FlyBase Gene Report: Dmel\laza

General Information

Symbol

Dmel\laza

Species

D. melanogaster

Name

lazaro

Annotation Symbol

CG11440

Feature Type

protein_coding_gene

FlyBase ID

FBgn0037163

Gene Model Status

Current

Stock Availability

10 publicly available

Enzyme Name (EC)

Phosphatidate phosphatase (3.1.3.4)

Gene Summary

lazaro (laza) encodes a protein involved in phototransduction, response to light intensity and thermotaxis. [Date last reviewed: 2019-08-01] (FlyBase Gene Snapshot)

All Summaries

Gene Snapshot
Alliance
Auto summary
Gene Group
Interactive Fly

Key Links

Genomic Location

Cytogenetic map

79E4-79E4

Sequence location

3L:22,458,816..22,461,131 [-]

Recombination map

3-47

RefSeq locus

NT_037436 REGION:22458816..22461131

Sequence

Get Decorated FASTA

Genomic Maps

JBrowse GBrowse

Help me choose

Other Genome Views

The following external sites may use different assemblies or annotations than FlyBase.

Function

GO Summary Ribbons

Gene Ontology (GO) Annotations (10 terms)

Molecular Function (2 terms)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (2 terms)

CV Term

Evidence

References

enables lipid phosphatase activity

inferred from biological aspect of ancestor with PANTHER:PTN000807400

(assigned by GO_Central )

(Gaudet et al., 2011)

enables phosphatidate phosphatase activity

inferred from biological aspect of ancestor with PANTHER:PTN000017950

(assigned by GO_Central )

(Gaudet et al., 2011)

inferred from sequence or structural similarity with HGNC:9228

(FlyBase Curators, 2008--)

Biological Process (6 terms)

Terms Based on Experimental Evidence (3 terms)

CV Term

Evidence

References

involved_in phototransduction

inferred from mutant phenotype

(Garcia-Murillas et al., 2006, Kwon and Montell, 2006)

inferred from genetic interaction with FLYBASE:rdgB; FB:FBgn0003218

(Garcia-Murillas et al., 2006)

inferred from genetic interaction with FLYBASE:rdgA; FB:FBgn0261549

(Garcia-Murillas et al., 2006)

involved_in response to light intensity

inferred from mutant phenotype

(Kwon and Montell, 2006)

involved_in thermotaxis

inferred from direct assay

(Kwon et al., 2008)

Terms Based on Predictions or Assertions (3 terms)

CV Term

Evidence

References

involved_in phospholipid dephosphorylation

inferred from biological aspect of ancestor with PANTHER:PTN000807400

(assigned by GO_Central )

(Gaudet et al., 2011)

involved_in phospholipid metabolic process

inferred from biological aspect of ancestor with PANTHER:PTN000807400

(assigned by GO_Central )

(Gaudet et al., 2011)

involved_in signal transduction

inferred from biological aspect of ancestor with PANTHER:PTN000807400

(assigned by GO_Central )

(Gaudet et al., 2011)

Cellular Component (2 terms)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (2 terms)

CV Term

Evidence

References

is_active_in integral component of plasma membrane

inferred from biological aspect of ancestor with PANTHER:PTN000807400

(assigned by GO_Central )

(Gaudet et al., 2011)

located_in membrane

inferred from sequence or structural similarity with HGNC:9228

(FlyBase Curators, 2008--)

Gene Group (FlyBase)

LIPID PHOSPHATE PHOSPHATASES

Protein Family (UniProt)

Protein Signatures (InterPro)

Catalytic Activity (EC)

Experimental Evidence

Predictions / Assertions

A 1,2-diacylglycerol 3-phosphate + H(2)O = a 1,2-diacyl-sn-glycerol + phosphate (3.1.3.4)

Summaries

Gene Snapshot

lazaro (laza) encodes a protein involved in phototransduction, response to light intensity and thermotaxis. [Date last reviewed: 2019-08-01]

Gene Group (FlyBase)

LIPID PHOSPHATE PHOSPHATASES -: Lipid phosphate phosphatases (LPP) are integral membrane proteins, with six putative transmembrane domains, that catalyze the dephosphorylation of a variety of lipid phosphates. (Adapted from FBrf0191316 and PMID:25814022).

Summary (Interactive Fly)

lipid phosphate phosphohydrolase that functions during phototransduction - along with regulates amplification and response termination during phototransduction

Interactive Fly

Gene Model and Products

Number of Transcripts

Number of Unique Polypeptides

Please see the JBrowse view of Dmel\laza for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)

Isoform displayed:

Pfam protein domains

InterPro name

classification

start

end

Protein Domains (via SMART)

Isoform displayed:

SMART protein domains

InterPro name

classification

start

end

Comments on Gene Model

Gene model reviewed during 5.45

Sequence Ontology: Class of Gene

nuclear_gene

protein_coding_gene

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Assoc. CDS (aa)

laza-RA

FBtr0078508

NM_141134

2316

334

Additional Transcript Data and Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

RefSeq ID

GenBank

laza-PA

FBpp0078160

37.8

334

7.16

NP_649391

AAF51828

Polypeptides with Identical Sequences

There is only one protein coding transcript and one polypeptide associated with this gene

Additional Polypeptide Data and Comments

Reported size (kDa)

Comments

External Data

Crossreferences

InterPro - A database of protein families, domains and functional sites

Linkouts

Sequences Consistent with the Gene Model

Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\laza using the Feature Mapper tool.

External Data

Crossreferences

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

laza_1

Linkouts

Expression Data

Expression Summary Ribbons

Colored tiles in ribbon indicate that expression data has been curated by FlyBase for that anatomical location. Colorless tiles indicate that there is no curated data for that location.

For complete stage-specific expression data, view the modENCODE Development RNA-Seq section under High-Throughput Expression below.

Transcript Expression

expression microarray

Stage

Tissue/Position (including subcellular localization)

Reference

adult stage

eye

(Xu et al., 2004)

in situ

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 11 -- 12

midgut interstitial cell primordium

(Fisher et al., 2012)

embryonic stage 13 -- 16

embryonic hindgut

(Fisher et al., 2012)

embryonic large intestine

(Fisher et al., 2012)

embryonic proventriculus

(Fisher et al., 2012)

embryonic/larval midgut interstitial cell

(Fisher et al., 2012)

Additional Descriptive Data

Eye-enriched transcripts determined by ratio of expression level in wild-type heads. versus expression level in so heads.

(Xu et al., 2004)

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Evidence

References

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

GBrowse - Visual display of RNA-Seq signals

View Dmel\laza in GBrowse 2

RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region

View exonic expression by developmental stage for Dmel\laza

View exonic expression by tissue for Dmel\laza

Bulk Downloads

RNA-Seq RPKM values for all genes

Reference

See Gelbart and Emmert, 2013 for analysis details and data files for all genes.

Developmental Proteome: Life Cycle

Developmental Proteome: Embryogenesis

External Data and Images

Linkouts

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0037163

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

40468/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0037163

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0037163

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0037163

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG11440

Flygut - An atlas of the Drosophila adult midgut

FBgn0037163

Images

FlyExpress - Embryonic expression images (BDGP data)

Show all FlyExpress processed images for Dmel\laza

Stages(s) 11-12
Stages(s) 13-16

FlyBase Wiki

Image Based Resources

Alleles, Insertions, Transgenic Constructs, and Aberrations

Classical and Insertion Alleles ( 6 )

For All Classical and Insertion Alleles Show

Other relevant insertions

Transgenic Constructs ( 9 )

For All Alleles Carried on Transgenic Constructs Show

Transgenic constructs containing/affecting coding region of laza

Transgenic constructs containing regulatory region of laza

Aberrations (Deficiencies and Duplications) ( 0 )

Inferred from experimentation ( 0 )

Inferred from location ( 0 )

Alleles Representing Disease-Implicated Variants

Phenotypes

For more details about a specific phenotype click on the relevant allele symbol.

Lethality

Allele

viable

viable, with Dcr-2^UAS.cDa, Scer\GAL4^elav.PLu

laza^GD2778

viable, with Scer\GAL4^Mef2.PR

laza^GD2778

viable, with Scer\GAL4^pnr-MD237

laza^GD2778

Sterility

Allele

fertile

laza^EY04417

Other Phenotypes

Allele

abnormal neurophysiology

abnormal thermotaxis

laza¹

Phenotype manifest in

Allele

eye

rhabdomere

laza²²

Orthologs

Downloads

Download All DIOPT Orthologs

Download All OrthoDB Orthologs

Human Orthologs (via DIOPT v8.0)

Homo sapiens (Human) (13)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Hsap\PLPP1

8 of 15

Yes

Hsap\PLPP3

8 of 15

Yes

7 of 15

5 of 15

4 of 15

4 of 15

Yes

Hsap\PLPPR2

4 of 15

Yes

Hsap\PLPPR3

4 of 15

Yes

Hsap\PLPPR4

4 of 15

Yes

Hsap\PLPPR5

4 of 15

Yes

Hsap\DOLPP1

1 of 15

Yes

Hsap\SGPP1

1 of 15

Yes

Hsap\SGPP2

1 of 15

Yes

Model Organism Orthologs (via DIOPT v8.0)

Mus musculus (laboratory mouse) (14)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Mmus\Plpp1

8 of 15

Yes

Mmus\Plpp3

8 of 15

Yes

7 of 15

5 of 15

4 of 15

4 of 15

Yes

Mmus\Plppr2

4 of 15

Mmus\Plppr3

4 of 15

Yes

Mmus\Plppr4

3 of 15

Mmus\Plppr5

3 of 15

Mmus\Dolpp1

1 of 15

Yes

Mmus\Sgpp1

1 of 15

Yes

Mmus\Sgpp2

1 of 15

Yes

Mmus\Tom1l2

1 of 15

Rattus norvegicus (Norway rat) (13)

Rnor\Plpp3

7 of 13

Yes

Rnor\Plpp1

6 of 13

Rnor\Plpp2

6 of 13

Rnor\Plppr1

4 of 13

Yes

Rnor\Plppr2

4 of 13

Yes

Rnor\Plppr3

4 of 13

Yes

Rnor\Plppr4

4 of 13

Yes

Rnor\Plppr5

4 of 13

Yes

3 of 13

3 of 13

1 of 13

1 of 13

Yes

Rnor\Sgpp2

1 of 13

Yes

Xenopus tropicalis (Western clawed frog) (12)

Xtro\plpp3

8 of 12

Yes

Xtro\LOC100135382

7 of 12

Yes

Xtro\plpp1

7 of 12

Yes

Xtro\plpp2

7 of 12

Xtro\plpp5

4 of 12

Xtro\plppr2

4 of 12

Yes

Xtro\plppr3

4 of 12

Yes

Xtro\plppr4

4 of 12

Yes

Xtro\plppr5

4 of 12

Yes

Xtro\plpp4

3 of 12

Xtro\plppr1

2 of 12

Yes

Xtro\dolpp1

1 of 12

Yes

Danio rerio (Zebrafish) (21)

Drer\plpp2b

8 of 15

Yes

7 of 15

7 of 15

7 of 15

6 of 15

6 of 15

4 of 15

Yes

Drer\plppr2a

4 of 15

Yes

Drer\plppr2b

4 of 15

Yes

Drer\plppr3a

4 of 15

Yes

Drer\plppr3b

4 of 15

Yes

Drer\plppr4a

4 of 15

Yes

Drer\plppr5a

4 of 15

Yes

Drer\LOC571722

3 of 15

Yes

Drer\plpp4

3 of 15

Drer\plpp5

3 of 15

Drer\plppr5b

3 of 15

Yes

Drer\dolpp1

1 of 15

Yes

Drer\sgpp1

1 of 15

Yes

Drer\sgpp2

1 of 15

Yes

Drer\si:ch211-212g7.6

1 of 15

Yes

Caenorhabditis elegans (Nematode, roundworm) (5)

Cele\plpp-1.1

7 of 15

Yes

Cele\plpp-1.2

7 of 15

Yes

Cele\plpp-1.3

5 of 15

Yes

Cele\plpr-1

3 of 15

Yes

Cele\mbtr-1

1 of 15

Arabidopsis thaliana (thale-cress) (4)

Atha\LPP2

2 of 9

Yes

Atha\LPP3

2 of 9

Yes

Atha\LPP4

2 of 9

Yes

Atha\PAP1

2 of 9

Yes

Saccharomyces cerevisiae (Brewer's yeast) (5)

Scer\DPP1

5 of 15

Yes

Scer\LPP1

4 of 15

Scer\CAX4

1 of 15

Yes

Scer\LCB3

1 of 15

Yes

Scer\YSR3

1 of 15

Yes

Schizosaccharomyces pombe (Fission yeast) (1)

Spom\SPBC409.18

3 of 12

Yes

Ortholog(s) in Drosophila Species (via OrthoDB v9.1) ( EOG09190EDP )

Organism

Common Name

Gene

AAA Syntenic Ortholog

Multiple Dmel Genes in this Orthologous Group

Drosophila suzukii

Spotted wing Drosophila

Drosophila simulans

Drosophila sechellia

Drosophila erecta

Drosophila yakuba

Drosophila ananassae

Drosophila pseudoobscura pseudoobscura

Dpse\GA11006

Drosophila persimilis

Dper\GL23307

Drosophila willistoni

Dwil\GK17452

Drosophila virilis

Dvir\GJ13711

Drosophila mojavensis

Dmoj\GI13921

Drosophila grimshawi

Dgri\GH14815

Orthologs in non-Drosophila Dipterans (via OrthoDB v9.1) ( EOG091508KB )

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Musca domestica

House fly

Mdoa\17013650

Musca domestica

House fly

Mdoa\17010079

Glossina morsitans

Tsetse fly

Gmor\GMOY012085

Lucilia cuprina

Australian sheep blowfly

Lcup\FF38_12297

Orthologs in non-Dipteran Insects (via OrthoDB v9.1) ( None identified )

No non-Dipteran orthologies identified

Orthologs in non-Insect Arthropods (via OrthoDB v9.1) ( EOG090X0CQF )

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Ixodes scapularis

Black-legged tick

Isca\ISCW015634

Stegodyphus mimosarum

African social velvet spider

Smim\KFM74477.1

Tetranychus urticae

Two-spotted spider mite

Turt\tetur05g06520

Tetranychus urticae

Two-spotted spider mite

Turt\tetur01g01750

Daphnia pulex

Water flea

Dpux\DAPPUDRAFT_197078

Daphnia pulex

Water flea

Dpux\DAPPUDRAFT_319297

Daphnia pulex

Water flea

Dpux\DAPPUDRAFT_319295

Daphnia pulex

Water flea

Dpux\DAPPUDRAFT_319296

Orthologs in non-Arthropod Metazoa (via OrthoDB v9.1) ( EOG091G0K5H )

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Strongylocentrotus purpuratus

Purple sea urchin

Spur\Sp-Ppap2b

Ciona intestinalis

Vase tunicate

Cint\LOC100177985

Gallus gallus

Domestic chicken

Ggal\PPAP2B

Gallus gallus

Domestic chicken

Ggal\PPAP2A

Gallus gallus

Domestic chicken

Ggal\ENSGALG00000026834

Paralogs

Downloads

Download All DIOPT Paralogs

Paralogs (via DIOPT v8.0)

Drosophila melanogaster (Fruit fly) (7)

Gene Symbol

Score

Source

Alignment

8 of 10

6 of 10

6 of 10

6 of 10

6 of 10

6 of 10

wun

6 of 10

Human Disease Associations

FlyBase Human Disease Model Reports

Disease Model Summary Ribbon

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Allele

Disease

Evidence

References

Potential Models Based on Orthology ( 0 )

Human Ortholog

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Allele

Disease

Interaction

References

Disease Associations of Human Orthologs (via DIOPT v8.0 and OMIM)

Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.

Homo sapiens (Human)

Gene name

Score

OMIM

OMIM Phenotype

DO term

Complementation?

Transgene?

PLPP1; phospholipid phosphatase 1

8 of 15

607124

PLPP3; phospholipid phosphatase 3

8 of 15

607125

PLPP2; phospholipid phosphatase 2

7 of 15

607126

PLPP5; phospholipid phosphatase 5

5 of 15

610626

PLPP4; phospholipid phosphatase 4

4 of 15

PLPPR1; phospholipid phosphatase related 1

4 of 15

PLPPR2; phospholipid phosphatase related 2

4 of 15

PLPPR3; phospholipid phosphatase related 3

4 of 15

610391

PLPPR4; phospholipid phosphatase related 4

4 of 15

607813

PLPPR5; phospholipid phosphatase related 5

4 of 15

617287

Functional Complementation Data

Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.

Interactions

Summary of Physical Interactions

esyN Network Diagram

Interactions Browser

Summary of Genetic Interactions

esyN Network Diagram

esyN Network Key:

Suppression

Enhancement

View in Interactions Browser

Please look at the allele data for full details of the genetic interactions

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

Pld

suppressible

laza

(Thakur et al., 2016)

rdgA

enhanceable

laza

(Garcia-Murillas et al., 2006, Garcia-Murillas et al., 2006)

rdgA

suppressible

laza

(Garcia-Murillas et al., 2006, Kwon and Montell, 2006)

rdgB

suppressible

laza

(Garcia-Murillas et al., 2006)

External Data

Linkouts

DroID - A comprehensive database of gene and protein interactions.

FBgn0037163

MIST (genetic) - An integrated Molecular Interaction Database

laza

Pathways

Signaling Pathways (FlyBase)

Metabolic Pathways

FlyCyc Pathways - Pathways from a BioCyc PGDB for Dmel

diacylglycerol and triacylglycerol biosynthesis

FlyMet - A comprehensive tissue-specific metabolomics resource for Drosophila.

FBgn0037163

KEGG Pathways - Wiring diagrams of molecular interactions, reactions and relations.

Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.

Sphingolipid de novo biosynthesis

External Data

Linkouts

Genomic Location and Detailed Mapping Data

Chromosome (arm)

Recombination map

3-47

Cytogenetic map

79E4-79E4

Sequence location

3L:22,458,816..22,461,131 [-]

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

79E4-79E4

Limits computationally determined from genome sequence between P{lacW}l(3)j1B10^j1B10 and P{lacW}l(3)j2C4^j2C4

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

3-47

(FlyBase, 2016)

3-44.0

(Comeron et al., 2012)

Left of (cM)

Right of (cM)

Notes

Stocks and Reagents

Stocks (10)

Bloomington

24499

w^*; laza¹

24500

w^*; laza²

16604

y¹ w^67c23; P{EPgy2}laza^EY04417

68046

y¹ sc^* v¹ sev²¹; P{TOE.GS00429}attP40

77318

y¹ sc^* v¹ sev²¹; P{TKO.GS01129}attP40

32515

y¹ sc^* v¹ sev²¹; P{TRiP.HMS00519}attP2

FlyORF

F002367

M{UAS-laza.ORF.3xHA.GW}ZH-86Fb

Kyoto

125680

w¹¹¹⁸; P{RS5}laza^5-HA-2795

VDRC

v109898

P{KK111217}VIE-260B

v42594

w¹¹¹⁸; P{GD2778}v42594

Genomic Clones (22)

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones (49)

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequenced

BDGP DGC clones

HL01743

Other clones

Drosophila Genomics Resource Center cDNA clones

For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

FBgn0037163

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

RNAi and Array Information

Linkouts

DRSC - Results frm RNAi screens

FBgn0037163

GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents

40468

Antibody Information

Laboratory Generated Antibodies

Commercially Available Antibodies

Other Information

Relationship to Other Genes

Source for database identify of

Source for identity of: laza CG11440

(Kwon and Montell, 2006)

Source for database merge of

Additional comments

Other Comments

Gene expression is increased in response to the presence of either one or two copies of Scer\GAL4^hs.PB.

(Liu and Lehmann, 2008)

Origin and Etymology

Discoverer

Etymology

Owing to the ability of mutants in this gene to rescue degeneration in blind mutants of the rdgA gene, this gene is named "lazaro" (laza). This name derives from the Spanish novel "Lazarillo de Tormes", in which Lazaro is the boy servant of a blind man and helps him to see.

(Garcia-Murillas et al., 2006)

The gene is referred to as lazaro (laza), as the name is based on the novel Lazarillo de Tormes, in which the orphan boy Lazaro, helps a blind man see.

(Kwon and Montell, 2006)

Identification

External Crossreferences and Linkouts ( 40 )

Sequence Crossreferences

NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.

40468

GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.

GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.

RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.

UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information

Q9VNU2

Other crossreferences

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0037163

Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones

FBgn0037163

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

40468/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0037163

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

laza_1

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0037163

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0037163

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG11440

Flygut - An atlas of the Drosophila adult midgut

FBgn0037163

FlyMet - A comprehensive tissue-specific metabolomics resource for Drosophila.

FBgn0037163

GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents

40468

InterPro - A database of protein families, domains and functional sites

KEGG Genes - Molecular building blocks of life in the genomic space.

Dmel_CG11440

MARRVEL_MODEL - MARRVEL (model organism gene)

40468

modMine - A data warehouse for the modENCODE project

FBgn0037163

Linkouts

DroID - A comprehensive database of gene and protein interactions.

FBgn0037163

DRSC - Results frm RNAi screens

FBgn0037163

FlyCyc Genes - Genes from a BioCyc PGDB for Dmel

FBGN0037163

FlyCyc Pathways - Pathways from a BioCyc PGDB for Dmel

diacylglycerol and triacylglycerol biosynthesis

FlyMine - An integrated database for Drosophila genomics

FBgn0037163

Interactive Fly - A cyberspace guide to Drosophila development and metazoan evolution

Interactive Fly

KEGG Pathways - Wiring diagrams of molecular interactions, reactions and relations.

MIST (genetic) - An integrated Molecular Interaction Database

laza

Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.

Sphingolipid de novo biosynthesis

Synonyms and Secondary IDs (8)

Reported As

Symbol Synonym

CG11440

(Ni et al., 2010.12.1, Keleman et al., 2009.8.5, Bakal et al., 2008, Liu and Lehmann, 2008, Garcia-Murillas et al., 2006, Kwon and Montell, 2006)

LPP

(Coelho et al., 2013)

LPP-like

(Garcia-Murillas et al., 2006)

Laza

(Kwon and Montell, 2006)

WUN-like

(Morrison et al., 2000)

laza

(Lehmann, 2021, Wat et al., 2020, Katz and Minke, 2018, Suratekar et al., 2018, Transgenic RNAi Project members, 2017-, Thakur et al., 2016, Japanese National Institute of Genetics, 2012.5.21, Senthilan et al., 2012, Napoletano et al., 2011, Bao and Friedrich, 2009, Kwon et al., 2008, Garcia-Murillas et al., 2006, Garcia-Murillas et al., 2006, Kwon and Montell, 2006)

Name Synonyms

CG11440

Lazaro

(Kwon and Montell, 2006)

lazaro

(Coelho et al., 2013, Bao and Friedrich, 2009, Garcia-Murillas et al., 2006, Kwon and Montell, 2006)

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