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Gene Dmel\CG11306

General Information
Symbol	Dmel\CG11306	Species	D. melanogaster
Name		Annotation symbol	CG11306
Feature type	protein_coding_gene	FlyBase ID	FBgn0037108
Gene Model Status	Current	Stock availability	4 publicly available
Genomic Location
Chromosome (arm)	3L	Recombination map
Cytogenetic map	78E1-78E1	Sequence location	3L:21,619,366..21,621,416 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG11306 (FBgn0037108). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: alpha-1,2-mannosyltransferase activity. There is experimental evidence that it is involved in the biological process: neurogenesis. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Glycosyl transferase, family 1. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderately high expression. Peak expression observed within 00-18 hour embryonic stages. Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult organs/tissues expressed at moderate or high levels. Expression at high levels in the following post-embryonic organs or tissues: adult eye, larval fat body, larval/adult salivary gland, larval trachea, adult spermathecae, adult male accessory gland. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, adult fat body, adult ovary, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1640824_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG11306. Gene sequence location is 3L:21619366..21621416.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2011_10
FB2012_01	Sequence features HFA11647 BKN27035
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 78E1-78E1   Limits computationally determined from genome sequence between P{lacW}l(3)j1B10j1B10 and P{lacW}l(3)j2C4j2C4
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG11306 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG11306-RA FBtr0078422  NM_141083   1563   475
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG11306-PA   FBpp0078076   54.6   475   8.03     NP_649340   AAF51756
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Glycosyl transferase, family 1 (IPR001296)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA695888   AA697479   AA697579   AA698085   AA950237   AE014296 AAF51756   AI135797   AI389661   AI517235   AW941425   AY061012 AAL28560   AY113436 AAM29441   BG636686   BI166304   BI215178   BI229275   BI236296   BI236724   BI236765   BI370143   BI485252   BI615510   BI624845   BP547798   BP557580   BP560391   CL526217   CO156157   CO185590   CO186772   CO189894   CO190284   CO263057   CO268100   CO269681   CO269794   CO282804   CO294531   CO295493   CO305626   CO321718   CO326339   CO333459   CO337248   CO341152   DN153966   EC065957   EC069446   EC070713   EC080301   EC082738   EC090043   EC201486   EC209915   EC210287   EC210970   EC219894   EC220175   EC241293   EC246233   EC247262   EC249395   EC254706   EC260451   EC262417   EC264828   GH740593   GH742628   GH742984   GH747154   GH762059   GH763450   GH763915   GH768412   GH768654   GH769663   GH769704   GH769844
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9VP06
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0037108    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0037108 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderately high expression. Peak expression observed within 00-18 hour embryonic stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0037108 expression level Developmental Stage   Expression Level embryo 00-02hr    2824 embryo 02-04hr    1793 embryo 04-06hr    4489 embryo 06-08hr    5536 embryo 08-10hr    5507 embryo 10-12hr    7532 embryo 12-14hr    5040 embryo 14-16hr    3926 embryo 16-18hr    3686 embryo 18-20hr    2572 embryo 20-22hr    1830 embryo 22-24hr    2049 larva L1    2240 larva L2    2929 larva L3 12hr old    2750 larva L3 puffstage 1-2    3073 larva L3 puffstage 3-6    2843 larva L3 puffstage 7-9    3018 white prepupae new    2715 white prepupae 12hr    2458 white prepupae 24hr    2886 pupae 2d postWPP    2906 pupae 3d postWPP    2481 pupae 4d postWPP    1529 adult male 01day    2326 adult male 05day    2331 adult male 30day    2275 adult female 01day    2701 adult female 05day    3228 adult female 30day    3149 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (2824) embryo 02-04hr  (1793) embryo 04-06hr  (4489) embryo 06-08hr  (5536) embryo 08-10hr  (5507) embryo 10-12hr  (7532) embryo 12-14hr  (5040) embryo 14-16hr  (3926) embryo 16-18hr  (3686) embryo 18-20hr  (2572) embryo 20-22hr  (1830) embryo 22-24hr  (2049) larva L1  (2240) larva L2  (2929) larva L3 12hr old  (2750) larva L3 puffstage 1-2  (3073) larva L3 puffstage 3-6  (2843) larva L3 puffstage 7-9  (3018) white prepupae new  (2715) white prepupae 12hr  (2458) white prepupae 24hr  (2886) pupae 2d postWPP  (2906) pupae 3d postWPP  (2481) pupae 4d postWPP  (1529) adult male 01day  (2326) adult male 05day  (2331) adult male 30day  (2275) adult female 01day  (2701) adult female 05day  (3228) adult female 30day  (3149) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (2824) embryo 02-04hr  (1793) embryo 04-06hr  (4489) embryo 06-08hr  (5536) embryo 08-10hr  (5507) embryo 10-12hr  (7532) embryo 12-14hr  (5040) embryo 14-16hr  (3926) embryo 16-18hr  (3686) embryo 18-20hr  (2572) embryo 20-22hr  (1830) embryo 22-24hr  (2049) larva L1  (2240) larva L2  (2929) larva L3 12hr old  (2750) larva L3 puffstage 1-2  (3073) larva L3 puffstage 3-6  (2843) larva L3 puffstage 7-9  (3018) white prepupae new  (2715) white prepupae 12hr  (2458) white prepupae 24hr  (2886) pupae 2d postWPP  (2906) pupae 3d postWPP  (2481) pupae 4d postWPP  (1529) adult male 01day  (2326) adult male 05day  (2331) adult male 30day  (2275) adult female 01day  (2701) adult female 05day  (3228) adult female 30day  (3149) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    2824 embryo 02-04hr    1793 embryo 04-06hr    4489 embryo 06-08hr    5536 embryo 08-10hr    5507 embryo 10-12hr    7532 embryo 12-14hr    5040 embryo 14-16hr    3926 embryo 16-18hr    3686 embryo 18-20hr    2572 embryo 20-22hr    1830 embryo 22-24hr    2049 larva L1    2240 larva L2    2929 larva L3 12hr old    2750 larva L3 puffstage 1-2    3073 larva L3 puffstage 3-6    2843 larva L3 puffstage 7-9    3018 white prepupae new    2715 white prepupae 12hr    2458 white prepupae 24hr    2886 pupae 2d postWPP    2906 pupae 3d postWPP    2481 pupae 4d postWPP    1529 adult male 01day    2326 adult male 05day    2331 adult male 30day    2275 adult female 01day    2701 adult female 05day    3228 adult female 30day    3149 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    2824 embryo 02-04hr    1793 embryo 04-06hr    4489 embryo 06-08hr    5536 embryo 08-10hr    5507 embryo 10-12hr    7532 embryo 12-14hr    5040 embryo 14-16hr    3926 embryo 16-18hr    3686 embryo 18-20hr    2572 embryo 20-22hr    1830 embryo 22-24hr    2049 larva L1    2240 larva L2    2929 larva L3 12hr old    2750 larva L3 puffstage 1-2    3073 larva L3 puffstage 3-6    2843 larva L3 puffstage 7-9    3018 white prepupae new    2715 white prepupae 12hr    2458 white prepupae 24hr    2886 pupae 2d postWPP    2906 pupae 3d postWPP    2481 pupae 4d postWPP    1529 adult male 01day    2326 adult male 05day    2331 adult male 30day    2275 adult female 01day    2701 adult female 05day    3228 adult female 30day    3149 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0037108 expression level Developmental Stage   Expression Level embryo 00-02hr    2824 embryo 02-04hr    1793 embryo 04-06hr    4489 embryo 06-08hr    5536 embryo 08-10hr    5507 embryo 10-12hr    7532 embryo 12-14hr    5040 embryo 14-16hr    3926 embryo 16-18hr    3686 embryo 18-20hr    2572 embryo 20-22hr    1830 embryo 22-24hr    2049 larva L1    2240 larva L2    2929 larva L3 12hr old    2750 larva L3 puffstage 1-2    3073 larva L3 puffstage 3-6    2843 larva L3 puffstage 7-9    3018 white prepupae new    2715 white prepupae 12hr    2458 white prepupae 24hr    2886 pupae 2d postWPP    2906 pupae 3d postWPP    2481 pupae 4d postWPP    1529 adult male 01day    2326 adult male 05day    2331 adult male 30day    2275 adult female 01day    2701 adult female 05day    3228 adult female 30day    3149 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (2824) embryo 02-04hr  (1793) embryo 04-06hr  (4489) embryo 06-08hr  (5536) embryo 08-10hr  (5507) embryo 10-12hr  (7532) embryo 12-14hr  (5040) embryo 14-16hr  (3926) embryo 16-18hr  (3686) embryo 18-20hr  (2572) embryo 20-22hr  (1830) embryo 22-24hr  (2049) larva L1  (2240) larva L2  (2929) larva L3 12hr old  (2750) larva L3 puffstage 1-2  (3073) larva L3 puffstage 3-6  (2843) larva L3 puffstage 7-9  (3018) white prepupae new  (2715) white prepupae 12hr  (2458) white prepupae 24hr  (2886) pupae 2d postWPP  (2906) pupae 3d postWPP  (2481) pupae 4d postWPP  (1529) adult male 01day  (2326) adult male 05day  (2331) adult male 30day  (2275) adult female 01day  (2701) adult female 05day  (3228) adult female 30day  (3149) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (2824) embryo 02-04hr  1793 embryo 04-06hr  (4489) embryo 06-08hr  (5536) embryo 08-10hr  (5507) embryo 10-12hr  (7532) embryo 12-14hr  (5040) embryo 14-16hr  (3926) embryo 16-18hr  (3686) embryo 18-20hr  (2572) embryo 20-22hr  1830 embryo 22-24hr  2049 larva L1  2240 larva L2  (2929) larva L3 12hr old  (2750) larva L3 puffstage 1-2  (3073) larva L3 puffstage 3-6  (2843) larva L3 puffstage 7-9  (3018) white prepupae new  (2715) white prepupae 12hr  2458 white prepupae 24hr  (2886) pupae 2d postWPP  (2906) pupae 3d postWPP  (2481) pupae 4d postWPP  1529 adult male 01day  2326 adult male 05day  2331 adult male 30day  2275 adult female 01day  (2701) adult female 05day  (3228) adult female 30day  (3149) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    2824 embryo 02-04hr    1793 embryo 04-06hr    4489 embryo 06-08hr    5536 embryo 08-10hr    5507 embryo 10-12hr    7532 embryo 12-14hr    5040 embryo 14-16hr    3926 embryo 16-18hr    3686 embryo 18-20hr    2572 embryo 20-22hr    1830 embryo 22-24hr    2049 larva L1    2240 larva L2    2929 larva L3 12hr old    2750 larva L3 puffstage 1-2    3073 larva L3 puffstage 3-6    2843 larva L3 puffstage 7-9    3018 white prepupae new    2715 white prepupae 12hr    2458 white prepupae 24hr    2886 pupae 2d postWPP    2906 pupae 3d postWPP    2481 pupae 4d postWPP    1529 adult male 01day    2326 adult male 05day    2331 adult male 30day    2275 adult female 01day    2701 adult female 05day    3228 adult female 30day    3149 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    2824 embryo 02-04hr    1793 embryo 04-06hr    4489 embryo 06-08hr    5536 embryo 08-10hr    5507 embryo 10-12hr    7532 embryo 12-14hr    5040 embryo 14-16hr    3926 embryo 16-18hr    3686 embryo 18-20hr    2572 embryo 20-22hr    1830 embryo 22-24hr    2049 larva L1    2240 larva L2    2929 larva L3 12hr old    2750 larva L3 puffstage 1-2    3073 larva L3 puffstage 3-6    2843 larva L3 puffstage 7-9    3018 white prepupae new    2715 white prepupae 12hr    2458 white prepupae 24hr    2886 pupae 2d postWPP    2906 pupae 3d postWPP    2481 pupae 4d postWPP    1529 adult male 01day    2326 adult male 05day    2331 adult male 30day    2275 adult female 01day    2701 adult female 05day    3228 adult female 30day    3149 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0037108    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0037108 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult organs/tissues expressed at moderate or high levels. Expression at high levels in the following post-embryonic organs or tissues: adult eye, larval fat body, larval/adult salivary gland, larval trachea, adult spermathecae, adult male accessory gland. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, adult fat body, adult ovary, larval/adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0037108 expression level Tissue   Expression Level Larval Central Nervous System    376.9 Larval Midgut    411.9 Larval Hindgut    299.2 Larval Malpighian Tubules    463.3 Larval Fat Body    502.6 Larval Salivary Gland    907.9 Larval Trachea    502.775 Larval Carcass    293.625 Adult Head    358.3 Adult Eye    624.3 Adult Brain    363.9 Adult Thoracic-Abdominal Ganglion    380.9 Adult Crop    243.4 Adult Midgut    498.2 Adult Hindgut    261.9 Adult Malpighian Tubules    382 Adult Fat Body    353.6 Adult Salivary Gland    1920.1 Adult Heart    399.4 Adult VirginFemale Spermatheca    532.8 Adult InseminatedFemale Spermatheca    547.3 Adult Ovary    293.6 Adult Testis    94.9 Adult Male Accessory Gland    1106.3 Adult Carcass    242.7 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    376.9 Larval Midgut    411.9 Larval Hindgut    299.2 Larval Malpighian Tubules    463.3 Larval Fat Body  502.6 Larval Salivary Gland  (907.9) Larval Trachea  502.775 Larval Carcass    293.625 Adult Head    358.3 Adult Eye  (624.3) Adult Brain    363.9 Adult Thoracic-Abdominal Ganglion    380.9 Adult Crop    243.4 Adult Midgut    498.2 Adult Hindgut    261.9 Adult Malpighian Tubules    382 Adult Fat Body    353.6 Adult Salivary Gland  (1920.1) Adult Heart    399.4 Adult VirginFemale Spermatheca  532.8 Adult InseminatedFemale Spermatheca  (547.3) Adult Ovary    293.6 Adult Testis    94.9 Adult Male Accessory Gland  (1106.3) Adult Carcass    242.7 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    376.9 Larval Midgut    411.9 Larval Hindgut    299.2 Larval Malpighian Tubules    463.3 Larval Fat Body    502.6 Larval Salivary Gland    907.9 Larval Trachea    502.775 Larval Carcass    293.625 Adult Head    358.3 Adult Eye    624.3 Adult Brain    363.9 Adult Thoracic-Abdominal Ganglion    380.9 Adult Crop    243.4 Adult Midgut    498.2 Adult Hindgut    261.9 Adult Malpighian Tubules    382 Adult Fat Body    353.6 Adult Salivary Gland  (1920.1) Adult Heart    399.4 Adult VirginFemale Spermatheca    532.8 Adult InseminatedFemale Spermatheca    547.3 Adult Ovary    293.6 Adult Testis    94.9 Adult Male Accessory Gland  (1106.3) Adult Carcass    242.7 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    376.9 Larval Midgut    411.9 Larval Hindgut    299.2 Larval Malpighian Tubules    463.3 Larval Fat Body    502.6 Larval Salivary Gland    907.9 Larval Trachea    502.775 Larval Carcass    293.625 Adult Head    358.3 Adult Eye    624.3 Adult Brain    363.9 Adult Thoracic-Abdominal Ganglion    380.9 Adult Crop    243.4 Adult Midgut    498.2 Adult Hindgut    261.9 Adult Malpighian Tubules    382 Adult Fat Body    353.6 Adult Salivary Gland    1920.1 Adult Heart    399.4 Adult VirginFemale Spermatheca    532.8 Adult InseminatedFemale Spermatheca    547.3 Adult Ovary    293.6 Adult Testis    94.9 Adult Male Accessory Gland    1106.3 Adult Carcass    242.7 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0037108 expression level Tissue   Expression Level Larval Central Nervous System    376.9 Larval Midgut    411.9 Larval Hindgut    299.2 Larval Malpighian Tubules    463.3 Larval Fat Body    502.6 Larval Salivary Gland    907.9 Larval Trachea    502.775 Larval Carcass    293.625 Adult Head    358.3 Adult Eye    624.3 Adult Brain    363.9 Adult Thoracic-Abdominal Ganglion    380.9 Adult Crop    243.4 Adult Midgut    498.2 Adult Hindgut    261.9 Adult Malpighian Tubules    382 Adult Fat Body    353.6 Adult Salivary Gland    1920.1 Adult Heart    399.4 Adult VirginFemale Spermatheca    532.8 Adult InseminatedFemale Spermatheca    547.3 Adult Ovary    293.6 Adult Testis    94.9 Adult Male Accessory Gland    1106.3 Adult Carcass    242.7 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    376.9 Larval Midgut    411.9 Larval Hindgut    299.2 Larval Malpighian Tubules    463.3 Larval Fat Body  502.6 Larval Salivary Gland  (907.9) Larval Trachea  502.775 Larval Carcass    293.625 Adult Head    358.3 Adult Eye  624.3 Adult Brain    363.9 Adult Thoracic-Abdominal Ganglion    380.9 Adult Crop    243.4 Adult Midgut    498.2 Adult Hindgut    261.9 Adult Malpighian Tubules    382 Adult Fat Body    353.6 Adult Salivary Gland  (1920.1) Adult Heart    399.4 Adult VirginFemale Spermatheca  532.8 Adult InseminatedFemale Spermatheca  547.3 Adult Ovary    293.6 Adult Testis    94.9 Adult Male Accessory Gland  (1106.3) Adult Carcass    242.7 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    376.9 Larval Midgut    411.9 Larval Hindgut    299.2 Larval Malpighian Tubules    463.3 Larval Fat Body    502.6 Larval Salivary Gland    907.9 Larval Trachea    502.775 Larval Carcass    293.625 Adult Head    358.3 Adult Eye    624.3 Adult Brain    363.9 Adult Thoracic-Abdominal Ganglion    380.9 Adult Crop    243.4 Adult Midgut    498.2 Adult Hindgut    261.9 Adult Malpighian Tubules    382 Adult Fat Body    353.6 Adult Salivary Gland  (1920.1) Adult Heart    399.4 Adult VirginFemale Spermatheca    532.8 Adult InseminatedFemale Spermatheca    547.3 Adult Ovary    293.6 Adult Testis    94.9 Adult Male Accessory Gland  1106.3 Adult Carcass    242.7 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    376.9 Larval Midgut    411.9 Larval Hindgut    299.2 Larval Malpighian Tubules    463.3 Larval Fat Body    502.6 Larval Salivary Gland    907.9 Larval Trachea    502.775 Larval Carcass    293.625 Adult Head    358.3 Adult Eye    624.3 Adult Brain    363.9 Adult Thoracic-Abdominal Ganglion    380.9 Adult Crop    243.4 Adult Midgut    498.2 Adult Hindgut    261.9 Adult Malpighian Tubules    382 Adult Fat Body    353.6 Adult Salivary Gland    1920.1 Adult Heart    399.4 Adult VirginFemale Spermatheca    532.8 Adult InseminatedFemale Spermatheca    547.3 Adult Ovary    293.6 Adult Testis    94.9 Adult Male Accessory Gland    1106.3 Adult Carcass    242.7 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    358.3   NA  Eye    624.3   NA  Brain    363.9   376.9  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    380.9   NA  Crop    243.4   411.9  Midgut    498.2   299.2  Hindgut    261.9   463.3  Malpighian Tubules    382   502.6  Fat Body    353.6   907.9  Salivary Gland    1920.1   NA  Heart    399.4   502.775  Trachea    NA   NA  VirginFemale Spermatheca    532.8   NA  InseminatedFemale Spermatheca    547.3   NA  Ovary    293.6   NA  Testis    94.9   NA  Male Accessory Gland    1106.3   293.625  Carcass    242.7 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_03
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0037108 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG11306-RA FlyExpress - Embryonic expression images (BDGP data) • Show all FlyExpress processed images for CG11306 Stages(s) 1-3 Stages(s) 7-8 Stages(s) 9-10 Stages(s) 11-12 Stages(s) 13-16
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal, with Scer\GAL41407 CG11306GD2769 lethal, with Scer\GAL4pnr-MD237 CG11306GD2769 lethal | pupal stage, with Scer\GAL4pnr-MD237 CG11306GD2769 Other Phenotypes Allele neuroanatomy defective | larval stage, with Scer\GAL41407 CG11306GD2769 Phenotype manifest in Allele embryonic/larval neuroblast | larval stage, with Scer\GAL41407 CG11306GD2769 ganglion mother cell | larval stage, with Scer\GAL41407 CG11306GD2769
Classical Alleles ( 1 )
For All Classical Alleles Show
Allele of CG11306 Class Mutagen Stocks Known lesion CG11306EY10344 P-element activity 1 --
Alleles Carried on Transgenic Constructs ( 2 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG11306 Class Mutagen Stocks Known lesion CG11306GD2769 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes CG11306KK107035 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD2769} NA P{KK107035} NA
Insertions
	Type of insertions Name Expression data insertion of mobile activating element P{EPgy2}CG11306EY10344 NA
Gene Ontology: Function, Process & Cellular Component ( 3 unique terms )
Terms Based on Experimental Evidence ( 1 term )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
neurogenesis inferred from mutant phenotype (Neumüller et al., 2011)
Cellular Component ( 0 terms)
Terms Based on Predictions or Assertions ( 2 terms )
Molecular Function
CV term Evidence References
alpha-1,2-mannosyltransferase activity inferred from sequence or structural similarity with Saccharomyces ALG11 (FlyBase, 1992-)
Biological Process
CV term Evidence References
biosynthetic process inferred from electronic annotation with InterPro:IPR001296 (FlyBase Curators et al., 2004-)
Cellular Component ( 0 terms)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG11306 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 65646 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0037108 DroID - A comprehensive database of gene and protein interactions. • FBgn0037108 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 40402
Orthologs
Genome-wide drosophilid orthologs	Dana\GF23731 Dere\GG16209 Dgri\GH17189 Dmoj\GI13955 Dper\GL14148 Dpse\GA10904 Dsec\GM22390 Dsim\GD14979 Dvir\GJ13737 Dwil\GK20298
Curated drosophilid orthologs	Dpse\GA10904
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL000559-PA Aedes aegypti (mosquito) AGAP011324-PA Anopheles gambiae (mosquito) XP_624912.2 Apis mellifera (honey bee) XP_001948130.1 Acyrthosiphon pisum (pea aphid) At2g40190.1 Arabidopsis thaliana (wall cress) 28479 Batrachochytrium dendrobatidis (chytrid fungus) 63721 Branchiostoma floridae (lancelet) XP_001896035.1 Brugia malayi (roundworm nematode) BGIBMGA014572-PA Bombyx mori (silk worm) ENSBTAP00000013659 Bos taurus (bovine) CAL0005040 Candida albicans (a form of yeast) CN30790 Caenorhabditis brenneri (small nematode) CBP33121 Caenorhabditis briggsae (nematode) CE26792 Caenorhabditis elegans (worm) ENSCAFP00000006315 Canis familiaris (dog) CAGL0D01122g Candida glabrata (haploid yeast) Chro.40340 Cryptosporidium hominis (obligate parasite) ENSCINP00000023795 Ciona intestinalis (sea squirt) JA12790 Caenorhabditis japonica (nematode) CMI301C Cyanidioschyzon merolae (red alga) cn10331 Cryptococcus neoformans (yeast-like fungus) cgd4_2990 Cryptosporidium parvum (protozoan parasite) CPIJ017415 Culex pipens (mosquito) ENSCPOP00000020514 Cavia porcellus (guinea pig) 178601 Chlamidomonas reinhardtii (green alga) RP12931 Caenorhabditis remanei (nematode) ENSCSAVP00000010798 Ciona savignyi (sedentary tunicate) 156664 Capitella spl (polychaete worm) DDB0231366 Dictyostelium discoideum (amoeba) DEHA2C03982g Debaryomyces Hansenii (yeast) 309592 Daphnia pulex (daphnia) ENSDARP00000049513 Danio rerio (zebra fish) ENSECAP00000015904 Equus caballus (horse) XP_657275 Entamoeba histolytica (anaerobic protozoan) ENSGACP00000019998 Gymnopilus aculeatus (mushroom) ENSGALP00000027453 Gallus gallus (chicken) 111022 Hypsipyla robusta (cedar shoot borer) ENSP00000311392 Homo sapiens (human) ISCW005363-PA Ixodes scapularis (deer tick) KLLA0F03817g Kluyveromyces lactis (yeast) 198678 Lottia gigantea (owl limpet) LmjF35.5250 Leishmania major (virus) 27085 Monocosta brevicollis (choanoflagellate) ENSMODP00000033115 Monodelphis domestica (gray opossum) ENSMUSP00000072382 Mus musculus (house mouse) 124985 Nematostella vectensis (starlet anemone) XP_001603500.1 Nasonia vitripennis (wasp) ENSOANP00000024454 Ornithorynchus anatinus (platypus) ENSORLP00000010326 Oryzias latipes (japanese killifish) LOC_Os12g39340.1 Oryza sativa (asian rice) 2131 Ostreococcus tauri (green alga) PHUM001112-PA Pediculus humanus (human body louse) 196599 Physcomitrella patens (moss) ENSPPYP00000006134 Pongo pygmaeus (orangutan) 72993 Phytophthora ramorum (sudden oak death pathogen) 108303 Phytophthora sojae (root rot pathogen) 570235 Populus trichocarpa (black cottonwood) ENSPTRP00000010027 Pan troglodytes (chimpanzee) ENSRNOP00000017163 Rattus norvegicus (norway rat) 5059727 Sorghum bicolor (sorghum) YNL048W Saccharomyces cerevisiae (budding yeast) Smp_052330 Schistosoma mansoni (trematode parasite) SPCC330.08 Schizosaccharomyces pombe (fission yeast) XP_787277.1 Strongylocentrotus purpuratus (purple sea urchin) 50291 Trichoplax adhaerens (metazoa) XP_969482.1 Tribolium castaneum (red flour beetle) Tc00.1047053506885.10 Trypanosoma cruzi (parasitic trypanosome) ENSTNIP00000017548 Tetraodon nigroviridis (green spotted pufferfish) 269819 Thalassiosira pseudonana (marine diatom) ENSTRUP00000020521 Takifugu rubripes (pufferfish Takifugu) 99.m00116 Tetrahymena thermophila (ciliate protozoa) 94829.m00054 Trichomonas vaginalis (parasitic flagellated protozoan) ENSXETP00000044752 Xenopus tropicalis (frog) YALI0D08558g Yarrowia lipolytica (nonconventional yeast) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • NV14382 NV13298 LH24451 ISCW005363 FBgn0240240 FBgn0237111 FBgn0222295 FBgn0200958 FBgn0186651 FBgn0177260 JGI_V11_309592 FBgn0070960 FBgn0151753 FBgn0136709 FBgn0124659 FBgn0108444 FBgn0100725 CPIJ017415 BGIBMGA014572 ACYPI009192 GB13757 AGAP011324 AAEL000559 PB24987 PHUM288540 GLEAN_15607
Stocks & Reagents
Stocks Listed in FlyBase ( 4 )
Bloomington	17669 y1 w67c23; P{EPgy2}CG11306EY10344/TM3, Sb1 Ser1
VDRC	v104286 P{KK107035}VIE-260B v8447 w1118; P{GD2769}v8447 v8448 w1118; P{GD2769}v8448
Genomic Clones ( 1 )
	BACR26P10 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 74 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	HL02815 RE27026
Other clones	DPiM_HL02815
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	GH13678 GH20889 GH27907 GM04717 HL02586 HL03754 LD28720 RE06382 RE21518 RE32336 RE32831 RE32875 RE56556 RE68550 RH45177 RH64552 SD14451
Other clones	16116 33676 45484 59638 75123 77014 146144 148336 179123 214403.47 214513.39 527200 568895 CK01.25D.F6 CK01.56B.G5 CK01.58C.H12 CK01.104A.G7 CK01.118D.C8 CK01.129A.C4 CK01.129C.A8 EK010406 EK022855 EK045527 EK047662 EK087228 EK090144 EK095532 EK095936 EK144110 EK161244 EK186240 EK207137 EK210150 EK249126 EK307006 EN07445 EN14137 EP03704 EP11945 FGH120G10 FGM310B01 FGX001H02 RP001016255 RP001026790 RP001031515 RP001033100 RP001035898 RP001043679 RP001045279 RP001045334 RP001045372 RP001046031 RP001050011 RP001053320
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0037108 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 40402
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_141083 RefSeq (Proteins) • NP_649340 DDBJ / EMBL / GenBank • AA697579 AAF51756 AAL28560 AAM29441 AW941425 AY061012 AY113436 BI229275 CL526217 Entrez Gene - A searchable database of RefSeq genes. • 40402 UniProtKB/TrEMBL • Q9VP06
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Glycosyl transferase, family 1 (IPR001296)
Linkouts
	BioGRID - A database of protein and genetic interactions • 65646 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0037108 DroID - A comprehensive database of gene and protein interactions. • FBgn0037108 DRSC - Results from RNAi screens. • FBgn0037108 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0037108 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG11306-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0037108 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 40402 InParanoid A subset of ortholog calls from InParanoid. • AAEL000559-PA Aedes aegypti (mosquito) AGAP011324-PA Anopheles gambiae (mosquito) XP_624912.2 Apis mellifera (honey bee) XP_001948130.1 Acyrthosiphon pisum (pea aphid) At2g40190.1 Arabidopsis thaliana (wall cress) 28479 Batrachochytrium dendrobatidis (chytrid fungus) 63721 Branchiostoma floridae (lancelet) XP_001896035.1 Brugia malayi (roundworm nematode) BGIBMGA014572-PA Bombyx mori (silk worm) ENSBTAP00000013659 Bos taurus (bovine) CAL0005040 Candida albicans (a form of yeast) CN30790 Caenorhabditis brenneri (small nematode) CBP33121 Caenorhabditis briggsae (nematode) CE26792 Caenorhabditis elegans (worm) ENSCAFP00000006315 Canis familiaris (dog) CAGL0D01122g Candida glabrata (haploid yeast) Chro.40340 Cryptosporidium hominis (obligate parasite) ENSCINP00000023795 Ciona intestinalis (sea squirt) JA12790 Caenorhabditis japonica (nematode) CMI301C Cyanidioschyzon merolae (red alga) cn10331 Cryptococcus neoformans (yeast-like fungus) cgd4_2990 Cryptosporidium parvum (protozoan parasite) CPIJ017415 Culex pipens (mosquito) ENSCPOP00000020514 Cavia porcellus (guinea pig) 178601 Chlamidomonas reinhardtii (green alga) RP12931 Caenorhabditis remanei (nematode) ENSCSAVP00000010798 Ciona savignyi (sedentary tunicate) 156664 Capitella spl (polychaete worm) DDB0231366 Dictyostelium discoideum (amoeba) DEHA2C03982g Debaryomyces Hansenii (yeast) 309592 Daphnia pulex (daphnia) ENSDARP00000049513 Danio rerio (zebra fish) ENSECAP00000015904 Equus caballus (horse) XP_657275 Entamoeba histolytica (anaerobic protozoan) ENSGACP00000019998 Gymnopilus aculeatus (mushroom) ENSGALP00000027453 Gallus gallus (chicken) 111022 Hypsipyla robusta (cedar shoot borer) ENSP00000311392 Homo sapiens (human) ISCW005363-PA Ixodes scapularis (deer tick) KLLA0F03817g Kluyveromyces lactis (yeast) 198678 Lottia gigantea (owl limpet) LmjF35.5250 Leishmania major (virus) 27085 Monocosta brevicollis (choanoflagellate) ENSMODP00000033115 Monodelphis domestica (gray opossum) ENSMUSP00000072382 Mus musculus (house mouse) 124985 Nematostella vectensis (starlet anemone) XP_001603500.1 Nasonia vitripennis (wasp) ENSOANP00000024454 Ornithorynchus anatinus (platypus) ENSORLP00000010326 Oryzias latipes (japanese killifish) LOC_Os12g39340.1 Oryza sativa (asian rice) 2131 Ostreococcus tauri (green alga) PHUM001112-PA Pediculus humanus (human body louse) 196599 Physcomitrella patens (moss) ENSPPYP00000006134 Pongo pygmaeus (orangutan) 72993 Phytophthora ramorum (sudden oak death pathogen) 108303 Phytophthora sojae (root rot pathogen) 570235 Populus trichocarpa (black cottonwood) ENSPTRP00000010027 Pan troglodytes (chimpanzee) ENSRNOP00000017163 Rattus norvegicus (norway rat) 5059727 Sorghum bicolor (sorghum) YNL048W Saccharomyces cerevisiae (budding yeast) Smp_052330 Schistosoma mansoni (trematode parasite) SPCC330.08 Schizosaccharomyces pombe (fission yeast) XP_787277.1 Strongylocentrotus purpuratus (purple sea urchin) 50291 Trichoplax adhaerens (metazoa) XP_969482.1 Tribolium castaneum (red flour beetle) Tc00.1047053506885.10 Trypanosoma cruzi (parasitic trypanosome) ENSTNIP00000017548 Tetraodon nigroviridis (green spotted pufferfish) 269819 Thalassiosira pseudonana (marine diatom) ENSTRUP00000020521 Takifugu rubripes (pufferfish Takifugu) 99.m00116 Tetrahymena thermophila (ciliate protozoa) 94829.m00054 Trichomonas vaginalis (parasitic flagellated protozoan) ENSXETP00000044752 Xenopus tropicalis (frog) YALI0D08558g Yarrowia lipolytica (nonconventional yeast) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 40402 modMine - Data generated by the modENCODE project. • FBgn0037108 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • NV14382 NV13298 LH24451 ISCW005363 FBgn0240240 FBgn0237111 FBgn0222295 FBgn0200958 FBgn0186651 FBgn0177260 JGI_V11_309592 FBgn0070960 FBgn0151753 FBgn0136709 FBgn0124659 FBgn0108444 FBgn0100725 CPIJ017415 BGIBMGA014572 ACYPI009192 GB13757 AGAP011324 AAEL000559 PB24987 PHUM288540 GLEAN_15607
Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	CG11306 (Harbison et al., 2009, Liu and Lehmann, 2008, Keleman et al., 2009.8.5, Accardo et al., 2004)
Name Synonym	putative alpha-1,2-mannosyltransferase activity (Accardo et al., 2004)
Secondary FlyBase IDs
References ( 15 )
Research paper	Harbison et al., 2009, Nature Genetics 41(3): 371--375 Co-regulated transcriptional networks contribute to natural genetic variation in Drosophila sleep. [FBrf0206746] Liu and Lehmann, 2008, Insect Molec. Biol. 17(2): 91--101 Genes and biological processes controlled by the Drosophila FOXA orthologue Fork head. [FBrf0204414] Accardo et al., 2004, Bioinformatics 20(18): 3293--3301 A computational search for box C/D snoRNA genes in the Drosophila melanogaster genome. [FBrf0187185]
Supplementary material	Neumüller et al., 2011, Cell Stem Cell 8(5): Supplemental Table S1. [FBrf0214431] Khanna et al., 2010, BMC Genomics 11(1): Towards a membrane proteome in Drosophila: a method for the isolation of plasma membrane. [FBrf0210978] The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518] Giot et al., 2003, Science 302(5651): Tables S1 to S7. [FBrf0166452]
Personal communication to FlyBase	Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] FlyBase Curators et al., 2004-, Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. [FBrf0174215]
FlyBase analysis	FlyBase, 1992-, FlyBase curation FlyBase curation. [FBrf0105495]
Computer file	Gene Disruption Project members, 2001-, [title not yet available] [title not yet available] [FBrf0132177] BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. Berkeley Drosophila Genome Project. [FBrf0125078]