General Information Symbol Dmel\ CG11306Species D. melanogaster Name Annotation symbol CG11306 Feature type protein_coding_gene FlyBase ID FBgn0037108 Gene Model Status Current Stock availability 4 publicly
available Genomic Location Chromosome (arm) 3L Recombination map Cytogenetic map 78E1-78E1 Sequence location 3L:21,618,995..21,621,671 [+]
Genomic Maps
Summary Information Automatically generated summary
See sections below for more information This gene is referred to in FlyBase by the symbol
Dmel\CG11306 (FBgn0037108). It is a protein_coding_gene from
Drosophila melanogaster . Based on sequence similarity, it is predicted to have
molecular function : alpha-1,2-mannosyltransferase activity. There is experimental evidence that it is involved in the
biological process : neurogenesis.
3 alleles are reported . No phenotypic data is available. It has
2 annotated transcripts and
2 annotated polypeptides .
Protein features are: Glycosyl transferase, family 1. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderately high expression. Peak expression observed within 00-18 hour embryonic stages. Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult organs/tissues expressed at moderate or high levels. Expression at high levels in the following post-embryonic organs or tissues: adult eye, larval fat body, larval/adult salivary gland, larval trachea, adult spermathecae, adult male accessory gland. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, adult fat body, adult ovary, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1640824_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG11306. Gene sequence location is
3L:21618995..21621671 .
User Contributed Data
Recent Updates
Description
What does this section display?
This section contains items that were added to this record for each release.
It currently only tracks new links between this FlyBase report and other
FlyBase data classes (e.g. genes, references, stocks) or controlled
vocabulary terms (e.g. GO, anatomy terms).
What does this section not display?
This section does not currently display links that were removed or gene model changes.
Update Feed
Click the icon below to subscribe to this FlyBase record and receive updates automatically through your
feed reader .
FB2013_03
FB2013_02
All updates
Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Experimentally Determined Cytological Location
Experimentally Determined Recombination Data
Location Left of (cM) Right of (cM) Notes Gene Model & Products Comments on Gene
Model Gene model reviewed during 5.46
Low-frequency RNA-Seq exon junction(s) not annotated.
Transcript Data Annotated Transcripts Additional Transcript Data
& Comments Reported size (kB) Comments External Data Crossreferences
Polypeptide Data Annotated
Polypeptides Additional Polypeptide
Data & Comments Reported size (kDa) Comments External Data Linkouts Crossreferences
domains - A database of protein families, domains, and functional sites
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank UniProtKB/Swiss-Prot UniProtKB/TrEMBL Mapped Features Mapped Features have been reorganized, please
see this article for details. Additional mapped features and mutations can
be found on GBrowse or related reports. External Data Linkouts Crossreferences Expression Data Transcript ExpressionComment: maternally deposited
Additional Descriptive Data
Marker for Subcellular Localization CV Term Polypeptide Expression
Additional Descriptive Data
Marker for Subcellular Localization (GO Cellular Component) Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference
FlyAtlas Anatomy Microarray
Linear, scaled to maximum expression level
Tissue
Expression Level
Larval Central Nervous System
376.9
Larval Midgut
411.9
Larval Hindgut
299.2
Larval Malpighian Tubules
463.3
Larval Fat Body
502.6
Larval Salivary Gland
907.9
Larval Trachea
502.775
Larval Carcass
293.625
Adult Head
358.3
Adult Eye
624.3
Adult Brain
363.9
Adult Thoracic-Abdominal Ganglion
380.9
Adult Crop
243.4
Adult Midgut
498.2
Adult Hindgut
261.9
Adult Malpighian Tubules
382
Adult Fat Body
353.6
Adult Salivary Gland
1920.1
Adult Heart
399.4
Adult VirginFemale Spermatheca
532.8
Adult InseminatedFemale Spermatheca
547.3
Adult Ovary
293.6
Adult Testis
94.9
Adult Male Accessory Gland
1106.3
Adult Carcass
242.7
Expression Level Scale
None
Low
Moderate
High
Very high
Linear, scaled to Moderate expression
Tissue
Expression Level
Larval Central Nervous System
376.9
Larval Midgut
411.9
Larval Hindgut
299.2
Larval Malpighian Tubules
463.3
Larval Fat Body
502.6
Larval Salivary Gland
(907.9)
Larval Trachea
502.775
Larval Carcass
293.625
Adult Head
358.3
Adult Eye
(624.3)
Adult Brain
363.9
Adult Thoracic-Abdominal Ganglion
380.9
Adult Crop
243.4
Adult Midgut
498.2
Adult Hindgut
261.9
Adult Malpighian Tubules
382
Adult Fat Body
353.6
Adult Salivary Gland
(1920.1)
Adult Heart
399.4
Adult VirginFemale Spermatheca
532.8
Adult InseminatedFemale Spermatheca
(547.3)
Adult Ovary
293.6
Adult Testis
94.9
Adult Male Accessory Gland
(1106.3)
Adult Carcass
242.7
Expression Level Scale
None
Low
Moderate
High
Linear, scaled to High level expression
Tissue
Expression Level
Larval Central Nervous System
376.9
Larval Midgut
411.9
Larval Hindgut
299.2
Larval Malpighian Tubules
463.3
Larval Fat Body
502.6
Larval Salivary Gland
907.9
Larval Trachea
502.775
Larval Carcass
293.625
Adult Head
358.3
Adult Eye
624.3
Adult Brain
363.9
Adult Thoracic-Abdominal Ganglion
380.9
Adult Crop
243.4
Adult Midgut
498.2
Adult Hindgut
261.9
Adult Malpighian Tubules
382
Adult Fat Body
353.6
Adult Salivary Gland
(1920.1)
Adult Heart
399.4
Adult VirginFemale Spermatheca
532.8
Adult InseminatedFemale Spermatheca
547.3
Adult Ovary
293.6
Adult Testis
94.9
Adult Male Accessory Gland
(1106.3)
Adult Carcass
242.7
Expression Level Scale
None
Low
Moderate
High
Very high
Linear, scaled to Very high expression
Tissue
Expression Level
Larval Central Nervous System
376.9
Larval Midgut
411.9
Larval Hindgut
299.2
Larval Malpighian Tubules
463.3
Larval Fat Body
502.6
Larval Salivary Gland
907.9
Larval Trachea
502.775
Larval Carcass
293.625
Adult Head
358.3
Adult Eye
624.3
Adult Brain
363.9
Adult Thoracic-Abdominal Ganglion
380.9
Adult Crop
243.4
Adult Midgut
498.2
Adult Hindgut
261.9
Adult Malpighian Tubules
382
Adult Fat Body
353.6
Adult Salivary Gland
1920.1
Adult Heart
399.4
Adult VirginFemale Spermatheca
532.8
Adult InseminatedFemale Spermatheca
547.3
Adult Ovary
293.6
Adult Testis
94.9
Adult Male Accessory Gland
1106.3
Adult Carcass
242.7
Expression Level Scale
Very high
log, scaled to maximum expression level
Tissue
Expression Level
Larval Central Nervous System
376.9
Larval Midgut
411.9
Larval Hindgut
299.2
Larval Malpighian Tubules
463.3
Larval Fat Body
502.6
Larval Salivary Gland
907.9
Larval Trachea
502.775
Larval Carcass
293.625
Adult Head
358.3
Adult Eye
624.3
Adult Brain
363.9
Adult Thoracic-Abdominal Ganglion
380.9
Adult Crop
243.4
Adult Midgut
498.2
Adult Hindgut
261.9
Adult Malpighian Tubules
382
Adult Fat Body
353.6
Adult Salivary Gland
1920.1
Adult Heart
399.4
Adult VirginFemale Spermatheca
532.8
Adult InseminatedFemale Spermatheca
547.3
Adult Ovary
293.6
Adult Testis
94.9
Adult Male Accessory Gland
1106.3
Adult Carcass
242.7
Expression Level Scale
None
Low
Moderate
High
Very high
log, scaled to Moderate expression
Tissue
Expression Level
Larval Central Nervous System
376.9
Larval Midgut
411.9
Larval Hindgut
299.2
Larval Malpighian Tubules
463.3
Larval Fat Body
502.6
Larval Salivary Gland
(907.9)
Larval Trachea
502.775
Larval Carcass
293.625
Adult Head
358.3
Adult Eye
624.3
Adult Brain
363.9
Adult Thoracic-Abdominal Ganglion
380.9
Adult Crop
243.4
Adult Midgut
498.2
Adult Hindgut
261.9
Adult Malpighian Tubules
382
Adult Fat Body
353.6
Adult Salivary Gland
(1920.1)
Adult Heart
399.4
Adult VirginFemale Spermatheca
532.8
Adult InseminatedFemale Spermatheca
547.3
Adult Ovary
293.6
Adult Testis
94.9
Adult Male Accessory Gland
(1106.3)
Adult Carcass
242.7
Expression Level Scale
None
Low
Moderate
High
log, scaled to High level expression
Tissue
Expression Level
Larval Central Nervous System
376.9
Larval Midgut
411.9
Larval Hindgut
299.2
Larval Malpighian Tubules
463.3
Larval Fat Body
502.6
Larval Salivary Gland
907.9
Larval Trachea
502.775
Larval Carcass
293.625
Adult Head
358.3
Adult Eye
624.3
Adult Brain
363.9
Adult Thoracic-Abdominal Ganglion
380.9
Adult Crop
243.4
Adult Midgut
498.2
Adult Hindgut
261.9
Adult Malpighian Tubules
382
Adult Fat Body
353.6
Adult Salivary Gland
(1920.1)
Adult Heart
399.4
Adult VirginFemale Spermatheca
532.8
Adult InseminatedFemale Spermatheca
547.3
Adult Ovary
293.6
Adult Testis
94.9
Adult Male Accessory Gland
1106.3
Adult Carcass
242.7
Expression Level Scale
None
Low
Moderate
High
Very high
log, scaled to Very high expression
Tissue
Expression Level
Larval Central Nervous System
376.9
Larval Midgut
411.9
Larval Hindgut
299.2
Larval Malpighian Tubules
463.3
Larval Fat Body
502.6
Larval Salivary Gland
907.9
Larval Trachea
502.775
Larval Carcass
293.625
Adult Head
358.3
Adult Eye
624.3
Adult Brain
363.9
Adult Thoracic-Abdominal Ganglion
380.9
Adult Crop
243.4
Adult Midgut
498.2
Adult Hindgut
261.9
Adult Malpighian Tubules
382
Adult Fat Body
353.6
Adult Salivary Gland
1920.1
Adult Heart
399.4
Adult VirginFemale Spermatheca
532.8
Adult InseminatedFemale Spermatheca
547.3
Adult Ovary
293.6
Adult Testis
94.9
Adult Male Accessory Gland
1106.3
Adult Carcass
242.7
Expression Level Scale
None
Low
Moderate
High
Very high
Heatmap
Tissue
Expression Level
Larval Central Nervous System
Larval Midgut
Larval Hindgut
Larval Malpighian Tubules
Larval Fat Body
Larval Salivary Gland
Larval Trachea
Larval Carcass
Adult Head
Adult Eye
Adult Brain
Adult Thoracic-Abdominal Ganglion
Adult Crop
Adult Midgut
Adult Hindgut
Adult Malpighian Tubules
Adult Fat Body
Adult Salivary Gland
Adult Heart
Adult VirginFemale Spermatheca
Adult InseminatedFemale Spermatheca
Adult Ovary
Adult Testis
Adult Male Accessory Gland
Adult Carcass
FlyAtlas Organ/Tissue Expression, larval vs. adult
Larval Expression Level
Tissue
Adult Expression Level
NA
Head
358.3
NA
Eye
624.3
NA
Brain
363.9
376.9
Central Nervous System
NA
NA
Thoracic-Abdominal Ganglion
380.9
NA
Crop
243.4
411.9
Midgut
498.2
299.2
Hindgut
261.9
463.3
Malpighian Tubules
382
502.6
Fat Body
353.6
907.9
Salivary Gland
1920.1
NA
Heart
399.4
502.775
Trachea
NA
NA
VirginFemale Spermatheca
532.8
NA
InseminatedFemale Spermatheca
547.3
NA
Ovary
293.6
NA
Testis
94.9
NA
Male Accessory Gland
1106.3
293.625
Carcass
242.7
modENCODE Anatomy RNA-Seq
Linear, scaled to maximum expression level
Tissue
Expression Level
imaginal disc, larvae L3 wandering
18
central nervous system, larvae L3
22
central nervous system, pupae P8
32
head, virgin 1-day female
24
head, virgin 4-day female
19
head, virgin 20-day female
29
head, mated 1-day female
13
head, mated 4-day female
19
head, mated 20-day female
21
head, mated 1-day male
28
head, mated 4-day male
30
head, mated 20-day male
37
salivary gland, larvae L3 wandering
12
salivary gland, white prepupae
12
digestive system, larvae L3 wandering
25
digestive system, 1-day adult
25
digestive system, 4-day adult
18
digestive system, 20-day adult
18
fat body, larvae L3 wandering
13
fat body, white prepupae
16
fat body, pupae P8
30
carcass, larvae L3 wandering
19
carcass, 1-day adult
12
carcass, 4-day adult
14
carcass, 20-day adult
15
ovary, virgin 4-day female
28
ovary, mated 4-day female
21
testis, mated 4-day male
19
accessory gland, mated 4-day male
42
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to Moderate expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
18
central nervous system, larvae L3
22
central nervous system, pupae P8
(32)
head, virgin 1-day female
24
head, virgin 4-day female
19
head, virgin 20-day female
(29)
head, mated 1-day female
13
head, mated 4-day female
19
head, mated 20-day female
21
head, mated 1-day male
(28)
head, mated 4-day male
(30)
head, mated 20-day male
(37)
salivary gland, larvae L3 wandering
12
salivary gland, white prepupae
12
digestive system, larvae L3 wandering
25
digestive system, 1-day adult
25
digestive system, 4-day adult
18
digestive system, 20-day adult
18
fat body, larvae L3 wandering
13
fat body, white prepupae
16
fat body, pupae P8
(30)
carcass, larvae L3 wandering
19
carcass, 1-day adult
12
carcass, 4-day adult
14
carcass, 20-day adult
15
ovary, virgin 4-day female
(28)
ovary, mated 4-day female
21
testis, mated 4-day male
19
accessory gland, mated 4-day male
(42)
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
18
central nervous system, larvae L3
22
central nervous system, pupae P8
32
head, virgin 1-day female
24
head, virgin 4-day female
19
head, virgin 20-day female
29
head, mated 1-day female
13
head, mated 4-day female
19
head, mated 20-day female
21
head, mated 1-day male
28
head, mated 4-day male
30
head, mated 20-day male
37
salivary gland, larvae L3 wandering
12
salivary gland, white prepupae
12
digestive system, larvae L3 wandering
25
digestive system, 1-day adult
25
digestive system, 4-day adult
18
digestive system, 20-day adult
18
fat body, larvae L3 wandering
13
fat body, white prepupae
16
fat body, pupae P8
30
carcass, larvae L3 wandering
19
carcass, 1-day adult
12
carcass, 4-day adult
14
carcass, 20-day adult
15
ovary, virgin 4-day female
28
ovary, mated 4-day female
21
testis, mated 4-day male
19
accessory gland, mated 4-day male
42
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
18
central nervous system, larvae L3
22
central nervous system, pupae P8
32
head, virgin 1-day female
24
head, virgin 4-day female
19
head, virgin 20-day female
29
head, mated 1-day female
13
head, mated 4-day female
19
head, mated 20-day female
21
head, mated 1-day male
28
head, mated 4-day male
30
head, mated 20-day male
37
salivary gland, larvae L3 wandering
12
salivary gland, white prepupae
12
digestive system, larvae L3 wandering
25
digestive system, 1-day adult
25
digestive system, 4-day adult
18
digestive system, 20-day adult
18
fat body, larvae L3 wandering
13
fat body, white prepupae
16
fat body, pupae P8
30
carcass, larvae L3 wandering
19
carcass, 1-day adult
12
carcass, 4-day adult
14
carcass, 20-day adult
15
ovary, virgin 4-day female
28
ovary, mated 4-day female
21
testis, mated 4-day male
19
accessory gland, mated 4-day male
42
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Tissue
Expression Level
imaginal disc, larvae L3 wandering
18
central nervous system, larvae L3
22
central nervous system, pupae P8
32
head, virgin 1-day female
24
head, virgin 4-day female
19
head, virgin 20-day female
29
head, mated 1-day female
13
head, mated 4-day female
19
head, mated 20-day female
21
head, mated 1-day male
28
head, mated 4-day male
30
head, mated 20-day male
37
salivary gland, larvae L3 wandering
12
salivary gland, white prepupae
12
digestive system, larvae L3 wandering
25
digestive system, 1-day adult
25
digestive system, 4-day adult
18
digestive system, 20-day adult
18
fat body, larvae L3 wandering
13
fat body, white prepupae
16
fat body, pupae P8
30
carcass, larvae L3 wandering
19
carcass, 1-day adult
12
carcass, 4-day adult
14
carcass, 20-day adult
15
ovary, virgin 4-day female
28
ovary, mated 4-day female
21
testis, mated 4-day male
19
accessory gland, mated 4-day male
42
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
log, scaled to Moderate expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
18
central nervous system, larvae L3
22
central nervous system, pupae P8
32
head, virgin 1-day female
24
head, virgin 4-day female
19
head, virgin 20-day female
29
head, mated 1-day female
13
head, mated 4-day female
19
head, mated 20-day female
21
head, mated 1-day male
28
head, mated 4-day male
30
head, mated 20-day male
(37)
salivary gland, larvae L3 wandering
12
salivary gland, white prepupae
12
digestive system, larvae L3 wandering
25
digestive system, 1-day adult
25
digestive system, 4-day adult
18
digestive system, 20-day adult
18
fat body, larvae L3 wandering
13
fat body, white prepupae
16
fat body, pupae P8
30
carcass, larvae L3 wandering
19
carcass, 1-day adult
12
carcass, 4-day adult
14
carcass, 20-day adult
15
ovary, virgin 4-day female
28
ovary, mated 4-day female
21
testis, mated 4-day male
19
accessory gland, mated 4-day male
(42)
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
18
central nervous system, larvae L3
22
central nervous system, pupae P8
32
head, virgin 1-day female
24
head, virgin 4-day female
19
head, virgin 20-day female
29
head, mated 1-day female
13
head, mated 4-day female
19
head, mated 20-day female
21
head, mated 1-day male
28
head, mated 4-day male
30
head, mated 20-day male
37
salivary gland, larvae L3 wandering
12
salivary gland, white prepupae
12
digestive system, larvae L3 wandering
25
digestive system, 1-day adult
25
digestive system, 4-day adult
18
digestive system, 20-day adult
18
fat body, larvae L3 wandering
13
fat body, white prepupae
16
fat body, pupae P8
30
carcass, larvae L3 wandering
19
carcass, 1-day adult
12
carcass, 4-day adult
14
carcass, 20-day adult
15
ovary, virgin 4-day female
28
ovary, mated 4-day female
21
testis, mated 4-day male
19
accessory gland, mated 4-day male
42
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
18
central nervous system, larvae L3
22
central nervous system, pupae P8
32
head, virgin 1-day female
24
head, virgin 4-day female
19
head, virgin 20-day female
29
head, mated 1-day female
13
head, mated 4-day female
19
head, mated 20-day female
21
head, mated 1-day male
28
head, mated 4-day male
30
head, mated 20-day male
37
salivary gland, larvae L3 wandering
12
salivary gland, white prepupae
12
digestive system, larvae L3 wandering
25
digestive system, 1-day adult
25
digestive system, 4-day adult
18
digestive system, 20-day adult
18
fat body, larvae L3 wandering
13
fat body, white prepupae
16
fat body, pupae P8
30
carcass, larvae L3 wandering
19
carcass, 1-day adult
12
carcass, 4-day adult
14
carcass, 20-day adult
15
ovary, virgin 4-day female
28
ovary, mated 4-day female
21
testis, mated 4-day male
19
accessory gland, mated 4-day male
42
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Tissue
Expression Level
imaginal disc, larvae L3 wandering
central nervous system, larvae L3
central nervous system, pupae P8
head, virgin 1-day female
head, virgin 4-day female
head, virgin 20-day female
head, mated 1-day female
head, mated 4-day female
head, mated 20-day female
head, mated 1-day male
head, mated 4-day male
head, mated 20-day male
salivary gland, larvae L3 wandering
salivary gland, white prepupae
digestive system, larvae L3 wandering
digestive system, 1-day adult
digestive system, 4-day adult
digestive system, 20-day adult
fat body, larvae L3 wandering
fat body, white prepupae
fat body, pupae P8
carcass, larvae L3 wandering
carcass, 1-day adult
carcass, 4-day adult
carcass, 20-day adult
ovary, virgin 4-day female
ovary, mated 4-day female
testis, mated 4-day male
accessory gland, mated 4-day male
modENCODE Development RNA-Seq
Linear, scaled to maximum expression level
Developmental Stage
Expression Level
embryo 00-02hr
35
embryo 02-04hr
22
embryo 04-06hr
56
embryo 06-08hr
69
embryo 08-10hr
68
embryo 10-12hr
93
embryo 12-14hr
63
embryo 14-16hr
49
embryo 16-18hr
46
embryo 18-20hr
32
embryo 20-22hr
23
embryo 22-24hr
26
larva L1
28
larva L2
36
larva L3 12hr old
34
larva L3 puffstage 1-2
38
larva L3 puffstage 3-6
35
larva L3 puffstage 7-9
37
white prepupae new
34
white prepupae 12hr
31
white prepupae 24hr
36
pupae 2d postWPP
36
pupae 3d postWPP
31
pupae 4d postWPP
19
adult male 01day
29
adult male 05day
29
adult male 30day
28
adult female 01day
34
adult female 05day
40
adult female 30day
39
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Moderate expression
Developmental Stage
Expression Level
embryo 00-02hr
(35)
embryo 02-04hr
22
embryo 04-06hr
(56)
embryo 06-08hr
(69)
embryo 08-10hr
(68)
embryo 10-12hr
(93)
embryo 12-14hr
(63)
embryo 14-16hr
(49)
embryo 16-18hr
(46)
embryo 18-20hr
(32)
embryo 20-22hr
23
embryo 22-24hr
26
larva L1
(28)
larva L2
(36)
larva L3 12hr old
(34)
larva L3 puffstage 1-2
(38)
larva L3 puffstage 3-6
(35)
larva L3 puffstage 7-9
(37)
white prepupae new
(34)
white prepupae 12hr
(31)
white prepupae 24hr
(36)
pupae 2d postWPP
(36)
pupae 3d postWPP
(31)
pupae 4d postWPP
19
adult male 01day
(29)
adult male 05day
(29)
adult male 30day
(28)
adult female 01day
(34)
adult female 05day
(40)
adult female 30day
(39)
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Developmental Stage
Expression Level
embryo 00-02hr
35
embryo 02-04hr
22
embryo 04-06hr
56
embryo 06-08hr
69
embryo 08-10hr
68
embryo 10-12hr
93
embryo 12-14hr
63
embryo 14-16hr
49
embryo 16-18hr
46
embryo 18-20hr
32
embryo 20-22hr
23
embryo 22-24hr
26
larva L1
28
larva L2
36
larva L3 12hr old
34
larva L3 puffstage 1-2
38
larva L3 puffstage 3-6
35
larva L3 puffstage 7-9
37
white prepupae new
34
white prepupae 12hr
31
white prepupae 24hr
36
pupae 2d postWPP
36
pupae 3d postWPP
31
pupae 4d postWPP
19
adult male 01day
29
adult male 05day
29
adult male 30day
28
adult female 01day
34
adult female 05day
40
adult female 30day
39
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Developmental Stage
Expression Level
embryo 00-02hr
35
embryo 02-04hr
22
embryo 04-06hr
56
embryo 06-08hr
69
embryo 08-10hr
68
embryo 10-12hr
93
embryo 12-14hr
63
embryo 14-16hr
49
embryo 16-18hr
46
embryo 18-20hr
32
embryo 20-22hr
23
embryo 22-24hr
26
larva L1
28
larva L2
36
larva L3 12hr old
34
larva L3 puffstage 1-2
38
larva L3 puffstage 3-6
35
larva L3 puffstage 7-9
37
white prepupae new
34
white prepupae 12hr
31
white prepupae 24hr
36
pupae 2d postWPP
36
pupae 3d postWPP
31
pupae 4d postWPP
19
adult male 01day
29
adult male 05day
29
adult male 30day
28
adult female 01day
34
adult female 05day
40
adult female 30day
39
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Developmental Stage
Expression Level
embryo 00-02hr
35
embryo 02-04hr
22
embryo 04-06hr
56
embryo 06-08hr
69
embryo 08-10hr
68
embryo 10-12hr
93
embryo 12-14hr
63
embryo 14-16hr
49
embryo 16-18hr
46
embryo 18-20hr
32
embryo 20-22hr
23
embryo 22-24hr
26
larva L1
28
larva L2
36
larva L3 12hr old
34
larva L3 puffstage 1-2
38
larva L3 puffstage 3-6
35
larva L3 puffstage 7-9
37
white prepupae new
34
white prepupae 12hr
31
white prepupae 24hr
36
pupae 2d postWPP
36
pupae 3d postWPP
31
pupae 4d postWPP
19
adult male 01day
29
adult male 05day
29
adult male 30day
28
adult female 01day
34
adult female 05day
40
adult female 30day
39
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Moderate expression
Developmental Stage
Expression Level
embryo 00-02hr
(35)
embryo 02-04hr
22
embryo 04-06hr
(56)
embryo 06-08hr
(69)
embryo 08-10hr
(68)
embryo 10-12hr
(93)
embryo 12-14hr
(63)
embryo 14-16hr
(49)
embryo 16-18hr
(46)
embryo 18-20hr
32
embryo 20-22hr
23
embryo 22-24hr
26
larva L1
28
larva L2
(36)
larva L3 12hr old
(34)
larva L3 puffstage 1-2
(38)
larva L3 puffstage 3-6
(35)
larva L3 puffstage 7-9
(37)
white prepupae new
(34)
white prepupae 12hr
31
white prepupae 24hr
(36)
pupae 2d postWPP
(36)
pupae 3d postWPP
31
pupae 4d postWPP
19
adult male 01day
29
adult male 05day
29
adult male 30day
28
adult female 01day
(34)
adult female 05day
(40)
adult female 30day
(39)
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Developmental Stage
Expression Level
embryo 00-02hr
35
embryo 02-04hr
22
embryo 04-06hr
56
embryo 06-08hr
69
embryo 08-10hr
68
embryo 10-12hr
93
embryo 12-14hr
63
embryo 14-16hr
49
embryo 16-18hr
46
embryo 18-20hr
32
embryo 20-22hr
23
embryo 22-24hr
26
larva L1
28
larva L2
36
larva L3 12hr old
34
larva L3 puffstage 1-2
38
larva L3 puffstage 3-6
35
larva L3 puffstage 7-9
37
white prepupae new
34
white prepupae 12hr
31
white prepupae 24hr
36
pupae 2d postWPP
36
pupae 3d postWPP
31
pupae 4d postWPP
19
adult male 01day
29
adult male 05day
29
adult male 30day
28
adult female 01day
34
adult female 05day
40
adult female 30day
39
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Developmental Stage
Expression Level
embryo 00-02hr
35
embryo 02-04hr
22
embryo 04-06hr
56
embryo 06-08hr
69
embryo 08-10hr
68
embryo 10-12hr
93
embryo 12-14hr
63
embryo 14-16hr
49
embryo 16-18hr
46
embryo 18-20hr
32
embryo 20-22hr
23
embryo 22-24hr
26
larva L1
28
larva L2
36
larva L3 12hr old
34
larva L3 puffstage 1-2
38
larva L3 puffstage 3-6
35
larva L3 puffstage 7-9
37
white prepupae new
34
white prepupae 12hr
31
white prepupae 24hr
36
pupae 2d postWPP
36
pupae 3d postWPP
31
pupae 4d postWPP
19
adult male 01day
29
adult male 05day
29
adult male 30day
28
adult female 01day
34
adult female 05day
40
adult female 30day
39
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Developmental Stage
Expression Level
embryo 00-02hr
embryo 02-04hr
embryo 04-06hr
embryo 06-08hr
embryo 08-10hr
embryo 10-12hr
embryo 12-14hr
embryo 14-16hr
embryo 16-18hr
embryo 18-20hr
embryo 20-22hr
embryo 22-24hr
larva L1
larva L2
larva L3 12hr old
larva L3 puffstage 1-2
larva L3 puffstage 3-6
larva L3 puffstage 7-9
white prepupae new
white prepupae 12hr
white prepupae 24hr
pupae 2d postWPP
pupae 3d postWPP
pupae 4d postWPP
adult male 01day
adult male 05day
adult male 30day
adult female 01day
adult female 05day
adult female 30day
modENCODE Cell Lines RNA-Seq
Linear, scaled to maximum expression level
Cell Line
Expression Level
Schneider line 2 S2R+
93
Schneider line 2 Sg4
92
embryonic 1182-4H
38
embryonic GM2
63
embryonic Kc167
79
embryonic S1
37
embryonic S3
81
leg disc CME L1
60
wing disc CME-W2
84
wing disc ML-DmD8
21
wing disc ML-DmD9
42
wing disc ML-DmD16-c3
41
wing disc ML-DmD21
46
wing disc ML-DmD32
37
haltere disc ML-DmD17-c3
46
eye-antennal disc ML-DmD11
38
antennal disc ML-DmD20-c5
88
mixed discs ML-DmD4-c1
70
CNS ML-DmBG1-c1
46
CNS ML-DmBG2-c2
59
tumorous blood cells mbn2
53
ovary fGS/OSS
21
ovary OSC
15
ovary OSS
10
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Moderate expression
Cell Line
Expression Level
Schneider line 2 S2R+
(93)
Schneider line 2 Sg4
(92)
embryonic 1182-4H
(38)
embryonic GM2
(63)
embryonic Kc167
(79)
embryonic S1
(37)
embryonic S3
(81)
leg disc CME L1
(60)
wing disc CME-W2
(84)
wing disc ML-DmD8
21
wing disc ML-DmD9
(42)
wing disc ML-DmD16-c3
(41)
wing disc ML-DmD21
(46)
wing disc ML-DmD32
(37)
haltere disc ML-DmD17-c3
(46)
eye-antennal disc ML-DmD11
(38)
antennal disc ML-DmD20-c5
(88)
mixed discs ML-DmD4-c1
(70)
CNS ML-DmBG1-c1
(46)
CNS ML-DmBG2-c2
(59)
tumorous blood cells mbn2
(53)
ovary fGS/OSS
21
ovary OSC
15
ovary OSS
10
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Cell Line
Expression Level
Schneider line 2 S2R+
93
Schneider line 2 Sg4
92
embryonic 1182-4H
38
embryonic GM2
63
embryonic Kc167
79
embryonic S1
37
embryonic S3
81
leg disc CME L1
60
wing disc CME-W2
84
wing disc ML-DmD8
21
wing disc ML-DmD9
42
wing disc ML-DmD16-c3
41
wing disc ML-DmD21
46
wing disc ML-DmD32
37
haltere disc ML-DmD17-c3
46
eye-antennal disc ML-DmD11
38
antennal disc ML-DmD20-c5
88
mixed discs ML-DmD4-c1
70
CNS ML-DmBG1-c1
46
CNS ML-DmBG2-c2
59
tumorous blood cells mbn2
53
ovary fGS/OSS
21
ovary OSC
15
ovary OSS
10
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Cell Line
Expression Level
Schneider line 2 S2R+
93
Schneider line 2 Sg4
92
embryonic 1182-4H
38
embryonic GM2
63
embryonic Kc167
79
embryonic S1
37
embryonic S3
81
leg disc CME L1
60
wing disc CME-W2
84
wing disc ML-DmD8
21
wing disc ML-DmD9
42
wing disc ML-DmD16-c3
41
wing disc ML-DmD21
46
wing disc ML-DmD32
37
haltere disc ML-DmD17-c3
46
eye-antennal disc ML-DmD11
38
antennal disc ML-DmD20-c5
88
mixed discs ML-DmD4-c1
70
CNS ML-DmBG1-c1
46
CNS ML-DmBG2-c2
59
tumorous blood cells mbn2
53
ovary fGS/OSS
21
ovary OSC
15
ovary OSS
10
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Cell Line
Expression Level
Schneider line 2 S2R+
93
Schneider line 2 Sg4
92
embryonic 1182-4H
38
embryonic GM2
63
embryonic Kc167
79
embryonic S1
37
embryonic S3
81
leg disc CME L1
60
wing disc CME-W2
84
wing disc ML-DmD8
21
wing disc ML-DmD9
42
wing disc ML-DmD16-c3
41
wing disc ML-DmD21
46
wing disc ML-DmD32
37
haltere disc ML-DmD17-c3
46
eye-antennal disc ML-DmD11
38
antennal disc ML-DmD20-c5
88
mixed discs ML-DmD4-c1
70
CNS ML-DmBG1-c1
46
CNS ML-DmBG2-c2
59
tumorous blood cells mbn2
53
ovary fGS/OSS
21
ovary OSC
15
ovary OSS
10
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Moderate expression
Cell Line
Expression Level
Schneider line 2 S2R+
(93)
Schneider line 2 Sg4
(92)
embryonic 1182-4H
(38)
embryonic GM2
(63)
embryonic Kc167
(79)
embryonic S1
(37)
embryonic S3
(81)
leg disc CME L1
(60)
wing disc CME-W2
(84)
wing disc ML-DmD8
21
wing disc ML-DmD9
(42)
wing disc ML-DmD16-c3
(41)
wing disc ML-DmD21
(46)
wing disc ML-DmD32
(37)
haltere disc ML-DmD17-c3
(46)
eye-antennal disc ML-DmD11
(38)
antennal disc ML-DmD20-c5
(88)
mixed discs ML-DmD4-c1
(70)
CNS ML-DmBG1-c1
(46)
CNS ML-DmBG2-c2
(59)
tumorous blood cells mbn2
(53)
ovary fGS/OSS
21
ovary OSC
15
ovary OSS
10
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Cell Line
Expression Level
Schneider line 2 S2R+
93
Schneider line 2 Sg4
92
embryonic 1182-4H
38
embryonic GM2
63
embryonic Kc167
79
embryonic S1
37
embryonic S3
81
leg disc CME L1
60
wing disc CME-W2
84
wing disc ML-DmD8
21
wing disc ML-DmD9
42
wing disc ML-DmD16-c3
41
wing disc ML-DmD21
46
wing disc ML-DmD32
37
haltere disc ML-DmD17-c3
46
eye-antennal disc ML-DmD11
38
antennal disc ML-DmD20-c5
88
mixed discs ML-DmD4-c1
70
CNS ML-DmBG1-c1
46
CNS ML-DmBG2-c2
59
tumorous blood cells mbn2
53
ovary fGS/OSS
21
ovary OSC
15
ovary OSS
10
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Cell Line
Expression Level
Schneider line 2 S2R+
93
Schneider line 2 Sg4
92
embryonic 1182-4H
38
embryonic GM2
63
embryonic Kc167
79
embryonic S1
37
embryonic S3
81
leg disc CME L1
60
wing disc CME-W2
84
wing disc ML-DmD8
21
wing disc ML-DmD9
42
wing disc ML-DmD16-c3
41
wing disc ML-DmD21
46
wing disc ML-DmD32
37
haltere disc ML-DmD17-c3
46
eye-antennal disc ML-DmD11
38
antennal disc ML-DmD20-c5
88
mixed discs ML-DmD4-c1
70
CNS ML-DmBG1-c1
46
CNS ML-DmBG2-c2
59
tumorous blood cells mbn2
53
ovary fGS/OSS
21
ovary OSC
15
ovary OSS
10
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Cell Line
Expression Level
Schneider line 2 S2R+
Schneider line 2 Sg4
embryonic 1182-4H
embryonic GM2
embryonic Kc167
embryonic S1
embryonic S3
leg disc CME L1
wing disc CME-W2
wing disc ML-DmD8
wing disc ML-DmD9
wing disc ML-DmD16-c3
wing disc ML-DmD21
wing disc ML-DmD32
haltere disc ML-DmD17-c3
eye-antennal disc ML-DmD11
antennal disc ML-DmD20-c5
mixed discs ML-DmD4-c1
CNS ML-DmBG1-c1
CNS ML-DmBG2-c2
tumorous blood cells mbn2
ovary fGS/OSS
ovary OSC
ovary OSS
modENCODE Treatments RNA-Seq
Linear, scaled to maximum expression level
Treatment
Expression Level
extended cold, 4-day adult
7
cold shock, 4-day adult
6
heat shock, 4-day adult
21
Cadmium 50 mM 6 hrs, larvae L3
29
Cadmium 50 mM 12 hrs, larvae L3
32
Cadmium 50 mM 48 hrs, 4-day adult
17
Cadmium 100 mM 48 hrs, 4-day adult
16
Copper 0.5 mM 12 hrs, larvae L3
8
Copper 15 mM 48 hrs, 4-day adult
9
Zinc 5 mM 12 hrs, larvae L3
10
Zinc 4.5 mM 48 hrs, 4-day adult
10
Ethanol 2.5% 3 hrs, larvae L3
21
Ethanol 5% 3 hrs, larvae L3
33
Ethanol 10% 3 hrs, larvae L3
26
Caffeine 1.5 mg/ml 4 hrs, larvae L3
31
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
16
Caffeine 25 mg/ml 48 hrs, 4-day adult
6
Paraquat 5 mM 48 hrs, 4-day adult
19
Paraquat 10 mM 48 hrs, 4-day adult
20
Rotenone 2 μg 12 hrs, larvae L3
37
Rotenone 8 μg 12 hrs, larvae L3
23
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to Moderate expression
Treatment
Expression Level
extended cold, 4-day adult
7
cold shock, 4-day adult
6
heat shock, 4-day adult
21
Cadmium 50 mM 6 hrs, larvae L3
(29)
Cadmium 50 mM 12 hrs, larvae L3
(32)
Cadmium 50 mM 48 hrs, 4-day adult
17
Cadmium 100 mM 48 hrs, 4-day adult
16
Copper 0.5 mM 12 hrs, larvae L3
8
Copper 15 mM 48 hrs, 4-day adult
9
Zinc 5 mM 12 hrs, larvae L3
10
Zinc 4.5 mM 48 hrs, 4-day adult
10
Ethanol 2.5% 3 hrs, larvae L3
21
Ethanol 5% 3 hrs, larvae L3
(33)
Ethanol 10% 3 hrs, larvae L3
26
Caffeine 1.5 mg/ml 4 hrs, larvae L3
(31)
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
16
Caffeine 25 mg/ml 48 hrs, 4-day adult
6
Paraquat 5 mM 48 hrs, 4-day adult
19
Paraquat 10 mM 48 hrs, 4-day adult
20
Rotenone 2 μg 12 hrs, larvae L3
(37)
Rotenone 8 μg 12 hrs, larvae L3
23
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Treatment
Expression Level
extended cold, 4-day adult
7
cold shock, 4-day adult
6
heat shock, 4-day adult
21
Cadmium 50 mM 6 hrs, larvae L3
29
Cadmium 50 mM 12 hrs, larvae L3
32
Cadmium 50 mM 48 hrs, 4-day adult
17
Cadmium 100 mM 48 hrs, 4-day adult
16
Copper 0.5 mM 12 hrs, larvae L3
8
Copper 15 mM 48 hrs, 4-day adult
9
Zinc 5 mM 12 hrs, larvae L3
10
Zinc 4.5 mM 48 hrs, 4-day adult
10
Ethanol 2.5% 3 hrs, larvae L3
21
Ethanol 5% 3 hrs, larvae L3
33
Ethanol 10% 3 hrs, larvae L3
26
Caffeine 1.5 mg/ml 4 hrs, larvae L3
31
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
16
Caffeine 25 mg/ml 48 hrs, 4-day adult
6
Paraquat 5 mM 48 hrs, 4-day adult
19
Paraquat 10 mM 48 hrs, 4-day adult
20
Rotenone 2 μg 12 hrs, larvae L3
37
Rotenone 8 μg 12 hrs, larvae L3
23
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Treatment
Expression Level
extended cold, 4-day adult
7
cold shock, 4-day adult
6
heat shock, 4-day adult
21
Cadmium 50 mM 6 hrs, larvae L3
29
Cadmium 50 mM 12 hrs, larvae L3
32
Cadmium 50 mM 48 hrs, 4-day adult
17
Cadmium 100 mM 48 hrs, 4-day adult
16
Copper 0.5 mM 12 hrs, larvae L3
8
Copper 15 mM 48 hrs, 4-day adult
9
Zinc 5 mM 12 hrs, larvae L3
10
Zinc 4.5 mM 48 hrs, 4-day adult
10
Ethanol 2.5% 3 hrs, larvae L3
21
Ethanol 5% 3 hrs, larvae L3
33
Ethanol 10% 3 hrs, larvae L3
26
Caffeine 1.5 mg/ml 4 hrs, larvae L3
31
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
16
Caffeine 25 mg/ml 48 hrs, 4-day adult
6
Paraquat 5 mM 48 hrs, 4-day adult
19
Paraquat 10 mM 48 hrs, 4-day adult
20
Rotenone 2 μg 12 hrs, larvae L3
37
Rotenone 8 μg 12 hrs, larvae L3
23
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Treatment
Expression Level
extended cold, 4-day adult
7
cold shock, 4-day adult
6
heat shock, 4-day adult
21
Cadmium 50 mM 6 hrs, larvae L3
29
Cadmium 50 mM 12 hrs, larvae L3
32
Cadmium 50 mM 48 hrs, 4-day adult
17
Cadmium 100 mM 48 hrs, 4-day adult
16
Copper 0.5 mM 12 hrs, larvae L3
8
Copper 15 mM 48 hrs, 4-day adult
9
Zinc 5 mM 12 hrs, larvae L3
10
Zinc 4.5 mM 48 hrs, 4-day adult
10
Ethanol 2.5% 3 hrs, larvae L3
21
Ethanol 5% 3 hrs, larvae L3
33
Ethanol 10% 3 hrs, larvae L3
26
Caffeine 1.5 mg/ml 4 hrs, larvae L3
31
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
16
Caffeine 25 mg/ml 48 hrs, 4-day adult
6
Paraquat 5 mM 48 hrs, 4-day adult
19
Paraquat 10 mM 48 hrs, 4-day adult
20
Rotenone 2 μg 12 hrs, larvae L3
37
Rotenone 8 μg 12 hrs, larvae L3
23
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
log, scaled to Moderate expression
Treatment
Expression Level
extended cold, 4-day adult
7
cold shock, 4-day adult
6
heat shock, 4-day adult
21
Cadmium 50 mM 6 hrs, larvae L3
29
Cadmium 50 mM 12 hrs, larvae L3
32
Cadmium 50 mM 48 hrs, 4-day adult
17
Cadmium 100 mM 48 hrs, 4-day adult
16
Copper 0.5 mM 12 hrs, larvae L3
8
Copper 15 mM 48 hrs, 4-day adult
9
Zinc 5 mM 12 hrs, larvae L3
10
Zinc 4.5 mM 48 hrs, 4-day adult
10
Ethanol 2.5% 3 hrs, larvae L3
21
Ethanol 5% 3 hrs, larvae L3
(33)
Ethanol 10% 3 hrs, larvae L3
26
Caffeine 1.5 mg/ml 4 hrs, larvae L3
31
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
16
Caffeine 25 mg/ml 48 hrs, 4-day adult
6
Paraquat 5 mM 48 hrs, 4-day adult
19
Paraquat 10 mM 48 hrs, 4-day adult
20
Rotenone 2 μg 12 hrs, larvae L3
(37)
Rotenone 8 μg 12 hrs, larvae L3
23
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Treatment
Expression Level
extended cold, 4-day adult
7
cold shock, 4-day adult
6
heat shock, 4-day adult
21
Cadmium 50 mM 6 hrs, larvae L3
29
Cadmium 50 mM 12 hrs, larvae L3
32
Cadmium 50 mM 48 hrs, 4-day adult
17
Cadmium 100 mM 48 hrs, 4-day adult
16
Copper 0.5 mM 12 hrs, larvae L3
8
Copper 15 mM 48 hrs, 4-day adult
9
Zinc 5 mM 12 hrs, larvae L3
10
Zinc 4.5 mM 48 hrs, 4-day adult
10
Ethanol 2.5% 3 hrs, larvae L3
21
Ethanol 5% 3 hrs, larvae L3
33
Ethanol 10% 3 hrs, larvae L3
26
Caffeine 1.5 mg/ml 4 hrs, larvae L3
31
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
16
Caffeine 25 mg/ml 48 hrs, 4-day adult
6
Paraquat 5 mM 48 hrs, 4-day adult
19
Paraquat 10 mM 48 hrs, 4-day adult
20
Rotenone 2 μg 12 hrs, larvae L3
37
Rotenone 8 μg 12 hrs, larvae L3
23
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Treatment
Expression Level
extended cold, 4-day adult
7
cold shock, 4-day adult
6
heat shock, 4-day adult
21
Cadmium 50 mM 6 hrs, larvae L3
29
Cadmium 50 mM 12 hrs, larvae L3
32
Cadmium 50 mM 48 hrs, 4-day adult
17
Cadmium 100 mM 48 hrs, 4-day adult
16
Copper 0.5 mM 12 hrs, larvae L3
8
Copper 15 mM 48 hrs, 4-day adult
9
Zinc 5 mM 12 hrs, larvae L3
10
Zinc 4.5 mM 48 hrs, 4-day adult
10
Ethanol 2.5% 3 hrs, larvae L3
21
Ethanol 5% 3 hrs, larvae L3
33
Ethanol 10% 3 hrs, larvae L3
26
Caffeine 1.5 mg/ml 4 hrs, larvae L3
31
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
16
Caffeine 25 mg/ml 48 hrs, 4-day adult
6
Paraquat 5 mM 48 hrs, 4-day adult
19
Paraquat 10 mM 48 hrs, 4-day adult
20
Rotenone 2 μg 12 hrs, larvae L3
37
Rotenone 8 μg 12 hrs, larvae L3
23
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Treatment
Expression Level
extended cold, 4-day adult
cold shock, 4-day adult
heat shock, 4-day adult
Cadmium 50 mM 6 hrs, larvae L3
Cadmium 50 mM 12 hrs, larvae L3
Cadmium 50 mM 48 hrs, 4-day adult
Cadmium 100 mM 48 hrs, 4-day adult
Copper 0.5 mM 12 hrs, larvae L3
Copper 15 mM 48 hrs, 4-day adult
Zinc 5 mM 12 hrs, larvae L3
Zinc 4.5 mM 48 hrs, 4-day adult
Ethanol 2.5% 3 hrs, larvae L3
Ethanol 5% 3 hrs, larvae L3
Ethanol 10% 3 hrs, larvae L3
Caffeine 1.5 mg/ml 4 hrs, larvae L3
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
Caffeine 25 mg/ml 48 hrs, 4-day adult
Paraquat 5 mM 48 hrs, 4-day adult
Paraquat 10 mM 48 hrs, 4-day adult
Rotenone 2 μg 12 hrs, larvae L3
Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
A cluster of genes with similar mRNA expression dynamics across development.
External Data & Images
Linkouts
- Cell culture data for RNAi and other high-throughput technologies
- Adult expression by tissue, using Affymetrix Dros2 array
Alleles & Phenotypes Summary of Allele Phenotypes Classical Alleles ( 1 ) For All Classical Alleles Show Alleles Carried on Transgenic Constructs
( 2 ) For All Alleles Carried on Transgenic
Constructs Show Aneuploid Aberrations Transgenic Constructs & Insertions
Transgenic Constructs Insertions insertion of mobile activating element
Gene Ontology: Function, Process
& Cellular Component ( 3 unique terms ) Terms Based on
Experimental Evidence ( 1 term ) Molecular Function ( 0 terms) Biological Process inferred from mutant phenotype
Cellular Component ( 0 terms) Terms Based on Predictions or
Assertions ( 2 terms ) Molecular Function Biological Process Cellular Component ( 0 terms) Sequence Ontology: Class of Gene Interactions & Pathways
Summary of Physical Interactions
protein-protein anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
experimental knowledge based
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
Summary of Genetic Interactions Interacts with Please look at the allele data
for full details of the genetic interactions
External Data Linkouts
- A database of protein and genetic interactions
- DPiM, Drosophila Protein interaction Map
- A comprehensive database of gene and protein interactions.
Protein-protein interactions (PPI) from both known and predicted PPI data sets.
Orthologs
OrthoDB Orthologs (40)
- based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
OrthoDB orthology group searches
Drosophila inclusive ortholog search
Dipteran inclusive ortholog search
Insect inclusive ortholog search
Arthropod inclusive ortholog search
Metazoa inclusive ortholog search
Orthologs in Drosophila Species
(EOG6G4H94 )
Drosophila melanogaster
fruit fly
Drosophila pseudoobscura pseudoobscura
Y
Orthologs in non-Drosophila Dipterans
(EOG6HDT2W )
Aedes aegypti
Yellow fever mosquito
Anopheles gambiae
Malaria mosquito
Culex quinquefasciatus
Southern house mosquito
Orthologs in non-Dipteran Insects
(EOG6QNKRX )
Apis mellifera
Western honey bee
Amel\GB54328
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG009368
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG007192
Acromyrmex echinatior
Panamanian leafcutter ant
Aech\AECH19092
Atta cephalotes
Leafcutter ant
Acep\ACEP19685
Camponotus floridanus
Florida carpenter ant
Cflo\CFLO13293
Harpegnathos saltator
Jerdons jumping ant
Hsal\HSAL19573
Linepithema humile
Argentine ant
Lhum\LH24451
Pogonomyrmex barbatus
Red harvester ant
Pbar\PB24987
Solenopsis invicta
Red fire ant
Sinv\SINV22640
Acyrthosiphon pisum
Pea aphid
Pediculus humanus
Human body louse
Tribolium castaneum
Red flour beetle
Orthologs in non-Insect Arthropods
(EOG6TX97K )
Ixodes scapularis
Deer tick
Orthologs in non-Arthropod Metazoa
(EOG6MWN10 )
Caenorhabditis elegans
Nematode
Strongylocentrotus purpuratus
Purple sea urchin
Xenopus tropicalis
Western clawed frog
Gallus gallus
Domestic chicken
Rattus norvegicus
Norway rat
Rattus norvegicus
Norway rat
Human Orthologs (0)AAA Orthologs (10)
based on analysis using Dmel annotation version 4.3
Drosophila pseudoobscura pseudoobscura
Stocks & Reagents Stocks Listed in FlyBase ( 4 )Bloomington VDRC Genomic Clones ( 1 )Please Note FlyBase no
longer curates genomic clone accessions so this list
may not be complete
cDNA Clones ( 75 )Please Note This section lists
cDNAs and ESTs that fall within the genomic extent
of the gene model, which may include cDNAs and ESTs
of genes within introns, or of overlapping genes.
Please see
GBrowse for alignment of the cDNAs and ESTs
to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones Other clones cDNA Clones, End Sequenced
(ESTs) BDGP DGC clones Other clones RNAi & Array Information Linkouts
- Results from RNAi screens.
- GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents
Antibody Information
Other Information Discoverer Etymology Identification Relationship to Other Genes Source for database identity of Source for database merge of Additional comments Other Comments External Crossreferences & Linkouts
Sequence Crossreferences
- A searchable database of RefSeq genes.
Other Crossreferences
domains - A database of protein families, domains, and functional sites
- Patterns of gene expression in Drosophila embryogenesis
Linkouts
- A database of protein and genetic interactions
- DPiM, Drosophila Protein interaction Map
- A comprehensive database of gene and protein interactions.
- Results from RNAi screens.
- Cell culture data for RNAi and other high-throughput technologies
- Adult expression by tissue, using Affymetrix Dros2 array
- Integrated genomics database for Drosophila, Anopheles, and C.elegans
- GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents
Protein-protein interactions (PPI) from both known and predicted PPI data sets.
- Data generated by the modENCODE project.
Synonyms & Secondary IDs
( 2 )Reported As Symbol Synonym Name Synonym putative alpha-1,2-mannosyltransferase activity
Secondary FlyBase
IDs References ( 19 )Research paper Harbison et al., 2009, Nat. Genet. 41(3): 371--375Co-regulated transcriptional networks contribute to natural genetic variation in Drosophila sleep. [FBrf0206746] Liu and Lehmann, 2008, Insect Mol. Biol. 17(2): 91--101Genes and biological processes controlled by the Drosophila FOXA orthologue Fork head. [FBrf0204414] Accardo et al., 2004, Bioinformatics 20(18): 3293--3301A computational search for box C/D snoRNA genes in the Drosophila melanogaster genome. [FBrf0187185] Supplementary material Graveley et al., 2011, Nature 471(7339): Supplementary Table 33. Fuzzy Cluster Members. [FBrf0213980] Guruharsha et al., 2011, Cell 147(3): Table S3. [FBrf0218395] Neumüller et al., 2011, Cell Stem Cell 8(5): Supplemental Table S1. [FBrf0214431] Khanna et al., 2010, BMC Genomics 11(1): Towards a membrane proteome in Drosophila: a method for the isolation of plasma membrane. [FBrf0210978] The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518] Giot et al., 2003, Science 302(5651): Tables S1 to S7. [FBrf0166452] Personal communication to FlyBase Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi CenterRNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510] Mintseris et al., 2009.11.23, DPiM: the Drosophila Protein Interaction Mapping projectDPiM: the Drosophila Protein Interaction Mapping project [FBrf0209452] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi CenterRNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] FlyBase Curators et al., 2004-, Gene Ontology annotation in FlyBase through association of InterPro records with GO terms.Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. [FBrf0174215] Gene Disruption Project members, 2001-, (Computer file)(Computer file) [FBrf0132177] BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. (Computer file)Berkeley Drosophila Genome Project. (Computer file) [FBrf0125078] FlyBase analysis FlyBase, 1992-, FlyBase curation.FlyBase curation. [FBrf0105495] Website Fisher et al., 2012, BDGP insitu homepageBDGP insitu homepage [FBrf0219073]