmD20-c5
mixed discs ML-DmD4-c1
CNS ML-DmBG1-c1
CNS ML-DmBG2-c2
tumorous blood cells mbn2
ovary fGS/OSS
ovary OSC
ovary OSS
modENCODE Treatments RNA-Seq
Linear, scaled to maximum expression level
Treatment
Expression Level
extended cold, 4-day adult
30
cold shock, 4-day adult
25
heat shock, 4-day adult
18
Cadmium 50 mM 6 hrs, larvae L3
13
Cadmium 50 mM 12 hrs, larvae L3
23
Cadmium 50 mM 48 hrs, 4-day adult
15
Cadmium 100 mM 48 hrs, 4-day adult
22
Copper 0.5 mM 12 hrs, larvae L3
15
Copper 15 mM 48 hrs, 4-day adult
11
Zinc 5 mM 12 hrs, larvae L3
16
Zinc 4.5 mM 48 hrs, 4-day adult
13
Ethanol 2.5% 3 hrs, larvae L3
32
Ethanol 5% 3 hrs, larvae L3
15
Ethanol 10% 3 hrs, larvae L3
12
Caffeine 1.5 mg/ml 4 hrs, larvae L3
20
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
23
Caffeine 25 mg/ml 48 hrs, 4-day adult
21
Paraquat 5 mM 48 hrs, 4-day adult
25
Paraquat 10 mM 48 hrs, 4-day adult
29
Rotenone 2 μg 12 hrs, larvae L3
14
Rotenone 8 μg 12 hrs, larvae L3
12
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to Moderate expression
Treatment
Expression Level
extended cold, 4-day adult
(30)
cold shock, 4-day adult
25
heat shock, 4-day adult
18
Cadmium 50 mM 6 hrs, larvae L3
13
Cadmium 50 mM 12 hrs, larvae L3
23
Cadmium 50 mM 48 hrs, 4-day adult
15
Cadmium 100 mM 48 hrs, 4-day adult
22
Copper 0.5 mM 12 hrs, larvae L3
15
Copper 15 mM 48 hrs, 4-day adult
11
Zinc 5 mM 12 hrs, larvae L3
16
Zinc 4.5 mM 48 hrs, 4-day adult
13
Ethanol 2.5% 3 hrs, larvae L3
(32)
Ethanol 5% 3 hrs, larvae L3
15
Ethanol 10% 3 hrs, larvae L3
12
Caffeine 1.5 mg/ml 4 hrs, larvae L3
20
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
23
Caffeine 25 mg/ml 48 hrs, 4-day adult
21
Paraquat 5 mM 48 hrs, 4-day adult
25
Paraquat 10 mM 48 hrs, 4-day adult
(29)
Rotenone 2 μg 12 hrs, larvae L3
14
Rotenone 8 μg 12 hrs, larvae L3
12
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Treatment
Expression Level
extended cold, 4-day adult
30
cold shock, 4-day adult
25
heat shock, 4-day adult
18
Cadmium 50 mM 6 hrs, larvae L3
13
Cadmium 50 mM 12 hrs, larvae L3
23
Cadmium 50 mM 48 hrs, 4-day adult
15
Cadmium 100 mM 48 hrs, 4-day adult
22
Copper 0.5 mM 12 hrs, larvae L3
15
Copper 15 mM 48 hrs, 4-day adult
11
Zinc 5 mM 12 hrs, larvae L3
16
Zinc 4.5 mM 48 hrs, 4-day adult
13
Ethanol 2.5% 3 hrs, larvae L3
32
Ethanol 5% 3 hrs, larvae L3
15
Ethanol 10% 3 hrs, larvae L3
12
Caffeine 1.5 mg/ml 4 hrs, larvae L3
20
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
23
Caffeine 25 mg/ml 48 hrs, 4-day adult
21
Paraquat 5 mM 48 hrs, 4-day adult
25
Paraquat 10 mM 48 hrs, 4-day adult
29
Rotenone 2 μg 12 hrs, larvae L3
14
Rotenone 8 μg 12 hrs, larvae L3
12
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Treatment
Expression Level
extended cold, 4-day adult
30
cold shock, 4-day adult
25
heat shock, 4-day adult
18
Cadmium 50 mM 6 hrs, larvae L3
13
Cadmium 50 mM 12 hrs, larvae L3
23
Cadmium 50 mM 48 hrs, 4-day adult
15
Cadmium 100 mM 48 hrs, 4-day adult
22
Copper 0.5 mM 12 hrs, larvae L3
15
Copper 15 mM 48 hrs, 4-day adult
11
Zinc 5 mM 12 hrs, larvae L3
16
Zinc 4.5 mM 48 hrs, 4-day adult
13
Ethanol 2.5% 3 hrs, larvae L3
32
Ethanol 5% 3 hrs, larvae L3
15
Ethanol 10% 3 hrs, larvae L3
12
Caffeine 1.5 mg/ml 4 hrs, larvae L3
20
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
23
Caffeine 25 mg/ml 48 hrs, 4-day adult
21
Paraquat 5 mM 48 hrs, 4-day adult
25
Paraquat 10 mM 48 hrs, 4-day adult
29
Rotenone 2 μg 12 hrs, larvae L3
14
Rotenone 8 μg 12 hrs, larvae L3
12
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Treatment
Expression Level
extended cold, 4-day adult
30
cold shock, 4-day adult
25
heat shock, 4-day adult
18
Cadmium 50 mM 6 hrs, larvae L3
13
Cadmium 50 mM 12 hrs, larvae L3
23
Cadmium 50 mM 48 hrs, 4-day adult
15
Cadmium 100 mM 48 hrs, 4-day adult
22
Copper 0.5 mM 12 hrs, larvae L3
15
Copper 15 mM 48 hrs, 4-day adult
11
Zinc 5 mM 12 hrs, larvae L3
16
Zinc 4.5 mM 48 hrs, 4-day adult
13
Ethanol 2.5% 3 hrs, larvae L3
32
Ethanol 5% 3 hrs, larvae L3
15
Ethanol 10% 3 hrs, larvae L3
12
Caffeine 1.5 mg/ml 4 hrs, larvae L3
20
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
23
Caffeine 25 mg/ml 48 hrs, 4-day adult
21
Paraquat 5 mM 48 hrs, 4-day adult
25
Paraquat 10 mM 48 hrs, 4-day adult
29
Rotenone 2 μg 12 hrs, larvae L3
14
Rotenone 8 μg 12 hrs, larvae L3
12
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to Moderate expression
Treatment
Expression Level
extended cold, 4-day adult
30
cold shock, 4-day adult
25
heat shock, 4-day adult
18
Cadmium 50 mM 6 hrs, larvae L3
13
Cadmium 50 mM 12 hrs, larvae L3
23
Cadmium 50 mM 48 hrs, 4-day adult
15
Cadmium 100 mM 48 hrs, 4-day adult
22
Copper 0.5 mM 12 hrs, larvae L3
15
Copper 15 mM 48 hrs, 4-day adult
11
Zinc 5 mM 12 hrs, larvae L3
16
Zinc 4.5 mM 48 hrs, 4-day adult
13
Ethanol 2.5% 3 hrs, larvae L3
32
Ethanol 5% 3 hrs, larvae L3
15
Ethanol 10% 3 hrs, larvae L3
12
Caffeine 1.5 mg/ml 4 hrs, larvae L3
20
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
23
Caffeine 25 mg/ml 48 hrs, 4-day adult
21
Paraquat 5 mM 48 hrs, 4-day adult
25
Paraquat 10 mM 48 hrs, 4-day adult
29
Rotenone 2 μg 12 hrs, larvae L3
14
Rotenone 8 μg 12 hrs, larvae L3
12
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Treatment
Expression Level
extended cold, 4-day adult
30
cold shock, 4-day adult
25
heat shock, 4-day adult
18
Cadmium 50 mM 6 hrs, larvae L3
13
Cadmium 50 mM 12 hrs, larvae L3
23
Cadmium 50 mM 48 hrs, 4-day adult
15
Cadmium 100 mM 48 hrs, 4-day adult
22
Copper 0.5 mM 12 hrs, larvae L3
15
Copper 15 mM 48 hrs, 4-day adult
11
Zinc 5 mM 12 hrs, larvae L3
16
Zinc 4.5 mM 48 hrs, 4-day adult
13
Ethanol 2.5% 3 hrs, larvae L3
32
Ethanol 5% 3 hrs, larvae L3
15
Ethanol 10% 3 hrs, larvae L3
12
Caffeine 1.5 mg/ml 4 hrs, larvae L3
20
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
23
Caffeine 25 mg/ml 48 hrs, 4-day adult
21
Paraquat 5 mM 48 hrs, 4-day adult
25
Paraquat 10 mM 48 hrs, 4-day adult
29
Rotenone 2 μg 12 hrs, larvae L3
14
Rotenone 8 μg 12 hrs, larvae L3
12
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Treatment
Expression Level
extended cold, 4-day adult
30
cold shock, 4-day adult
25
heat shock, 4-day adult
18
Cadmium 50 mM 6 hrs, larvae L3
13
Cadmium 50 mM 12 hrs, larvae L3
23
Cadmium 50 mM 48 hrs, 4-day adult
15
Cadmium 100 mM 48 hrs, 4-day adult
22
Copper 0.5 mM 12 hrs, larvae L3
15
Copper 15 mM 48 hrs, 4-day adult
11
Zinc 5 mM 12 hrs, larvae L3
16
Zinc 4.5 mM 48 hrs, 4-day adult
13
Ethanol 2.5% 3 hrs, larvae L3
32
Ethanol 5% 3 hrs, larvae L3
15
Ethanol 10% 3 hrs, larvae L3
12
Caffeine 1.5 mg/ml 4 hrs, larvae L3
20
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
23
Caffeine 25 mg/ml 48 hrs, 4-day adult
21
Paraquat 5 mM 48 hrs, 4-day adult
25
Paraquat 10 mM 48 hrs, 4-day adult
29
Rotenone 2 μg 12 hrs, larvae L3
14
Rotenone 8 μg 12 hrs, larvae L3
12
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Treatment
Expression Level
extended cold, 4-day adult
cold shock, 4-day adult
heat shock, 4-day adult
Cadmium 50 mM 6 hrs, larvae L3
Cadmium 50 mM 12 hrs, larvae L3
Cadmium 50 mM 48 hrs, 4-day adult
Cadmium 100 mM 48 hrs, 4-day adult
Copper 0.5 mM 12 hrs, larvae L3
Copper 15 mM 48 hrs, 4-day adult
Zinc 5 mM 12 hrs, larvae L3
Zinc 4.5 mM 48 hrs, 4-day adult
Ethanol 2.5% 3 hrs, larvae L3
Ethanol 5% 3 hrs, larvae L3
Ethanol 10% 3 hrs, larvae L3
Caffeine 1.5 mg/ml 4 hrs, larvae L3
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
Caffeine 25 mg/ml 48 hrs, 4-day adult
Paraquat 5 mM 48 hrs, 4-day adult
Paraquat 10 mM 48 hrs, 4-day adult
Rotenone 2 μg 12 hrs, larvae L3
Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
A cluster of genes with similar mRNA expression dynamics across development.
External Data & Images
Linkouts
- Cell culture data for RNAi and other high-throughput technologies
- Adult expression by tissue, using Affymetrix Dros2 array
Alleles & Phenotypes Summary of Allele Phenotypes Classical Alleles ( 3 ) For All Classical Alleles Show Alleles Carried on Transgenic Constructs
( 3 ) For All Alleles Carried on Transgenic
Constructs Show Aneuploid Aberrations Transgenic Constructs & Insertions
Transgenic Constructs Insertions insertion of mobile activating element
Gene Ontology: Function, Process
& Cellular Component ( 1 unique term )There is no information supporting a
biological process or molecular function term for this gene.
(Based on a review of available data before: 2006)
Terms Based on
Experimental Evidence ( 0 terms ) Terms Based on Predictions or
Assertions ( 1 term ) Molecular Function ( 0 terms) Biological Process ( 0 terms) Cellular Component inferred from sequence or structural similarity with
UniProtKB:Q9H7D7
(assigned by UniProtKB)
Sequence Ontology: Class of Gene Interactions & Pathways
Summary of Physical Interactions
protein-protein anti tag coimmunoprecipitation, peptide massfingerprinting, experimental knowledge based
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting, experimental knowledge based
anti tag coimmunoprecipitation, peptide massfingerprinting, experimental knowledge based
experimental knowledge based
anti tag coimmunoprecipitation, peptide massfingerprinting
Summary of Genetic Interactions Interacts with Please look at the allele data
for full details of the genetic interactions
External Data Linkouts
- A database of protein and genetic interactions
- DPiM, Drosophila Protein interaction Map
- A comprehensive database of gene and protein interactions.
Protein-protein interactions (PPI) from both known and predicted PPI data sets.
- A protein-protein and protein-miRNA interaction database with multi-layered structure and multiple confidence scores.
Orthologs
OrthoDB Orthologs (43)
- based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
OrthoDB orthology group searches
Drosophila inclusive ortholog search
Dipteran inclusive ortholog search
Insect inclusive ortholog search
Arthropod inclusive ortholog search
Metazoa inclusive ortholog search
Orthologs in Drosophila Species
(EOG6FR1B6 )
Drosophila melanogaster
fruit fly
Drosophila pseudoobscura pseudoobscura
Y
Orthologs in non-Drosophila Dipterans
(EOG6QNN4D )
Aedes aegypti
Yellow fever mosquito
Anopheles gambiae
Malaria mosquito
Culex quinquefasciatus
Southern house mosquito
Orthologs in non-Dipteran Insects
(EOG6KH1Q3 )
Apis mellifera
Western honey bee
Amel\GB48563
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG007465
Acromyrmex echinatior
Panamanian leafcutter ant
Aech\AECH14640
Atta cephalotes
Leafcutter ant
Acep\ACEP24035
Camponotus floridanus
Florida carpenter ant
Cflo\CFLO20424
Harpegnathos saltator
Jerdons jumping ant
Hsal\HSAL16484
Linepithema humile
Argentine ant
Lhum\LH19181
Pogonomyrmex barbatus
Red harvester ant
Pbar\PB18430
Solenopsis invicta
Red fire ant
Sinv\SINV22704
Solenopsis invicta
Red fire ant
Sinv\SINV22709
Acyrthosiphon pisum
Pea aphid
Pediculus humanus
Human body louse
Tribolium castaneum
Red flour beetle
Orthologs in non-Insect Arthropods
(EOG6Z613P )
Ixodes scapularis
Deer tick
Orthologs in non-Arthropod Metazoa
(EOG6KT2BZ )
Caenorhabditis elegans
Nematode
Strongylocentrotus purpuratus
Purple sea urchin
Strongylocentrotus purpuratus
Purple sea urchin
Strongylocentrotus purpuratus
Purple sea urchin
Xenopus tropicalis
Western clawed frog
Gallus gallus
Domestic chicken
Rattus norvegicus
Norway rat
Human Orthologs (1)AAA Orthologs (11)
based on analysis using Dmel annotation version 4.3
Drosophila pseudoobscura pseudoobscura
Stocks & Reagents Stocks Listed in FlyBase ( 4 )Bloomington VDRC Genomic Clones ( 2 )Please Note FlyBase no
longer curates genomic clone accessions so this list
may not be complete
cDNA Clones ( 656 )Please Note This section lists
cDNAs and ESTs that fall within the genomic extent
of the gene model, which may include cDNAs and ESTs
of genes within introns, or of overlapping genes.
Please see
GBrowse for alignment of the cDNAs and ESTs
to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones Other clones cDNA Clones, End Sequenced
(ESTs) BDGP DGC clones Other clones RNAi & Array Information Linkouts
- Results from RNAi screens.
- GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents
Antibody Information
Other Information Discoverer Etymology Identification Relationship to Other Genes Source for database identity of Source for database merge of Additional comments Other Comments External Crossreferences & Linkouts
Sequence Crossreferences
- A searchable database of RefSeq genes.
Other Crossreferences
domains - A database of protein families, domains, and functional sites
- Patterns of gene expression in Drosophila embryogenesis
Linkouts
- A database of protein and genetic interactions
- DPiM, Drosophila Protein interaction Map
- A comprehensive database of gene and protein interactions.
- Results from RNAi screens.
- Cell culture data for RNAi and other high-throughput technologies
- Adult expression by tissue, using Affymetrix Dros2 array
- Integrated genomics database for Drosophila, Anopheles, and C.elegans
- GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents
Protein-protein interactions (PPI) from both known and predicted PPI data sets.
- Data generated by the modENCODE project.
- A protein-protein and protein-miRNA interaction database with multi-layered structure and multiple confidence scores.
Synonyms & Secondary IDs
( 2 )Reported As Symbol Synonym CG7611
(
UniProtKB Project Members, 2007.3.20 ,
Przewloka et al., 2007 ,
Finan et al., 2011 ,
Higa et al., 2006 ,
Keleman et al., 2009.8.5 ,
Japanese National Institute of Genetics, 2012.5.21 )
Name Synonym Secondary FlyBase
IDs References ( 23 )Generate a list of List References by type
Recent research papers ( 1 )
Finan et al., 2011, Proc. Natl. Acad. Sci. U.S.A. 108(14): 5566--5571From the Cover: Proteomics approach to study the functions of Drosophila myosin VI through identification of multiple cargo-binding proteins. [FBrf0213355]